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Search of human proteins with 24497435
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens] 792 0.0
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens] 347 1e-95
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] 346 2e-95
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] 341 8e-94
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] 317 1e-86
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ... 316 3e-86
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens] 316 3e-86
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi... 310 2e-84
gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens] 281 6e-76
gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens] 281 6e-76
gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sap... 281 6e-76
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens] 213 2e-55
gi|6005942 valosin-containing protein [Homo sapiens] 202 4e-52
gi|157671927 spermatogenesis associated 5 [Homo sapiens] 193 2e-49
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] 190 2e-48
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens] 187 2e-47
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] 184 1e-46
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 182 4e-46
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] 182 4e-46
gi|4505725 peroxin1 [Homo sapiens] 177 1e-44
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 177 2e-44
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens] 169 5e-42
gi|5901990 katanin p60 subunit A 1 [Homo sapiens] 168 7e-42
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens] 167 2e-41
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens] 167 2e-41
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] 167 2e-41
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] 167 2e-41
gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive fa... 150 2e-36
gi|156564401 vesicle-fusing ATPase [Homo sapiens] 150 2e-36
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens] 145 5e-35
>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
Length = 406
Score = 792 bits (2046), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR 60
MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR
Sbjct: 1 MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLR 60
Query: 61 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS 120
EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS
Sbjct: 61 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS 120
Query: 121 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI 180
YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI
Sbjct: 121 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI 180
Query: 181 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE 240
AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE
Sbjct: 181 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE 240
Query: 241 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI 300
HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI
Sbjct: 241 HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI 300
Query: 301 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK 360
LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK
Sbjct: 301 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK 360
Query: 361 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK 406
GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK
Sbjct: 361 GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK 406
>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
Length = 433
Score = 347 bits (890), Expect = 1e-95
Identities = 174/309 (56%), Positives = 224/309 (72%)
Query: 84 KVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKV 143
K ++ V KFVVD+ + D+ RV + + Y +H LP K+DP V++M VE+
Sbjct: 110 KYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEK 169
Query: 144 PDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAV 203
PD TY +GG +QI++++EV+E P+ HPE F LGI PKGVLL+GPPGTGKTL ARAV
Sbjct: 170 PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAV 229
Query: 204 AHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGS 263
A+ TD FIRV GSELVQK++GEGARMVRELF MAR +IF DEID+IG +R + G+
Sbjct: 230 ANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGA 289
Query: 264 GGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEE 323
GGD+EVQRTMLEL+NQLDGF+ NIKV+MATNR D LD AL+RPGR+DRKIEF P+ E
Sbjct: 290 GGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLE 349
Query: 324 ARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDF 383
R I KIH+R M++ R I +A L P ++GAE++ VCTEAGM+A+R RR T++DF
Sbjct: 350 GRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDF 409
Query: 384 EMAVAKVMQ 392
AV KV++
Sbjct: 410 LEAVNKVIK 418
>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
Length = 440
Score = 346 bits (888), Expect = 2e-95
Identities = 180/377 (47%), Positives = 250/377 (66%), Gaps = 4/377 (1%)
Query: 20 LRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRA 79
L+ L +I++ L+ + +N Q Q L K R ++ L+ VG +
Sbjct: 60 LKLLKLERIKDYLLMEEEFIRN----QEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEI 115
Query: 80 MDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMM 139
+D +V + V + +D + + P C V L + + + +L + DPLV++M
Sbjct: 116 IDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMK 175
Query: 140 VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199
VEK P TY IGGLD QI+EIKE +ELP+ HPE +E +GI PKGV+LYGPPGTGKTLL
Sbjct: 176 VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLL 235
Query: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259
A+AVA+ T TF+RV GSEL+QK++G+G ++VRELF +A EHAPSI+F+DEID+IG+ R
Sbjct: 236 AKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRY 295
