Guide to the Human Genome
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Search of human proteins with 24307929

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24307929 Opa interacting protein 5 [Homo sapiens]
         (229 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24307929 Opa interacting protein 5 [Homo sapiens]                  466   e-132
gi|9506437 chromosome 21 open reading frame 45 [Homo sapiens]          41   7e-04
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    30   1.7  
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    30   1.7  
gi|4885323 G protein-coupled receptor 37 [Homo sapiens]                30   2.2  
gi|98961138 ZXD family zinc finger C isoform 2 [Homo sapiens]          30   2.2  
gi|98961133 ZXD family zinc finger C isoform 1 [Homo sapiens]          30   2.2  
gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens]      29   3.8  
gi|31377634 guanylate binding protein 4 [Homo sapiens]                 28   5.0  
gi|46409504 hypothetical protein LOC400165 [Homo sapiens]              28   5.0  
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  28   6.5  
gi|239048909 checkpoint with forkhead and ring finger domains is...    28   8.5  
gi|239048905 checkpoint with forkhead and ring finger domains is...    28   8.5  
gi|239048862 checkpoint with forkhead and ring finger domains is...    28   8.5  
gi|239048792 checkpoint with forkhead and ring finger domains is...    28   8.5  
gi|239756937 PREDICTED: hypothetical protein [Homo sapiens]            28   8.5  
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    28   8.5  
gi|239048907 checkpoint with forkhead and ring finger domains is...    28   8.5  
gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]                       28   8.5  
gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]                         28   8.5  

>gi|24307929 Opa interacting protein 5 [Homo sapiens]
          Length = 229

 Score =  466 bits (1198), Expect = e-132
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MAAQPLRHRSRCATPPRGDFCGGTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEP 60
           MAAQPLRHRSRCATPPRGDFCGGTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEP
Sbjct: 1   MAAQPLRHRSRCATPPRGDFCGGTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEP 60

Query: 61  AAGPQLPSWLQPERCAVFQCAQCHAVLADSVHLAWDLSRSLGAVVFSRVTNNVVLEAPFL 120
           AAGPQLPSWLQPERCAVFQCAQCHAVLADSVHLAWDLSRSLGAVVFSRVTNNVVLEAPFL
Sbjct: 61  AAGPQLPSWLQPERCAVFQCAQCHAVLADSVHLAWDLSRSLGAVVFSRVTNNVVLEAPFL 120

Query: 121 VGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIV 180
           VGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIV
Sbjct: 121 VGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLLKTKAIV 180

Query: 181 NASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPEN 229
           NASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPEN
Sbjct: 181 NASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKILSEVTPDQSKPEN 229


>gi|9506437 chromosome 21 open reading frame 45 [Homo sapiens]
          Length = 233

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 7/149 (4%)

Query: 73  ERCAVFQCAQCHAVLADSVHLAWDLSRS-LGAVVFSRVTNNVVLEAPFLVGIEGSLKGST 131
           ER  VF C+ C   L DS  L+W  S+     ++   V+ NV ++    +       G  
Sbjct: 78  ERPLVFLCSGCRRPLGDS--LSWVASQEDTNCILLRCVSCNVSVDKEQKLSKREKENGCV 135

Query: 132 YNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSSDKMVCYLL-KTKAIVNASEMDIQNV 190
              L C  C + +G+    T   L   R  FCLS + +  Y+L  ++  + + + ++ N+
Sbjct: 136 LETLCCAGCSLNLGYVYRCTPKNLDYKRDLFCLSVEAIESYVLGSSEKQIVSEDKELFNL 195

Query: 191 PLSEKIAELKEKIVLTHNRLKSLMKILSE 219
              E   E+++ +    + LK+L   L E
Sbjct: 196 ---ESRVEIEKSLTQMEDVLKALQMKLWE 221


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform
           5 [Homo sapiens]
          Length = 6907

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 12/52 (23%)

