Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 24308223
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
(936 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308223 hypothetical protein LOC57577 [Homo sapiens] 1864 0.0
gi|148746195 trichohyalin [Homo sapiens] 96 2e-19
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 72 2e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 1e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 1e-10
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 66 2e-10
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 66 2e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 65 4e-10
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 65 4e-10
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 65 4e-10
gi|221219020 NYD-SP11 protein [Homo sapiens] 64 5e-10
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 64 7e-10
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 64 7e-10
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 64 9e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 2e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 62 2e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 6e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 61 6e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 61 6e-09
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 61 6e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 60 7e-09
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 60 9e-09
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 60 9e-09
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 60 9e-09
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 60 9e-09
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 60 9e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 60 9e-09
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 60 1e-08
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 60 1e-08
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 59 2e-08
>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
Length = 936
Score = 1864 bits (4829), Expect = 0.0
Identities = 936/936 (100%), Positives = 936/936 (100%)
Query: 1 MLLAPQGRSFSKKRMGLNRWKRFTRKPSPKPTFGPDSVEHWIKRVEKASEFAVSNAFFTR 60
MLLAPQGRSFSKKRMGLNRWKRFTRKPSPKPTFGPDSVEHWIKRVEKASEFAVSNAFFTR
Sbjct: 1 MLLAPQGRSFSKKRMGLNRWKRFTRKPSPKPTFGPDSVEHWIKRVEKASEFAVSNAFFTR 60
Query: 61 NSDLPRSPWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVS 120
NSDLPRSPWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVS
Sbjct: 61 NSDLPRSPWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVS 120
Query: 121 SVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQ 180
SVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQ
Sbjct: 121 SVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQ 180
Query: 181 DKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKAL 240
DKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKAL
Sbjct: 181 DKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKAL 240
Query: 241 EAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDE 300
EAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDE
Sbjct: 241 EAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDE 300
Query: 301 EKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVL 360
EKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVL
Sbjct: 301 EKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVL 360
Query: 361 RAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKR 420
RAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKR
Sbjct: 361 RAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKR 420
Query: 421 ELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWE 480
ELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWE
Sbjct: 421 ELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWE 480
Query: 481 KPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTT 540
KPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTT
Sbjct: 481 KPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTT 540
Query: 541 SQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVT 600
SQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVT
Sbjct: 541 SQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVT 600
Query: 601 EAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKA 660
EAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKA
Sbjct: 601 EAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKA 660
Query: 661 MEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKK 720
MEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKK
Sbjct: 661 MEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKK 720
Query: 721 MKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQ 780
MKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQ
Sbjct: 721 MKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQ 780
Query: 781 RKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKK 840
RKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKK
Sbjct: 781 RKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKK 840
Query: 841 IFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLR 900
IFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLR
Sbjct: 841 IFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLR 900
Query: 901 RKVVEILPDFQVPGRYHELYQQSDTWSLSKTSLVNE 936
RKVVEILPDFQVPGRYHELYQQSDTWSLSKTSLVNE
Sbjct: 901 RKVVEILPDFQVPGRYHELYQQSDTWSLSKTSLVNE 936
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 95.5 bits (236), Expect = 2e-19
Identities = 189/901 (20%), Positives = 375/901 (41%), Gaps = 160/901 (17%)
Query: 75 LKTSEQIEDHDEIYAEAQELVND--------WLDTKLKQELASEEEGDAKNTVSSVTIMP 126
LK E+ E H++ Q+L D WL KL++E E++ + +
Sbjct: 458 LKREEETERHEQ-ERRKQQLKRDQEEERRERWL--KLEEEERREQQERREQQLRREQEER 514
Query: 127 EANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQK 186
+ ++ + L L E++ Q+ L K + + ++ R+E + K++Q+
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE--RREQRLKREQE 572
Query: 187 DPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEE 246
+ R + R ++ ++ RL+RE+E +R+E+ LK+ E + L QEE++ + L K+EE
Sbjct: 573 ERRDQLLKREEERRQQRLKREQE---ERLEQRLKRE---EVERLEQEERREQRL--KREE 624
Query: 247 EEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKE 306
E +R L+ E E RR + + +++R++ + E+ + E+++ +E
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL---------EQRLKRE 675
Query: 307 RKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKV---LRAW 363
+ + +E Q E +Q Q R RIK + W+ QL+ R
Sbjct: 676 HEEERRE---QELAEEEQEQAR-----------ERIK----SRIPKWQWQLESEADARQS 717
Query: 364 RDYTRFQKLERETQALENDLREENRKQQL-------ATEYNRKQVLRHCFT-EWQHWHGA 415
+ Y+R +K E + + E + + R+ +L A +++ R FT +WQ +
Sbjct: 718 KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS 777
Query: 416 ELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAV 475
E ++ L+ + R++ + L+A + LPEE + +E +
Sbjct: 778 ERGRQRLS-ARPPLREQRERQLRAEERQQREQR-----FLPEEEEKEQRRRQRREREKEL 831
Query: 476 PPLWEKPPL----------GSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGA 525
L E+ L + R + + L ++ TL A
Sbjct: 832 QFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA 891
Query: 526 EPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQ 585
+P+ Q E LR +QQL+++++++LQ +++ K+ Q
Sbjct: 892 KPALQ----EQLRK-------------------EQQLLQEEEEELQREERE----KRRRQ 924
Query: 586 LAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLR 645
E Q+ E L E Q LL + RE+ R + R L+
Sbjct: 925 EQERQYREEEQLQQEEEQ--LLREEREKRRR---------------QERERQYRKDKKLQ 967
Query: 646 RKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEK 705
+K +QL+ P EK+++QE EK K +EEE E +++
Sbjct: 968 QKEEQLLGEEP--------------------EKRRRQEREK----KYREEE----ELQQE 999
Query: 706 EAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSK 765
E QL R+ EKR ++ E + +K+ + Q+ E + +E E+ L+++ + + +Q +
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
Query: 766 QNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDL 825
+ + EE + +R+ L R +E L ++ Q + + ++ + + +L
Sbjct: 1060 EEQLLGEERET---RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEEL 1116
Query: 826 QEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKF 885
Q+E + +K+ + RE + Q + ++ E ++R R +++ +
Sbjct: 1117 QQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEEL 1176
Query: 886 MKEE----RVKEERRQQLRRKVV---EILPDFQVPGRYHELYQQSD---TWSLSKTSLVN 935
+EE R ++E+R+Q R + E L + RY + Q+SD W K + V
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
Query: 936 E 936
+
Sbjct: 1237 D 1237
Score = 89.0 bits (219), Expect = 2e-17
Identities = 160/748 (21%), Positives = 308/748 (41%), Gaps = 90/748 (12%)
Query: 172 EDLGRKENQDKKQQKDPRLTMEMRHKQVKENR---LRREKELEYQRIEKTLKKSAFLEAQ 228
+ L R++ +++ +QK + E R K+ +E R L+RE+E E R E+ +K Q
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE--RHEQERRKQQLKRDQ 480
Query: 229 CLVQEEKKRKALEAKKEE--EEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNS- 285
+EE++ + L+ ++EE E+ +R +LRRE ERR +++++ +EE Q
Sbjct: 481 ---EEERRERWLKLEEEERREQQERREQQLRREQEERREQ-----RLKRQEEEERLQQRL 532
Query: 286 -SEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKL 344
SE+ + + ++ +E KR +E Q K Q+ ++ + R+K
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Query: 345 GKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQL----ATEYNRKQ 400
+ + +++ ++ R + R ++ ER Q L+ + EE R+QQL E R+Q
Sbjct: 593 EQ-----EERLEQRLKR--EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Query: 401 VLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEAT 460
LR E +RE L +EE ++++ L+ + L EE
Sbjct: 646 QLRREQQE----------RREQRLKREEEEERLEQRLKREHEEERREQ-----ELAEEEQ 690
Query: 461 AMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQH 520
+K+ P W+ + S R Q Q ++
Sbjct: 691 EQARERIKSR-----IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQ--------EQEE 737
Query: 521 KTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQ--EQQKTIL 578
K E Q E Q+ E +Q Q EK ++ Q + +
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQ------RRDFTWQWQAEEKSERGRQRLSARPPLR 791
Query: 579 ELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSR 638
E ++ AE + E E + + R E + Q L E + R
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE--------EEQLQRR 843
Query: 639 NSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQ 698
L+ + L ++ E+R Q+ R L E++K++ A+ QE+ R+
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQK--WRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 699 KRE-AEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPW 757
+++ +E+E +L+R+ EKR ++ +E + ++ + Q+ E + +E E+ +++ +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961
Query: 758 KRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQS 817
K ++Q K+ + EE +R+ R +E L + + +Q + KR Q
Sbjct: 962 KDKKLQQKEEQLLGEEPEK---RRRQEREKKYREEEELQQ---EEEQLLREEREKRRRQE 1015
Query: 818 W-LQY--VIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWI 874
W QY +LQ+E + +K+ + RE + Q + ++ E + R
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR---- 1071
Query: 875 TLRTWKKFVKFMKEERVKEERRQQLRRK 902
R + ++ KEE +++E Q LR +
Sbjct: 1072 --RRQELERQYRKEEELQQEEEQLLREE 1097
Score = 88.2 bits (217), Expect = 3e-17
Identities = 158/797 (19%), Positives = 310/797 (38%), Gaps = 149/797 (18%)
Query: 143 YLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKEN 202
+LEEEE+ L + E+ G +E+Q++++ ++ R + R + +E
Sbjct: 833 FLEEEEQ----------LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
Query: 203 RLRREKELEYQRIEKTLKKSAFL----EAQCLVQEEKKRKALEAKK---EEEEIQREMVK 255
+ RR +++ L+K L E + +E +KR+ E ++ EEE++Q+E +
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 256 LRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVL 315
L RE E+RR RQE Q +K + Q L EE + R+ + K+
Sbjct: 943 LLREEREKRR-----------RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK-- 989
Query: 316 IQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERE 375
++E ++ Q+ +L+ + R K + +W+ R Y + +L++E
Sbjct: 990 ---YREEEELQQEE----EQLLREEREKRRR----QEWE---------RQYRKKDELQQE 1029
Query: 376 TQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDA 435
+ L + RE+ R Q+ +Y ++ L+ + +L + ETR++ +
Sbjct: 1030 EEQLLREEREKRRLQERERQYREEEELQQ-------------EEEQLLGEERETRRRQEL 1076
Query: 436 LLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPL 495
Q +L EE + P K ++ E+ L L
Sbjct: 1077 ERQYRKEEELQQ---------EEEQLLREEPEKRRRQERERQCREEEELQQEEEQL---- 1123
Query: 496 GRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNR 555
L+ + + E Q + LR +K R
Sbjct: 1124 -----------LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK---------RRR 1163
Query: 556 HVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREE-- 613
++Q E+++ + +E+Q E +K Q E Q+ E L + + + +
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223
Query: 614 ----EPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRA 669
EP + ++ V G E + S LR + Q H
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH-------------- 1269
Query: 670 ECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKR 729
+L E++++ E++ + + ++ + E E+E Q E KR +++ ++ K+L +++R
Sbjct: 1270 ----LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
Query: 730 IKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSK----------QNIQVAEEHYSL-- 777
++ ++ E K E LL+++ +P +R K Q + EE L
Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 778 ------FLQRKYMLTWFQRSQ---ESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEE 828
FL+ + L +R Q + RK + +Q S+ R + Q V QE
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV-RRQER 1444
Query: 829 VRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKE 888
RKF Q + R E + + + ++ + DR+ L ++ + ++
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL-------EEEQQLRRQ 1497
Query: 889 ERVKEERRQQLRRKVVE 905
ER ++ R Q+LR + E
Sbjct: 1498 ERDRKFREQELRSQEPE 1514
Score = 87.8 bits (216), Expect = 4e-17
Identities = 172/857 (20%), Positives = 344/857 (40%), Gaps = 105/857 (12%)
Query: 76 KTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYD 135
K ++ E D ++ E +E +W K + L EEE + + E L+
Sbjct: 226 KQQQRRERQDRVFQEEEE--KEW--RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Query: 136 KFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQ------DKKQQKDPR 189
+ +L +EEE+ + L K + ++ R++ + ++++Q+ R
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 190 LTMEMRHKQV--------KENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALE 241
E R +Q+ +E +LRRE+E E R E+ L++ L + ++ E++ + +
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEE--RREQQLRREQQLRREQQLRREQQLRREQ 399
Query: 242 AKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEE 301
+ E++++RE +LRRE RR + E++ ++++ Q E+ + + D
Sbjct: 400 QLRREQQLRREQ-QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 302 KMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLR 361
K +E +R +E Q K +Q+ ++R W KL
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERR--ERWLKL------------------------- 491
Query: 362 AWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRE 421
+ R ++ ER Q L + +EE R+Q+L + +++ + +E Q E +R
Sbjct: 492 --EEEERREQQERREQQLRRE-QEERREQRLKRQEEEERLQQRLRSEQQLRREQE--ERR 546
Query: 422 LALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEK 481
L K E K+++ + L + + EE +K QE
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ--QRLKREQEE-------- 596
Query: 482 PPLGSSGCMLSPPLGRTTTGNLQGS---LQNVSLSAPGNKQHKTLGAEPSQQPGSNETLR 538
L L R L+ Q + P ++ + L Q+ + LR
Sbjct: 597 --------RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648
Query: 539 TTSQKAEPLCLGHFHNRHVFQQQL-----IEKQKKKLQEQQKTILELKKNLQLAEAQWAA 593
Q+ L +Q+L E+++++L E+++ + ++ + QW
Sbjct: 649 REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
Query: 594 EHALAVTEAQSHLLSKPREEE--PRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQL 651
E QS + S+PR++E R + + + + R + ++
Sbjct: 709 ES--EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
Query: 652 MTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLER 711
T + ER QR R L E++++Q A+ + Q E+R E EEKE + +
Sbjct: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLR---AEERQQREQRFLPEEEEKEQRRRQ 823
Query: 712 KRE-EKRLKKMKELEKQKRIKRNQQL----EAIAKEHYERVLLRKKGLEPWK-RLRMQSK 765
+RE EK L+ ++E E+ +R +R QQL + + ++ R ++ + W+ +L + K
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK 883
Query: 766 QNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDL 825
+ +L Q + Q +E L R+ + + Q R + L
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE-------QL 936
Query: 826 QEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKF 885
Q+E + +K+ + R+ K Q + ++ E ++R R ++ K+
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR------RRQEREKKY 990
Query: 886 MKEERVKEERRQQLRRK 902
+EE +++E Q LR +
Sbjct: 991 REEEELQQEEEQLLREE 1007
Score = 87.8 bits (216), Expect = 4e-17
Identities = 192/903 (21%), Positives = 377/903 (41%), Gaps = 144/903 (15%)
Query: 80 QIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIM---PEANGHLKYDK 136
Q + +++ E ++L+ + + + +QE + D K ++ PE + +K
Sbjct: 929 QYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
Query: 137 FDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRH 196
Y EEEE +Q+ + LL + E + +D+ QQ++ +L E R
Sbjct: 989 -----KYREEEE----LQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 197 K--------QVK---------------ENRLRREKELEYQ-RIEKTLKKSAFLEAQCLVQ 232
K Q + E RR +ELE Q R E+ L++ E Q L +
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE---EEQLLRE 1096
Query: 233 EEKKRKALEAK---KEEEEIQREMVKLRREIIERRR--TVKAAWKIEKKRQEENSQ---- 283
E +KR+ E + +EEEE+Q+E +L RE E+RR ++ ++ E++ Q+E Q
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 284 -------NSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQK-----RYFA 331
E+ + + +EE++++E + K ++ + ++E ++ Q+ RY
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
Query: 332 AWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQ 391
+ L + + K + D K+ K R+ +F++LE ++ LR+ +Q
Sbjct: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCK----GRENEQFRQLE------DSQLRDRQSQQD 1266
Query: 392 L------ATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKL 445
L E +R+Q R +H+ E L+RE +++ K+ D Q +L
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE----EQKEAKRRDRKSQEEK--QL 1320
Query: 446 SANGLSGISLPEEATAMVGPPVKNGQETAVPPL--WEKPPLGSSGCMLSPPLGRTTTGNL 503
+E + QE PL E+ + GR
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 504 QGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLI 563
Q L+ K+ + L + +Q + R ++ + L + ++Q +
Sbjct: 1381 Q-RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439
Query: 564 EKQKKK----------LQEQQKTILELKKNLQLAEAQ--WAAEHALAVTEAQSHLLSKPR 611
+Q+++ QE+ + E ++ LQ E Q E E + L + R
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER 1499
Query: 612 EEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAEC 671
+ + R ++ P + L +R+ K L + + +ER QR +
Sbjct: 1500 DRKFREQELRSQEP-----ERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQD 1552
Query: 672 R-RILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKR----EEKRLKKMKELE- 725
R R E+++ ++E + QL QE +R+ R E+K + E++R +E++L++ + +
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Query: 726 -KQKRIKRNQQLEAIAKEHYERVLLR----KKGLEPWKRLRMQSKQNIQVAEEHYSLFLQ 780
+Q+R ++ ++ E + +E E+ L R +K LE +LR Q ++ Q+ + F +
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ-QLRHDRDRKFRE 1671
Query: 781 RKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKK 840
+ +L Q +E R+ + +F + + + QE RK FLQ++
Sbjct: 1672 EEQLL---QEGEEQQLRRQERDRKFREE-----------EQQLRRQERERK----FLQEE 1713
Query: 841 IFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEER-RQQL 899
+ R+ + + Q + E E LR +++ K ++EE+++ ER QQL
Sbjct: 1714 QQLRRQELERKFREEEQLRQETEQEQ---------LRRQERYRKILEEEQLRPEREEQQL 1764
Query: 900 RRK 902
RR+
Sbjct: 1765 RRQ 1767
Score = 74.7 bits (182), Expect = 4e-13
Identities = 83/360 (23%), Positives = 167/360 (46%), Gaps = 22/360 (6%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
+QQL KQ+++ +EQQ+ E ++ + E + + E + L + +EEE R
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
Q+ E R + + R+ +QL + + + R Q+ + L +
Sbjct: 363 QL------RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 416
Query: 679 KKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKR--LKKMKELEKQKRIKRNQQL 736
++ + E++L + + +E QK E E +E +L+R++EE+R LK+ +E E+ ++ +R QQL
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Query: 737 EAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQR------KYMLTWFQR 790
+ +E L+ LE +R Q ++ Q+ E QR + L R
Sbjct: 477 KRDQEEERRERWLK---LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 791 SQESLARKMAQ-ADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMV 849
S++ L R+ + +Q + KR+ Q + + ++E R+ + +++ +
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 850 REVKIDSQGKHEIA--AEHSDRRILWITLR--TWKKFVKFMKEERVKEERRQQLRRKVVE 905
+E +++ + K E E +RR + ++ + +K E +E R+QQLRR+ E
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Score = 68.9 bits (167), Expect = 2e-11
Identities = 80/367 (21%), Positives = 164/367 (44%), Gaps = 36/367 (9%)
Query: 559 QQQLIEKQKKKLQEQQ-KTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRT 617
+QQL +Q+++ +EQQ + +L++ QL Q E Q + R E+
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAE 677
+ + E + + L+R+ ++ LK EE +R E R +
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEER---RDWLKREEET--ERHEQERRKQQ 475
Query: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEK----QKRIKRN 733
K+ QEEE+ + EEE ++ + E +E QL R++EE+R +++K E+ Q+R++
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 734 QQLEAIAKEHYERVLLR--KKGLEPWKR-LRMQSKQN------IQVAEEHYSLFLQRKYM 784
QQL +E E++L R +K LE +R R++ +Q ++ EE L+R+
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 785 LTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRA 844
QR + ++ Q ++ ++ + + Q ++ +E+ + +++ R
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 845 WFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVV 904
+ RE + + + + + EH + R +E+ + EE ++Q R ++
Sbjct: 656 EQRLKREEE-EERLEQRLKREHEEER----------------REQELAEEEQEQARERIK 698
Query: 905 EILPDFQ 911
+P +Q
Sbjct: 699 SRIPKWQ 705
Score = 59.3 bits (142), Expect = 2e-08
Identities = 67/295 (22%), Positives = 137/295 (46%), Gaps = 43/295 (14%)
Query: 632 EGRSDSRNSLSGLRRKPKQLMTPHPI----LKAMEE--RAIQRAECRRILAEKKKKQEEE 685
E + R + LR++ ++L P L+ EE R ++R E RR E++++Q+
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 686 KLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYE 745
+ Q +++E ++RE +E+ + + +RE++ ++ ++L +++ +R QQL +E
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 746 RVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLAR--KMAQAD 803
LR++ E + +++ +Q ++ ++ L+R+ L R ++ L R ++ +
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQ-----LRREQQL----RREQQLRREQQLRREQ 411
Query: 804 QFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRA---------WFNMVREVKI 854
Q + L+R Q + QEE R H +++ R W E +
Sbjct: 412 QLRREQQLRRE-----QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466
Query: 855 DSQGKHEIAA---EHSDRRILWITLRTWKKFVKFMKEERVKEERR-QQLRRKVVE 905
Q + + + +RR W+ L +E R ++ERR QQLRR+ E
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEE--------EERREQQERREQQLRREQEE 513
Score = 54.7 bits (130), Expect = 4e-07
Identities = 67/284 (23%), Positives = 130/284 (45%), Gaps = 16/284 (5%)
Query: 167 DSAMMEDLGRKENQDKKQQK----DPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKS 222
D + E+ G++ Q +++Q+ + E + + + +R RR++EL QR E ++
Sbjct: 126 DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185
Query: 223 AFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENS 282
E + L Q K + E EE+ +RE+++LRR+ E ++ + ++RQ+
Sbjct: 186 RRAEEEQL-QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR------RERQDRVF 238
Query: 283 QNSSEKVMFQSTHILPDEEKMVKE----RKRKLKEVLIQTFKENQQCQKRYFAAWHKLIL 338
Q EK + +L EE+ ++E R+R+L+E Q K +Q +R +
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 339 DHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNR 398
R + + + + + R + R Q+ ER Q L + +EE R+QQL E
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE-QEERREQQLRREQEE 357
Query: 399 KQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASL 442
++ + E + + L+RE L +E+ ++ L + L
Sbjct: 358 ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Score = 54.7 bits (130), Expect = 4e-07
Identities = 120/586 (20%), Positives = 243/586 (41%), Gaps = 76/586 (12%)
Query: 174 LGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQE 233
L R+E + K +++ +L + R +Q++++R R+ +E E Q + + E Q + ++
Sbjct: 1383 LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ 1442
Query: 234 EKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQS 293
E++RK LE EE+++++E R+ E + ++ E++ Q+ + Q K +
Sbjct: 1443 ERERKFLE---EEQQLRQER---HRKFREEEQLLQ-----EREEQQLHRQERDRKFL--- 1488
Query: 294 THILPDEEKMVK--ERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLS 351
+EE+ ++ ER RK +E +++ Q+ ++++ +L HR + +
Sbjct: 1489 -----EEEQQLRRQERDRKFREQELRS----QEPERKFLEEEQQL---HRQQRQRKFLQE 1536
Query: 352 DWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLAT-EYNRK-----QVLRHC 405
+ +++ + R R +K E Q LR+E +QQL+ E +RK Q +R
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQ-----LRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591
Query: 406 FTEWQHWHGAELLKRELA---LTKEETRK--KMDALLQAASLGKLSANGLSGISLPEEAT 460
E + + L+R+ L +E RK + + LLQ +L L EE
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651
Query: 461 AMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQH 520
+ + E+ L LQ ++
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQL----------------------LQEGEEQQLRRQER 1689
Query: 521 KTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQL---IEKQKKKLQEQQKTI 577
E QQ E R Q+ + L + ++QL E+++ + QE+ + I
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 578 LELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQ-----MLVNSPVASPGTE 632
LE ++ E Q + L + REE+ Q + E
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Query: 633 GRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKA 692
+ + R + +QL + +ER Q + ++K ++EE++L Q +
Sbjct: 1810 QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ-EE 1868
Query: 693 QEEERQKREAEEKEAQLER-KREEKRLKKMKELEKQKRIKRNQQLE 737
+++ RQ+RE + +E + R ++EE+R +++ E++ Q+ + LE
Sbjct: 1869 EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLE 1914
Score = 52.8 bits (125), Expect = 2e-06
Identities = 77/361 (21%), Positives = 152/361 (42%), Gaps = 40/361 (11%)
Query: 564 EKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVN 623
+++++K QEQ++ + E ++ + E + E EE R + +
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ 194
Query: 624 SPVASPGTEGRSDS---RNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECR-RILAEKK 679
S E + R L LRRK + EE+ QR E + R+ E++
Sbjct: 195 SCKGHETEEFPDEEQLRRRELLELRRKGR------------EEKQQQRRERQDRVFQEEE 242
Query: 680 KK----------------QEEEKLAQLKAQEEERQKREAEEKEAQLERKREE---KRLKK 720
+K QEEE Q + QEEE Q R+ E +E + ER+ EE +RL++
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 721 MKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQ 780
++L +++ +R +Q E +E ER +++ E R + ++ Q+ E +
Sbjct: 303 EQQLRRKQEEERREQQEE-RREQQERREQQEERREQQLRREQEERREQQLRREQEE---E 358
Query: 781 RKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKK 840
R+ ++ +E +++ + Q + L+R Q + + ++++R+ +++
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 841 IFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLR 900
+ R + + + KHE + R W K + E +E R+QQL+
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE-ETERHEQERRKQQLK 477
Query: 901 R 901
R
Sbjct: 478 R 478
Score = 52.4 bits (124), Expect = 2e-06
Identities = 71/359 (19%), Positives = 156/359 (43%), Gaps = 66/359 (18%)
Query: 563 IEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEP-----RT 617
+E+QK + QEQ++ +E ++ L+ E Q + L + REE+ R
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAM--EERAIQRAECRRIL 675
+ L P LRR+ ++ H + EE+ +Q E +++
Sbjct: 1643 RKFLEEEPQ-----------------LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
Query: 676 AEKKKKQEEEKLAQLKAQEEERQ--KREAEEKEAQLERK-REEKRLK---KMKELEKQKR 729
+++ ++ E+ QL+ QE ER+ + E + + +LERK REE++L+ + ++L +Q+R
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745
Query: 730 IKRNQQLEAIAKEHYERVLLRK---KGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLT 786
++ + E + E E+ L R+ + ++LR + ++ ++E F + + +
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL-- 1803
Query: 787 WFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWF 846
++ +E + Q D Y W + + L+E+ ++
Sbjct: 1804 --RQEREEQQLRPQQRDGKY----------RWEEEQLQLEEQEQR--------------- 1836
Query: 847 NMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVE 905
+ +E + + + A + RR W++ + ++ER ++ R + +RR+ E
Sbjct: 1837 -LRQERDRQYRAEEQFATQEKSRR---EEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
Score = 52.0 bits (123), Expect = 3e-06
Identities = 90/456 (19%), Positives = 197/456 (43%), Gaps = 53/456 (11%)
Query: 8 RSFSKKRMGLNRWKRFTRKPSPKPTFGPDSVEHWIKRVEKASEFAVSNAFFTRNSDLPRS 67
R F ++ L R +R RK + + +++ ++ F L R
Sbjct: 1485 RKFLEEEQQLRRQER-DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 68 PWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPE 127
GQ ++ +D D + E ++L + + +L S +E D K + + +
Sbjct: 1544 ERGQ-------QRRQDRDRKFREEEQLRQEREEQQL-----SRQERDRKFRLEEQKVRRQ 1591
Query: 128 ANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKD 187
KF + L +E +++ D + D ++++ R+E Q +Q++D
Sbjct: 1592 EQER----KFMEDEQQLRRQEGQQQLRQERDRKFRE---DEQLLQE--REEQQLHRQERD 1642
Query: 188 PRLTME--MRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKE 245
+ E +Q +E +LR +++ +++ E+ L++ E Q L ++E+ RK E E
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG---EEQQLRRQERDRKFRE---E 1696
Query: 246 EEEIQR---------EMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHI 296
E++++R E +LRR+ +ER+ + + E ++++ Q K++ + +
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL-EEEQL 1755
Query: 297 LPDEEKMV---KERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDW 353
P+ E+ +ER RK +E Q +E ++ Q R + K + +++ +
Sbjct: 1756 RPEREEQQLRRQERDRKFREE-EQLRQEREEQQLRSQESDRKFREEEQLRQERE------ 1808
Query: 354 KIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEY--NRKQVLRHCFTEWQH 411
+ QL+ + Y R+++ + + + E LR+E +Q A E +++ R WQ
Sbjct: 1809 EQQLRPQQRDGKY-RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867
Query: 412 WHGAELLKRELALTKEETRKKMDALLQAASLGKLSA 447
+RE L +E R++ + +G++ +
Sbjct: 1868 EEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKS 1903
Score = 49.3 bits (116), Expect = 2e-05
Identities = 57/276 (20%), Positives = 127/276 (46%), Gaps = 11/276 (3%)
Query: 634 RSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQ 693
R D + SL RR+ + P + +EE QR +R E++ + EE+ + +
Sbjct: 102 RCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERL 161
Query: 694 EEERQKREAEE--KEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRK 751
E+ ++R EE ++ Q ++REE+R ++ ++L+ K + + + E + LR+
Sbjct: 162 EQRDRQRRDEELWRQRQEWQEREERRAEE-EQLQSCKGHETEEFPDEEQLRRRELLELRR 220
Query: 752 KGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQI-- 809
KG E ++ R + + + EE + + ++ QE ++ + + Q+
Sbjct: 221 KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK 280
Query: 810 LLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDR 869
L ++ ++ Q Q+ +R+ ++++ R RE + + + + E + +R
Sbjct: 281 LERQELRRERQEEEQQQQRLRR------EQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 870 RILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVE 905
R + ++ + ++ E+ +E R QQLRR+ E
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Score = 45.8 bits (107), Expect = 2e-04
Identities = 81/375 (21%), Positives = 172/375 (45%), Gaps = 55/375 (14%)
Query: 562 LIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQML 621
L E+Q+ + QE+++ L+ ++ L+ E + + + K REEE + +
Sbjct: 1377 LEEEQRLRRQERERKFLKEEQQLRCQERE---------QQLRQDRDRKFREEEQQLSRQE 1427
Query: 622 VNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKK 681
+ + R R + +QL EE+ +Q E +++ +++ +
Sbjct: 1428 RDRKFREEEQQVRRQERERK--FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 682 QEEEKLAQLKAQEEERQKREAE-----------EKEAQLER-KREEKRLKKMKELEKQKR 729
+ E+ QL+ QE +R+ RE E E+E QL R +R+ K L++ ++L +Q+R
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 730 IKRNQQ--------LEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQR 781
++ +Q E + +E E+ L R+ E ++ R++ +Q ++ +E F++
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQ---ERDRKFRLE-EQKVR-RQEQERKFMED 1600
Query: 782 KYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQ---------SWLQYVIDLQEEVRKF 832
+ L Q Q+ L ++ + + Q+L +R Q +L+ L+ + R+
Sbjct: 1601 EQQLR-RQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659
Query: 833 CVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRIL--WITLRTWKKFVKFMKEER 890
+ + + FR +++E + + ++ + DR+ LR ++ KF++EE
Sbjct: 1660 QLRHDRDRKFREEEQLLQEGE-----EQQLRRQERDRKFREEEQQLRRQERERKFLQEE- 1713
Query: 891 VKEERRQQLRRKVVE 905
++ RRQ+L RK E
Sbjct: 1714 -QQLRRQELERKFRE 1727
Score = 41.2 bits (95), Expect = 0.005
Identities = 49/241 (20%), Positives = 113/241 (46%), Gaps = 20/241 (8%)
Query: 675 LAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLE----RKREEKRLKKMKEL-EKQKR 729
L E+K+ + + K + L+ + +E +R E ++ QLE ++R +KR ++ +EL E +++
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 730 IKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYS------LFLQRKY 783
++ ++LE ++ + L R++ + R ++ +Q + H + L+R+
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
Query: 784 MLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFR 843
+L ++ +E K Q + ++ + + W + L++E K +++ R
Sbjct: 215 LLELRRKGRE---EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK----LQEEEPQR 267
Query: 844 AWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEER--VKEERRQQLRR 901
E ++ + E+ E + LR ++ + +EER +EERR+Q R
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 902 K 902
+
Sbjct: 328 R 328
Score = 41.2 bits (95), Expect = 0.005
Identities = 50/219 (22%), Positives = 98/219 (44%), Gaps = 24/219 (10%)
Query: 564 EKQKKKLQEQQKTILELKKNL--QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQML 621
E+Q+ + QE+++ L+ ++ L Q E ++ E L Q L + R + +
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK------I 1749
Query: 622 VNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKK 681
+ P E + R R+ +QL + EE+ ++ E R E+++
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLR------QEREEQQLRSQESDRKFREEEQL 1803
Query: 682 QEEEKLAQLKAQEE------ERQKREAEEKEAQL--ERKREEKRLKKMKELEKQKRIKRN 733
++E + QL+ Q+ E ++ + EE+E +L ER R+ + ++ EK +R ++
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
Query: 734 QQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAE 772
E K ER RK E +R + + +++ QV E
Sbjct: 1864 LWQEEEQKRRQERE--RKLREEHIRRQQKEEQRHRQVGE 1900
Score = 40.8 bits (94), Expect = 0.006
Identities = 54/245 (22%), Positives = 116/245 (47%), Gaps = 35/245 (14%)
Query: 200 KENRLR---REKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKL 256
+E R R +E L+ +R E+ ++ + Q + ++R+ ++E E + E
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 257 RREIIERRRTVKAAWKIEKKRQE--ENSQNSSEKVMFQS-----THILPDEEKMVKERKR 309
++E +E+R + ++ ++RQE E + +E+ QS T PDEE++ R+R
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL---RRR 213
Query: 310 KLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRF 369
+L E L + +E +Q Q+R + + ++ + +W+ + VLR
Sbjct: 214 ELLE-LRRKGREEKQQQRR----------ERQDRVFQEEEEKEWRKRETVLR-----KEE 257
Query: 370 QKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEET 429
+KL+ E + +L+EE ++ + R+++ R E Q + L+RE L +++
Sbjct: 258 EKLQEEEPQRQRELQEE---EEQLRKLERQELRRERQEEEQQ---QQRLRREQQLRRKQE 311
Query: 430 RKKMD 434
++ +
Sbjct: 312 EERRE 316
Score = 37.7 bits (86), Expect = 0.050
Identities = 59/270 (21%), Positives = 120/270 (44%), Gaps = 61/270 (22%)
