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Search of human proteins with 24497487
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens]
(332 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens] 659 0.0
gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] 659 0.0
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 284 9e-77
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 283 2e-76
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 271 6e-73
gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 263 2e-70
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 261 8e-70
gi|211059435 solute carrier family 22, member 24 [Homo sapiens] 256 2e-68
gi|153791484 putative UST1-like organic anion transporter [Homo ... 232 4e-61
gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 231 7e-61
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 229 3e-60
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 228 6e-60
gi|42542386 solute carrier family 22 (organic anion/cation trans... 223 2e-58
gi|166064021 solute carrier family 22 (organic anion transporter... 211 6e-55
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 197 1e-50
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 197 1e-50
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 173 2e-43
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 162 4e-40
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 155 4e-38
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 146 3e-35
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 141 7e-34
gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 137 1e-32
gi|31542327 solute carrier family 22, member 16 [Homo sapiens] 132 3e-31
gi|157426885 organic cation transporter like 4 [Homo sapiens] 117 2e-26
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 110 2e-24
gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1... 90 3e-18
gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6... 86 5e-17
gi|63999576 solute carrier family 22, member 17 isoform b [Homo ... 76 5e-14
gi|21361834 solute carrier family 22, member 17 isoform a [Homo ... 72 5e-13
gi|24308167 SV2 related protein [Homo sapiens] 70 2e-12
>gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens]
Length = 332
Score = 659 bits (1701), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE
Sbjct: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL
Sbjct: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS
Sbjct: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP
Sbjct: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL
Sbjct: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
Query: 301 PLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF 332
PLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF
Sbjct: 301 PLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF 332
>gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]
Length = 553
Score = 659 bits (1701), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE
Sbjct: 222 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 281
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL
Sbjct: 282 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 341
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS
Sbjct: 342 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 401
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP
Sbjct: 402 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 461
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL
Sbjct: 462 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 521
Query: 301 PLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF 332
PLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF
Sbjct: 522 PLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF 553
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 284 bits (726), Expect = 9e-77
Identities = 145/316 (45%), Positives = 205/316 (64%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW R V TL +S G L A VAY V W LQL+VS PFF F+YSW+ E
Sbjct: 211 VEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIE 270
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARW ++GRLD L+ L RVA INGK L+ EVL +++++EL+MG+ AS LL
Sbjct: 271 SARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELL 330
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R P LR ++ WFA F ++GL +DLQ G +I+L+Q+ G VD+PAK+ L+++
Sbjct: 331 RCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVIN 390
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
LGRRP A+LLLAG+CIL N ++P + +R++LAVLG G + A+F CI +Y+ EL+P
Sbjct: 391 SLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYP 450
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
T++R T +G+G AR G+I+ PLV + P +PL +YG VPV + +LLPET
Sbjct: 451 TMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQ 510
