BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo sapiens] (894 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 1828 0.0 gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 1822 0.0 gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 1380 0.0 gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 1376 0.0 gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 1374 0.0 gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 723 0.0 gi|34101286 zinc finger RNA binding protein [Homo sapiens] 366 e-101 gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo s... 342 7e-94 gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 170 6e-42 gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 170 6e-42 gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 170 6e-42 gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 170 6e-42 gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 129 2e-29 gi|24234747 interleukin enhancer binding factor 2 [Homo sapiens] 101 3e-21 gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 100 1e-20 gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 100 1e-20 gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 94 6e-19 gi|57864582 hornerin [Homo sapiens] 94 7e-19 gi|62122917 filaggrin family member 2 [Homo sapiens] 92 3e-18 gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 90 8e-18 gi|109255251 loricrin [Homo sapiens] 90 8e-18 gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 85 3e-16 gi|56699482 hypothetical protein LOC25940 [Homo sapiens] 83 1e-15 gi|55956899 keratin 9 [Homo sapiens] 83 1e-15 gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 74 6e-13 gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 74 6e-13 gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 74 8e-13 gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 74 8e-13 gi|195972866 keratin 10 [Homo sapiens] 73 1e-12 gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 72 2e-12 >gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo sapiens] Length = 894 Score = 1828 bits (4734), Expect = 0.0 Identities = 894/894 (100%), Positives = 894/894 (100%) Query: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 Query: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP Sbjct: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 Query: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM Sbjct: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 Query: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV Sbjct: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 Query: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT Sbjct: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 Query: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP Sbjct: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 Query: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL Sbjct: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 Query: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE Sbjct: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 Query: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK 540 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK Sbjct: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK 540 Query: 541 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK 600 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK Sbjct: 541 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK 600 Query: 601 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA 660 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA Sbjct: 601 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA 660 Query: 661 NHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGD 720 NHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGD Sbjct: 661 NHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGD 720 Query: 721 NYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHG 780 NYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHG Sbjct: 721 NYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHG 780 Query: 781 QGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGS 840 QGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGS Sbjct: 781 QGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGS 840 Query: 841 GGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR 894 GGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR Sbjct: 841 GGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR 894 >gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo sapiens] Length = 898 Score = 1822 bits (4719), Expect = 0.0 Identities = 894/898 (99%), Positives = 894/898 (99%), Gaps = 4/898 (0%) Query: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 Query: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP Sbjct: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 Query: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM Sbjct: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 Query: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV Sbjct: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 Query: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT Sbjct: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 Query: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP Sbjct: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 Query: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL Sbjct: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 Query: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE Sbjct: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 Query: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE----QGPILTKHGKNPVMELNEKR 536 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE QGPILTKHGKNPVMELNEKR Sbjct: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR 540 Query: 537 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL 596 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL Sbjct: 541 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL 600 Query: 597 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG 656 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG Sbjct: 601 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG 660 Query: 657 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY 716 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY Sbjct: 661 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSY 720 Query: 717 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG 776 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG Sbjct: 721 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG 780 Query: 777 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY 836 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY Sbjct: 781 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY 840 Query: 837 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR 894 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR Sbjct: 841 GGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR 898 >gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo sapiens] Length = 702 Score = 1380 bits (3572), Expect = 0.0 Identities = 688/692 (99%), Positives = 691/692 (99%) Query: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 Query: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP Sbjct: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 Query: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM Sbjct: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 Query: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV Sbjct: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 Query: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT Sbjct: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 Query: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP Sbjct: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 Query: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL Sbjct: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 Query: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE Sbjct: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 Query: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK 540 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK Sbjct: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK 540 Query: 541 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK 600 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK Sbjct: 541 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK 600 Query: 601 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA 660 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA Sbjct: 601 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA 660 Query: 661 NHGGYMNAGAGYGSYGYGGNSATAGYSQFYSN 692 NHGGYMNAGAGYGSYGYGGNSATAGYS F+++ Sbjct: 661 NHGGYMNAGAGYGSYGYGGNSATAGYSDFFTD 692 Score = 30.4 bits (67), Expect = 7.7 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 781 QGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSG-GASYNPGSHGGYGGG 839 +G ++ ++PG G G + E + G GG+ G G G + +HGGY Sbjct: 609 RGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNA 668 Query: 840 SGGGSSYQGKQGGYSQSNYN 859 G SY G G + + Y+ Sbjct: 669 GAGYGSY-GYGGNSATAGYS 687 >gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo sapiens] Length = 690 Score = 1376 bits (3562), Expect = 0.0 Identities = 687/689 (99%), Positives = 688/689 (99%) Query: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 Query: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP Sbjct: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 Query: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM Sbjct: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 Query: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV Sbjct: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 Query: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT Sbjct: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 Query: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP Sbjct: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 Query: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL Sbjct: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 Query: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE Sbjct: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 Query: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK 540 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK Sbjct: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLK 540 Query: 541 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK 600 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK Sbjct: 541 YELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANK 600 Query: 601 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA 660 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA Sbjct: 601 KKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA 660 Query: 661 NHGGYMNAGAGYGSYGYGGNSATAGYSQF 689 NHGGYMNAGAGYGSYGYGGNSATAGY+ F Sbjct: 661 NHGGYMNAGAGYGSYGYGGNSATAGYTGF 689 >gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo sapiens] Length = 706 Score = 1374 bits (3557), Expect = 0.0 Identities = 688/696 (98%), Positives = 691/696 (99%), Gaps = 4/696 (0%) Query: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA Sbjct: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 Query: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP Sbjct: 61 ESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKP 120 Query: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM Sbjct: 121 TTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEM 180 Query: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV Sbjct: 181 EKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRV 240 Query: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT Sbjct: 241 PTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEAT 300 Query: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP Sbjct: 301 DAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIP 360 Query: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL Sbjct: 361 PSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKL 420 Query: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE Sbjct: 421 VSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGE 480 Query: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE----QGPILTKHGKNPVMELNEKR 536 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE QGPILTKHGKNPVMELNEKR Sbjct: 481 DSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKR 540 Query: 537 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL 596 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL Sbjct: 541 RGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLAL 600 Query: 597 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG 656 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG Sbjct: 601 DANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRG 660 Query: 657 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSN 692 FGGANHGGYMNAGAGYGSYGYGGNSATAGYS F+++ Sbjct: 661 FGGANHGGYMNAGAGYGSYGYGGNSATAGYSDFFTD 696 Score = 30.4 bits (67), Expect = 7.7 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 781 QGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSG-GASYNPGSHGGYGGG 839 +G ++ ++PG G G + E + G GG+ G G G + +HGGY Sbjct: 613 RGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNA 672 Query: 840 SGGGSSYQGKQGGYSQSNYN 859 G SY G G + + Y+ Sbjct: 673 GAGYGSY-GYGGNSATAGYS 691 >gi|21361745 spermatid perinuclear RNA binding protein [Homo sapiens] Length = 672 Score = 723 bits (1866), Expect = 0.0 Identities = 398/684 (58%), Positives = 490/684 (71%), Gaps = 51/684 (7%) Query: 1 MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQA 60 MR +R F NDDRHVM KHS++YP+ EELEAVQNMVS E ALK VSDW+DE KG+ + Sbjct: 1 MRSIRSFANDDRHVMVKHSTIYPSPEELEAVQNMVSTVECALKHVSDWLDETNKGTKTEG 60 Query: 61 ESD-NMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEK 119 E++ D E+ SK+ G RTL GVMR+GLVAKGLL+K D+DLELVL+CK+K Sbjct: 61 ETEVKKDEAGENYSKDQGG--------RTLCGVMRIGLVAKGLLIKDDMDLELVLMCKDK 112 Query: 120 PTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREE 179 PT LL+ V DNL IQ+ +TE+KY++ Q V++A+I+I+NTKEP L+L + LTSP++R+E Sbjct: 113 PTETLLNTVKDNLPIQIQKLTEEKYQVEQCVNEASIIIRNTKEPTLTLKVILTSPLIRDE 172 Query: 180 MEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTR 239 +EK GE +S+ DPPD+LDRQKCL ALASLRHAKWFQARANGLKSCVIV+R+LRDLC R Sbjct: 173 LEKK-DGENVSMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNR 231 Query: 240 VPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEA 299 VPTW PL+GWPLEL+CEKSIGT NRP+GAGEALRRV+ECLASGI++P G G++DPCE++ Sbjct: 232 VPTWAPLKGWPLELICEKSIGTCNRPLGAGEALRRVMECLASGILLPGGPGLHDPCERDP 291 Query: 300 TDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQI 359 TDA+ ++ QQ+EDIT SAQHALRL+AFGQ++KVL MDPLPS P + Y+ + Sbjct: 292 TDALSYMTIQQKEDITHSAQHALRLSAFGQIYKVLEMDPLPSSKPFQ-------KYSWSV 344 Query: 360 PPSTTYAITPMKRPMEED-GEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQY 418 + +KRP E+ G++K P+KK K+ +K ++ MNALMRLNQ++PGLQY Sbjct: 345 TDKEGAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQY 404 Query: 419 KLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSK 478 KL+SQ+GPVHAP+FTMSV+VDG ++EASGPSKKTAKLHVAVKVLQ MG PTG + Sbjct: 405 KLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECM 464 Query: 479 GEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAE---QGPILTKHGKNPVMELNEK 535 D + E+K V+ + +T ++ + +T E QGPILT GKNPVMELNEK Sbjct: 465 SSDEKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEK 521 Query: 536 RRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595 RRGLKYELISETGGSHDKRFVMEVEVDGQKF+GAG NKKVAKA AALAALEKLF P A Sbjct: 522 RRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLF-SGPNA 580 Query: 596 LDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGR 655 AN KK+ +P G A +RGRGRG RG Sbjct: 581 --ANNKKKKIIPQAKGVVNTAVS---------------AAVQAVRGRGRGTLTRG----- 618 Query: 656 GFGGANHG-GYMNAGAGYGS-YGY 677 F GA GY+ GYG+ YGY Sbjct: 619 AFVGATAAPGYI--APGYGTPYGY 640 >gi|34101286 zinc finger RNA binding protein [Homo sapiens] Length = 1074 Score = 366 bits (940), Expect = e-101 Identities = 186/334 (55%), Positives = 243/334 (72%), Gaps = 21/334 (6%) Query: 9 NDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQAESDNMDVP 68 +DDR+VM KH+++YPT+EEL+AVQ +VS TERALK VSD + E EK +++ Sbjct: 722 SDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDSLSEHEKNKNKEG-------- 773 Query: 69 PEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKV 128 DD KEG + R L+GV+RVG++AKGLLL+GD ++ LVLLC EKP+ LL ++ Sbjct: 774 --DDKKEGGKD-------RALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKTLLSRI 824 Query: 129 ADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGET 188 A+NL QLA ++ +KY+I +V +AAI++ + EP + +TI LTSP++REE + G+ Sbjct: 825 AENLPKQLAVISPEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIREE--NMREGDV 882 Query: 189 LS--VNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPL 246 S V DPPDVLDRQKCL ALA+LRHAKWFQARANGL+SCVI+IR+LRDLC RVPTW Sbjct: 883 TSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDF 942 Query: 247 RGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHL 306 W +ELL EK+I +A+ P G+ALRRV EC++SGI++ G+ DPCEK+ D + + Sbjct: 943 PSWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATM 1002 Query: 307 DRQQREDITQSAQHALRLAAFGQLHKVLGMDPLP 340 QQREDIT SAQ ALRL AF Q+HKVLGMDPLP Sbjct: 1003 TDQQREDITSSAQFALRLLAFRQIHKVLGMDPLP 1036 >gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo sapiens] Length = 939 Score = 342 bits (878), Expect = 7e-94 Identities = 177/334 (52%), Positives = 235/334 (70%), Gaps = 17/334 (5%) Query: 9 NDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQAESDNMDVP 68 +DDRHVM KH+++YPT++EL AVQ VSH ERALK VSD + E+++G E+ V Sbjct: 588 SDDRHVMCKHATIYPTEQELLAVQRAVSHAERALKLVSDTLAEEDRGRREEEGDKRSSVA 647 Query: 69 PEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKV 128 P+ TR L+GVMRVG++AKGLLL+GD ++ L LLC EKPT +LL ++ Sbjct: 648 PQ---------------TRVLKGVMRVGILAKGLLLRGDRNVRLALLCSEKPTHSLLRRI 692 Query: 129 ADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGET 188 A L QL VTED+YE+ S +A IVI + +EP + +TI +TSP++RE+ E Sbjct: 693 AQQLPRQLQMVTEDEYEV-SSDPEANIVISSCEEPRMQVTISVTSPLMREDPSTDPGVEE 751 Query: 189 LSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRG 248 D DVL +KCL +LA+LRHA+WFQARA+GL+ CVIVIRVLRDLC RVPTWG L Sbjct: 752 PQA-DAGDVLSPKKCLESLAALRHARWFQARASGLQPCVIVIRVLRDLCRRVPTWGALPA 810 Query: 249 WPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDR 308 W +ELL EK++ +A P+G G+A+RRVLEC+A+G ++ DG G+ DPCE++ TDA+ + Sbjct: 811 WAMELLVEKAVSSAAGPLGPGDAVRRVLECVATGTLLTDGPGLQDPCERDQTDALEPMTL 870 Query: 309 QQREDITQSAQHALRLAAFGQLHKVLGMDPLPSK 342 Q+RED+T SAQHALR+ AF Q HKVLGMD LP + Sbjct: 871 QEREDVTASAQHALRMLAFRQTHKVLGMDLLPPR 904 >gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo sapiens] Length = 674 Score = 170 bits (430), Expect = 6e-42 Identities = 115/271 (42%), Positives = 150/271 (55%), Gaps = 39/271 (14%) Query: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430 KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP Sbjct: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107 Query: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAE-----GRDSSKGEDSAE 484 +F MSVEV+G FE SGP+KK AKLH A K L+ + P +E GR S D Sbjct: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167 Query: 485 E---------------TEAKPAVVAPAPVVEAVSTPS----AAFPSDATAEQGPILT--- 522 + +A+P + ++ S+ +A P A+ Q P+ Sbjct: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227 Query: 523 ---KHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 579 GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA Sbjct: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287 Query: 580 AALAALEKLFPDTPLALDANKKKRAPVPVRG 610 AA +AL +F L LD R P+P G Sbjct: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314 >gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo sapiens] Length = 714 Score = 170 bits (430), Expect = 6e-42 Identities = 115/271 (42%), Positives = 150/271 (55%), Gaps = 39/271 (14%) Query: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430 KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP Sbjct: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107 Query: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAE-----GRDSSKGEDSAE 484 +F MSVEV+G FE SGP+KK AKLH A K L+ + P +E GR S D Sbjct: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167 Query: 485 E---------------TEAKPAVVAPAPVVEAVSTPS----AAFPSDATAEQGPILT--- 522 + +A+P + ++ S+ +A P A+ Q P+ Sbjct: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227 Query: 523 ---KHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 579 GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA Sbjct: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287 Query: 580 AALAALEKLFPDTPLALDANKKKRAPVPVRG 610 AA +AL +F L LD R P+P G Sbjct: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314 >gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo sapiens] Length = 741 Score = 170 bits (430), Expect = 6e-42 Identities = 115/271 (42%), Positives = 150/271 (55%), Gaps = 39/271 (14%) Query: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430 KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP Sbjct: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107 Query: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAE-----GRDSSKGEDSAE 484 +F MSVEV+G FE SGP+KK AKLH A K L+ + P +E GR S D Sbjct: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167 Query: 485 E---------------TEAKPAVVAPAPVVEAVSTPS----AAFPSDATAEQGPILT--- 522 + +A+P + ++ S+ +A P A+ Q P+ Sbjct: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227 Query: 523 ---KHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 579 GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA Sbjct: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287 Query: 580 AALAALEKLFPDTPLALDANKKKRAPVPVRG 610 AA +AL +F L LD R P+P G Sbjct: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314 >gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo sapiens] Length = 701 Score = 170 bits (430), Expect = 6e-42 Identities = 115/271 (42%), Positives = 150/271 (55%), Gaps = 39/271 (14%) Query: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430 KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP Sbjct: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107 Query: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAE-----GRDSSKGEDSAE 484 +F MSVEV+G FE SGP+KK AKLH A K L+ + P +E GR S D Sbjct: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167 Query: 485 E---------------TEAKPAVVAPAPVVEAVSTPS----AAFPSDATAEQGPILT--- 522 + +A+P + ++ S+ +A P A+ Q P+ Sbjct: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227 Query: 523 ---KHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 579 GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA Sbjct: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287 Query: 580 AALAALEKLFPDTPLALDANKKKRAPVPVRG 610 AA +AL +F L LD R P+P G Sbjct: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314 >gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] Length = 739 Score = 129 bits (323), Expect = 2e-29 Identities = 100/303 (33%), Positives = 147/303 (48%), Gaps = 36/303 (11%) Query: 337 DPLPSKMPKKPKNENPVDYTVQIPPSTTYAI-----TPMKRPMEEDGEEKSPSKKKKKIQ 391 D L + + +N N + + PPS A KRP+EE K + + Sbjct: 60 DTLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNG--GHLCKLQLVW 117 Query: 392 KKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKK 451 KK + P+ NAL++L++L+PGLQY+ VSQTGPVHAP+F ++VEV+G +FE +GP+KK Sbjct: 118 KKLSWSVAPK--NALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKK 175 Query: 452 TAKLHVAVKVLQD-MGLPTG-----AEGRDSSKGEDSAEETEAKPAVV-------APAPV 498 AK+ A L+ + P A G G D + P + AP P Sbjct: 176 KAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPG 235 Query: 499 VEAVSTPSAAFPSDATAEQ----------GPI----LTKHGKNPVMELNEKRRGLKYELI 544 + AA S A + GP +NPV+ LN R GL+Y + Sbjct: 236 LAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCL 295 Query: 545 SETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRA 604 +E + FVM V VDG+ F+G+G +KK+A+ AA AAL++LF + +R Sbjct: 296 AEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRT 355 Query: 605 PVP 607 P+P Sbjct: 356 PMP 358 Score = 55.5 bits (132), Expect = 2e-07 Identities = 44/124 (35%), Positives = 60/124 (48%), Gaps = 11/124 (8%) Query: 526 KNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 585 KN +++L+E R GL+Y +S+TG H F + VEV+G F+G G KK AK AA AL Sbjct: 127 KNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELAL 186 Query: 586 EKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPP---PNLRGR 642 + F P A A+ + + GGP + + E PP P L G Sbjct: 187 -RSFVQFPNACQAH------LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAG- 238 Query: 643 GRGG 646 GR G Sbjct: 239 GRPG 242 >gi|24234747 interleukin enhancer binding factor 2 [Homo sapiens] Length = 390 Score = 101 bits (252), Expect = 3e-21 Identities = 92/322 (28%), Positives = 148/322 (45%), Gaps = 56/322 (17%) Query: 92 VMRVGLVAKGLLLKGDLDLELVLLCKEKPT----TALLDKVADNLAIQ-----LAAVT-E 141 V +VG KG + G +LV++ K PT AL +KV ++L Q L +T E Sbjct: 102 VRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNE 161 Query: 142 DKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQ 201 +EI S DA + I T PP L DP LD + Sbjct: 162 TGFEISSS--DATVKILITTVPP-----------------------NLRKLDPELHLDIK 196 Query: 202 KCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLELLCEKSI-- 259 +ALA++RHA+WF+ A+ + ++IR+L+DL R P + PL W L+LL ++ Sbjct: 197 VLQSALAAIRHARWFEENASQ-STVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMN 255 Query: 260 GTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQ 319 +P+ A RR L+ LA+G+ +P GI DPCE + +Q++ + +AQ Sbjct: 256 NPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQ 315 Query: 320 HALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGE 379 +R+ + G K+LG + S + + + V +TP ++ E+ Sbjct: 316 TLVRILSHGGFRKILGQEGDASYLASEISTWDGV------------IVTPSEKAYEK--- 360 Query: 380 EKSPSKKKKKIQKKEEKAEPPQ 401 P +KK+ +++E EPPQ Sbjct: 361 ---PPEKKEGEEEEENTEEPPQ 379 >gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] Length = 589 Score = 99.8 bits (247), Expect = 1e-20 Identities = 78/232 (33%), Positives = 95/232 (40%), Gaps = 33/232 (14%) Query: 631 NEVPPPPNLRGRGRGGSIRGRGRG--RGFGGANHGGYMNAGAGYGSYGYGGNSATAGY-S 687 N+ P R GG RGRG G RG+ G G G GYGG+ + GY Sbjct: 374 NQCNEPRPEDSRPSGGDFRGRGYGGERGYRG-------RGGRGGDRGGYGGDRSGGGYGG 426 Query: 688 QFYSNGGHSGNASGGGGGGGGGSSGY----GSYYQGD---NYNSPVPPKHAGKKQPHGGQ 740 S GG+SG+ SGGG GG GY G Y GD Y + G + +GG Sbjct: 427 DRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGD 486 Query: 741 QKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGG--GGG 798 + YG + G + Y G + GY +G Y S GG GGG Sbjct: 487 RGGGYGGDRGGYGGDRGGYG-----------GDRGGYGGDRGGYGGDRSRGGYGGDRGGG 535 Query: 799 SDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQ 850 S Y + Y G RSGG G G Y G GGYGG GG + Y+ Q Sbjct: 536 SGYGGDRSGGYGGD--RSGGGYGGDRGGGYG-GDRGGYGGKMGGRNDYRNDQ 584 Score = 64.7 bits (156), Expect = 4e-10 Identities = 61/230 (26%), Positives = 93/230 (40%), Gaps = 40/230 (17%) Query: 660 ANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQG 719 ++ G Y +G SY GN + GY Q ++ +SG G SGY SY G Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQ--ASQSYSGYGQTTDSSYGQNYSGYSSY--G 57 Query: 720 DNYNSPVPPKHAGKKQPHGG---QQKPSYGSGYQSHQGQQQ-------------SYNQSP 763 +Y+ Q +GG Q++ SY ++QGQQQ SY+Q Sbjct: 58 QSYS-----------QSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD 106 Query: 764 YSNYGPPQGKQKGYNHGQGSY----SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN 819 Y +Q GY+ QGSY +Y ++S S ++ +++ R + Sbjct: 107 YGQQ-DSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVS 165 Query: 820 SYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG 869 YG N G G GGG G G + +G + S+ G +N+ G Sbjct: 166 RYGED----NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211 Score = 58.2 bits (139), Expect = 3e-08 Identities = 51/177 (28%), Positives = 74/177 (41%), Gaps = 15/177 (8%) Query: 659 GANHGGYMNAGAGYG-SYGYGGNSATAGYSQF-YSNGGHSGNA-SGGGGGGGGGSSGYGS 715 G N+ GY + G Y SYG N + YSQ Y+N G N S G GG S Sbjct: 47 GQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPD 106 Query: 716 YYQGDNYNSPVP-PKHAGK--KQPHGGQQKPSYGSGYQSHQGQQQSYN------QSPYSN 766 Y Q D+Y+ +H G +Q + QQ SY QS+ Q+++Y+ + S Sbjct: 107 YGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSR 166 Query: 767 YGPPQ---GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNS 820 YG G +G G+G Y G GG +++ + G R+ +S Sbjct: 167 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADS 223 Score = 49.3 bits (116), Expect = 2e-05 Identities = 49/153 (32%), Positives = 65/153 (42%), Gaps = 23/153 (15%) Query: 744 SYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNY 803 S Y G+QQSY S YG P G Q +GQ S SYS G G +D +Y Sbjct: 2 SDSGSYGQSGGEQQSY-----STYGNP-GSQ---GYGQASQSYS------GYGQTTDSSY 46 Query: 804 ESKFNYSGSGGRSGGNSYG----SGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYN 859 ++ S G+S SYG +SY+ + G SS G QGG + S Y+ Sbjct: 47 GQNYSGYSSYGQSYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS--GSQGGRAPS-YD 103 Query: 860 SPGSGQNYS-GPPSSYQSSQGGYGRNADHSMNY 891 P GQ S S Y QG Y +++ + Sbjct: 104 QPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQH 136 Score = 43.5 bits (101), Expect = 9e-04 Identities = 38/88 (43%), Positives = 43/88 (48%), Gaps = 18/88 (20%) Query: 810 SGSGGRSGGN--SYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 867 SGS G+SGG SY + G NPGS G YG S S Y G + S+Y GQNY Sbjct: 4 SGSYGQSGGEQQSYSTYG---NPGSQG-YGQASQSYSGY----GQTTDSSY-----GQNY 50 Query: 868 SGPPS---SYQSSQGGYGRNADHSMNYQ 892 SG S SY S GGY S + Q Sbjct: 51 SGYSSYGQSYSQSYGGYENQKQSSYSQQ 78 >gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] Length = 592 Score = 99.8 bits (247), Expect = 1e-20 Identities = 78/232 (33%), Positives = 95/232 (40%), Gaps = 33/232 (14%) Query: 631 NEVPPPPNLRGRGRGGSIRGRGRG--RGFGGANHGGYMNAGAGYGSYGYGGNSATAGY-S 687 N+ P R GG RGRG G RG+ G G G GYGG+ + GY Sbjct: 377 NQCNEPRPEDSRPSGGDFRGRGYGGERGYRG-------RGGRGGDRGGYGGDRSGGGYGG 429 Query: 688 QFYSNGGHSGNASGGGGGGGGGSSGY----GSYYQGD---NYNSPVPPKHAGKKQPHGGQ 740 S GG+SG+ SGGG GG GY G Y GD Y + G + +GG Sbjct: 430 DRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGD 489 Query: 741 QKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGG--GGG 798 + YG + G + Y G + GY +G Y S GG GGG Sbjct: 490 RGGGYGGDRGGYGGDRGGYG-----------GDRGGYGGDRGGYGGDRSRGGYGGDRGGG 538 Query: 799 SDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQ 850 S Y + Y G RSGG G G Y G GGYGG GG + Y+ Q Sbjct: 539 SGYGGDRSGGYGGD--RSGGGYGGDRGGGYG-GDRGGYGGKMGGRNDYRNDQ 587 Score = 67.8 bits (164), Expect = 4e-11 Identities = 61/222 (27%), Positives = 93/222 (41%), Gaps = 21/222 (9%) Query: 660 ANHGGYMNAGAGYGSYGYGGNSATAGY---SQFYSNGGHSGNASGGGGGGGGGS-----S 711 ++ G Y +G SY GN + GY SQ YS G + ++S G G S S Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQS 61 Query: 712 GYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQ 771 GY Y G Y + ++ + + GQQ+ SG Q G+ SY+Q Y Sbjct: 62 GYSQSYGG--YENQKQSSYSQQPYNNQGQQQNMESSGSQG--GRAPSYDQPDYGQQDS-Y 116 Query: 772 GKQKGYNHGQGSY----SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGAS 827 +Q GY+ QGSY +Y ++S S ++ +++ R + YG Sbjct: 117 DQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGED--- 173 Query: 828 YNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG 869 N G G GGG G G + +G + S+ G +N+ G Sbjct: 174 -NRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214 Score = 60.8 bits (146), Expect = 5e-09 Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 23/191 (12%) Query: 656 GFGGANHGGYMNAGAGYGSYG---------YGG--NSATAGYSQF-YSNGGHSGN-ASGG 702 G+G Y +GY SYG YGG N + YSQ Y+N G N S G Sbjct: 37 GYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSG 96 Query: 703 GGGGGGGSSGYGSYYQGDNYNSPVP-PKHAGK--KQPHGGQQKPSYGSGYQSHQGQQQSY 759 GG S Y Q D+Y+ +H G +Q + QQ SY QS+ Q+++Y Sbjct: 97 SQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENY 156 Query: 760 NQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN 819 + + ++ +G+ + Y S G GG D + S G R G Sbjct: 157 SHHTQDD------RRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK 210 Query: 820 SYGSGGASYNP 830 ++G G Y P Sbjct: 211 NFG-GHRDYGP 220 Score = 50.1 bits (118), Expect = 9e-06 Identities = 47/150 (31%), Positives = 63/150 (42%), Gaps = 14/150 (9%) Query: 744 SYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNY 803 S Y G+QQSY S YG P G Q +GQ S SYS + G +Y+ Sbjct: 2 SDSGSYGQSGGEQQSY-----STYGNP-GSQ---GYGQASQSYSGYGQTTDSSYGQNYSG 52 Query: 804 ESKFNYSGSG-GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPG 862 S + S SG +S G +SY+ + G SS G QGG + S Y+ P Sbjct: 53 YSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESS--GSQGGRAPS-YDQPD 109 Query: 863 SGQNYS-GPPSSYQSSQGGYGRNADHSMNY 891 GQ S S Y QG Y +++ + Sbjct: 110 YGQQDSYDQQSGYDQHQGSYDEQSNYDQQH 139 Score = 48.9 bits (115), Expect = 2e-05 Identities = 50/194 (25%), Positives = 63/194 (32%), Gaps = 30/194 (15%) Query: 700 SGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHG-GQQKPSYGSGYQSHQGQQQS 758 SG G GG Y +Y G G GQ SY SGY Sbjct: 4 SGSYGQSGGEQQSYSTY---------------GNPGSQGYGQASQSY-SGYGQTTDSSYG 47 Query: 759 YNQSPYSNYGPPQGKQKGYNHGQGSY---SYSNSYNSPGGGGGSDYNYESKFNYSGSGGR 815 N S YS+YG Q GY+ G Y S+ P G N ES + G Sbjct: 48 QNYSGYSSYGQ---SQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS 104 Query: 816 SGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYS------- 868 YG + + + G S+Y + YSQ+ + +NYS Sbjct: 105 YDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDR 164 Query: 869 GPPSSYQSSQGGYG 882 S Y GYG Sbjct: 165 RDVSRYGEDNRGYG 178 Score = 43.9 bits (102), Expect = 7e-04 Identities = 70/303 (23%), Positives = 96/303 (31%), Gaps = 59/303 (19%) Query: 641 GRGRGGSIR-GRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNA 699 GRGRGG + GRG G G + GG+ N G G+ YG ++ + S+ + Sbjct: 184 GRGRGGYDKDGRGPMTGSSGGDRGGFKNFG-GHRDYGPRTDADSE------SDNSDNNTI 236 Query: 700 SGGGGGGGGGSSGYGSYYQ-----------GDNYNSPVPPKHAGKKQPHGG---QQKPSY 745 G G G + G +++ G + K GK + PS Sbjct: 237 FVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSA 296 Query: 746 