Query: 180 QDKKQQKDPRLTMEMRHKQVKEN--RLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKR 237
QD++Q++D R E R +Q++E + RR+K E +R E + +++++
Sbjct: 111 QDRRQEEDQR-RFEPRDRQLEEEPGQRRRQKRQEQER--------ELAEGEEQSEKQERL 161
Query: 238 KALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHIL 297
+ + ++ +EE+ R+ R+E ER E++R EE S + T
Sbjct: 162 EQRDRQRRDEELWRQ----RQEWQER----------EERRAEEEQLQSCKG---HETEEF 204
Query: 298 PDEEKMVK------------ERKRKLKEVLIQTFKENQQCQKRYFAAWHK---LILDHRI 342
PDEE++ + E++++ +E + F+E ++ + W K ++
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE------WRKRETVLRKEEE 258
Query: 343 KLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVL 402
KL + ++Q + + +KLER Q L + +EE ++QQ R+Q L
Sbjct: 259 KLQEEEPQRQRELQ-------EEEEQLRKLER--QELRRERQEEEQQQQ---RLRREQQL 306
Query: 403 RHCFTEWQHWHGAELLKRELALTKEETRKK 432
R E + E +++ ++E R++
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERRE 336
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 72.0 bits (175), Expect = 2e-12
Identities = 148/668 (22%), Positives = 268/668 (40%), Gaps = 121/668 (18%)
Query: 76 KTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYD 135
+ E++ D D A +EL D + + + E+ A+ V + + N LK
Sbjct: 334 RCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLTAARARGDKVHELEKENLQLK-S 392
Query: 136 KFDDLCGYLEEEEESTTVQKFIDHLLHKNVV-DSAMMEDLGRKEN---QDKKQQKDPRLT 191
K DL E + T +K I+ LL +N+V + A + + + + ++ K+ L+
Sbjct: 393 KLHDL------ELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKNADLS 446
Query: 192 MEMRHKQVKE-NRLRREKELEYQRIEKTLKKSAF-LEAQCLVQEEKKRKALEAKKEEEEI 249
R V E N + L+ ++ ++L+ + L LV EE K E +KE ++
Sbjct: 447 DASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQL 506
Query: 250 QREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKR 309
+++ KL+ ++ ER +K+ ++ + SE+++ + + D E + ++ R
Sbjct: 507 SKKIEKLQTQL-ER-----------EKQSNQDLETLSEELIREKEQLQSDMETLKADKAR 554
Query: 310 KLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRF 369
++K++ Q+ A W L R ++ + D
Sbjct: 555 QIKDL-------EQEKDHLNRAMWS---LRERSQVSSEARMKD----------------- 587
Query: 370 QKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEET 429
+E+E +AL + E N K E+ ++Q+ R + AE L+REL +EE
Sbjct: 588 --VEKENKALHQTVTEANGKLS-QLEFEKRQLHRDLEQAKEKGERAEKLERELQRLQEEN 644
Query: 430 RKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGC 489
G+L+ S + E+ A+ S G
Sbjct: 645 -------------GRLARKVTSLETATEKVEALEHE--------------------SQGL 671
Query: 490 MLSPPLGRTTTGNLQGSLQNVSLSAPG-NKQHKTLGAEPSQQPGSNETLRTTSQKAEPLC 548
L RT +L +LQNVSL G + +K L AE + ET+R TS K +
Sbjct: 672 QLE---NRTLRKSLD-TLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQM- 726
Query: 549 LGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVT----EAQS 604
E++ ++L+ +++ EL+KN+ L +A L ++ A++
Sbjct: 727 ---------------ERENQQLEREKE---ELRKNVDLLKALGKKSERLELSYQSVSAEN 768
Query: 605 HLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEER 664
L + E Q L S + E R R L LR QL KA+E+
Sbjct: 769 LRLQQSLESSSHKTQTL-ESELGELEAE-RQALRRDLEALRLANAQLEGAEKDRKALEQE 826
Query: 665 AIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQL---ERKREEKRLKKM 721
Q + +++L ++ K+ ++ + ++ K A EKE++ E R K+
Sbjct: 827 VAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKL 886
Query: 722 KELEKQKR 729
KELEK R
Sbjct: 887 KELEKDNR 894
Score = 44.3 bits (103), Expect = 5e-04
Identities = 159/746 (21%), Positives = 288/746 (38%), Gaps = 104/746 (13%)
Query: 127 EANGHLKYDKFD------DLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQ 180
EANG L +F+ DL E+ E + +++ + L +N L RK
Sbjct: 601 EANGKLSQLEFEKRQLHRDLEQAKEKGERAEKLERELQRLQEEN-------GRLARKVTS 653
Query: 181 -DKKQQKDPRLTMEMRHKQVKENRLRREKE------LEYQRIEKTLKK--SAFLEAQCLV 231
+ +K L E + Q++ LR+ + L+ + +E+ K+ + LE + LV
Sbjct: 654 LETATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLV 713
Query: 232 QEEK--KRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKV 289
+ + K + ++E ++++RE +LR+ + + K + ++E Q +++N +
Sbjct: 714 ETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQ 773
Query: 290 MFQS----THILPDEEKMVKERKRKLKEVLIQTFKENQQCQ----KRYFAAWHKLILDHR 341
+S T L E ++ ++ L+ L N Q + R L+
Sbjct: 774 SLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKD 833
Query: 342 IKLGKAGTLSDW-KIQLKVLRAWRDYTRFQKLERETQALENDL---REENRKQQLATEYN 397
KL + W +++LK + +E+E++AL+ +L R+ K + + N
Sbjct: 834 KKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDN 893
Query: 398 R---KQVLRHCFTEWQHWHGAELLKRELALTK---EETRKKMDALLQAASLGKLSANGLS 451
R KQV H T L+ +L L K ++ ++D L Q +L GL+
Sbjct: 894 RDLTKQVTVHART-------LTTLREDLVLEKLKSQQLSSELDKLSQ-----ELEKVGLN 941
Query: 452 GISLPEEATAMVGPPVK-------NGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQ 504
L +E + K + +T + EK L + L R LQ
Sbjct: 942 RELLLQEDDSGSDTKYKILEGRNESALKTTLAMKEEKIVLLEAQMEEKASLNRQLESELQ 1001
Query: 505 ----------------GSLQNVSLSAPGNKQHKTLGAEPSQQPGSNE-TLRTTSQKAEPL 547
LQN S P K + + + PG E T+ K +
Sbjct: 1002 MLKKECETLRQNQGEGQHLQN-SFKHPAGKTAASHQGKEAWGPGHKEATMELLRVKDRAI 1060
Query: 548 CLGHFHNRHVFQQQLIEKQKKKLQEQQKT----ILEL-KKNLQLAEAQWAAEHALAVTEA 602
L + ++QL+++Q + L+ Q T IL L K++ L E + A +
Sbjct: 1061 ELERNNAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQSAFLQEHNTTLQTQTAKLQV 1120
Query: 603 QSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAME 662
++ LS +L N A TE S L+R+ +Q L A
Sbjct: 1121 ENSTLSSQSAALTAQYTLLQNHHTAKE-TENES--------LQRQQEQ-------LTAAY 1164
Query: 663 ERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMK 722
E +Q E L E++ + E + Q + + E E KE +R LK+
Sbjct: 1165 EALLQDHEHLGTLHERQSAEYEALIRQHSCLKTLHRNLELEHKEL---GERHGDMLKRKA 1221
Query: 723 ELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRK 782
ELE+++++ ++ EA+ +E L + L + + Q+ E+ L K
Sbjct: 1222 ELEEREKVLTTER-EALQQEQRTNALAMGENQRLRGELDRVNFLHHQLKGEYEELHAHTK 1280
Query: 783 YMLTWFQRSQESLARKMAQADQFYSQ 808
+ T +Q L R A+ D+ Q
Sbjct: 1281 ELKTSLNNAQLELNRWQARFDELKEQ 1306
Score = 42.7 bits (99), Expect = 0.002
Identities = 167/801 (20%), Positives = 302/801 (37%), Gaps = 133/801 (16%)
Query: 102 KLKQELA--SEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDH 159
KL++EL EE G V+S+ E L+++ + E+ T++K +D
Sbjct: 632 KLERELQRLQEENGRLARKVTSLETATEKVEALEHESQG-------LQLENRTLRKSLDT 684
Query: 160 LLHKNVVDSAMMEDLGRKENQ-DKKQQKDPRLTMEMRHKQVKENRLRREK---ELEYQRI 215
L +NV S +E L R Q D + + RL MR K ++ RE E E + +
Sbjct: 685 L--QNV--SLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKEEL 740
Query: 216 EKTL-------KKSAFLEA-------------QCLVQEEKKRKALEAKKEEEEIQREMVK 255
K + KKS LE Q L K + LE++ E E +R+
Sbjct: 741 RKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAERQA-- 798
Query: 256 LRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKR-----K 310
LRR++ E R A Q E ++ + + + + D++ + KE KR +
Sbjct: 799 LRRDL-EALRLANA--------QLEGAEKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVE 849
Query: 311 LKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLS--------DWKIQLKVLRA 362
LK+ ++ ++ A K + R GK L + + L
Sbjct: 850 LKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDLTKQVTVHARTLTT 909
Query: 363 WRDYTRFQKLERETQALEND-LREENRKQQLATEYNRKQVLRHCFTEWQHWHGAE--LLK 419
R+ +KL+ + + E D L +E K L E ++ T+++ G LK
Sbjct: 910 LREDLVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQEDDSGSDTKYKILEGRNESALK 969
Query: 420 RELALTKEET------------------------RKKMDALLQAASLGKLSANGLSG--- 452
LA+ +E+ +K+ + L Q G+ N
Sbjct: 970 TTLAMKEEKIVLLEAQMEEKASLNRQLESELQMLKKECETLRQNQGEGQHLQNSFKHPAG 1029
Query: 453 -ISLPEEATAMVGPPVKNG-------QETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQ 504
+ + GP K ++ A+ L + +L L T N+
Sbjct: 1030 KTAASHQGKEAWGPGHKEATMELLRVKDRAIELERNNAALQAEKQLLKEQLQHLETQNVT 1089
Query: 505 GSLQNVSL---SAPGNKQHKTLGAEPSQQPGSNETLRTTSQK--AEPLCLGHFHNRHVFQ 559
S Q ++L SA + + TL + ++ N TL + S A+ L + H +
Sbjct: 1090 FSSQILTLQKQSAFLQEHNTTLQTQTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETE 1149
Query: 560 QQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQ 619
+ +++Q+++L + +L+ ++L + +AE+ A+ S L + R E +
Sbjct: 1150 NESLQRQQEQLTAAYEALLQDHEHLGTLHERQSAEYE-ALIRQHSCLKTLHRNLELEHKE 1208
Query: 620 MLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEE-RAIQRAECRRILAEK 678
+ E D + L + K L T L+ + A+ E +R+ E
Sbjct: 1209 L----------GERHGDMLKRKAELEEREKVLTTEREALQQEQRTNALAMGENQRLRGEL 1258
Query: 679 KKKQEEEKLAQLKAQEEERQKREAEEK----EAQLERKREEKRLKKMKELEKQKRIKRNQ 734
+ QLK + EE E K AQLE R + R ++KE + I +
Sbjct: 1259 DRVNFLHH--QLKGEYEELHAHTKELKTSLNNAQLELNRWQARFDELKEQHQTMDISLTK 1316
Query: 735 ---------QLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYML 785
+L+ +E +L + + L ++ ++ QN++ E+++ Q L
Sbjct: 1317 LDNHCELLSRLKGNLEEENHHLLSQIQLLSQQNQMLLE--QNMENKEQYHEEQKQYIDKL 1374
Query: 786 TWFQRSQESLARKMAQADQFY 806
+R +E L K+ +FY
Sbjct: 1375 NALRRHKEKLEEKIMDQYKFY 1395
Score = 37.4 bits (85), Expect = 0.066
Identities = 57/268 (21%), Positives = 116/268 (43%), Gaps = 25/268 (9%)
Query: 677 EKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQL 736
EK+ Q +K+ +L+ Q E ++ + + E RE+++L+ E K + ++ + L
Sbjct: 500 EKENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDL 559
Query: 737 EAIAKEHYERVL--LRKKG-LEPWKRLRMQSKQN---IQVAEEHYSLFLQRKYMLTWFQR 790
E K+H R + LR++ + R++ K+N Q E Q ++ R
Sbjct: 560 EQ-EKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHR 618
Query: 791 SQESLARKMAQADQFYSQI---------LLKRV--IQSWLQYVIDLQEEVRKFCVHFLQK 839
E K +A++ ++ L ++V +++ + V L+ E + L+
Sbjct: 619 DLEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGL---QLEN 675
Query: 840 KIFRAWFNMVREVKIDSQG----KHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEER 895
+ R + ++ V + +G ++ AE+ + R L T+R + M+ E + ER
Sbjct: 676 RTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLER 735
Query: 896 RQQLRRKVVEILPDFQVPGRYHELYQQS 923
++ RK V++L EL QS
Sbjct: 736 EKEELRKNVDLLKALGKKSERLELSYQS 763
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 69.7 bits (169), Expect = 1e-11
Identities = 117/639 (18%), Positives = 266/639 (41%), Gaps = 57/639 (8%)
Query: 148 EESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRRE 207
EE T + + L++N + + ++ + + + + +++ K++K +L R
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKR-KLERA 258
Query: 208 KELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTV 267
K L Q TL++ + + + L ++EKK +K+EE++ R+ +LR + + R
Sbjct: 259 KFLLPQVQTNTLQEEMWRQEEELREQEKK-----IRKQEEKMWRQEERLREQEGKMREQE 313
Query: 268 KAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQK 327
+ W+ EK+ +E+ + ++ + L ++E+ ++E++ K+ E + ++ ++ +
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 328 RYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLE---RETQALENDLR 384
+ W + K + K++ + R W R ++ E RE + + +
Sbjct: 374 QEERLWEQ---------EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVE 424
Query: 385 EENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGK 444
+ ++++ + + + E + E RE T E +KM Q ++ +
Sbjct: 425 KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQK--QEENMWE 482
Query: 445 LSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQ 504
LPE+ + QE + EK + R Q
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 505 GSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIE 564
+++ K E + + E + T + E + +++ +
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMR----------EEERMR 592
Query: 565 KQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNS 624
+++KK++E+++ + E ++ +Q E + + E K +E+E + +
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQE-----EKMWEQEEKMQEQEEKMWEQ---- 643
Query: 625 PVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK--KKKQ 682
E + + +R P+Q K E+ +Q E + EK KK Q
Sbjct: 644 ------EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ 697
Query: 683 EEEKLA--QLKAQEEE----RQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQL 736
E+EK Q K +EEE R+K+ EE+E + R++EEK ++ +++++Q+ Q+
Sbjct: 698 EQEKKTWDQEKMREEESMREREKKMREEEE--MMREQEEKMQEQEEKMQEQEEEMWEQEE 755
Query: 737 EAIAKEH--YERVLLRKKGLEPWKRLRMQSKQNIQVAEE 773
+ +E +E+ L ++ + W+ +MQ ++ I EE
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/306 (23%), Positives = 132/306 (43%), Gaps = 25/306 (8%)
Query: 144 LEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENR 203
L E+EE Q+ + + K + M E + +Q++K Q++ R+ E K +E
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR-EREKKMREEEE 464
Query: 204 LRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKK---EEEEIQREMVKLRREI 260
RE+E + Q+ E+ + + E Q E+K K E +K +EE+I + K+R +
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524
Query: 261 IERRRTVKAAWKIEKKRQEENSQ-NSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTF 319
E K W+ EK R++E+ EK+ Q + EE+M K+ + + K+ Q
Sbjct: 525 -EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 320 K----ENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERE 375
K E + +++ +++ + K+ + + K+Q + + W + Q+ E +
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQE----QEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 376 TQALENDLREENRK---QQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKK 432
E + E+ K QQ E K W+H E K + K ++K
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEKL--------WEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 433 MDALLQ 438
M+ Q
Sbjct: 692 MEKKTQ 697
Score = 59.3 bits (142), Expect = 2e-08
Identities = 63/335 (18%), Positives = 146/335 (43%), Gaps = 21/335 (6%)
Query: 79 EQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFD 138
E+I D +E++ + +++ W K++++ E + K + + K +
Sbjct: 518 EKIRDQEEMWGQEKKM---WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 139 DLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHK- 197
+ + ++EE+ ++ + + M E + + Q++K Q+ E K
Sbjct: 575 EKKTW-DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 198 QVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLR 257
Q +E ++ ++E +++ EK ++ E + + E +K + E +E+EE E K+
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 258 REIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQ 317
++ E+ K W EK R+EE+ + +K+ +EE+M++E++ K++E
Sbjct: 694 KKTQEQE---KKTWDQEKMREEESMREREKKMR--------EEEEMMREQEEKMQEQ--- 739
Query: 318 TFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQ 377
+E Q Q+ + + + K+ + L + K +L ++ + + E + +
Sbjct: 740 --EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797
Query: 378 ALENDLREENRKQQLATEYNRKQVLRHCFTEWQHW 412
E +R + K + E R Q + E + W
Sbjct: 798 DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMW 832
Score = 58.5 bits (140), Expect = 3e-08
Identities = 59/274 (21%), Positives = 129/274 (47%), Gaps = 31/274 (11%)
Query: 558 FQQQLIEKQKKKL------QEQQKTILELKKNLQLAEAQWAAEHAL----AVTEAQSHLL 607
+QQQ + +QK+KL QEQ++ I E ++ ++ E W E + + E + +
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547
Query: 608 S---KPREEEPRTC----QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKA 660
K R++E + +M + T + + +R + K++ +++
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 661 MEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKR-EEKRLK 719
EE+ ++ E + EK +QEE K QE+E + E EEK + E K E++RL
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEE------KMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 720 KMKE-LEKQKRIKRNQQLEAIAKEHYERVLLRKKGLE----PWKRLRMQSKQNIQVAEEH 774
+ KE L + ++++ ++++ ++ +E+ + KK E W + +M+ +++++ E
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR--ERE 719
Query: 775 YSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQ 808
+ + + M ++ QE + Q ++ + Q
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ 753
Score = 53.9 bits (128), Expect = 7e-07
Identities = 103/591 (17%), Positives = 232/591 (39%), Gaps = 66/591 (11%)
Query: 145 EEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRL 204
+EE+ +K + + M R Q+K+ ++ + + + +++
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER 405
Query: 205 RREKELEYQRIEKTLKK-SAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIER 263
REKE + EK ++ E + + ++EKK + E K +EEE RE K RE E
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465
Query: 264 RRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQ 323
R + EK +++E + E+ +Q + +EK+ ++ K + +E I +E
Sbjct: 466 MREQE-----EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Query: 324 QCQKRYFAAWHKLILDHRIKLGKAGTL-SDWKIQLKVLRAWRDYTRFQKLERETQALEND 382
+ Q+ + K+ +++ + + K++ + + W R +K +E + D
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580
Query: 383 LREENRKQQLATEYNRK-----QVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALL 437
E+ R+++ E +K +++R + Q + E +EE ++ + +
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 438 --QAASLGKLSANGLSGISLPEEATAMVGPPVKNGQE---TAVPPLWEKPPLGSSGCMLS 492
Q + + LPE+ + QE +WE+ +
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK-----K 695
Query: 493 PPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHF 552
T + + + S+ ++ K + E E ++ +K +
Sbjct: 696 TQEQEKKTWDQEKMREEESM----REREKKMREEEEMMREQEEKMQEQEEKMQE------ 745
Query: 553 HNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPRE 612
Q++ + +Q++K+ EQ++ + E ++ + E W EH K +E
Sbjct: 746 ------QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW--EH------------EKMQE 785
Query: 613 EEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECR 672
+E E R+ +R + +++ ++ EE+ + E
Sbjct: 786 QEKI--------------WEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 673 RILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKE 723
EK QEE+ Q + EE+ Q +E + +E + + + +E+++++ +E
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEE 882
Score = 52.4 bits (124), Expect = 2e-06
Identities = 61/344 (17%), Positives = 149/344 (43%), Gaps = 35/344 (10%)
Query: 559 QQQLIEKQKKKLQEQQKTILELK-KNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRT 617
Q++ I KQ++K+ Q++ + E + K + E W E L E + K E+
Sbjct: 284 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ--- 340
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAE 677
+ R ++ + +++ ++ EE+ + R E R E
Sbjct: 341 -----------------KELREQEEQMQEQEEKMWEQEEKMREQEEK-MWRQEERLWEQE 382
Query: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLE 737
K+ +++E+K+ + + E+ +R E++E E+++ ++++KM+E +K + ++ + +
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 738 AIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLAR 797
+ ER+ R+K + + + ++ +Q EE+ + + W Q+
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN----MWEQEEKEWQQQRLPEQKE 498
Query: 798 KMAQADQFYSQILLKRVIQSWLQYVIDLQE----EVRKFCVHFLQKKIFRAWFNMVREVK 853
K+ + ++ Q + I + + D +E E + + ++++ + W E
Sbjct: 499 KLWEQEKMQEQ---EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ--EEKM 553
Query: 854 IDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQ 897
D + K E +++ +TW + K +EER++E ++
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Score = 51.2 bits (121), Expect = 4e-06
Identities = 48/249 (19%), Positives = 107/249 (42%), Gaps = 13/249 (5%)
Query: 60 RNSDLPRSPWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTV 119
+ + + W Q ++ E++ + ++ E +E++ + QE +E+ +
Sbjct: 570 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE-------QEEKMQEQEEKMQEQ 622
Query: 120 SSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKEN 179
E + +K + + E+EE Q+ + K M E +E
Sbjct: 623 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682
Query: 180 QDK--KQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKR 237
++K +Q+K + T E K + ++R E+ + +R +K ++ + Q +E++
Sbjct: 683 EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR-EREKKMREEEEMMREQEEKMQEQEE 741
Query: 238 KALEAKKEEEEIQREMVKLRREIIERRR---TVKAAWKIEKKRQEENSQNSSEKVMFQST 294
K E ++E E + +M + ++ E++R + W+ EK +++E EK+ Q
Sbjct: 742 KMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEE 801
Query: 295 HILPDEEKM 303
+ EEKM
Sbjct: 802 KMRGQEEKM 810
Score = 50.8 bits (120), Expect = 6e-06
Identities = 56/256 (21%), Positives = 121/256 (47%), Gaps = 10/256 (3%)
Query: 79 EQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHL-KYDKF 137
E++++ +E E +E + + + +QE E+ + + + +PE L +++K
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQEEKMWEQE---EKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673
Query: 138 DDLCGYLEEEE---ESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEM 194
+ E+EE E ++K K M E+ +E + K ++++ + +
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 195 RHKQVKENRLRREKELEYQRIEKTLKKSAFL-EAQCLVQEEKKRKALEAKKEEEEIQREM 253
Q +E +++ ++E +++ EK ++ + E Q L ++++K E +E+E+I +
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Query: 254 VKLR-REIIERRRTVKAAWKIEKKR-QEENSQNSSEKVMFQSTHILPDEEKMVKERKRKL 311
K+R +E R + K + EK R QEE EK+ Q + EEKM + ++
Sbjct: 794 EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME 853
Query: 312 KEVLIQTFKENQQCQK 327
+++ Q K +Q +K
Sbjct: 854 EKMQGQEEKMREQEEK 869
Score = 48.5 bits (114), Expect = 3e-05
Identities = 49/243 (20%), Positives = 117/243 (48%), Gaps = 14/243 (5%)
Query: 662 EERAIQRAECRRILAEKKKKQEEEKL----AQLKAQEEERQKREAEEKEAQLERKREEKR 717
+E ++ E + E+K ++EE+L +++ QEE+ ++E +E + E + +EK
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 718 LKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSL 777
L++ KEL +Q+ + Q+ + +E +R++ + W++ +Q Q+ E+ +
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEE----KMREQEEKMWRQEERLWEQEKQMREQEQKM 392
Query: 778 FLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKR---VIQSWLQYVIDLQEEVRKFCV 834
Q + M +R +E +M + ++ + Q+ R +Q + D +E++++
Sbjct: 393 RDQEERMWEQDERLREK-EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Query: 835 HFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEE 894
++K R +RE + Q + E E ++ W R ++ K ++E+++E+
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKE--WQQQRLPEQKEKLWEQEKMQEQ 509
Query: 895 RRQ 897
+
Sbjct: 510 EEK 512
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/177 (20%), Positives = 83/177 (46%), Gaps = 30/177 (16%)
Query: 557 VFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPR 616
+++QQ + +QK+KL E +K + E +K + E W Q + K +E+E +
Sbjct: 654 MWEQQRLPEQKEKLWEHEK-MQEQEKMQEQEEKIWE----------QEKMEKKTQEQEKK 702
Query: 617 TCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILA 676
T + +R + K++ +++ EE+ ++ E +
Sbjct: 703 TWDQ---------------EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747
Query: 677 EKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRL----KKMKELEKQKR 729
E+ +QEE+ Q + E+++ E +EK + E+ +E++++ +KM++ E++ R
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMR 804
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/287 (16%), Positives = 124/287 (43%), Gaps = 31/287 (10%)
Query: 69 WGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEA 128
W Q+ ++ +++++ ++ + +E + + + +++ EEE + + E
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 129 NGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDP 188
+ ++ L E++E Q+ + K + D Q+KK +
Sbjct: 480 MWEQEEKEWQQQ--RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 537
Query: 189 RLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAK----- 243
++ + +E ++R +++ + + E+ KK+ E + QEEK R+ +
Sbjct: 538 KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597
Query: 244 -KEEEEIQREMVKLRREIIER-RRTVKAAWKIEKKRQEENSQN--------SSEKVMFQS 293
+EEEE+ RE + +E E+ + + W+ E+K QE+ + E+ M++
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 294 THI------------LPDEEKMVKERKRKLKEVLIQTFKENQQCQKR 328
+ + ++EKM ++ ++ ++ ++ K+ Q+ +K+
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME--KKTQEQEKK 702
Score = 35.4 bits (80), Expect = 0.25
Identities = 48/212 (22%), Positives = 84/212 (39%), Gaps = 29/212 (13%)
Query: 241 EAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDE 300
+A + EE+ +E L E+ T + K + QE+ SEK Q
Sbjct: 194 KADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLN------ 247
Query: 301 EKMVKERKRKLK-------EVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTL--- 350
VKE KRKL+ +V T +E Q+ K I K+ +
Sbjct: 248 ---VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLRE 304
Query: 351 SDWKIQLKVLRAWRDYTRFQKLERETQALENDLR--------EENRKQQLATEYNRKQVL 402
+ K++ + + WR R ++ E+E + E +LR EE ++Q + +++ +
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 403 RHCFTEWQHWHGAELLKRELALTKEETRKKMD 434
R E + W E L + +E+ +K D
Sbjct: 365 RE--QEEKMWRQEERLWEQEKQMREQEQKMRD 394
Score = 34.3 bits (77), Expect = 0.56
Identities = 43/188 (22%), Positives = 77/188 (40%), Gaps = 19/188 (10%)
Query: 564 EKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVN 623
EK +KK QEQ+K + +K + E + E + E + + + + + + +M
Sbjct: 690 EKMEKKTQEQEKKTWDQEK---MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 624 SPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAI-QRAECRRILAEKKKKQ 682
E + + +R P+Q K E+ I ++ E R EK + Q
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 683 EEEKLAQ---LKAQEEERQKRE------------AEEKEAQLERKREEKRLKKMKELEKQ 727
EE+ Q ++ QEE+ +E EEK E K EEK + +++ +Q
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ 866
Query: 728 KRIKRNQQ 735
+ R Q+
Sbjct: 867 EEKMRGQE 874
Score = 30.4 bits (67), Expect = 8.1
Identities = 28/147 (19%), Positives = 63/147 (42%), Gaps = 17/147 (11%)
Query: 146 EEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLR 205
E+EE Q+ + K M E E ++K + ++ ++ + + +E ++R
Sbjct: 759 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR 818
Query: 206 REKELEYQRIEKTLKKSAFL---EAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIE 262
++E + + EK + + E + QEEK + ++ ++E+ Q E ++ + E
Sbjct: 819 GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEE--- 875
Query: 263 RRRTVKAAWKIEKKRQEENSQNSSEKV 289
+ + QEE + EK+
Sbjct: 876 -----------KMREQEEKMRGQEEKI 891
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 66.6 bits (161), Expect = 1e-10
Identities = 55/265 (20%), Positives = 129/265 (48%), Gaps = 10/265 (3%)
Query: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFL-EAQCLVQE-E 234
+E ++K ++++ ++ + KE ++RR++E+ +++ EK ++ + E + ++E E
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 235 KKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQST 294
+K E +E+EE ++E K+R + + + K + EK R++E E+ M++
Sbjct: 445 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE 504
Query: 295 HILPDEEKMVKERKRKLKEVL---IQTFKENQQC--QKRYFAAWHKLILDHRIKLGKAGT 349
+ ++EK+ +E KR+ +E + + +E ++ QK + I K+ +
Sbjct: 505 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 350 L---SDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCF 406
+ KI+ + + WR + ++ E + + E +RE+ Q E +Q + C
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 624
Query: 407 TEWQHWHGAELLKRELALTKEETRK 431
E + E ++R+ +E+ +K
Sbjct: 625 QEEKMQEQEEKMRRQEEKIREQEKK 649
Score = 62.4 bits (150), Expect = 2e-09
Identities = 65/346 (18%), Positives = 149/346 (43%), Gaps = 28/346 (8%)
Query: 79 EQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFD 138
E+I++ +E E +E + + + +QE E+ + + E + +
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 139 DLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQ 198
+ + E EE Q+ I K + + E Q+K+Q+++ ++ + +
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-------QEKRQEQEAKMWRQEEKIR 487
Query: 199 VKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRR 258
+E ++R ++E +++ EK ++ E + ++E+ + E +E+EEI R+ K+
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 259 EIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQT 318
+ + R+ + W RQEE + EK+ Q + EEK ++E++ K++E
Sbjct: 548 QEEKIRKQEEKMW-----RQEEKMHDQEEKIREQEEKVWRQEEK-IREQEEKIRE----- 596
Query: 319 FKENQQCQKRYFAAWHKLILDHRIKLGKAGTL---SDWKIQLKVLRAWRDYTRFQKLERE 375
Q+ ++ + K+G+ + K+Q + + R + ++ E++
Sbjct: 597 -------QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK 649
Query: 376 TQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRE 421
+ E +RE+ Q E +Q + C E + E ++R+
Sbjct: 650 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Score = 59.7 bits (143), Expect = 1e-08
Identities = 76/397 (19%), Positives = 176/397 (44%), Gaps = 46/397 (11%)
Query: 518 KQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTI 577
K+ +++ A+ Q NE +Q+ E + Q++ I++ ++K+QEQ++ I
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQE--------EKMWRQEEKIQEWEEKIQEQEEKI 384
Query: 578 LELKKNL--------QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASP 629
E ++ + + E W E + Q ++ + E+ R +M+
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKM---RRQEEMMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 630 GTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQ 689
E + + + R+ ++ ++ E+R Q A+ R E+K +++EEK+
Sbjct: 442 ELEEKMHEQEKI----REQEEKRQEEEKIREQEKRQEQEAKMWR--QEEKIREQEEKI-- 493
Query: 690 LKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKE--HYERV 747
+E+E + EEK + E+ REE++ ++ +E+ +Q+ R Q+ KE H +
Sbjct: 494 ---REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEE 550
Query: 748 LLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQ--RSQESLARKMAQADQF 805
+RK+ + W++ Q ++ E+ ++ Q + + + R QE R+ + Q
Sbjct: 551 KIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610
Query: 806 YSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAE 865
+ + ++ + + +QE+ K Q++ R +RE + + + E+ E
Sbjct: 611 QEEKMGEQE-EKMCEQEEKMQEQEEKM---RRQEEKIREQEKKIREQEEKIREQEEMMQE 666
Query: 866 HSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRK 902
+ + W++ K ++E +E+ +++RR+
Sbjct: 667 QEE--------KMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Score = 50.1 bits (118), Expect = 1e-05
Identities = 49/227 (21%), Positives = 101/227 (44%), Gaps = 24/227 (10%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
Q++ + +Q++K+ EQ+K E K+ Q E W E + E K E+E +
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIWRQKEKIHEQEEKI- 552
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
R + R+ +++ ++ EE+ ++ E R EK
Sbjct: 553 -------------------RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK 593
Query: 679 KKKQEEEKLAQLK-AQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLE 737
++QEE+ Q + QE+E + E EEK + E K +E+ +KM+ E++ R + + E
Sbjct: 594 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE-EKMRRQEEKIREQEKKIRE 652
Query: 738 AIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYM 784
K + +++++ + W++ +Q ++ E+ + Q + M
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Score = 49.7 bits (117), Expect = 1e-05
Identities = 59/267 (22%), Positives = 116/267 (43%), Gaps = 30/267 (11%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQS-------------- 604
+Q+ I +Q++K QE++K I E +K + W E + E +
Sbjct: 449 EQEKIREQEEKRQEEEK-IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Query: 605 HLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEER 664
H K REEE R Q + + + + R+ +++ ++ EE+
Sbjct: 508 HEQEKIREEEKRQEQEEMWR---------QEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558
Query: 665 AIQRAECRRILAEKKKKQEEEKLAQ-LKAQEEERQKREAEEKEAQLERKREEKRLKKMKE 723
++ E EK ++QEE+ Q K +E+E + RE EEK + E +E+ K ++
Sbjct: 559 MWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQ 618
Query: 724 LEK--QKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQR 781
EK ++ K +Q E + ++ + KK E +++R Q + + E+ ++ Q
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE---MMQEQEEKMWEQE 675
Query: 782 KYMLTWFQRSQESLARKMAQADQFYSQ 808
+ M ++ QE + Q ++ + Q
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Score = 47.4 bits (111), Expect = 6e-05
Identities = 52/295 (17%), Positives = 129/295 (43%), Gaps = 32/295 (10%)
Query: 148 EESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRRE 207
EE T + + L++N + +++ K + + + + +++ K++K R +
Sbjct: 257 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 316
Query: 208 KELEYQRIEKTLKKSAFLEAQCLVQEEKKRKA-LEAKKEEEEIQREMVKLRREIIERRRT 266
L Q+++ EA L +E + A L+A+ EE E+ + + + E + R+
Sbjct: 317 LLLPQQQLQA--------EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 368
Query: 267 VKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQ 326
W+ + + QEE + EK+ Q + EE M+ E++ K++ +++ ++ +
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE-MMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 327 KRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREE 386
++ W K + +I+ ++ + + ++ E + Q E +E
Sbjct: 428 RQEEMMWEK---EEKIR--------------ELEEKMHEQEKIREQEEKRQEEEKIREQE 470
Query: 387 NRKQQLATEYNRKQVLRH-----CFTEWQHWHGAELLKRELALTKEETRKKMDAL 436
R++Q A + +++ +R E + W E + + + +EE R++ + +
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM 525
Score = 46.6 bits (109), Expect = 1e-04
Identities = 52/218 (23%), Positives = 95/218 (43%), Gaps = 34/218 (15%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
+Q+ I +QK+K+ EQ++ I + + E W E + E K RE+E +
Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQE------EKMWRQEEKMHDQE------EKIREQEEKVW 581
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
+ E R +R + + + EE+ ++ E + EK
Sbjct: 582 RQ------EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK 635
Query: 679 KKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEK--QKRIKRNQQL 736
++QEE K +E+E++ RE EEK + E +E+ K ++ EK ++ K +Q
Sbjct: 636 MRRQEE------KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 689
Query: 737 EAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEH 774
E + ++ +K E RLR Q ++ +Q +EH
Sbjct: 690 EKMRRQ-------EEKMWEQEVRLR-QQEEKMQEHQEH 719
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/145 (22%), Positives = 71/145 (48%), Gaps = 13/145 (8%)
Query: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKT---LKKSAFLEAQCLVQE 233
+E ++K +++ ++ + + +E ++R ++E+ ++ EK +K E + QE
Sbjct: 574 REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633
Query: 234 EKKRKALEAKKEEEE-IQREMVKLRREIIERRRTVKAAWKIEKK---------RQEENSQ 283
EK R+ E +E+E+ I+ + K+R + + + W+ E+K QEE +
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Query: 284 NSSEKVMFQSTHILPDEEKMVKERK 308
EK+ Q + EEKM + ++
Sbjct: 694 RQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 44.3 bits (103), Expect = 5e-04
Identities = 65/348 (18%), Positives = 151/348 (43%), Gaps = 43/348 (12%)
Query: 563 IEKQKKKLQEQ-QKTILELKKNLQLAEAQWAAEHALAVTEAQ-SHLLSKPREEEPRTCQM 620
++ KLQ Q ++ L + N Q E W E + E + K RE+E +
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI--- 391
Query: 621 LVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKK 680
E R + K +++ ++ EE+ ++ E EK +
Sbjct: 392 ----------REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 681 KQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIA 740
+ EE+ Q K +E+E +++E E+ Q +R+ +E ++ + +E +++ K +Q E +
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 741 KEHYERVLLRKKGLEPWKRLRMQS--KQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARK 798
++ E++ ++K E KR + +Q ++ E+ ++ Q++ + ++ ++ +
Sbjct: 502 RQE-EKIHEQEKIREEEKRQEQEEMWRQEEKIREQE-EIWRQKEKIHEQEEKIRKQEEKM 559
Query: 799 MAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQG 858
Q ++ + Q + I+ + V +E++R+ Q++ R +RE + +Q
Sbjct: 560 WRQEEKMHDQ---EEKIREQEEKVWRQEEKIRE------QEEKIREQEEKIREQEEMTQE 610
Query: 859 KHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVEI 906
+ E E + K ++E +E+ +++RR+ +I
Sbjct: 611 QEEKMGEQEE---------------KMCEQEEKMQEQEEKMRRQEEKI 643
Score = 43.5 bits (101), Expect = 0.001
Identities = 40/192 (20%), Positives = 94/192 (48%), Gaps = 22/192 (11%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQ-WAAEHALAVTEAQSHLLSKPREEEPRT 617
Q++ I KQ++K+ Q++ + + ++ ++ E + W E + E + + +EE+ R
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI----REQEEKIRE 603
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAE 677
+ + G + + + +++ ++ EE+ R + ++I +
Sbjct: 604 QEEMTQEQEEKMGEQEEK--------MCEQEEKMQEQEEKMRRQEEKI--REQEKKIREQ 653
Query: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEK--QKRIKRNQQ 735
++K +E+E++ QE+E + E EEK + E K +E+ K ++ EK ++ ++ QQ
Sbjct: 654 EEKIREQEEM----MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709
Query: 736 LEAIAKEHYERV 747
E + +EH E +
Sbjct: 710 EEKM-QEHQEHL 720
Score = 36.2 bits (82), Expect = 0.15
Identities = 35/168 (20%), Positives = 78/168 (46%), Gaps = 23/168 (13%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
Q++ + +Q++K++EQ++ I E ++ ++ E +T+ Q K E+E + C