Query: 260 EGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPP 319
+ SGG+ E+QRTMLELLNQLDGF++ ++KVIMATNRI+ LD AL+RPGRIDRKIEFP
Sbjct: 296 DSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPL 355
Query: 320 PNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVT 379
P+E+ + I +IH+ +M L + L + SGA++K +CTEAG+ ALRERR+ VT
Sbjct: 356 PDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVT 415
Query: 380 QEDFEMAVAKVMQKDSE 396
EDF+ + V+ K E
Sbjct: 416 NEDFKKSKENVLYKKQE 432
>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
Length = 403
Score = 341 bits (874), Expect = 8e-94
Identities = 179/356 (50%), Positives = 240/356 (67%), Gaps = 2/356 (0%)
Query: 42 LRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDK 101
L+ L+ Q EL + +L+ LQ G VGEV++ + ++K +VK ++VV +
Sbjct: 40 LKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRR 99
Query: 102 NIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEI 161
+D + + P RVAL + T+ + LP +VDPLV M E + +Y IGGL +QI+E+
Sbjct: 100 QLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIREL 159
Query: 162 KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQ 221
+EVIELP+ +PELF+ +GI PKG LLYGPPGTGKTLLARAVA DC F++V S +V
Sbjct: 160 REVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVD 219
Query: 222 KFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLD 281
K+IGE AR++RE+F AR+H P IIFMDEID+IG R G+ D E+QRT++ELLNQ+D
Sbjct: 220 KYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMD 279
Query: 282 GFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRG 341
GF+ +K+IMATNR D LD ALLRPGR+DRKI PNE+ARLDILKIH+ +
Sbjct: 280 GFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGE 339
Query: 342 INLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEK 397
I+ I +L G +GA+++ VCTEAGM+A+R V QEDF AV KV DS+K
Sbjct: 340 IDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKV--ADSKK 393
>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
Length = 439
Score = 317 bits (812), Expect = 1e-86
Identities = 170/377 (45%), Positives = 237/377 (62%), Gaps = 4/377 (1%)
Query: 20 LRQYYLSKIEELQLIVNDKSQNLRRLQAQRNE---LNAKVRLLREELQLLQEQGSYVGEV 76
++ L ELQ + + +N +++ + ++ + LL + +E G+ + ++
Sbjct: 55 MKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANI-DL 113
Query: 77 VRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVS 136
K ++K + + V +D + P V + DSY + + LP + D V
Sbjct: 114 DSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVK 173
Query: 137 LMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGK 196
M V++ P Y IGGLDKQI+E+ E I LP+ H E FE LGI PKGVL+YGPPGTGK
Sbjct: 174 AMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGK 233
Query: 197 TLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGS 256
TLLARA A T TF++++G +LVQ FIG+GA++VR+ F +A+E APSIIF+DE+D+IG+
Sbjct: 234 TLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGT 293
Query: 257 SRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIE 316
R + GD EVQRTMLELLNQLDGF+ +KVI ATNR+DILD ALLR GR+DRKIE
Sbjct: 294 KRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIE 353
Query: 317 FPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRV 376
FP PNEEAR I++IHSRKMN++ +N ++A +GA+ K VC EAGM ALR
Sbjct: 354 FPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGAT 413
Query: 377 HVTQEDFEMAVAKVMQK 393
+T ED+ + +V K
Sbjct: 414 ELTHEDYMEGILEVQAK 430
>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
[Homo sapiens]
Length = 414
Score = 316 bits (809), Expect = 3e-86
Identities = 170/396 (42%), Positives = 247/396 (62%), Gaps = 14/396 (3%)
Query: 5 GPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRR--LQAQRNELNAKVRLLREE 62
GPE +LE+ + Q L +E + + D+ +NL++ L AQ EE
Sbjct: 27 GPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQ------------EE 74
Query: 63 LQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYT 122
++ +Q +G+ + A+D+ +V + V + ID + PN VAL S
Sbjct: 75 VKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNA 134
Query: 123 LHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQ 182
L +LP + D + ++ ++ PD Y IGG+D Q +E++E +ELP+ H EL++ +GI
Sbjct: 135 LVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDP 194
Query: 183 PKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 242
P+GVL+YGPPG GKT+LA+AVAHHT FIRV GSE VQK++GEG RMVR++F +A+E+A
Sbjct: 195 PRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENA 254
Query: 243 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILD 302
P+IIF+DEID+I + R + +G D EVQR +LELLNQ+DGF+ N+KVIMATNR D LD
Sbjct: 255 PAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLD 314
Query: 303 SALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGV 362
ALLRPGR+DRKIEFP P+ + I + KMNL+ ++L SGA++ +
Sbjct: 315 PALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSI 374
Query: 363 CTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKN 398
C E+GM A+RE R V +DFE A V++KD +++
Sbjct: 375 CQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEH 410
>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
Length = 418
Score = 316 bits (809), Expect = 3e-86
Identities = 170/396 (42%), Positives = 247/396 (62%), Gaps = 14/396 (3%)
Query: 5 GPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRR--LQAQRNELNAKVRLLREE 62
GPE +LE+ + Q L +E + + D+ +NL++ L AQ EE
Sbjct: 31 GPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQ------------EE 78
Query: 63 LQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYT 122
++ +Q +G+ + A+D+ +V + V + ID + PN VAL S
Sbjct: 79 VKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNA 138
Query: 123 LHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQ 182
L +LP + D + ++ ++ PD Y IGG+D Q +E++E +ELP+ H EL++ +GI
Sbjct: 139 LVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDP 198
Query: 183 PKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 242