Query: 184 EMDIQNVPLSE------------KIAELKEKIVLTHNRLKSLMKILSEVTPD 223
           +MDIQN+   E            KI E KEK+ +   +L + +K L++V+PD
Sbjct: 792 QMDIQNISSQESFQHVLTTGLQAKIQEAKEKVQINVVKLIAALKNLTDVSPD 843


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform
           1 [Homo sapiens]
          Length = 6885

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 12/52 (23%)

Query: 184 EMDIQNVPLSE------------KIAELKEKIVLTHNRLKSLMKILSEVTPD 223
           +MDIQN+   E            KI E KEK+ +   +L + +K L++V+PD
Sbjct: 792 QMDIQNISSQESFQHVLTTGLQAKIQEAKEKVQINVVKLIAALKNLTDVSPD 843


>gi|4885323 G protein-coupled receptor 37 [Homo sapiens]
          Length = 613

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 2/42 (4%)

Query: 31  ASFTTSMEWDTQVVKGSSPLGPAGLGAEEPAAGPQLPSWLQP 72
           A+F     WD     G  P   AG GAE  AAGP  P    P
Sbjct: 78  AAFLAGPSWDLPAAPGRDPA--AGRGAEASAAGPPGPPTRPP 117


>gi|98961138 ZXD family zinc finger C isoform 2 [Homo sapiens]
          Length = 710

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 11/90 (12%)

Query: 1   MAAQPLRHRSRCATPPRGDFCGGTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEP 60
           +A++P +  S  A PP          A+  +S    +  D  V+  S+P GPA  GA  P
Sbjct: 104 LASRPEQGPSGPAAPPGPGVAPAG--AVTISSQDLLVRLDRGVLALSAPPGPATAGAAAP 161

Query: 61  -----AAGPQLPSWLQPERCAVFQCAQCHA 85
                A+GP  P +    RC   QCA   A
Sbjct: 162 RRAPQASGPSTPGY----RCPEPQCALAFA 187


>gi|98961133 ZXD family zinc finger C isoform 1 [Homo sapiens]
          Length = 858

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 11/90 (12%)

Query: 1   MAAQPLRHRSRCATPPRGDFCGGTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEP 60
           +A++P +  S  A PP          A+  +S    +  D  V+  S+P GPA  GA  P
Sbjct: 104 LASRPEQGPSGPAAPPGPGVAPAG--AVTISSQDLLVRLDRGVLALSAPPGPATAGAAAP 161

Query: 61  -----AAGPQLPSWLQPERCAVFQCAQCHA 85
                A+GP  P +    RC   QCA   A
Sbjct: 162 RRAPQASGPSTPGY----RCPEPQCALAFA 187


>gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens]
          Length = 346

 Score = 28.9 bits (63), Expect = 3.8
 Identities = 20/59 (33%), Positives = 23/59 (38%)

Query: 9  RSRCATPPRGDFCGGTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEPAAGPQLP 67
          R R    PRG   GG   A      T   + D +   GS P      G +EP AGP  P
Sbjct: 23 RPRAEPQPRGGRGGGCGWAPFAGCSTRDGDGDEEEYYGSEPRARGLAGDKEPRAGPLPP 81


>gi|31377634 guanylate binding protein 4 [Homo sapiens]
          Length = 640

 Score = 28.5 bits (62), Expect = 5.0
 Identities = 16/51 (31%), Positives = 30/51 (58%)

Query: 167 DKMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMKIL 217
           ++++ + LK +  +   E   ++  L+++I +LKEKI  T N    L+KIL
Sbjct: 561 ERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLRLLKIL 611


>gi|46409504 hypothetical protein LOC400165 [Homo sapiens]
          Length = 121

 Score = 28.5 bits (62), Expect = 5.0
 Identities = 15/57 (26%), Positives = 27/57 (47%), Gaps = 4/57 (7%)