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQEE---------MTQEQEE---KMGEQEEKMC 623
Query: 619 QMLVNSPVASPGTEGRSDS-RNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAE 677
+ + + R +R + +++ +++ EE+ ++ E E
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Query: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELE 725
K ++QEE+ RQ+ + E+E +L R++EEK + + LE
Sbjct: 684 KMQEQEEKM---------RRQEEKMWEQEVRL-RQQEEKMQEHQEHLE 721
Score = 35.0 bits (79), Expect = 0.33
Identities = 47/274 (17%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 662 EERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKM 721
E A+ R + +++ K++ KL +E+ Q E+E+ E QL K +++L++
Sbjct: 262 ERDALSLELYRNTITDEELKEKNAKL------QEKLQLVESEKSEIQLNVKELKRKLERA 315
Query: 722 KEL----------------------EKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR 759
K L + Q +++ N+ + ++ E++ +++ ++ W+
Sbjct: 316 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 375
Query: 760 LRMQSKQNIQVAEE---HYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQ 816
+ ++ I+ EE ++R+ + W +E R+ + + + ++
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMW---EKEEKMRRQEEMMWEKEEKMRRQEEM 432
Query: 817 SW--LQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGK----------HEIAA 864
W + + +L+E++ + Q+KI E KI Q K E
Sbjct: 433 MWEKEEKIRELEEKMHE------QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 865 EHSDRRILWITLRTWKKFVKFMKEERVKEERRQQ 898
+ +I + W++ K ++E+++EE ++Q
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQ 520
Score = 34.7 bits (78), Expect = 0.43
Identities = 37/201 (18%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 69 WGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEA 128
W Q ++ E+I E E +E + + +QE ++ + E
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 129 NGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDP 188
+ +K + + E+EE T Q+ + M E + + Q++K ++
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEE-----KMGEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 189 RLTMEMRHK-QVKENRLRREKELEYQRIEKTLKKSAFL--EAQCLVQEEKKRKALEAKKE 245
E K + +E ++R ++E+ ++ EK ++ + + + + ++E+K + E K
Sbjct: 641 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 700
Query: 246 EEEI----QREMVKLRREIIE 262
E+E+ Q E ++ +E +E
Sbjct: 701 EQEVRLRQQEEKMQEHQEHLE 721
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 65.9 bits (159), Expect = 2e-10
Identities = 45/123 (36%), Positives = 77/123 (62%), Gaps = 10/123 (8%)
Query: 663 ERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKRE---EKRLK 719
ER E RR +++++E+E+LAQL+ E+ER++RE +E+ ERKR+ EK+L+
Sbjct: 359 ERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQ----ERKRQLELEKQLE 414
Query: 720 KMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFL 779
K +ELE+Q+ +R +++E +E +R L R++ LE W+R R Q N + E+ + L
Sbjct: 415 KQRELERQREEERRKEIE--RREAAKRELERQRQLE-WERNRRQELLNQRNKEQEDIVVL 471
Query: 780 QRK 782
+ K
Sbjct: 472 KAK 474
Score = 49.3 bits (116), Expect = 2e-05
Identities = 73/286 (25%), Positives = 134/286 (46%), Gaps = 41/286 (14%)
Query: 180 QDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQ-RIEKTLKKSAFLEAQCLVQEEKKRK 238
Q +K+Q+ RL R +Q ++ R R+E+E + Q +EK L+K LE Q +EE++RK
Sbjct: 375 QQRKEQE--RLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQ---REEERRK 429
Query: 239 ALE---AKKEEEEIQREMV---KLRREIIERRRTVK---AAWKIEKKRQEENSQNSSEK- 288
+E A K E E QR++ R+E++ +R + K +KK E + ++K
Sbjct: 430 EIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKK 489
Query: 289 ---------VMFQSTHILPDEEKMVKERKRKLKEV--LIQTFKENQQCQKRYFAAWHKLI 337
+ + T + E K R+ ++ E+ L Q +E+QQ R K I
Sbjct: 490 HQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIP--EKQI 547
Query: 338 LDHRIKLGKAGTL-SDWKIQLKVLRAWRDYTRFQKLERETQALENDLREE--------NR 388
L+ ++K + +L D + LK ++ R Q L + +E + R + N+
Sbjct: 548 LNDQLKQVQQNSLHRDSLVTLKRALEAKELAR-QHLRDQLDEVEKETRSKLQEIDIFNNQ 606
Query: 389 KQQLATEYNRKQVLRHCFTEWQHWHGAELLKR--ELALTKEETRKK 432
++L +N++Q+ + E + E ++ EL KEE +++
Sbjct: 607 LKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRR 652
Score = 48.1 bits (113), Expect = 4e-05
Identities = 70/302 (23%), Positives = 137/302 (45%), Gaps = 58/302 (19%)
Query: 666 IQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELE 725
++RAE R +++++QE+E+ QL+ +++ ++RE E + + RK E+R +ELE
Sbjct: 386 LERAEQER---KERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442
Query: 726 KQKRI-----KRNQQLEAIAKEHYERVLL--RKKGLE------PWKRLRMQSK------- 765
+Q+++ +R + L KE + V+L +KK LE K+ +++ K
Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCR 502
Query: 766 -----QNIQVAEEHYSL-FLQRKYMLTWFQRSQESLAR------------KMAQADQFY- 806
Q I+ + L + ++ Q SQ+ L R K Q + +
Sbjct: 503 LTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHR 562
Query: 807 -SQILLKRVIQS---WLQYVIDLQEEVRKFCVHFLQK-KIFRAWFNMVREV--KIDSQGK 859
S + LKR +++ Q++ D +EV K LQ+ IF +RE+ K Q +
Sbjct: 563 DSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQ 622
Query: 860 HEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVEIL---PDFQVPGRY 916
+ AE ++ +K ++ K++ + R Q+ ++ +E + + Q P +
Sbjct: 623 KSMEAERLKQK------EQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKL 676
Query: 917 HE 918
HE
Sbjct: 677 HE 678
Score = 45.1 bits (105), Expect = 3e-04
Identities = 63/277 (22%), Positives = 120/277 (43%), Gaps = 47/277 (16%)
Query: 180 QDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQR---IEKTLKKSAFLEAQCLVQEEKK 236
+D++QQ + +L + K+ +EN R ELE +R +E+ K+ L ++E+K
Sbjct: 336 EDEQQQLEKKLPVTFEDKK-RENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERK 394
Query: 237 ---------RKALEAKKE---EEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQN 284
++ LE +K+ + E++R+ + RR+ IERR K ++E++RQ E +N
Sbjct: 395 ERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKR--ELERQRQLEWERN 452
Query: 285 SSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKL 344
++++ Q E+ +V + K+K E ++ + + H+L
Sbjct: 453 RRQELLNQRNK--EQEDIVVLKAKKKTLEFELEALNDKK----------HQL-------- 492
Query: 345 GKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRH 404
G L D + +L R + T + R + + + +Q L KQ+L
Sbjct: 493 --EGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILND 550
Query: 405 CFTEWQ----HWHGAELLKREL---ALTKEETRKKMD 434
+ Q H LKR L L ++ R ++D
Sbjct: 551 QLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLD 587
Score = 45.1 bits (105), Expect = 3e-04
Identities = 40/188 (21%), Positives = 82/188 (43%), Gaps = 13/188 (6%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQ---------LAEAQWAAEHALAVTEAQSHLLSK 609
Q+Q IE K + + I L++ LQ + E Q + V + H S
Sbjct: 506 QRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSL 565
Query: 610 PREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRA 669
+ + L + E ++R+ L + QL I + + +
Sbjct: 566 VTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSM 625
Query: 670 ECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKR 729
E R+ K+K++E K+ +L+ Q+EE Q+R E + LE ++E ++ ++L ++++
Sbjct: 626 EAERL----KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEK 681
Query: 730 IKRNQQLE 737
+KR + ++
Sbjct: 682 LKREESVK 689
Score = 44.3 bits (103), Expect = 5e-04
Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 9/146 (6%)
Query: 172 EDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLV 231
++L R+ +D+ + + +++ + N+L+ +E+ ++ L+K +EA+ L
Sbjct: 575 KELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQ---QLQKQKSMEAERLK 631
Query: 232 QEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMF 291
Q+E++RK +E +K++EE QR + ++ +E + + K +EE +
Sbjct: 632 QKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKRE------ 685
Query: 292 QSTHILPDEEKMVKERKRKLKEVLIQ 317
+S EEK +E + KL + Q
Sbjct: 686 ESVKKKDGEEKGKQEAQDKLGRLFHQ 711
Score = 42.0 bits (97), Expect = 0.003
Identities = 49/189 (25%), Positives = 90/189 (47%), Gaps = 37/189 (19%)
Query: 555 RHVFQQQLIEKQKKKLQEQ---QKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPR 611
R + ++Q++ Q K++Q+ + +++ LK+ L+ E A+ HL +
Sbjct: 540 RLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKEL------------ARQHLRDQLD 587
Query: 612 EEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRR--KPKQLMTPHPILKAMEERAIQRA 669
E E T L + + N L LR +QL K+ME +++
Sbjct: 588 EVEKETRSKLQEIDIFN----------NQLKELREIHNKQQLQKQ----KSMEAERLKQK 633
Query: 670 ECRRILAEKKKKQEEEKLAQLKAQEEERQKRE--AEEKEAQLERK-REEKRLKKMKELEK 726
E R + E +K++EE AQ +AQE ++Q E +E E Q RK EE++LK+ + ++K
Sbjct: 634 EQERKIIELEKQKEE---AQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKK 690
Query: 727 QKRIKRNQQ 735
+ ++ +Q
Sbjct: 691 KDGEEKGKQ 699
Score = 37.0 bits (84), Expect = 0.086
Identities = 66/373 (17%), Positives = 147/373 (39%), Gaps = 40/373 (10%)
Query: 563 IEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLV 622
+EK+++ L EQQ+ K+ +LA+ + A+ + R+E+ R Q+ +
Sbjct: 365 LEKRRQALLEQQR-----KEQERLAQLE----------RAEQERKERERQEQERKRQLEL 409
Query: 623 NSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQ 682
+ + R R R++ ++ L+ + +R + +L ++ K+Q
Sbjct: 410 EKQL----EKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQ 465
Query: 683 EEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKE 742
E+ + + K + E + +K+ QLE K ++ R + + ++ + ++++L
Sbjct: 466 EDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEIT 525
Query: 743 HYERVLLRKK----GLEPWKRLRMQSKQNIQVAEEHYSLF-----------LQRKYMLTW 787
H ++ L + L P K++ + +Q H L R+++
Sbjct: 526 HLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQ 585
Query: 788 FQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFN 847
++ K+ + D F +Q+ R I + Q E + ++KI
Sbjct: 586 LDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIEL-EK 644
Query: 848 MVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVK-----EERRQQLRRK 902
E + +Q + + EH + R + K +EE VK E+ +Q+ + K
Sbjct: 645 QKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDK 704
Query: 903 VVEILPDFQVPGR 915
+ + Q P +
Sbjct: 705 LGRLFHQHQEPAK 717
Score = 33.9 bits (76), Expect = 0.73
Identities = 42/185 (22%), Positives = 89/185 (48%), Gaps = 24/185 (12%)
Query: 650 QLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEER----QKREAEEK 705
Q + P+L+ + Q+ E + + + KK+E + L+ ++ + Q+R+ +E+
Sbjct: 327 QRLPEEPVLEDEQ----QQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER 382
Query: 706 EAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSK 765
AQLER +E+ K+ + E++ R +QLE E+ L +++ LE R R + +
Sbjct: 383 LAQLERAEQER--KERERQEQE----RKRQLE------LEKQLEKQRELE---RQREEER 427
Query: 766 QNIQVAEEHYSLFLQRKYMLTWFQ-RSQESLARKMAQADQFYSQILLKRVIQSWLQYVID 824
+ E L+R+ L W + R QE L ++ + + K+ ++ L+ + D
Sbjct: 428 RKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALND 487
Query: 825 LQEEV 829
+ ++
Sbjct: 488 KKHQL 492
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 65.9 bits (159), Expect = 2e-10
Identities = 45/123 (36%), Positives = 77/123 (62%), Gaps = 10/123 (8%)
Query: 663 ERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKRE---EKRLK 719
ER E RR +++++E+E+LAQL+ E+ER++RE +E+ ERKR+ EK+L+
Sbjct: 359 ERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQ----ERKRQLELEKQLE 414
Query: 720 KMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFL 779
K +ELE+Q+ +R +++E +E +R L R++ LE W+R R Q N + E+ + L
Sbjct: 415 KQRELERQREEERRKEIE--RREAAKRELERQRQLE-WERNRRQELLNQRNKEQEDIVVL 471
Query: 780 QRK 782
+ K
Sbjct: 472 KAK 474
Score = 49.3 bits (116), Expect = 2e-05
Identities = 73/286 (25%), Positives = 134/286 (46%), Gaps = 41/286 (14%)
Query: 180 QDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQ-RIEKTLKKSAFLEAQCLVQEEKKRK 238
Q +K+Q+ RL R +Q ++ R R+E+E + Q +EK L+K LE Q +EE++RK
Sbjct: 375 QQRKEQE--RLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQ---REEERRK 429
Query: 239 ALE---AKKEEEEIQREMV---KLRREIIERRRTVK---AAWKIEKKRQEENSQNSSEK- 288
+E A K E E QR++ R+E++ +R + K +KK E + ++K
Sbjct: 430 EIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKK 489
Query: 289 ---------VMFQSTHILPDEEKMVKERKRKLKEV--LIQTFKENQQCQKRYFAAWHKLI 337
+ + T + E K R+ ++ E+ L Q +E+QQ R K I
Sbjct: 490 HQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIP--EKQI 547
Query: 338 LDHRIKLGKAGTL-SDWKIQLKVLRAWRDYTRFQKLERETQALENDLREE--------NR 388
L+ ++K + +L D + LK ++ R Q L + +E + R + N+
Sbjct: 548 LNDQLKQVQQNSLHRDSLVTLKRALEAKELAR-QHLRDQLDEVEKETRSKLQEIDIFNNQ 606
Query: 389 KQQLATEYNRKQVLRHCFTEWQHWHGAELLKR--ELALTKEETRKK 432
++L +N++Q+ + E + E ++ EL KEE +++
Sbjct: 607 LKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELEKQKEEAQRR 652
Score = 48.1 bits (113), Expect = 4e-05
Identities = 70/302 (23%), Positives = 137/302 (45%), Gaps = 58/302 (19%)
Query: 666 IQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELE 725
++RAE R +++++QE+E+ QL+ +++ ++RE E + + RK E+R +ELE
Sbjct: 386 LERAEQER---KERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE 442
Query: 726 KQKRI-----KRNQQLEAIAKEHYERVLL--RKKGLE------PWKRLRMQSK------- 765
+Q+++ +R + L KE + V+L +KK LE K+ +++ K
Sbjct: 443 RQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCR 502
Query: 766 -----QNIQVAEEHYSL-FLQRKYMLTWFQRSQESLAR------------KMAQADQFY- 806
Q I+ + L + ++ Q SQ+ L R K Q + +
Sbjct: 503 LTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHR 562
Query: 807 -SQILLKRVIQS---WLQYVIDLQEEVRKFCVHFLQK-KIFRAWFNMVREV--KIDSQGK 859
S + LKR +++ Q++ D +EV K LQ+ IF +RE+ K Q +
Sbjct: 563 DSLVTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQ 622
Query: 860 HEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVEIL---PDFQVPGRY 916
+ AE ++ +K ++ K++ + R Q+ ++ +E + + Q P +
Sbjct: 623 KSMEAERLKQK------EQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKL 676
Query: 917 HE 918
HE
Sbjct: 677 HE 678
Score = 45.1 bits (105), Expect = 3e-04
Identities = 63/277 (22%), Positives = 120/277 (43%), Gaps = 47/277 (16%)
Query: 180 QDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQR---IEKTLKKSAFLEAQCLVQEEKK 236
+D++QQ + +L + K+ +EN R ELE +R +E+ K+ L ++E+K
Sbjct: 336 EDEQQQLEKKLPVTFEDKK-RENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERK 394
Query: 237 ---------RKALEAKKE---EEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQN 284
++ LE +K+ + E++R+ + RR+ IERR K ++E++RQ E +N
Sbjct: 395 ERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKR--ELERQRQLEWERN 452
Query: 285 SSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKL 344
++++ Q E+ +V + K+K E ++ + + H+L
Sbjct: 453 RRQELLNQRNK--EQEDIVVLKAKKKTLEFELEALNDKK----------HQL-------- 492
Query: 345 GKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRH 404
G L D + +L R + T + R + + + +Q L KQ+L
Sbjct: 493 --EGKLQDIRCRLTTQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILND 550
Query: 405 CFTEWQ----HWHGAELLKREL---ALTKEETRKKMD 434
+ Q H LKR L L ++ R ++D
Sbjct: 551 QLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQLD 587
Score = 45.1 bits (105), Expect = 3e-04
Identities = 40/188 (21%), Positives = 82/188 (43%), Gaps = 13/188 (6%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQ---------LAEAQWAAEHALAVTEAQSHLLSK 609
Q+Q IE K + + I L++ LQ + E Q + V + H S
Sbjct: 506 QRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSL 565
Query: 610 PREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRA 669
+ + L + E ++R+ L + QL I + + +
Sbjct: 566 VTLKRALEAKELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSM 625
Query: 670 ECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKR 729
E R+ K+K++E K+ +L+ Q+EE Q+R E + LE ++E ++ ++L ++++
Sbjct: 626 EAERL----KQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEK 681
Query: 730 IKRNQQLE 737
+KR + ++
Sbjct: 682 LKREESVK 689
Score = 44.3 bits (103), Expect = 5e-04
Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 9/146 (6%)
Query: 172 EDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLV 231
++L R+ +D+ + + +++ + N+L+ +E+ ++ L+K +EA+ L
Sbjct: 575 KELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQ---QLQKQKSMEAERLK 631
Query: 232 QEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMF 291
Q+E++RK +E +K++EE QR + ++ +E + + K +EE +
Sbjct: 632 QKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKRE------ 685
Query: 292 QSTHILPDEEKMVKERKRKLKEVLIQ 317
+S EEK +E + KL + Q
Sbjct: 686 ESVKKKDGEEKGKQEAQDKLGRLFHQ 711
Score = 42.0 bits (97), Expect = 0.003
Identities = 49/189 (25%), Positives = 90/189 (47%), Gaps = 37/189 (19%)
Query: 555 RHVFQQQLIEKQKKKLQEQ---QKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPR 611
R + ++Q++ Q K++Q+ + +++ LK+ L+ E A+ HL +
Sbjct: 540 RLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKEL------------ARQHLRDQLD 587
Query: 612 EEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRR--KPKQLMTPHPILKAMEERAIQRA 669
E E T L + + N L LR +QL K+ME +++
Sbjct: 588 EVEKETRSKLQEIDIFN----------NQLKELREIHNKQQLQKQ----KSMEAERLKQK 633
Query: 670 ECRRILAEKKKKQEEEKLAQLKAQEEERQKRE--AEEKEAQLERK-REEKRLKKMKELEK 726
E R + E +K++EE AQ +AQE ++Q E +E E Q RK EE++LK+ + ++K
Sbjct: 634 EQERKIIELEKQKEE---AQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKK 690
Query: 727 QKRIKRNQQ 735
+ ++ +Q
Sbjct: 691 KDGEEKGKQ 699
Score = 37.0 bits (84), Expect = 0.086
Identities = 66/373 (17%), Positives = 147/373 (39%), Gaps = 40/373 (10%)
Query: 563 IEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLV 622
+EK+++ L EQQ+ K+ +LA+ + A+ + R+E+ R Q+ +
Sbjct: 365 LEKRRQALLEQQR-----KEQERLAQLE----------RAEQERKERERQEQERKRQLEL 409
Query: 623 NSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQ 682
+ + R R R++ ++ L+ + +R + +L ++ K+Q
Sbjct: 410 EKQL----EKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQ 465
Query: 683 EEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKE 742
E+ + + K + E + +K+ QLE K ++ R + + ++ + ++++L
Sbjct: 466 EDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEIT 525
Query: 743 HYERVLLRKK----GLEPWKRLRMQSKQNIQVAEEHYSLF-----------LQRKYMLTW 787
H ++ L + L P K++ + +Q H L R+++
Sbjct: 526 HLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQ 585
Query: 788 FQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFN 847
++ K+ + D F +Q+ R I + Q E + ++KI
Sbjct: 586 LDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIEL-EK 644
Query: 848 MVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVK-----EERRQQLRRK 902
E + +Q + + EH + R + K +EE VK E+ +Q+ + K
Sbjct: 645 QKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDK 704
Query: 903 VVEILPDFQVPGR 915
+ + Q P +
Sbjct: 705 LGRLFHQHQEPAK 717
Score = 33.9 bits (76), Expect = 0.73
Identities = 42/185 (22%), Positives = 89/185 (48%), Gaps = 24/185 (12%)
Query: 650 QLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEER----QKREAEEK 705
Q + P+L+ + Q+ E + + + KK+E + L+ ++ + Q+R+ +E+
Sbjct: 327 QRLPEEPVLEDEQ----QQLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQER 382
Query: 706 EAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSK 765
AQLER +E+ K+ + E++ R +QLE E+ L +++ LE R R + +
Sbjct: 383 LAQLERAEQER--KERERQEQE----RKRQLE------LEKQLEKQRELE---RQREEER 427
Query: 766 QNIQVAEEHYSLFLQRKYMLTWFQ-RSQESLARKMAQADQFYSQILLKRVIQSWLQYVID 824
+ E L+R+ L W + R QE L ++ + + K+ ++ L+ + D
Sbjct: 428 RKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALND 487
Query: 825 LQEEV 829
+ ++
Sbjct: 488 KKHQL 492
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 64.7 bits (156), Expect = 4e-10
Identities = 104/595 (17%), Positives = 241/595 (40%), Gaps = 83/595 (13%)
Query: 155 KFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQR 214
++I+ L + D+ +E ++ ++K+ L ++R + +++ + +L +
Sbjct: 159 RYIEELTKER--DALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEI----QLNVKE 212
Query: 215 IEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIE 274
+++ L+++ FL L Q + E ++EEE++ + K+R++ + W+ E
Sbjct: 213 LKRKLERAKFL----LPQVQTNTLQEEMWRQEEELREQEKKIRKQ-------EEKMWRQE 261
Query: 275 KK-RQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAW 333
++ R++E E+ M + L ++EK ++E++++L+E + ++ +Q Q++ W
Sbjct: 262 ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK-KLREQEEQMQEQEEKMW 320
Query: 334 HKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLA 393
+ + K++ + + WR R + E++ + E +R++ +
Sbjct: 321 EQ----------------EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364
Query: 394 TEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGI 453
E R++ R E + W E ++ E + + E + + + K+
Sbjct: 365 DERLREKEERMREQE-KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ------- 416
Query: 454 SLPEEATAMVGPPVKNGQETAVP----PLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQN 509
++ M K Q+ +P LWE+ + + + +
Sbjct: 417 ---KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 473
Query: 510 VSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKK 569
+ + + + Q E +R QK + R Q + + +++++
Sbjct: 474 KMW------RQEKMREQEDQMWEQEEKMRDQEQK-----MWDQEERMWEQDERLREKEER 522
Query: 570 LQEQQK------TILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVN 623
++EQ+K + E KK + + W E + E K REEE +M+
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE----EMM-- 576
Query: 624 SPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQE 683
E + +R + +++ ++ EE+ ++ E E+ K QE
Sbjct: 577 -------REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629
Query: 684 EEKL---AQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQ 735
+E++ + K QE+E + E EEK + E K E+ K + EK + + Q
Sbjct: 630 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Score = 64.7 bits (156), Expect = 4e-10
Identities = 79/370 (21%), Positives = 165/370 (44%), Gaps = 69/370 (18%)
Query: 558 FQQQLIEKQKKKL------QEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPR 611
+QQQ + +QK+KL QEQ++ I E ++ ++ E W E + E K R
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE-------KMR 482
Query: 612 EEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAEC 671
E+E + + +R + +++ + +ER ++ E
Sbjct: 483 EQEDQMWEQEEK--------------------MRDQEQKMWDQEERMWEQDERLREKEE- 521
Query: 672 RRILAEKKKKQEEEKLAQ-LKAQEEERQKREAEEKEAQLERKRE-EKRLKKMKELEKQKR 729
R+ +KK Q+EEK+ + K QE+E++ + EEK + ER RE EK++++ +E+ +++
Sbjct: 522 -RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 730 IKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQ 789
K +Q E + +E E++ +++ ++ + + ++ + EE + Q + M +
Sbjct: 581 EKMQEQEEKM-REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
Query: 790 RSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMV 849
+ QE + Q ++ Q +E++R+ Q++ + +
Sbjct: 640 KMQEQEEKMWEQEEKMREQ-----------------EEKMRE------QEEKMQGQEEKM 676
Query: 850 REVKIDSQGKHEIAAEHSDR------RILWITLRTWKKFVKF--MKEERVKEERRQQLRR 901
RE + QG+ E E ++ ++ + W + K +E R KEER + +
Sbjct: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE 736
Query: 902 KVVEILPDFQ 911
K+ E LP+ +
Sbjct: 737 KMQERLPEHE 746
Score = 60.8 bits (146), Expect = 6e-09
Identities = 86/376 (22%), Positives = 152/376 (40%), Gaps = 34/376 (9%)
Query: 69 WGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEA 128
W Q ++ E+I + ++ E +E + + + KQE E + + +PE
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE---ENMWEQEEKEWQQQRLPEQ 438
Query: 129 NGHL-KYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKD 187
L + +K + + E+EE Q+ + K M E + Q++K +
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498
Query: 188 PRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQE-EKKRKALEAKKEE 246
+ + + +++ REKE + +K ++ + + QE EKK E K E
Sbjct: 499 EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558
Query: 247 EEIQREMVKLRREIIE--RRRTVKAAWKIEKKR-QEENSQNSSEKVMFQSTHILPDEEKM 303
EE RE K RE E R + K + EK R QEE EK+ Q + EEKM
Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618
Query: 304 -VKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRA 362
+E + K++E +++ ++ Q++ W Q + +R
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE---------------------QEEKMRE 657
Query: 363 WRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELL--KR 420
+ R Q E + Q E +RE+ K Q E R+Q + E + W E + +
Sbjct: 658 QEEKMREQ--EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQE 715
Query: 421 ELALTKEETRKKMDAL 436
E +EE R+K + +
Sbjct: 716 EKMWGQEEMREKEERI 731
Score = 59.3 bits (142), Expect = 2e-08
Identities = 99/588 (16%), Positives = 242/588 (41%), Gaps = 57/588 (9%)
Query: 147 EEESTTVQKFIDHLLHK---------NVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHK 197
E E + +Q + L K V + + E++ R+E + ++Q+K R E +
Sbjct: 200 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 259
Query: 198 QVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLR 257
Q E RLR E+E + + E+ +++ QE++ R+ + +E+E+ RE KLR
Sbjct: 260 Q--EERLR-EQEGKMREQEEKMRR----------QEKRLREQEKELREQEKELREQKKLR 306
Query: 258 REIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQ 317
+ + + + W+ E+K +E+ E+ M++ L ++EK ++E+++K+++ +
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQ------EEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 318 TFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQ 377
++++++ +++ + R++ + W+ + K+ R R +K+ E +
Sbjct: 361 MWEQDERLREK----------EERMREQE----KMWEQEEKMQEEERIREREKKMREEEE 406
Query: 378 ALENDLREENRKQQLATEYNRKQVLRHCFTEWQH--WHGAELLKRELAL--TKEETRKKM 433
+ + ++++ E K+ + E + W ++ ++E + +E+ R +
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Query: 434 DALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSP 493
+ Q + + + E+ M K + +WE+
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE--RMWEQ----DERLREKE 520
Query: 494 PLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFH 553
R Q + ++ KT E + R + E +
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 554 NRHVFQQQLIEKQKKKLQEQQKTILELKKNL-QLAEAQWAAEHALAVTEAQSHLLSKPRE 612
+ Q++ + +Q++K+ EQ++ + E ++ + + E W E + E + + + +
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Query: 613 EEPRTCQMLVNSPVASPGTEGRSDSRNSLSG----LRRKPKQLMTPHPILKAMEERAIQR 668
+ + +M E + + G +R + +++ ++ EE+ +
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 669 AECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEK 716
E EK QEE+ Q + +E+E + R+ +EK + + EE+
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 58.2 bits (139), Expect = 4e-08
Identities = 77/348 (22%), Positives = 158/348 (45%), Gaps = 62/348 (17%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQS-HLLSKPREEEPRT 617
Q++ + +Q+K+L+EQ+K + E +K L+ + E + E + K RE+E +
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAE 677
R + R L + KQ+ ++ EER ++ E R E
Sbjct: 334 ---------------WRQEER-----LWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
Query: 678 KKKKQEEEKLAQLKAQEEER-QKREAEEKEAQLERKREEKRLKKMKE--LEKQKRIKRNQ 734
+ ++QE+ + K QEEER ++RE + +E + + +E++++K +E E++++ + Q
Sbjct: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 433
Query: 735 QLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQ---RS 791
+L ++ +E+ ++++ + W + ++ I+ EE + Q K M W Q R
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEKIW-----EQEEKIRDQEEMWG---QEKKM--WRQEKMRE 483
Query: 792 QESLARKMAQADQFYSQILLKRVIQSWLQ--YVIDLQEEVRKFCVHFLQKKIFRAWFNMV 849
QE + + + Q + + + W Q + + +E +R+ QKK+++ M
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE------QKKMWQQEEKMR 537
Query: 850 REVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQ 897
E K Q K +TW + K +EER++E ++
Sbjct: 538 EEKKTQEQEK-----------------KTWDQEEKMREEERMREREKK 568
Score = 54.3 bits (129), Expect = 5e-07
Identities = 55/261 (21%), Positives = 115/261 (44%), Gaps = 15/261 (5%)
Query: 145 EEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRL 204
+E++ QK D D + E R Q+K +++ ++ E R ++ +E ++
Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE-REKKM 401
Query: 205 RREKELEYQRIEKTLKKSAFLEAQCLVQEEKK--RKALEAKKEEEEIQREMVKLRREIIE 262
R E+E ++ EK K+ E QEEK+ ++ L +KE+ Q +M + +I E
Sbjct: 402 REEEETMREQEEKMQKQ----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457
Query: 263 RRRTVK---AAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTF 319
+ ++ W EKK + E M++ + D+E+ + +++ ++ E +
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE-QDERL 516
Query: 320 KENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQAL 379
+E ++ + W + K + W + K+ R+ R ++ E++ +
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM----REEERMREREKKMREE 572
Query: 380 ENDLREENRKQQLATEYNRKQ 400
E +RE+ K Q E R+Q
Sbjct: 573 EEMMREQEEKMQEQEEKMREQ 593
Score = 53.5 bits (127), Expect = 9e-07
Identities = 68/338 (20%), Positives = 146/338 (43%), Gaps = 43/338 (12%)
Query: 560 QQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQ 619
Q+ + +Q+++L+EQ+K I + + E W E L E + + +EE+ R +
Sbjct: 233 QEEMWRQEEELREQEKKIRKQE------EKMWRQEERLREQEGKM----REQEEKMRRQE 282
Query: 620 MLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKK 679
+ E + R LR + K+L ++ EE+ ++ E R EK
Sbjct: 283 KRLR--------EQEKELREQEKELREQ-KKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
Query: 680 KKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAI 739
+QEE Q K E+ QK +E+ + +R ++ ++M+E EK + Q E
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE-- 391
Query: 740 AKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKM 799
ER+ R+K + + + ++ +Q EE+ W Q +E +++
Sbjct: 392 -----ERIREREKKMREEEETMREQEEKMQKQEEN-----------MWEQEEKEWQQQRL 435
Query: 800 AQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGK 859
+ + ++ + +Q + + + +E++R + Q+K + W + D +
Sbjct: 436 PEQKE---KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK--KMWRQEKMREQEDQMWE 490
Query: 860 HEIAAEHSDRRILWITLRTWKKFVKFM-KEERVKEERR 896
E ++++ R W++ + KEER++E+++
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKK 528
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/258 (18%), Positives = 114/258 (44%), Gaps = 12/258 (4%)
Query: 145 EEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRL 204
+EE+ +K + + M R Q+K+ ++ + + + +++
Sbjct: 308 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER 367
Query: 205 RREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALE---AKKEEEEIQREMVKLRREII 261
REKE + EK ++ ++ + ++E +K+ E +++EE++Q++ + +
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427
Query: 262 ERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERK----RKLKEVLIQ 317
+ + + + EK ++E Q EK+ Q I EE +E+K K++E Q
Sbjct: 428 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 487
Query: 318 TFKENQQCQKRYFAAWHK----LILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLE 373
+++ ++ + + W + D R++ K + + K + R+ + Q+ E
Sbjct: 488 MWEQEEKMRDQEQKMWDQEERMWEQDERLR-EKEERMREQKKMWQQEEKMREEKKTQEQE 546
Query: 374 RETQALENDLREENRKQQ 391
++T E +REE R ++
Sbjct: 547 KKTWDQEEKMREEERMRE 564
Score = 48.5 bits (114), Expect = 3e-05
Identities = 62/272 (22%), Positives = 129/272 (47%), Gaps = 28/272 (10%)
Query: 634 RSDSRNSLSGLRRKPKQLMTPHPILKA---MEERAIQRAECRRILAEKKKKQEEEKLAQL 690
+S+ + ++ L+RK ++ P ++ EE Q E R EKK +++EEK+ +
Sbjct: 203 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE--QEKKIRKQEEKMWR- 259
Query: 691 KAQEEERQKREAEEKEAQLERKREEKRL----KKMKELEKQKR-IKRNQQLEAIAKEHYE 745
QEE +++E + +E + + +R+EKRL K+++E EK+ R K+ ++ E +E E
Sbjct: 260 --QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317
Query: 746 RVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQF 805
++ W++ +Q ++ + L+ Q K M Q+ ++ R Q ++
Sbjct: 318 KM---------WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 806 YSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAE 865
+ R + + +QEE R + +KK+ R +RE + Q + E E
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEER---IREREKKM-REEEETMREQEEKMQKQEENMWE 424
Query: 866 HSDRRILWITLRTWKKFVKFMKEERVKEERRQ 897
++ W R ++ K ++E+++E+ +
Sbjct: 425 QEEKE--WQQQRLPEQKEKLWEQEKMQEQEEK 454
Score = 45.8 bits (107), Expect = 2e-04
Identities = 58/286 (20%), Positives = 113/286 (39%), Gaps = 45/286 (15%)
Query: 69 WGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEA 128
WGQ + E++ + ++ E +E + D QE E+ + + E
Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER---------LREK 519
Query: 129 NGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDP 188
++ K + ++EE +K K M + R ++KK +++
Sbjct: 520 EERMREQK------KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 189 RLTMEMRHK-QVKENRLRREKELEYQRIEKTLKKSAFL-------------------EAQ 228
+ E K Q +E ++R ++E +++ EK ++ + E
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Query: 229 CLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKR---QEENSQNS 285
QEEK ++ E E+EE RE + RE E+ + + + ++++ QEE +
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Query: 286 SEKVMFQSTHILPDEEKMVKERKR-------KLKEVLIQTFKENQQ 324
EK+ Q + EEKM + ++ + KE I+ KE Q
Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/255 (20%), Positives = 109/255 (42%), Gaps = 37/255 (14%)
Query: 79 EQIEDHDEIYAEAQELVND----WLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKY 134
E++ + DE E +E + + W + +E +E + K + E +
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 135 DKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEM 194
K + + E+EE Q + M E + Q++K Q+ E
Sbjct: 567 KKMREEEEMMREQEEKMQEQ------------EEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
Query: 195 RHK---QVKENRLRREKELEYQRIEKTLKKSAFL---EAQCLVQEEKKRKALEA------ 242
K Q +E++++ ++E+ +++ EK ++ + E + QEEK R+ E
Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
Query: 243 --KKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDE 300
+++EE++Q + K+R + + R + W QEE EK+ Q + ++
Sbjct: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMW-----GQEEKMWGQEEKMWGQEE--MREK 727
Query: 301 EKMVKERKRKLKEVL 315
E+ ++++K K++E L
Sbjct: 728 EERIRDQKEKMQERL 742
Score = 35.8 bits (81), Expect = 0.19
Identities = 52/264 (19%), Positives = 112/264 (42%), Gaps = 44/264 (16%)
Query: 638 RNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKL----AQLKAQ 693
RN+++ K K + A E++ E + + E K+K E K Q
Sbjct: 177 RNTITNEELKKKNAELQEKLRLAESEKS----EIQLNVKELKRKLERAKFLLPQVQTNTL 232
Query: 694 EEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKG 753
+EE ++E E +E + + +++E+++ + +E +++ K +Q E + ++
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE---------- 282
Query: 754 LEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKR 813
KRLR Q K ++ E+ L Q+K R QE ++ + + + ++
Sbjct: 283 ----KRLREQEK---ELREQEKELREQKKL------REQEEQMQEQEEKMWEQEEKMREQ 329
Query: 814 VIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILW 873
+ W Q +E + + Q+K R +R+ + + E E +R +
Sbjct: 330 EEKMWRQ-----EERL------WEQEKQMREQEQKMRDQEERMWEQDERLREKEER--MR 376
Query: 874 ITLRTWKKFVKFMKEERVKEERRQ 897
+ W++ K +EER++E ++
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKK 400
Score = 32.0 bits (71), Expect = 2.8
Identities = 37/211 (17%), Positives = 88/211 (41%), Gaps = 15/211 (7%)
Query: 60 RNSDLPRSPWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEE------EG 113
+ + + W Q ++ E++ + ++ E +E++ + + +QE E E
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 114 DAKNTVSSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMED 173
+ K + + + ++ D + E+EE ++ + K M +
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKM---QEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657
Query: 174 LGRK--ENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLV 231
K E ++K Q ++ ++ + Q +E ++R ++E + EK + E +
Sbjct: 658 QEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ----EEKMWG 713
Query: 232 QEEKKRKALEAKKEEEEIQREMVKLRREIIE 262
QEEK E +++EE I+ + K++ + E
Sbjct: 714 QEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 64.7 bits (156), Expect = 4e-10
Identities = 121/616 (19%), Positives = 250/616 (40%), Gaps = 93/616 (15%)
Query: 145 EEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQ---------DKKQQKDPRLT---M 192
+EE ++TT ++ ++A +E L R+E + +++++ DP +T +
Sbjct: 76 DEEAKTTTTNTQVE-----GDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 130
Query: 193 EMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKK---RKALEAKKEEEEI 249
+ ++++ + E + ++ E ++ E + + + +K R A E KKE++E
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEK 190
Query: 250 QREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMF--QSTHILPDEEKMVKER 307
+ E E + +R ++E +E+ +++ E V+ ++ I +E K +ER
Sbjct: 191 EEE------EEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEER 244