Query: 301 PLPDTIQDVQNQAVKK 316
PLPDT+QD++++ K+
Sbjct: 511 PLPDTVQDLESRKGKQ 526
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 283 bits (724), Expect = 2e-76
Identities = 144/312 (46%), Positives = 203/312 (65%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW R V TL +S G L A VAY V W LQL+VS PFF F+YSW+ E
Sbjct: 211 VEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIE 270
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARW ++GRLD L+ L RVA INGK L+ EVL +++++EL+MG+ AS LL
Sbjct: 271 SARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELL 330
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R P LR ++ WFA F ++GL +DLQ G +I+L+Q+ G VD+PAK+ L+++
Sbjct: 331 RCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVIN 390
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
LGRRP A+LLLAG+CIL N ++P + +R++LAVLG G + A+F CI +Y+ EL+P
Sbjct: 391 SLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYP 450
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
T++R T +G+G AR G+I+ PLV + P +PL +YG VPV + +LLPET
Sbjct: 451 TMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQ 510
Query: 301 PLPDTIQDVQNQ 312
PLPDT+QD++++
Sbjct: 511 PLPDTVQDLESR 522
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 271 bits (693), Expect = 6e-73
Identities = 148/313 (47%), Positives = 196/313 (62%), Gaps = 2/313 (0%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EWT R + MT+ FS G +A+ +RDW LQL SVPFF L SWWL E
Sbjct: 219 VEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPE 278
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARWL+ G+ D LQEL +VA ING ++ LT EVL+S+++EE++ + P S+ L
Sbjct: 279 SARWLIIKGKPDQALQELRKVARINGHKEAKN-LTIEVLMSSVKEEVASAKEPRSVLDLF 337
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
+P LR+R+C + F+ +++GL DLQ+LG +IFLLQ G VD + LLLS
Sbjct: 338 CVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLS 397
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
LGRR A S +AGL ILAN LVP ++ LR AVLG G G + TC+TIY +ELFP
Sbjct: 398 FLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFP 457
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAAL-LLPETQS 299
T +RMTA G+ R GA++GPL+ + P LP L+YG + + S L L LPETQ
Sbjct: 458 TPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQG 517
Query: 300 LPLPDTIQDVQNQ 312
LPLPDTIQD+++Q
Sbjct: 518 LPLPDTIQDLESQ 530
>gi|148664184 solute carrier family 22, member 10 [Homo sapiens]
Length = 541
Score = 263 bits (671), Expect = 2e-70
Identities = 145/311 (46%), Positives = 191/311 (61%)
Query: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
EW ++ LV+ L+S S G + +AY RDW L +V SVPFF+ FL S WL ES
Sbjct: 223 EWIRPNSKALVVILSSGALSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVES 282
Query: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLR 121
ARWL+ T +LD GL+ L +VA NG ++TL EV+ S M+EEL Q ++ L R
Sbjct: 283 ARWLIITNKLDEGLKALRKVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTTVCDLFR 342
Query: 122 MPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH 181
P +R R CI FA F+G ++LQ +GSNIFLLQ+ G V + + ALL L+H
Sbjct: 343 NPSMRKRICILVFLRFANTIPFYGTMVNLQHVGSNIFLLQVLYGAVALIVRCLALLTLNH 402
Query: 182 LGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPT 241
+GRR + + L GL ILANT VP EM LR ALA LG+G A F+ + ++ EL PT
Sbjct: 403 MGRRISQILFMFLVGLSILANTFVPKEMQTLRVALACLGIGCSAATFSSVAVHFIELIPT 462
Query: 242 VLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLP 301
VLR A G+ A+R GA L PL+ L V LP ++YG P++ GL LLPET++LP
Sbjct: 463 VLRARASGIDLTASRIGAALAPLLMTLTVFFTTLPWIIYGIFPIIGGLIVFLLPETKNLP 522
Query: 302 LPDTIQDVQNQ 312
LPDTI+DV+NQ
Sbjct: 523 LPDTIKDVENQ 533
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 261 bits (666), Expect = 8e-70
Identities = 130/315 (41%), Positives = 202/315 (64%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW R R ++ T ++FG + +AY + W LQL VS+PFF+ FL SWW E
Sbjct: 199 VEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPE 258
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
S RWL+ +G+ L+ L RVA NGK + L+ E L +++E+S+ + + L
Sbjct: 259 SIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLF 318
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R+P LR T +L WFA GF ++ LA+ ++ G N+++LQ+ G VD+PAK +L LS
Sbjct: 319 RIPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLS 378
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
+LGR T AA+LLLAG ILA T VP ++ +R+ LAV G G + ++F+C+ +Y+SEL+P
Sbjct: 379 YLGRHTTQAAALLLAGGAILALTFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTSELYP 438
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
TV+R T +G+ + R G+++ PLV++ G P++P ++YG +L G AAL LPET +
Sbjct: 439 TVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPETLNQ 498
Query: 301 PLPDTIQDVQNQAVK 315
PLP+TI+D++N +++
Sbjct: 499 PLPETIEDLENWSLR 513
>gi|211059435 solute carrier family 22, member 24 [Homo sapiens]