P+GVL+YGPPG GKT+LA+AVAHHT FIRV GSE VQK++GEG RMVR++F +A+E+A
Sbjct: 199 PRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENA 258
Query: 243 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILD 302
P+IIF+DEID+I + R + +G D EVQR +LELLNQ+DGF+ N+KVIMATNR D LD
Sbjct: 259 PAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLD 318
Query: 303 SALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGV 362
ALLRPGR+DRKIEFP P+ + I + KMNL+ ++L SGA++ +
Sbjct: 319 PALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSI 378
Query: 363 CTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKN 398
C E+GM A+RE R V +DFE A V++KD +++
Sbjct: 379 CQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEH 414
>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
sapiens]
Length = 387
Score = 310 bits (793), Expect = 2e-84
Identities = 161/366 (43%), Positives = 232/366 (63%)
Query: 33 LIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPE 92
L V+ L L + +L +EE++ +Q +G+ + A+D+ +V
Sbjct: 18 LSVSRPQTGLSFLGPEPEDLEDLYSRYKEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTG 77
Query: 93 GKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIG 152
+ V + ID + PN VAL S L +LP + D + ++ ++ PD Y IG
Sbjct: 78 SNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIG 137
Query: 153 GLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFI 212
G+D Q +E++E +ELP+ H EL++ +GI P+GVL+YGPPG GKT+LA+AVAHHT FI
Sbjct: 138 GMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFI 197
Query: 213 RVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRT 272
RV GSE VQK++GEG RMVR++F +A+E+AP+IIF+DEID+I + R + +G D EVQR
Sbjct: 198 RVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRI 257
Query: 273 MLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIH 332
+LELLNQ+DGF+ N+KVIMATNR D LD ALLRPGR+DRKIEFP P+ + I
Sbjct: 258 LLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTI 317
Query: 333 SRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQ 392
+ KMNL+ ++L SGA++ +C E+GM A+RE R V +DFE A V++
Sbjct: 318 TSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIK 377
Query: 393 KDSEKN 398
KD +++
Sbjct: 378 KDEQEH 383
>gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]
Length = 415
Score = 281 bits (720), Expect = 6e-76
Identities = 152/379 (40%), Positives = 230/379 (60%), Gaps = 20/379 (5%)
Query: 20 LRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRA 79
L+ L +I++ L+V + +N Q Q L K R ++ L+ VG +
Sbjct: 47 LKLLKLERIKDYLLMVEEFIRN----QEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEI 102
Query: 80 MDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMM 139
+D +V + + ++ + + P C + LR+ + + +L + PLV++M
Sbjct: 103 IDDNHAIVSTSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMK 162
Query: 140 VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199
VEK P TY GGLD QI+EIKE +ELP+ HPE +E +G PKGV+L GPPGT
Sbjct: 163 VEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA---- 218
Query: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259
TF+RV GSEL+QK++G+G ++VR++F +A EHAPSI+F DEI++IG+ R
Sbjct: 219 ----------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRY 268
Query: 260 EGGSGGDSEVQRTMLEL--LNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEF 317
+ SGG+ E+Q+TMLEL LNQL GF++ +++KVIMAT +++ LD L+RPGRID+KIEF
Sbjct: 269 DSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEF 328
Query: 318 PPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVH 377
P+E+ + I +IH+ +M L + L + SGA++K +CTEAG+ ALRE R+
Sbjct: 329 HLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMK 388
Query: 378 VTQEDFEMAVAKVMQKDSE 396
T EDF+ ++ V+ K E
Sbjct: 389 ATNEDFKKSIESVLYKKHE 407
>gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]
Length = 415
Score = 281 bits (720), Expect = 6e-76
Identities = 152/379 (40%), Positives = 230/379 (60%), Gaps = 20/379 (5%)
Query: 20 LRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRA 79
L+ L +I++ L+V + +N Q Q L K R ++ L+ VG +
Sbjct: 47 LKLLKLERIKDYLLMVEEFIRN----QEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEI 102
Query: 80 MDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMM 139
+D +V + + ++ + + P C + LR+ + + +L + PLV++M
Sbjct: 103 IDDNHAIVSTSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMK 162
Query: 140 VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199
VEK P TY GGLD QI+EIKE +ELP+ HPE +E +G PKGV+L GPPGT
Sbjct: 163 VEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA---- 218
Query: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259
TF+RV GSEL+QK++G+G ++VR++F +A EHAPSI+F DEI++IG+ R
Sbjct: 219 ----------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRY 268
Query: 260 EGGSGGDSEVQRTMLEL--LNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEF 317
+ SGG+ E+Q+TMLEL LNQL GF++ +++KVIMAT +++ LD L+RPGRID+KIEF
Sbjct: 269 DSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEF 328
Query: 318 PPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVH 377
P+E+ + I +IH+ +M L + L + SGA++K +CTEAG+ ALRE R+
Sbjct: 329 HLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMK 388
Query: 378 VTQEDFEMAVAKVMQKDSE 396
T EDF+ ++ V+ K E
Sbjct: 389 ATNEDFKKSIESVLYKKHE 407
>gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo
sapiens]
Length = 415
Score = 281 bits (720), Expect = 6e-76
Identities = 152/379 (40%), Positives = 230/379 (60%), Gaps = 20/379 (5%)
Query: 20 LRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRA 79
L+ L +I++ L+V + +N Q Q L K R ++ L+ VG +
Sbjct: 47 LKLLKLERIKDYLLMVEEFIRN----QEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEI 102
Query: 80 MDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMM 139
+D +V + + ++ + + P C + LR+ + + +L + PLV++M
Sbjct: 103 IDDNHAIVSTSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMK 162
Query: 140 VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199