GSGYQSHQGQQQSYN--QSPYSNYGPP---QGKQKGYNHGQGSYSYSNSYNSPGGG---- 796 + G++ N + ++ P G G G+G Y + GG Sbjct: 297 KAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 356 Query: 797 ---------GGSDYNYESKFNYSG---------SGGRSGGNSYGS----GGASYNPGSHG 834 G ++ + N SGG G YG G G G Sbjct: 357 DWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRG 416 Query: 835 GYGGGSGGG------SSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHS 888 GYGG GG SS G G S Y SG Y G G G D Sbjct: 417 GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG 476 Query: 889 MNY 891 Y Sbjct: 477 GGY 479 >gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma) [Homo sapiens] Length = 526 Score = 94.0 bits (232), Expect = 6e-19 Identities = 83/263 (31%), Positives = 103/263 (39%), Gaps = 56/263 (21%) Query: 657 FGGANHGGYMNA----GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSG 712 +G ++ GY + G G SY G S GY + G+ G GG G S Sbjct: 33 YGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGY-----GSTGGYGSSQSS 87 Query: 713 YGSYYQGDNY----NSPVPPKHAGKK----------QPHGGQ--QKPSYGSGYQSHQGQQ 756 SY Q +Y P P +G QP G Q+PSYG QS+ GQQ Sbjct: 88 QSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSY-GQQ 146 Query: 757 QSYNQSPYSNYGPPQG--KQKGYNH---------GQGSYSYSNSYNSPGGGGGSDYNYES 805 QSYN PPQG +Q YN G G+Y S S GGG G Y + Sbjct: 147 QSYN--------PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQD 198 Query: 806 KFNYSGSGG----------RSG-GNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS 854 + GSGG R G G G GG YN S G G GGG +G GG Sbjct: 199 QSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSD 258 Query: 855 QSNYNSPGSGQNYSGPPSSYQSS 877 + +N G ++ S Q + Sbjct: 259 RGGFNKFGGPRDQGSRHDSEQDN 281 Score = 93.2 bits (230), Expect = 1e-18 Identities = 84/250 (33%), Positives = 104/250 (41%), Gaps = 56/250 (22%) Query: 656 GFGGANHGGY-MNAGAGYGSY----GYGGNSATAGYSQFYSNGGHSGNASGGGGGG---- 706 G+G +++ Y + GYG+ GYG +T GY S+ G S G G Sbjct: 49 GYGQSSYSSYGQSQNTGYGTQSTPQGYG---STGGYGSSQSSQSSYGQQSSYPGYGQQPA 105 Query: 707 -GGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYS 765 S YGS Q +Y P ++ +QP G Q+ SY GQQQSYN Sbjct: 106 PSSTSGSYGSSSQSSSYGQPQSGSYS--QQPSYGGQQQSY--------GQQQSYN----- 150 Query: 766 NYGPPQGKQKGYNHGQGSYSYSNSYNSP---GGGGGSDYNYESKFNYSGSGGRSGG---- 818 PPQG Y N YNS GGGGG NY + SGG SGG Sbjct: 151 ---PPQG-----------YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGN 196 Query: 819 --NSYGSGGASYNPGSHGGYG-GGSGGGSSYQGKQGGYSQSN--YNSPGSGQNYSGPPSS 873 S G G Y GG G GGSGGG G GGY++S+ Y G G G Sbjct: 197 QDQSGGGGSGGYGQQDRGGRGRGGSGGGGG--GGGGGYNRSSGGYEPRGRGGGRGGRGGM 254 Query: 874 YQSSQGGYGR 883 S +GG+ + Sbjct: 255 GGSDRGGFNK 264 Score = 68.2 bits (165), Expect = 3e-11 Identities = 76/234 (32%), Positives = 88/234 (37%), Gaps = 51/234 (21%) Query: 668 AGAGYGSY------GYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDN 721 A YG+Y GY S+ Q YS S + SG G S Y SY Q N Sbjct: 10 ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYG------QSSYSSYGQSQN 63 Query: 722 YNSPVPPKHAGKKQPHGGQQKPS-YGS--GYQSHQGQQQSYNQ-SPYSNYGPPQGKQKGY 777 +G Q P YGS GY S Q Q SY Q S Y YG Q Sbjct: 64 TG-------------YGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQ-QPAPSST 109 Query: 778 NHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYG 837 + GS S S+SY P G +Y + +Y G SYG SYNP GYG Sbjct: 110 SGSYGSSSQSSSYGQPQSG-----SYSQQPSYGGQQ-----QSYGQQ-QSYNPPQ--GYG 156 Query: 838 GGSGGGSSYQGKQGGYSQSNY--------NSPGSGQNYSGPPSSYQSSQGGYGR 883 + SS G GG NY + GSG Y S GGYG+ Sbjct: 157 QQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210 Score = 62.8 bits (151), Expect = 1e-09 Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 72/317 (22%) Query: 610 GGPKFAAKPHNPGFGMGGPMHNEVPP--PPNLRGRGRGGSIRGRGRGRGFGGANHGGYMN 667 G P+ + P +G + + PP G+ + G G G GG N+G + Sbjct: 123 GQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQS 182 Query: 668 A-------GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGG----SSGYGSY 716 + G GYG+ G + GY Q G G + GGGGGGGGG S GY Sbjct: 183 SMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPR 242 Query: 717 YQG--------------DNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQS 762 +G +N P+ G + H +Q S + QG ++ Sbjct: 243 GRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSR--HDSEQDNS-DNNTIFVQGLGENVTIE 299 Query: 763 PYSNY-------------GPPQ-----GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYE 804 ++Y G P ++ G G+ + S+ + P D+ ++ Sbjct: 300 SVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD---DPPSAKAAIDW-FD 355 Query: 805 SKFNYSGSG------------GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGG 852 K +SG+ R GGN G G P GGYGGG GG G +GG Sbjct: 356 GK-EFSGNPIKVSFATRRADFNRGGGNGRGGRGRG-GPMGRGGYGGGGSGG----GGRGG 409 Query: 853 YSQSNYNSPGSGQNYSG 869 + G GQ +G Sbjct: 410 FPSG--GGGGGGQQRAG 424 Score = 61.2 bits (147), Expect = 4e-09 Identities = 63/240 (26%), Positives = 86/240 (35%), Gaps = 43/240 (17%) Query: 628 PMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYS 687 P + + P P + GS + +G G Y + G G + Sbjct: 98 PGYGQQPAPSST-----SGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPP 152 Query: 688 QFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGS 747 Q Y ++SGGGGGGGGG G+Y Q + S GG YG+ Sbjct: 153 QGYGQQNQYNSSSGGGGGGGGG----GNYGQDQSSMS------------SGGGSGGGYGN 196 Query: 748 GYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYES-K 806 QS G Y Q G+ +G + G GGGGG YN S Sbjct: 197 QDQSGGGGSGGYGQQDRG------GRGRGGSGG------------GGGGGGGGYNRSSGG 238 Query: 807 FNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQN 866 + G GG GG G GG+ + G +GG GS + +Q + G G+N Sbjct: 239 YEPRGRGGGRGGRG-GMGGS--DRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGEN 295 Score = 53.9 bits (128), Expect = 6e-07 Identities = 46/142 (32%), Positives = 56/142 (39%), Gaps = 28/142 (19%) Query: 759 YNQSPYSNYG-----PPQG--KQKGYNHGQGSYS-YSNSYNSPGGGGGSDYNYESKFNYS 810 Y Q +YG P QG +Q +GQ SYS YS S ++ G G S +Y Sbjct: 6 YTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSY------- 58 Query: 811 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSY--QGKQGGYSQ--------SNYNS 860 G+S YG+ GS GGYG SSY Q GY Q +Y S Sbjct: 59 ---GQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGS 115 Query: 861 PGSGQNYSGPPSSYQSSQGGYG 882 +Y P S S Q YG Sbjct: 116 SSQSSSYGQPQSGSYSQQPSYG 137 Score = 53.1 bits (126), Expect = 1e-06 Identities = 55/189 (29%), Positives = 63/189 (33%), Gaps = 56/189 (29%) Query: 651 RGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGS 710 RG G G GG GG M G G YG GG S GG G GGGGGGG Sbjct: 377 RGGGNGRGGRGRGGPM----GRGGYGGGG-----------SGGGGRGGFPSGGGGGGG-- 419 Query: 711 SGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPP 770 + ++ P P + Q P G P Sbjct: 420 -----QQRAGDWKCPNP---------------TCENMNFSWRNECNQCKAPKPDGPGGGP 459 Query: 771 QGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNP 830 G G N+G + GG GG D + Y G GG GG G GG Sbjct: 460 GGSHMGGNYGD---------DRRGGRGGYD-----RGGYRGRGGDRGGFRGGRGG----- 500 Query: 831 GSHGGYGGG 839 G GG+G G Sbjct: 501 GDRGGFGPG 509 Score = 52.4 bits (124), Expect = 2e-06 Identities = 63/188 (33%), Positives = 70/188 (37%), Gaps = 54/188 (28%) Query: 746 GSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSN----------------S 789 G GY Q Q Y Q YS Y Q G G SYS+ Sbjct: 22 GQGYS--QQSSQPYGQQSYSGYS-----QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQG 74 Query: 790 YNSPGGGGG-----SDYNYESKF----------NYSGS-GGRSGGNSYG---SGGASYNP 830 Y S GG G S Y +S + + SGS G S +SYG SG S P Sbjct: 75 YGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQP 134 Query: 831 GSHGGYGGGSGGGSSYQGKQGGYSQSNYNSP-------GSGQNYSGPPSSYQS---SQGG 880 S+GG G SY QG Q+ YNS G G NY SS S S GG Sbjct: 135 -SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGG 193 Query: 881 YGRNADHS 888 YG N D S Sbjct: 194 YG-NQDQS 200 Score = 48.9 bits (115), Expect = 2e-05 Identities = 47/171 (27%), Positives = 62/171 (36%), Gaps = 38/171 (22%) Query: 697 GNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQ 756 G +G GG G GG G G Y G + GG + + SG GQQ Sbjct: 378 GGGNGRGGRGRGGPMGRGGYGGGGS----------------GGGGRGGFPSGGGGGGGQQ 421 Query: 757 QSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNS-----PGGGGGSDYNYESKFNYSG 811 ++ ++ P + N +S+ N N P G GG NY G Sbjct: 422 RA------GDWKCPNPTCENMN-----FSWRNECNQCKAPKPDGPGGGPGGSHMGGNY-G 469 Query: 812 SGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPG 862 R G Y GG G GG+ GG GGG +GG+ +S G Sbjct: 470 DDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGD-----RGGFGPGKMDSRG 515 Score = 39.3 bits (90), Expect = 0.017 Identities = 28/88 (31%), Positives = 36/88 (40%), Gaps = 5/88 (5%) Query: 808 NYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQN- 866 +Y+ +S G G Y+ S YG S G S GY QS+Y+S G QN Sbjct: 5 DYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNT 64 Query: 867 ---YSGPPSSYQSSQGGYGRNADHSMNY 891 P Y S GGYG + +Y Sbjct: 65 GYGTQSTPQGY-GSTGGYGSSQSSQSSY 91 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 93.6 bits (231), Expect = 7e-19 Identities = 89/316 (28%), Positives = 132/316 (41%), Gaps = 57/316 (18%) Query: 622 GFGMGGPMHNEVPPPPNLR-GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGN 680 G G G + P P R G G G S G G G ++ G +G+G+ S G G Sbjct: 1935 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSS-GLGHR 1993 Query: 681 SA----TAGYSQFYSNGGHS------GNASGGG------GGGGGGSSGYGSYYQGDNYNS 724 + ++GY Q S+ GHS G+ASG G G SS +G + G + +S Sbjct: 1994 ESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 2053 Query: 725 PVPPKHAGKKQP-------HGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGY 777 + +G Q G +Q PSYG + S G+ S Q +GP G+ G+ Sbjct: 2054 GYGRQGSGSGQSPGHGQRGSGSRQSPSYGR-HGSGSGRSSSSGQ-----HGPGLGESSGF 2107 Query: 778 NHGQGSYSYSNSYNSPGGGGGSDYNY----------------------ESKFNYSGSGGR 815 H + S S+SY+ G G G Y S++ GSG R Sbjct: 2108 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSR 2167 Query: 816 -SGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSY 874 S G+ G+ ++P S G +G GSG SS+ Q G +S G ++ SG S + Sbjct: 2168 QSSGHGRQGSGSGHSP-SRGRHGSGSGHSSSH--GQHGSGSGRSSSRGPYESRSGHSSVF 2224 Query: 875 QSSQGGYGRNADHSMN 890 + G G ++ +S + Sbjct: 2225 GQHESGSGHSSAYSQH 2240 Score = 92.0 bits (227), Expect = 2e-18 Identities = 80/289 (27%), Positives = 117/289 (40%), Gaps = 28/289 (9%) Query: 618 PHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGAN---------HGGYMNA 668 P+ G G + ++ G G+ GS G G G+ HG Sbjct: 573 PYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQ 632 Query: 669 GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPP 728 + +G +G G+S ++ Y Q S G S + G G G SS YG + G ++S Sbjct: 633 SSSHGQHG-SGSSQSSRYGQQGSGSGQSPSR-GRHGSDFGHSSSYGQHGSGSGWSS---- 686 Query: 729 KHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQ----SPYSNYGPPQGKQKGYNHGQGSY 784 PHG S G G++S GQ Y+Q S +S+ G + G + + Sbjct: 687 ----SNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQH 742 Query: 785 SYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGS 844 S+ +S G GS + S GSG + G +S + SHG +G G+ S Sbjct: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSS 802 Query: 845 S---YQGKQGGYSQSNYNSPGSGQNYS--GPPSSYQSSQGGYGRNADHS 888 S Y+ G S + GSGQ YS G S + SSQG +G + S Sbjct: 803 SCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQS 851 Score = 90.9 bits (224), Expect = 5e-18 Identities = 89/324 (27%), Positives = 130/324 (40%), Gaps = 52/324 (16%) Query: 611 GPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGA 670 G +A H+ G G + P RG G G S G GFG ++ G +G+ Sbjct: 401 GQHESASRHSSGRGQHSSGSGQ-SPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGS 459 Query: 671 GYGSYGYGGNSATAGYSQFYS-NGGHSGNASGGG---------------GGGGGGSSGYG 714 GY S G+G + +++ +S Y+ +G SG++SG G G G SS YG Sbjct: 460 GYSS-GFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYG 518 Query: 715 SYYQGDNYN------------SPVPPK---HAGKKQ-----PHGGQQKPSYGSGYQSHQG 754 + G + SP P + +G +Q PHG YGSG S +G Sbjct: 519 QHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHG------YGSGRSSSRG 572 Query: 755 QQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSG--S 812 +S S +S+ Q + G + G G + S+ ++S G GS S G S Sbjct: 573 PYES--GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATS 630 Query: 813 GGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYS---G 869 G S +GSG + + G G G G G+S S+Y GSG +S G Sbjct: 631 GQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHS-SSYGQHGSGSGWSSSNG 689 Query: 870 PPSSYQSSQGGYGRNADHSMNYQY 893 P S G+G + + Y Sbjct: 690 PHGSVSGQSSGFGHKSGSGQSSGY 713 Score = 89.0 bits (219), Expect = 2e-17 Identities = 95/336 (28%), Positives = 138/336 (41%), Gaps = 73/336 (21%) Query: 622 GFGMGGPMHNEVPPPPNLR---GRGRGGSIRGRGRGRGFG--------GANHG---GYMN 667 G G G + P P R G G+ S G G G+ G++H G+ Sbjct: 1465 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRE 1524 Query: 668 AGAGYGSYGYGGNSATAGYSQFYS-NGGHSGNASGGG--GGGGGGSSGYGSYYQGDNYNS 724 + +G S GYG + +++G+S + +G SG +S G G G SS +G + G + +S Sbjct: 1525 SRSGQSS-GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 1583 Query: 725 PVPPKHAGKKQP-------HGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGY 777 + +G Q G +Q PSYG + S G+ S Q +G G+ G+ Sbjct: 1584 GYGRQGSGSGQSPGHGQRGSGSRQSPSYGR-HGSGSGRSSSSGQ-----HGSGLGESSGF 1637 Query: 778 NHGQGSYSYSNSYNSPGGGGGSDYNY----------------------ESKFNYSGSGGR 815 H + S S+SY+ G G G Y S++ GSG R Sbjct: 1638 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSR 1697 Query: 816 --SGGNSYGSG-GASYNPG----------SHGGYGGGSGGGSS---YQGKQGGYSQSNYN 859 SG GSG G S + G SHG +G GSG SS Y+ + G S + Sbjct: 1698 QSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQH 1757 Query: 860 SPGSGQN--YS--GPPSSYQSSQGGYGRNADHSMNY 891 GSG + YS G S + SQG +G + S + Sbjct: 1758 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1793 Score = 89.0 bits (219), Expect = 2e-17 Identities = 86/301 (28%), Positives = 120/301 (39%), Gaps = 55/301 (18%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYG-GNSATAG-----------YSQ 688 G GR GS G+ RG HG + + +G +G G G S++ G + Q Sbjct: 1701 GHGRQGSGSGQSPSRG----RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ 1756 Query: 689 FYSNGGHSGNASGGGGGGG--------GGSSGYGSYYQGDNYNSPVPPKHAGK------- 733 S GHS S G G G G +SG S + + ++ H Sbjct: 1757 HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 1816 Query: 734 ----KQPHGGQQKPSYG-----SGYQSHQGQQQSYN--QSPYSNYGPPQGKQKGYNHGQG 782 +Q G Q PS G SG+ S GQ S + S +G G+ G+ H + Sbjct: 1817 SSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES 1876 Query: 783 SYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSG-GASYNPGSHG------- 834 S S+ Y G G G +YE + SG R G +GS G+S + G HG Sbjct: 1877 SSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSR--GEQHGSSSGSSSSYGQHGSGSRQSL 1934 Query: 835 GYGG-GSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQY 893 G+G GSG G S +G + + S G SG S + SS+G Y + HS + Sbjct: 1935 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSG--SGWSSSRGPYESGSGHSSGLGH 1992 Query: 894 R 894 R Sbjct: 1993 R 1993 Score = 88.2 bits (217), Expect = 3e-17 Identities = 75/257 (29%), Positives = 109/257 (42%), Gaps = 19/257 (7%) Query: 641 GRGRGGSIRGRGRGRGFGGAN----HGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHS 696 G G S RG +G G ++ HG G+ +G G + + + +G Sbjct: 495 GSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQ 554 Query: 697 GNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQ 756 ++ G G G G SS G Y G ++S + + + Q G Q S SG+ S GQ Sbjct: 555 SSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGS-SSGHSSTHGQH 613 Query: 757 QSYN--QSPYSNYGPPQGKQKGY-NHGQGSYSYSNSYNSPGGGGG---SDYNYESKFNYS 810 S + S +G G+ + HG GS S S+ Y G G G S + S F +S Sbjct: 614 GSTSGQSSSCGQHGATSGQSSSHGQHGSGS-SQSSRYGQQGSGSGQSPSRGRHGSDFGHS 672 Query: 811 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGP 870 S G+ G GSG +S S+G +G SG S + K G S Y+ GSG ++S Sbjct: 673 SSYGQHGS---GSGWSS----SNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSG 725 Query: 871 PSSYQSSQGGYGRNADH 887 + S G R+ H Sbjct: 726 YRKHGSRSGQSSRSEQH 742 Score = 87.8 bits (216), Expect = 4e-17 Identities = 86/290 (29%), Positives = 123/290 (42%), Gaps = 39/290 (13%) Query: 635 PPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGS-YGY--GGNSATAGYSQFYS 691 P G G G S G G G ++ G + +G+ S +G G+ ++ YSQ S Sbjct: 2183 PSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS 2242 Query: 692 NGGH------SGNASGGG------GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQ-PHG 738 GH G+ SG G G SS +G + G + +S + +G Q P Sbjct: 2243 GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSR 2302 Query: 739 GQQKPSYGSGYQSHQGQQQSYN--QSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGG 796 G+ GSG+ S GQ S + S +G G+ G+ H + S S+ Y G G Sbjct: 2303 GRH--GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSG 2360 Query: 797 GGSDYNYESKFNYSG--SGGRSGGNSYGSGGASYNPGS-------HGGYGGGSGGGSS-Y 846 G +YE + SG S G G+S GS + GS HG +G GSG S Sbjct: 2361 SGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 2420 Query: 847 QGKQGGYS--QSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR 894 +G+ G S S+Y+ GSG S + SS+G Y + HS +R Sbjct: 2421 RGRHGSGSGQSSSYSPYGSG-------SGWSSSRGPYESGSGHSSGLGHR 2463 Score = 87.0 bits (214), Expect = 7e-17 Identities = 87/310 (28%), Positives = 122/310 (39%), Gaps = 37/310 (11%) Query: 611 GPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGA 670 G + + +PG G G + P G G G S G G G ++ G+ + + Sbjct: 2526 GRQGSGSGQSPGHGQRGSGSRQ-SPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 2584 Query: 671 G----YGSYGYGGNSATAGYSQFYSNGGHS------GNASGGG------GGGGGGSSGYG 714 G Y +G G+ ++GY Q S G S G++SG G G SSG+G Sbjct: 2585 GQSSSYSQHG-SGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHG 2643 Query: 715 SYYQGDNYNSPVPPKHA---GKKQPHG----GQQKPSYGSGYQSHQGQQQSYNQ----SP 763 G SP +H G HG G + S Y+S G + Q S Sbjct: 2644 RQGSGSG-QSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSG 2702 Query: 764 YSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGS 823 +S+ G G+ QG + ++ +S GS S + + GSG S + YG Sbjct: 2703 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGS-SQSSGYGR 2761 Query: 824 GGASYNPG-SHGGYGGGSGGGSSY-QGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGY 881 GA SHG +G GSG SSY Q G S Y+ GSG G Y +GG Sbjct: 2762 HGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDG----YSYCKGGS 2817 Query: 882 GRNADHSMNY 891 + S +Y Sbjct: 2818 NHDGGSSGSY 2827 Score = 86.7 bits (213), Expect = 9e-17 Identities = 87/296 (29%), Positives = 111/296 (37%), Gaps = 32/296 (10%) Query: 611 GPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSI----RGRGRGRGFGGANHGGYM 666 G +A H G G G + P RG G G S G G GR HG Sbjct: 868 GQHESASHHASGRGRHGSGSGQ-SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGS 926 Query: 667 NAGAGYGSYGYGGNSATAGYSQFYSNGGHS------GNASGGG------GGGGGGSSGYG 714 +G+G G S+ GY+Q S GHS G+ SG G G SS YG Sbjct: 927 GQSSGFGHKSSSGQSS--GYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG 984 Query: 715 SYYQGDNYNSPVPPKHAGKKQ-PHGGQQKPSYGSGYQSHQGQQQSYN--QSPYSNYGPPQ 771 + G + +G Q P + + GSG S G +S + S Y Sbjct: 985 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGS 1044 Query: 772 GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPG 831 G G H + S+ Y G G + + SG G + SG +S Sbjct: 1045 GHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS---- 1100 Query: 832 SHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG--PPSSYQSSQGGYGRNA 885 SHG +G GS S Y G+QG S SPG GQ SG SY G GR++ Sbjct: 1101 SHGQHGSGSSQSSGY-GRQGSGSG---QSPGHGQRGSGSRQSPSYGRHGSGSGRSS 1152 Score = 86.7 bits (213), Expect = 9e-17 Identities = 93/335 (27%), Positives = 133/335 (39%), Gaps = 71/335 (21%) Query: 622 GFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRG---RGFGGANHGGYMNAGAGYGS---- 674 G G G + P P RGR GS + G G G ++ G +G+G+ S Sbjct: 995 GHGQHGSGSGQSPSPS--RGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGH 1052 Query: 675 --------YGYGGNSATAGYSQFYS-NGGHSGNASGGG--GGGGGGSSGYGSYYQGDNYN 723 GYG + +++G+S + +G SG +S G G G SS +G + G + + Sbjct: 1053 RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS 1112 Query: 724 SPVPPKHAGKKQP-------HGGQQKPSYG-----SGYQSHQGQQ--------------- 756 S + +G Q G +Q PSYG SG S GQ Sbjct: 1113 SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES 1172 Query: 757 QSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGR- 815 S S YS +G G GY G + + +S G GS S + GSG R Sbjct: 1173 SSGQSSSYSQHGSGSGHSSGY----GQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 1228 Query: 816 SGGNSYGSGGASYNP------------GSHGGYGGGSGGGSS---YQGKQGGYSQSNYNS 860 S G+ G+ ++P SHG +G GSG SS Y+ + G S + Sbjct: 1229 SSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1288 Query: 861 PGSGQN--YS--GPPSSYQSSQGGYGRNADHSMNY 891 GSG + YS G S + SQG +G + S + Sbjct: 1289 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1323 Score = 86.3 bits (212), Expect = 1e-16 Identities = 88/327 (26%), Positives = 124/327 (37%), Gaps = 66/327 (20%) Query: 619 HNPGFGM---------GGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-------NH 662 H+ G+G G H + G+ GS + G GR G+ H Sbjct: 1659 HSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRH 1718 Query: 663 GGYMNAGAGYGSYGYG-GNSATAG-----------YSQFYSNGGHSGNASGGGGGGG--- 707 G + + +G +G G G S++ G + Q S GHS S G G G Sbjct: 1719 GSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFC 1778 Query: 708 -----GGSSGYGSYYQGDNYNSPVPPKHAGK-----------KQPHGGQQKPS-----YG 746 G +SG S + + ++ H +Q G Q PS G Sbjct: 1779 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 1838 Query: 747 SGYQSHQGQQQSYN--QSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYE 804 SG+ S GQ S + S +G G+ G+ H + S S+ Y G G G +YE Sbjct: 1839 SGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYE 1898 Query: 805 SKFNYSG--SGGRSGGNSYGSGGASYNPGS-------HGGYGGGSG-GGSSYQGKQGGYS 854 + SG S G G+S GS + GS HG +G GSG S +G+ G S Sbjct: 1899 QHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1958 Query: 855 --QSNYNSPGSGQNYSGPPSSYQSSQG 879 S+Y GSG +S Y+S G Sbjct: 1959 GQSSSYGPYGSGSGWSSSRGPYESGSG 1985 Score = 85.9 bits (211), Expect = 2e-16 Identities = 87/302 (28%), Positives = 120/302 (39%), Gaps = 32/302 (10%) Query: 611 GPKFAAKPHNPGFG-MGGPMHNEVPPPPNL----RGRGRGGSI----RGRGRGRGFGGAN 661 G ++ H PG G G H+E + G G G S G G+ G Sbjct: 2089 GRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 2148 Query: 662 HGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHS----------GNASGGG--GGGGGG 709 HG + + YG +G G+ ++G+ + S GHS G++S G G G G Sbjct: 2149 HGSSSGSSSRYGQHG-SGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGR 2207 Query: 710 SSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYN--QSPYSNY 767 SS G Y ++S +G Q S GSG+ QGQ S + S + Sbjct: 2208 SSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS-GSGHFCSQGQHGSTSGQSSTFDQE 2266 Query: 768 GPPQGKQKGY-NHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSG-G 825 G G+ + HG GS S S+SY G G G + + SGSG S +GSG G Sbjct: 2267 GSSTGQSSSHGQHGSGS-SQSSSYGQQGSGSGQSPSRGR--HGSGSGHSSSYGQHGSGSG 2323 Query: 826 ASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNA 885 S + G HG G S G ++ + S Y GSG +S + S G R Sbjct: 2324 WSSSSGRHGSGSGQSSGFGHHE--SSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 2381 Query: 886 DH 887 H Sbjct: 2382 RH 2383 Score = 85.5 bits (210), Expect = 2e-16 Identities = 89/296 (30%), Positives = 117/296 (39%), Gaps = 51/296 (17%) Query: 619 HNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYG 678 HN G + GRG+ GS G G+ +G HG + ++G Sbjct: 169 HNSYSGQSSSYGEQNSDSHQSSGRGQCGS--GSGQSPNYG--QHGSGSGQSSSNDTHG-S 223 Query: 679 GNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHG 738 G+ ++G+SQ S+ G S S G G G SSGYG + +S G++ Sbjct: 224 GSGQSSGFSQHKSSSGQSSGYSQHGSGSGH-SSGYGQHGSRSGQSS------RGERHRSS 276 Query: 739 GQQKPSYGSGYQSHQGQQQSY---------NQSP-YSNYGPPQGKQKGY-NHGQG-SYSY 786 SYG Q G +QS QSP + +G G + HG G SYSY Sbjct: 277 SGSSSSYG---QHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSY 333 Query: 787 SNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSG-GASYNPGSHGGYGG-----GS 840 S + G G S + SGSG SG + +GSG G S + G HG G G Sbjct: 334 SRGHYESGSGQTSGFGQHE----SGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQ 389 Query: 841 GGGSSYQGK--------------QGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 G SS Q +G +S + SPG GQ SG S S Q G G Sbjct: 390 HGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTG 445 Score = 85.1 bits (209), Expect = 3e-16 Identities = 89/295 (30%), Positives = 116/295 (39%), Gaps = 38/295 (12%) Query: 611 GPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGA 670 G ++ H+ G + GRGR GS G+ G G G+ G Sbjct: 849 GQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSG----QSP 904 Query: 671 GYGSYGYG-GNSATAGYSQFYSNGGHSGNASG-GGGGGGGGSSGYGSYYQGDNYNSPVPP 728 YG +G G G S+++G +G SG +SG G G SSGY + G Sbjct: 905 SYGRHGSGSGRSSSSG-----RHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSG------- 952 Query: 729 KHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGY-NHGQG---SY 784 H+ + HG + G +S Q S + S Y +G + G+ HG G S Sbjct: 953 -HSSSYEQHGSRS----GQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1007 Query: 785 SYSNSYNSPGGGGGSDYN-YESKFNYSGSGG---RSGGNSYGSGGASYNPGSHGGYG--G 838 S S + G G S Y Y S +S S G G+S G G G GYG G Sbjct: 1008 SPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 1067 Query: 839 GSGGGSSYQGKQG---GYSQS-NYNSPGSGQNYS-GPPSSYQSSQGGYGRNADHS 888 S G SS G+ G G S S + SGQ+ S G S S GYGR S Sbjct: 1068 SSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 1122 Score = 85.1 bits (209), Expect = 3e-16 Identities = 77/262 (29%), Positives = 104/262 (39%), Gaps = 21/262 (8%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSAT------AGYSQFYSNGG 694 G G G G+ G HG + + YG +G G ++ +G Q S G Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGR 1717 Query: 695 HS---GNASGGG--GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGY 749 H G++S G G G G SS G Y ++S +G Q S GSG+ Sbjct: 1718 HGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS-GSGH 1776 Query: 750 QSHQGQQQSYN--QSPYSNYGPPQGKQKGY-NHGQGSYSYSNSYNSPGGGGGSDYNYESK 806 QGQ S + S + G G+ + HG GS S S+SY G G G + Sbjct: 1777 FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGS-SQSSSYGQQGSGSGQSPSRGR- 1834 Query: 807 FNYSGSGGRSGGNSYGSG-GASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQ 865 + SGSG S +GSG G S + G HG G S G ++ + S Y GSG Sbjct: 1835 -HGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE--SSSWQSSGYTQHGSGS 1891 Query: 866 NYSGPPSSYQSSQGGYGRNADH 887 +S + S G R H Sbjct: 1892 GHSSSYEQHGSRSGQSSRGEQH 1913 Score = 84.0 bits (206), Expect = 6e-16 Identities = 87/286 (30%), Positives = 118/286 (41%), Gaps = 55/286 (19%) Query: 643 GRGGSIRGRGRGRG-----------FG----GANHGG-YMNAGAGYGSY-GYGGNSATAG 685 G+ GS GR RG FG G+ H Y G+G G + G + +T+G Sbjct: 1259 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 1318 Query: 686 YSQ-FYSNGGHSGNASGGG--GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQK 742 S F G +G +S G G G SSGYG + G SP +H Sbjct: 1319 QSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSG-QSPSRGRHGS---------- 1367 Query: 743 PSYGSGYQSHQGQQQSYN--QSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSD 800 GSG+ S GQ S + S +G G+ G+ H + S S+ G G G Sbjct: 1368 ---GSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHS 1424 Query: 801 YNYESKFNYSG--SGGRSGGNSYGSGGASYNPGS-------HGGYGGGSGGGSS-YQGKQ 850 +YE + SG S G G+S GS + GS HG +G GSG S +G+ Sbjct: 1425 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 1484 Query: 851 GGYS--QSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR 894 G S S+Y+ GSG S + SS+G Y + HS +R Sbjct: 1485 GSGSGQSSSYSPYGSG-------SGWSSSRGPYESGSSHSSGLGHR 1523 Score = 84.0 bits (206), Expect = 6e-16 Identities = 81/314 (25%), Positives = 122/314 (38%), Gaps = 53/314 (16%) Query: 622 GFGMGGPMHNEVPPPPNLR-GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGS------ 674 G G G + P P R G G G S G G G ++ G +G+G+ S Sbjct: 2405 GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRE 2464 Query: 675 ------YGYGGNSATAGYSQFYS-NGGHSGNASGGG--GGGGGGSSGYGSYYQGDNYNSP 725 GYG + +++G+S + +G SG +S G G G SS +G + G + +S Sbjct: 2465 SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSG 2524 Query: 726 VPPKHAGKKQP-------HGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYN 778 + +G Q G +Q PSYG + S G+ S Q +G G+ G+ Sbjct: 2525 YGRQGSGSGQSPGHGQRGSGSRQSPSYGR-HGSGSGRSSSSGQ-----HGSGLGESSGFG 2578 Query: 779 HGQGSYSYSNSYNSPGGGGGSDYNY----------------------ESKFNYSGSGGRS 816 H + S S+SY+ G G G Y S + GSG R Sbjct: 2579 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 2638 Query: 817 GGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQS 876 G S S G +G G G SS+ Q G +S G ++ G S + Sbjct: 2639 SSGHGRQGSGSGQSPSRGRHGSGLGHSSSH--GQHGSGSGRSSSRGPYESRLGHSSVFGQ 2696 Query: 877 SQGGYGRNADHSMN 890 + G G ++ +S + Sbjct: 2697 HESGSGHSSAYSQH 2710 Score = 83.6 bits (205), Expect = 8e-16 Identities = 72/260 (27%), Positives = 100/260 (38%), Gaps = 16/260 (6%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNAS 700 G+ G S G+ G + HG +GYG +G ++ G S+G S Sbjct: 226 GQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ 285 Query: 701 GGGGGG---GGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSG-YQSHQGQQ 756 G G G G G GS + H+ HG SY G Y+S GQ Sbjct: 286 HGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345 Query: 757 QSYNQ----SPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGS 812 + Q S S+ G G++ QG + ++ S G GS S + S Sbjct: 346 SGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHES 405 Query: 813 GGR-SGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPP 871 R S G S G+ +PG HG G GSG S G+ +S+ SG SG Sbjct: 406 ASRHSSGRGQHSSGSGQSPG-HGQRGSGSGQSPSSGQHGTGFGRSS----SSGPYVSG-- 458 Query: 872 SSYQSSQGGYGRNADHSMNY 891 S Y S G + +++HS Y Sbjct: 459 SGYSSGFGHHESSSEHSSGY 478 Score = 82.0 bits (201), Expect = 2e-15 Identities = 86/309 (27%), Positives = 117/309 (37%), Gaps = 60/309 (19%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHS---- 696 G G G G+ G HG + + YG +G G+ ++G+ + S GHS Sbjct: 1188 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHG-SGSRQSSGHGRQGSGSGHSPSRG 1246 Query: 697 ------GNASGGG--GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSG 748 G++S G G G G SS G Y ++S +G Q S GSG Sbjct: 1247 RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGS-GSG 1305 Query: 749 YQSHQGQQQSYN--QSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGG-------- 798 + QGQ S + S + G G+ Y H S S+ Y G G G Sbjct: 1306 HFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRH 1365 Query: 799 -SDYNYESKFNY--SGSGGRSGGNSYGSG-GASYNPGSHGG----------YGGGSGGGS 844 S + S + SGSG S +GSG G S G H +G GSG S Sbjct: 1366 GSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSS 1425 Query: 845 SYQ--GKQGGY------------SQSNYNSPGS--------GQNYSGPPSSYQSSQGGYG 882 SY+ G + G S S+Y GS GQ+ SG S S+G +G Sbjct: 1426 SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1485 Query: 883 RNADHSMNY 891 + S +Y Sbjct: 1486 SGSGQSSSY 1494 Score = 81.6 bits (200), Expect = 3e-15 Identities = 81/279 (29%), Positives = 104/279 (37%), Gaps = 37/279 (13%) Query: 619 HNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYG 678 H G G G H + +GR GS G+ G H + YG + Sbjct: 820 HESGSGQGYSQHGSASG--HFSSQGRHGSTSGQSSSSG----QHDSSSGQSSSYGQH--- 870 Query: 679 GNSATAGYSQFYSNGGHSGNASGGG--GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQP 736 SA+ S +G SG + G G G G G S YG + G +S +G+ Sbjct: 871 -ESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSS-----SSGR--- 921 Query: 737 HGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGY-NHGQGSYSYSNSYNSPGG 795 HG S G G++S GQ Y Q +G G Y HG S S S Sbjct: 922 HGSGSGQSSGFGHKSSSGQSSGYTQ-----HGSGSGHSSSYEQHGSRSGQSSRSEQHGSS 976 Query: 796 GGGSDYNYESKFNYSGSGGRS--GGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGY 853 G S S + GSG R G +GSG S G +G GSG SSY + G Sbjct: 977 SGSS-----SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGS 1031 Query: 854 SQSNYNSP---GSGQNYS-GPPSSYQSSQGGYGRNADHS 888 S+ P GSG + G S GYG++ S Sbjct: 1032 GWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS 1070 Score = 80.5 bits (197), Expect = 6e-15 Identities = 76/321 (23%), Positives = 119/321 (37%), Gaps = 41/321 (12%) Query: 603 RAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANH 662 ++P R G F G G + P ++ G+ G + G G+ G + H Sbjct: 658 QSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKS-GSGQSSGYSQH 716 Query: 663 GGYMNAGAGYGSYG-----------YGGNSA-TAGYSQF----YSNGGHSGNASGGG--- 703 G + +GY +G +G +S ++ Y Q + + GH SG G Sbjct: 717 GSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSP 776 Query: 704 -----GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHG-GQQKPSYGSGYQSH----- 752 G G SS +G + G + +S +G Q G GQ + G GY H Sbjct: 777 SRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASG 836 Query: 753 ----QGQQQSYN--QSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESK 806 QG+ S + S + G+ Y + + +++ G G G + + Sbjct: 837 HFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQR 896 Query: 807 FNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQN 866 + SG G + GSG +S S G +G GSG S + K S Y GSG Sbjct: 897 GSGSGQSPSYGRHGSGSGRSS----SSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSG 952 Query: 867 YSGPPSSYQSSQGGYGRNADH 887 +S + S G R+ H Sbjct: 953 HSSSYEQHGSRSGQSSRSEQH 973 Score = 77.4 bits (189), Expect = 5e-14 Identities = 86/318 (27%), Positives = 114/318 (35%), Gaps = 60/318 (18%) Query: 609 RGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNA 668 R G ++ H G+ G GR GS G G HG Sbjct: 732 RSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGS----GSGHSPSRVRHGSSSGH 787 Query: 669 GAGYGSYGYGGN-SATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVP 727 + +G +G G + S++ G+ Y +G SG ASG G G GY + Sbjct: 788 SSSHGQHGSGTSCSSSCGH---YESG--SGQASGFGQHESGSGQGYSQHGSASG------ 836 Query: 728 PKHAGKKQPHGGQQKPSYGSG-YQSHQGQQQSYNQ--------SPYSNYGPPQGKQKGYN 778 H + HG S SG + S GQ SY Q S +G G+ G+ Sbjct: 837 --HFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHG 894 Query: 779 HGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGY-- 836 S SY G G G + + SG G G S G G S + G GY Sbjct: 895 QRGSGSGQSPSYGRHGSGSG-------RSSSSGRHGSGSGQSSGFGHKS-SSGQSSGYTQ 946 Query: 837 -GGGSGGGSSYQ--GKQGGY------------SQSNYNSPGS--------GQNYSGPPSS 873 G GSG SSY+ G + G S S+Y GS GQ+ SG S Sbjct: 947 HGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQS 1006 Query: 874 YQSSQGGYGRNADHSMNY 891 S+G +G + S +Y Sbjct: 1007 PSPSRGRHGSGSGQSSSY 