Length = 551
Score = 256 bits (655), Expect = 2e-68
Identities = 143/334 (42%), Positives = 203/334 (60%), Gaps = 6/334 (1%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EWT R+R + + + +S G L +A+ ++DW +LQL VS P + FL SW + E
Sbjct: 222 LEWTLPRSRSMTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVE 281
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARWL+ +LD GL+EL RVA INGK ++TLT E++ S M++EL + S+ +L
Sbjct: 282 SARWLIINNQLDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLF 341
Query: 121 RMPGLRFRTCISTLCWFAFGFT--FFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLL 178
R P LR R + LC+ F T F+GL L+LQ LGSN+ L Q+ G V A+ +LL
Sbjct: 342 RAPKLRMR--VFGLCFVRFAITVPFYGLILNLQHLGSNVSLFQILCGAVTFTARCVSLLT 399
Query: 179 LSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSEL 238
L+H+GRR + GL IL NT +P EM LR LA LG+G V AA +++ +EL
Sbjct: 400 LNHMGRRISQILFTFPVGLFILVNTFLPQEMQILRVVLATLGIGSVSAASNSASVHHNEL 459
Query: 239 FPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQ 298
PT+LR T G+ ++ R GA L PL+ L + P LP + YG P+L+ LLLPET+
Sbjct: 460 VPTILRSTVAGINAVSGRTGAALAPLLMTLMAYSPHLPWISYGVFPILAVPVILLLPETR 519
Query: 299 SLPLPDTIQDVQNQAVKKATHGTLGNSVLKSTQF 332
LPLP+TIQDV+N+ K + + ++ +K TQF
Sbjct: 520 DLPLPNTIQDVENE--KDSRNIKQEDTCMKVTQF 551
>gi|153791484 putative UST1-like organic anion transporter [Homo
sapiens]
Length = 547
Score = 232 bits (591), Expect = 4e-61
Identities = 130/314 (41%), Positives = 180/314 (57%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW + + +TL S GH ++A+ +RD +LQLV+S P F+ FL+S WLAE
Sbjct: 222 VEWITHQFCAMALTLTLCAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAE 281
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARWL+ + + GL+EL + A NG +D LT EVL S M++EL Q SL LL
Sbjct: 282 SARWLIINNKPEEGLKELRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELL 341
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R+P + R C + FA F+GL L LQ LG+N+FLLQ G V + A A L+
Sbjct: 342 RIPNICKRICFLSFVRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPWALN 401
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
H+ RR + + L C+LA VP EM LR LA LG+G TC T +EL P
Sbjct: 402 HMSRRLSQMLLMFLLATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIP 461
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
+++R A G+ A G L L+ +L ++ LP ++YG +LSGL LLLPET++
Sbjct: 462 SIIRGRATGITGNFANIGGALASLMMILSIYSRPLPWIIYGVFAILSGLVVLLLPETRNQ 521
Query: 301 PLPDTIQDVQNQAV 314
PL D+IQDV+N+ V
Sbjct: 522 PLLDSIQDVENEGV 535
>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
Length = 555
Score = 231 bits (589), Expect = 7e-61
Identities = 117/312 (37%), Positives = 184/312 (58%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW R R + L F+ G + A VAY +R W LQ +S PF + FLYSWWL E
Sbjct: 213 VEWMPTRGRTVAGILLGYSFTLGQLILAGVAYLIRPWRCLQFAISAPFLIFFLYSWWLPE 272
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
S+RWLL G+ +Q L +VAA+NG+ + LT EV+ S ++ E + S+ L
Sbjct: 273 SSRWLLLHGKSQLAVQNLQKVAAMNGRKEEGERLTKEVMSSYIQSEFASVCTSNSILDLF 332
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R P +R TC + WF+ ++GLA+DLQ G +++L+Q G+++ PA + A +
Sbjct: 333 RTPAIRKVTCCLMVIWFSNSVAYYGLAMDLQKFGLSLYLVQALFGIINTPAMLVATATMI 392
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
++GRR T+A+ L+LAGL ++AN VP L +A A LG G + ++F C+ +++ EL+P
Sbjct: 393 YVGRRATVASFLILAGLMVIANMFVPEGTQILCTAQAALGKGCLASSFICVYLFTGELYP 452
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
T +R +G + AR G + PLV LG + LP + +G +L+GLA +L ET+++
Sbjct: 453 TEIRQMGMGFASVHARLGGLTAPLVTTLGEYSTILPPVSFGATAILAGLAVCVLTETRNM 512
Query: 301 PLPDTIQDVQNQ 312
PL +TI ++ +
Sbjct: 513 PLVETIAAMERR 524
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 229 bits (583), Expect = 3e-60
Identities = 128/316 (40%), Positives = 179/316 (56%), Gaps = 44/316 (13%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW R V TL +S G L A VAY V W LQL+VS PFF F+YSW+ E
Sbjct: 211 VEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIE 270
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARW ++GRLD L+ L RVA INGK L+ EVL +++++EL+MG+ AS LL
Sbjct: 271 SARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELL 330
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R P LR ++ WFA F ++GL +DLQ G +I+L+Q+ G VD+PAK+ L+++
Sbjct: 331 RCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVIN 390
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
LGRRP A+LLLAG+CIL N ++P + +R++LAVLG G + A+F CI +Y+ EL+P
Sbjct: 391 SLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYP 450
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
T++R V LLPET
Sbjct: 451 TMIRAVTV--------------------------------------------LLPETLGQ 466
Query: 301 PLPDTIQDVQNQAVKK 316
PLPDT+QD++++ K+
Sbjct: 467 PLPDTVQDLESRKGKQ 482
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 228 bits (581), Expect = 6e-60