Query: 308 KRKLKEV-----LIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRA 362
++ E+ + + KE + ++ A + RIK + ++D + +++
Sbjct: 245 EQGSDEISHHEKMEEEDKERAEAERARLEAEER----ERIKAEQDKKIADERARIEA--- 297
Query: 363 WRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKREL 422
E + A E + RE ++++ E R R E + AE +R
Sbjct: 298 ----------EEKAAAQERERREAEERERMREEEKRAAEERQRIKE-EEKRAAEERQR-- 344
Query: 423 ALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKP 482
KEE ++ + + K +A EE A V +N Q L EK
Sbjct: 345 --IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ------LEEK- 395
Query: 483 PLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQ 542
+ G ++G N + Q L + ++ + R Q
Sbjct: 396 ---KHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ 452
Query: 543 KAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAA--EHALAVT 600
+ +P F + +++ K+ K+ +E+ K+ ++ KK ++Q H L T
Sbjct: 453 EDKPT----FKKEEIKDEKI--KKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHT 506
Query: 601 EAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKA 660
E + S+P + +P G L LRR+ + + +
Sbjct: 507 E---NTFSRPGGRASVDTKEAEGAPQVEAGKR--------LEELRRRRGETES-----EE 550
Query: 661 MEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKK 720
E+ ++ E L E KKK+EE + K EEE Q+R+ EE + +L + E++RLK+
Sbjct: 551 FEKLKQKQQEAALELEELKKKREERR----KVLEEEEQRRKQEEADRKLREEEEKRRLKE 606
Query: 721 MKELEKQKRIKRNQQL 736
E + + ++ Q++
Sbjct: 607 EIERRRAEAAEKRQKM 622
Score = 60.5 bits (145), Expect = 7e-09
Identities = 112/539 (20%), Positives = 217/539 (40%), Gaps = 75/539 (13%)
Query: 234 EKKRKALEAKKEEEEIQREMVKLRR------EIIERRRTVKAAWKIEKKRQEENSQNSSE 287
E++R+ K+EE ++ E + +R E RR ++ +K++EE+ ++
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 288 KVMFQSTHILPDEEKMVKERKRKLK-----EVLIQTFKENQQCQKRYFAAWHKLILDHRI 342
+V + + +PDEE +++ L + + ++ QKR A L+ +
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEA-----LERQK 119
Query: 343 KLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVL 402
+ T++D + L R D + E+E ++ R E + + T+ +K
Sbjct: 120 EFDP--TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKN-- 175
Query: 403 RHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAM 462
W AE K+E +EE +K + S+G+ + E
Sbjct: 176 --------DWRDAEENKKEDKEKEEEEEEKP----KRGSIGENQVEVMVEEKTTESQEET 223
Query: 463 VGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKT 522
V +KNGQ ++ P E+ S +S + + L A ++ +
Sbjct: 224 VVMSLKNGQISSEEPKQEEEREQGSD-EISHHEKMEEEDKERAEAERARLEA---EERER 279
Query: 523 LGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKK 582
+ AE ++ +KA R +++ + +++K+ E+++ I E +K
Sbjct: 280 IKAEQDKKIADERARIEAEEKA---AAQERERREAEERERMREEEKRAAEERQRIKEEEK 336
Query: 583 NLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLS 642
+ E A E Q + +EEE R E R +R
Sbjct: 337 RAAEERQRIKEEEKRAAEERQ-----RIKEEEKRAA-------------EERQRAR---- 374
Query: 643 GLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEK-LAQLKAQEEERQ--- 698
+ K + K +EE+ E + I EK +++ E K + + KAQE++ Q
Sbjct: 375 -AEEEEKAKVEEQKRNKQLEEKKHAMQETK-IKGEKVEQKIEGKWVNEKKAQEDKLQTAV 432
Query: 699 -KREAEEKEAQLERKREEKRLKK---MKELEKQKRIKRNQQLEAIAKEHYERVLLRKKG 753
K++ EEK +++ KRE+ + K KE K ++IK++++ KE + + RKKG
Sbjct: 433 LKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE----PKEEVKSFMDRKKG 487
Score = 52.4 bits (124), Expect = 2e-06
Identities = 72/294 (24%), Positives = 131/294 (44%), Gaps = 39/294 (13%)
Query: 506 SLQNVSLSAPGNK-QHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIE 564
++ + SLS P + Q+ T E +++ +E+ + + E + + ++ ++ E
Sbjct: 124 TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDA--E 181
Query: 565 KQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNS 624
+ KK+ +E+++ E K + E Q TE+Q E L N
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQ----------EETVVMSLKNG 231
Query: 625 PVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECR-RILAEKKKKQE 683
++S + + + K M +A ERA AE R RI AE+ KK
Sbjct: 232 QISSEEPKQEEEREQGSDEISHHEK--MEEEDKERAEAERARLEAEERERIKAEQDKKIA 289
Query: 684 EEKL---AQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIK--------- 731
+E+ A+ KA +ER++REAEE+E R REE++ + E+++RIK
Sbjct: 290 DERARIEAEEKAAAQERERREAEERE----RMREEEK----RAAEERQRIKEEEKRAAEE 341
Query: 732 --RNQQLEAIAKEHYERVL-LRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRK 782
R ++ E A E +R+ K+ E +R R + ++ +V E+ + L+ K
Sbjct: 342 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Score = 46.6 bits (109), Expect = 1e-04
Identities = 73/345 (21%), Positives = 155/345 (44%), Gaps = 23/345 (6%)
Query: 559 QQQLIEKQKKKLQEQQKTILE----LKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEE 614
+ + EK++K Q++ +E + K+ Q + + A E+ E + EE+
Sbjct: 143 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEE-----EEEK 197
Query: 615 PRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRI 674
P+ + N V E ++S+ + K Q+ + P + E+
Sbjct: 198 PKRGSIGENQ-VEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEK 256
Query: 675 LAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKR---EEKRLKKMKELEKQKRIK 731
+ E+ K++ E + A+L+A+E ER K E ++K A ER R EEK + +E + + +
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIAD-ERARIEAEEKAAAQERERREAEERE 315
Query: 732 RNQQLEAIAKEHYERVL-LRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQR 790
R ++ E A E +R+ K+ E +R++ + K + AEE + + K QR
Sbjct: 316 RMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEK---RAAEERQRIKEEEKRAAEERQR 372
Query: 791 SQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVR 850
++ K A+ ++ L+ + + I ++ +K ++ +K +A + ++
Sbjct: 373 ARAEEEEK-AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEK--KAQEDKLQ 429
Query: 851 EVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEER 895
+ QG+ + + R L T+KK + +K+E++K+++
Sbjct: 430 TAVLKKQGEEKGTKVQAKREKLQEDKPTFKK--EEIKDEKIKKDK 472
Score = 43.5 bits (101), Expect = 0.001
Identities = 122/645 (18%), Positives = 248/645 (38%), Gaps = 90/645 (13%)
Query: 176 RKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLK-----KSAFLEAQCL 230
R+ Q++ +QK ++ QV+ N + E + + ++AFLE
Sbjct: 43 RRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLAR 102
Query: 231 VQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVM 290
+E ++++ EA + ++E + + RR A + E +EE S++ E+
Sbjct: 103 REERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTA-ENETTEKEEKSESRQERYE 161
Query: 291 FQSTHILP-----DEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLG 345
+ T + ++ + +E K++ KE KE ++ +K
Sbjct: 162 IEETETVTKSYQKNDWRDAEENKKEDKE------KEEEEEEKP----------------- 198
Query: 346 KAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALEN-DLREENRKQQLATEYNRKQVLRH 404
K G++ + ++++ V + T + E +L+N + E KQ+ E ++ H
Sbjct: 199 KRGSIGENQVEVMV----EEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH 254
Query: 405 CFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVG 464
E + AE + L + E K A K A+ + I E+A A
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIK--------AEQDKKIADERARIEAEEKAAA--- 303
Query: 465 PPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLG 524
QE E+ + + R + + + + K+ +
Sbjct: 304 ------QERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI-----KEEEKRA 352
Query: 525 AEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNL 584
AE Q+ E + +++ + V +Q+ ++ ++K Q+T ++ +K
Sbjct: 353 AEERQRIKEEE--KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410
Query: 585 QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGL 644
Q E +W E + Q+ +L K EE+ Q T + + ++
Sbjct: 411 QKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 470
Query: 645 RRKPKQLMTPH-PILKAMEERAIQRAECRRILAEKKKKQEEE-----KLAQLKAQEEERQ 698
++PK+ + K E Q E + K K E A + +E E
Sbjct: 471 DKEPKEEVKSFMDRKKGFTEVKSQNGE---FMTHKLKHTENTFSRPGGRASVDTKEAEGA 527
Query: 699 KR-EAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPW 757
+ EA ++ +L R+R E ++ ++L KQK+ + +LE + K+ E R+K LE
Sbjct: 528 PQVEAGKRLEELRRRRGETESEEFEKL-KQKQQEAALELEELKKKREE----RRKVLEEE 582
Query: 758 KRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQA 802
++ R Q + + ++ EE +R +E + R+ A+A
Sbjct: 583 EQRRKQEEADRKLREEEEK------------RRLKEEIERRRAEA 615
Score = 33.1 bits (74), Expect = 1.2
Identities = 26/121 (21%), Positives = 60/121 (49%), Gaps = 4/121 (3%)
Query: 685 EKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHY 744
E+ +L+ Q+ E + EAE Q EE+ ++ + +Q+R+++ Q+ E++ +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG-QVT 63
Query: 745 ERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQ 804
++V + + P + + + N QV + + FL+R + +R Q+ L + + +
Sbjct: 64 DQVEVNAQNSVPDEEAK-TTTTNTQVEGDDEAAFLER--LARREERRQKRLQEALERQKE 120
Query: 805 F 805
F
Sbjct: 121 F 121
Score = 32.3 bits (72), Expect = 2.1
Identities = 47/253 (18%), Positives = 110/253 (43%), Gaps = 26/253 (10%)
Query: 71 QITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANG 130
++ + K ++Q+E+ E + + + ++ K++ + +E++ ++V + G
Sbjct: 382 KVEEQKRNKQLEEKKHAMQETK-IKGEKVEQKIEGKWVNEKKAQEDKLQTAVL---KKQG 437
Query: 131 HLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMED-LGRKEN-QDKKQQKDP 188
K K L+E++ + ++ D + K+ ++ + RK+ + K Q
Sbjct: 438 EEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 497
Query: 189 RLTMEMRHKQVKENRLRRE--------KELEY-------QRIEKTLKKSAFLEAQCLVQE 233
+T +++H EN R KE E +R+E+ ++ E++ E
Sbjct: 498 FMTHKLKHT---ENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF--E 552
Query: 234 EKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQS 293
+ K+K EA E EE++++ + R+ + E + K K R+EE + E++ +
Sbjct: 553 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 612
Query: 294 THILPDEEKMVKE 306
+KM ++
Sbjct: 613 AEAAEKRQKMPED 625
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 64.7 bits (156), Expect = 4e-10
Identities = 210/1013 (20%), Positives = 383/1013 (37%), Gaps = 195/1013 (19%)
Query: 70 GQITDLKTSEQIEDHDEIYA-----------EAQELVNDWLDTKLKQELASEE----EGD 114
G++ +L SE++ED +E+ A E EL D D KL A +E E
Sbjct: 966 GKVKEL--SERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENK 1023
Query: 115 AKNTVSSVTIMPEANGHLKYDK------FDDLCGYLEEEEESTTVQKFIDHLLHKNVVDS 168
KN + + E+ L +K G L+ EE+ + L + V D
Sbjct: 1024 VKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDL 1083
Query: 169 AMMEDLGRKENQDKKQQK-----DPRLTMEM-----RHKQVKENRLRR------------ 206
+ +K D ++ K D +LT E + KQ E +L++
Sbjct: 1084 ECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRV 1143
Query: 207 -EKELEYQRIEKTLKK--------SAFLEAQCLVQEEKKRKALEAKKEEEEI-------- 249
+++L +++K +K+ LEA+ + +++ EA +E EE+
Sbjct: 1144 EDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAG 1203
Query: 250 -------------QREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHI 296
+ E+ +LRRE+ E +A +++Q E + E+V
Sbjct: 1204 GASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQV------- 1256
Query: 297 LPDEEKMVKERKRKLKEVL---IQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDW 353
D + V+++ K K L + N + R A+ KL + +L +A +
Sbjct: 1257 --DSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEA-KIKVE 1313
Query: 354 KIQLKVLRAWRDYTRFQ-------KLERETQALENDLRE---------ENRKQQLATEYN 397
++Q ++ A R Q +L E + L + L E ++QL E
Sbjct: 1314 ELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESK 1373
Query: 398 RKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASL------GKLSANGLS 451
K L H + H +LL RE + E + ++ LL A+ K A+ +
Sbjct: 1374 AKSALAHAVQALR--HDCDLL-REQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQ 1430
Query: 452 GISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVS 511
EEA + ++ +E + L + L T + + +
Sbjct: 1431 RTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAA 1490
Query: 512 LSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQL-----IEKQ 566
L + L Q+ L +++ L F RH ++ L ++++
Sbjct: 1491 LDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRE 1550
Query: 567 KKKLQEQ-----------QKTILELKKNLQLAEAQWA--------AEHALAVTEAQSHLL 607
K LQE+ K+I EL+K + E + + AE AL + E ++ +
Sbjct: 1551 NKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRI 1610
Query: 608 S--------------KPREEE----PRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPK 649
++EE R Q V S AS E R +RN L++K +
Sbjct: 1611 QLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETR--ARNEALRLKKKME 1668
Query: 650 ------QLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKL-AQLKAQEEERQKR-- 700
+L H +A E +A R ++ E+ + EE++L A+L Q + ++R
Sbjct: 1669 GDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRAS 1728
Query: 701 ----EAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEP 756
E EE A LE+ +RL + + LE +R+ + +L +KK LE
Sbjct: 1729 LLAAELEELRAALEQGERSRRLAEQELLEATERLN-------LLHSQNTGLLNQKKKLE- 1780
Query: 757 WKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQ 816
L S + + A+E + K +T E L ++ + L+R+ +
Sbjct: 1781 -ADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAH------LERMKK 1833
Query: 817 SWLQYVIDLQ---EEVRKFCVHFLQKKIFRAWFNMVR-EVKIDSQGKHEIAAEHSDRRIL 872
+ Q V +LQ EE + + +K++ + + E ++D++ K A R+
Sbjct: 1834 TLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRK-- 1891
Query: 873 WITLRTWKKFVKFMKEERVKEERRQQLRRKVVEILPDFQVPGRYHELYQQSDT 925
R K+ +E+R R Q L K+ + ++ ++ E QQ++T
Sbjct: 1892 --HERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYK--RQFEEAEQQANT 1940
Score = 51.2 bits (121), Expect = 4e-06
Identities = 136/667 (20%), Positives = 248/667 (37%), Gaps = 96/667 (14%)
Query: 189 RLTMEMRHKQV--KENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEE 246
R +E H + ++N L + + E + ++ L + E K ++ E ++E
Sbjct: 919 RQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDE 978
Query: 247 EEIQREMVKLRREIIERRRTVK-----AAWKIEKKRQEENSQNSSEKVMFQSTHILPDEE 301
EE+ ++ RR++ + +K + K +E+ + + K + + L +
Sbjct: 979 EEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESV 1038
Query: 302 KMVKERKRKLKEVLIQTFKENQQCQKRYFAAWH-KLILDHRIKLGKAGTLSDWKIQLKVL 360
+ + K+ L+E Q + Q + R A KL L+ +++ + + K+++
Sbjct: 1039 ARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTE 1098
Query: 361 RAWRDYTRFQKLERET--------QALENDLREENRK-QQLATEYNRKQVLRHCFTEWQH 411
RA R KL +E+ Q LE L++++ + QL+ +Q+L
Sbjct: 1099 RAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLL--------- 1149
Query: 412 WHGAELLK--RELALTKEETRKKMDALLQA-ASLGKLSANGLSGIS-----LPEEATAMV 463
GA++ K +EL EE ++++A A A + K A + L E A
Sbjct: 1150 --GAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASA 1207
Query: 464 GP----PVKNGQETAVPPLWEKPPLGSSGCMLS----PPLGRTTTGNLQGSLQNVSLSAP 515
G + + + E+ L + + G G SLQ V
Sbjct: 1208 GQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKL- 1266
Query: 516 GNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNR-------HVFQQQLIEKQKK 568
K+ L E + ETL AE LC + Q+QL + +
Sbjct: 1267 -EKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQ 1325
Query: 569 K-------------LQEQQKTILELKKNLQLA---------------EAQWAAEHALAVT 600
+ L+E++ I +L + LA +A+ A HA+
Sbjct: 1326 RGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQAL 1385
Query: 601 EAQSHLLSKPREEEPRTCQML------VNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTP 654
LL + EEE L N+ VA ++ +D+ L K+L
Sbjct: 1386 RHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLAL- 1444
Query: 655 HPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKRE 714
+ +A E A+C + K + Q E + L+ + ++K+ LER E
Sbjct: 1445 -RLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALE 1503
Query: 715 EKRLKK---MKELEKQKRIKRNQQLEAIAKEH-YERVLLRKKGLEPWKRLRMQSKQNIQV 770
E+R ++ +ELE +R R E H +E L + LE KR ++ I
Sbjct: 1504 ERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEAL---EALETLKRENKNLQEEISD 1560
Query: 771 AEEHYSL 777
+ SL
Sbjct: 1561 LTDQVSL 1567
Score = 37.0 bits (84), Expect = 0.086
Identities = 37/193 (19%), Positives = 90/193 (46%), Gaps = 23/193 (11%)
Query: 139 DLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQ 198
DL E EE+ ++ + K + D+AMM + +KE + + T+E ++
Sbjct: 1782 DLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRE 1841
Query: 199 VK------ENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEE----- 247
++ E R + + Q++E +++ LEA+ +++K +AL+ ++ E
Sbjct: 1842 LQARLEEAEQAALRGGKKQVQKLEAKVRE---LEAELDAEQKKHAEALKGVRKHERRVKE 1898
Query: 248 -----EIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEK 302
E R+ + ++++++ ++ ++K + + E+ + + K ++ H L D E+
Sbjct: 1899 LAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYR-KAQHELDDAEE 1957
Query: 303 ---MVKERKRKLK 312
M + + KL+
Sbjct: 1958 RADMAETQANKLR 1970
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 64.3 bits (155), Expect = 5e-10
Identities = 170/800 (21%), Positives = 310/800 (38%), Gaps = 123/800 (15%)
Query: 131 HLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKN----VVDSAMMEDLGRKENQDKKQQK 186
H ++ F ++C L++E + D + + + + A+ ED+ + Q+ + K
Sbjct: 1281 HPSWELFQEICPLLKKESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHK 1340
Query: 187 DPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEA-------QCLVQEEKKRKA 239
+ E + ++ + L E E Q I K KK FLE + +EEKK
Sbjct: 1341 EVMPREEEQAQKKARDMLGLE---ETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQ 1397
Query: 240 LEAKKEEEEIQRE--MVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHIL 297
K+ + +Q+E + K++RE+ + R + + +E+ + + VM + T
Sbjct: 1398 KSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSW 1457
Query: 298 PDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAG--------- 348
D +K E K Q E ++ K + W K +L KL +AG
Sbjct: 1458 QDWKKAWDEWK--------QVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEM 1509
Query: 349 -------TLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQV 401
+WK + + + + + K E E E RE K+Q TE R
Sbjct: 1510 LQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQ 1569
Query: 402 LRHCFTEWQHWH-------------------GAELLKRELALTKEETRKKMDALLQAASL 442
H +W H E L +E +E RK A ++
Sbjct: 1570 EEH---KWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQD 1626
Query: 443 GKLSANGLSGISLPEEATAMVGPPVKNGQE------TAVPPLWEK-----PPLGSSGCML 491
+ A + EE A G + E + WEK L G L
Sbjct: 1627 DREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKL 1686
Query: 492 S--PPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCL 549
+ + L QN+ + Q K L E + E L S K E L
Sbjct: 1687 AEVKNILAQKVEELPQREQNL------DWQEKELAQELEELEWDMEEL---SWKEEEL-- 1735
Query: 550 GHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQ---SHL 606
+ + +L+E +KKKL E+++ + ++ L E + A E L + E + H
Sbjct: 1736 ------NQEEGKLVE-EKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK 1788
Query: 607 LSKPREEE--PRTCQMLVNSPVASPGTEGRSDSRNSLSGLRR------KPKQLMTPHPIL 658
P EEE R + L+ + + R NS+ L + + K L L
Sbjct: 1789 EKMPEEEERLGRKREQLIEKKMKL--AQKRERWINSMEELTKNKMILYQKKNLAQEKKNL 1846
Query: 659 KAMEERAIQRAEC------RRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERK 712
+E+ QR E R ++K+ Q + KL + +++ +EKE +++K
Sbjct: 1847 AQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKK 1906
Query: 713 RE----EKRLKKMKE--LEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQ 766
+ EK+L ++++ +KQ+++ + + A+ K + + L+ K + + +
Sbjct: 1907 EKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLE 1966
Query: 767 NIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQ--FYSQILLKRVIQSWLQYVID 824
++AEE L ++ K L+ + + S RKM Q +Q F ++ L+ I ++
Sbjct: 1967 MKRLAEEKMRL-VEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILA 2025
Query: 825 LQE-EVRKFCVHFLQ-KKIF 842
++E E+ K + F + ++IF
Sbjct: 2026 MEESEIAKGKLEFTRGQRIF 2045
Score = 62.4 bits (150), Expect = 2e-09
Identities = 119/615 (19%), Positives = 249/615 (40%), Gaps = 62/615 (10%)
Query: 171 MEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCL 230
ME+L KE ++ Q++ +L E K+ E+ L +QR + + +++ + + L
Sbjct: 1725 MEELSWKE--EELNQEEGKLVEE------KKKLAEEEEALAWQREKLSEEETKLAQEEEL 1776
Query: 231 VQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVM 290
+ +EK++ A +K EE +R + + R ++IE++ +K A K E+ ++ ++
Sbjct: 1777 LIQEKEKLAQHKEKMPEEEER-LGRKREQLIEKK--MKLAQKRERWINSMEELTKNKMIL 1833
Query: 291 FQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTL 350
+Q ++ +++ + +E KE L Q KEN K K ++ + KLG +
Sbjct: 1834 YQKKNLAQEKKNLAQE-----KEKLAQR-KENLLYNKERLTHSKKQLVQVKNKLGMFNKI 1887
Query: 351 S---DWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFT 407
+ K+ + + + + E++ +E+ L +KQ+ + K L
Sbjct: 1888 LAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLA---KKQEKLAQEKMKLALEKAMV 1944
Query: 408 EWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKL--SANGLSGISLPEEATAMVGP 465
+ G + L+ EL + KEE ++ A +L LS PE +
Sbjct: 1945 Q-----GKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMT 1999
Query: 466 PVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNL----------QGSLQNVSLSAP 515
V+ L EK L +L+ G L QG + S
Sbjct: 2000 QVEQELFERKLSLEEKILLHEDR-ILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRK 2058
Query: 516 GNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQK 575
K+ ++L EP++ + L+ ++ L + + +++++ +++ +
Sbjct: 2059 LIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKL 2118
Query: 576 TILEL----KKNLQLAEAQWAAEHALAVTEAQSHLLSKPRE--EEPRTCQMLVNSPVASP 629
I E K++ + + A + +++K + EE + +
Sbjct: 2119 DIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDD 2178
Query: 630 GTEGRSDSRNSLSGLRR------------KPKQLMTPHPILKAMEERAIQRAECRRILAE 677
EG + + L+R KPK+ + EE + E L +
Sbjct: 2179 EEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMES---LLD 2235
Query: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLE 737
+ +KQE + + +EEE ++ E E +E + ERK EE+ +K E E++++ K+ ++ +
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 738 AIAKEHYERVLLRKK 752
+ E V K+
Sbjct: 2296 KEEVQEKEEVFEEKE 2310
Score = 53.5 bits (127), Expect = 9e-07
Identities = 154/801 (19%), Positives = 315/801 (39%), Gaps = 155/801 (19%)
Query: 177 KENQDKKQ-QKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEK 235
KE +K+ Q++ +L +E L+ +K+L+++ ++ + +++ E+
Sbjct: 1482 KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSK-----EQ 1536
Query: 236 KRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWK---IEKKR-QEENSQNSSEKVMF 291
+ K E EEE+ RE + +++ E +R ++ K I +KR + E + E+ +
Sbjct: 1537 QYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLA 1596
Query: 292 QSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRY--FAAWHKLILDHRIKLGKAGT 349
Q L EE+ + + +RKL + ++ +++++ + FA + + KL +
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656
Query: 350 LSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEW 409
K + K+ + W +K+ RE + L + + + + + R +W
Sbjct: 1657 KLAQK-RKKLAKKW------EKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709
Query: 410 QHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKN 469
Q A+ L+ EL EE K + L Q GKL L EE A+
Sbjct: 1710 QEKELAQELE-ELEWDMEELSWKEEELNQEE--GKLVEEKKK---LAEEEEALA------ 1757
Query: 470 GQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQ 529
W++ L L+ Q L ++ + L +
Sbjct: 1758 ---------WQREKLSEEETKLA---------------QEEELLI---QEKEKLAQHKEK 1790
Query: 530 QPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEA 589
P E L ++QLIEK+ K Q++++ I ++ +L +
Sbjct: 1791 MPEEEERLGRK------------------REQLIEKKMKLAQKRERWINSME---ELTKN 1829
Query: 590 QWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPK 649
+ + + + +L + + R +L N E + S+ L ++ K
Sbjct: 1830 KMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNK-------ERLTHSKKQLVQVKNK-- 1880
Query: 650 QLMTPHPILKAMEERAIQRAECRRILAEKKKKQE-EEKLAQLKAQEEERQKREAEEK--- 705
L + IL +EE+ Q E ++ +K+K E E+KL Q++ ++Q++ A+EK
Sbjct: 1881 -LGMFNKILAQVEEKLTQEKET--VIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKL 1937
Query: 706 -------------EAQLERKREEKRLK-KMKELEKQK----------------RIKRNQQ 735
+L+ +EEK L +MK L ++K R ++
Sbjct: 1938 ALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRK 1997
Query: 736 LEAIAKEHYERVL-LRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQES 794
+ + +E +ER L L +K L R+ + I + F + + + QR
Sbjct: 1998 MTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLE---FTRGQRIFVQGQRKLAK 2054
Query: 795 LARKMAQADQFYSQ--ILLKRVIQSWLQYVID----LQEEVRKFCVHFLQKKIFRAWFNM 848
+RK+ + + S+ L +++++ + D QEE++ K+ RA F
Sbjct: 2055 ASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIK-------MTKMKRALFVK 2107
Query: 849 VREVKID-----------SQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQ 897
R + I+ S+ + E+ + ++++ + K + + +E E
Sbjct: 2108 ERRLSIEQSKLDIKEWDFSEKRSELTKD--EKKLARKQRKLANKMRRMINKEEKMTEEES 2165
Query: 898 QLRRKVVEILPDFQVPGRYHE 918
+L RK E++ D + G E
Sbjct: 2166 KLARKHSEVILDDEEEGGIEE 2186
Score = 50.4 bits (119), Expect = 8e-06
Identities = 148/728 (20%), Positives = 285/728 (39%), Gaps = 123/728 (16%)
Query: 71 QITDLKTSEQIED--HDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEA 128
++ +L EQ D E+ E +EL D + K+E ++EEG + EA
Sbjct: 1696 KVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEA 1755
Query: 129 NGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDP 188
+ +K + L +EEE +K + L E LGRK Q
Sbjct: 1756 LAWQR-EKLSEEETKLAQEEELLIQEK--EKLAQHKEKMPEEEERLGRKREQ-------- 1804
Query: 189 RLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEE 248
+ +M+ Q +E + +EL ++ KK+ E + L QE++K L +KE
Sbjct: 1805 LIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEK---LAQRKENLL 1861
Query: 249 IQRE-MVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKER 307
+E + +++++ Q +N K++ Q L E++ V ++
Sbjct: 1862 YNKERLTHSKKQLV----------------QVKNKLGMFNKILAQVEEKLTQEKETVIKK 1905
Query: 308 KRKLKEV---LIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWR 364
K KL E L+Q + Q++ KL L+ + GK K LR
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGK-----------KRLRGEL 1954
Query: 365 DYTRFQK-LERETQAL-ENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKREL 422
D + +K L E + L E +R K+ L+ + + T+ + EL +R+L
Sbjct: 1955 DIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQ----ELFERKL 2010
Query: 423 ALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKP 482
+L +E+ D +L ++ E A GQ V
Sbjct: 2011 SL-EEKILLHEDRIL----------------AMEESEIAKGKLEFTRGQRIFV------- 2046
Query: 483 PLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQ 542
QG + S K+ ++L EP++ N+ L+ +
Sbjct: 2047 ---------------------QGQRKLAKASRKLIKKRESLSKEPAK---LNKILKALQK 2082
Query: 543 KAEPLCLGHFHNRHVFQQQL-IEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTE 601
R + Q+++ + K K+ L +++ + + L + E + +E +T+
Sbjct: 2083 LTR-------DERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDF-SEKRSELTK 2134
Query: 602 AQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAM 661
+ L K R+ + +M +N E + ++S L + + + ++ +
Sbjct: 2135 DEKKLARKQRKLANKMRRM-INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193
Query: 662 EERAIQRAECRRILAEKKK--------KQEEEKLAQLKAQEEERQKREA----EEKEAQL 709
+ R +R E +R K+K + EE ++++ +E +K+E+ EE+E +
Sbjct: 2194 KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREE 2253
Query: 710 ERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQ 769
E +REE+ +++ +E K++ +Q+E +E ++ +KK K + K+ I
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 770 VAEEHYSL 777
EE SL
Sbjct: 2314 SEEETESL 2321
Score = 46.2 bits (108), Expect = 1e-04
Identities = 52/240 (21%), Positives = 111/240 (46%), Gaps = 15/240 (6%)
Query: 76 KTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYD 135
K SE +D ++ + ++L N K+E +EEE S V + E G ++ +
Sbjct: 2128 KRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEE 2187
Query: 136 KFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMR 195
++ +L+ K D K S+ ++++ +E+ ++ + L E+
Sbjct: 2188 ---EVIPFLKRRWRKRKEAKRGDKPKEKF---SSQVDEVESEEHFSEEMES---LLDELE 2238
Query: 196 HKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVK 255
++ + E+E E +R E+ +++ E + +EE + K +E K+EEE+ +++ K
Sbjct: 2239 KQESLSSEEEEEREEEEEREEEEVREE---EEERKEEEEGEEKQVE-KEEEEKKKKKKEK 2294
Query: 256 LRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMV--KERKRKLKE 313
+ E+ E+ + +I + + E+ + E+ S D EK + KE++ KL+E
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQE 2354
Score = 37.7 bits (86), Expect = 0.050
Identities = 26/103 (25%), Positives = 57/103 (55%), Gaps = 15/103 (14%)
Query: 662 EERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREA----EEKEAQLERKREEKR 717
EE+ +++ E EKKKK++E+K +++ +EE +++E EE E+ + + EE+
Sbjct: 2276 EEKQVEKEE-----EEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEES 2330
Query: 718 LKKMKELEKQKRIKRNQQLEAIAKEHY------ERVLLRKKGL 754
+E++++K I + ++ + ++ ERVL +G+
Sbjct: 2331 CSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGV 2373
Score = 36.2 bits (82), Expect = 0.15
Identities = 37/179 (20%), Positives = 86/179 (48%), Gaps = 15/179 (8%)
Query: 147 EEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRR 206
EEES +K H V+ ++D +E ++++ P L R K+ + R +
Sbjct: 2162 EEESKLARK------HSEVI----LDD--EEEGGIEEEEVIPFLKRRWR-KRKEAKRGDK 2208
Query: 207 EKELEYQRIEKTLKKSAFLEA-QCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRR 265
KE ++++ + F E + L+ E +K+++L ++ EEEE + E + E+ E
Sbjct: 2209 PKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSE-EEEEREEEEEREEEEVREEEE 2267
Query: 266 TVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQ 324
K + E+K+ E+ + +K + + ++E++ +E++ + E ++ + ++
Sbjct: 2268 ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Score = 35.0 bits (79), Expect = 0.33
Identities = 43/209 (20%), Positives = 86/209 (41%), Gaps = 22/209 (10%)
Query: 76 KTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYD 135
K SE I D +E +E V +L + ++ ++ K SS E+ H +
Sbjct: 2170 KHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFS-E 2228
Query: 136 KFDDLCGYLE-------------EEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDK 182
+ + L LE EEEE ++ + + + + + ++E + K
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK 2288
Query: 183 KQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEA 242
K++K+ + Q KE ++E+ + ++L E C ++EE R+
Sbjct: 2289 KKKKEKK----KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL 2344
Query: 243 KKEE----EEIQREMVKLRREIIERRRTV 267
KKE+ +E +R+ ++ R ++ R V
Sbjct: 2345 KKEKQFKLQEQRRKSLRGRERVLSILRGV 2373
Score = 34.3 bits (77), Expect = 0.56
Identities = 109/515 (21%), Positives = 205/515 (39%), Gaps = 61/515 (11%)
Query: 416 ELLKRELALTKEETRKKMDALLQAASLGKLSAN----GLSGISLPEEATAMVGPPVKNGQ 471
++ K +ALT + +K D + A+ KL G + EE T PPV
Sbjct: 1159 DISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINEETT----PPVMEQP 1214
Query: 472 ETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQP 531
T + + G SG + G + +L L + +S K + L AE
Sbjct: 1215 VTKKVKIQGRGASGISGRRSTAGDGSSWRDDLC-RLMALRISGSQTKMSENLNAE----- 1268
Query: 532 GSNETLRTTSQKAEPLCLGHFHNRHVFQQ--QLIEKQKKKLQEQQK--TILELKKNLQLA 587
L T +Q+ + + + +FQ+ L++K+ K L E + KK + +
Sbjct: 1269 -----LVTFAQE---MLVDRHPSWELFQEICPLLKKESKVLLEDLDWDVVPPEKKPIFIQ 1320
Query: 588 EAQWAAEHALAVT-EAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRR 646
E + VT E H PREEE Q + T+ + L
Sbjct: 1321 EGAIREDMIQGVTQEVIRHKEVMPREEEQ--AQKKARDMLGLEETQVILKKGKKVIFL-- 1376
Query: 647 KPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQ--EEERQKREAEE 704
+P + I K E++ Q++ + +K Q+E K+ ++K + +EER E E
Sbjct: 1377 EPGNVTMGKEISKKEEKKTFQKSPKQG----RKAVQKERKVGKIKREMTKEERDMSEEVE 1432
Query: 705 KEAQLERK--REEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRM 762
+ A LE K ++E +L ++ + K+ + + H E K E W++ +
Sbjct: 1433 EMATLEEKVVKQEGKLVMIERTPSWQDWKK--AWDEWKQVHGETRKSWKAWKEEWEKRLL 1490
Query: 763 QSKQNIQVAEEHYS---LFLQRKYMLTWFQRSQ--ESLARKMAQADQF--YSQILLKRVI 815
Q ++ + A E S LQ L W + Q E++ ++ Q+ ++ L+ +
Sbjct: 1491 QEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEV 1550
Query: 816 --------QSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHS 867
Q + +QEE + +H +K RA +E + +Q + ++A E
Sbjct: 1551 SREGEEKEQQVTEEQRHIQEEHKWARIH---RKRARAEKKRAQEERKLAQEEEKLAQE-- 1605
Query: 868 DRRILWITLRTWKKFVKFMKEERVKEERRQQLRRK 902
+R++ + + +VK +++R + + +K
Sbjct: 1606 ERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQK 1640
Score = 34.3 bits (77), Expect = 0.56
Identities = 59/265 (22%), Positives = 114/265 (43%), Gaps = 50/265 (18%)
Query: 205 RREKELEYQRIEKT-LKKSAFLEAQCLVQEEKK---------RKALEAKKEEEEI---QR 251
R E++L + I+ T +K++ F++ + L E+ K K E K+E+++ QR
Sbjct: 2085 RDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQR 2144
Query: 252 EMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEK--------- 302
++ R +I + E+K EE S+ + + S IL DEE+
Sbjct: 2145 KLANKMRRMINK----------EEKMTEEESKLARK----HSEVILDDEEEGGIEEEEVI 2190
Query: 303 -MVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLR 361
+K R RK KE K + ++++ + ++ + L + + Q + L
Sbjct: 2191 PFLKRRWRKRKEA-----KRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQ-ESLS 2244
Query: 362 AWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRE 421
+ + R ++ ERE E ++REE +++ E KQV + E + + K+E
Sbjct: 2245 SEEEEEREEEEERE----EEEVREEEEERKEEEEGEEKQVEKE---EEEKKKKKKEKKKE 2297
Query: 422 LALTKEETRKKMDALLQAASLGKLS 446
KEE ++ + ++ LS
Sbjct: 2298 EVQEKEEVFEEKEEIMSEEETESLS 2322
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 63.9 bits (154), Expect = 7e-10
Identities = 152/725 (20%), Positives = 295/725 (40%), Gaps = 102/725 (14%)
Query: 69 WGQITDLKTSEQIE-DHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPE 127
W T +K Q+ +E+ A+ +ELV +++LA+E T+ S + +
Sbjct: 828 WRLFTKVKPLLQVSRQEEEMMAKEEELVK-----VREKQLAAENRLTEMETLQSQLMAEK 882
Query: 128 ANGHLKYDKFDDLCGYLEEEEESTTVQKF-IDHLLHKNVVDSAMMEDLGRKENQDKKQQK 186
+ +LC EE T +K ++ + H +++ + E+ R ++ +++K
Sbjct: 883 LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHD--LEARVEEEEERCQHLQAEKKK 940
Query: 187 DPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKK-- 244
+ E+ + +E R++ +LE E LKK LE + ++ E++ K + KK
Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK---LEEEQIILEDQNCKLAKEKKLL 997
Query: 245 ------------EEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQ 292
EEEE + + KL+ + ++ E+ R+EE + EK +
Sbjct: 998 EDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLE-----ERLRREEKQRQELEKTRRK 1052
Query: 293 STHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYF-----AAWHKLILDHRIKLGKA 347
D + E + ++ E+ +Q K+ ++ Q AA + L +L
Sbjct: 1053 LEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIREL--E 1110
Query: 348 GTLSDWKIQLKVLRAWRDYTRFQK--LERETQALENDLRE--ENRKQQLATEYNRKQ--- 400
+S+ + L+ RA R+ QK L E +AL+ +L + ++ Q R+Q
Sbjct: 1111 SQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170
Query: 401 VLRHCFTEWQHWHGAELLK---------RELALTKEETRKKMDALLQAASLGKLSANGLS 451
+L+ E H A++ + ELA E+T K++ A L+ A K +
Sbjct: 1171 ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT-KRVKANLEKA---KQTLENER 1226
Query: 452 GISLPEEATAMVGPPVKNGQETAVPP-LWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNV 510
G E + G + V L E + G + L T LQ L NV
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT-KLQVELDNV 1285
Query: 511 S-----LSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEK 565
+ + +K K A SQ + E L+ +++ L + + +E
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLST---------KLKQVED 1336
Query: 566 QKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSP 625
+K +EQ + E K NL E +A AQ + K E+ +
Sbjct: 1337 EKNSFREQLEEEEEAKHNL---------EKQIATLHAQVADMKKKMEDSVGCLET----- 1382
Query: 626 VASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKK---- 681
E + + L GL ++ ++ + + L+ + R Q + + + +++
Sbjct: 1383 ----AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACN 1438
Query: 682 --QEEEKLAQLKAQEEERQKREAEEKE-AQLE-RKREEKRLKKMKELEKQKRIKRNQQLE 737
++++K QL A+E+ + AEE++ A+ E R++E K L + LE + +++ +LE
Sbjct: 1439 LEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALE--EAMEQKAELE 1496
Query: 738 AIAKE 742
+ K+
Sbjct: 1497 RLNKQ 1501
Score = 50.8 bits (120), Expect = 6e-06
Identities = 99/406 (24%), Positives = 181/406 (44%), Gaps = 54/406 (13%)
Query: 559 QQQLIEKQKKKLQ-----------EQQKTILELKKNLQLAEAQWAAEHALAVTE---AQS 604
Q+Q +EK ++KL+ E Q I ELK +QLA+ + + ALA E AQ
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK--MQLAKKEEELQAALARVEEEAAQK 1099
Query: 605 HL-LSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEE 663