1024 Score = 75.5 bits (184), Expect = 2e-13 Identities = 98/349 (28%), Positives = 131/349 (37%), Gaps = 64/349 (18%) Query: 603 RAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRG-------- 654 R P R G H G G + +G+ GS G+ Sbjct: 1271 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1330 Query: 655 --------RGFGGANHGGYMNAGAGYG-SYGYGGNSATAGYSQFYS-NGGHSG--NASGG 702 RG G + GY GAG G S G + + +G+S Y +G SG ++SG Sbjct: 1331 GQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR 1390 Query: 703 GGGGGGGSSGYGSYYQGDNYNSPVPPK-----HAGKKQPHGGQQ-KPSYGSGYQSHQGQQ 756 G G G SSG+G + +S H+ + HG + + S G + S G Sbjct: 1391 HGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 1450 Query: 757 QSYNQSP--------YSNYGPPQGKQKGYN---HGQGSYSYSNSYNSPGGGGG---SDYN 802 SY Q + +G G+ + HG GS S+SY+ G G G S Sbjct: 1451 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS-GQSSSYSPYGSGSGWSSSRGP 1509 Query: 803 YESKFNYSGSGG----RSGGNS-YG----SGGASYNPGSHGG----------YGGGSGGG 843 YES ++S G RSG +S YG S G S G HG +G SG Sbjct: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQS 1569 Query: 844 SSYQGKQGGYSQSN-YNSPGSGQNYS---GPPSSYQSSQGGYGRNADHS 888 SS+ G SQS+ Y GSG S G S YGR+ S Sbjct: 1570 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1618 Score = 75.5 bits (184), Expect = 2e-13 Identities = 76/270 (28%), Positives = 99/270 (36%), Gaps = 27/270 (10%) Query: 635 PPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATA----GYSQFY 690 P G G G S G G G ++ G +G+G S G+G + +++ GY+Q Sbjct: 1830 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQHG 1888 Query: 691 SNGGHSGNASGGGGGGG--------GGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQK 742 S GHS + G G G SSG S Y S H G Sbjct: 1889 SGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1948 Query: 743 PSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYN 802 PS G + S GQ SY P G G++ +G Y + ++S G S Sbjct: 1949 PSRGR-HGSGSGQSSSYG---------PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSG 1998 Query: 803 YESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSN-YNSP 861 S + GS G AS S G +G SG SS+ G SQS+ Y Sbjct: 1999 QSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2058 Query: 862 GSGQNYS---GPPSSYQSSQGGYGRNADHS 888 GSG S G S YGR+ S Sbjct: 2059 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 2088 Score = 75.1 bits (183), Expect = 3e-13 Identities = 76/247 (30%), Positives = 99/247 (40%), Gaps = 33/247 (13%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGA----GYGSYGYG-GNSATAGYSQFYSNGGH 695 G G S RG G G ++H G +G+ G+G G G G S + G + S GH Sbjct: 2607 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRG--RHGSGLGH 2664 Query: 696 SGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQ 755 S ++ G G G G SS G Y ++S +G Q S GSG+ QGQ Sbjct: 2665 S-SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGS-GSGHFCSQGQ 2722 Query: 756 QQSYN--QSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSG 813 S + S + G G+ Y H S S+ Y G G G ++ Sbjct: 2723 HGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSH---------- 2772 Query: 814 GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGK---QGGYSQ----SNYNSPGSGQN 866 GR G S G S + G HG G G G S G Q GYS SN++ SG Sbjct: 2773 GRHGSGS----GQSSSYGQHGS-GSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSY 2827 Query: 867 YSGPPSS 873 + PSS Sbjct: 2828 FLSFPSS 2834 Score = 74.7 bits (182), Expect = 4e-13 Identities = 79/276 (28%), Positives = 108/276 (39%), Gaps = 39/276 (14%) Query: 635 PPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATA----GYSQFY 690 P G G G S G G G ++ G +G+G S G+G + +++ GY+Q Sbjct: 2300 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQHG 2358 Query: 691 SNGGHSGNASGGGGGGG--------GGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQK 742 S GHS + G G G SSG S Y S H G Sbjct: 2359 SGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 2418 Query: 743 PSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYN 802 PS G + S GQ SY+ P G G++ +G Y + ++S G + Sbjct: 2419 PSRGR-HGSGSGQSSSYS---------PYGSGSGWSSSRGPYESGSGHSSGLG------H 2462 Query: 803 YESKFNYSGSGGRSGGNS-----YGSGGASYNPGSHGGYGGGSGGGSSYQGKQG-GYSQS 856 ES+ S G+ G +S +G G++ S G G S G SS G+ G G SQS Sbjct: 2463 RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS 2522 Query: 857 N-YNSPGSGQNYS---GPPSSYQSSQGGYGRNADHS 888 + Y GSG S G S YGR+ S Sbjct: 2523 SGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 2558 Score = 72.4 bits (176), Expect = 2e-12 Identities = 83/293 (28%), Positives = 113/293 (38%), Gaps = 39/293 (13%) Query: 619 HNPGFGMGGPM---------HNEVPPPPNLRGRGRGGSIRGRGRGR-GFGGANHGGYMNA 668 H+ G+G G H + G+ GS + G GR G G ++ Sbjct: 253 HSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRH 312 Query: 669 GAGYG---SYGYGGNSATAGYSQFYSNGGHSGNASGGGG--GGGGGSSGYGSYYQGDNYN 723 G+G G S+G G+ ++ YS+ + G SG SG G G G SSGY + G ++ Sbjct: 313 GSGSGHSSSHGQHGSGSSYSYSRGHYESG-SGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371 Query: 724 SPVPPKHAGKKQPHGGQQKPSYGSGYQSHQ----GQQQSYNQSPYSNYGPPQGKQKGYNH 779 S G+ GQ S G S Q GQ +S ++ G + H Sbjct: 372 SS-----QGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGH 426 Query: 780 GQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSG------GNSYGSGGASYNPGS- 832 GQ S +S G G + S SGSG SG + + SG + GS Sbjct: 427 GQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSG 486 Query: 833 ----HGGYGGGSGGGS--SYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQG 879 HG +G SG S QG G S S+Y GSG S S + S G Sbjct: 487 HSSGHGQHGSRSGQSSRGERQGSSAG-SSSSYGQHGSGSRQSLGHSRHGSGSG 538 Score = 59.7 bits (143), Expect = 1e-08 Identities = 56/205 (27%), Positives = 80/205 (39%), Gaps = 31/205 (15%) Query: 700 SGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSY 759 SG G SS YG + +S G+ + GSG + GQ S Sbjct: 166 SGQHNSYSGQSSSYGEQNSDSHQSS--------------GRGQCGSGSGQSPNYGQHGSG 211 Query: 760 NQSPYSN--YGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGR-- 815 + SN +G G+ G++ + S S+ Y+ G G G Y + SG R Sbjct: 212 SGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGE 271 Query: 816 ------SGGNSYGS-GGASYNPGSHGGYGGGSGGGSSY--QGKQGGYSQSNYNSPGSGQN 866 +SYG G S HG G GS S+ G G+S S++ GSG + Sbjct: 272 RHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHS-SSHGQHGSGSS 330 Query: 867 YSGPPSSYQSSQG---GYGRNADHS 888 YS Y+S G G+G++ S Sbjct: 331 YSYSRGHYESGSGQTSGFGQHESGS 355 Score = 46.6 bits (109), Expect = 1e-04 Identities = 47/167 (28%), Positives = 66/167 (39%), Gaps = 29/167 (17%) Query: 745 YGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYE 804 + + S+ GQ SY + ++ Q G GQ S +Y G G G + + Sbjct: 165 FSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQ-----SPNYGQHGSGSGQSSSND 219 Query: 805 SKFNYSGSGGRSG--------GNS-----YGSG-GASYNPGSHGGYGGGSGGGSSYQGKQ 850 + + SGSG SG G S +GSG G S G HG G S G ++ Sbjct: 220 T--HGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSS 277 Query: 851 GGYSQSNYNSPGSGQNYS------GPPSSYQSSQGGYGRNADHSMNY 891 G S S+Y GSG S G S S +G + HS ++ Sbjct: 278 G--SSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSH 322 Score = 32.0 bits (71), Expect = 2.6 Identities = 36/145 (24%), Positives = 53/145 (36%), Gaps = 22/145 (15%) Query: 754 GQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSG 813 G+ SY+++ + P G + +S +NS G S S + S Sbjct: 135 GENDSYSRNVRGSLKP--GTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGR 192 Query: 814 GRSGGNSYGSGGASYNPGSHGGYGGGSGGG---------SSYQGKQGGYSQSNYNS-PGS 863 G+ G S G S N G HG G S G+ G+SQ +S S Sbjct: 193 GQCGSGS----GQSPNYGQHG------SGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSS 242 Query: 864 GQNYSGPPSSYQSSQGGYGRNADHS 888 G + G S + S G +G + S Sbjct: 243 GYSQHGSGSGHSSGYGQHGSRSGQS 267 >gi|62122917 filaggrin family member 2 [Homo sapiens] Length = 2391 Score = 91.7 bits (226), Expect = 3e-18 Identities = 80/257 (31%), Positives = 111/257 (43%), Gaps = 20/257 (7%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNAS 700 G G+ GS G + GFG +G AG+G +G G+ ++G+ Q S S + Sbjct: 793 GFGQHGS--GSSQSTGFG--QYGSGSGQSAGFGQHG-SGSGQSSGFGQHESRSHQS--SY 845 Query: 701 GGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYN 760 G G G SSGYG + S +H + G + GSG S GQ + Sbjct: 846 GQHGSGSSQSSGYGQHGSSSGQTSGF-GQHRSSSGQYSGFGQHGSGSGQSSGFGQHGT-G 903 Query: 761 QSPYSNYGPPQGK--QKGY-NHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSG 817 YS +G + + Q Y HG GS S S+ Y G G + + + SGSG SG Sbjct: 904 SGQYSGFGQHESRSHQSSYGQHGSGS-SQSSGYGQHGSSSGQTFGFGQ--HRSGSGQSSG 960 Query: 818 GNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSS 877 +GSG S G + GSG S + + SQSNY GSG + S + SS Sbjct: 961 FGQHGSG--SGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSS 1018 Query: 878 QG---GYGRNADHSMNY 891 G G+G++ S Y Sbjct: 1019 SGQTTGFGQHRSSSGQY 1035 Score = 91.3 bits (225), Expect = 4e-18 Identities = 90/290 (31%), Positives = 120/290 (41%), Gaps = 49/290 (16%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAG-------AGYGSYGY--GGNSATAGYSQFYS 691 G G+ GS G G+ GFG G ++G +G SYG G+S ++GY Q Sbjct: 579 GFGQYGS--GSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQ--- 633 Query: 692 NGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQS 751 +G + G G G S+G+G Y G +S +G Q G Q S SG+ S Sbjct: 634 HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHES-RSGHSS 692 Query: 752 HQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSG 811 + Q + S S YG G G G G + S+ +S G GS S F G Sbjct: 693 Y--GQHGFGSSQSSGYG-QHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHG 749 Query: 812 SG-----------GRSGGNSYG--SGGASYNPGSHGGYG-------GGSGGGSSYQGKQG 851 SG RSG +SYG S G+S + G +G +G G G GSS G Sbjct: 750 SGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSG-YGQHGSRQTSGFGQHGSGSSQSTGFG 808 Query: 852 GYSQSNYNSPGSGQNYSG----------PPSSYQSSQGGYGRNADHSMNY 891 Y + S G GQ+ SG S+QSS G +G + S Y Sbjct: 809 QYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGY 858 Score = 86.3 bits (212), Expect = 1e-16 Identities = 76/286 (26%), Positives = 110/286 (38%), Gaps = 35/286 (12%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYG--------YGGNSATAGYSQFYSN 692 G+ G G G G+ G HG +G+G +G +G + + + S + + Sbjct: 487 GQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQH 546 Query: 693 GGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSH 752 G S +SG G G +SG+G + G ++ +G Q G Q S GSG S Sbjct: 547 GSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGS-GSGQSSG 605 Query: 753 QGQQQSYN-QSPYSNYGPPQGKQKGY------------NHGQGSYSYSNSYNSPGGGGGS 799 GQ +S + QS Y + + GY HG GS S S + G G G Sbjct: 606 FGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGS-SQSTGFGQYGSGSGQ 664 Query: 800 DYNYESKFNYSGSG-------GRSGGNSYGSGG----ASYNPGSHGGYGGGSGGGSSYQG 848 + + SG RSG +SYG G S G HG G + G ++ Sbjct: 665 SSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHEL 724 Query: 849 KQGGYSQSNYNSPGSGQNYS-GPPSSYQSSQGGYGRNADHSMNYQY 893 G S + GSGQ+ G S G+G++ S Y Sbjct: 725 SSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770 Score = 83.6 bits (205), Expect = 8e-16 Identities = 79/274 (28%), Positives = 111/274 (40%), Gaps = 51/274 (18%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAG----------YGSYGYGGNSATAGYSQFY 690 G G+ GS G G+ GFG G ++G G YG +G G+S ++GY Q Sbjct: 806 GFGQYGS--GSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHG-SGSSQSSGYGQHG 862 Query: 691 SNGGH----------SGNASGGG--GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHG 738 S+ G SG SG G G G G SSG+G + G +G+ G Sbjct: 863 SSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTG-----------SGQYSGFG 911 Query: 739 GQQKPSYGSGYQSH-QGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGG 797 + S+ S Y H G QS S Y +G G+ G+ + S+ + G G Sbjct: 912 QHESRSHQSSYGQHGSGSSQS---SGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGS 968 Query: 798 GSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSN 857 G + + SGSG SG + S + N G HG GSS G + S+ Sbjct: 969 GQSSGFGQ--HESGSGKSSGFGQHESRSSQSNYGQHGS-------GSSQSSGYGQHGSSS 1019 Query: 858 YNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNY 891 + G GQ+ S S S G +G +D S + Sbjct: 1020 GQTTGFGQHRSS--SGQYSGFGQHGSGSDQSSGF 1051 Score = 77.0 bits (188), Expect = 7e-14 Identities = 82/276 (29%), Positives = 112/276 (40%), Gaps = 37/276 (13%) Query: 643 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSY--------GYGGNSATAGYSQFYSNGG 694 G G G G+ GFG HG +G+G + G+G + + + S + +G Sbjct: 947 GFGQHRSGSGQSSGFG--QHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGS 1004 Query: 695 HSGNASGGG--GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSH 752 S +SG G G G ++G+G + S +G Q G Q + GSG S Sbjct: 1005 GSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGT-GSGQSSG 1063 Query: 753 QGQQQSYN-QSPYSNYGPPQGKQKGYN-HGQGSYSYSN-SYNSPGGGG-------GSDYN 802 GQ +S + QS Y +G + GY HG S S + PG G GS Sbjct: 1064 FGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSG 1123 Query: 803 YESKFNYSGSG-GRSGG---NSYGSGGASYNPGSHG-GYGGGSGGGSSYQGKQ-----GG 852 S F GSG G+S G + Y SG +SY G HG G SG G G G Sbjct: 1124 QSSGFGQHGSGTGKSSGFAQHEYRSGQSSY--GQHGTGSSQSSGCGQHESGSGPTTSFGQ 1181 Query: 853 YSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHS 888 + + N SGQ+ S S + G YG + S Sbjct: 1182 HVSGSDNFSSSGQHIS--DSGQSTGFGQYGSGSGQS 1215 Score = 76.3 bits (186), Expect = 1e-13 Identities = 81/284 (28%), Positives = 111/284 (39%), Gaps = 50/284 (17%) Query: 650 GRGRGRGFGGANHGGYMNAGAGYGSYGYGG----------NSATAGYSQFYSNGGHSGNA 699 G G + HG ++ +G+ + G +S + GY Q +G SG Sbjct: 420 GSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQ---HGSSSGKT 476 Query: 700 SGGG--GGGGGGSSGYGSYYQGDNYNS------PVPPKHAGKKQPHGGQQKPSYGSGYQS 751 SG G G G G SSG+G G +S V + +G Q HG S G G Sbjct: 477 SGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQ-HGSVSGQSSGFGQHE 535 Query: 752 HQGQQQSYNQ--------SPYSNYGPPQ-------GKQKGYNHGQGSY----SYSNSYNS 792 + +Q SY Q S Y YG + G G + G G Y S+ + Sbjct: 536 SRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQ 595 Query: 793 PGGGGGSDYNY---ESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGK 849 G G G + ES+ S G S G+S SG + G+ G G GSS Sbjct: 596 HGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF-GQHGSGSSQSTG 654 Query: 850 QGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQY 893 G Y + S G GQ+ SG S QSS G+G++ S + Y Sbjct: 655 FGQYGSGSGQSSGFGQHVSG---SGQSS--GFGQHESRSGHSSY 693 Score = 70.1 bits (170), Expect = 9e-12 Identities = 88/321 (27%), Positives = 127/321 (39%), Gaps = 53/321 (16%) Query: 611 GPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGG----------A 660 G F H G G G G+ S G G+ GFG Sbjct: 943 GQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHES--GSGKSSGFGQHESRSSQSNYG 1000 Query: 661 NHGGYMNAGAGYGSYG--------YGGNSATAG-YSQFYSNGGHSGNASGGG--GGGGGG 709 HG + +GYG +G +G + +++G YS F +G S +SG G G G G Sbjct: 1001 QHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQ 1060 Query: 710 SSGYGSYYQGDNYNSPVPPKHAGKKQPHG-GQQKPSYG--SGYQSHQ---GQQQSYNQ-- 761 SSG+G Y + + S +G Q G GQ + G SG+ H+ GQ + Q Sbjct: 1061 SSGFGQY-ESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYG 1119 Query: 762 ------SPYSNYGPPQGKQKG-----YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYS 810 S + +G GK G Y GQ SY + +S G G +ES + Sbjct: 1120 SGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCG---QHESGSGPT 1176 Query: 811 GSGGR--SGGNSYGSGGASY-NPGSHGGYGG-GSGGGSSYQGKQGGYSQSNYNSPGSGQ- 865 S G+ SG +++ S G + G G+G GSG G S QG Q S G+ Sbjct: 1177 TSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQ 1236 Query: 866 --NYSGPPSSYQSSQGGYGRN 884 + ++ + SQ G G++ Sbjct: 1237 ETTHGQTINTTRHSQSGQGQS 1257 Score = 53.5 bits (127), Expect = 8e-07 Identities = 84/314 (26%), Positives = 109/314 (34%), Gaps = 58/314 (18%) Query: 630 HNEVPPPPNLRGRGRGGSIRGRG----RGRGFGGANHGGY---MNAGAGYGSYGYGGNSA 682 H +R + G S G G R G +N G NA + S+ +GG Sbjct: 249 HESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGN 308 Query: 683 TAGYSQFYSNGGHSGNASGGGGG--GGGGSSGYG---------SYYQ-GDNYNSPVPPKH 730 Y Q +G SG G G G GG SG G SY Q G P++ Sbjct: 309 QFSYIQ---SGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQN 365 Query: 731 AGKKQPHGGQQKP---SYGSG--YQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYS 785 G + G Q YGSG GQ + + +SN K +G GS S Sbjct: 366 CGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGS-S 424 Query: 786 YSNSYNSPGGGGGSDYNYESKFNYSGSGGRSG---------------GNSYGSGGASYNP 830 S S+ G G +E + GSG G G+S G Sbjct: 425 QSTSFEQHGTGLSQSSGFEQ--HVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQH 482 Query: 831 GSHGGYGGGSGGGSSYQGKQGGYSQS---NYNSPGSGQ--NYSGPPSSY--------QSS 877 GS G G G S G+ G+ Q + S G GQ + SG S + QSS Sbjct: 483 GSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSS 542 Query: 878 QGGYGRNADHSMNY 891 G +G + S Y Sbjct: 543 YGQHGSGSSQSSGY 556 Score = 48.5 bits (114), Expect = 3e-05 Identities = 71/271 (26%), Positives = 106/271 (39%), Gaps = 32/271 (11%) Query: 642 RGRGGSIRGRGRGRGFGGANHGGYMNAGAGY-----GSYGYGGNSATAGYSQFYSNGGHS 696 RG G S G H G+ + AG GS + + T G + + GHS Sbjct: 1951 RGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHS 2010 Query: 697 GNASGGGGGG---GGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQ 753 G+ G G +SG+ Y + + S V H+G G Q GS Sbjct: 2011 GHGQSTQRGSRTTGRRASGHSEYSDSEGH-SGVSHTHSGHAHGQAGSQHGESGSSVHERH 2069 Query: 754 