Identities = 127/312 (40%), Positives = 177/312 (56%), Gaps = 44/312 (14%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW R V TL +S G L A VAY V W LQL+VS PFF F+YSW+ E
Sbjct: 211 VEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIE 270
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARW ++GRLD L+ L RVA INGK L+ EVL +++++EL+MG+ AS LL
Sbjct: 271 SARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELL 330
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R P LR ++ WFA F ++GL +DLQ G +I+L+Q+ G VD+PAK+ L+++
Sbjct: 331 RCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVIN 390
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
LGRRP A+LLLAG+CIL N ++P + +R++LAVLG G + A+F CI +Y+ EL+P
Sbjct: 391 SLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYP 450
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
T++R V LLPET
Sbjct: 451 TMIRAVTV--------------------------------------------LLPETLGQ 466
Query: 301 PLPDTIQDVQNQ 312
PLPDT+QD++++
Sbjct: 467 PLPDTVQDLESR 478
>gi|42542386 solute carrier family 22 (organic anion/cation
transporter), member 9 [Homo sapiens]
Length = 553
Score = 223 bits (567), Expect = 2e-58
Identities = 127/312 (40%), Positives = 178/312 (57%), Gaps = 1/312 (0%)
Query: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
EW R + + +TL A +A+ +RDW +LQLVVSVP+F+ FL S WL ES
Sbjct: 223 EWATHRFQAMGITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLES 282
Query: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPA-SLGTLL 120
ARWL+ + + GL+EL + A +G +DTLT E+L S M++EL Q SL +L
Sbjct: 283 ARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEML 342
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
MP + R + + FA +FGL L +Q LG+N+FLLQ G V + A A L
Sbjct: 343 HMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALK 402
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
++ RR + + L +C+LA VP EM LR LA LGLG A T + +E+ P
Sbjct: 403 YMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIP 462
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSL 300
T++R A+G+ A L PL+ +L V+ P LP ++YG P +SG A LLLPET++
Sbjct: 463 TIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNK 522
Query: 301 PLPDTIQDVQNQ 312
PL DTIQD +N+
Sbjct: 523 PLFDTIQDEKNE 534
>gi|166064021 solute carrier family 22 (organic anion transporter),
member 13 [Homo sapiens]
Length = 551
Score = 211 bits (538), Expect = 6e-55
Identities = 115/309 (37%), Positives = 177/309 (57%), Gaps = 8/309 (2%)
Query: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
EW R + L FS G + A +AYG R+W LLQ+ + P L F Y W L ES
Sbjct: 215 EWVGPSWRTQAVVLAQCNFSLGQMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPES 274
Query: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLR 121
ARWLLT GR+D +Q + + A++N + L+PE++ + E+ P + L R
Sbjct: 275 ARWLLTRGRMDEAIQLIQKAASVNRR-----KLSPELMNQLVPEKTG---PSGNALDLFR 326
Query: 122 MPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH 181
P LR T I WF ++GL+L + G +++L Q+ G V++PA+ ++ ++
Sbjct: 327 HPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQR 386
Query: 182 LGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPT 241
GR+ + +L+L GL + +P ++ + + LAV+G AAFT +YS+ELFPT
Sbjct: 387 FGRKWSQLGTLVLGGLMCIIIIFIPADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPT 446
Query: 242 VLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLP 301
+LR T +GL + +R G IL PLV LLG + LP+L+YG++P+++GL LLPET
Sbjct: 447 ILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQG 506
Query: 302 LPDTIQDVQ 310
L DT+QD++
Sbjct: 507 LKDTLQDLE 515
Score = 33.5 bits (75), Expect = 0.27
Identities = 44/144 (30%), Positives = 62/144 (43%), Gaps = 14/144 (9%)
Query: 178 LLSHLGRRPTLAASLLLAGLCILANTLVP--HEMGALRSALAVLGLGGVGAAFTCITIYS 235
L +GR+ T+ A LLL L LA VP ALR A+A G +F+ +T+ +
Sbjct: 158 LCDRIGRKATILAQLLLFTLIGLATAFVPSFELYMALRFAVAT---AVAGLSFSNVTLLT 214
Query: 236 SELFPT------VLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGL 289
+ P+ VL LGQM G A RLL + G LL++ L
Sbjct: 215 EWVGPSWRTQAVVLAQCNFSLGQMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPES 274
Query: 290 AALLLPETQSLPLPDTIQDVQNQA 313
A LL + + + IQ +Q A
Sbjct: 275 ARWLLTRGR---MDEAIQLIQKAA 295
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 197 bits (500), Expect = 1e-50
Identities = 118/315 (37%), Positives = 172/315 (54%), Gaps = 6/315 (1%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW R + L+S ++ G L A V Y +RDW L L V++P L WW+ E
Sbjct: 221 LEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPE 280
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARWLLT G + + L A +NG+ +D+ + E + E + +P S L
Sbjct: 281 SARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRP--SYLDLF 338
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R P LR + + WF F+++GL+LD+ LG N++ Q+ G V++P+K+ L +
Sbjct: 339 RTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVR 398