++ L K RE E + ++ E R S + ++ + L LK E
Sbjct: 1100 NMALKKIRELESQISEL----------QEDLESERASRNKAEKQKRDLGEELEALKTELE 1149
Query: 664 RAIQRAECRRILAEKK-------KKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEK 716
+ ++ L K+ KK EE+ +AQ +E +++ ++ E E+ + K
Sbjct: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK 1209
Query: 717 RLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSK-QNIQVA-EEH 774
R+K LEK K+ N++ E +A E +VLL+ KG KR +++++ Q +QV E
Sbjct: 1210 RVK--ANLEKAKQTLENERGE-LANE--VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEG 1264
Query: 775 YSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLK-RVIQSWLQYVID-LQEEVR-K 831
+ + +T Q +++ ++Q+D S++ ++S LQ + LQEE R K
Sbjct: 1265 ERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQK 1324
Query: 832 FCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERV 891
+ K++ + +++ + + KH + + + TL +K E+ V
Sbjct: 1325 LSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIA-------TLHAQVADMKKKMEDSV 1377
Query: 892 K-EERRQQLRRKVVEILPDFQVPGRYHELYQQSDTWSLSKTSLVNE 936
E ++++RK+ + L + R+ E D +KT L E
Sbjct: 1378 GCLETAEEVKRKLQKDLEG--LSQRHEEKVAAYDKLEKTKTRLQQE 1421
Score = 47.4 bits (111), Expect = 6e-05
Identities = 130/672 (19%), Positives = 274/672 (40%), Gaps = 98/672 (14%)
Query: 73 TDLKTSEQIEDHDEIYAE---AQELVNDW------LDTKLKQ---------ELASEEEGD 114
+D K+S+ +D + ++ QEL+ + L TKLKQ E EEE
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Query: 115 AKNTVSSVTIMPEANGHLKYDKFDDLCGYLEEEEE-STTVQKFIDHLLHKNVVDSAMMED 173
N + + +K K +D G LE EE +QK ++ L ++ A +
Sbjct: 1352 KHNLEKQIATLHAQVADMK-KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDK 1410
Query: 174 LGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQE 233
L ++ + + QQ+ L +++ H++ L ++++ + ++ L + + A+ E
Sbjct: 1411 L--EKTKTRLQQELDDLLVDLDHQRQSACNLEKKQK----KFDQLLAEEKTISAK--YAE 1462
Query: 234 EKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQS 293
E+ R EA+++E + + + E +E++ ++ K + R E SS+ + +S
Sbjct: 1463 ERDRAEAEAREKETKAL-SLARALEEAMEQKAELERLNK--QFRTEMEDLMSSKDDVGKS 1519
Query: 294 THILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDW 353
H L ++ ++++ ++K L + E Q + KL L+ ++ KA D
Sbjct: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDA------KLRLEVNLQAMKAQFERDL 1573
Query: 354 KIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLAT------EYNRKQVLRHCFT 407
+ R + + ++L R+ + +E +L +E +++ +A E + K + H +
Sbjct: 1574 QG-----RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
Query: 408 EWQHWHGAELLKRELALTKEETRKKMD--------ALLQAA-SLGKLSANGLSGISLPEE 458
++ A R+L ++ +++D L QA + KL + I L EE
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
Query: 459 ATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNK 518
A + QE L+ + ++ + L A
Sbjct: 1689 LAAAERAKRQAQQERDE---------------LADEIANSSGKGALALEEKRRLEA---- 1729
Query: 519 QHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTIL 578
+ L E ++ G+ E + +KA L + + ++ +K + Q+ ++
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKAN-LQIDQINTDLNLERSHAQKNENARQQLERQNK 1788
Query: 579 ELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSR 638
ELK LQ E +++ ++T ++ + + + T + +
Sbjct: 1789 ELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET-----------------KERQ 1831
Query: 639 NSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQ 698
+ +RR K+L +L+ +ER + AE + A+K + ++ QL+ EEE Q
Sbjct: 1832 AACKQVRRTEKKLKDV--LLQVDDER--RNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ 1887
Query: 699 KREAEEKEAQLE 710
+ A ++ Q E
Sbjct: 1888 RANASRRKLQRE 1899
Score = 46.6 bits (109), Expect = 1e-04
Identities = 132/682 (19%), Positives = 260/682 (38%), Gaps = 99/682 (14%)
Query: 144 LEEEEESTTVQKFID-------HLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRH 196
LE+ +ST Q+ + ++L K + + A + +E + K Q L ++
Sbjct: 1148 LEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQ 1207
Query: 197 -KQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQ-REMV 254
K+VK N + ++ LE +R E + L+ + E KRK +EA+ +E +++ E
Sbjct: 1208 TKRVKANLEKAKQTLENERGELANEVKVLLQGKG--DSEHKRKKVEAQLQELQVKFNEGE 1265
Query: 255 KLRREIIERRRTVKAAW--------KIEKKRQEENSQNSSEKVMFQSTHILPDEE----- 301
++R E+ ++ ++ + + K + S+ + Q T L EE
Sbjct: 1266 RVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKL 1325
Query: 302 ------KMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKI 355
K V++ K +E L + + +K+ A H + D + K+ + +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQ-IATLHAQVADMKKKMEDSVGCLETAE 1384
Query: 356 QLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLA--TEYNRKQVLRHCFTEWQHWH 413
++K +KL+++ + L E+ T+ +Q L + H
Sbjct: 1385 EVK-----------RKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDH-- 1431
Query: 414 GAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQET 473
+R+ A E+ +KK D LL +S E A K +
Sbjct: 1432 -----QRQSACNLEKKQKKFDQLLAEEKT-------ISAKYAEERDRAEAEAREKETKAL 1479
Query: 474 AVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPG-NKQHKTLGAEPSQQPG 532
++ E+ + RT +L S +V S K + L + +
Sbjct: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
Query: 533 SNETLRTTSQKAEPLCLGHFHNRHVFQQQL---IEKQKKKLQEQQKTILELKKNLQLAEA 589
E L Q E L N + Q ++ + ++ +E++K ++ + ++
Sbjct: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
Query: 590 QWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPK 649
+ ++AV K E + + + ++S + R ++ L L+ + K
Sbjct: 1600 DERKQRSMAVAAR------KKLEMDLKDLEAHIDS-----ANKNRDEAIKQLRKLQAQMK 1648
Query: 650 QLMTPHPILKAMEERAIQRAECRRILAEKK---KKQEEEKLAQLKAQEE----ERQKREA 702
M E RA ILA+ K KK + + ++ QEE ER KR+A
Sbjct: 1649 D---------CMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699
Query: 703 EEKEAQLERKREEKRLKKMKELEKQKRIK-RNQQLEAIAKEHYERVLLRKKGLEPWKRLR 761
+++ +L + K LE+++R++ R QLE +E L L+
Sbjct: 1700 QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK------ 1753
Query: 762 MQSKQNIQVAEEHYSLFLQRKY 783
K N+Q+ + + L L+R +
Sbjct: 1754 ---KANLQIDQINTDLNLERSH 1772
Score = 40.0 bits (92), Expect = 0.010
Identities = 55/214 (25%), Positives = 95/214 (44%), Gaps = 29/214 (13%)
Query: 562 LIEKQKKKLQEQQKTILELKKN----LQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRT 617
L K K Q+Q + L++N L+L QW + LL R+EE
Sbjct: 794 LARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQW-----WRLFTKVKPLLQVSRQEE--- 845
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTP----HPILKAMEERAIQRAECRR 673
+M+ E + + N L+ + QLM L+A E + E R
Sbjct: 846 -EMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRA 904
Query: 674 ILAEKKKKQEE---EKLAQLKAQEEERQKREAEEKEAQ-----LERKREEKRLKKMK-EL 724
L KK++ EE + A+++ +EE Q +AE+K+ Q LE + EE+ + K +L
Sbjct: 905 RLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQL 964
Query: 725 EK---QKRIKRNQQLEAIAKEHYERVLLRKKGLE 755
EK + ++K+ ++ + I ++ ++ KK LE
Sbjct: 965 EKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
Score = 34.3 bits (77), Expect = 0.56
Identities = 52/232 (22%), Positives = 100/232 (43%), Gaps = 41/232 (17%)
Query: 176 RKENQDKKQQKDPRLTMEMRHKQVKENRLRR-EKELEYQRIEKTLKKSAFLEAQCLVQEE 234
R E D+ + + + K+ E R+ + E+ELE ++ L +A + +
Sbjct: 1703 RDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQI 1762
Query: 235 KKRKALE---AKKEE---EEIQREMVKLRREIIERRRTVKAAWK-----IEKKRQEENSQ 283
LE A+K E ++++R+ +L+ ++ E TVK+ +K +E K + Q
Sbjct: 1763 NTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
Query: 284 NSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIK 343
+E Q+ K V+ ++KLK+VL+Q E + ++ ++ +
Sbjct: 1823 LDNETKERQAAC------KQVRRTEKKLKDVLLQVDDERRNAEQ------------YKDQ 1864
Query: 344 LGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATE 395
KA T +LK L+ + ++ E E Q R+ R+ + ATE
Sbjct: 1865 ADKAST------RLKQLK-----RQLEEAEEEAQRANASRRKLQRELEDATE 1905
Score = 33.5 bits (75), Expect = 0.95
Identities = 39/157 (24%), Positives = 73/157 (46%), Gaps = 27/157 (17%)
Query: 658 LKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKR 717
+ A EE ++ E +++ AE + + E +QL A++ + Q E+ +A+ E E +
Sbjct: 847 MMAKEEELVKVRE-KQLAAENRLTEMETLQSQLMAEKLQLQ----EQLQAETELCAEAEE 901
Query: 718 LKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSL 777
L+ +KQ+ + LEA +E ER + L+ K+ + +QNIQ EE
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERC----QHLQAEKK---KMQQNIQELEE---- 950
Query: 778 FLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRV 814
Q +E AR+ Q ++ ++ LK++
Sbjct: 951 -----------QLEEEESARQKLQLEKVTTEAKLKKL 976
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 63.9 bits (154), Expect = 7e-10
Identities = 122/569 (21%), Positives = 215/569 (37%), Gaps = 102/569 (17%)
Query: 230 LVQEEKKRKALEAKKEEEEI-----QREMVKLRREIIERRRTVKAAW-KIEKKRQEENSQ 283
L +E++R A E ++E E+ Q+ + K +R ++ + ++ W K+E++RQ E+ +
Sbjct: 49 LKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQK 108
Query: 284 NSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIK 343
++ + ++ ++E + +L+ ++ ++ + QQ + + +W +
Sbjct: 109 RAA---------VEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGA-----PLA 154
Query: 344 LGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQAL----ENDLREENRKQQLATEYNRK 399
+G G + KL T +L E + + +A Y+
Sbjct: 155 IGPGG-----------------HDACDKLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPD 197
Query: 400 QVLRHCFTEWQHWHGAELLKRELALTKEETR---KKMDALLQAASLGKLSANGLSGISLP 456
+V C A L + TR KK + G + LSG
Sbjct: 198 RVFHVCPRL------APLGPLNPSYKSSPTRNIEKKKATSTSTSGAGDVGKEALSG---- 247
Query: 457 EEATAMVGPPVKNGQETA--------------------VPPLWEKPPLGSSGCMLSPPLG 496
A + VK GQ TA +P P + + P
Sbjct: 248 --GEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGIPKRPSSPVISKTATKAYPQSP 305
Query: 497 RTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRH 556
+TT GS L A + AE ++ + E T +Q+A +H
Sbjct: 306 KTTKPPYPGSPVKYRLPALSGQDMPKRKAE--KEKSNKEREGTLAQQAAGPQGEEALEKH 363
Query: 557 VFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPR 616
V + EK + + L K A LA Q+ L K +EE+ R
Sbjct: 364 VVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARL-QKEQEEQER 422
Query: 617 TCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQ--LMTPHPILKAMEERAIQRAECRRI 674
E R L+RK ++ L K EER Q E ++
Sbjct: 423 V--------------EKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQ 468
Query: 675 LAEKKKKQEEEKLAQLKAQEEE--RQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKR 732
E+K+K EE A+ KA+EE ++K+E E++E + K++E K +E+ +Q R++R
Sbjct: 469 EGEEKRKAGEE--AKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLER 526
Query: 733 NQQLEAIAKEHYERVLLRKKGLEPWKRLR 761
Q + I +E ER +K+ E KR R
Sbjct: 527 EQIMLQIEQERLER---KKRIDEIMKRTR 552
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/145 (31%), Positives = 78/145 (53%), Gaps = 18/145 (12%)
Query: 670 ECRRILAEKK------KKQEEEKLAQLKAQ---EEERQKREAEEKEAQLE---RKREEKR 717
E +ILAEK+ K+QEE++ + + Q E E KR+AEE+ +LE RK+EE+R
Sbjct: 399 EAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEER 458
Query: 718 LKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQ----NIQVAEE 773
++ +E +KQ+ ++ + E ++ E +LL++K + + M KQ + E
Sbjct: 459 KRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREV 518
Query: 774 HYSLFLQRKYMLTWFQRSQESLARK 798
+ L+R+ ++ Q QE L RK
Sbjct: 519 AEQMRLEREQIM--LQIEQERLERK 541
Score = 50.4 bits (119), Expect = 8e-06
Identities = 39/149 (26%), Positives = 80/149 (53%), Gaps = 4/149 (2%)
Query: 176 RKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEK 235
R+ K+Q++ R+ E + + +E L+R+ E E R+E+ +K E + +E+K
Sbjct: 409 RQARLQKEQEEQERVEKEEQDRLEREE-LKRKAEEERLRLEEEARKQE-EERKRQEEEKK 466
Query: 236 KRKALEAKKEEEEIQR--EMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQS 293
K++ E +K EE +R E L +E E+ + KA + +K+ E ++ +E++ +
Sbjct: 467 KQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLER 526
Query: 294 THILPDEEKMVKERKRKLKEVLIQTFKEN 322
I+ E+ ERK+++ E++ +T K +
Sbjct: 527 EQIMLQIEQERLERKKRIDEIMKRTRKSD 555
Score = 48.5 bits (114), Expect = 3e-05
Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 640 SLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQK 699
SL G +P + T P + +++ R+ LA++++++ E+ LA + Q E+QK
Sbjct: 22 SLPGKIAEPGAVRTSQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQK 81
Query: 700 REAEEKEAQLE---------RKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYER 746
R + E Q+E R+RE+++ ++E KQK + ++LEA+ + ER
Sbjct: 82 RARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLER 137
Score = 45.8 bits (107), Expect = 2e-04
Identities = 33/110 (30%), Positives = 63/110 (57%), Gaps = 13/110 (11%)
Query: 630 GTEG--RSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKL 687
G EG +SD R L+ RR+ ++ L A E++ +++ + R+ EK+ ++ KL
Sbjct: 44 GMEGFLKSDERQRLAKERREERE-----KCLAAREQQILEKQKRARLQYEKQMEERWRKL 98
Query: 688 AQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLE 737
+ + +E+ QKR A E++ + + + EE+RL+ M ++ ++R QQLE
Sbjct: 99 EEQRQRED--QKRAAVEEKRKQKLREEEERLEAMM----RRSLERTQQLE 142
Score = 39.3 bits (90), Expect = 0.017
Identities = 55/208 (26%), Positives = 97/208 (46%), Gaps = 41/208 (19%)
Query: 146 EEEESTTVQKFI----DHLLHKNVVDSAMMEDL-----GRKEN-----QDKKQQKDPRLT 191
+E E T Q+ + L K+VVD E G+ EN + D
Sbjct: 341 KEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEA 400
Query: 192 MEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQR 251
++ ++ ++ RL++E+E E +R+EK E L +EE KRKA E + EE
Sbjct: 401 AKILAEKRRQARLQKEQE-EQERVEKE-------EQDRLEREELKRKAEEERLRLEE--- 449
Query: 252 EMVKLRREIIERRRTVKAAWKIEKKRQE-ENSQNSSEKVMFQSTHILPDEEKMVKER--K 308
+ R++ ER+R + EKK+QE E + + E+ ++ +EE ++KE+ +
Sbjct: 450 ---EARKQEEERKRQEE-----EKKKQEGEEKRKAGEEAKRKA-----EEELLLKEKQEQ 496
Query: 309 RKLKEVLIQTFKENQQCQKRYFAAWHKL 336
K ++ +I+ KE + + R A +L
Sbjct: 497 EKQEKAMIEKQKEAAETKAREVAEQMRL 524
Score = 38.5 bits (88), Expect = 0.030
Identities = 34/142 (23%), Positives = 67/142 (47%), Gaps = 10/142 (7%)
Query: 172 EDLGRKENQDKKQQ-KDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCL 230
E+ R+E + KKQ+ ++ R E ++ +E L +EK+ E+ ++ A +E Q
Sbjct: 456 EERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQ------EQEKQEKAMIEKQKE 509
Query: 231 VQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQ-EENSQNSSEKV 289
E K R+ E + E E + M+++ +E +ER++ + K +K + KV
Sbjct: 510 AAETKAREVAEQMRLERE--QIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKEDPKV 567
Query: 290 MFQSTHILPDEEKMVKERKRKL 311
Q + + K+V K ++
Sbjct: 568 GVQPAVCVEKKTKLVVPNKMEI 589
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 63.5 bits (153), Expect = 9e-10
Identities = 194/902 (21%), Positives = 356/902 (39%), Gaps = 173/902 (19%)
Query: 37 SVEHW------------IKRVEKASEFAVSNAFFTRNSDLPRSPWGQITDLKTSEQIEDH 84
+V+HW +K E E A F + D +L SE
Sbjct: 824 NVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKD----------ELAKSEA--KR 871
Query: 85 DEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYL 144
E+ + LV + D +L+ + SE DA+ + +A L+ K ++
Sbjct: 872 KELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLI---KAKFQLEA-KIKEVTERA 927
Query: 145 EEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEM--RHKQVKEN 202
E+EEE N +A L + ++ KK D LT+ + K EN
Sbjct: 928 EDEEEI-------------NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 974
Query: 203 RLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIE 262
+++ E E +++T+ K L + +E ++AL+ + EE+ + K + ++ +
Sbjct: 975 KVKNLTE-ELSGLDETIAK---LTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQ 1030
Query: 263 RRRTVKAAWKIEKKRQEENSQNSSE-----KVMFQSTHILPDEEKMVKER--KRKLKEVL 315
+ ++++ + EKK + + +N + K+ +S L ++++ + ER K+ +
Sbjct: 1031 QVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQ 1090
Query: 316 IQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLE-- 373
+Q+ E++Q F +IK +A + + + +++ RA R T Q+ +
Sbjct: 1091 LQSKVEDEQTLGLQF--------QKKIKELQA-RIEELEEEIEAERATRAKTEKQRSDYA 1141
Query: 374 RETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKM 433
RE + L L E E N+K+ AE LK L EE +
Sbjct: 1142 RELEELSERLEEAGGVTSTQIELNKKRE-------------AEFLKLRRDL--EEATLQH 1186
Query: 434 DALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSP 493
+A++ A+L K A ++ A +G + N Q EK
Sbjct: 1187 EAMV--AALRKKHA----------DSVAELGEQIDNLQRVKQKLEKEKSEF--------- 1225
Query: 494 PLGRTTTGNLQGSLQNVSLSAPG-NKQHKTLGAEPSQQPGSNETLR------TTSQKAEP 546
+ +L S+++VS S K +TL + S+ G NE ++ TT +
Sbjct: 1226 ---KLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQ 1282
Query: 547 LCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLA-EAQWAAEHALAVTEAQSH 605
G + ++ ++ + + Q + ELK+ L+ +A+ A HAL +
Sbjct: 1283 TEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCD 1342
Query: 606 LLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERA 665
LL + EEE EG+++ + +LS + Q T + E A
Sbjct: 1343 LLREQYEEEQ----------------EGKAELQRALSKANSEVAQWRTKY------ETDA 1380
Query: 666 IQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELE 725
IQR E + ++ ++KLAQ + Q+ E Q K A LE+ ++ RL+ E +
Sbjct: 1381 IQRTE--------ELEEAKKKLAQ-RLQDSEEQVEAVNAKCASLEKTKQ--RLQGEVE-D 1428
Query: 726 KQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVA-EEHYSLFLQRKYM 784
++R L A + K L WK +S+ ++ + +E SL
Sbjct: 1429 LMVDVERANSLAAALDKKQRNF---DKVLAEWKTKCEESQAELEASLKESRSL------- 1478
Query: 785 LTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKF--CVHFLQKKIF 842
S E K A + +KR ++ Q + DL E++ + +H L+K
Sbjct: 1479 ------STELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSR- 1531
Query: 843 RAWFNMVREVKIDSQ---GKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQL 899
+ K D Q + E A EH + +IL I L + + ++ K+E +QL
Sbjct: 1532 ----KQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQL 1587
Query: 900 RR 901
+R
Sbjct: 1588 KR 1589
Score = 38.5 bits (88), Expect = 0.030
Identities = 47/248 (18%), Positives = 113/248 (45%), Gaps = 20/248 (8%)
Query: 87 IYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYLEE 146
+ AE +EL T+ ++LA +E D+ V + + H K DL E
Sbjct: 1682 LQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSE 1741
Query: 147 EEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRR 206
E+++ + + K + D+AMM + +KE + + +E K + ++RL
Sbjct: 1742 VEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL-QHRLDE 1800
Query: 207 EKEL-------EYQRIEKTLKKSAF-LEAQCLVQEEK-------KRKALEAKKEEEEIQR 251
++L + Q++E +++ F LE + E +R+ E + EE ++
Sbjct: 1801 AEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRK 1860
Query: 252 EMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMF-QSTHILPDEEKMVKERKRK 310
+++L ++++++ + ++K ++ +E + Q ++ F ++ H L + E+ + +
Sbjct: 1861 NVLRL-QDLVDKLQVKVKSYK--RQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQ 1917
Query: 311 LKEVLIQT 318
+ ++ +T
Sbjct: 1918 VNKLRAKT 1925
Score = 35.0 bits (79), Expect = 0.33
Identities = 146/791 (18%), Positives = 319/791 (40%), Gaps = 134/791 (16%)
Query: 84 HDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGY 143
H + AE E +++ K K E +E+ + K + ++ E+ K + + +C
Sbjct: 1197 HADSVAELGEQIDNLQRVKQKLE---KEKSEFKLEIDDLSSSMESVSKSKAN-LEKICRT 1252
Query: 144 LEEE-----EESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQ 198
LE++ ++ +Q+ + L + S + + G Q ++K+ ++ R KQ
Sbjct: 1253 LEDQLSEARGKNEEIQRSLSELTTQK---SRLQTEAGELSRQ--LEEKESIVSQLSRSKQ 1307
Query: 199 VKENRLRREKELEYQRIEKTLKKSAFLEA------QCLVQEEKKRKALEAKKEEEEIQRE 252
++ +EL+ Q E+ K+A A C + E+ + E K E +QR
Sbjct: 1308 AFT---QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAE---LQRA 1361
Query: 253 MVKLRREIIERRR-----TVKAAWKIE--KKRQEENSQNSSEKVMFQSTHILPDEEKMVK 305
+ K E+ + R ++ ++E KK+ + Q+S E+V + EK +
Sbjct: 1362 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCA-SLEKTKQ 1420
Query: 306 ERKRKLKEVLIQTFKEN---------QQCQKRYFAAWHKLILDHRIKLG----KAGTLSD 352
+ +++++++ + N Q+ + A W + + +L ++ +LS
Sbjct: 1421 RLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480
Query: 353 WKIQLKVLRAWRD-YTRFQKLERETQALENDLRE------ENRKQQLATEYNRKQV---- 401
+LK A+ + + + ++RE + LE ++ + EN K E +RKQ+
Sbjct: 1481 ELFKLK--NAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEK 1538
Query: 402 ------LRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISL 455
L +H A++L+ +L LT+ ++ + + +L N +
Sbjct: 1539 ADIQLALEEAEAALEH-EEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVET 1597
Query: 456 PEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTG-----NLQGSLQNV 510
+ A + V++ E + L LS + ++QG L++
Sbjct: 1598 MQSA---LDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 1654
Query: 511 SLSAPG--------NKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQL 562
L +Q + + E LR T ++ E R + +Q+L
Sbjct: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE-------RARKLAEQEL 1707
Query: 563 IEKQKKK--LQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQM 620
++ ++ L Q +++ KK L+ Q +E A +A R E + +
Sbjct: 1708 LDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDA--------RNAEEKAKKA 1759
Query: 621 LVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKK 680
+ ++ + + + D+ L +++ +Q + K ++ R + AE + KK+
Sbjct: 1760 ITDAAMMAEELKKEQDTSAHLERMKKNLEQTV------KDLQHR-LDEAEQLALKGGKKQ 1812
Query: 681 KQE-EEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAI 739
Q+ E ++ +L+ + E QK+ E + ++ E+R+K++ ++ R
Sbjct: 1813 IQKLETRIRELEFELEGEQKKNTESVKGL---RKYERRVKELTYQSEEDR---------- 1859
Query: 740 AKEHYERVLLRKKGLEPWKRLRMQS-KQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARK 798
+ +LR + L +++++S K+ + A+E Q LT F+++Q L
Sbjct: 1860 ------KNVLRLQDLVDKLQVKVKSYKRQAEEADE------QANAHLTKFRKAQHELEEA 1907
Query: 799 MAQADQFYSQI 809
+AD SQ+
Sbjct: 1908 EERADIAESQV 1918
Score = 33.9 bits (76), Expect = 0.73
Identities = 74/423 (17%), Positives = 164/423 (38%), Gaps = 57/423 (13%)
Query: 38 VEHWIKRVEKASEFAVSNAFFTRNSDLPRSPWGQITDLKTSE---QIEDHDEIYAEAQEL 94
VE + VE+A+ A + RN D + W + +E +++ + E +L
Sbjct: 1426 VEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKL 1485
Query: 95 VNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQ 154
N + + + E E + + ++ +T NG ++ LE+ + ++
Sbjct: 1486 KNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHE--------LEKSRKQIELE 1537
Query: 155 KFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELE--- 211
K D L ++A+ + ++ K R+ +E+ + + +R EK+ E
Sbjct: 1538 K-ADIQLALEEAEAAL----------EHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQ 1586
Query: 212 ----YQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMV-KLRREIIERRRT 266
YQR +T++ + E + + + +K +E E EIQ + E ++ R+
Sbjct: 1587 LKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRS 1646
Query: 267 VKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQ 326
V+ K + ++ + + E+ + ER+ L + ++ + +
Sbjct: 1647 VQGQLKDTQLHLDDALRGQEDL----------KEQLAIVERRANLLQAEVEELRATLEQT 1696
Query: 327 KRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREE 386
+R + +LD ++ T + I K +KLE + L++++ +
Sbjct: 1697 ERARKLAEQELLDSNERVQLLHTQNTSLIHTK-----------KKLETDLMQLQSEVEDA 1745
Query: 387 NRKQQLATEYNRKQV------LRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAA 440
+R + A E +K + E E +K+ L T ++ + ++D Q A
Sbjct: 1746 SRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLA 1805
Query: 441 SLG 443
G
Sbjct: 1806 LKG 1808
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 62.4 bits (150), Expect = 2e-09
Identities = 65/261 (24%), Positives = 122/261 (46%), Gaps = 18/261 (6%)
Query: 172 EDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLV 231
E++ R+E + +Q++ R +M H+Q E ++R+++E +++ EK ++ E +
Sbjct: 476 EEMWRQEEKIHEQEEIWRQKEKM-HEQ--EEKIRKQEEKVWRQEEKIREQ----EEKIRE 528
Query: 232 QEEKKRKALEAKKEEEEIQREMVKLRR-----EIIERRRTVKAAWKIEKK--RQEENSQN 284
QEEK + E +E+EE+ RE K+ E +R+ W+ E+K QEE
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR 588
Query: 285 SSEKVMFQSTHILPDEEKMVK-ERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIK 343
EK+ Q EEKM K E K + +E IQ +E + Q+ ++ + K
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648
Query: 344 LGKAGTL---SDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQ 400
+G+ + K+Q + WR + ++ E++ + E +RE+ Q E +Q
Sbjct: 649 MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 708
Query: 401 VLRHCFTEWQHWHGAELLKRE 421
+ C E + E ++R+
Sbjct: 709 EEKMCEQEEKMQEQEEKMRRQ 729
Score = 61.6 bits (148), Expect = 3e-09
Identities = 56/252 (22%), Positives = 115/252 (45%), Gaps = 19/252 (7%)
Query: 166 VDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQV-----KENRLRREKELEYQRIEKTLK 220
++ M E +E ++K+Q+++ E R +Q +E ++R ++E ++ +K +
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 221 KSAFLEAQCLVQEEKKRKALEAK-------KEEEEIQREMVKLRREIIERRRTVKAAWKI 273
+ + Q ++EE+KR+ E E+EEI R+ K+ + + R+ + W+
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 274 EKK--RQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFA 331
E+K QEE + EK+ Q I EE +E K +E + + K +Q K +
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW-- 573
Query: 332 AWHKLILDHRIKLGKAGTL---SDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENR 388
+ I + K+ + + K Q + + W+ + ++ E + Q E +RE+
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEE 633
Query: 389 KQQLATEYNRKQ 400
K + E ++Q
Sbjct: 634 KIREQEEMTQEQ 645
Score = 60.5 bits (145), Expect = 7e-09
Identities = 55/274 (20%), Positives = 126/274 (45%), Gaps = 44/274 (16%)
Query: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFL---------EA 227
+E ++K ++++ ++ + KE ++RR++E+ +++ EK ++ + +
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 383
Query: 228 QCLVQEEKKRKALEAKKEEEEIQREMVKLR------REIIERRRTVKAAWKIEKK-RQEE 280
+ + ++E+K + LE K E+E RE + R RE +R+ W+ E+K R++E
Sbjct: 384 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 443
Query: 281 NSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDH 340
EK M++ + ++EK+ +E KR+ +E + +++ ++ ++ W + H
Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE---EMWRQEEKIHEQE-EIWRQKEKMH 499
Query: 341 RIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQ 400
+ KI+ + + WR E + + E +RE+ K E R+Q
Sbjct: 500 E---------QEEKIRKQEEKVWRQ-------EEKIREQEEKIREQEEKMWRQEEKIREQ 543
Query: 401 VLRHCFTEWQHWHGAELLKRELALTKEETRKKMD 434
+ W E + + + +EE R++ +
Sbjct: 544 E--------EMWREEEKMHEQEKIWEEEKRQEQE 569
Score = 56.2 bits (134), Expect = 1e-07
Identities = 75/372 (20%), Positives = 160/372 (43%), Gaps = 58/372 (15%)
Query: 75 LKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKY 134
L+ ++ + ++ AEA L + K + A EE + N ++ E +
Sbjct: 251 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQ-AQVEENELWNRLNQ---QQEEKMWRQE 306
Query: 135 DKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQ-----KDPR 189
+K + ++E+EE Q+ + + + E + KE + ++Q+ K+ +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 190 LTMEMRHKQVKENRLRREKELEYQRIEKT--LKKSAFLEAQCLVQEEK-----------K 236
+ + KE ++RR++E+ +++ EK L++ + + QEEK K
Sbjct: 365 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 424
Query: 237 RKALEAK--KEEEEIQREMVKLRRE------------------IIERRRTVKAAWKIEKK 276
R+ EAK ++EE+I+ + K+R + E+R+ + W+ E+K
Sbjct: 425 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 484
Query: 277 --------RQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKR 328
RQ+E EK+ Q + EEK ++E++ K++E + +++ ++ +++
Sbjct: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK-IREQEEKIREQEEKMWRQEEKIREQ 543
Query: 329 YFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENR 388
W + H + + K Q + + WR + ++ E + E +RE+
Sbjct: 544 E-EMWREEEKMHE----QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 389 KQQLATEYNRKQ 400
K+Q E KQ
Sbjct: 599 KRQEQEEKMWKQ 610
Score = 56.2 bits (134), Expect = 1e-07
Identities = 71/394 (18%), Positives = 177/394 (44%), Gaps = 56/394 (14%)
Query: 518 KQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTI 577
K+ +++ A+ Q NE +Q+ E + Q++ I++ ++K+QEQ++ I
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQE--------EKMWRQEEKIQEWEEKIQEQEEKI 323
Query: 578 LELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDS 637
E ++ ++ E + Q ++ + E+ R +M+
Sbjct: 324 REQEEKIREQEEKM---------RRQEEMMWEKEEKMRRQEEMMWEKE------------ 362
Query: 638 RNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEER 697
+RR+ + + ++ EE ++ E R L EK +QE+ + + K QEEE+
Sbjct: 363 ----EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418
Query: 698 QKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPW 757
+ + + +E + + R+E+++++ +E +++ K +Q E I ++ E++ +K E
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ--EKIREEEKRQEQE 476
Query: 758 KRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQ--RSQESLARKMAQADQFYSQILLKRVI 815
+ R + K E ++ Q++ M + R QE + + + + + ++
Sbjct: 477 EMWRQEEK-----IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531
Query: 816 QSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAE---HSDRRIL 872
+ W Q +E++R+ Q++++R M + KI + K + + + +I
Sbjct: 532 KMWRQ-----EEKIRE------QEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 873 WITLRTWKKFVKFMKEERVKEERRQQLRRKVVEI 906
+ W++ K ++E ++E+ +++ ++ +I
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Score = 53.9 bits (128), Expect = 7e-07
Identities = 47/239 (19%), Positives = 112/239 (46%), Gaps = 11/239 (4%)
Query: 75 LKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKY 134
++ E+ ++ +E++ + +++ + K+++ +EE K E +
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ--EEKVWRQEEKIREQE 523
Query: 135 DKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEM 194
+K + + +EE Q+ + K + E+ R+E +DK +++ ++ +
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 195 RHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMV 254
+E ++R ++E ++ EK K+ E + QEEK ++ E +E+EE RE
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQ----EEKIREQEEKIQEQEEKIREQEEKIREQE 639
Query: 255 KLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKE 313
++ +E E K + EK ++E E+ M++ + ++EK ++E++ K++E
Sbjct: 640 EMTQEQEE-----KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693
Score = 48.1 bits (113), Expect = 4e-05
Identities = 65/344 (18%), Positives = 149/344 (43%), Gaps = 42/344 (12%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
Q+ + +Q++K++EQ++ I E +K + W E + H K REEE R
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKM------WRQEEKI-------HEQEKIREEEKRQE 474
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
Q + + + + + +++ + EE+ ++ E R EK
Sbjct: 475 QEEMWRQEEK--IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Query: 679 KKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEA 738
+QEE+ Q + EE + E E+ + +R+ +E ++ + +E +++ K +Q E
Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
Query: 739 IAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARK 798
I ++ +R +++ + WK+ +Q ++ E+ + Q + + + +QE +
Sbjct: 593 IREQEEKR---QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 799 MAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQG 858
Q ++ Q + +Q + + +E++R+ Q+K R +RE + Q
Sbjct: 650 GEQEEKMCEQ---EEKMQEQEETMWRQEEKIRE------QEKKIREQEEKIREQEEMMQE 700
Query: 859 KHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRK 902
+ E + W++ K ++E +E+ +++RR+
Sbjct: 701 QEE---------------KMWEQEEKMCEQEEKMQEQEEKMRRQ 729
Score = 47.4 bits (111), Expect = 6e-05
Identities = 48/228 (21%), Positives = 106/228 (46%), Gaps = 4/228 (1%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
Q++ + +Q++K++EQ++ I E ++ + E + + + E + H K EEE R
Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
Q E +R + ++ + EE+ ++ E + EK
Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Query: 679 KKKQEEEKLAQLK-AQEEERQKREAEEKEAQLERKREEKRLKKMKELEK-QKRIKRNQQL 736
++QEE+ Q + QE+E + E EEK + E K +E+ ++ EK +++ K+ ++
Sbjct: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687
Query: 737 EAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYM 784
E +E E +++++ + W++ +Q ++ E+ + Q + M
Sbjct: 688 EEKIREQEE--MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
Score = 43.9 bits (102), Expect = 7e-04
Identities = 35/140 (25%), Positives = 69/140 (49%), Gaps = 6/140 (4%)
Query: 176 RKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFL---EAQCLVQ 232
R+E ++K +++ ++ + Q +E ++R ++E ++ E T ++ + E + Q
Sbjct: 600 RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 659
Query: 233 EEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKR---QEENSQNSSEKV 289
EEK ++ E +EE RE K RE E+ R + + ++++ QEE EK+
Sbjct: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
Query: 290 MFQSTHILPDEEKMVKERKR 309
Q + EEKM ++ R
Sbjct: 720 QEQEEKMRRQEEKMWEQEVR 739
Score = 42.7 bits (99), Expect = 0.002
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 167 DSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLE 226
+ + E + Q++K ++ +T E K ++ E+E + Q E+T+ +
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR----- 672
Query: 227 AQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIER--RRTVKAAWKIEK-KRQEENSQ 283
QEEK R+ + +E+EE RE ++ +E E+ + K + EK + QEE +
Sbjct: 673 -----QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
Query: 284 NSSEKVMFQSTHILPDEEKM 303
EK+ Q + EEKM
Sbjct: 728 RQEEKMWEQEVRLRQQEEKM 747
Score = 42.4 bits (98), Expect = 0.002
Identities = 42/188 (22%), Positives = 87/188 (46%), Gaps = 15/188 (7%)
Query: 559 QQQLIEKQKKKLQEQQKTILELK-KNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRT 617
Q++ I +Q++K+ Q++ I E + K + E W E + E K +E+E +
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE------EKIQEQEEKI 628
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAE 677
+ T+ + + + ++ M +E I+ E ++I +
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE-KKIREQ 687
Query: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEK--QKRIKRNQQ 735
++K +E+E++ QE+E + E EEK + E K +E+ K ++ EK ++ ++ QQ
Sbjct: 688 EEKIREQEEM----MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 743
Query: 736 LEAIAKEH 743
E + +EH
Sbjct: 744 EEKM-QEH 750
Score = 40.0 bits (92), Expect = 0.010
Identities = 41/215 (19%), Positives = 99/215 (46%), Gaps = 17/215 (7%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
+Q+ + ++++K+ EQ+K I E +K + + W E + E + R+EE
Sbjct: 542 EQEEMWREEEKMHEQEK-IWEEEKRQEQEDKMWRQEEKIREQEEKVW-----RQEEKIRE 595
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
Q + R ++ + +++ ++ EE ++ E EK
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 679 KKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEA 738
+QEE +++ QEE ++E + +E + + + +E+++++ +E+ +++ K +Q E
Sbjct: 656 MCEQEE----KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
Query: 739 IA----KEHYERVLLRKKGLEPWK---RLRMQSKQ 766
+ K + +R++ + W+ RLR Q ++
Sbjct: 712 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 33.9 bits (76), Expect = 0.73
Identities = 51/285 (17%), Positives = 118/285 (41%), Gaps = 60/285 (21%)
Query: 662 EERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKM 721
E A+ R + +++ K++ KL +E+ Q E+E+ E QL K +++L++
Sbjct: 201 ERDALSLELYRNTITDEELKEKNAKL------QEKLQLVESEKSEIQLNVKELKRKLERA 254
Query: 722 KEL----------------------EKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR 759
K L + Q +++ N+ + ++ E++ +++ ++ W+
Sbjct: 255 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314
Query: 760 LRMQSKQNIQVAEE---HYSLFLQRKYMLTWFQ----RSQESL----ARKMAQADQFYSQ 808
+ ++ I+ EE ++R+ + W + R QE + KM + ++ +
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 374
Query: 809 ILLKRVIQSWLQY-----VIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGK---- 859
K Q + + + +L+E++ + Q+KI E KI Q K
Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHE------QEKIREQEEKRQEEEKIREQEKRQEQ 428
Query: 860 ------HEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQ 898
E + +I + W++ K ++E+++EE ++Q
Sbjct: 429 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 473
Score = 31.6 bits (70), Expect = 3.6
Identities = 26/116 (22%), Positives = 56/116 (48%), Gaps = 10/116 (8%)
Query: 172 EDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQ--RIEKTLKKSAFLEAQC 229
E++ +++ + +Q++ E + ++ +E R+E+++ Q +I + +K E
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Query: 230 LVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAW--KIEKKRQEENSQ 283
QEEK + E E+EE +E + + RR + W ++ ++QEE Q
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEE------KMRRQEEKMWEQEVRLRQQEEKMQ 748