G--QQQSYNQSPYSNYGPPQGKQ--------KGYNHGQGSYSYSNSYNSPGGGGGSDYNY 803 G Q+ + + +++ G Q Q +G H + S S +S S G + Sbjct: 2070 GTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQA 2129 Query: 804 ESKFNYSGSG--GRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQ-GGYSQSNYN- 859 S+ SGS GR G +G G + G G+G + GS G+Q +S+S+ + Sbjct: 2130 RSQHGESGSAIHGRQ-GTIHGQTGDTTRHG-QSGHGQSTQTGSRTTGRQRSSHSESSDSE 2187 Query: 860 -----SP-GSGQNYSGPPSSY-QSSQGGYGR 883 SP SG +S S + QS G+GR Sbjct: 2188 VHSEASPTHSGHTHSQAGSRHGQSGSSGHGR 2218 Score = 48.5 bits (114), Expect = 3e-05 Identities = 58/266 (21%), Positives = 92/266 (34%), Gaps = 46/266 (17%) Query: 649 RGRGRGRGFGGANHGGYMNAGAGYGSYGYG----GNSATAGYSQFYSNGGHSGNASGGGG 704 RG G H G + +G+ +YG G S +A + + + G +G+ + G Sbjct: 2101 RGSGHSESSDSEVHSGVSHTHSGH-TYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQ 2159 Query: 705 GGGGGSSGYGSYYQG-----------DNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQ 753 G G S+ GS G +S P H+G G + GS Q Sbjct: 2160 SGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQ 2219 Query: 754 GQQ--QSYNQSPYSNYGPPQGKQKGYN-----------------HGQGSYSYSNSYNSPG 794 G Q+ + + +++YG Q Q+G H GS+++S Sbjct: 2220 GTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQA 2279 Query: 795 G------GGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGG-----G 843 G G E+ +G R G + YG + + S + G Sbjct: 2280 GSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSSERQRHG 2339 Query: 844 SSYQGKQGGYSQSNYNSPGSGQNYSG 869 SS K G Y + Y+ +G SG Sbjct: 2340 SSQVWKHGSYGPAEYDYGHTGYGPSG 2365 Score = 47.0 bits (110), Expect = 8e-05 Identities = 72/298 (24%), Positives = 106/298 (35%), Gaps = 47/298 (15%) Query: 627 GPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYG-SYGYGGNSATAG 685 G H + G G S + R G G+ H ++ G S+ + G++ Sbjct: 2070 GTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHT---- 2125 Query: 686 YSQFYSNGGHSGNASGG---------------GGGGGGGSSGYGSYYQG----------- 719 Y Q S G SG+A G G G G S+ GS G Sbjct: 2126 YGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSD 2185 Query: 720 DNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQG--QQQSYNQSPYSNYGPPQGKQKG- 776 +S P H+G G + GS QG Q+ + + +++YG Q Q+G Sbjct: 2186 SEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGS 2245 Query: 777 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN--------SYGSGGASY 828 G+ +S S +S GS + +GS R G+ ++G G + Sbjct: 2246 RTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTT 2305 Query: 829 NPGSHGGYGGGSGGGS-SYQGKQGGYSQSNYNSPGSGQNY---SGPPSSYQSSQGGYG 882 G H GYG + GS S + S GS Q + S P+ Y GYG Sbjct: 2306 RHG-HSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYG 2362 Score = 45.8 bits (107), Expect = 2e-04 Identities = 64/255 (25%), Positives = 99/255 (38%), Gaps = 46/255 (18%) Query: 651 RGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGS 710 RG G G+ HG + +G T+G+SQ GH + G G Sbjct: 1822 RGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQ----SGHGQSTQSGSSTTGRRR 1877 Query: 711 SGYGSYYQGDNYNSPVPPKHAGKKQPHGG----QQKPSYGSGYQS-HQGQQQSYNQS-PY 764 SG+ ++ +S V H+G H G Q + +G + H+ Q ++ Q+ Sbjct: 1878 SGHS-----ESSDSEV---HSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDT 1929 Query: 765 SNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSG------G 818 + +G P +HGQ + S + G G YS S G SG G Sbjct: 1930 TEHGHP-------SHGQTIQTGSRTTGRRGSGHSE---------YSDSEGPSGVSHTHSG 1973 Query: 819 NSYGSGGASY-NPGS--HGGYG--GGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSS 873 +++G G+ Y GS H +G G ++ G G + S +G+ SG S Sbjct: 1974 HTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASG-HSE 2032 Query: 874 YQSSQGGYGRNADHS 888 Y S+G G + HS Sbjct: 2033 YSDSEGHSGVSHTHS 2047 Score = 41.2 bits (95), Expect = 0.004 Identities = 39/155 (25%), Positives = 61/155 (39%), Gaps = 25/155 (16%) Query: 642 RGRGGSIRGRGRGRGFGGANHGGYMNAGAGY-----GSYGYGGNSATAGYSQFYSNGGHS 696 RG G S +G H G++ AG GS +G T G + + GHS Sbjct: 2251 RGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHS 2310 Query: 697 GNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQ 756 G G G S S++Q H+ ++Q HG Q +GS + + Sbjct: 2311 GY---GQSTQTGSRSSRASHFQS----------HSSERQRHGSSQVWKHGS----YGPAE 2353 Query: 757 QSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYN 791 Y ++ YGP G +K ++ S+S ++ N Sbjct: 2354 YDYG---HTGYGPSGGSRKSISNSHLSWSTDSTAN 2385 Score = 38.5 bits (88), Expect = 0.028 Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 31/215 (14%) Query: 679 GNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPH- 737 G S + + + + G +G A+G G G G S+ GS G + + + H Sbjct: 1378 GESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGH---SESSDSEVHS 1434 Query: 738 GGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGG 797 GG +P Q Q+Q++ Q+ G G+ HG+ + ++ G Sbjct: 1435 GGSHRP---------QSQEQTHGQA-----GSQHGESGSTVHGR----HGTTHGQTGDTT 1476 Query: 798 GSDYNYESKFNYSGS---GGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS 854 + + K GS G R G+S S ++ GSH G G S G+ Sbjct: 1477 RHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESII 1536 Query: 855 QSNY------NSPGSGQNYSGPPSSYQSSQGGYGR 883 + + +YSG + Q+ GR Sbjct: 1537 HDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGR 1571 Score = 38.1 bits (87), Expect = 0.037 Identities = 69/235 (29%), Positives = 83/235 (35%), Gaps = 56/235 (23%) Query: 685 GYSQFYSNGG----HSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQ 740 GYS +S G H N+ G G SSG Q + S +G K HG Sbjct: 141 GYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGS- 199 Query: 741 QKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGG--- 797 S ++ N+S S P + + Y G G SNS+ G GG Sbjct: 200 ----------SSVELRERINKSHIS---PSRESGEEYESGSG----SNSWERKGHGGLSC 242 Query: 798 -----GSDYN------YESKFNYSGSG-GRSGGNSYGSG-----------GASYNPGSH- 833 G + N E K S SG G SG S+ G AS + SH Sbjct: 243 GLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQSHR 302 Query: 834 -GGYGG-----GSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 GG G SG S +G QG S G GQ S P S SQ GYG Sbjct: 303 FGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESN-PCSQSYSQRGYG 356 Score = 38.1 bits (87), Expect = 0.037 Identities = 52/228 (22%), Positives = 74/228 (32%), Gaps = 38/228 (16%) Query: 629 MHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQ 688 +H+E P + + GS G+ G + HG G +G G A GY Q Sbjct: 2188 VHSEASPTHSGHTHSQAGSRHGQS-----GSSGHG---RQGTTHGQTGDTTRHAHYGYGQ 2239 Query: 689 FYSNGGHSGNASGGGGGGGGGSS--GYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYG 746 G + G G S +GS+ H+G Q G Q+ G Sbjct: 2240 STQRGSRTTGRRGSGHSESSDSEVHSWGSH------------THSGHIQGQAGSQQRQPG 2287 Query: 747 SGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESK 806 S H + ++ Q+ + HG Y S S ++ S+ Sbjct: 2288 STV--HGRLETTHGQTGDTT-----------RHGHSGYGQSTQTGSRSSRASHFQSHSSE 2334 Query: 807 FNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS 854 GS SYG A Y+ G H GYG G S +S Sbjct: 2335 RQRHGSSQVWKHGSYGP--AEYDYG-HTGYGPSGGSRKSISNSHLSWS 2379 Score = 34.7 bits (78), Expect = 0.41 Identities = 42/225 (18%), Positives = 80/225 (35%), Gaps = 21/225 (9%) Query: 674 SYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGK 733 +YG G + G+S + G+ + G G G S + G ++ + + Sbjct: 1391 TYGQTGEATGHGHSG-HGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSH------RPQSQ 1443 Query: 734 KQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSP 793 +Q HG SG H ++ Q+ + + Y+HG+ + S++ Sbjct: 1444 EQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTT------RHAHYHHGKSTQRGSSTTGRR 1497 Query: 794 GGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGS---HGGY--GGGSGGGSSYQG 848 G G + E +SG G+++G G+ + H + G G ++ Sbjct: 1498 GSGHSESSDSEV---HSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHS 1554 Query: 849 KQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQY 893 G + S +G+ + S S G + HS + Y Sbjct: 1555 YSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTY 1599 Score = 33.5 bits (75), Expect = 0.91 Identities = 56/246 (22%), Positives = 84/246 (34%), Gaps = 38/246 (15%) Query: 653 RGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSG 712 R G G+ H Y + S GY G S T HSG+ G G S Sbjct: 1719 RTTGRRGSGHSEYSD------SEGYSGVSHT-----------HSGHTHGQARSQHGESES 1761 Query: 713 YGSYYQGDNYNSPVPP-KHA----GKKQPHGGQQKPSYGSGYQSHQGQQ--QSYNQSPYS 765 G + +HA G+ G + SG+ + + ++Q P+S Sbjct: 1762 IVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHS 1821 Query: 766 NYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGG-------SDYNYESKFNYSGSGGRSGG 818 G G Q G HG+ + + G G S + ++ S +G R G Sbjct: 1822 R-GHTHG-QAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSG 1879 Query: 819 NSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGG----YSQSNYNSPGSGQNYSGPPSSY 874 +S S ++ GSH G S G+ Q+ + G + G PS Sbjct: 1880 HSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEH-GHPSHG 1938 Query: 875 QSSQGG 880 Q+ Q G Sbjct: 1939 QTIQTG 1944 Score = 30.4 bits (67), Expect = 7.7 Identities = 34/148 (22%), Positives = 53/148 (35%), Gaps = 11/148 (7%) Query: 739 GQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGG 798 G +K G +Q + + + + G + GY H S + Y+S G Sbjct: 98 GSKKHRRGHRHQEEESETEEDEEDT-------PGHKSGYRHSSWSEGEEHGYSSGHSRGT 150 Query: 799 SDYNYESKFNYSGSGGR--SGGNSYGSGGASYNPG-SHGGYGGGSGGGSSYQGKQGGYSQ 855 + S G G S GN GS + H GG GSS + ++ Sbjct: 151 VKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINK 210 Query: 856 SNYN-SPGSGQNYSGPPSSYQSSQGGYG 882 S+ + S SG+ Y S + G+G Sbjct: 211 SHISPSRESGEEYESGSGSNSWERKGHG 238 >gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b [Homo sapiens] Length = 372 Score = 90.1 bits (222), Expect = 8e-18 Identities = 74/214 (34%), Positives = 90/214 (42%), Gaps = 41/214 (19%) Query: 642 RGRGGSIR-GRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYS---QFYSNGGHSG 697 RGR GS G GRG GFGG ++ G +G G G+GG+ GY Y+ G+ G Sbjct: 194 RGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRG--GFGGSRGGGGYGGSGDGYNGFGNDG 251 Query: 698 NASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQ 757 GGG G GGS GYGS GGQ + GSGY G Sbjct: 252 GYGGGGPGYSGGSRGYGS----------------------GGQGYGNQGSGY-GGSGSYD 288 Query: 758 SYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSG 817 SYN +G G G G GSY+ +YN+ G GGRS Sbjct: 289 SYNNGGGGGFGGGSGSNFG---GGGSYNDFGNYNNQSSNFG-------PMKGGNFGGRSS 338 Query: 818 GNSYGSGGASY-NPGSHGGYGGGSGGGSSYQGKQ 850 G YG GG + P + GGYGG S S G++ Sbjct: 339 G-PYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRR 371 Score = 75.1 bits (183), Expect = 3e-13 Identities = 80/230 (34%), Positives = 87/230 (37%), Gaps = 78/230 (33%) Query: 610 GGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRG----RGRGFGG-ANHGG 664 GG + N FG GG N GRG G RG G G G+ G N GG Sbjct: 203 GGGRGGGFGGNDNFGRGG----------NFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGG 252 Query: 665 YMNAGAGY--GSYGYGGNSATAGYSQFYSNGGHSG------NASGGGGGGGGGSS--GYG 714 Y G GY GS GYG S GY S G SG N GGG GGG GS+ G G Sbjct: 253 YGGGGPGYSGGSRGYG--SGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGG 310 Query: 715 SYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQ 774 SY NYN NQS SN+GP Sbjct: 311 SYNDFGNYN------------------------------------NQS--SNFGP----M 328 Query: 775 KGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSG 824 KG N G S + P GGGG + N G GG S +SYGSG Sbjct: 329 KGGNFGGRS-------SGPYGGGGQ--YFAKPRNQGGYGGSSSSSSYGSG 369 Score = 69.7 bits (169), Expect = 1e-11 Identities = 67/245 (27%), Positives = 91/245 (37%), Gaps = 75/245 (30%) Query: 647 SIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGG-GG 705 S RGR FGG GG+ G ++G GGN F GG G+ GGG GG Sbjct: 192 SQRGRSGSGNFGGGRGGGF----GGNDNFGRGGN--------FSGRGGFGGSRGGGGYGG 239 Query: 706 GGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYS 765 G G +G+G+ GG YG G + G + Y Sbjct: 240 SGDGYNGFGN---------------------DGG-----YGGGGPGYSGGSRGY------ 267 Query: 766 NYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGG 825 G G Y N + GG G D +Y+ GG GG GSG Sbjct: 268 --------------GSGGQGYGNQGSGYGGSGSYD-------SYNNGGG--GGFGGGSGS 304 Query: 826 ASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSP--GSGQNYSGPPSSYQSSQGGYGR 883 GS+ +G + S++ +GG + P G GQ ++ P +QGGYG Sbjct: 305 NFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKP-----RNQGGYGG 359 Query: 884 NADHS 888 ++ S Sbjct: 360 SSSSS 364 Score = 49.7 bits (117), Expect = 1e-05 Identities = 41/127 (32%), Positives = 52/127 (40%), Gaps = 24/127 (18%) Query: 610 GGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGS----IRGRGRGRGFGGANHGGY 665 GGP ++ G+G GG + +G G GGS G G GFGG + G Sbjct: 256 GGPGYSGGSR--GYGSGGQGYGN-------QGSGYGGSGSYDSYNNGGGGGFGGGS-GSN 305 Query: 666 MNAGAGYGSYG-YGGNSATAGYSQFYSNGGHSGNASGGGG---------GGGGGSSGYGS 715 G Y +G Y S+ G + + GG S GGGG GG GGSS S Sbjct: 306 FGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSS 365 Query: 716 YYQGDNY 722 Y G + Sbjct: 366 YGSGRRF 372 Score = 38.5 bits (88), Expect = 0.028 Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 11/74 (14%) Query: 810 SGSGGRSGGNSYGSG-GASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYS 868 S GRSG ++G G G + + G GG G + G +GG Y G G N Sbjct: 191 SSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGG---GGYGGSGDGYNGF 247 Query: 869 GPPSSYQSSQGGYG 882 G + GGYG Sbjct: 248 G-------NDGGYG 254 >gi|109255251 loricrin [Homo sapiens] Length = 312 Score = 90.1 bits (222), Expect = 8e-18 Identities = 77/231 (33%), Positives = 98/231 (42%), Gaps = 40/231 (17%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNAS 700 G G GGS++ G G GG + G + + G G G + GG ++ G S +S+GG G +S Sbjct: 81 GGGSGGSVKYSGGGGSSGGGS-GCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG--GGSS 137 Query: 701 GGG------GGGG----------------GGSSGYGSYYQGDNYNSPVPPKHAGKKQPHG 738 GGG GGGG GGSSG GS ++G G Sbjct: 138 GGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCG 197 Query: 739 GQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGG 798 G GSGY S Q Q+ + +P +YG G + G G S ++S GGGG Sbjct: 198 GGSSGGSGSGYVSSQQVTQT-SCAPQPSYG-------GGSSGGGGSGGSGCFSSGGGGGS 249 Query: 799 SDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGK 849 S GS G G GG+ GS GG GGGS G S GK Sbjct: 250 SGCG-------GGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGK 293 Score = 87.4 bits (215), Expect = 5e-17 Identities = 85/256 (33%), Positives = 97/256 (37%), Gaps = 46/256 (17%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNAS 700 G G GG G G G GG + GG +G GY G GG YS GG G +S Sbjct: 22 GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYS--GGGG----------YSGGGCGGGSS 69 Query: 701 GGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYN 760 GGGGGGG G G GS G + GG GSG S G Sbjct: 70 GGGGGGGIGGCGGGS---------------GGSVKYSGGGGSSGGGSGCFSSGGGGSGCF 114 Query: 761 QSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSG--SGGRSGG 818 S G G ++ G G S S GGGG +Y G SGG SGG Sbjct: 115 SS--GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGG 172 Query: 819 NS--YGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGY------------SQSNYNSPGSG 864 S + SGG + + G G G GGGSS G GY Q +Y SG Sbjct: 173 GSGCFSSGGGGGSVCGYSGGGSGCGGGSS-GGSGSGYVSSQQVTQTSCAPQPSYGGGSSG 231 Query: 865 QNYSGPPSSYQSSQGG 880 SG + S GG Sbjct: 232 GGGSGGSGCFSSGGGG 247 Score = 87.4 bits (215), Expect = 5e-17 Identities = 82/249 (32%), Positives = 89/249 (35%), Gaps = 49/249 (19%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNAS 700 G G GG G G G G GG G G Y GG S+ G F S GG SG S Sbjct: 61 GGGCGGGSSGGGGGGGIGGCGGGS-----GGSVKYSGGGGSSGGGSGCFSSGGGGSGCFS 115 Query: 701 GGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYN 760 GGGG GG SG S G G S G G+ Q QSY Sbjct: 116 SGGGGSSGGGSGCFS-------------SGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYG 162 Query: 761 QSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNS 820 G G + G GS +S+ GGGGG S YSG G GG S Sbjct: 163 -----------GVSSGGSSGGGSGCFSS-----GGGGG------SVCGYSGGGSGCGGGS 200 Query: 821 YGSGGASY---------NPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPP 871 G G+ Y + YGGGS GG G S S G G SG Sbjct: 201 SGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIG 260 Query: 872 SSYQSSQGG 880 S S GG Sbjct: 261 SGCIISGGG 269 Score = 68.6 bits (166), Expect = 3e-11 Identities = 73/212 (34%), Positives = 85/212 (40%), Gaps = 43/212 (20%) Query: 691 SNGGHSGNASGGGG-------GGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKP 743 S GG G SGGGG G GGGSSG G Y G G GG Sbjct: 20 SGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSG------------GGGYSGGGCGGG 67 Query: 744 SYGSGYQSHQG--QQQSYNQSPYSNYGPPQGKQKG--YNHGQGSYSYSNSYNSPGGGGGS 799 S G G G S YS G G G + G GS +S+ GGG Sbjct: 68 SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127 Query: 800 DYNYESKFNYSGSGGRSGGNS--YGSGGASYNP-----GSHGGY--GGGSGGGSS-YQGK 849 ++ SG GG SGG S + SGG ++ S+GG GG SGGGS + Sbjct: 128 CFS-------SGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSG 180 Query: 850 QGGYSQSNYNSPGS---GQNYSGPPSSYQSSQ 878 GG S Y+ GS G + G S Y SSQ Sbjct: 181 GGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQ 212 Score = 60.5 bits (145), Expect = 7e-09 Identities = 55/194 (28%), Positives = 66/194 (34%), Gaps = 53/194 (27%) Query: 700 SGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSY 759 + GGGGGGGGS