VEK P TY GGLD QI+EIKE +ELP+ HPE +E +G PKGV+L GPPGT
Sbjct: 163 VEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA---- 218
Query: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259
TF+RV GSEL+QK++G+G ++VR++F +A EHAPSI+F DEI++IG+ R
Sbjct: 219 ----------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRY 268
Query: 260 EGGSGGDSEVQRTMLEL--LNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEF 317
+ SGG+ E+Q+TMLEL LNQL GF++ +++KVIMAT +++ LD L+RPGRID+KIEF
Sbjct: 269 DSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEF 328
Query: 318 PPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVH 377
P+E+ + I +IH+ +M L + L + SGA++K +CTEAG+ ALRE R+
Sbjct: 329 HLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMK 388
Query: 378 VTQEDFEMAVAKVMQKDSE 396
T EDF+ ++ V+ K E
Sbjct: 389 ATNEDFKKSIESVLYKKHE 407
>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
Length = 797
Score = 213 bits (542), Expect = 2e-55
Identities = 111/251 (44%), Positives = 158/251 (62%), Gaps = 5/251 (1%)
Query: 145 DSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVA 204
D ++ + G ++ EI E + +K+P+ ++ LG PKG +L GPPGTGKTLLA+A A
Sbjct: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
Query: 205 HHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSG 264
+ FI VSGSE ++ F+G G VR+LF +AR++AP I+F+DEID++G R G G
Sbjct: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
Query: 265 GDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEA 324
G SE + T+ +LL ++DGF T N+ ++ TNR DILD ALLRPGR DR+I PP+ +
Sbjct: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
Query: 325 RLDILKIHSRKMNLTRGIN----LRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQ 380
R I K+H R + L + RK+A L PG SGA+V VC EA + A R + Q
Sbjct: 483 RASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQ 542
Query: 381 EDFEMAVAKVM 391
+ FE A+ +V+
Sbjct: 543 KHFEQAIERVI 553
>gi|6005942 valosin-containing protein [Homo sapiens]
Length = 806
Score = 202 bits (514), Expect = 4e-52
Identities = 115/312 (36%), Positives = 184/312 (58%), Gaps = 10/312 (3%)
Query: 64 QLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTL 123
Q+ E +VG + A+ + L + + + D+ ID +V + V + + + L
Sbjct: 398 QVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDA-EVMNSLAVTMDDFRWAL 456
Query: 124 HKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQP 183
+ P+ + V +VP T+E IGGL+ +E++E+++ PV+HP+ F G+
Sbjct: 457 SQSNPSALRETVV-----EVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPS 511
Query: 184 KGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAP 243
KGVL YGPPG GKTLLA+A+A+ FI + G EL+ + GE VRE+F AR+ AP
Sbjct: 512 KGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAP 571
Query: 244 SIIFMDEIDSIGSSRLEGGSGGD--SEVQRTMLELLNQLDGFEATKNIKVIMATNRIDIL 301
++F DE+DSI +R GG+ GD R + ++L ++DG KN+ +I ATNR DI+
Sbjct: 572 CVLFFDELDSIAKAR--GGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDII 629
Query: 302 DSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKG 361
D A+LRPGR+D+ I P P+E++R+ ILK + RK + + ++L +A++ G SGA++
Sbjct: 630 DPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTE 689
Query: 362 VCTEAGMYALRE 373
+C A A+RE
Sbjct: 690 ICQRACKLAIRE 701
Score = 196 bits (497), Expect = 4e-50
Identities = 103/251 (41%), Positives = 166/251 (66%), Gaps = 4/251 (1%)
Query: 141 EKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLA 200
E + + Y+ IGG KQ+ +IKE++ELP++HP LF+A+G+ P+G+LLYGPPGTGKTL+A
Sbjct: 196 ESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIA 255
Query: 201 RAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLE 260
RAVA+ T F ++G E++ K GE +R+ F A ++AP+IIF+DE+D+I R +
Sbjct: 256 RAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREK 315
Query: 261 GGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPP 320
+ G+ E +R + +LL +DG + ++ V+ ATNR + +D AL R GR DR+++ P
Sbjct: 316 --THGEVE-RRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIP 372
Query: 321 NEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQ 380
+ RL+IL+IH++ M L ++L ++A G GA++ +C+EA + A+R++ +
Sbjct: 373 DATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDL 432
Query: 381 EDFEMAVAKVM 391
ED E A+VM
Sbjct: 433 ED-ETIDAEVM 442
>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
Length = 893
Score = 193 bits (491), Expect = 2e-49
Identities = 112/314 (35%), Positives = 177/314 (56%), Gaps = 12/314 (3%)
Query: 61 EELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS 120
E LQL YVG ++ + + L + + ++ N+ V ++ L++
Sbjct: 548 ELLQLANSAHGYVGADLKVLCNEAGLCAL----RRILKKQPNLPDVKVAGLVKITLKDFL 603
Query: 121 YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGI 180
++ I P+ + + VP+ ++ IGGL+ ++++ +E P+KHPE F +GI
Sbjct: 604 QAMNDIRPSAMREIAI-----DVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGI 658
Query: 181 AQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE 240
PKGVLLYGPPG KT++A+A+A+ + F+ + G EL+ K++GE R VRE F AR
Sbjct: 659 QPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARA 718
Query: 241 HAPSIIFMDEIDSIGSSRLEGGS-GGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRID 299
APSIIF DE+D++ R G S G + R + +LL ++DG E K++ ++ ATNR D
Sbjct: 719 VAPSIIFFDELDALAVER--GSSLGAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPD 776
Query: 300 ILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEV 359
+D AL+RPGRIDR I P P+ R +I K+ M ++ ++L ++ SGAE+
Sbjct: 777 RIDKALMRPGRIDRIIYVPLPDAATRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEI 836
Query: 360 KGVCTEAGMYALRE 373
VC EA + AL E
Sbjct: 837 VAVCREAALLALEE 850
Score = 186 bits (473), Expect = 3e-47
Identities = 106/231 (45%), Positives = 148/231 (64%), Gaps = 9/231 (3%)
Query: 147 TYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHH 206
TY+MIGGL Q+K I+E+IELP+K PELF++ GI P+GVLLYGPPGTGKT++ARAVA+