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 62.4 bits (150), Expect = 2e-09
Identities = 149/698 (21%), Positives = 286/698 (40%), Gaps = 116/698 (16%)
Query: 78 SEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKF 137
+EQ++ E++AEA+E+ L K KQEL +
Sbjct: 893 AEQLQAETELFAEAEEM-RARLAAK-KQELE--------------------------EIL 924
Query: 138 DDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHK 197
DL +EEEEE + + + ++ D + E L +E +K Q + ++T E + K
Sbjct: 925 HDLESRVEEEEERNQILQNEKKKMQAHIQD--LEEQLDEEEGARQKLQLE-KVTAEAKIK 981
Query: 198 QVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLR 257
+++E L E + S F++ + L+ E++ + EEEE + + K+R
Sbjct: 982 KMEEEILLLEDQ-----------NSKFIKEKKLM-EDRIAECSSQLAEEEEKAKNLAKIR 1029
Query: 258 REIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQ 317
++ V + E+ ++EE ++ EK + D + + E + ++ E+ +Q
Sbjct: 1030 -----NKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQ 1084
Query: 318 TFKENQQCQKRYFAAWHK-LILDHRIKLGK--AGTLSDWKIQLKVLRAWRDYTRFQK--L 372
K+ ++ Q + L ++ +K+ + +++ + + +A R+ QK L
Sbjct: 1085 LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDL 1144
Query: 373 ERETQALENDLRE----ENRKQQLATEYNRKQV-LRHCFTEWQHWHGAEL--LKRELALT 425
E +AL+ +L + +Q+L T+ ++ L+ E H A++ +++ A
Sbjct: 1145 SEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATA 1204
Query: 426 KEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPL----WEK 481
EE ++++ + + + + GL + V VK E L E
Sbjct: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 482 PPLGSSGCMLSPPLGRTTTGNLQGSLQNVS-----LSAPGNKQHKTLGAEPSQQPGSNET 536
S G L L + LQ L NVS G K K + SQ + E
Sbjct: 1265 HAKVSEGDRLRVELAEKAS-KLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1323
Query: 537 LRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNL---------QLA 587
L+ +++ L + + +E++K LQEQQ+ E +KNL QLA
Sbjct: 1324 LQEETRQKLNLS---------SRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLA 1374
Query: 588 EAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRK 647
+ + + L E+ K ++ Q L +A E
Sbjct: 1375 DTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLE--------------- 1419
Query: 648 PKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKE- 706
T + + + +++ + R++ + +KKQ +K QL A+E+ R AEE++
Sbjct: 1420 ----KTKNRLQQELDDLTVDLDHQRQVASNLEKKQ--KKFDQLLAEEKSISARYAEERDR 1473
Query: 707 AQLE-RKREEKRLKKMKELE-----KQKRIKRNQQLEA 738
A+ E R++E K L + LE K++ ++N+QL A
Sbjct: 1474 AEAEAREKETKALSLARALEEALEAKEEFERQNKQLRA 1511
Score = 50.1 bits (118), Expect = 1e-05
Identities = 178/852 (20%), Positives = 344/852 (40%), Gaps = 135/852 (15%)
Query: 84 HD-EIYAEAQELVNDWLDTKLKQELAS----EEEGDAKNTVSSVTIMPEANGHLKYDKFD 138
HD E E +E N L + K+ A EE+ D + + + K K +
Sbjct: 925 HDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKME 984
Query: 139 DLCGYLEEEEESTTVQKFIDHLLHKNVVD--SAMMEDLGRKENQDKKQQKDPRLTMEMRH 196
+ LE++ +K L+ + + S + E+ + +N K + K + ++
Sbjct: 985 EEILLLEDQNSKFIKEK---KLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEE 1041
Query: 197 KQVKENRLRREKELEYQRI--EKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMV 254
+ KE + R+E E +++ E T + E Q + E K L+ K+EEE+Q +
Sbjct: 1042 RLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK----LQLAKKEEELQGALA 1097
Query: 255 KLRREIIERRRTVKAAWKIEKK--------RQEENSQNSSEKV---MFQSTHILPDE--- 300
+ E + + +K +++ + E+ S+N +EK + + L E
Sbjct: 1098 RGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED 1157
Query: 301 ---------------EKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLI-------- 337
E+ V E K+ L+E + Q ++R+ A +L
Sbjct: 1158 TLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKR 1217
Query: 338 LDHRIKLGKAGTLSDWK---IQLKVL---RAWRDYTRFQKLERETQALENDLREENR-KQ 390
++ K G +D K ++KVL +A ++ R +KL+ + Q L + E +R +
Sbjct: 1218 FKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR-KKLDAQVQELHAKVSEGDRLRV 1276
Query: 391 QLATEYNRKQ-VLRHCFT--EWQHWHGAELLKRELALT----------KEETRKKMDALL 437
+LA + ++ Q L + T E G + K +L +EETR+K++
Sbjct: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 438 QAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGR 497
+ L + N L EE + E V L + L + + LG
Sbjct: 1337 RIRQLEE-EKNSLQEQQEEEEEA-------RKNLEKQVLALQSQ--LADTKKKVDDDLG- 1385
Query: 498 TTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHV 557
T +L+ + + + A Q L + +T Q+ + L + H R V
Sbjct: 1386 -TIESLEEAKKKLLKDAEALSQR--LEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQV 1442
Query: 558 FQQQLIEKQKK--KLQEQQKTILEL---KKNLQLAEAQWAAEHALAVTEAQSHLLSKPRE 612
L +KQKK +L ++K+I +++ AEA+ AL++ A L E
Sbjct: 1443 -ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEE 1501
Query: 613 EEPRTCQMLVNSP--VASPGTEGRS--DSRNSLSGLRRKPKQLMTP----HPILKAMEER 664
E + Q+ + ++S G++ + S L ++ +++ T L+A E+
Sbjct: 1502 FERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDA 1561
Query: 665 AIQ--------RAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEK 716
++ +A+ R L + ++ EE+K +K E + E E K+ L ++K
Sbjct: 1562 KLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKK 1621
Query: 717 RLKKMKELEKQ---------KRIKRNQQLEAIAKEHYERVL---------LRKKGLEPWK 758
+K+LE Q + IK+ ++L+A K+ Y+R L + + E K
Sbjct: 1622 MEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD-YQRELEEARASRDEIFAQSKESEK 1680
Query: 759 RLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQIL--LKRVIQ 816
+L+ + +Q+ EE S R++ ++ ++ LA ++ + S +L +R+
Sbjct: 1681 KLKSLEAEILQLQEELASSERARRHA----EQERDELADEITNSASGKSALLDEKRRLEA 1736
Query: 817 SWLQYVIDLQEE 828
Q +L+EE
Sbjct: 1737 RIAQLEEELEEE 1748
Score = 48.1 bits (113), Expect = 4e-05
Identities = 124/640 (19%), Positives = 249/640 (38%), Gaps = 84/640 (13%)
Query: 105 QELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKN 164
QE EEE KN V + K K DD G +E EE+ L +
Sbjct: 1349 QEQQEEEEEARKNLEKQVLALQSQLADTK-KKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407
Query: 165 VVDSAMMEDLGRKENQDKKQQKDPRLTMEMRH-KQVKENRLRREKELEYQRIEKTLKKSA 223
+ + A+ D K +Q+ D LT+++ H +QV N +++K+ + E+ +
Sbjct: 1408 LEEKALAYDKLEKTKNRLQQELDD-LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISAR 1466
Query: 224 FLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQ 283
+ E E+ R EA+++E + + + E +E + + K + R +
Sbjct: 1467 YAE-------ERDRAEAEAREKETKAL-SLARALEEALEAKEEFERQNK--QLRADMEDL 1516
Query: 284 NSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIK 343
SS+ + ++ H L ++ ++++ +++ L + E Q + KL L+ ++
Sbjct: 1517 MSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDA------KLRLEVNMQ 1570
Query: 344 LGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLR 403
KA D + R ++ + + L ++ + LE +L +E +++ LA +K
Sbjct: 1571 AMKAQFERDLQT-----RDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKM--- 1622
Query: 404 HCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMV 463
E+ ++L E K D +++ L KL A EEA A
Sbjct: 1623 ------------EIDLKDLEAQIEAANKARDEVIK--QLRKLQAQMKDYQRELEEARASR 1668
Query: 464 GPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTL 523
+E+ EK +L LQ S+ ++H
Sbjct: 1669 DEIFAQSKES------EKKLKSLEAEILQ--------------LQEELASSERARRH--- 1705
Query: 524 GAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQ-QQLIEKQKKKLQEQQKTILELKK 582
AE + ++E + S K+ L + Q ++ +E+++ ++ +
Sbjct: 1706 -AEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTL 1764
Query: 583 NLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLS 642
+ A+ AAE + A + + + +E + + V +S + ++S
Sbjct: 1765 QVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV-------KSKFKATIS 1817
Query: 643 GLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREA 702
L K QL EE+ Q A+ R A K ++ E+KL ++ Q E+ ++
Sbjct: 1818 ALEAKIGQL----------EEQLEQEAK-ERAAANKLVRRTEKKLKEIFMQVEDERRHAD 1866
Query: 703 EEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKE 742
+ KE + K+LK+ E +++ + N + +E
Sbjct: 1867 QYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRE 1906
Score = 43.1 bits (100), Expect = 0.001
Identities = 76/354 (21%), Positives = 146/354 (41%), Gaps = 41/354 (11%)
Query: 560 QQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQ 619
+Q +EK K+KL + + + LQ + + A E Q L E +
Sbjct: 1050 RQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNA 1109
Query: 620 MLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKK 679
+ V + + E + D + + + KQ L+A++ + E +
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELR 1169
Query: 680 KKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKE-LEKQKRIKRNQQLEA 738
K+E+E KA EEE + EA+ ++ R+R L+++ E LE+ KR K N +
Sbjct: 1170 TKREQEVAELKKALEEETKNHEAQIQDM---RQRHATALEELSEQLEQAKRFKANLE--- 1223
Query: 739 IAKEHYERVLLRKKGLE-PWKRLRMQSK--QNIQVAEEHYSLFLQRKYMLTWFQRSQESL 795
K+GLE K L + K Q ++ EH +RK + + L
Sbjct: 1224 ----------KNKQGLETDNKELACEVKVLQQVKAESEH-----KRKKL----DAQVQEL 1264
Query: 796 ARKMAQADQFYSQILLK-RVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKI 854
K+++ D+ ++ K +Q+ L V L EE K + F + ++
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD---------AASLES 1315
Query: 855 DSQGKHEIAAEHSDRRI-LWITLRTWKKFVKFMKEERVKEER-RQQLRRKVVEI 906
Q E+ E + +++ L +R ++ ++E++ +EE R+ L ++V+ +
Sbjct: 1316 QLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLAL 1369
Score = 40.8 bits (94), Expect = 0.006
Identities = 46/214 (21%), Positives = 92/214 (42%), Gaps = 29/214 (13%)
Query: 562 LIEKQKKKLQEQQKTILELKKN----LQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRT 617
L K K Q+Q + L++N L+L QW V LL R+EE
Sbjct: 801 LARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQW-----WRVFTKVKPLLQVTRQEE--- 852
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPIL----KAMEERAIQRAECRR 673
++ E ++ L + RK +QL+ IL +A E + E R
Sbjct: 853 -ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 911
Query: 674 ILAEKKKK------------QEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKM 721
LA KK++ +EEE+ Q+ E+++ + ++ E QL+ + ++ ++
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL 971
Query: 722 KELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLE 755
+++ + +IK+ ++ + ++ + + KK +E
Sbjct: 972 EKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Score = 36.2 bits (82), Expect = 0.15
Identities = 51/219 (23%), Positives = 97/219 (44%), Gaps = 39/219 (17%)
Query: 564 EKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTE-----------AQSHLLSKPRE 612
++ +KKL+ + IL+L++ +LA ++ A HA + +S LL + R
Sbjct: 1676 KESEKKLKSLEAEILQLQE--ELASSERARRHAEQERDELADEITNSASGKSALLDEKRR 1733
Query: 613 EEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECR 672
E R Q+ E +D R+ Q+ T + L A E A Q+++
Sbjct: 1734 LEARIAQLEEELEEEQSNMELLNDR------FRKTTLQVDTLNAELAA-ERSAAQKSDNA 1786
Query: 673 RILAEKKKKQEEEKLAQLKA------------------QEEERQKREAEEKEAQLER-KR 713
R E++ K+ + KL +L+ Q EE+ ++EA+E+ A + +R
Sbjct: 1787 RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRR 1846
Query: 714 EEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKK 752
EK+LK++ + +R +Q E + K + L+++
Sbjct: 1847 TEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQ 1885
Score = 36.2 bits (82), Expect = 0.15
Identities = 46/217 (21%), Positives = 92/217 (42%), Gaps = 23/217 (10%)
Query: 187 DPRLTMEMRHKQVKENRLRREKELEY--QRIEKTLKKSAFLEAQCLVQEEKKRKALEAKK 244
D + +E R Q++E + +E R KT + L A+ + +K+ A+
Sbjct: 1729 DEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNAR- 1787
Query: 245 EEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMV 304
++++R+ +L+ ++ E VK+ +K E E++ Q K+V
Sbjct: 1788 --QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLE-QEAKERAAANKLV 1844
Query: 305 KERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGT-LSDWKIQLKVLRAW 363
+ ++KLKE+ +Q E + + ++ ++ KA + K QL+ A
Sbjct: 1845 RRTEKKLKEIFMQVEDERRHADQ------------YKEQMEKANARMKQLKRQLE--EAE 1890
Query: 364 RDYTRFQKLERETQALENDLREENR--KQQLATEYNR 398
+ TR R+ Q +D E N ++++T NR
Sbjct: 1891 EEATRANASRRKLQRELDDATEANEGLSREVSTLKNR 1927
Score = 32.0 bits (71), Expect = 2.8
Identities = 52/248 (20%), Positives = 108/248 (43%), Gaps = 37/248 (14%)
Query: 656 PILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREE 715
P+L+ + +A+ +L K+K+ + E +L+ E + Q+ EEK E+ + E
Sbjct: 843 PLLQVTRQEEELQAKDEELLKVKEKQTKVE--GELEEMERKHQQL-LEEKNILAEQLQAE 899
Query: 716 KRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHY 775
L E + + + Q+LE I + RV ++ + + + + + +IQ EE
Sbjct: 900 TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE-- 957
Query: 776 SLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVH 835
Q +E AR+ Q ++ ++ +K++ + ++ L+++ KF
Sbjct: 958 -------------QLDEEEGARQKLQLEKVTAEAKIKKMEEE----ILLLEDQNSKF--- 997
Query: 836 FLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEER 895
+KK+ R + SQ AE ++ +R ++ + EER+K+E
Sbjct: 998 IKEKKLMED-----RIAECSSQ-----LAEEEEKAKNLAKIRNKQEVMISDLEERLKKEE 1047
Query: 896 --RQQLRR 901
RQ+L +
Sbjct: 1048 KTRQELEK 1055
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 60.8 bits (146), Expect = 6e-09
Identities = 46/225 (20%), Positives = 113/225 (50%), Gaps = 11/225 (4%)
Query: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKT--LKKSAFLEAQCLVQEE 234
+E ++K ++++ ++ + KE ++RR++E+ +++ EK L++ + + + + + E
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383
Query: 235 KKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQST 294
+K E +E+EE ++E K+R + + + K + EK R++E EK M++
Sbjct: 384 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 443
Query: 295 HILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTL---- 350
+ ++EK+ +E KR+ +E + + +E + Q+ + K+ +I+ +
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQ-EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE 502
Query: 351 ----SDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQ 391
+ KI+ + + WR + ++ E + + E +RE+ Q
Sbjct: 503 KMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQ 547
Score = 59.7 bits (143), Expect = 1e-08
Identities = 74/400 (18%), Positives = 185/400 (46%), Gaps = 47/400 (11%)
Query: 518 KQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTI 577
K+ +++ A+ Q NE +Q+ E + Q++ I++ ++K+QEQ++ I
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQE--------EKMWRQEEKIQEWEEKIQEQEEKI 323
Query: 578 LELKKNL--------QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASP 629
E ++ + + E W E + Q ++ + E+ R +M+
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKM---RRQEEMMWEKEEKMRRLEEMMWEKEEKIR 380
Query: 630 GTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQ 689
E + + + R+ ++ ++ E+R Q A+ R E+K +++EEK+
Sbjct: 381 ELEEKMHEQEKI----REQEEKRQEEEKIREQEKRQEQEAKMWR--QEEKIREQEEKI-- 432
Query: 690 LKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQ-KRIKRNQQLEAIAKEHYERVL 748
+E+E++ EEK + E+ REE++ ++ +E+ +Q ++I+ +++ ++ +E+
Sbjct: 433 ---REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK 489
Query: 749 LRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQ 808
+RK+ + W++ Q ++ E+ ++ Q + + R QE R+ Q ++ Q
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI-----REQEEKIRE--QEEKIREQ 542
Query: 809 ILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSD 868
+ ++Q + + + +E++++ Q++ R +RE K + + E E +
Sbjct: 543 ---EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 869 R------RILWITLRTWKKFVKFMKEERVKEERRQQLRRK 902
+ + + W++ K ++E +E+ +++RR+
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Score = 57.4 bits (137), Expect = 6e-08
Identities = 52/230 (22%), Positives = 104/230 (45%), Gaps = 10/230 (4%)
Query: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKK 236
+E ++K Q+++ ++ + + +E ++RR++E+ +++ EK ++ E +EEK
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ----EEMMWEKEEKM 365
Query: 237 RKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHI 296
R+ E E+EE RE+ + E + R + + EK R++E Q K+ Q I
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 297 LPDEEKMVKERKR------KLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTL 350
EEK+ ++ K+ K+ E +E +Q Q+ + K+ I K
Sbjct: 426 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMH 485
Query: 351 SDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQ 400
KI+ + + WR + E + + E + + K + E R+Q
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/289 (19%), Positives = 132/289 (45%), Gaps = 21/289 (7%)
Query: 145 EEEEESTTVQKFIDHLLHK-NVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENR 203
E+EE+ +++ + K ++ M E +E ++K+Q+++ E R +Q +
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419
Query: 204 LRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIER 263
+ EK E + + +K + + + + ++EK R+ E ++E+EE+ R+ K+R +
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE-EKRQEQEEMWRQEEKIREQ---- 474
Query: 264 RRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKL--KEVLIQTFKE 321
+ W+ ++K E+ E+ +++ + D+E+ ++E++ K+ +E I+ +E
Sbjct: 475 ----EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE 530
Query: 322 NQQCQKRYFAAWHKLILDHRIKLG----KAGTLSDWKIQLKVLRAWRDYTRFQK-----L 372
+ Q+ +++ + K+G K + Q + +R + R QK
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 373 ERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRE 421
E + E +RE+ Q E +Q + C E + E ++R+
Sbjct: 591 EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Score = 51.6 bits (122), Expect = 3e-06
Identities = 59/263 (22%), Positives = 116/263 (44%), Gaps = 17/263 (6%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKP--REEEPR 616
+Q+ I +Q++K QE++K I E +K + W E + E + K R+EE
Sbjct: 388 EQEKIREQEEKRQEEEK-IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 446
Query: 617 TCQMLVNSPVASPGTEGRSDSRNSLSGLRR--KPKQLMTPHPILKAMEERAIQRAECRRI 674
Q + E + + K+ M ++ EE+ ++ E
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD 506
Query: 675 LAEKKKKQ------EEEKLAQL--KAQEEERQKREAEEKEAQLERKREEKRLKKMKELEK 726
EK ++Q +EEK+ + K +E+E + RE EE + E K E+ +KM+E EK
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE-EKMQEQEK 565
Query: 727 QKRIKRN-QQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYML 785
+R + ++ E +E E++ R++ + W++ +Q + E+ ++ Q + M
Sbjct: 566 MRRQEEKIREQEEKIREQKEKI--REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623
Query: 786 TWFQRSQESLARKMAQADQFYSQ 808
++ QE + Q ++ + Q
Sbjct: 624 EQEEKMQEQEEKMRRQEEKMWEQ 646
Score = 50.8 bits (120), Expect = 6e-06
Identities = 51/281 (18%), Positives = 132/281 (46%), Gaps = 19/281 (6%)
Query: 644 LRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAE 703
+RR+ + + ++ +EE ++ E R L EK +QE+ + + K QEEE+ + + +
Sbjct: 351 MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 410
Query: 704 EKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQ 763
+E + + R+E+++++ +E +++ K +Q E I ++ R +++ E R +
Sbjct: 411 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Query: 764 SKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVI 823
++ ++ + + Q K R QE + + + + ++ + W Q
Sbjct: 471 IREQEEIWRQKEKMHEQEKI------RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ--- 521
Query: 824 DLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFV 883
+E++R+ Q++ R +RE + Q + E E ++ +R ++ +
Sbjct: 522 --EEKIRE------QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 884 KFMKEERVKEERRQQLRRKVVEILPDFQVPGRYHELYQQSD 924
+ +EE+++E+ ++++R + +I + E+ Q+ +
Sbjct: 574 R-EQEEKIREQ-KEKIREQEEKIWEQEEKIREQEEMMQEQE 612
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/192 (21%), Positives = 97/192 (50%), Gaps = 16/192 (8%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNL-QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRT 617
+Q+ I KQ++K+ Q++ + + ++ + + E W E + E + + +EE+ R
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI----REQEEKIRE 541
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAE 677
+ ++ G + + +RR+ +++ ++ +E+ ++ E +I +
Sbjct: 542 QEEMMQEQEEKMGEQ--EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE--KIWEQ 597
Query: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEK--QKRIKRNQQ 735
++K +E+E++ QE+E + E EEK + E K +E+ K ++ EK ++ ++ QQ
Sbjct: 598 EEKIREQEEM----MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 653
Query: 736 LEAIAKEHYERV 747
E + +EH E +
Sbjct: 654 EEKM-QEHQEHL 664
Score = 45.1 bits (105), Expect = 3e-04
Identities = 37/140 (26%), Positives = 70/140 (50%), Gaps = 3/140 (2%)
Query: 172 EDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLV 231
E + +E + ++Q++ R EM +Q ++ + EK E +++ + +K E +
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIRE 582
Query: 232 QEEKKRKALEAKKEEEEIQREMVKLRREIIER--RRTVKAAWKIEK-KRQEENSQNSSEK 288
Q+EK R+ E E+EE RE ++ +E E+ + K + EK + QEE + EK
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 289 VMFQSTHILPDEEKMVKERK 308
+ Q + EEKM + ++
Sbjct: 643 MWEQEVRLRQQEEKMQEHQE 662
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/164 (18%), Positives = 84/164 (51%), Gaps = 4/164 (2%)
Query: 176 RKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFL---EAQCLVQ 232
+ Q+K ++++ ++ + +E ++R ++E +++ EK ++ + E + Q
Sbjct: 483 KMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542
Query: 233 EEKKRKALEAKKEEEEIQREMVKLRREIIE-RRRTVKAAWKIEKKRQEENSQNSSEKVMF 291
EE ++ E E+EE +E K+RR+ + R + K + EK R++E E+ +
Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR 602
Query: 292 QSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHK 335
+ ++ ++E+ + E++ K+ E + ++ ++ +++ W +
Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/250 (22%), Positives = 98/250 (39%), Gaps = 21/250 (8%)
Query: 190 LTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEI 249
L M + + Q +L E R+ + K + LE +K+KA + EE+
Sbjct: 142 LQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA---DRYIEEL 198
Query: 250 QREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKR 309
+E L E+ T + + K QE+ SEK Q VKE KR
Sbjct: 199 TKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLN---------VKELKR 249
Query: 310 KLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRF 369
KL+ + ++ Q + + + + + L + Q + + WR +
Sbjct: 250 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI 309
Query: 370 QKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKR--ELALTKE 427
Q+ E + Q E +RE+ K + E R+Q E W E ++R E+ KE
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQ-------EEMMWEKEEKMRRQEEMMWEKE 362
Query: 428 ETRKKMDALL 437
E ++++ ++
Sbjct: 363 EKMRRLEEMM 372
Score = 40.4 bits (93), Expect = 0.008
Identities = 32/146 (21%), Positives = 73/146 (50%), Gaps = 10/146 (6%)
Query: 144 LEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENR 203
+ E+EE Q+ + + + + E +G +E + ++Q+K R ++R +E +
Sbjct: 525 IREQEEKIREQE--EKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE---QEEK 579
Query: 204 LRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIER 263
+R +KE ++ EK ++ + Q + +E++ K E +EE++ + K++ + +
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE---QEEKMCEQEEKMQEQEEKM 636
Query: 264 RRTVKAAW--KIEKKRQEENSQNSSE 287
RR + W ++ ++QEE Q E
Sbjct: 637 RRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 37.4 bits (85), Expect = 0.066
Identities = 37/168 (22%), Positives = 76/168 (45%), Gaps = 24/168 (14%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAA-EHALAVTEAQSHLLSKPREEEPRT 617
Q++ I +Q++K++EQ++ I E ++ +Q E + E + E K RE+E +
Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580
Query: 618 CQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAE 677
E + R + + +++ +++ EE+ ++ E E
Sbjct: 581 -------------REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELE 725
K ++QEE+ RQ+ + E+E +L R++EEK + + LE
Sbjct: 628 KMQEQEEKM---------RRQEEKMWEQEVRL-RQQEEKMQEHQEHLE 665
Score = 36.2 bits (82), Expect = 0.15
Identities = 45/272 (16%), Positives = 116/272 (42%), Gaps = 48/272 (17%)
Query: 662 EERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKM 721
E A+ R + +++ K++ KL +E+ Q E+E+ E QL K +++L++
Sbjct: 201 ERDALSLELYRNTITDEELKEKNAKL------QEKLQLVESEKSEIQLNVKELKRKLERA 254
Query: 722 KEL----------------------EKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR 759
K L + Q +++ N+ + ++ E++ +++ ++ W+
Sbjct: 255 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314
Query: 760 LRMQSKQNIQVAEE---HYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQ 816
+ ++ I+ EE ++R+ + W ++ ++ ++ ++ L+ ++
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMW-EKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 817 SWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGK----------HEIAAEH 866
+ + +L+E++ + Q+KI E KI Q K E
Sbjct: 374 EKEEKIRELEEKMHE------QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427
Query: 867 SDRRILWITLRTWKKFVKFMKEERVKEERRQQ 898
+ +I + W++ K ++E+++EE ++Q
Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 459
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 60.8 bits (146), Expect = 6e-09
Identities = 65/297 (21%), Positives = 141/297 (47%), Gaps = 33/297 (11%)
Query: 164 NVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQ--RIEKTLKK 221
N+++ E + R+E + ++Q+ + E++ ++ +E R+E+++ Q +I + K
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQE-EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 222 SAFLEAQCLVQEEKKRKALE---------------AKKEEEEIQREMVKLRREIIERRRT 266
E + QEEK R+ E +++EEE+ R+ K+R + E +R
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ--EEKRQ 405
Query: 267 VKAAWKIEKKRQEENSQ-NSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQC 325
K W+ EKK +E++ + E+ M++ + + E+M+++++ KL+EV + +E ++
Sbjct: 406 EK-MWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 326 QKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLRE 385
Q++ + + +I+ + T K+ + + W + + E + E ++E
Sbjct: 465 QEQEEKIQRQ---EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Query: 386 ENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASL 442
+ K Q E R+Q +R WQ E +E + +E +++ L Q A L
Sbjct: 522 QEEKMQRQEEKMREQEVR----LWQQ----EEKMQEQEVRLQELEERLGKLGQKAEL 570
Score = 53.9 bits (128), Expect = 7e-07
Identities = 50/274 (18%), Positives = 131/274 (47%), Gaps = 17/274 (6%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNL-QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRT 617
Q++ + +Q++K+QEQ++ + E + + + E W E + E K RE+E +
Sbjct: 295 QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE------EKIREQEDKM 348
Query: 618 CQMLVNSPVASPGTEGRSDSR-NSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILA 676
+ + + +R + +++ + EE+ ++ E R+
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM 408
Query: 677 EKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQL 736
+++K+ E+ +++ QEEE ++E + +E + + +E++L++++E +++ K +Q
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 737 EAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLA 796
E I ++ + ++++ + W++ ++ KQ ++ E+ ++ Q + M ++ QE
Sbjct: 469 EKIQRQEEK---IQEQEEKTWRQEKL-LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE 524
Query: 797 RKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVR 830
+ Q ++ Q ++ W Q ++EVR
Sbjct: 525 KMQRQEEKMREQ-----EVRLWQQEEKMQEQEVR 553
Score = 53.1 bits (126), Expect = 1e-06
Identities = 60/272 (22%), Positives = 114/272 (41%), Gaps = 35/272 (12%)
Query: 182 KKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALE 241
K++ + +L + + QV+ +RL +E + +++ ++++ QEEK +
Sbjct: 245 KRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWR--- 301
Query: 242 AKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEE 301
+EE+IQ + K+ + ++ R + W RQEE EK+ Q + EE
Sbjct: 302 ---QEEKIQEQEEKMCEQELKIREQEEKMW-----RQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 302 KMVKERKRKLKE----------------VLIQTFKENQQCQKRYFAAWHKLILDHRIKLG 345
K ++E++ K++E IQ +E Q+ + + +
Sbjct: 354 K-IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 346 KAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLR-------EENRKQQLATEYNR 398
K D KI+ + WR + ++LE Q E LR EE K Q E +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 399 KQVLRHCFTEWQHWHGAELLKRELALTKEETR 430
+Q + E + W +LLK+E + ++E +
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/293 (20%), Positives = 135/293 (46%), Gaps = 41/293 (13%)
Query: 634 RSDSRNSLSGLRRKPK--QLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLK 691
+S+ + ++ L+RK + QL+ P L+ +R + E + + A+ + + EE +L L
Sbjct: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL 291
Query: 692 AQEEERQKREAEEKEAQLERKREEKRLK-------------KMKELEKQKRIKRNQQLEA 738
Q++E + EEK + E K E+ LK KM E E++ R + ++
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 739 IAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLAR- 797
K + +R++ + W++ +Q+ ++ E+ ++ Q + + ++ QE + R
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 798 --KMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKID 855
KM + D + + ++ + W Q +E++R+ +++ + +REV+
Sbjct: 412 EKKMREQD----EKIREQEEEMWRQ-----EEKIREL------EEMMQDQEEKLREVEEK 456
Query: 856 SQGKHEIAAEHSDR------RILWITLRTWKKFVKFMKEERVKEERRQQLRRK 902
Q + E E ++ +I +TW++ +EE++ E+ + R++
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE 509
Score = 47.0 bits (110), Expect = 8e-05
Identities = 50/226 (22%), Positives = 106/226 (46%), Gaps = 17/226 (7%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
+Q+ + +Q+KK++EQ + I E + E W E + E + + +EE+ R
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQE------EEMWRQEEKIRELEE----MMQDQEEKLREV 453
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
+ + + R ++ + ++ +LK +E I E + E+
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQE-EKIQEQEEKTWRQEKLLK--QEEKIWEQEEKMWRQEE 510
Query: 679 KKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRI-KRNQQLE 737
K ++EEK+ Q + ++ +RQ+ + E+E +L ++ E+ + ++++ E ++R+ K Q+ E
Sbjct: 511 KMWEQEEKM-QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Query: 738 AIAKEHYERVLLRKKGLEP--WKRLRMQSKQNIQVAEEHYSLFLQR 781
+ E R L P L+ Q Q++Q ++HY LQ+
Sbjct: 570 LLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQ 615
Score = 42.7 bits (99), Expect = 0.002
Identities = 107/575 (18%), Positives = 224/575 (38%), Gaps = 89/575 (15%)
Query: 230 LVQEEKKRKALEAKKEEEEIQRE----MVKLRREIIERRRTVKAAWKIEKKRQEENSQNS 285
L Q+ K R K E+ I E + ++ + R+R W + +E
Sbjct: 39 LEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQ 98
Query: 286 SEKVMFQSTHILPDEEKM----VKERKRKLKEVLIQTFKENQQC--QKRYFAAWHKLILD 339
++ + + T LPD+E + V K+ EV +FK+ Q+ +K Y +I
Sbjct: 99 CKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVK-SSFKKRQEKMNEKNYTFRKRVVIKK 157
Query: 340 HRIKLG-----KAGTLSDWKIQLKVLRAWRDYTRFQKL--ERETQALE---NDLREENRK 389
++LG K S + L A R T +KL ER+ +LE N + +E K
Sbjct: 158 PWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK 217
Query: 390 QQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANG 449
++ A + +++ E K E+ L ++ ++K++
Sbjct: 218 EKNAELQEKLRLV-------------ESEKSEIQLNVKDLKRKLER-------------- 250
Query: 450 LSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQN 509
+ + LP++ + E LG +S L N +L N
Sbjct: 251 -AQLLLPQQQLQV-----------------EADRLGKELQSVSAKLQAQVEENELWNLLN 292
Query: 510 VSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKK 569
+Q + + + + +R +K + + Q++ I +Q+ K
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK-----MWRQEEKMHEQEEKIREQEDK 347
Query: 570 LQEQQKTILELKKNL-QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVAS 628
+ Q++ I E ++ + + E W E + Q + + EE R + +
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKI---REQDEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 629 PGTEGRSDS--RNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK------KK 680
R + R +R + +++ ++ +EE + E R + EK K
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 681 KQEEEKLAQLKAQ-EEERQKREAEEKEAQLERKREEKRLKKMKELEK--QKRIKRNQQLE 737
+++EEK+ + + + +E+ +K +EK + E K E+ K ++ EK ++ K +Q E
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE 524
Query: 738 AIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAE 772
+ ++ + +R++ + W++ +Q +++ E
Sbjct: 525 KMQRQEEK---MREQEVRLWQQEEKMQEQEVRLQE 556
Score = 30.4 bits (67), Expect = 8.1
Identities = 44/255 (17%), Positives = 118/255 (46%), Gaps = 47/255 (18%)
Query: 684 EEKLAQLKAQEEERQKR-EAEEKEAQLERKREEKRLKKMKELEKQKRI-----KRNQQLE 737
+E+L + A+ +E+ + E+E+ E QL K +++L++ + L Q+++ + ++L+
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272
Query: 738 AIAKEHYERV--------LLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQ 789
+++ + +V L +++ + W++ +Q ++ E+ + Q + M +
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332
Query: 790 RSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMV 849
+ E + Q D+ + Q + + + +E++R+ ++K++R
Sbjct: 333 KMHEQEEKIREQEDKMWRQ----------EEKIREQEEKIRE-----QEEKMWR------ 371
Query: 850 REVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVEILPD 909
+E KI Q D +I W++ K ++E ++E+ + +K+ E D
Sbjct: 372 QEEKIREQ----------DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE--QD 419
Query: 910 FQVPGRYHELYQQSD 924
++ + E+++Q +
Sbjct: 420 EKIREQEEEMWRQEE 434
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 60.8 bits (146), Expect = 6e-09
Identities = 65/297 (21%), Positives = 141/297 (47%), Gaps = 33/297 (11%)
Query: 164 NVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQ--RIEKTLKK 221
N+++ E + R+E + ++Q+ + E++ ++ +E R+E+++ Q +I + K
Sbjct: 289 NLLNQQQEEKMWRQEEKIQEQE-EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 222 SAFLEAQCLVQEEKKRKALE---------------AKKEEEEIQREMVKLRREIIERRRT 266
E + QEEK R+ E +++EEE+ R+ K+R + E +R
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ--EEKRQ 405
Query: 267 VKAAWKIEKKRQEENSQ-NSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQC 325
K W+ EKK +E++ + E+ M++ + + E+M+++++ KL+EV + +E ++
Sbjct: 406 EK-MWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 326 QKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLRE 385
Q++ + + +I+ + T K+ + + W + + E + E ++E
Sbjct: 465 QEQEEKIQRQ---EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Query: 386 ENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASL 442
+ K Q E R+Q +R WQ E +E + +E +++ L Q A L
Sbjct: 522 QEEKMQRQEEKMREQEVR----LWQQ----EEKMQEQEVRLQELEERLGKLGQKAEL 570
Score = 53.9 bits (128), Expect = 7e-07
Identities = 50/274 (18%), Positives = 131/274 (47%), Gaps = 17/274 (6%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNL-QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRT 617
Q++ + +Q++K+QEQ++ + E + + + E W E + E K RE+E +
Sbjct: 295 QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE------EKIREQEDKM 348
Query: 618 CQMLVNSPVASPGTEGRSDSR-NSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILA 676
+ + + +R + +++ + EE+ ++ E R+
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM 408
Query: 677 EKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQL 736
+++K+ E+ +++ QEEE ++E + +E + + +E++L++++E +++ K +Q
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 737 EAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLA 796
E I ++ + ++++ + W++ ++ KQ ++ E+ ++ Q + M ++ QE
Sbjct: 469 EKIQRQEEK---IQEQEEKTWRQEKL-LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE 524
Query: 797 RKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVR 830
+ Q ++ Q ++ W Q ++EVR
Sbjct: 525 KMQRQEEKMREQ-----EVRLWQQEEKMQEQEVR 553
Score = 53.1 bits (126), Expect = 1e-06
Identities = 60/272 (22%), Positives = 114/272 (41%), Gaps = 35/272 (12%)
Query: 182 KKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALE 241
K++ + +L + + QV+ +RL +E + +++ ++++ QEEK +
Sbjct: 245 KRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWR--- 301
Query: 242 AKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEE 301
+EE+IQ + K+ + ++ R + W RQEE EK+ Q + EE
Sbjct: 302 ---QEEKIQEQEEKMCEQELKIREQEEKMW-----RQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 302 KMVKERKRKLKE----------------VLIQTFKENQQCQKRYFAAWHKLILDHRIKLG 345
K ++E++ K++E IQ +E Q+ + + +
Sbjct: 354 K-IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 346 KAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLR-------EENRKQQLATEYNR 398
K D KI+ + WR + ++LE Q E LR EE K Q E +
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 399 KQVLRHCFTEWQHWHGAELLKRELALTKEETR 430
+Q + E + W +LLK+E + ++E +
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/293 (20%), Positives = 135/293 (46%), Gaps = 41/293 (13%)
Query: 634 RSDSRNSLSGLRRKPK--QLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLK 691