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
+ GRR T A +LL L LV +M + + LAV+G AAFT +++SEL+P
Sbjct: 399 YAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYP 458
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPW--LPLLVYGTVPVLSGLAALLLPETQ 298
TVLR T +GL + R G L PL LL G W LP L YG + +L+ ALLLPET+
Sbjct: 459 TVLRQTGMGLTALVGRLGGSLAPLAALL--DGVWLSLPKLTYGGIALLAAGTALLLPETR 516
Query: 299 SLPLPDTIQDVQNQA 313
LP+TIQDV+ ++
Sbjct: 517 QAQLPETIQDVERKS 531
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 197 bits (500), Expect = 1e-50
Identities = 118/315 (37%), Positives = 172/315 (54%), Gaps = 6/315 (1%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAE 60
+EW R + L+S ++ G L A V Y +RDW L L V++P L WW+ E
Sbjct: 219 LEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPE 278
Query: 61 SARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLL 120
SARWLLT G + + L A +NG+ +D+ + E + E + +P S L
Sbjct: 279 SARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRP--SYLDLF 336
Query: 121 RMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLS 180
R P LR + + WF F+++GL+LD+ LG N++ Q+ G V++P+K+ L +
Sbjct: 337 RTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVR 396
Query: 181 HLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFP 240
+ GRR T A +LL L LV +M + + LAV+G AAFT +++SEL+P
Sbjct: 397 YAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYP 456
Query: 241 TVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPW--LPLLVYGTVPVLSGLAALLLPETQ 298
TVLR T +GL + R G L PL LL G W LP L YG + +L+ ALLLPET+
Sbjct: 457 TVLRQTGMGLTALVGRLGGSLAPLAALL--DGVWLSLPKLTYGGIALLAAGTALLLPETR 514
Query: 299 SLPLPDTIQDVQNQA 313
LP+TIQDV+ ++
Sbjct: 515 QAQLPETIQDVERKS 529
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 173 bits (439), Expect = 2e-43
Identities = 108/325 (33%), Positives = 173/325 (53%), Gaps = 18/325 (5%)
Query: 20 FSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELW 79
++FG+ + AY +RDW +L + +++P LC W++ ES RWL++ GR + +
Sbjct: 239 YAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIR 298
Query: 80 RVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAF 139
+ A NG P S +++ S Q ++ LLR +R T +S + W
Sbjct: 299 KAAKANGIVVPSTIFDP----SELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTI 354
Query: 140 GFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCI 199
+FGL+LD L +IF+ +V++PA + A LLL +L RR ++A +L L G +
Sbjct: 355 SVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVL 414
Query: 200 LANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGA 259
L LVP ++ L + L ++G GV AAF+ + +Y++EL+PTV+R VG+ A+R G+
Sbjct: 415 LFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGS 474
Query: 260 ILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVKKATH 319
IL P LG + +LP ++ G++ +L+ + L LPE+ PLPDTI Q VK H
Sbjct: 475 ILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTID--QMLRVKGMKH 532
Query: 320 ------------GTLGNSVLKSTQF 332
G ++LKST F
Sbjct: 533 RKTPSHTRMLKDGQERPTILKSTAF 557
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 162 bits (410), Expect = 4e-40
Identities = 102/314 (32%), Positives = 163/314 (51%), Gaps = 17/314 (5%)
Query: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
E ++ R +V + + F+ G + +AY + +W +QL +++P FL LY W + ES
Sbjct: 232 EIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPES 291
Query: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGT--- 118
RWL+T + D LQ L R+A NGK LS+ E+++ S +
Sbjct: 292 PRWLITRKKGDKALQILRRIAKCNGK-----------YLSSNYSEITVTDEEVSNPSFLD 340
Query: 119 LLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLL 178
L+R P +R T I WF + GL + L +G N+++ GVV++P + LL
Sbjct: 341 LVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLT 400
Query: 179 LSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSEL 238
+ LGRR AAS ++AG+ L +P + LR+ +A LG G+ AF + + +SEL
Sbjct: 401 IERLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSEL 460
Query: 239 FPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPW--LPLLVYGTVPVLSGLAALLLPE 296
+PT LR V L G I+ P + L + W LPL+++G + + G +LLPE
Sbjct: 461 YPTTLRNFGVSLCSGLCDFGGIIAPFL-LFRLAAVWLELPLIIFGILASICGGLVMLLPE 519
Query: 297 TQSLPLPDTIQDVQ 310
T+ + LP+T+ DV+
Sbjct: 520 TKGIALPETVDDVE 533
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 155 bits (393), Expect = 4e-38
Identities = 94/291 (32%), Positives = 153/291 (52%), Gaps = 6/291 (2%)
Query: 20 FSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELW 79
F+ G+ L AY +RDW +L L ++VP LC W++ ES RWL++ R +
Sbjct: 239 FAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQ 298
Query: 80 RVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAF 139
+ A +N + P V+ ++ E + Q A + L R + T +S L W
Sbjct: 299 KAAKMN------NIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLT 352