Sbjct: 351 TYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVANE 410
Query: 207 TDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGD 266
++G E++ KF GE +R++F A PSIIF+DE+D++ R G
Sbjct: 411 VGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKR----EGAQ 466
Query: 267 SEVQ-RTMLELLNQLDGFEATKN---IKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 322
+EV+ R + LL +DG + + + V+ ATNR LD+AL RPGR D++IE PN
Sbjct: 467 NEVEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNA 526
Query: 323 EARLDIL-KIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALR 372
+ RLDIL K+ R +L L ++A G GA++K +C EAG+ ALR
Sbjct: 527 QDRLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALR 577
>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
Length = 753
Score = 190 bits (483), Expect = 2e-48
Identities = 111/298 (37%), Positives = 175/298 (58%), Gaps = 26/298 (8%)
Query: 126 ILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKG 185
I P+ ++ LM ++ V +E IGGL+ ++K+ IE P+K P F +G+ QPKG
Sbjct: 444 IQPSSFRSVIGLMDIKPVD---WEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKG 500
Query: 186 VLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSI 245
VLLYGPPG KT L RA+A C+F+ VSG++L F+G+ +++ ++F AR P+I
Sbjct: 501 VLLYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAI 560
Query: 246 IFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEA-------------------T 286
+F+DEIDSI +R +G D + +R + LLN+LDG
Sbjct: 561 LFLDEIDSILGARSASKTGCDVQ-ERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFN 619
Query: 287 KNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRK 346
+++ +I ATNR D+LD+ALLRPGR+D+ I PPP+ + RL ILK+ ++ M + ++L
Sbjct: 620 RSVMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLEN 679
Query: 347 IAELMPGASGAEVKGVCTEAGMYALRERRVHVT---QEDFEMAVAKVMQKDSEKNMSI 401
+A SGA+++ +CTEA + AL+E + T QE F ++ V S K++++
Sbjct: 680 LAAETCFFSGADLRNLCTEAALLALQENGLDATTVKQEHFLKSLKTVKPSLSCKDLAL 737
Score = 155 bits (391), Expect = 8e-38
Identities = 97/267 (36%), Positives = 145/267 (54%), Gaps = 27/267 (10%)
Query: 108 VTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIEL 167
VTP RV+L + P++ P +VP +GGL + ++E++ L
Sbjct: 178 VTPRTRVSLGGEP-------PSEAQPQ------PEVP------LGGLSEAADSLRELLRL 218
Query: 168 PVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEG 227
P+++P ALG+A P+GVLL GPPG GKT L RAVA + VS L GE
Sbjct: 219 PLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAELLAVSAPALQGSRPGET 278
Query: 228 ARMVRELFVMAREHA---PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFE 284
VR +F ARE A PS++F+DE+D++ R G + R + ++L LDG
Sbjct: 279 EENVRRVFQRARELASRGPSLLFLDEMDALCPQR-----GSRAPESRVVAQVLTLLDGAS 333
Query: 285 ATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINL 344
+ + V+ ATNR D LD AL RPGR DR++ P + R +IL++ + KM ++ ++L
Sbjct: 334 GDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKEILQVITSKMPISSHVDL 393
Query: 345 RKIAELMPGASGAEVKGVCTEAGMYAL 371
+AE+ G GA++ +C EA M+AL
Sbjct: 394 GLLAEMTVGYVGADLTALCREAAMHAL 420
>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
Length = 795
Score = 187 bits (474), Expect = 2e-47
Identities = 102/260 (39%), Positives = 159/260 (61%), Gaps = 4/260 (1%)
Query: 147 TYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHH 206
+++ + G+ + E++E ++ +K PE F LG PKG LL GPPG GKTLLA+AVA
Sbjct: 307 SFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365
Query: 207 TDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSG-G 265
F+ ++G E V+ G GA VR LF AR AP I+++DEID++G R SG
Sbjct: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425
Query: 266 DSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEAR 325
++E ++T+ +LL ++DG T ++ V+ +TNR DILD AL+RPGR+DR + P + R
Sbjct: 426 NTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQER 485
Query: 326 LDILKIHSRKMNLTRGINL--RKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDF 383
+I + H + + LT+ +++AEL PG SGA++ +C EA ++A RE V +F
Sbjct: 486 REIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLNF 545
Query: 384 EMAVAKVMQKDSEKNMSIKK 403
E AV +V+ ++K+ + K
Sbjct: 546 EYAVERVLAGTAKKSKILSK 565
>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
Length = 980
Score = 184 bits (467), Expect = 1e-46
Identities = 109/253 (43%), Positives = 160/253 (63%), Gaps = 8/253 (3%)
Query: 142 KVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLAR 201
K+P ++ +GGL + KEI E I+LP++HPEL +LG+ + G+LL+GPPGTGKTLLA+
Sbjct: 698 KIPSVSWHDVGGLQEVKKEILETIQLPLEHPELL-SLGLRR-SGLLLHGPPGTGKTLLAK 755
Query: 202 AVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEG 261
AVA TF+ V G EL+ ++G+ VRE+F AR AP IIF DE+DS+ SR
Sbjct: 756 AVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRS 815
Query: 262 GSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPN 321
G G + R + +LL +LDG +T+++ VI ATNR D+LD ALLRPGR D K+ F N
Sbjct: 816 GDSG-GVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFD-KLVFVGAN 873
Query: 322 EE--ARLDILKIHSRKMNLTRGINLRKIAELM-PGASGAEVKGVCTEAGMYALRERRVHV 378
E+ ++L +L +RK L ++L + + P +GA++ +C++A M A +RRVH
Sbjct: 874 EDRASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDA-MTAALKRRVHD 932
Query: 379 TQEDFEMAVAKVM 391
+E E + +M
Sbjct: 933 LEEGLEPGSSALM 945
Score = 66.6 bits (161), Expect = 4e-11
Identities = 48/185 (25%), Positives = 83/185 (44%), Gaps = 4/185 (2%)
Query: 186 VLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSI 245
VLL GPPG GKT + A H ++V S L + G ++ +F AR P++
Sbjct: 466 VLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAV 525
Query: 246 IFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSAL 305
+ + +D +G R G G D+ V + LL D + + V+ T+R L + +
Sbjct: 526 LLLTAVDLLGRDR--DGLGEDARVMAVLRHLLLNEDPLNSCPPLMVVATTSRAQDLPADV 583
Query: 306 LRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTE 365
++E P +E RL IL+ + + L + +NL ++A G ++ + T