+S+ + ++ L+RK + QL+ P L+ +R + E + + A+ + + EE +L L
Sbjct: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGK--ELQSVSAKLQAQVEENELWNLL 291
Query: 692 AQEEERQKREAEEKEAQLERKREEKRLK-------------KMKELEKQKRIKRNQQLEA 738
Q++E + EEK + E K E+ LK KM E E++ R + ++
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 739 IAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLAR- 797
K + +R++ + W++ +Q+ ++ E+ ++ Q + + ++ QE + R
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQ 411
Query: 798 --KMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKID 855
KM + D + + ++ + W Q +E++R+ +++ + +REV+
Sbjct: 412 EKKMREQD----EKIREQEEEMWRQ-----EEKIREL------EEMMQDQEEKLREVEEK 456
Query: 856 SQGKHEIAAEHSDR------RILWITLRTWKKFVKFMKEERVKEERRQQLRRK 902
Q + E E ++ +I +TW++ +EE++ E+ + R++
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE 509
Score = 47.0 bits (110), Expect = 8e-05
Identities = 50/226 (22%), Positives = 106/226 (46%), Gaps = 17/226 (7%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
+Q+ + +Q+KK++EQ + I E + E W E + E + + +EE+ R
Sbjct: 404 RQEKMWRQEKKMREQDEKIREQE------EEMWRQEEKIRELEE----MMQDQEEKLREV 453
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
+ + + R ++ + ++ +LK +E I E + E+
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQE-EKIQEQEEKTWRQEKLLK--QEEKIWEQEEKMWRQEE 510
Query: 679 KKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRI-KRNQQLE 737
K ++EEK+ Q + ++ +RQ+ + E+E +L ++ E+ + ++++ E ++R+ K Q+ E
Sbjct: 511 KMWEQEEKM-QEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAE 569
Query: 738 AIAKEHYERVLLRKKGLEP--WKRLRMQSKQNIQVAEEHYSLFLQR 781
+ E R L P L+ Q Q++Q ++HY LQ+
Sbjct: 570 LLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQ 615
Score = 43.9 bits (102), Expect = 7e-04
Identities = 106/575 (18%), Positives = 222/575 (38%), Gaps = 89/575 (15%)
Query: 230 LVQEEKKRKALEAKKEEEEIQRE----MVKLRREIIERRRTVKAAWKIEKKRQEENSQNS 285
L Q+ K R K E+ I E + ++ + R+R W + +E
Sbjct: 39 LEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQ 98
Query: 286 SEKVMFQSTHILPDEEKM----VKERKRKLKEVLIQTFKENQQC--QKRYFAAWHKLILD 339
++ + + T LPD+E + V K+ EV +FK+ Q+ +K Y +I
Sbjct: 99 CKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVK-SSFKKRQEKMNEKNYTFRKRVVIKK 157
Query: 340 HRIKLG-----KAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALE-----NDLREENRK 389
++LG K S + L A R T +KL +E AL N + +E K
Sbjct: 158 PWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELK 217
Query: 390 QQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANG 449
++ A + +++ E K E+ L ++ ++K++
Sbjct: 218 EKNAELQEKLRLV-------------ESEKSEIQLNVKDLKRKLER-------------- 250
Query: 450 LSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQN 509
+ + LP++ + E LG +S L N +L N
Sbjct: 251 -AQLLLPQQQLQV-----------------EADRLGKELQSVSAKLQAQVEENELWNLLN 292
Query: 510 VSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKK 569
+Q + + + + +R +K + + Q++ I +Q+ K
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK-----MWRQEEKMHEQEEKIREQEDK 347
Query: 570 LQEQQKTILELKKNL-QLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVAS 628
+ Q++ I E ++ + + E W E + Q + + EE R + +
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKI---REQDEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 629 PGTEGRSDS--RNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK------KK 680
R + R +R + +++ ++ +EE + E R + EK K
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 681 KQEEEKLAQLKAQ-EEERQKREAEEKEAQLERKREEKRLKKMKELEK--QKRIKRNQQLE 737
+++EEK+ + + + +E+ +K +EK + E K E+ K ++ EK ++ K +Q E
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE 524
Query: 738 AIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAE 772
+ ++ + +R++ + W++ +Q +++ E
Sbjct: 525 KMQRQEEK---MREQEVRLWQQEEKMQEQEVRLQE 556
Score = 30.4 bits (67), Expect = 8.1
Identities = 44/255 (17%), Positives = 118/255 (46%), Gaps = 47/255 (18%)
Query: 684 EEKLAQLKAQEEERQKR-EAEEKEAQLERKREEKRLKKMKELEKQKRI-----KRNQQLE 737
+E+L + A+ +E+ + E+E+ E QL K +++L++ + L Q+++ + ++L+
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272
Query: 738 AIAKEHYERV--------LLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQ 789
+++ + +V L +++ + W++ +Q ++ E+ + Q + M +
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332
Query: 790 RSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMV 849
+ E + Q D+ + Q + + + +E++R+ ++K++R
Sbjct: 333 KMHEQEEKIREQEDKMWRQ----------EEKIREQEEKIRE-----QEEKMWR------ 371
Query: 850 REVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVEILPD 909
+E KI Q D +I W++ K ++E ++E+ + +K+ E D
Sbjct: 372 QEEKIREQ----------DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE--QD 419
Query: 910 FQVPGRYHELYQQSD 924
++ + E+++Q +
Sbjct: 420 EKIREQEEEMWRQEE 434
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 60.8 bits (146), Expect = 6e-09
Identities = 43/198 (21%), Positives = 101/198 (51%), Gaps = 8/198 (4%)
Query: 612 EEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAE- 670
EEE P + G S R L+++ K+ + ++E+ ++ E
Sbjct: 327 EEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEE 386
Query: 671 -CRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKR 729
R++LAE++K+ E++K + + +E++R++REA ++ + +R+RE++ ++++ELE++++
Sbjct: 387 YKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRK 446
Query: 730 IKRNQQLEAIAKEHYER--VLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTW 787
+ ++ K ER +R++ E + L + +Q +Q ++ L+ ++
Sbjct: 447 EEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQ----EQAMLLECRWREME 502
Query: 788 FQRSQESLARKMAQADQF 805
R E L R++ Q +
Sbjct: 503 EHRQAERLQRQLQQEQAY 520
Score = 52.4 bits (124), Expect = 2e-06
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 27/204 (13%)
Query: 648 PKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEA 707
P+Q P I+ E ++R + R+ E K++ E + QL +E+Q RE EE +
Sbjct: 334 PEQEGEPSSIVNVPGESTLRR-DFLRLQQENKERSEALRRQQLL---QEQQLREQEEYKR 389
Query: 708 QLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLR-----KKGLEPWKRLRM 762
QL +R+ KR+++ KE +++R++ Q+ E A+ ER R K+ LE +R R
Sbjct: 390 QLLAERQ-KRIEQQKE--QRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRK 446
Query: 763 QSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQIL------------ 810
+ ++ + EE + +++Y+ + Q L Q Q + +L
Sbjct: 447 EEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQ 506
Query: 811 ---LKRVIQSWLQYVIDLQEEVRK 831
L+R +Q Y++ LQ + R+
Sbjct: 507 AERLQRQLQQEQAYLLSLQHDHRR 530
Score = 46.6 bits (109), Expect = 1e-04
Identities = 42/170 (24%), Positives = 83/170 (48%), Gaps = 20/170 (11%)
Query: 149 ESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREK 208
EST + F+ A+ +E Q ++Q++ R + R K++++ + +R +
Sbjct: 349 ESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRR 408
Query: 209 ELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVK 268
E QR E+ EA+ + E++R+ E K+ EE++R R+E ERRR +
Sbjct: 409 LEEQQRRER--------EARRQQEREQRRREQEEKRRLEELERR----RKEEEERRRAEE 456
Query: 269 AAWKIEK-----KRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKE 313
++E+ +RQ E Q E + Q +L ++ +++ R R+++E
Sbjct: 457 EKRRVEREQEYIRRQLEEEQRHLEVLQQQ---LLQEQAMLLECRWREMEE 503
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/225 (18%), Positives = 96/225 (42%), Gaps = 13/225 (5%)
Query: 167 DSAMMEDLGRKENQDK--KQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAF 224
D E G +E +++ +Q+ +P + + + R ++ +R E ++
Sbjct: 317 DETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLL 376
Query: 225 LEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQN 284
E Q QEE KR+ L +++ E Q+E RR + E++R + A + +++ Q Q
Sbjct: 377 QEQQLREQEEYKRQLLAERQKRIEQQKEQ---RRRLEEQQRREREARRQQEREQRRREQE 433
Query: 285 SSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKL 344
++ +EE+ E +++ E + + + ++R+ + +L + L
Sbjct: 434 EKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAML 493
Query: 345 GKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRK 389
+ + + + R R Q+ ++ QA L+ ++R+
Sbjct: 494 --------LECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRR 530
Score = 34.3 bits (77), Expect = 0.56
Identities = 38/202 (18%), Positives = 87/202 (43%), Gaps = 20/202 (9%)
Query: 644 LRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAE 703
++R + + HP ++ R + + + +KK+ E+ + + E ++ E
Sbjct: 275 MQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVP 334
Query: 704 EKEAQ------------LERK--REEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLL 749
E+E + L R R ++ K+ E +++++ + QQL +E Y+R LL
Sbjct: 335 EQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLR--EQEEYKRQLL 392
Query: 750 RKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQI 809
E KR+ Q +Q ++ E+ R+ +R ++ R++ + ++ +
Sbjct: 393 ----AERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEE 448
Query: 810 LLKRVIQSWLQYVIDLQEEVRK 831
+R + + V QE +R+
Sbjct: 449 EERRRAEEEKRRVEREQEYIRR 470
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 60.5 bits (145), Expect = 7e-09
Identities = 49/257 (19%), Positives = 129/257 (50%), Gaps = 10/257 (3%)
Query: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKT--LKKSAFLEAQCLVQEE 234
+E ++K ++++ ++ + KE ++RR++E+ +++ EK L++ + + QEE
Sbjct: 305 QEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 364
Query: 235 KKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQST 294
K+++ + +++E+ ++E R+E R + K + E +++E E+ M++
Sbjct: 365 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQE 424
Query: 295 HILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLG-KAGTL--S 351
+ ++E+ ++ ++ K++E Q K +Q +K +++ + K+G + G +
Sbjct: 425 EEMQEQEEKMRRQEEKIRE---QEKKIREQEEK--IREQEEMMQEQEEKMGEQEGKMCEQ 479
Query: 352 DWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQH 411
+ K+Q + + R + ++ E++ + E +RE+ Q E +Q + C E +
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 539
Query: 412 WHGAELLKRELALTKEE 428
E ++R+ +E+
Sbjct: 540 QEQEEKMRRQEEKMREQ 556
Score = 53.9 bits (128), Expect = 7e-07
Identities = 82/418 (19%), Positives = 175/418 (41%), Gaps = 71/418 (16%)
Query: 521 KTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKK---KLQ------ 571
+ L A +Q+ ++ + +++ + L L + N + ++L EK K KLQ
Sbjct: 167 QALSAVATQKKKADRYIEELTKERDALSLELYRNT-ITDEELKEKNAKLQEKLQLVESEK 225
Query: 572 -EQQKTILELKKNLQLA-------EAQWAAEHALAVTEAQSHLLS------------KPR 611
E Q + ELK+ L+ A + Q A+H ++ S L +
Sbjct: 226 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 285
Query: 612 EEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAEC 671
+EE Q E R +RR+ + + ++ EE ++ E
Sbjct: 286 QEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 345
Query: 672 RRILAEKKKKQEEEKLAQLKAQEEE--RQKREAEEKEAQLERKRE-----EKRLKKMKEL 724
R L EK +QE+ + + K QEEE R++ + +E+EA++ R+ E E+++++ +E+
Sbjct: 346 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM 405
Query: 725 EKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYM 784
+++ K +Q E + ++ E +K +++R Q K ++ E+ + Q + M
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK---KIREQEEKIREQEEMM 462
Query: 785 LTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRA 844
++ E + Q + Q +E++R+ Q++ R
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQ-----------------EEKMRR------QEEKIRE 499
Query: 845 WFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRK 902
+RE + + + E+ E + + W++ K ++E +E+ +++RR+
Sbjct: 500 QEKKIREQEEKIREQEEMMQEQEE--------KMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Score = 51.2 bits (121), Expect = 4e-06
Identities = 55/267 (20%), Positives = 115/267 (43%), Gaps = 26/267 (9%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQ-WAAEHALAVTEAQSHLLSKPRE-EEPR 616
Q++ I +Q++K++ Q++ + E ++ ++ E W E + E + H K RE EE R
Sbjct: 307 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 366
Query: 617 TCQMLVNSPVASPGTEGR-----SDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAEC 671
+ + E + R +R + + + + EE+ ++ E
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 672 RRILAEKKKKQEEE--------KLAQLKAQEEERQKREAEEKEAQLERKREEKRLK---- 719
+ EK ++QEE+ + + K +E+E +E EEK + E K E+ K
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486
Query: 720 --KMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSL 777
KM+ E++ R + + E K + +++++ + W++ +Q ++ E+ +
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Query: 778 FLQRKYMLTWFQRSQESLARKMAQADQ 804
Q + M R QE R+ + Q
Sbjct: 547 RRQEEKM-----REQEVRLRQQEEKMQ 568
Score = 49.3 bits (116), Expect = 2e-05
Identities = 33/143 (23%), Positives = 80/143 (55%), Gaps = 7/143 (4%)
Query: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFL---EAQCLVQE 233
+E ++K ++++ ++ + + + +E ++R ++E+ ++ EK ++ + EA+ QE
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
Query: 234 EKKRKALEAKKEEEE-IQREMVKLRREIIERRRTVKAAWKIEKK--RQEENSQNSSEKVM 290
EK R+ E +E+E+ I+ + K+R + + + W+ E+K QEE Q EK+
Sbjct: 488 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547
Query: 291 FQSTHILPDEEKMVKERKRKLKE 313
Q + ++E +++++ K++E
Sbjct: 548 RQEEK-MREQEVRLRQQEEKMQE 569
Score = 47.0 bits (110), Expect = 8e-05
Identities = 42/261 (16%), Positives = 116/261 (44%), Gaps = 25/261 (9%)
Query: 76 KTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYD 135
+ E+I++ +E E +E + + + +QE E+ + + E +
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351
Query: 136 KFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMR 195
K + E+EE+ +K Q+K+Q+++ ++ +
Sbjct: 352 KMHEQEKIREQEEKRQEEEKI---------------------REQEKRQEQEAKMWRQEE 390
Query: 196 HKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVK 255
+ +E ++R ++E+ ++ EK ++ + Q +EE + + + +++EE+I+ + K
Sbjct: 391 KIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ---EEEMQEQEEKMRRQEEKIREQEKK 447
Query: 256 LRREIIERRRTVKAAWKIEKKR-QEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEV 314
+R + + R + + E+K ++E E M + + +E+ ++E+++K++E
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507
Query: 315 LIQTFKENQQCQKRYFAAWHK 335
+ ++ + Q++ W +
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQ 528
Score = 43.9 bits (102), Expect = 7e-04
Identities = 43/189 (22%), Positives = 86/189 (45%), Gaps = 17/189 (8%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNL-QLAEAQWAAEHALAVTEAQSHLLS-KPREEEPR 616
Q++ I +Q++K++EQ++ + E ++ + + E W E + E + K RE+E +
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Query: 617 TCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILA 676
+ + + + G + + M +E ++R E +
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE-------QEEKMRRQEEKIREQ 500
Query: 677 EKKKKQEEEKLAQLKA--QEEERQKREAEEKEAQLERKREEKRLK------KMKELEKQK 728
EKK +++EEK+ + + QE+E + E EEK + E K +E+ K KM+E E +
Sbjct: 501 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560
Query: 729 RIKRNQQLE 737
R + + E
Sbjct: 561 RQQEEKMQE 569
Score = 42.0 bits (97), Expect = 0.003
Identities = 55/278 (19%), Positives = 124/278 (44%), Gaps = 28/278 (10%)
Query: 148 EESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRRE 207
EE T + + L++N + +++ K + + + + +++ K++K R +
Sbjct: 184 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 243
Query: 208 KELEYQRIE-------KTLKK-SAFLEAQCLVQEEKKRKALEAKKEEEEI-QREMVKLRR 258
L Q+++ K L+ SA L+AQ V+E + L ++EE+ Q E ++ R
Sbjct: 244 LLLPQQQLQAEADHLGKELQSVSAKLQAQ--VEENELWNRLNQQQEEKMWRQEEKIQERE 301
Query: 259 EIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKL------- 311
E I+ + K + EK R++E E+ M + ++ ++E+ ++E + K+
Sbjct: 302 EKIQEQEE-KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360
Query: 312 ----KEVLIQTFKENQQCQKRYFAAW--HKLILDHRIKLGKAGTL---SDWKIQLKVLRA 362
K + +E ++ Q++ W + I + K+ + + + K+ + +
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 363 WRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQ 400
W Q+ E + + E +RE+ +K + E R+Q
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Score = 39.7 bits (91), Expect = 0.013
Identities = 38/196 (19%), Positives = 87/196 (44%), Gaps = 23/196 (11%)
Query: 69 WGQITDLKTSEQ-IEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPE 127
W Q ++ E+ I + +E+ E +E + + + +QE +E+ + E
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE 445
Query: 128 ANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKD 187
+ +K + ++E+EE Q + M E + + Q++K ++
Sbjct: 446 KKIREQEEKIREQEEMMQEQEEKMGEQ------------EGKMCEQEAKMQEQEEKMRRQ 493
Query: 188 PRLTMEMRHK-QVKENRLRREKELEYQRIEKTLKKSAFL---EAQCLVQEEKKRKALEAK 243
E K + +E ++R ++E+ ++ EK ++ + E + QEEK R
Sbjct: 494 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR------ 547
Query: 244 KEEEEIQREMVKLRRE 259
++EE+++ + V+LR++
Sbjct: 548 RQEEKMREQEVRLRQQ 563
Score = 33.9 bits (76), Expect = 0.73
Identities = 23/108 (21%), Positives = 55/108 (50%), Gaps = 3/108 (2%)
Query: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKEL---EYQRIEKTLKKSAFLEAQCLVQE 233
+E ++K +++ ++ + Q +E ++RR++E + ++I + +K E QE
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 522
Query: 234 EKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEEN 281
EK + E E+EE +E + R E+ R + + ++++ +E+
Sbjct: 523 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 33.1 bits (74), Expect = 1.2
Identities = 30/128 (23%), Positives = 60/128 (46%), Gaps = 18/128 (14%)
Query: 176 RKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEK 235
++E ++++K E K ++ +E+E + +R E+ +++ E + QEEK
Sbjct: 458 QEEMMQEQEEK----MGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ---EKKIREQEEK 510
Query: 236 KRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTH 295
R+ E +E+EE +M + ++ E+ + + QEE + EK+ Q
Sbjct: 511 IREQEEMMQEQEE---KMWEQEEKMCEQEE--------KMQEQEEKMRRQEEKMREQEVR 559
Query: 296 ILPDEEKM 303
+ EEKM
Sbjct: 560 LRQQEEKM 567
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 60.1 bits (144), Expect = 9e-09
Identities = 62/250 (24%), Positives = 105/250 (42%), Gaps = 21/250 (8%)
Query: 559 QQQLIEKQKKKLQE----QQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEE 614
Q + +EK+KK+LQE Q+K I ++ +L E L + EE
Sbjct: 673 QVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEER 732
Query: 615 PRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRI 674
T Q+ + R L +R K + LK EER + R+
Sbjct: 733 ITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERH-NRL 791
Query: 675 LAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKEL-EKQKRIKRN 733
K++++EE ++ + +EEE Q+R E+ + E + +R K+ +EL E Q+R+K+
Sbjct: 792 EERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKL 851
Query: 734 QQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQE 793
+++E ++ + R++ E +RL S L RK W R E
Sbjct: 852 EEVERKKRQRELEIEERERRREEERRLGDSS--------------LSRKDS-RWGDRDSE 896
Query: 794 SLARKMAQAD 803
RK +AD
Sbjct: 897 GTWRKGPEAD 906
Score = 57.0 bits (136), Expect = 8e-08
Identities = 70/333 (21%), Positives = 149/333 (44%), Gaps = 35/333 (10%)
Query: 588 EAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRK 647
+ Q +H S L RE+ P + + S +E + ++S + K
Sbjct: 479 DLQVRIDHTSRTLSFGSDLNYATREDAP------IGPHLQSMPSEQIRNQLTAMSSVLAK 532
Query: 648 PKQLMTPHPILKAMEER---------AIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQ 698
+++ P IL+ EE+ R E +RILA +++ EE+ +L++ +R+
Sbjct: 533 ALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILA--RRQTIEERKERLESLNIQRE 590
Query: 699 KREAEEKEAQLE--RKREEKRLK-KMKELEKQKRIKRNQQL-EAIAKEHYERVLLRKKGL 754
K E E++EA+L+ RK EE+RL+ + KE EK++ ++ ++Q+ + +E E++ + G
Sbjct: 591 KEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGA 650
Query: 755 EPWKRLRMQSKQNIQ---VAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILL 811
+ +K + ++ + + + + + K L ++QE +A + L+
Sbjct: 651 KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLI 710
Query: 812 KRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRI 871
K + +DL E+ + + +Q + RE ++ + + E D +
Sbjct: 711 KSAYEEQRIKDMDLWEQQEEERITTMQ---------LEREKALEHKNRMSRMLEDRDLFV 761
Query: 872 LWITLRTWKKFVKFMK--EERVKEERRQQLRRK 902
+ + + + +K EER+ EER +L +
Sbjct: 762 MRLKAARQSVYEEKLKQFEERLAEERHNRLEER 794
Score = 50.1 bits (118), Expect = 1e-05
Identities = 48/157 (30%), Positives = 81/157 (51%), Gaps = 18/157 (11%)
Query: 145 EEEEESTTVQKFIDHLL-HKNVVDSAMMEDLG----------RKENQDKKQQKDPRLTME 193
+EEE TT+Q + L HKN + S M+ED + ++K +Q + RL E
Sbjct: 728 QEEERITTMQLEREKALEHKNRM-SRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEE 786
Query: 194 MRHKQVKENRLRREKE--LEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEE--EI 249
RH +++E + +R++E + Y R EK ++ E Q L + E++ +A AK+EEE E
Sbjct: 787 -RHNRLEERKRQRKEERRITYYR-EKEEEEQRRAEEQMLKEREERERAERAKREEELREY 844
Query: 250 QREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSS 286
Q + KL ++R+ + E++R+EE S
Sbjct: 845 QERVKKLEEVERKKRQRELEIEERERRREEERRLGDS 881
Score = 49.3 bits (116), Expect = 2e-05
Identities = 74/289 (25%), Positives = 131/289 (45%), Gaps = 36/289 (12%)
Query: 178 ENQDKKQQK--DPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEK 235
+N K+ Q+ R T+E R ++++ ++REKE E ++ E L+K E + L QE K
Sbjct: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKE-ELEQREAELQKVRKAEEERLRQEAK 617
Query: 236 KRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWK-IEKKRQEE--------NSQNSS 286
+R+ +E E+I+++ V+ R E I++ A+K I+ + EE
Sbjct: 618 EREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQL 677
Query: 287 EKVMFQSTHILPDEEKMVK--ERKRKLKEV-LIQTFKENQQCQKRYFAAW---------- 333
EK + L ++EK + ER ++L+E+ LI++ E Q+ + W
Sbjct: 678 EKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKD--MDLWEQQEEERITT 735
Query: 334 ----HKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLER--ETQALENDLREEN 387
+ L+H+ ++ + L D + + L+A R +KL++ E A E R E
Sbjct: 736 MQLEREKALEHKNRMSR--MLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEE 793
Query: 388 RKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDAL 436
RK+Q E R R E Q ++LK + E K+ + L
Sbjct: 794 RKRQ-RKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEEL 841
Score = 37.0 bits (84), Expect = 0.086
Identities = 36/174 (20%), Positives = 84/174 (48%), Gaps = 11/174 (6%)
Query: 161 LHKNVVDSAMMEDLGRKENQDKKQQKDPRLTME--MRHKQVKENRLRREKELEYQRIEKT 218
L K+ + ++D+ E Q++++ +L E + HK + +R+ +++L R+ K
Sbjct: 709 LIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKN-RMSRMLEDRDLFVMRL-KA 766
Query: 219 LKKSAFLEA----QCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIE 274
++S + E + + EE+ + E K++ +E +R +E E+RR + K
Sbjct: 767 ARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826
Query: 275 KKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKR 328
++R+ E++ + EE ERK++ +E+ I+ + ++ ++R
Sbjct: 827 EERERAERAKREEELREYQERVKKLEE---VERKKRQRELEIEERERRREEERR 877
Score = 34.7 bits (78), Expect = 0.43
Identities = 37/163 (22%), Positives = 82/163 (50%), Gaps = 19/163 (11%)
Query: 232 QEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQE-ENSQNSSEKVM 290
+EE+ + A+ A + + + + RR+ IE R+ + I+++++E E + +KV
Sbjct: 546 KEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVR 605
Query: 291 FQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTL 350
+EE++ +E K + KE ++Q E++Q +K+ +L +IK + G
Sbjct: 606 ------KAEEERLRQEAKEREKERILQ---EHEQIKKK--TVRERL---EQIKKTELGAK 651
Query: 351 SDWKIQLKVLRAW-RDY---TRFQKLERETQALENDLREENRK 389
+ I ++ L D+ + ++LE+E + L+ L+ + +K
Sbjct: 652 AFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKK 694
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 60.1 bits (144), Expect = 9e-09
Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 34/239 (14%)
Query: 169 AMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQ 228
A E+ RK ++ ++Q++ L R +Q +E + R E+EL ++ E+ L++ E
Sbjct: 742 AKREEEERKRQEELRRQQEEIL----RRQQEEERKRREEEELARRKQEEALRRQREQEIA 797
Query: 229 CLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKK-----RQEENSQ 283
Q E+ E ++++EE R + + RRE ERR+ + K E++ R+EE +Q
Sbjct: 798 LRRQREE-----EERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 852
Query: 284 NSSEKVMFQSTHILPDEEKMVK----ERKRKLKEVLIQTFKE---NQQCQKRYFAAWHKL 336
E+ + L EE+ + E +RK KE+ +Q KE +Q Q+ +
Sbjct: 853 RRLEE------NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 906
Query: 337 ILDHRIKLGKAGTLSDWKIQLKVL----RAWRDYTRFQKLERETQALENDLREENRKQQ 391
++ K + S W Q +A QKLE E E LREE R+QQ
Sbjct: 907 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER---ERQLREEQRRQQ 962
Score = 57.0 bits (136), Expect = 8e-08
Identities = 64/247 (25%), Positives = 114/247 (46%), Gaps = 34/247 (13%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
Q Q +EK K EQ++ E++ + E + E + Q +L + +EEE +
Sbjct: 719 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE----LRRQQEEILRRQQEEERKRR 774
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
+ E R LRR+ +Q + + EE Q+ E R L E+
Sbjct: 775 E------------EEELARRKQEEALRRQREQEIALRR--QREEEERQQQEEALRRLEER 820
Query: 679 KKKQEEEKLAQ--LKAQEEERQKREAEEKEAQLERKREEKRLKKMKE---LEKQKRIKRN 733
++++EE + + L+ QEEE K EE+EAQ R+ EE RL+ +E L ++ ++
Sbjct: 821 RREEEERRKQEELLRKQEEEAAKWAREEEEAQ--RRLEENRLRMEEEAARLRHEEEERKR 878
Query: 734 QQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQE 793
++LE + E + R++ E +RL+ Q +Q Q+A+ ++ TW Q+S
Sbjct: 879 KELE--VQRQKELMRQRQQQQEALRRLQQQQQQQ-QLAQ------MKLPSSSTWGQQSNT 929
Query: 794 SLARKMA 800
+ + A
Sbjct: 930 TACQSQA 936
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/288 (25%), Positives = 113/288 (39%), Gaps = 47/288 (16%)
Query: 524 GAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHV-FQQQLIEKQKKK-LQEQQKTILELK 581
G P G + R T Q+ + +H+ +QQ LI++Q + L +QQK L +
Sbjct: 589 GPAPPPHMGELDQERLTRQQE---LTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQ 645
Query: 582 KNLQLAEAQWAAEHALAVTEAQSHLLSKPREEE-PRTCQMLVNSPVASPGTEGRSDSRNS 640
+ QLA + Q+ + S R P T + P AS T S
Sbjct: 646 QQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWD 705
Query: 641 LSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR 700
L P TP P L+ +++ E+ K A+L
Sbjct: 706 L------PLDTTTPGPALEQLQQL------------------EKAKAAKL---------- 731
Query: 701 EAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR- 759
E E +EA++ KREE+ K+ +EL +Q+ +Q E K E L R+K E +R
Sbjct: 732 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ 791
Query: 760 ------LRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQ 801
LR Q ++ + +E L+ + +R QE L RK +
Sbjct: 792 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 839
Score = 46.6 bits (109), Expect = 1e-04
Identities = 73/391 (18%), Positives = 151/391 (38%), Gaps = 37/391 (9%)
Query: 380 ENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQA 439
E D R+Q+L Y + + F Q + +++ AL+ ++ ++++ LLQ
Sbjct: 598 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQ-QQQLALLLQQ 656
Query: 440 ASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTT 499
K+ +S ++ T V P G + P +P + G + PL TT
Sbjct: 657 FQTLKMR---ISDQNIIPSVTRSVSVP-DTGSIWELQPTASQPTVWEGGSVWDLPLDTTT 712
Query: 500 TGNLQGSLQNVSLSAPGNKQHKTLGAE-----PSQQPGSNETLRTTSQKAEPLCLGHFHN 554
G LQ + + + + AE ++ E LR ++
Sbjct: 713 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 772
Query: 555 RHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEA---------QSH 605
R ++ KQ++ L+ Q++ + L++ + E Q E + E Q
Sbjct: 773 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
Query: 606 LLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERA 665
LL K EE + + E R + LR + ++ ++ +E
Sbjct: 833 LLRKQEEEAAKWARE--EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM 890
Query: 666 IQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR----------------EAEEKEAQL 709
QR + + L +++Q++++LAQ+K + E ++ E +
Sbjct: 891 RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 950
Query: 710 ERKREEKRLKKMKELEKQKRIKRNQQLEAIA 740
ER+ E++ ++ +EL K + ++ QQ + ++
Sbjct: 951 ERQLREEQRRQQRELMKALQQQQQQQQQKLS 981
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 60.1 bits (144), Expect = 9e-09
Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 34/239 (14%)
Query: 169 AMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQ 228
A E+ RK ++ ++Q++ L R +Q +E + R E+EL ++ E+ L++ E
Sbjct: 769 AKREEEERKRQEELRRQQEEIL----RRQQEEERKRREEEELARRKQEEALRRQREQEIA 824
Query: 229 CLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKK-----RQEENSQ 283
Q E+ E ++++EE R + + RRE ERR+ + K E++ R+EE +Q
Sbjct: 825 LRRQREE-----EERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 879
Query: 284 NSSEKVMFQSTHILPDEEKMVK----ERKRKLKEVLIQTFKE---NQQCQKRYFAAWHKL 336
E+ + L EE+ + E +RK KE+ +Q KE +Q Q+ +
Sbjct: 880 RRLEE------NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 933
Query: 337 ILDHRIKLGKAGTLSDWKIQLKVL----RAWRDYTRFQKLERETQALENDLREENRKQQ 391
++ K + S W Q +A QKLE E E LREE R+QQ
Sbjct: 934 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER---ERQLREEQRRQQ 989
Score = 57.0 bits (136), Expect = 8e-08
Identities = 64/247 (25%), Positives = 114/247 (46%), Gaps = 34/247 (13%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
Q Q +EK K EQ++ E++ + E + E + Q +L + +EEE +
Sbjct: 746 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE----LRRQQEEILRRQQEEERKRR 801
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
+ E R LRR+ +Q + + EE Q+ E R L E+
Sbjct: 802 E------------EEELARRKQEEALRRQREQEIALRR--QREEEERQQQEEALRRLEER 847
Query: 679 KKKQEEEKLAQ--LKAQEEERQKREAEEKEAQLERKREEKRLKKMKE---LEKQKRIKRN 733
++++EE + + L+ QEEE K EE+EAQ R+ EE RL+ +E L ++ ++
Sbjct: 848 RREEEERRKQEELLRKQEEEAAKWAREEEEAQ--RRLEENRLRMEEEAARLRHEEEERKR 905
Query: 734 QQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQE 793
++LE + E + R++ E +RL+ Q +Q Q+A+ ++ TW Q+S
Sbjct: 906 KELE--VQRQKELMRQRQQQQEALRRLQQQQQQQ-QLAQ------MKLPSSSTWGQQSNT 956
Query: 794 SLARKMA 800
+ + A
Sbjct: 957 TACQSQA 963
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/288 (25%), Positives = 113/288 (39%), Gaps = 47/288 (16%)
Query: 524 GAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHV-FQQQLIEKQKKK-LQEQQKTILELK 581
G P G + R T Q+ + +H+ +QQ LI++Q + L +QQK L +
Sbjct: 616 GPAPPPHMGELDQERLTRQQE---LTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQ 672
Query: 582 KNLQLAEAQWAAEHALAVTEAQSHLLSKPREEE-PRTCQMLVNSPVASPGTEGRSDSRNS 640
+ QLA + Q+ + S R P T + P AS T S
Sbjct: 673 QQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWD 732
Query: 641 LSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR 700
L P TP P L+ +++ E+ K A+L
Sbjct: 733 L------PLDTTTPGPALEQLQQL------------------EKAKAAKL---------- 758
Query: 701 EAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR- 759
E E +EA++ KREE+ K+ +EL +Q+ +Q E K E L R+K E +R
Sbjct: 759 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ 818
Query: 760 ------LRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQ 801
LR Q ++ + +E L+ + +R QE L RK +
Sbjct: 819 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 866
Score = 46.6 bits (109), Expect = 1e-04
Identities = 73/391 (18%), Positives = 151/391 (38%), Gaps = 37/391 (9%)
Query: 380 ENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQA 439
E D R+Q+L Y + + F Q + +++ AL+ ++ ++++ LLQ
Sbjct: 625 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQ-QQQLALLLQQ 683
Query: 440 ASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTT 499
K+ +S ++ T V P G + P +P + G + PL TT
Sbjct: 684 FQTLKMR---ISDQNIIPSVTRSVSVP-DTGSIWELQPTASQPTVWEGGSVWDLPLDTTT 739
Query: 500 TGNLQGSLQNVSLSAPGNKQHKTLGAE-----PSQQPGSNETLRTTSQKAEPLCLGHFHN 554
G LQ + + + + AE ++ E LR ++
Sbjct: 740 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 799
Query: 555 RHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEA---------QSH 605
R ++ KQ++ L+ Q++ + L++ + E Q E + E Q
Sbjct: 800 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
Query: 606 LLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERA 665
LL K EE + + E R + LR + ++ ++ +E
Sbjct: 860 LLRKQEEEAAKWARE--EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM 917
Query: 666 IQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR----------------EAEEKEAQL 709
QR + + L +++Q++++LAQ+K + E ++ E +
Sbjct: 918 RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 977
Query: 710 ERKREEKRLKKMKELEKQKRIKRNQQLEAIA 740
ER+ E++ ++ +EL K + ++ QQ + ++
Sbjct: 978 ERQLREEQRRQQRELMKALQQQQQQQQQKLS 1008
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 60.1 bits (144), Expect = 9e-09
Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 34/239 (14%)
Query: 169 AMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQ 228
A E+ RK ++ ++Q++ L R +Q +E + R E+EL ++ E+ L++ E
Sbjct: 748 AKREEEERKRQEELRRQQEEIL----RRQQEEERKRREEEELARRKQEEALRRQREQEIA 803
Query: 229 CLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKK-----RQEENSQ 283
Q E+ E ++++EE R + + RRE ERR+ + K E++ R+EE +Q
Sbjct: 804 LRRQREE-----EERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 858
Query: 284 NSSEKVMFQSTHILPDEEKMVK----ERKRKLKEVLIQTFKE---NQQCQKRYFAAWHKL 336
E+ + L EE+ + E +RK KE+ +Q KE +Q Q+ +
Sbjct: 859 RRLEE------NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
Query: 337 ILDHRIKLGKAGTLSDWKIQLKVL----RAWRDYTRFQKLERETQALENDLREENRKQQ 391
++ K + S W Q +A QKLE E E LREE R+QQ
Sbjct: 913 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER---ERQLREEQRRQQ 968
Score = 57.0 bits (136), Expect = 8e-08
Identities = 64/247 (25%), Positives = 114/247 (46%), Gaps = 34/247 (13%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
Q Q +EK K EQ++ E++ + E + E + Q +L + +EEE +
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE----LRRQQEEILRRQQEEERKRR 780
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
+ E R LRR+ +Q + + EE Q+ E R L E+
Sbjct: 781 E------------EEELARRKQEEALRRQREQEIALRR--QREEEERQQQEEALRRLEER 826
Query: 679 KKKQEEEKLAQ--LKAQEEERQKREAEEKEAQLERKREEKRLKKMKE---LEKQKRIKRN 733
++++EE + + L+ QEEE K EE+EAQ R+ EE RL+ +E L ++ ++
Sbjct: 827 RREEEERRKQEELLRKQEEEAAKWAREEEEAQ--RRLEENRLRMEEEAARLRHEEEERKR 884
Query: 734 QQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQE 793
++LE + E + R++ E +RL+ Q +Q Q+A+ ++ TW Q+S
Sbjct: 885 KELE--VQRQKELMRQRQQQQEALRRLQQQQQQQ-QLAQ------MKLPSSSTWGQQSNT 935
Query: 794 SLARKMA 800
+ + A
Sbjct: 936 TACQSQA 942
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/288 (25%), Positives = 113/288 (39%), Gaps = 47/288 (16%)
Query: 524 GAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHV-FQQQLIEKQKKK-LQEQQKTILELK 581
G P G + R T Q+ + +H+ +QQ LI++Q + L +QQK L +
Sbjct: 595 GPAPPPHMGELDQERLTRQQE---LTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQ 651
Query: 582 KNLQLAEAQWAAEHALAVTEAQSHLLSKPREEE-PRTCQMLVNSPVASPGTEGRSDSRNS 640
+ QLA + Q+ + S R P T + P AS T S
Sbjct: 652 QQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWD 711
Query: 641 LSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR 700
L P TP P L+ +++ E+ K A+L
Sbjct: 712 L------PLDTTTPGPALEQLQQL------------------EKAKAAKL---------- 737
Query: 701 EAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR- 759
E E +EA++ KREE+ K+ +EL +Q+ +Q E K E L R+K E +R
Sbjct: 738 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ 797
Query: 760 ------LRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQ 801
LR Q ++ + +E L+ + +R QE L RK +
Sbjct: 798 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845
Score = 46.6 bits (109), Expect = 1e-04
Identities = 73/391 (18%), Positives = 151/391 (38%), Gaps = 37/391 (9%)
Query: 380 ENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQA 439
E D R+Q+L Y + + F Q + +++ AL+ ++ ++++ LLQ
Sbjct: 604 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQ-QQQLALLLQQ 662
Query: 440 ASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTT 499
K+ +S ++ T V P G + P +P + G + PL TT
Sbjct: 663 FQTLKMR---ISDQNIIPSVTRSVSVP-DTGSIWELQPTASQPTVWEGGSVWDLPLDTTT 718
Query: 500 TGNLQGSLQNVSLSAPGNKQHKTLGAE-----PSQQPGSNETLRTTSQKAEPLCLGHFHN 554
G LQ + + + + AE ++ E LR ++
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778
Query: 555 RHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEA---------QSH 605
R ++ KQ++ L+ Q++ + L++ + E Q E + E Q
Sbjct: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
Query: 606 LLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERA 665