Query: 140 GFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCI 199
+F L+LD L + +L +++IPA + A LLL L RR +AA L G +
Sbjct: 353 SVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGGGVL 412
Query: 200 LANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGA 259
L LVP + L L +LG G+ +AF+ + ++++EL+PT++R AVG+ A+R G+
Sbjct: 413 LFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGS 472
Query: 260 ILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQ 310
I+ P LG + LP +V G++ VL G+ L PE+ + LP+T++ +Q
Sbjct: 473 IIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQ 523
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 146 bits (368), Expect = 3e-35
Identities = 95/314 (30%), Positives = 159/314 (50%), Gaps = 13/314 (4%)
Query: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
E+ R R V + ++ G + A VAY + W LQ V++P F LY W + ES
Sbjct: 227 EFVGRRYRRTVGIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPES 286
Query: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLR 121
RWL++ + ++ + +A NGK +L + + EE P+ L L+R
Sbjct: 287 PRWLISQNKNAEAMRIIKHIAKKNGK-----SLPASLQRLRLEEETGKKLNPSFLD-LVR 340
Query: 122 MPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH 181
P +R T I WF + GL + + G NI+L + +V+ PA +L +
Sbjct: 341 TPQIRKHTMILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDR 400
Query: 182 LGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPT 241
+GRR AAS ++AG LA+ +P ++ L+ ++ LG G+ A+ + + ++EL+PT
Sbjct: 401 IGRRYPWAASNMVAGAACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPT 460
Query: 242 VLRMTAVGLGQMAARGGAILGPLV--RLLGVHGPW--LPLLVYGTVPVLSGLAALLLPET 297
+R V + G I+ P + RL + W LPL+V+G + +++G LLLPET
Sbjct: 461 FIRNLGVHICSSMCDIGGIITPFLVYRLTNI---WLELPLMVFGVLGLVAGGLVLLLPET 517
Query: 298 QSLPLPDTIQDVQN 311
+ LP+TI++ +N
Sbjct: 518 KGKALPETIEEAEN 531
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 141 bits (356), Expect = 7e-34
Identities = 96/312 (30%), Positives = 152/312 (48%), Gaps = 9/312 (2%)
Query: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
E+ + +R V + + F+ G +AY + W LQL VS+P FL LY W + ES
Sbjct: 226 EFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPES 285
Query: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLR 121
RWLL+ R ++ + +A NGK L P L EE + S L R
Sbjct: 286 PRWLLSQKRNTEAIKIMDHIAQKNGK------LPPADLKMLSLEEDVTEKLSPSFADLFR 339
Query: 122 MPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH 181
P LR RT I WF + GL L + A N++L ++ +V+IP AL+ +
Sbjct: 340 TPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDR 399
Query: 182 LGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPT 241
+GR +A S LLAG L + ++ L + +G G+ A I + ++EL+PT
Sbjct: 400 VGRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPT 459
Query: 242 VLRMTAVGLGQMAARGGAILGPLVRLLGVHGPW--LPLLVYGTVPVLSGLAALLLPETQS 299
+R V + G I+ P + + + W LPL+++ + +L+ LLLPET+
Sbjct: 460 FVRNLGVMVCSSLCDIGGIITPFI-VFRLREVWQALPLILFAVLGLLAAGVTLLLPETKG 518
Query: 300 LPLPDTIQDVQN 311
+ LP+T++D +N
Sbjct: 519 VALPETMKDAEN 530
>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
Length = 547
Score = 137 bits (346), Expect = 1e-32
Identities = 101/329 (30%), Positives = 157/329 (47%), Gaps = 16/329 (4%)
Query: 11 LVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGR 70
L ++ L F+ G A + Y +R W L ++V++ + FL S ++ ES RWL + GR
Sbjct: 198 LAGSIGGLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGR 257
Query: 71 LDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTC 130
L + L+ +A N K +LT S + S L R L T
Sbjct: 258 LSEAEEALYLIAKRNRKLKCTFSLTHPANRSC--------RETGSFLDLFRYRVLLGHTL 309
Query: 131 ISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH--LGRRPTL 188
I WF ++GL L LG +I+ G+++IP+ + L++ GR+ TL
Sbjct: 310 ILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTL 369
Query: 189 AASLLLAGLCILANTLVPHE-----MGALRS-ALAVLGLGGVGAAFTCITIYSSELFPTV 242
+A L L GL L +P + + S +L++LG + AAF + IY+SEL+PTV
Sbjct: 370 SAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTV 429
Query: 243 LRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPL 302
+R +G M +R G I+ P + L LP +V+G + SGL +LLLPET + PL
Sbjct: 430 IRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETLNSPL 489
Query: 303 PDTIQDVQNQAVKKATHGTLGNSVLKSTQ 331
+T D+Q + ++ L L Q
Sbjct: 490 LETFSDLQVYSYRRLGEEALSLQALDPQQ 518
>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
Length = 577
Score = 132 bits (333), Expect = 3e-31
Identities = 107/348 (30%), Positives = 161/348 (46%), Gaps = 29/348 (8%)
Query: 1 MEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVS---VPFFLCFLYSWW 57
ME+ ++R F+ G L A Y VR W L Q+++S VPF LC W
Sbjct: 231 MEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILC---CWV 287
Query: 58 LAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLG 117
L E+ WLL+ GR + E ++ I K + LLS L + P ++
Sbjct: 288 LPETPFWLLSEGRYE----EAQKIVDIMAKWNRASSCKLSELLS-----LDLQGPVSNSP 338