Sbjct: 584 --QTAFPHELEVPALSEGQRLSILRALTAHLPLGQEVNLAQLARRCAGFVVGDLYALLTH 641
Query: 366 AGMYA 370
+ A
Sbjct: 642 SSRAA 646
>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
Length = 773
Score = 182 bits (463), Expect = 4e-46
Identities = 102/275 (37%), Positives = 168/275 (61%), Gaps = 10/275 (3%)
Query: 127 LPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGV 186
L + VDP+ ++ + T+E + G+++ +E++EV+E +K+P+ F LG PKG+
Sbjct: 324 LDSAVDPV-------QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGI 375
Query: 187 LLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSII 246
LL GPPGTGKTLLARAVA D F SGSE + F+G GA +R LF A+ +AP +I
Sbjct: 376 LLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVI 435
Query: 247 FMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALL 306
F+DE+DS+G R+E S ++T+ +LL ++DGF+ + + +I ATN + LD+AL+
Sbjct: 436 FIDELDSVGGKRIESPMHPYS--RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALI 493
Query: 307 RPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEA 366
RPGR D ++ P P+ + R +ILK + K+ + ++ IA G SGAE++ + +A
Sbjct: 494 RPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQA 553
Query: 367 GMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSI 401
+ A + + VT ++ E + K++ +++ I
Sbjct: 554 ALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEI 588
>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
Length = 716
Score = 182 bits (463), Expect = 4e-46
Identities = 102/275 (37%), Positives = 168/275 (61%), Gaps = 10/275 (3%)
Query: 127 LPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGV 186
L + VDP+ ++ + T+E + G+++ +E++EV+E +K+P+ F LG PKG+
Sbjct: 267 LDSAVDPV-------QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGI 318
Query: 187 LLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSII 246
LL GPPGTGKTLLARAVA D F SGSE + F+G GA +R LF A+ +AP +I
Sbjct: 319 LLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVI 378
Query: 247 FMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALL 306
F+DE+DS+G R+E S ++T+ +LL ++DGF+ + + +I ATN + LD+AL+
Sbjct: 379 FIDELDSVGGKRIESPMHPYS--RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALI 436
Query: 307 RPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEA 366
RPGR D ++ P P+ + R +ILK + K+ + ++ IA G SGAE++ + +A
Sbjct: 437 RPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQA 496
Query: 367 GMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSI 401
+ A + + VT ++ E + K++ +++ I
Sbjct: 497 ALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEI 531
>gi|4505725 peroxin1 [Homo sapiens]
Length = 1283
Score = 177 bits (450), Expect = 1e-44
Identities = 94/232 (40%), Positives = 142/232 (61%), Gaps = 3/232 (1%)
Query: 140 VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199
+ K D ++ IGGL + + + + I+LP K+PELF L I Q G+LLYGPPGTGKTLL
Sbjct: 831 LHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLL 890
Query: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259
A +A + FI V G EL+ K+IG + VR++F+ A+ P I+F DE +SI R
Sbjct: 891 AGVIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRR- 949
Query: 260 EGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPP 319
G R + +LL QLDG E + + V+ AT+R D++D ALLRPGR+D+ + PP
Sbjct: 950 --GHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPP 1007
Query: 320 PNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL 371
P++ +RL+IL + S + L ++L+ +A + +GA++K + A + AL
Sbjct: 1008 PDQVSRLEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEAL 1059
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 177 bits (449), Expect = 2e-44
Identities = 101/265 (38%), Positives = 154/265 (58%), Gaps = 11/265 (4%)
Query: 148 YEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 207
++ +GGL I +KE++ P+ +PE+FE I P+G L YGPPGTGKTL+ARA+A+
Sbjct: 425 FDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANEC 484
Query: 208 D-----CTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 262
F G++ + K++GE R +R LF A + PSIIF DEID + R
Sbjct: 485 SQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSSRQ 544
Query: 263 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 322
S + T+L L +DG ++ I VI ATNR+D +D AL RPGR DR+ F P++
Sbjct: 545 DQIHSSIVSTLLAL---MDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDK 601
Query: 323 EARLDILKIHSRKMN-LTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRER--RVHVT 379
EAR +ILKIH+R N L ++AE G GA++K +C EA + ALR R +++ T
Sbjct: 602 EARKEILKIHTRDWNPKPLDTFLEELAENCVGYCGADIKSICAEAALCALRRRYPQIYTT 661
Query: 380 QEDFEMAVAKVMQKDSEKNMSIKKL 404
E ++ ++ + + ++++K+
Sbjct: 662 SEKLQLDLSSINISAKDFEVAMQKM 686
>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
Length = 1458
Score = 169 bits (427), Expect = 5e-42
Identities = 99/252 (39%), Positives = 145/252 (57%), Gaps = 11/252 (4%)
Query: 148 YEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHT 207
++ IGGL I +KE++ P+ +PE+FE I P+G L YGPPGTGKTL+ARA+A+
Sbjct: 399 FDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANEC 458
Query: 208 D-----CTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 262
F G++ + K++GE R +R LF A PSIIF DEID + R
Sbjct: 459 SQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQ 518
Query: 263 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNE 322
S + T+L L +DG + I VI ATNR+D +D AL RPGR DR+ F P++
Sbjct: 519 DQIHSSIVSTLLAL---MDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQ 575
Query: 323 EARLDILKIHSRKMN-LTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRER--RVHVT 379
+AR IL+IH+R N L ++AE G GA++K +CTEA + ALR R +++ +
Sbjct: 576 KARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYPQIYAS 635
Query: 380 QEDFEMAVAKVM 391
++ V+ ++
Sbjct: 636 SHKLQLDVSSIV 647
>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
Length = 491
Score = 168 bits (426), Expect = 7e-42