LL K EE + + E R + LR + ++ ++ +E
Sbjct: 839 LLRKQEEEAAKWARE--EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM 896
Query: 666 IQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR----------------EAEEKEAQL 709
QR + + L +++Q++++LAQ+K + E ++ E +
Sbjct: 897 RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 956
Query: 710 ERKREEKRLKKMKELEKQKRIKRNQQLEAIA 740
ER+ E++ ++ +EL K + ++ QQ + ++
Sbjct: 957 ERQLREEQRRQQRELMKALQQQQQQQQQKLS 987
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 60.1 bits (144), Expect = 9e-09
Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 34/239 (14%)
Query: 169 AMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQ 228
A E+ RK ++ ++Q++ L R +Q +E + R E+EL ++ E+ L++ E
Sbjct: 748 AKREEEERKRQEELRRQQEEIL----RRQQEEERKRREEEELARRKQEEALRRQREQEIA 803
Query: 229 CLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKK-----RQEENSQ 283
Q E+ E ++++EE R + + RRE ERR+ + K E++ R+EE +Q
Sbjct: 804 LRRQREE-----EERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQ 858
Query: 284 NSSEKVMFQSTHILPDEEKMVK----ERKRKLKEVLIQTFKE---NQQCQKRYFAAWHKL 336
E+ + L EE+ + E +RK KE+ +Q KE +Q Q+ +
Sbjct: 859 RRLEE------NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
Query: 337 ILDHRIKLGKAGTLSDWKIQLKVL----RAWRDYTRFQKLERETQALENDLREENRKQQ 391
++ K + S W Q +A QKLE E E LREE R+QQ
Sbjct: 913 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER---ERQLREEQRRQQ 968
Score = 57.0 bits (136), Expect = 8e-08
Identities = 64/247 (25%), Positives = 114/247 (46%), Gaps = 34/247 (13%)
Query: 559 QQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTC 618
Q Q +EK K EQ++ E++ + E + E + Q +L + +EEE +
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE----LRRQQEEILRRQQEEERKRR 780
Query: 619 QMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEK 678
+ E R LRR+ +Q + + EE Q+ E R L E+
Sbjct: 781 E------------EEELARRKQEEALRRQREQEIALRR--QREEEERQQQEEALRRLEER 826
Query: 679 KKKQEEEKLAQ--LKAQEEERQKREAEEKEAQLERKREEKRLKKMKE---LEKQKRIKRN 733
++++EE + + L+ QEEE K EE+EAQ R+ EE RL+ +E L ++ ++
Sbjct: 827 RREEEERRKQEELLRKQEEEAAKWAREEEEAQ--RRLEENRLRMEEEAARLRHEEEERKR 884
Query: 734 QQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQE 793
++LE + E + R++ E +RL+ Q +Q Q+A+ ++ TW Q+S
Sbjct: 885 KELE--VQRQKELMRQRQQQQEALRRLQQQQQQQ-QLAQ------MKLPSSSTWGQQSNT 935
Query: 794 SLARKMA 800
+ + A
Sbjct: 936 TACQSQA 942
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/288 (25%), Positives = 113/288 (39%), Gaps = 47/288 (16%)
Query: 524 GAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHV-FQQQLIEKQKKK-LQEQQKTILELK 581
G P G + R T Q+ + +H+ +QQ LI++Q + L +QQK L +
Sbjct: 595 GPAPPPHMGELDQERLTRQQE---LTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQ 651
Query: 582 KNLQLAEAQWAAEHALAVTEAQSHLLSKPREEE-PRTCQMLVNSPVASPGTEGRSDSRNS 640
+ QLA + Q+ + S R P T + P AS T S
Sbjct: 652 QQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWD 711
Query: 641 LSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR 700
L P TP P L+ +++ E+ K A+L
Sbjct: 712 L------PLDTTTPGPALEQLQQL------------------EKAKAAKL---------- 737
Query: 701 EAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR- 759
E E +EA++ KREE+ K+ +EL +Q+ +Q E K E L R+K E +R
Sbjct: 738 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ 797
Query: 760 ------LRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQ 801
LR Q ++ + +E L+ + +R QE L RK +
Sbjct: 798 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845
Score = 46.6 bits (109), Expect = 1e-04
Identities = 73/391 (18%), Positives = 151/391 (38%), Gaps = 37/391 (9%)
Query: 380 ENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQA 439
E D R+Q+L Y + + F Q + +++ AL+ ++ ++++ LLQ
Sbjct: 604 ELDQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQ-QQQLALLLQQ 662
Query: 440 ASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTT 499
K+ +S ++ T V P G + P +P + G + PL TT
Sbjct: 663 FQTLKMR---ISDQNIIPSVTRSVSVP-DTGSIWELQPTASQPTVWEGGSVWDLPLDTTT 718
Query: 500 TGNLQGSLQNVSLSAPGNKQHKTLGAE-----PSQQPGSNETLRTTSQKAEPLCLGHFHN 554
G LQ + + + + AE ++ E LR ++
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK 778
Query: 555 RHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEA---------QSH 605
R ++ KQ++ L+ Q++ + L++ + E Q E + E Q
Sbjct: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
Query: 606 LLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERA 665
LL K EE + + E R + LR + ++ ++ +E
Sbjct: 839 LLRKQEEEAAKWARE--EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELM 896
Query: 666 IQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR----------------EAEEKEAQL 709
QR + + L +++Q++++LAQ+K + E ++ E +
Sbjct: 897 RQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER 956
Query: 710 ERKREEKRLKKMKELEKQKRIKRNQQLEAIA 740
ER+ E++ ++ +EL K + ++ QQ + ++
Sbjct: 957 ERQLREEQRRQQRELMKALQQQQQQQQQKLS 987
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 60.1 bits (144), Expect = 9e-09
Identities = 133/630 (21%), Positives = 264/630 (41%), Gaps = 121/630 (19%)
Query: 143 YLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKEN 202
YL E+++ ++ I L DS ++ + QD +QQ+ +E+R ++ +
Sbjct: 718 YLSLEQKTEELEGQIKKL----EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSK- 772
Query: 203 RLRREKELEYQRIEKTLKKSAFLEA--QCLVQEEKKRKAL---------EAKKEEEE--- 248
+L EKE+ KKS LE+ Q L ++E++++ L E K + EE
Sbjct: 773 QLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN 832
Query: 249 -IQREMVKLRREIIERRRTVKAAWKIEKKRQE-----ENSQNSSEKVMFQSTHILPDEEK 302
IQ + +L++ +E+ + ++ K + +NS++ EK + + D EK
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEK 892
Query: 303 MVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRA 362
KE K +L+ + T KE ++ +K + + H++KL +Q ++++A
Sbjct: 893 TCKELKHQLQVQMENTLKEQKELKK---SLEKEKEASHQLKLELNS------MQEQLIQA 943
Query: 363 WRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKREL 422
+ +K E++ Q N+L++ ++E +KQ+ E L+ EL
Sbjct: 944 QNTLKQNEKEEQQLQGNINELKQ-------SSEQKKKQI--------------EALQGEL 982
Query: 423 ---ALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLW 479
L K E K+ L A+ ++ +E +++ + QET
Sbjct: 983 KIAVLQKTELENKLQQQLTQAA---------QELAAEKEKISVLQNNYEKSQETFKQ--L 1031
Query: 480 EKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRT 539
+ G +L+ T +L+ + +SL+ + L + +Q N+ ++
Sbjct: 1032 QSDFYGRESELLA------TRQDLKSVEEKLSLA------QEDLISNRNQIGNQNKLIQE 1079
Query: 540 TSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAV 599
L +Q K++++LQE+ K + +++K L E + E
Sbjct: 1080 LKTAKATL------------EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEK---- 1123
Query: 600 TEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLR--RKPKQLMTPHPI 657
SK E E C+ + E +S S+ + + KQL+ I
Sbjct: 1124 --------SKLAEIEEIKCRQ--EKEITKLNEELKSHKLESIKEITNLKDAKQLL----I 1169
Query: 658 LKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKR 717
+ +E + +A+ + E++K+ ++ Q+K +EEE K+E EKEA+L + +EK
Sbjct: 1170 QQKLELQG--KADSLKAAVEQEKRNQQILKDQVKKEEEEL-KKEFIEKEAKLHSEIKEKE 1226
Query: 718 LKKMKELEKQKRIKR-----NQQLEAIAKE 742
+ K E + ++ N+ L + KE
Sbjct: 1227 VGMKKHEENEAKLTMQITALNENLGTVKKE 1256
Score = 56.2 bits (134), Expect = 1e-07
Identities = 178/851 (20%), Positives = 332/851 (39%), Gaps = 157/851 (18%)
Query: 76 KTSEQIEDHDEIY----AEAQELVNDWLDTKLKQELASEEEGDAK-NTVSSVTIMPEANG 130
KT +Q ++ + A+ +E ND L+Q L + D K + ++ + N
Sbjct: 485 KTKQQHQEQQALQQSTTAKLREAQND-----LEQVLRQIGDKDQKIQNLEALLQKSKENI 539
Query: 131 HLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRL 190
L + +DL ++ E T V ++ L KN + E + + + K Q + +
Sbjct: 540 SLLEKEREDLYAKIQAGEGETAV---LNQLQEKN---HTLQEQVTQLTEKLKNQSESHKQ 593
Query: 191 TMEMRHKQVKENR--LRREK------ELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEA 242
E H QV+E + LR + E + L +S +Q +Q + K + L +
Sbjct: 594 AQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLS 653
Query: 243 KKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEK 302
+ + QR ++ + + ++ K+QE N + + Q T L D+++
Sbjct: 654 AEAAKTAQRADLQNHLDTAQNA--------LQDKQQELNKITTQ---LDQVTAKLQDKQE 702
Query: 303 MVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDH-RIKLGKAGTLSDWKIQLKV-- 359
+ + LKE + + +Q + KL D +K K L D + Q ++
Sbjct: 703 HCSQLESHLKEYK-EKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNT 761
Query: 360 ---LRAWRDYTRFQKLERE-TQALENDLRE-----ENRKQQLATEYNRKQVLRHCFTEWQ 410
LRA + ++ ++E+E + DL++ E+ KQ+L + KQ+L+ F
Sbjct: 762 DLELRA-TELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDF---- 816
Query: 411 HWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGL-SGISLPEEATAMVGPPVKN 469
E L +E + EE ++ + K+ L + +S ++ + V +KN
Sbjct: 817 -----ETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKN 871
Query: 470 GQETAVPPLWEKPPLGSSGCMLS-PPLGRTTTGNLQGSLQNV---------SLSAPGNKQ 519
+ +EK +L + LQ ++N SL
Sbjct: 872 SKSE-----FEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEAS 926
Query: 520 HKT---LGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQ--- 573
H+ L + Q + TL+ ++K E G+ + +Q +KQ + LQ +
Sbjct: 927 HQLKLELNSMQEQLIQAQNTLKQ-NEKEEQQLQGNINELKQSSEQK-KKQIEALQGELKI 984
Query: 574 ---QKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNS------ 624
QKT LE K QL +A LA + + +L E+ T + L +
Sbjct: 985 AVLQKTELENKLQQQLTQAA----QELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRES 1040
Query: 625 -------------PVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKA--------MEE 663
S E +RN + + ++L T L+ ++E
Sbjct: 1041 ELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQE 1100
Query: 664 R--AIQRAECRRILAEKKKKQEEEKLAQLKA----QEEERQKREAEEKEAQLERKREEKR 717
R A+Q + + L EK+ E+ KLA+++ QE+E K E K +LE +E
Sbjct: 1101 RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITN 1160
Query: 718 LKKMKELEKQKRI----------------KRNQQL---------EAIAKEHYERVL---- 748
LK K+L Q+++ KRNQQ+ E + KE E+
Sbjct: 1161 LKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHS 1220
Query: 749 -LRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYS 807
+++K + K ++K +Q+ + +L +K +Q SQ ++ Q D
Sbjct: 1221 EIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKE----WQSSQRRVSELEKQTDDLRG 1276
Query: 808 QI-LLKRVIQS 817
+I +L+ +Q+
Sbjct: 1277 EIAVLEATVQN 1287
Score = 52.4 bits (124), Expect = 2e-06
Identities = 170/859 (19%), Positives = 345/859 (40%), Gaps = 135/859 (15%)
Query: 72 ITDLKTSEQIEDHDEIYAEAQELVNDWLDTK-----LKQELAS---------EEEGDAKN 117
+ D T E+ + +++ E ++L + + ++ L+ ELA +E K+
Sbjct: 236 LMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKS 295
Query: 118 TVSSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMED-LGR 176
+V+ +T + K D E+ E + +K I LH+ +D ++ L
Sbjct: 296 SVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSA 355
Query: 177 KENQ--------DKKQQKDPRLTMEMRHKQVKENRLRRE-KELEYQRIEKTLK------- 220
E +K + +L E+ + K L+ E K+L+ QR EK
Sbjct: 356 SETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSE 415
Query: 221 ----KSAFLEAQCLVQEE----KKRKALEAKK---EEEEIQREMVKLRREIIERRRTVKA 269
S LE + + E K+++ L ++K +E+++ +KL R + + V
Sbjct: 416 INQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTN 475
Query: 270 AWKIEKKRQEENSQNSSEKVMFQST-----HILPDEEKMV-----KERKRKLKEVLIQTF 319
+ +++ + + Q+ ++ + QST D E+++ K++K + E L+Q
Sbjct: 476 STELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKS 535
Query: 320 KENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQAL 379
KEN ++ + L +I+ G+ T ++Q K ++T +++ + T+ L
Sbjct: 536 KENISLLEK-----EREDLYAKIQAGEGETAVLNQLQEK------NHTLQEQVTQLTEKL 584
Query: 380 ENDLREENRKQQLATEYNRKQVLR-HCFTEWQHWHGAELLKRELALTKEETRKK---MDA 435
+N + E+ KQ +++ Q + H E EL E+++K +D
Sbjct: 585 KN--QSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDI 642
Query: 436 LLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPP-LGSSGCMLSPP 494
++A + LSA E A ++N +TA L +K L L
Sbjct: 643 QIKAKTELLLSA---------EAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQV 693
Query: 495 LGRTT--------------------------TGNLQGSLQNV---SLSAPGNKQHKTLGA 525
+ T L+G ++ + SL +K+
Sbjct: 694 TAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDL 753
Query: 526 EPSQQPGSNETLRTTSQ----KAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELK 581
+ +Q ++ LR T + E + + + +E K+KL +Q++ LK
Sbjct: 754 QQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILK 813
Query: 582 KNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSL 641
++ + + +H Q+ + + + + M S V ++ +NS
Sbjct: 814 QDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSK 873
Query: 642 SGLRRKPKQ----LMTPHPILKAMEERA-IQRAECRRILAEKKKKQEEEKLA--QLKAQE 694
S ++ ++ ++ K ++ + +Q + E KK E+EK A QLK +
Sbjct: 874 SEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLEL 933
Query: 695 EERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGL 754
Q++ + + + ++EE++L+ KQ ++ +Q+EA+ E + +L+K L
Sbjct: 934 NSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGE-LKIAVLQKTEL 992
Query: 755 EPWKRLRMQSKQNIQ--VAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFY---SQI 809
E +L+ Q Q Q AE+ LQ Y ++SQE+ K Q+D FY S++
Sbjct: 993 E--NKLQQQLTQAAQELAAEKEKISVLQNNY-----EKSQETF--KQLQSD-FYGRESEL 1042
Query: 810 LLKRVIQSWLQYVIDLQEE 828
L R ++ + L +E
Sbjct: 1043 LATRQDLKSVEEKLSLAQE 1061
Score = 37.4 bits (85), Expect = 0.066
Identities = 54/216 (25%), Positives = 99/216 (45%), Gaps = 39/216 (18%)
Query: 196 HKQVKENRLRREKELEYQRIEKTLKKSAFLEAQ-------CLVQEEKKRKAL---EAKKE 245
++++K ++L KE+ + K L LE Q V++EK+ + + + KKE
Sbjct: 1144 NEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKE 1203
Query: 246 EEEIQREMV----KLRREIIERRRTVKAAWKIEKKRQEE----NSQNSSEKVMFQSTHIL 297
EEE+++E + KL EI E+ +K + E K + N + K +QS+
Sbjct: 1204 EEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRR 1263
Query: 298 PDE-EKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQ 356
E EK + + ++ +++ +N Q ++R +L+ +K G K+Q
Sbjct: 1264 VSELEKQTDDLRGEI--AVLEATVQNNQDERR-------ALLERCLK----GEGEIEKLQ 1310
Query: 357 LKVLRAWRDYTRFQKLERETQALENDLREENRKQQL 392
KVL R KL+ T A++ +L EN+ Q+
Sbjct: 1311 TKVLELQR------KLDNTTAAVQ-ELGRENQSLQI 1339
Score = 34.3 bits (77), Expect = 0.56
Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 2/108 (1%)
Query: 647 KPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKE 706
KP L+T E+ ++ A+ ++ K E+K AQL + + + + EE+
Sbjct: 125 KPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEER- 183
Query: 707 AQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGL 754
L E+K + +EL K+ + ++ + E + + E V + KK L
Sbjct: 184 -SLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKEL 230
Score = 33.1 bits (74), Expect = 1.2
Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 7/108 (6%)
Query: 681 KQEEEKLAQLKAQEEERQ------KREAEEKEAQLERKREEK-RLKKMKELEKQKRIKRN 733
K+E EK L+ QE + E + E QLE + E +K+MK+L +QK +
Sbjct: 110 KKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLA 169
Query: 734 QQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQR 781
++ I ++ E LR+ + RL + + V ++ + LQR
Sbjct: 170 TEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQR 217
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 59.7 bits (143), Expect = 1e-08
Identities = 61/277 (22%), Positives = 128/277 (46%), Gaps = 20/277 (7%)
Query: 538 RTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHAL 597
R T + +P C R + +++ ++L+ Q+ +E K +L E + E L
Sbjct: 522 RNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQK---VEEDKRRRLEEVKLKREERL 578
Query: 598 AVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPI 657
+ + +EE+ + Q+ TE + R + ++K
Sbjct: 579 RKVLQARERVEQMKEEKKK--QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK----- 631
Query: 658 LKAMEERAIQRAECRRI--LAEKKKKQEEEKLAQLKAQEEERQKREAEE-----KEAQLE 710
++ +E R Q E RR+ L ++++++ ++L Q K +EE+ + R+A E ++ + E
Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE 691
Query: 711 RKREEKRLKKMKELEKQKRIKRNQQLEAIAKE---HYERVLLRKKGLEPWKRLRMQSKQN 767
R+ +E+R ++ +E E++++ +R Q+ + +E ER+ ++ E K LR+Q +Q
Sbjct: 692 RREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQL 751
Query: 768 IQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQ 804
+ EE Q++ Q QE A++ A A +
Sbjct: 752 QRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788
Score = 55.1 bits (131), Expect = 3e-07
Identities = 63/252 (25%), Positives = 120/252 (47%), Gaps = 25/252 (9%)
Query: 187 DPRLTMEMRHKQVKENRLRREKELEYQRIEKTLK-KSAFLEAQCLVQEEKKRKALEAKKE 245
DP+ + + +Q EN LRR++E E R +K + K LE L +EE+ RK L+A++
Sbjct: 529 DPKCSFVEKERQRLEN-LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 587
Query: 246 EEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVK 305
E+++ E +++ IE ++ + K EK ++E ++ ++K + + V+
Sbjct: 588 VEQMKEE----KKKQIE-QKFAQIDEKTEKAKEERLAEEKAKK------KAAAKKMEEVE 636
Query: 306 ERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRD 365
R+++ +E + + ++ ++R+ K + + +L KA + K L R+
Sbjct: 637 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA-------EAKRLAEQRE 689
Query: 366 YTRFQKLERETQALENDLREENRKQQ----LATEYNRKQVLRHCFTEWQHWHGA-ELLKR 420
R ++ RE + E + RE+ R++Q E R+Q E Q A L K
Sbjct: 690 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 749
Query: 421 ELALTKEETRKK 432
+L EE +KK
Sbjct: 750 QLQRELEEKKKK 761
Score = 53.5 bits (127), Expect = 9e-07
Identities = 51/186 (27%), Positives = 93/186 (50%), Gaps = 17/186 (9%)
Query: 144 LEEEEESTTVQKF--IDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKE 201
++EE++ QKF ID K + + E+ +K+ KK ++ +E R KQ +E
Sbjct: 591 MKEEKKKQIEQKFAQIDEKTEK-AKEERLAEEKAKKKAAAKKMEE-----VEARRKQEEE 644
Query: 202 NRLRR--EKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRRE 259
R R ++E E +R ++ L+K E +E+ RKA EAK+ E+ ++E + R
Sbjct: 645 ARRLRWLQQEEEERRHQELLQKKKEEE------QERLRKAAEAKRLAEQREQERREQERR 698
Query: 260 IIERRRTVKAAW-KIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQT 318
ERR + + E++RQ + E+ Q+ L + EK ++ +K +L+ L +
Sbjct: 699 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 758
Query: 319 FKENQQ 324
K+ +Q
Sbjct: 759 KKKEEQ 764
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/209 (21%), Positives = 93/209 (44%), Gaps = 15/209 (7%)
Query: 79 EQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFD 138
EQ+++ + E + D K K+E +EE+ K M E K ++
Sbjct: 589 EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK---MEEVEARRKQEEEA 645
Query: 139 DLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQ 198
+L++EEE Q+ + + + R Q ++++++ + R +Q
Sbjct: 646 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ 705
Query: 199 VKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRR 258
+ + RRE+E + E+ ++ L+A+ +QE + KAL +KE+ L+R
Sbjct: 706 ERREQERREQERQLAEQERRREQER-LQAERELQE--REKALRLQKEQ---------LQR 753
Query: 259 EIIERRRTVKAAWKIEKKRQEENSQNSSE 287
E+ E+++ + E++ QEE + + E
Sbjct: 754 ELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
Score = 39.7 bits (91), Expect = 0.013
Identities = 75/323 (23%), Positives = 140/323 (43%), Gaps = 68/323 (21%)
Query: 585 QLAEAQWAAEHALAVTEAQSHL----LSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNS 640
Q A + + + A++ + + HL L PR + P +SP P ++ R
Sbjct: 445 QSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTP-------SSPC--PASKVVRPLRTF 495
Query: 641 LSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKK-KKQEEEKLAQLKAQEEERQK 699
L ++R + LMTP +++ + I+R R+ + ++E ++L L+ +EE Q
Sbjct: 496 LHTVQRN-QMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQL 554
Query: 700 REAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR 759
R + +E + R+ EE +LK+ + L K + A+E E++ KK K+
Sbjct: 555 RRQKVEEDK-RRRLEEVKLKREERLRKVLQ----------ARERVEQMKEEKK-----KQ 598
Query: 760 LRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWL 819
+ + Q + E+ ++ L + +++ A+KM + + Q R ++ WL
Sbjct: 599 IEQKFAQIDEKTEK------AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR-WL 651
Query: 820 QYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTW 879
Q QEE + LQKK K + Q + AAE
Sbjct: 652 Q-----QEEEERRHQELLQKK------------KEEEQERLRKAAEA------------- 681
Query: 880 KKFVKFMKEERVKEERRQQLRRK 902
K+ + ++ER ++ERR+Q RR+
Sbjct: 682 KRLAEQREQERREQERREQERRE 704
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 59.7 bits (143), Expect = 1e-08
Identities = 83/376 (22%), Positives = 162/376 (43%), Gaps = 32/376 (8%)
Query: 25 RKPSPKPTFGPDSVEHWIKRVEKASEFAVSNAFFTRNSDLPRSPWGQITDLKTSEQIEDH 84
RKP D V I E S + + R W + + T E++E
Sbjct: 74 RKPETIQLITRDMVRELIVPTEDPS----GESLIISPEEFERIKWA--SHVLTREELEAR 127
Query: 85 DEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYL 144
D+ + + +E D + T+ K E + +S + + + + + L +
Sbjct: 128 DQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKL--RM 185
Query: 145 EEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRL 204
E+EEE + K I + + D+ ++E +++ Q + ++ RL M ++ K +
Sbjct: 186 EQEEELKDMSKIILNAKCHAIRDAQILE---KQQIQKELDTEEKRLDQMMEVERQKS--I 240
Query: 205 RREKELEYQRIEKTLK-KSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREII-- 261
+R++ELE +R E+ ++ + +E QEE+ A + ++E+E++ M +L+ E +
Sbjct: 241 QRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKD 300
Query: 262 -ERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFK 320
ERR+ K + E KR N +N +K + L D+ M +K+ +E + +
Sbjct: 301 MERRQQQKLKMQAEIKR--INDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQ 358
Query: 321 ENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDY----TRFQKLERET 376
E + +K K I R KA D++ + LRA R+ +++ E+E
Sbjct: 359 ERIRREK------EKEIARLRAMQEKA---QDYQAEQDALRAKRNQEVADREWRRKEKEN 409
Query: 377 QALENDLREENRKQQL 392
+ + E RK +L
Sbjct: 410 ARKKMETEAELRKSRL 425
Score = 53.5 bits (127), Expect = 9e-07
Identities = 58/243 (23%), Positives = 116/243 (47%), Gaps = 19/243 (7%)
Query: 632 EGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLK 691
E D+ + + ++ + + + L +EE A +RA+ A K + ++EE+L +
Sbjct: 136 EATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMS 195
Query: 692 ------AQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYE 745
R + E+++ Q E EEKRL +M E+E+QK I+R ++LE K E
Sbjct: 196 KIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELE--RKRREE 253
Query: 746 RVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKM--AQAD 803
R+ R++ +E ++ ++ +AE+ +++ ML + ++ QE + M Q
Sbjct: 254 RIRGRRQIVE---QMEKNQEERSLLAEQREQ---EKEQMLEYMEQLQEEDLKDMERRQQQ 307
Query: 804 QFYSQILLKRVIQSWLQYVIDL--QEEVR-KFCVHFLQKKIFRAWFNMVREVKIDSQGKH 860
+ Q +KR+ + +L QE++ + + F +KK+ R + +I + +
Sbjct: 308 KLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEK 367
Query: 861 EIA 863
EIA
Sbjct: 368 EIA 370
Score = 51.6 bits (122), Expect = 3e-06
Identities = 87/335 (25%), Positives = 150/335 (44%), Gaps = 66/335 (19%)
Query: 561 QLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQM 620
Q++EKQ Q Q++ E K+ Q+ E + + Q L K REE R +
Sbjct: 210 QILEKQ----QIQKELDTEEKRLDQMMEVERQKS-----IQRQEELERKRREERIRGRRQ 260
Query: 621 LVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPH------PILKAMEERAIQR----AE 670
+V E + R+ L+ R + K+ M + LK ME R Q+ AE
Sbjct: 261 IVEQ------MEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAE 314
Query: 671 CRRILAEKKKKQEEEKLAQLKAQE-----------EERQKREAE-EKEAQLERKREEKRL 718
+RI E +K++ A+L AQE +++ REAE E E + R+ +EK +
Sbjct: 315 IKRINDENQKQK-----AELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEI 369
Query: 719 KKMKELEKQK----------RIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNI 768
+++ ++++ R KRNQ++ E+ RKK +E LR +
Sbjct: 370 ARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKK-METEAELRKSRLE-- 426
Query: 769 QVAEEHYSLFLQRKYMLTWFQRSQESLARKM-AQADQFYSQIL-LKRVIQSWLQYVIDLQ 826
QVA + ++L +Q QR ++ R + AQ +Q + L ++ LQ+ +L+
Sbjct: 427 QVAFKEHALAVQ-------VQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELR 479
Query: 827 EEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHE 861
+VR+ +Q +I A F R +K ++Q + E
Sbjct: 480 RQVRENQQKEVQNRI--ATFEEGRRLKEEAQKRRE 512
Score = 41.2 bits (95), Expect = 0.005
Identities = 55/264 (20%), Positives = 119/264 (45%), Gaps = 26/264 (9%)
Query: 643 GLRRKPK--QLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR 700
GL RKP+ QL+T + + + E I E+ ++ + + + E R +
Sbjct: 71 GLDRKPETIQLITRDMVRELIVPTEDPSGESLIISPEEFERIKWASHVLTREELEARDQA 130
Query: 701 EAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRL 760
+EKEA ++ K++ K KE+ K+ LE +AKE + +L R +L
Sbjct: 131 FKKEKEATMDAVMTRKKIMKQKEMVWNNN-KKLSDLEEVAKERAQNLLQRA------NKL 183
Query: 761 RMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQ 820
RM+ ++ + ++ + L K R + L ++ Q + + L ++++ Q
Sbjct: 184 RMEQEEEL---KDMSKIILNAKCHAI---RDAQILEKQQIQKELDTEEKRLDQMMEVERQ 237
Query: 821 YVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWK 880
I QEE+ + +++ R +V +++ + + + +A + +
Sbjct: 238 KSIQRQEELER----KRREERIRGRRQIVEQMEKNQEERSLLAEQREQEK------EQML 287
Query: 881 KFVKFMKEERVKE-ERRQQLRRKV 903
++++ ++EE +K+ ERRQQ + K+
Sbjct: 288 EYMEQLQEEDLKDMERRQQQKLKM 311
Score = 37.4 bits (85), Expect = 0.066
Identities = 43/223 (19%), Positives = 89/223 (39%), Gaps = 8/223 (3%)
Query: 564 EKQKKKLQEQQKT----ILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQ 619
+KQK +L Q+K ++E K EA++ AE E + + +E
Sbjct: 323 QKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDY 382
Query: 620 MLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKK 679
+ + + +D K++ T + K+ E Q A LA +
Sbjct: 383 QAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLE---QVAFKEHALAVQV 439
Query: 680 KKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAI 739
++ +E L+AQ E+ +K EE++ R + L++ +QK ++
Sbjct: 440 QRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEE 499
Query: 740 AKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRK 782
+ E R++ ++ KR +++ + + E+ Y + +RK
Sbjct: 500 GRRLKEEAQKRRERIDEIKRKKLEELRATGLPEK-YCIEAERK 541
Score = 34.7 bits (78), Expect = 0.43
Identities = 92/498 (18%), Positives = 192/498 (38%), Gaps = 99/498 (19%)
Query: 237 RKALEAK----KEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQ--EENSQNSSEKVM 290
R+ LEA+ K+E+E + V R++I++++ V W KK EE ++ ++ ++
Sbjct: 121 REELEARDQAFKKEKEATMDAVMTRKKIMKQKEMV---WNNNKKLSDLEEVAKERAQNLL 177
Query: 291 FQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTL 350
++ + ++E+ +K+ + + ++ Q +K+
Sbjct: 178 QRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQ------------------- 218
Query: 351 SDWKIQLKVLRAWRDYTRFQKLERETQALENDLREEN--RKQQLATEYNRKQVLRHCFTE 408
+ + K L + R + ++R+ + LE REE ++Q+ + + Q R E
Sbjct: 219 KELDTEEKRLDQMMEVERQKSIQRQEE-LERKRREERIRGRRQIVEQMEKNQEERSLLAE 277
Query: 409 WQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVK 468
+ ++L+ L +EE K M+ Q + ++ + ++A +
Sbjct: 278 QREQEKEQMLEYMEQL-QEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLA----- 331
Query: 469 NGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPS 528
QE + ++ + + ++ A + + + E
Sbjct: 332 --QEKLADQMV-----------------------MEFTKKKMAREAEFEAEQERIRREKE 366
Query: 529 QQPGSNETLRTTSQ--KAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQL 586
++ ++ +Q +AE L N+ V ++ K+K+ +++ +T EL+K+ +L
Sbjct: 367 KEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKS-RL 425
Query: 587 AEAQWAAEHALAV------------TEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGR 634
+ + EHALAV AQ + K R EE + GR
Sbjct: 426 EQVAF-KEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKK-------------ATGR 471
Query: 635 SDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQE 694
N L R+ +Q K ++ R E RR+ E +K++E + K E
Sbjct: 472 LQHANELRRQVRENQQ--------KEVQNRIATFEEGRRLKEEAQKRRERIDEIKRKKLE 523
Query: 695 EERQKREAEEKEAQLERK 712
E R E+ + ERK
Sbjct: 524 ELRATGLPEKYCIEAERK 541
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 59.3 bits (142), Expect = 2e-08
Identities = 55/250 (22%), Positives = 120/250 (48%), Gaps = 17/250 (6%)
Query: 565 KQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNS 624
++K++ ++ ++ +E K +L E + E L + + +EE+ + Q+
Sbjct: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK--QIEQKF 599
Query: 625 PVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRI--LAEKKKKQ 682
TE + R + ++K ++ +E R Q E RR+ L ++++++
Sbjct: 600 AQIDEKTEKAKEERLAEEKAKKKAAAKK-----MEEVEARRKQEEEARRLRWLQQEEEER 654
Query: 683 EEEKLAQLKAQEEERQKREAEE-----KEAQLERKREEKRLKKMKELEKQKRIKRNQQLE 737
++L Q K +EE+ + R+A E ++ + ER+ +E+R ++ +E E++++ +R Q+ +
Sbjct: 655 RHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQ 714
Query: 738 AIAKE---HYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQES 794
+E ER+ ++ E K LR+Q +Q + EE Q++ Q QE
Sbjct: 715 LAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
Query: 795 LARKMAQADQ 804
A++ A A +
Sbjct: 775 KAKEAAGASK 784
Score = 53.5 bits (127), Expect = 9e-07
Identities = 51/186 (27%), Positives = 93/186 (50%), Gaps = 17/186 (9%)
Query: 144 LEEEEESTTVQKF--IDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKE 201
++EE++ QKF ID K + + E+ +K+ KK ++ +E R KQ +E
Sbjct: 587 MKEEKKKQIEQKFAQIDEKTEK-AKEERLAEEKAKKKAAAKKMEE-----VEARRKQEEE 640
Query: 202 NRLRR--EKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRRE 259
R R ++E E +R ++ L+K E +E+ RKA EAK+ E+ ++E + R
Sbjct: 641 ARRLRWLQQEEEERRHQELLQKKKEEE------QERLRKAAEAKRLAEQREQERREQERR 694
Query: 260 IIERRRTVKAAW-KIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQT 318
ERR + + E++RQ + E+ Q+ L + EK ++ +K +L+ L +
Sbjct: 695 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Query: 319 FKENQQ 324
K+ +Q
Sbjct: 755 KKKEEQ 760
Score = 52.4 bits (124), Expect = 2e-06
Identities = 63/256 (24%), Positives = 121/256 (47%), Gaps = 25/256 (9%)
Query: 183 KQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLK-KSAFLEAQCLVQEEKKRKALE 241
K+ R+ + + +Q EN LRR++E E R +K + K LE L +EE+ RK L+
Sbjct: 521 KRNTPLRMDPKEKERQRLEN-LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
Query: 242 AKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEE 301
A++ E+++ E +++ IE ++ + K EK ++E ++ ++K +
Sbjct: 580 ARERVEQMKEE----KKKQIE-QKFAQIDEKTEKAKEERLAEEKAKK------KAAAKKM 628
Query: 302 KMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLR 361
+ V+ R+++ +E + + ++ ++R+ K + + +L KA + K L
Sbjct: 629 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA-------EAKRLA 681
Query: 362 AWRDYTRFQKLERETQALENDLREENRKQQ----LATEYNRKQVLRHCFTEWQHWHGA-E 416
R+ R ++ RE + E + RE+ R++Q E R+Q E Q A
Sbjct: 682 EQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALR 741
Query: 417 LLKRELALTKEETRKK 432
L K +L EE +KK
Sbjct: 742 LQKEQLQRELEEKKKK 757
Score = 50.8 bits (120), Expect = 6e-06
Identities = 85/400 (21%), Positives = 159/400 (39%), Gaps = 53/400 (13%)
Query: 419 KRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPL 478
K+E + + R + A+ G++ + L E VG K E A P
Sbjct: 327 KQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVA 386
Query: 479 WEKPPLGSSGCMLSPPLGRT----TTGNLQGSLQNVSLSAPGNKQHKTLGAE-PSQQPGS 533
+P + + S P T +T N + + + + G ++ KT A+ P + P S
Sbjct: 387 AAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQS 446
Query: 534 NETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQ---QKTILELKKNLQLAEAQ 590
R+ Q L +H+ ++L + K K + L+ L
Sbjct: 447 ARRKRSYKQAVSELD----EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLH----- 497
Query: 591 WAAEHALAVTEAQSHLLSKPREEEPRTCQMLV--NSPVASPGTEGRSDSRNSLSGLRRKP 648
T ++ +L P + + N+P+ + + R L LRRK
Sbjct: 498 ---------TVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM---DPKEKERQRLENLRRKE 545
Query: 649 KQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQ 708
+ ++ + R ++ + +R +K Q E++ Q+K E +K++ E+K AQ
Sbjct: 546 EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMK----EEKKKQIEQKFAQ 601
Query: 709 LERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNI 768
++ K E+ + +++ E EK K+ +A AK+ E V R+K E +RLR ++
Sbjct: 602 IDEKTEKAKEERLAE-EKAKK-------KAAAKK-MEEVEARRKQEEEARRLRWLQQEE- 651
Query: 769 QVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQ 808
E + LQ+K + ++ RK A+A + Q
Sbjct: 652 --EERRHQELLQKK------KEEEQERLRKAAEAKRLAEQ 683
Score = 47.0 bits (110), Expect = 8e-05
Identities = 38/141 (26%), Positives = 68/141 (48%), Gaps = 23/141 (16%)
Query: 560 QQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQ 619
Q+L++K+K++ QE+ + + AEA+ AE Q + RE+E R
Sbjct: 657 QELLQKKKEEEQERLR---------KAAEAKRLAEQREQERREQERREQERREQERRE-- 705
Query: 620 MLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEER-AIQRAECRRILAEK 678
E R R RR+ ++ + L+ E+ +Q+ + +R L EK
Sbjct: 706 -----------QERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Query: 679 KKKQEEEKLAQLKAQEEERQK 699
KKK+E+++LA+ + QEE+ +K
Sbjct: 755 KKKEEQQRLAERQLQEEQEKK 775
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/209 (21%), Positives = 93/209 (44%), Gaps = 15/209 (7%)
Query: 79 EQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFD 138
EQ+++ + E + D K K+E +EE+ K M E K ++
Sbjct: 585 EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK---MEEVEARRKQEEEA 641
Query: 139 DLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQ 198
+L++EEE Q+ + + + R Q ++++++ + R +Q
Sbjct: 642 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQ 701
Query: 199 VKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRR 258
+ + RRE+E + E+ ++ L+A+ +QE + KAL +KE+ L+R
Sbjct: 702 ERREQERREQERQLAEQERRREQER-LQAERELQE--REKALRLQKEQ---------LQR 749
Query: 259 EIIERRRTVKAAWKIEKKRQEENSQNSSE 287
E+ E+++ + E++ QEE + + E
Sbjct: 750 ELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 46.2 bits (108), Expect = 1e-04
Identities = 76/322 (23%), Positives = 145/322 (45%), Gaps = 70/322 (21%)
Query: 585 QLAEAQWAAEHALAVTEAQSHL----LSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNS 640
Q A + + + A++ + + HL L PR + P +SP P ++ R
Sbjct: 445 QSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTP-------SSPC--PASKVVRPLRTF 495
Query: 641 LSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKR 700
L ++R + LMTP +++ + I+R R+ ++K++Q E L R+K
Sbjct: 496 LHTVQRN-QMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENL---------RRKE 545
Query: 701 EAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRL 760
EAE+ Q + + +RL+++K L++++R+++ Q A+E E++ KK K++
Sbjct: 546 EAEQLRRQKVEEDKRRRLEEVK-LKREERLRKVLQ----ARERVEQMKEEKK-----KQI 595
Query: 761 RMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQ 820
+ Q + E+ ++ L + +++ A+KM + + Q R ++ WLQ
Sbjct: 596 EQKFAQIDEKTEK------AKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR-WLQ 648
Query: 821 YVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWK 880
QEE + LQKK K + Q + AAE K
Sbjct: 649 -----QEEEERRHQELLQKK------------KEEEQERLRKAAEA-------------K 678
Query: 881 KFVKFMKEERVKEERRQQLRRK 902
+ + ++ER ++ERR+Q RR+
Sbjct: 679 RLAEQREQERREQERREQERRE 700
Score = 36.6 bits (83), Expect = 0.11
Identities = 48/182 (26%), Positives = 82/182 (45%), Gaps = 42/182 (23%)
Query: 564 EKQKKKLQEQQKTILEL--KKNLQLAEAQWAAEHALAVTEAQSH--LLSKPREEEPRTCQ 619
EK KKK ++ +E K+ + +W + E + H LL K +EEE +
Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE----EERRHQELLQKKKEEEQ---E 669
Query: 620 MLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKK 679
L + A E R R RR+ ++ + E R +R E R LAE++
Sbjct: 670 RLRKAAEAKRLAEQREQERREQE--RREQER--------REQERREQERREQERQLAEQE 719
Query: 680 KKQEEEKLA-----------------QLKAQ-EEERQKREAEEKEAQLERKREEKRLKKM 721
+++E+E+L QL+ + EE+++K EE++ ER+ +E++ KK
Sbjct: 720 RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK---EEQQRLAERQLQEEQEKKA 776
Query: 722 KE 723
KE
Sbjct: 777 KE 778
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.128 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,124,555
Number of Sequences: 37866
Number of extensions: 1779555
Number of successful extensions: 39297
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 552
Number of HSP's successfully gapped in prelim test: 1158
Number of HSP's that attempted gapping in prelim test: 12021
Number of HSP's gapped (non-prelim): 12738
length of query: 936
length of database: 18,247,518
effective HSP length: 112
effective length of query: 824
effective length of database: 14,006,526
effective search space: 11541377424
effective search space used: 11541377424
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.