Query: 118 TLLRMPGLRF---------RTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVD 168
T ++ L + RT L WF F+ +L+ LG N +L +GVV+
Sbjct: 339 TEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVE 398
Query: 169 IPAKMGALLLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAF 228
IPA + + +GRR LA SL + L ++P + L A++G +GAAF
Sbjct: 399 IPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAF 458
Query: 229 TCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSG 288
I +Y++EL+PT++R AVG G M R +IL P L ++P L GT+ +LSG
Sbjct: 459 GLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSG 518
Query: 289 LAALLLPETQSLPLPDTIQDV-----QNQAVKKATHGTLGNSVLKSTQ 331
+ L LPET L T ++ +N++ T NS L+ T+
Sbjct: 519 VLTLKLPETLGKRLATTWEEAAKLESENESKSSKLLLTTNNSGLEKTE 566
>gi|157426885 organic cation transporter like 4 [Homo sapiens]
Length = 594
Score = 117 bits (292), Expect = 2e-26
Identities = 90/343 (26%), Positives = 161/343 (46%), Gaps = 27/343 (7%)
Query: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
EW R + L F+ G L +AY + W LL LV + Y W L ES
Sbjct: 261 EWLVGEHRAHAIILGHCFFAVGAVLLTGIAYSLPHWQLLFLVGGILVIPFISYIWILPES 320
Query: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLR 121
RWL+ G++ Q L A++N K + L E+ L R++++ AS+ +
Sbjct: 321 PRWLMMKGKVKEAKQVLCYAASVNKK-TIPSNLLDELQLP--RKKVTR----ASVLDFCK 373
Query: 122 MPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH 181
L T + + WF +T+F L+L ++ LG ++ + ++++PA++ + LL
Sbjct: 374 NRQLCKVTLVMSCVWFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQ 433
Query: 182 LGRRPTLAASLLLAGLCILANTLVPH---------------EMGALRSALAVLGLGGVGA 226
+GR+ +LA +LL A + L +P E+ ++ + +L + A
Sbjct: 434 IGRKWSLAVTLLQAIIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAA 493
Query: 227 AFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVL 286
T +Y++EL PTVLR T +GL +A+ GAIL + ++ LP+ + + ++
Sbjct: 494 TVTVFFLYTAELLPTVLRATGLGLVSLASVAGAILS--LTIISQTPSLLPIFLCCVLAIV 551
Query: 287 SGLAALLLPETQSLPLPDTI---QDVQNQAVKKATHGTLGNSV 326
+ + LLPET+ PL +++ ++N+ T T + V
Sbjct: 552 AFSLSSLLPETRDQPLSESLNHSSQIRNKVKDMKTKETSSDDV 594
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 110 bits (275), Expect = 2e-24
Identities = 75/240 (31%), Positives = 113/240 (47%), Gaps = 6/240 (2%)
Query: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
E+ + +R V + + F+ G +AY + W LQL VS+P FL LY W + ES
Sbjct: 226 EFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPES 285
Query: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLR 121
RWLL+ R ++ + +A NGK L P L EE + S L R
Sbjct: 286 PRWLLSQKRNTEAIKIMDHIAQKNGK------LPPADLKMLSLEEDVTEKLSPSFADLFR 339
Query: 122 MPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH 181
P LR RT I WF + GL L + A N++L ++ +V+IP AL+ +
Sbjct: 340 TPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDR 399
Query: 182 LGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPT 241
+GR +A S LLAG L + ++ L + +G G+ A I + ++EL+PT
Sbjct: 400 VGRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPT 459
>gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1
[Homo sapiens]
Length = 558
Score = 89.7 bits (221), Expect = 3e-18
Identities = 95/315 (30%), Positives = 145/315 (46%), Gaps = 32/315 (10%)
Query: 18 LGFSFGHGLTAAV--------AYGVRDWTLLQLVVSVPFFLCFLYSWWLA---ESARWLL 66
L FS G GL + V A V+DW LLQ + ++ L L+ + A ES WLL
Sbjct: 215 LAFSMGAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLL 274
Query: 67 TTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPP-----ASLGTLLR 121
TG++ + LWR A +G G +L L +A + + P + LG L
Sbjct: 275 ATGQVARARKILWRFAEASGVGPGDSSLEENSLATATELTMLSARSPQPRYHSPLGLL-- 332
Query: 122 MPGLRFRTCISTLCWFAFGFTFF---GLALDLQ-ALGSNI--FLLQMFIGV-VDIPAKMG 174
RT ++ GF+ G+ + +L + F L F+ ++ A +
Sbjct: 333 ------RTRVTWRNGLILGFSSLVGGGIRASFRRSLAPQVPTFYLPYFLEAGLEAAALVF 386
Query: 175 ALLLLSHLGRRPTLAASLLLAGLC-ILANTLVPHEMGALRSALAVLGLGGVGAAFTCITI 233
LL GRRP L ++ GL +L + G L+VLGL A ++
Sbjct: 387 LLLTADCCGRRPVLLLGTMVTGLASLLLLAGAQYLPGWTVLFLSVLGLLASRAVSALSSL 446
Query: 234 YSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALL 293
+++E+FPTV+R +GL A G GPL L G G +L +V+ ++ VL+ L LL
Sbjct: 447 FAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLL 506
Query: 294 LPETQSLPLPDTIQD 308
LPE++S LP ++QD
Sbjct: 507 LPESRSRGLPQSLQD 521
>gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6
[Homo sapiens]
Length = 560
Score = 85.9 bits (211), Expect = 5e-17
Identities = 94/315 (29%), Positives = 144/315 (45%), Gaps = 32/315 (10%)
Query: 18 LGFSFGHGLTAAV--------AYGVRDWTLLQLVVSVPFFLCFLYSWWLA---ESARWLL 66
L FS G GL + V A V+DW LLQ + ++ L L+ + A ES WLL
Sbjct: 217 LAFSMGAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLL 276
Query: 67 TTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPP-----ASLGTLLR 121
TG++ + LWR A +G G +L L +A + + P + LG L