Identities = 113/292 (38%), Positives = 163/292 (55%), Gaps = 31/292 (10%)
Query: 139 MVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKT 197
++ + P+ ++ I L + K +KE + LP+ PE F+ GI +P KGVL+ GPPGTGKT
Sbjct: 199 IISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKT 256
Query: 198 LLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSS 257
LLA+AVA TF VS S L K+ GE ++VR LF MAR ++P+ IF+DEIDSI S
Sbjct: 257 LLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSR 316
Query: 258 RLEGGSGGDSEVQRTMLELLNQLDGFEAT-------KNIKVIMATNRIDILDSALLRPGR 310
R G S +R ELL Q+DG T K + V+ ATN +D AL R R
Sbjct: 317 R--GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--R 372
Query: 311 IDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYA 370
++++I P P+ + R ++L+I R++ L ++L IAE M G SGA++ VC +A + A
Sbjct: 373 LEKRIYIPLPSAKGREELLRISLRELELADDVDLASIAENMEGYSGADITNVCRDASLMA 432
Query: 371 LRER-----------------RVHVTQEDFEMAVAKVMQKDSEKNMSIKKLW 405
+R R + T EDFEMA+ KV + S ++ + W
Sbjct: 433 MRRRIEGLTPEEIRNLSKEEMHMPTTMEDFEMALKKVSKSVSAADIERYEKW 484
>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
Length = 490
Score = 167 bits (422), Expect = 2e-41
Identities = 110/292 (37%), Positives = 165/292 (56%), Gaps = 31/292 (10%)
Query: 139 MVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKT 197
+V + P ++ I L++ K ++E + LP+ P+ F+ GI +P KGVL+ GPPGTGKT
Sbjct: 198 IVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFK--GIRRPWKGVLMVGPPGTGKT 255
Query: 198 LLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSS 257
+LA+AVA TF VS S L K+ GE ++VR LF MAR +AP+ IF+DEIDSI S
Sbjct: 256 MLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSR 315
Query: 258 RLEGGSGGDSEVQRTMLELLNQLDGF-------EATKNIKVIMATNRIDILDSALLRPGR 310
R G S +R ELL Q+DG + +K + V+ ATN +D AL R R
Sbjct: 316 R--GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--R 371
Query: 311 IDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYA 370
++++I P P + R ++LKI+ R++ L I L IAE + G SGA++ VC +A + A
Sbjct: 372 LEKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMA 431
Query: 371 LRER-----------------RVHVTQEDFEMAVAKVMQKDSEKNMSIKKLW 405
+R R ++ VT+ DFE+A+ K+ + S ++ + W
Sbjct: 432 MRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAADLEKYEKW 483
>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
Length = 490
Score = 167 bits (422), Expect = 2e-41
Identities = 110/292 (37%), Positives = 165/292 (56%), Gaps = 31/292 (10%)
Query: 139 MVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKT 197
+V + P ++ I L++ K ++E + LP+ P+ F+ GI +P KGVL+ GPPGTGKT
Sbjct: 198 IVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFK--GIRRPWKGVLMVGPPGTGKT 255
Query: 198 LLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSS 257
+LA+AVA TF VS S L K+ GE ++VR LF MAR +AP+ IF+DEIDSI S
Sbjct: 256 MLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSR 315
Query: 258 RLEGGSGGDSEVQRTMLELLNQLDGF-------EATKNIKVIMATNRIDILDSALLRPGR 310
R G S +R ELL Q+DG + +K + V+ ATN +D AL R R
Sbjct: 316 R--GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--R 371
Query: 311 IDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYA 370
++++I P P + R ++LKI+ R++ L I L IAE + G SGA++ VC +A + A
Sbjct: 372 LEKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMA 431
Query: 371 LRER-----------------RVHVTQEDFEMAVAKVMQKDSEKNMSIKKLW 405
+R R ++ VT+ DFE+A+ K+ + S ++ + W
Sbjct: 432 MRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAADLEKYEKW 483
>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
Length = 750
Score = 167 bits (422), Expect = 2e-41
Identities = 105/274 (38%), Positives = 158/274 (57%), Gaps = 23/274 (8%)
Query: 143 VPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARA 202
VP+ T+ IG L+ +E+ I PV++P+ F+ALG+ P GVLL GPPG GKTLLA+A
Sbjct: 469 VPNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKA 528
Query: 203 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 262
VA+ + FI V G EL+ ++GE R VR++F A+ AP +IF DE+D++ R +
Sbjct: 529 VANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRE 588
Query: 263 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRK--IEFPPP 320
+G R + +LL ++DG EA + + ++ ATNR DI+D A+LRPGR+D+ + PPP
Sbjct: 589 TGAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPP 645
Query: 321 NEEARLDILKI---HSRKMNLTRGINLRKIAELM--PGASGAEVKGVCTEAGMYALRER- 374
+ RL ILK + K L +NL IA + +GA++ + EA + ALR+
Sbjct: 646 AD--RLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEM 703
Query: 375 ----------RVHVTQEDFEMAVAKVMQKDSEKN 398
+ V+ + FE A KV S+K+
Sbjct: 704 ARQKSGNEKGELKVSHKHFEEAFKKVRSSISKKD 737
Score = 164 bits (414), Expect = 2e-40
Identities = 90/230 (39%), Positives = 137/230 (59%), Gaps = 1/230 (0%)
Query: 142 KVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLAR 201
++ + +E +GG D +KE+ +++ + ++HPE++ LG+ P+GVLL+GPPG GKTLLA
Sbjct: 152 QISNVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAH 210
Query: 202 AVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEG 261
A+A D ++V+ E+V GE + +RELF A +AP IIF+DEID+I R
Sbjct: 211 AIAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA 270
Query: 262 GSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPN 321
+ + +L ++ L+ AT + VI ATNR D LD AL R GR DR+I P+
Sbjct: 271 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 330
Query: 322 EEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL 371
E +R IL+ RK+ L + + +A L PG GA++ +C EA M A+
Sbjct: 331 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAV 380
>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
Length = 856
Score = 167 bits (422), Expect = 2e-41
Identities = 105/274 (38%), Positives = 158/274 (57%), Gaps = 23/274 (8%)
Query: 143 VPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARA 202
VP+ T+ IG L+ +E+ I PV++P+ F+ALG+ P GVLL GPPG GKTLLA+A
Sbjct: 575 VPNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKA 634