Query: 23 GTERAIDQASFTTSMEWDTQVVKGSSPLGPAGLGAEEPAAGPQLPSWLQPERCAVFQ 79
          G +   D  ++ +S++ D   ++G    GP     +EP    Q  SW QP+ C  ++
Sbjct: 19 GCQPLKDTRAWASSLKMDPAGLEG----GPRDESRDEPPIRAQAASWDQPQGCLTYK 71


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 1/52 (1%)

Query: 40  DTQVVKGSSPLGPAGLGAEEPAAGPQLPSWLQPERCAVFQCAQCHAVLADSV 91
           D Q++     L PA   A  P  G +L  ++      +FQCA C+   +DS+
Sbjct: 841 DPQLMINPFQLDPATAAALAPGLG-ELSPYISDPALKLFQCAVCNKFTSDSL 891


>gi|239048909 checkpoint with forkhead and ring finger domains
           isoform 5 [Homo sapiens]
          Length = 572

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 36/142 (25%), Positives = 50/142 (35%), Gaps = 36/142 (25%)

Query: 71  QPERCAVFQCAQCHAVLADSVHLAWDLSRS-------------LGAVVFSRVTNNVVLEA 117
           Q  R A  QCA C   L    HL W  +R+             LG      V NN   E+
Sbjct: 409 QDPRVAPQQCAVC---LQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYES 465

Query: 118 PFLVGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSS-----DKMVCY 172
             L     +   +  N+L               T + +A  RG F LS      D ++CY
Sbjct: 466 DILKNYLATRGLTWKNML---------------TESLVALQRGVFLLSDYRVTGDTVLCY 510

Query: 173 LLKTKAIVNASEMDIQNVPLSE 194
               ++    +    QN+P SE
Sbjct: 511 CCGLRSFRELTYQYRQNIPASE 532


>gi|239048905 checkpoint with forkhead and ring finger domains
           isoform 3 [Homo sapiens]
          Length = 652

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 36/142 (25%), Positives = 50/142 (35%), Gaps = 36/142 (25%)

Query: 71  QPERCAVFQCAQCHAVLADSVHLAWDLSRS-------------LGAVVFSRVTNNVVLEA 117
           Q  R A  QCA C   L    HL W  +R+             LG      V NN   E+
Sbjct: 489 QDPRVAPQQCAVC---LQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYES 545

Query: 118 PFLVGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSS-----DKMVCY 172
             L     +   +  N+L               T + +A  RG F LS      D ++CY
Sbjct: 546 DILKNYLATRGLTWKNML---------------TESLVALQRGVFLLSDYRVTGDTVLCY 590

Query: 173 LLKTKAIVNASEMDIQNVPLSE 194
               ++    +    QN+P SE
Sbjct: 591 CCGLRSFRELTYQYRQNIPASE 612


>gi|239048862 checkpoint with forkhead and ring finger domains
           isoform 2 [Homo sapiens]
          Length = 663

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 36/142 (25%), Positives = 50/142 (35%), Gaps = 36/142 (25%)

Query: 71  QPERCAVFQCAQCHAVLADSVHLAWDLSRS-------------LGAVVFSRVTNNVVLEA 117
           Q  R A  QCA C   L    HL W  +R+             LG      V NN   E+
Sbjct: 500 QDPRVAPQQCAVC---LQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYES 556

Query: 118 PFLVGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSS-----DKMVCY 172
             L     +   +  N+L               T + +A  RG F LS      D ++CY
Sbjct: 557 DILKNYLATRGLTWKNML---------------TESLVALQRGVFLLSDYRVTGDTVLCY 601

Query: 173 LLKTKAIVNASEMDIQNVPLSE 194
               ++    +    QN+P SE
Sbjct: 602 CCGLRSFRELTYQYRQNIPASE 623


>gi|239048792 checkpoint with forkhead and ring finger domains
           isoform 1 [Homo sapiens]
          Length = 664