Sbjct: 277 ATGQVARARKILWRFAEASGVGPGDSSLEENSLATATELTMLSARSPQPRYHSPLGLL-- 334
Query: 122 MPGLRFRTCISTLCWFAFGFTFF---GLALDLQ-ALGSNI--FLLQMFIGV-VDIPAKMG 174
RT ++ GF+ G+ + +L + F L F+ ++ A +
Sbjct: 335 ------RTRVTWRNGLILGFSSLVGGGIRASFRRSLAPQVPTFYLPYFLEAGLEAAALVF 388
Query: 175 ALLLLSHLGRRPTLAASLLLAGLC-ILANTLVPHEMGALRSALAVLGLGGVGAAFTCITI 233
LL GRRP L ++ GL +L + G L+VLGL A ++
Sbjct: 389 LLLTADCCGRRPVLLLGTMVTGLASLLLLAGAQYLPGWTVLFLSVLGLLASRAVSALSSL 448
Query: 234 YSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALL 293
+++E+FPTV+R +GL A G G L L G G +L +V+ ++ VL+ L LL
Sbjct: 449 FAAEVFPTVIRGAGLGLVLGAGFLGQAAGLLDTLHGRQGFFLQQVVFASLAVLALLCVLL 508
Query: 294 LPETQSLPLPDTIQD 308
LPE++S LP ++QD
Sbjct: 509 LPESRSRGLPQSLQD 523
>gi|63999576 solute carrier family 22, member 17 isoform b [Homo
sapiens]
Length = 520
Score = 75.9 bits (185), Expect = 5e-14
Identities = 79/296 (26%), Positives = 128/296 (43%), Gaps = 15/296 (5%)
Query: 23 GHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSW--WLAESARWLLTTGRLDWGLQELWR 80
GH L +A +DW LQ +++ P L Y W ESARWL+ +++ Q + R
Sbjct: 199 GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEA-QSVLR 257
Query: 81 VAAINGKGAVQDTLTPEVLLSAMRE-ELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAF 139
+ A + Q + E A+++ E + P S + + L +R L F
Sbjct: 258 ILAERNRPHGQ--MLGEEAQEALQDLENTCPLPATSSFSFASL--LNYRNIWKNLLILGF 313
Query: 140 -GFTFFGLALDLQALG-----SNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLL 193
F + Q +G S+ +L + A + + + GRR L S+
Sbjct: 314 TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMT 373
Query: 194 LAGLCILANT-LVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQ 252
L G+ L L + A + +VLGL AA T+ ++E+ PT +R +GL
Sbjct: 374 LTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLIM 433
Query: 253 MAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQD 308
G + GP RL HG +L +V +L L+ +LLPET+ LP+ ++D
Sbjct: 434 ALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRD 489
>gi|21361834 solute carrier family 22, member 17 isoform a [Homo
sapiens]
Length = 538
Score = 72.4 bits (176), Expect = 5e-13
Identities = 87/318 (27%), Positives = 135/318 (42%), Gaps = 41/318 (12%)
Query: 23 GHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSW--WLAESARWLLTTGRLDWGLQELWR 80
GH L +A +DW LQ +++ P L Y W ESARWL+ +++ Q + R
Sbjct: 199 GHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEA-QSVLR 257
Query: 81 VAAINGKGAVQDTLTPEVLLSAMRE-ELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAF 139
+ A + Q + E A+++ E + P S + + L +R L F
Sbjct: 258 ILAERNRPHGQ--MLGEEAQEALQDLENTCPLPATSSFSFASL--LNYRNIWKNLLILGF 313
Query: 140 -GFTFFGLALDLQALG-----SNIFLLQM-----------FIGV-VDIPAKMGALLLLSH 181
F + Q +G S+ +L + F+GV VD + G LLL
Sbjct: 314 TNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLSMT 373
Query: 182 LGRRPTLAASLLLAGLCILANTLVPHEMG-----------ALRSALAVLGLGGVGAAFTC 230
L T ASL+L GL + + P A + +VLGL AA
Sbjct: 374 L----TGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAIL 429
Query: 231 ITIYSSELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLA 290
T+ ++E+ PT +R +GL G + GP RL HG +L +V +L L+
Sbjct: 430 STLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILS 489
Query: 291 ALLLPETQSLPLPDTIQD 308
+LLPET+ LP+ ++D
Sbjct: 490 IMLLPETKRKLLPEVLRD 507
>gi|24308167 SV2 related protein [Homo sapiens]
Length = 548
Score = 70.5 bits (171), Expect = 2e-12
Identities = 68/314 (21%), Positives = 130/314 (41%), Gaps = 44/314 (14%)
Query: 37 WTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTP 96
W L ++ +VP L + +WL ESAR+ + +G + + L R+A NG L
Sbjct: 237 WRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKL-- 294
Query: 97 EVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAFGFTFFGL---------- 146
++S + M L P R+ T + WF+ F+++GL
Sbjct: 295 --IISRQEDRGKMRD--------LFTPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQA 344
Query: 147 -----------------ALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLA 189
+L + L ++ ++ + + P + L ++ LGR+ T+A
Sbjct: 345 GDVCGISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMA 404
Query: 190 ASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVG 249
++ C L + + + L + + F +Y+ E++PT R +G
Sbjct: 405 LCFVIFSFCSLLLFICVGRN--VLTLLLFIARAFISGGFQAAYVYTPEVYPTATRALGLG 462
Query: 250 LGQMAARGGAILGPLV-RLLGVHGPWLPLLVYGTVPVLSGLAALLLP-ETQSLPLPDTI- 306
AR GA++ P + +++ +L L VY +L+ LA+ LP ET+ L ++
Sbjct: 463 TCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIETKGRGLQESSH 522
Query: 307 QDVQNQAVKKATHG 320
++ + V + HG
Sbjct: 523 REWGQEMVGRGMHG 536
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,618,333
Number of Sequences: 37866
Number of extensions: 482049
Number of successful extensions: 1645
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1539
Number of HSP's gapped (non-prelim): 79
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.