Query: 203 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 262
VA+ + FI V G EL+ ++GE R VR++F A+ AP +IF DE+D++ R +
Sbjct: 635 VANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRE 694
Query: 263 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRK--IEFPPP 320
+G R + +LL ++DG EA + + ++ ATNR DI+D A+LRPGR+D+ + PPP
Sbjct: 695 TGAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPP 751
Query: 321 NEEARLDILKI---HSRKMNLTRGINLRKIAELM--PGASGAEVKGVCTEAGMYALRER- 374
+ RL ILK + K L +NL IA + +GA++ + EA + ALR+
Sbjct: 752 AD--RLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEM 809
Query: 375 ----------RVHVTQEDFEMAVAKVMQKDSEKN 398
+ V+ + FE A KV S+K+
Sbjct: 810 ARQKSGNEKGELKVSHKHFEEAFKKVRSSISKKD 843
Score = 164 bits (414), Expect = 2e-40
Identities = 90/230 (39%), Positives = 137/230 (59%), Gaps = 1/230 (0%)
Query: 142 KVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLAR 201
++ + +E +GG D +KE+ +++ + ++HPE++ LG+ P+GVLL+GPPG GKTLLA
Sbjct: 258 QISNVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAH 316
Query: 202 AVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEG 261
A+A D ++V+ E+V GE + +RELF A +AP IIF+DEID+I R
Sbjct: 317 AIAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA 376
Query: 262 GSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPN 321
+ + +L ++ L+ AT + VI ATNR D LD AL R GR DR+I P+
Sbjct: 377 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 436
Query: 322 EEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYAL 371
E +R IL+ RK+ L + + +A L PG GA++ +C EA M A+
Sbjct: 437 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAV 486
>gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive
factor [Homo sapiens]
Length = 563
Score = 150 bits (380), Expect = 2e-36
Identities = 99/266 (37%), Positives = 149/266 (56%), Gaps = 19/266 (7%)
Query: 144 PDSTYEM--IGGLDKQIKEI-KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLA 200
PD +E IGGLDK+ +I + V PE+ E +G KG+LLYGPPG GKTLLA
Sbjct: 284 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLA 343
Query: 201 RAVAHHTDCTFIRV-SGSELVQKFIGEGARMVRELFVMAREHAPS--------IIFMDEI 251
R + + +V +G E++ K++GE +R+LF A E II DEI
Sbjct: 344 RQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEI 403
Query: 252 DSIGSSRLEGGSGGDSEVQRTML-ELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGR 310
D+I R G G + V T++ +LL+++DG E NI VI TNR D++D ALLRPGR
Sbjct: 404 DAICKQR--GSMAGSTGVHDTVVNQLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGR 461
Query: 311 IDRKIEFPPPNEEARLDILKIHSRKMN----LTRGINLRKIAELMPGASGAEVKGVCTEA 366
++ K+E P+E+ RL IL IH+ +M L+ ++++++A SGAE++G+ A
Sbjct: 462 LEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAA 521
Query: 367 GMYALRERRVHVTQEDFEMAVAKVMQ 392
A+ T+ + +M A+ +Q
Sbjct: 522 QSTAMNRHIKASTKVEVDMEKAESLQ 547
>gi|156564401 vesicle-fusing ATPase [Homo sapiens]
Length = 744
Score = 150 bits (379), Expect = 2e-36
Identities = 99/266 (37%), Positives = 149/266 (56%), Gaps = 19/266 (7%)
Query: 144 PDSTYEM--IGGLDKQIKEI-KEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLA 200
PD +E IGGLDK+ +I + V PE+ E +G KG+LLYGPPG GKTLLA
Sbjct: 211 PDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLA 270
Query: 201 RAVAHHTDCTFIRV-SGSELVQKFIGEGARMVRELFVMAREHAPS--------IIFMDEI 251
R + + +V +G E++ K++GE +R+LF A E II DEI
Sbjct: 271 RQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEI 330
Query: 252 DSIGSSRLEGGSGGDSEVQRTML-ELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGR 310
D+I R G G + V T++ +LL+++DG E NI VI TNR D++D ALLRPGR
Sbjct: 331 DAICKQR--GSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGR 388
Query: 311 IDRKIEFPPPNEEARLDILKIHSRKMN----LTRGINLRKIAELMPGASGAEVKGVCTEA 366
++ K+E P+E+ RL IL IH+ +M L+ ++++++A SGAE++G+ A
Sbjct: 389 LEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAA 448
Query: 367 GMYALRERRVHVTQEDFEMAVAKVMQ 392
A+ T+ + +M A+ +Q
Sbjct: 449 QSTAMNRHIKASTKVEVDMEKAESLQ 474
Score = 35.8 bits (81), Expect = 0.071
Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 10/120 (8%)
Query: 186 VLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIG----EGARMVRELFVMAREH 241
VLL GPP +GKT LA +A ++ FI++ + K IG + ++++F A +
Sbjct: 539 VLLEGPPHSGKTALAAKIAEESNFPFIKICSPD---KMIGFSETAKCQAMKKIFDDAYKS 595
Query: 242 APSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDIL 301
S + +D+I+ + + G + V + +L LL + + + +I T+R D+L
Sbjct: 596 QLSCVVVDDIERL-LDYVPIGPRFSNLVLQALLVLLKKAP--PQGRKLLIIGTTSRKDVL 652
>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
Length = 466
Score = 145 bits (367), Expect = 5e-35
Identities = 90/238 (37%), Positives = 139/238 (58%), Gaps = 12/238 (5%)
Query: 144 PDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKTLLARA 202
P+ + I GLD + +KE + P+++P+LF GI P KG+LLYGPPGTGKTLLA+A
Sbjct: 177 PNIKWNDIIGLDAAKQLVKEAVVYPIRYPQLFT--GILSPWKGLLLYGPPGTGKTLLAKA 234
Query: 203 VAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGG 262
VA TF +S S +V K+ G+ ++VR LF +AR HAPS IF+DE++S+ S R
Sbjct: 235 VATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGTAS 294
Query: 263 SGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRID-ILDSALLRPGRIDRKIEFPPPN 321
G R ELL Q+DG ++++ ++A + + LD A+LR R++++I P+
Sbjct: 295 GGEHEGSLRMKTELLVQMDGLARSEDLVFVLAASNLPWELDCAMLR--RLEKRILVDLPS 352
Query: 322 EEARLDIL------KIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRE 373
EAR ++ SR + L + +++ G SG+++K VC EA M +R+
Sbjct: 353 REARQAMIYHWLPPVSKSRALELHTELEYSVLSQETEGYSGSDIKLVCREAAMRPVRK 410
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,595,617
Number of Sequences: 37866
Number of extensions: 616243
Number of successful extensions: 2948
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 2606
Number of HSP's gapped (non-prelim): 349
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.