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 36/142 (25%), Positives = 50/142 (35%), Gaps = 36/142 (25%)

Query: 71  QPERCAVFQCAQCHAVLADSVHLAWDLSRS-------------LGAVVFSRVTNNVVLEA 117
           Q  R A  QCA C   L    HL W  +R+             LG      V NN   E+
Sbjct: 501 QDPRVAPQQCAVC---LQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYES 557

Query: 118 PFLVGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSS-----DKMVCY 172
             L     +   +  N+L               T + +A  RG F LS      D ++CY
Sbjct: 558 DILKNYLATRGLTWKNML---------------TESLVALQRGVFLLSDYRVTGDTVLCY 602

Query: 173 LLKTKAIVNASEMDIQNVPLSE 194
               ++    +    QN+P SE
Sbjct: 603 CCGLRSFRELTYQYRQNIPASE 624


>gi|239756937 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 294

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 17/39 (43%), Positives = 18/39 (46%)

Query: 46  GSSPLGPAGLGAEEPAAGPQLPSWLQPERCAVFQCAQCH 84
           GSSPL P  LG     AGP  PS L+         AQ H
Sbjct: 153 GSSPLHPVRLGRVRAHAGPAGPSILRVAPHPALPGAQVH 191


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 11/57 (19%)

Query: 22  GGTERAIDQASFTTSMEWDTQVVKG-----------SSPLGPAGLGAEEPAAGPQLP 67
           G  E  +++A  T +   DT+ +             + P  PA LGA+ P  GP  P
Sbjct: 712 GNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTP 768


>gi|239048907 checkpoint with forkhead and ring finger domains
           isoform 4 [Homo sapiens]
          Length = 623

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 36/142 (25%), Positives = 50/142 (35%), Gaps = 36/142 (25%)

Query: 71  QPERCAVFQCAQCHAVLADSVHLAWDLSRS-------------LGAVVFSRVTNNVVLEA 117
           Q  R A  QCA C   L    HL W  +R+             LG      V NN   E+
Sbjct: 460 QDPRVAPQQCAVC---LQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLNNNSYES 516

Query: 118 PFLVGIEGSLKGSTYNLLFCGSCGIPVGFHLYSTHAALAALRGHFCLSS-----DKMVCY 172
             L     +   +  N+L               T + +A  RG F LS      D ++CY
Sbjct: 517 DILKNYLATRGLTWKNML---------------TESLVALQRGVFLLSDYRVTGDTVLCY 561

Query: 173 LLKTKAIVNASEMDIQNVPLSE 194
               ++    +    QN+P SE
Sbjct: 562 CCGLRSFRELTYQYRQNIPASE 583


>gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]
          Length = 365

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 15/48 (31%), Positives = 30/48 (62%), Gaps = 2/48 (4%)

Query: 168 KMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMK 215
           +M+  L  +KA++ + +  IQ   L EKIA L+ + +  H+R++ L++
Sbjct: 279 QMIEQLQNSKAVIQSKDATIQE--LKEKIAYLEAENLEMHDRMEHLIE 324


>gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]
          Length = 390

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 15/48 (31%), Positives = 30/48 (62%), Gaps = 2/48 (4%)

Query: 168 KMVCYLLKTKAIVNASEMDIQNVPLSEKIAELKEKIVLTHNRLKSLMK 215
           +M+  L  +KA++ + +  IQ   L EKIA L+ + +  H+R++ L++
Sbjct: 304 QMIEQLQNSKAVIQSKDATIQE--LKEKIAYLEAENLEMHDRMEHLIE 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,461,636
Number of Sequences: 37866
Number of extensions: 421830
Number of successful extensions: 1490
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1481
Number of HSP's gapped (non-prelim): 24
length of query: 229
length of database: 18,247,518
effective HSP length: 99
effective length of query: 130
effective length of database: 14,498,784
effective search space: 1884841920
effective search space used: 1884841920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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