G G + G GG S GSG Sbjct: 19 TSGGGGGGGGSGGGGCGFFGG-----------------GGSGGGSSGSGC---------- 51 Query: 760 NQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN 819 GY+ G G S GGGGG G GG SGG+ Sbjct: 52 ----------------GYSGGGGYSGGGCGGGSSGGGGGG--------GIGGCGGGSGGS 87 Query: 820 SYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS--QSNYNSPGSGQNYSGPPSSYQSS 877 SGG + G G + G GG + GG S S S G G + G + S Sbjct: 88 VKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSG 147 Query: 878 QGGYGRNADHSMNY 891 GG+ A +Y Sbjct: 148 GGGFSGQAVQCQSY 161 Score = 57.0 bits (136), Expect = 8e-08 Identities = 49/134 (36%), Positives = 54/134 (40%), Gaps = 12/134 (8%) Query: 755 QQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGG 814 ++Q Q P G G G G + S GG GS Y YSG GG Sbjct: 5 KKQPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSG-GG 63 Query: 815 RSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSY 874 GG+S G GG G GG GGGSGG Y G GG S GSG SG S Sbjct: 64 CGGGSSGGGGG-----GGIGGCGGGSGGSVKYSG--GGGSSGG----GSGCFSSGGGGSG 112 Query: 875 QSSQGGYGRNADHS 888 S GG G + S Sbjct: 113 CFSSGGGGSSGGGS 126 Score = 43.1 bits (100), Expect = 0.001 Identities = 40/122 (32%), Positives = 46/122 (37%), Gaps = 37/122 (30%) Query: 643 GRGGSIRG-RGRGRGFGGANHGGYMNAGAGYGSY------------GYGGNSATAGYSQ- 688 G GGS+ G G G G GG + GG +G+GY S YGG S+ G S Sbjct: 181 GGGGSVCGYSGGGSGCGGGSSGG---SGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG 237 Query: 689 ---FYSNGGHSGNASGGG-----------------GGGGGGSSGYGSYYQGDNYNSPVPP 728 F S GG + GGG GGG G G GS G VP Sbjct: 238 SGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPI 297 Query: 729 KH 730 H Sbjct: 298 CH 299 Score = 35.4 bits (80), Expect = 0.24 Identities = 27/77 (35%), Positives = 30/77 (38%), Gaps = 5/77 (6%) Query: 634 PPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGS--YGYGGNSATAGYSQFYS 691 P P G GG G G GG G +G GS GG S G S S Sbjct: 221 PQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGS---S 277 Query: 692 NGGHSGNASGGGGGGGG 708 GG G++ GG G G G Sbjct: 278 GGGGGGSSVGGSGSGKG 294 >gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sapiens] Length = 378 Score = 84.7 bits (208), Expect = 3e-16 Identities = 75/214 (35%), Positives = 84/214 (39%), Gaps = 47/214 (21%) Query: 646 GSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGG 705 GS RGRG G G GG N G G G++G GGN G GG G + G GG Sbjct: 211 GSQRGRGGGSG-NFMGRGG--NFGGGGGNFGRGGNFGGRG-----GYGGGGGGSRGSYGG 262 Query: 706 GGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYS 765 G GG +G+G G NY GG G GY S G Y Sbjct: 263 GDGGYNGFGG--DGGNY---------------GG------GPGYSSRGG---------YG 290 Query: 766 NYGPPQGKQKGYNHGQGSYS-YSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSG 824 GP G Q G G G Y Y+ N GG G NY NYSG + G G Sbjct: 291 GGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGS 350 Query: 825 GASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNY 858 + GS G G GSGGGS GGY + Sbjct: 351 FGGRSSGSPYGGGYGSGGGS------GGYGSRRF 378 Score = 80.5 bits (197), Expect = 6e-15 Identities = 67/188 (35%), Positives = 82/188 (43%), Gaps = 43/188 (22%) Query: 624 GMGGPMHNEVPPPPNLRGRG----RGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGG 679 G GG N + N G G RGG+ GRG G GG + G Y GY G+GG Sbjct: 215 GRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYN--GFGG 272 Query: 680 NSATAGYSQFYSN-GGHSGNASGGG--GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQP 736 + G YS+ GG+ G G G GGG GG GY Y +G N+ Sbjct: 273 DGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFG------------- 319 Query: 737 HGGQQKPSYGSG-----YQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYS-YSNSY 790 GG +YG G + ++ GQQQ SNYGP +G G G+ S S Y Y Sbjct: 320 -GG----NYGGGGNYNDFGNYSGQQQ-------SNYGPMKGGSFG---GRSSGSPYGGGY 364 Query: 791 NSPGGGGG 798 S GG GG Sbjct: 365 GSGGGSGG 372 Score = 64.3 bits (155), Expect = 5e-10 Identities = 62/191 (32%), Positives = 74/191 (38%), Gaps = 61/191 (31%) Query: 693 GGHSGNASGGGG--GGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQ 750 GG SGN G GG GGGGG+ G G + G GG YG G Sbjct: 217 GGGSGNFMGRGGNFGGGGGNFGRGGNFGG-----------------RGG-----YGGGGG 254 Query: 751 SHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYS 810 +G +YG G G+ G+Y Y+S GG GG Sbjct: 255 GSRG-----------SYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGG------------ 291 Query: 811 GSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG- 869 GG YG+ G Y G GGY G + GG+ G GG NYN G NYSG Sbjct: 292 ------GGPGYGNQGGGYGGG--GGYDGYNEGGNFGGGNYGG--GGNYNDFG---NYSGQ 338 Query: 870 PPSSYQSSQGG 880 S+Y +GG Sbjct: 339 QQSNYGPMKGG 349 Score = 59.3 bits (142), Expect = 2e-08 Identities = 42/112 (37%), Positives = 52/112 (46%), Gaps = 19/112 (16%) Query: 772 GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPG 831 G Q+G G GS ++ + GGGGG N+ N+ G GG YG GG G Sbjct: 211 GSQRG--RGGGSGNFMGRGGNFGGGGG---NFGRGGNFGGRGG------YGGGGG----G 255 Query: 832 SHGGYGGGSGGGSSYQGKQGGYSQS-NYNSPGSGQNYSGPPSSYQSSQGGYG 882 S G YGGG GG + + G G Y Y+S G Y G Y + GGYG Sbjct: 256 SRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRG---GYGGGGPGYGNQGGGYG 304 Score = 55.1 bits (131), Expect = 3e-07 Identities = 44/107 (41%), Positives = 49/107 (45%), Gaps = 13/107 (12%) Query: 622 GFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAG-AGYGSYGYGGN 680 GFG G + P + G G GG G G GG + GY G G G+YG GGN Sbjct: 269 GFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGN 328 Query: 681 SATAG-YS-QFYSN----------GGHSGNASGGGGGGGGGSSGYGS 715 G YS Q SN G SG+ GGG G GGGS GYGS Sbjct: 329 YNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGS 375 Score = 51.6 bits (122), Expect = 3e-06 Identities = 36/109 (33%), Positives = 45/109 (41%), Gaps = 16/109 (14%) Query: 610 GGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAG 669 GGP ++++ G+G GGP + G G GG G G FGG N+GG G Sbjct: 279 GGPGYSSRG---GYGGGGPGYGNQGG-----GYGGGGGYDGYNEGGNFGGGNYGG----G 326 Query: 670 AGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGG--GGGGGGSSGYGSY 716 Y +G + Y GG G S G GGG G G G Y Sbjct: 327 GNYNDFGNYSGQQQSNYGPM--KGGSFGGRSSGSPYGGGYGSGGGSGGY 373 Score = 43.5 bits (101), Expect = 9e-04 Identities = 35/99 (35%), Positives = 41/99 (41%), Gaps = 19/99 (19%) Query: 801 YNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSG---------GGSSYQGKQG 851 +N E K S +S G+ G GG S N GG GG G GG G G Sbjct: 194 HNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGG 253 Query: 852 GYSQSNYNS--------PGSGQNYSGPPSSYQSSQGGYG 882 G S+ +Y G G NY G P SS+GGYG Sbjct: 254 GGSRGSYGGGDGGYNGFGGDGGNYGGGPG--YSSRGGYG 290 >gi|56699482 hypothetical protein LOC25940 [Homo sapiens] Length = 518 Score = 83.2 bits (204), Expect = 1e-15 Identities = 76/250 (30%), Positives = 90/250 (36%), Gaps = 53/250 (21%) Query: 626 GGPMHNEVPPP--PNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSAT 683 G P E PPP P + R G + GRG G GG H Y G G GG Sbjct: 307 GRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRG---GHEQGGGRGGR 363 Query: 684 AGYSQFYSNGG----HSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGG 739 GY GG H G + GG GGGGG YQ Y G Sbjct: 364 GGYDHGGRGGGRGNKHQGGWTDGGSGGGGG-------YQDGGYRD-------------SG 403 Query: 740 QQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGS 799 Q Y G+ S G Q G G G + S+SY G GG Sbjct: 404 FQPGGYHGGHSSG-------------------GYQGG---GYGGFQTSSSYTGSGYQGGG 441 Query: 800 DYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYN 859 Y ++++ G G GG G GG G G GGG GG S QGG + ++ Sbjct: 442 -YQQDNRYQDGGHHGDRGGGRGGRGGRG-GRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQ 499 Query: 860 SPGSGQNYSG 869 G N+SG Sbjct: 500 HGGYQYNHSG 509 Score = 63.9 bits (154), Expect = 6e-10 Identities = 54/162 (33%), Positives = 68/162 (41%), Gaps = 10/162 (6%) Query: 643 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGG 702 GRGG G GRG G G + GG+ + G+G G G +G+ +GGHS G Sbjct: 362 GRGGYDHG-GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQG 420 Query: 703 GGGGG--GGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQ-SHQGQQQSY 759 GG GG SS GS YQG Y + G GG + G G + GQ + Sbjct: 421 GGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGW 480 Query: 760 NQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDY 801 NY QG Q + G Y Y++S G G G Y Sbjct: 481 GGRGSQNY--HQGGQFEQHFQHGGYQYNHS----GFGQGRHY 516 Score = 58.9 bits (141), Expect = 2e-08 Identities = 43/113 (38%), Positives = 49/113 (43%), Gaps = 17/113 (15%) Query: 770 PQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYN 829 PQ + G G+G Y +S S GG GG + G GGR G + G GG N Sbjct: 329 PQQQTGGRGGGRGGYEHS----SYGGRGGHEQG-------GGRGGRGGYDHGGRGGGRGN 377 Query: 830 PGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 G GGSGGG YQ GGY S + G Y G SS GGYG Sbjct: 378 KHQGGWTDGGSGGGGGYQ--DGGYRDSGFQPGG----YHGGHSSGGYQGGGYG 424 Score = 51.2 bits (121), Expect = 4e-06 Identities = 51/175 (29%), Positives = 65/175 (37%), Gaps = 20/175 (11%) Query: 721 NYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHG 780 N P PP+ ++ G Q+ + G G + SY G +G + GY+HG Sbjct: 310 NEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHG 369 Query: 781 QGSYSYSNSYN-------SPGGGGGSDYNY-ESKFNYSG-SGGRSGGNSYGSG-GASYNP 830 N + S GGGG D Y +S F G GG S G G G G Sbjct: 370 GRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTS 429 Query: 831 GSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNA 885 S+ G G YQG GGY Q N G G + +GG G A Sbjct: 430 SSYTGSG--------YQG--GGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRA 474 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 82.8 bits (203), Expect = 1e-15 Identities = 75/203 (36%), Positives = 82/203 (40%), Gaps = 59/203 (29%) Query: 643 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGG 702 GRGGS G GRG G + G Y G+G G YGG S + G S GG G SG Sbjct: 477 GRGGS--GGSYGRGSRGGSGGSYGGGGSGGG---YGGGSGSRGGS-----GGSYGGGSGS 526 Query: 703 GGGGGGG-SSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQ 761 GGG GGG G G + G G H G +YG G S Sbjct: 527 GGGSGGGYGGGSGGGHSG------------GSGGGHSGGSGGNYGGGSGS---------- 564 Query: 762 SPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSY 821 G G +G GS S S S GGG SG GG SGG SY Sbjct: 565 ----------GGGSGGGYGGGSGSRGGSGGSHGGG-------------SGFGGESGG-SY 600 Query: 822 GSGGASYNPGSHGGYGGGSGGGS 844 G G + GS GGYGGGSG S Sbjct: 601 GGGEEA--SGSGGGYGGGSGKSS 621 Score = 82.4 bits (202), Expect = 2e-15 Identities = 65/191 (34%), Positives = 74/191 (38%), Gaps = 32/191 (16%) Query: 680 NSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYY-QGDNYNSPVPPKHAGKKQPHG 738 N G F S+G +G GG GG GGS G GS G +Y G Sbjct: 456 NLLEGGQEDFESSG--AGKIGLGGRGGSGGSYGRGSRGGSGGSYG--------------G 499 Query: 739 GQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGG 798 G YG G S G SY G G GY G G GG G Sbjct: 500 GGSGGGYGGGSGSRGGSGGSYG----GGSGSGGGSGGGYGGGSGG--------GHSGGSG 547 Query: 799 SDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNY 858 ++ S NY G G GG+ G GG S GS GG GG GGGS + G+ GG Sbjct: 548 GGHSGGSGGNYGGGSGSGGGSGGGYGGGS---GSRGGSGGSHGGGSGFGGESGGSYGGGE 604 Query: 859 NSPGSGQNYSG 869 + GSG Y G Sbjct: 605 EASGSGGGYGG 615 Score = 64.3 bits (155), Expect = 5e-10 Identities = 58/189 (30%), Positives = 69/189 (36%), Gaps = 56/189 (29%) Query: 665 YMNAGAGYGSYGYG-GNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYN 723 Y++ G G G G G S + YS+F S+GG GGGGG SSGYG Sbjct: 10 YLSRSGGGGGGGLGSGGSIRSSYSRFSSSGG------GGGGGRFSSSSGYGG-------- 55 Query: 724 SPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGS 783 GS +G S+ S Y G G Sbjct: 56 ----------------------GSSRVCGRGGGGSFGYS--------------YGGGSGG 79 Query: 784 YSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGG 843 ++S GGG + S YS SGG GG GSGG G GGYG G GG Sbjct: 80 GFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGG-----GFGGGYGSGFGGF 134 Query: 844 SSYQGKQGG 852 + G GG Sbjct: 135 GGFGGGAGG 143 Score = 63.9 bits (154), Expect = 6e-10 Identities = 42/99 (42%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 794 GGGGGSDYNYESKFNYSGSGGRSGGNSYG---SGGASYNPGSHGGYGGGSGGGSSYQGKQ 850 GG GGS +Y + + GSGG GG G GG+ GS G YGGGSG G G Sbjct: 476 GGRGGSGGSY-GRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGY 534 Query: 851 GGYSQSNY-------NSPGSGQNYSGPPSSYQSSQGGYG 882 GG S + +S GSG NY G S S GGYG Sbjct: 535 GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573 Score = 60.5 bits (145), Expect = 7e-09 Identities = 46/135 (34%), Positives = 58/135 (42%), Gaps = 11/135 (8%) Query: 753 QGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSY-----SYSNSYNSPGGGGGSDYNYESKF 807 +G Q+ + S G G ++G+GS SY + G GGGS S Sbjct: 459 EGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518 Query: 808 NYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 867 +Y G G GG+ G GG S G H GGSGGG S G G Y + + GSG Y Sbjct: 519 SYGGGSGSGGGSGGGYGGGS--GGGHS---GGSGGGHS-GGSGGNYGGGSGSGGGSGGGY 572 Query: 868 SGPPSSYQSSQGGYG 882 G S S G +G Sbjct: 573 GGGSGSRGGSGGSHG 587 Score = 60.1 bits (144), Expect = 9e-09 Identities = 60/171 (35%), Positives = 66/171 (38%), Gaps = 42/171 (24%) Query: 700 SGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSY 759 SGGGGGGG GS GG + SY S + S G Sbjct: 14 SGGGGGGGLGS---------------------------GGSIRSSY-SRFSSSGGGGGGG 45 Query: 760 NQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN 819 S S YG + G G GS+ YS Y GGG F+ S GG GG Sbjct: 46 RFSSSSGYGGGSSRVCGRGGG-GSFGYS--YGGGSGGG---------FSASSLGGGFGGG 93 Query: 820 SYGSGGASYNP-GSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSG 869 S G GGAS S GG+GGG GGGS G GGY G G G Sbjct: 94 SRGFGGASGGGYSSSGGFGGGFGGGSG-GGFGGGYGSGFGGFGGFGGGAGG 143 Score = 58.5 bits (140), Expect = 3e-08 Identities = 44/110 (40%), Positives = 54/110 (49%), Gaps = 19/110 (17%) Query: 610 GGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAG 669 GG +F++ + G+G G + GRG GGS G G G GG + G Sbjct: 43 GGGRFSS---SSGYGGGSS---------RVCGRGGGGSF-GYSYGGGSGGGFSASSLGGG 89 Query: 670 AGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQG 719 G GS G+GG S GYS S+GG G GG GGG GG GYGS + G Sbjct: 90 FGGGSRGFGGASG-GGYS---SSGGFGGGFGGGSGGGFGG--GYGSGFGG 133 Score = 56.6 bits (135), Expect = 1e-07 Identities = 40/107 (37%), Positives = 50/107 (46%), Gaps = 5/107 (4%) Query: 789 SYNSPGGGGGSDYNYESKFNYSGSGGRSG-GNSYGSGGASYNPGSHGG--YGGGSGGGSS 845 +Y++ GG D+ S G GGR G G SYG G + GS+GG GGG GGGS Sbjct: 453 TYHNLLEGGQEDFE-SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSG 511 Query: 846 YQGKQGG-YSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNY 891 +G GG Y + + GSG Y G S G G + NY Sbjct: 512 SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNY 558 Score = 55.1 bits (131), Expect = 3e-07 Identities = 45/119 (37%), Positives = 53/119 (44%), Gaps = 16/119 (13%) Query: 776 GYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSG----GRSGGNSYGSGGASYNPG 831 G G S + ++S GGGGG + S Y G GR GG GS G SY G Sbjct: 21 GLGSGGSIRSSYSRFSSSGGGGGGG-RFSSSSGYGGGSSRVCGRGGG---GSFGYSYGGG 76 Query: 832 SHGGY-----GGGSGGGSSYQG--KQGGYSQS-NYNSPGSGQNYSGPPSSYQSSQGGYG 882 S GG+ GGG GGGS G GGYS S + G + G Y S GG+G Sbjct: 77 SGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFG 135 Score = 53.5 bits (127), Expect = 8e-07 Identities = 42/114 (36%), Positives = 52/114 (45%), Gaps = 24/114 (21%) Query: 786 YSNSYNSP---GGG-----GGSDYNYESKFNYSGSGGRSG--GNSYGSGGASYNPGSHGG 835 +S+SY S GGG GGS + S+F+ SG GG G +S G GG S GG Sbjct: 6 FSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGG 65 Query: 836 -------YGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 YGGGSGGG S GG+ G + + G SS GG+G Sbjct: 66 GGSFGYSYGGGSGGGFSASSLGGGFG-------GGSRGFGGASGGGYSSSGGFG 112 Score = 53.5 bits (127), Expect = 8e-07 Identities = 56/200 (28%), Positives = 72/200 (36%), Gaps = 67/200 (33%) Query: 647 SIRGRGRGRGFGGANHGGYMNAG-AGYGSYGYGGNSATAGYSQFYSNGGHSGNASG--GG 703 S R G G GG GG + + + + S G GG G +F S+ G+ G +S G Sbjct: 9 SYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGG-----GGGRFSSSSGYGGGSSRVCGR 63 Query: 704 GGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSP 763 GGGG YG GG S G G+ Sbjct: 64 GGGGSFGYSYGG-------------------GSGGGFSASSLGGGF-------------- 90 Query: 764 YSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGS 823 G +G+ G Y+S GG GG G GG SGG G Sbjct: 91 -------GGGSRGFGGASG-----GGYSSSGGFGG------------GFGGGSGGGFGGG 126 Query: 824 GGASYNPGSHGGYGGGSGGG 843 G+ + G GG+GGG+GGG Sbjct: 127 YGSGF--GGFGGFGGGAGGG 144 Score = 50.8 bits (120), Expect = 5e-06 Identities = 34/75 (45%), Positives = 41/75 (54%), Gaps = 8/75 (10%) Query: 641 GRGRGGSIRGRGRG---RGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSG 697 G G S G G G RGFGGA+ GGY ++G G+G G+GG S G+ Y +G G Sbjct: 78 GGGFSASSLGGGFGGGSRGFGGASGGGYSSSG-GFGG-GFGGGSG-GGFGGGYGSG--FG 132 Query: 698 NASGGGGGGGGGSSG 712 G GGG GGG G Sbjct: 133 GFGGFGGGAGGGDGG 147 Score = 32.7 bits (73), Expect = 1.5 Identities = 22/68 (32%), Positives = 26/68 (38%), Gaps = 2/68 (2%) Query: 826 ASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNA 885 +SY S GG GGG G G S + +S S G G +S S GR Sbjct: 8 SSYLSRSGGGGGGGLGSGGSIRSSYSRFSSS--GGGGGGGRFSSSSGYGGGSSRVCGRGG 65 Query: 886 DHSMNYQY 893 S Y Y Sbjct: 66 GGSFGYSY 73 >gi|186928827 dermokine isoform 5 precursor [Homo sapiens] Length = 398 Score = 73.9 bits (180), Expect = 6e-13 Identities = 85/289 (29%), Positives = 115/289 (39%), Gaps = 38/289 (13%) Query: 621 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-NHGGYMNAGAGYGSYGYGG 679 PGFG + N V + G G GR HG G+ G G+ G Sbjct: 87 PGFGAADALGNRVGEAAHALGN------TGHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140 Query: 680 NSATAG-YSQFYSNGGHSGNASGGGGGGG--------GGSSG-YGSYYQGDNYN---SPV 726 T+G + F S GG G G GG G G S+G +G QG + + Sbjct: 141 AWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200 Query: 727 PPKHAGKKQPHGGQQKPSYGSGYQSHQGQ-----QQSYNQSPYSNYGPPQGKQKGYNHGQ 781 PP Q G +P YGS S+Q + S + SN G G Q G + G Sbjct: 201 PPNFGTNTQ--GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGS 257 Query: 782 GSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSG 841 GS +N+ +S GG + S SGG SGG+S SGG+ + GS +G +G Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGS------SGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311 Query: 842 GGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSS-QGGYGRNADHSM 889 S G GG N + PG + + S +S QG G+ +M Sbjct: 312 SSS---GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM 357 >gi|186928825 dermokine isoform 3 precursor [Homo sapiens] Length = 416 Score = 73.9 bits (180), Expect = 6e-13 Identities = 85/289 (29%), Positives = 115/289 (39%), Gaps = 38/289 (13%) Query: 621 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-NHGGYMNAGAGYGSYGYGG 679 PGFG + N V + G G GR HG G+ G G+ G Sbjct: 87 PGFGAADALGNRVGEAAHALGN------TGHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140 Query: 680 NSATAG-YSQFYSNGGHSGNASGGGGGGG--------GGSSG-YGSYYQGDNYN---SPV 726 T+G + F S GG G G GG G G S+G +G QG + + Sbjct: 141 AWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200 Query: 727 PPKHAGKKQPHGGQQKPSYGSGYQSHQGQ-----QQSYNQSPYSNYGPPQGKQKGYNHGQ 781 PP Q G +P YGS S+Q + S + SN G G Q G + G Sbjct: 201 PPNFGTNTQ--GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGS 257 Query: 782 GSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSG 841 GS +N+ +S GG + S SGG SGG+S SGG+ + GS +G +G Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGS------SGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311 Query: 842 GGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSS-QGGYGRNADHSM 889 S G GG N + PG + + S +S QG G+ +M Sbjct: 312 SSS---GNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNM 357 Score = 57.4 bits (137), Expect = 6e-08 Identities = 68/252 (26%), Positives = 89/252 (35%), Gaps = 37/252 (14%) Query: 620 NPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGA--------- 670 NPG G+G P + P GS +G +G +GG N G Sbjct: 164 NPG-GLGTPWVHGYPG-------NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215 Query: 671 GYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKH 730 GYGS + +GG S N SGGG G GSSG GS GDN N Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSN-SGGGSGSQSGSSGSGS--NGDNNNGSSSGGS 272 Query: 731 AGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSY 790 + G S GS S + S ++S ++G G G NHG Sbjct: 273 SSGSSSGGSSGGSSGGSSGNSGGSRGDSGSES---SWGSSTGSSSG-NHG---------- 318 Query: 791 NSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGG--SGGGSSYQG 848 GGG G E N + G SG + G S N G G G +Y+ Sbjct: 319 -GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRN 377 Query: 849 KQGGYSQSNYNS 860 + N+++ Sbjct: 378 SETSPGMFNFDT 389 >gi|186928829 dermokine isoform 4 precursor [Homo sapiens] Length = 386 Score = 73.6 bits (179), Expect = 8e-13 Identities = 84/283 (29%), Positives = 113/283 (39%), Gaps = 37/283 (13%) Query: 621 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-NHGGYMNAGAGYGSYGYGG 679 PGFG + N V + G G GR HG G+ G G+ G Sbjct: 87 PGFGAADALGNRVGEAAHALGN------TGHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140 Query: 680 NSATAG-YSQFYSNGGHSGNASGGGGGGG--------GGSSG-YGSYYQGDNYN---SPV 726 T+G + F S GG G G GG G G S+G +G QG + + Sbjct: 141 AWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200 Query: 727 PPKHAGKKQPHGGQQKPSYGSGYQSHQGQ-----QQSYNQSPYSNYGPPQGKQKGYNHGQ 781 PP Q G +P YGS S+Q + S + SN G G Q G + G Sbjct: 201 PPNFGTNTQ--GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGS 257 Query: 782 GSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSG 841 GS +N+ +S GG + S SGG SGG+S SGG+ + GS +G +G Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGS------SGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311 Query: 842 GGSSYQGKQGGYS--QSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 S G GG + + PG+ SG S Q+S+ G Sbjct: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSG-ESGIQNSETSPG 353 Score = 44.3 bits (103), Expect = 5e-04 Identities = 50/160 (31%), Positives = 59/160 (36%), Gaps = 16/160 (10%) Query: 737 HGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGG 796 H G + S G G QG Q G P GY N +P G Sbjct: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPW--VHGYPGNSAGSFGMNPQGAPWGQ 195 Query: 797 GGSDYNYESKFNYSGSGGRSGGNSYGSGGASY------NPGSHGGYGGG--SGGGSSYQG 848 GG+ N G+ + G YGS AS NP G GG SGGGS G Sbjct: 196 GGNGGPPNFGTNTQGAVAQPG---YGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS---G 249 Query: 849 KQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHS 888 Q G S S N + + SG SS SS G G ++ S Sbjct: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289 >gi|33504489 dermokine isoform 2 precursor [Homo sapiens] Length = 476 Score = 73.6 bits (179), Expect = 8e-13 Identities = 84/283 (29%), Positives = 113/283 (39%), Gaps = 37/283 (13%) Query: 621 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-NHGGYMNAGAGYGSYGYGG 679 PGFG + N V + G G GR HG G+ G G+ G Sbjct: 87 PGFGAADALGNRVGEAAHALGN------TGHEIGRQAEDVIRHGADAVRGSWQGVPGHNG 140 Query: 680 NSATAG-YSQFYSNGGHSGNASGGGGGGG--------GGSSG-YGSYYQGDNYN---SPV 726 T+G + F S GG G G GG G G S+G +G QG + + Sbjct: 141 AWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200 Query: 727 PPKHAGKKQPHGGQQKPSYGSGYQSHQGQ-----QQSYNQSPYSNYGPPQGKQKGYNHGQ 781 PP Q G +P YGS S+Q + S + SN G G Q G + G Sbjct: 201 PPNFGTNTQ--GAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG-SSGS 257 Query: 782 GSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSG 841 GS +N+ +S GG + S SGG SGG+S SGG+ + GS +G +G Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGS------SGGSSGGSSGNSGGSRGDSGSESSWGSSTG 311 Query: 842 GGSSYQGKQGGYS--QSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 S G GG + + PG+ SG S Q+S+ G Sbjct: 312 SSSGNHGGSGGGNGHKPGCEKPGNEARGSG-ESGIQNSETSPG 353 Score = 44.3 bits (103), Expect = 5e-04 Identities = 50/160 (31%), Positives = 59/160 (36%), Gaps = 16/160 (10%) Query: 737 HGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGG 796 H G + S G G QG Q G P GY N +P G Sbjct: 138 HNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPW--VHGYPGNSAGSFGMNPQGAPWGQ 195 Query: 797 GGSDYNYESKFNYSGSGGRSGGNSYGSGGASY------NPGSHGGYGGG--SGGGSSYQG 848 GG+ N G+ + G YGS AS NP G GG SGGGS G Sbjct: 196 GGNGGPPNFGTNTQGAVAQPG---YGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS---G 249 Query: 849 KQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHS 888 Q G S S N + + SG SS SS G G ++ S Sbjct: 250 SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGS 289 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 73.2 bits (178), Expect = 1e-12 Identities = 51/118 (43%), Positives = 62/118 (52%), Gaps = 15/118 (12%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYG--YGGNSATAGYSQFYSNGGHSGN 698 G GG G G G G GG++ GGY +G GS G YGG S++ G+ S+GG+ G Sbjct: 475 GGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGS-SSGGYGGG 533 Query: 699 ASGGGGGG-GGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGS-GYQSHQG 754 +SGGGGGG GGGSSG GS G Y G GG + S GS G S +G Sbjct: 534 SSGGGGGGYGGGSSGGGS-SSGGGY---------GGGSSSGGHKSSSSGSVGESSSKG 581 Score = 67.8 bits (164), Expect = 4e-11 Identities = 61/174 (35%), Positives = 65/174 (37%), Gaps = 47/174 (27%) Query: 697 GNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQ 756 G S GGGG GGGS G G Y G + H G HGG YG G Sbjct: 455 GEGSSGGGGRGGGSFG-GGYGGGSSGGGSSGGGHGGG---HGGSSGGGYGGGSSG----- 505 Query: 757 QSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRS 816 G G +G GS S GG GGS SGG Sbjct: 506 ---------------GGSSGGGYGGGS--------SSGGHGGSS-----------SGGYG 531 Query: 817 GGNSYGSGGASYNPGSHGG---YGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNY 867 GG+S G GG Y GS GG GGG GGGSS G + S S S G Y Sbjct: 532 GGSS-GGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584 Score = 66.6 bits (161), Expect = 1e-10 Identities = 64/212 (30%), Positives = 73/212 (34%), Gaps = 86/212 (40%) Query: 652 GRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGG--GGG 709 G G GG GG + G GYG GG S+ G+ GGH G++ GG GGG GGG Sbjct: 455 GEGSSGGGGRGGG--SFGGGYGGGSSGGGSSGGGH-----GGGHGGSSGGGYGGGSSGGG 507 Query: 710 SSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGP 769 SSG G Y G + HGG YG G Sbjct: 508 SSG-GGYGGGSSSGG------------HGGSSSGGYGGG--------------------- 533 Query: 770 PQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYN 829 S GGGGG G GG S G GG+S Sbjct: 534 ----------------------SSGGGGG------------GYGGGSSG-----GGSS-- 552 Query: 830 PGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSP 861 S GGYGGGS G G +S+ P Sbjct: 553 --SGGGYGGGSSSGGHKSSSSGSVGESSSKGP 582 Score = 61.6 bits (148), Expect = 3e-09 Identities = 46/126 (36%), Positives = 54/126 (42%), Gaps = 9/126 (7%) Query: 772 GKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSG--SGGRSGGNSYGSGGASYN 829 G + G + G G S+ S GGG G + S Y G SGG S G YG G +S Sbjct: 462 GGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSS-- 519 Query: 830 PGSHGGYGGGSGGGSSYQGKQGGY-SQSNYNSPGSGQNYSGPPSS---YQSSQGGYGRNA 885 G HGG G GG S G GGY S+ SG Y G SS SS G G ++ Sbjct: 520 -GGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESS 578 Query: 886 DHSMNY 891 Y Sbjct: 579 SKGPRY 584 Score = 60.8 bits (146), Expect = 5e-09 Identities = 64/216 (29%), Positives = 78/216 (36%), Gaps = 55/216 (25%) Query: 690 YSNGGH-SGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSG 748 YS+ H S + SGGGGGGGG G G K S G G Sbjct: 5 YSSSKHYSSSRSGGGGGGGGCGGG------------------GGVSSLRISSSKGSLGGG 46 Query: 749 YQSHQGQQQSYNQSPYSNYGPPQGKQKGYN--HGQGSYSYSNSYNSPGGGGGSDYNYESK 806 + S S+++ S G G GY G G S+ SY S GG +Y Sbjct: 47 FSSGGFSGGSFSRGS-SGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGG----SYGGS 101 Query: 807 FNYSGSGGRS-GGNSYGSGGASYNPGSHGGYGGGSGGG-------------------SSY 846 F GG S GG S+G GG G GG+GGG GG +SY Sbjct: 102 FGGGSFGGGSFGGGSFGGGGFG-GGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASY 160 Query: 847 QGKQGGYSQSNYNSPGS--------GQNYSGPPSSY 874 K +SNY G G ++ G P Y Sbjct: 161 LDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDY 196 Score = 59.3 bits (142), Expect = 2e-08 Identities = 36/91 (39%), Positives = 42/91 (46%), Gaps = 5/91 (5%) Query: 792 SPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQG 851 S GGGG ++ + SGG S G +G G + S GGYGGGS GG S G G Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGG---HGGSSGGGYGGGSSGGGSSGGGYG 514 Query: 852 GYSQSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 G S S + S Y G S GGYG Sbjct: 515 GGSSSGGHGGSSSGGYGGGSSG--GGGGGYG 543 Score = 58.5 bits (140), Expect = 3e-08 Identities = 40/113 (35%), Positives = 47/113 (41%), Gaps = 7/113 (6%) Query: 641 GRGRGGSIRGRGRGRGF--GGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGN 698 G GRGG G G G G GG++ GG+ G GYGG S+ G S+GG G Sbjct: 461 GGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG-----SSGGGYGG 515 Query: 699 ASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQS 751 S GG GG S GYG G G GG S G++S Sbjct: 516 GSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKS 568 Score = 53.1 bits (126), Expect = 1e-06 Identities = 37/103 (35%), Positives = 45/103 (43%), Gaps = 4/103 (3%) Query: 784 YSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGG--NSYGSGGASYNPGSHGG--YGGG 839 YS S S GGGG S S S G GG +S G G S++ GS GG +GG Sbjct: 11 YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS 70 Query: 840 SGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 SGG G GG + +Y S G +Y G G +G Sbjct: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFG 113 Score = 52.4 bits (124), Expect = 2e-06 Identities = 32/82 (39%), Positives = 38/82 (46%), Gaps = 8/82 (9%) Query: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNAS 700 G GG G G GG++ GGY +G G GYGG S+ G S S GG+ G +S Sbjct: 506 GGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSS---SGGGYGGGSS 562 Query: 701 GGG-----GGGGGGSSGYGSYY 717 GG G G SS G Y Sbjct: 563 SGGHKSSSSGSVGESSSKGPRY 584 Score = 49.3 bits (116), Expect = 2e-05 Identities = 33/78 (42%), Positives = 40/78 (51%), Gaps = 9/78 (11%) Query: 645 GGSIRGRGRGRGFGGANHGGYMNAGAGYGSYG--YGGNSATAGYSQFYSNGGHSGNASGG 702 GGS G G GFGG + G + + GSYG +GG S G S GG G+ GG Sbjct: 68 GGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGG-----SFGG--GSFGGG 120 Query: 703 GGGGGGGSSGYGSYYQGD 720 G GGGG G+G + GD Sbjct: 121 GFGGGGFGGGFGGGFGGD 138 Score = 48.5 bits (114), Expect = 3e-05 Identities = 33/81 (40%), Positives = 41/81 (50%), Gaps = 7/81 (8%) Query: 645 GGSI-RGRGRGRGFGGANHGGYMNAGA-GYGSY--GYGGNSATAGYSQFYSNGGHSGNAS 700 GGS RG G FGG++ GGY G G GS+ YG +S Y + G G + Sbjct: 54 GGSFSRGSSGGGCFGGSS-GGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSF 112 Query: 701 GGG--GGGGGGSSGYGSYYQG 719 GGG GGGG G G+G + G Sbjct: 113 GGGSFGGGGFGGGGFGGGFGG 133 Score = 46.6 bits (109), Expect = 1e-04 Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 10/122 (8%) Query: 645 GGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGG 704 GGS RG FGG+ G + G GS+G GG+ G+ GG G GG G Sbjct: 82 GGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFG-GGSFGGGGFG----GGGFGGGFGGGFG 136 Query: 705 GGGGGSSGYGSYYQ---GDNYNSPVPPKHAGKKQPH--GGQQKPSYGSGYQSHQGQQQSY 759 G GG SG D S + A ++ + G+ K Y SHQG+ + Y Sbjct: 137 GDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDY 196 Query: 760 NQ 761 ++ Sbjct: 197 SK 198 Score = 44.3 bits (103), Expect = 5e-04 Identities = 42/125 (33%), Positives = 50/125 (40%), Gaps = 25/125 (20%) Query: 783 SYSYSNSYNSPGGGGG--------SDYNYESKFNYSGSGGRSGGNSYGS----------- 823 S YS+S + GGGGG S S G G SGG S GS Sbjct: 8 SKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCF 67 Query: 824 GGASYNPGSHGGYGGG----SGGGSSYQGKQGGYSQSNYNSPGS--GQNYSGPPSSYQSS 877 GG+S G GG+GGG S G SS+ G GG GS G ++ G Sbjct: 68 GGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGF 127 Query: 878 QGGYG 882 GG+G Sbjct: 128 GGGFG 132 Score = 36.2 bits (82), Expect = 0.14 Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 22/99 (22%) Query: 784 YSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGG 843 YS S Y+S GGG G GG GG S S + GS GGG Sbjct: 5 YSSSKHYSSSRSGGGG-----------GGGGCGGGGGVSSLRISSSKGS-------LGGG 46 Query: 844 SSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYG 882 S GG+S +++ SG G S GG+G Sbjct: 47 FS----SGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFG 81 Score = 35.0 bits (79), Expect = 0.31 Identities = 28/81 (34%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 638 NLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYG--SYGYGGNSATAGYSQFYSNGGH 695 +LR GS+ G GF G + + G +G S GYGG G S S G Sbjct: 33 SLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSS 92 Query: 696 SGNASGGGGGGGG--GSSGYG 714 S S GG GGG G +G Sbjct: 93 SFGGSYGGSFGGGSFGGGSFG 113 >gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo sapiens] Length = 940 Score = 72.4 bits (176), Expect = 2e-12 Identities = 83/279 (29%), Positives = 103/279 (36%), Gaps = 53/279 (18%) Query: 607 PVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGF-GGANHGGY 665 P GGP PH G GP PPPP RGG G G GG GG Sbjct: 645 PGPGGPM--PGPHGGPGGPVGPRLLGPPPPP------RGGDPFWDGPGDPMRGGPMRGG- 695 Query: 666 MNAGAGYGSY-----GYGGNSATAGYSQFY-SNGGHSGNASGGGGGG-GGGSSGYGSY-- 716 G G G Y G GGN F + GG SG G GG GGG G G + Sbjct: 696 --PGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRP 753 Query: 717 YQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKG 776 ++G H + P GG GSG++ H+G S + P +G G Sbjct: 754 HEGPGGGMGNSSGHRPHEGPGGGM-----GSGHRPHEGPGGSMGGG--GGHRPHEGPGGG 806 Query: 777 YNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGN----SYGSGGASYN--- 829 + G G + PGGG G+ + GS G SGG+ G GG + Sbjct: 807 ISGGSGH----RPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPH 862 Query: 830 --------------PGSHGGYGGGSGGGSSYQGKQGGYS 854 P H G+ G GG ++G GG+S Sbjct: 863 DVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHS 901 Score = 64.3 bits (155), Expect = 5e-10 Identities = 75/273 (27%), Positives = 95/273 (34%), Gaps = 35/273 (12%) Query: 627 GPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGY 686 GP+ N PP G GG + G GG G + G G G G Sbjct: 623 GPIANGFPPG------GPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGG 676 Query: 687 SQFYSNGGHS--GNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPS 744 F+ G G GG G G G G +G N P PP G + G P+ Sbjct: 677 DPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPN 736 Query: 745 Y----------GSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPG 794 G G++ H+G S S + P +G G G G + S G Sbjct: 737 GRGGPGGGMVGGGGHRPHEGPGGGMGNS--SGHRPHEGPGGGM--GSGHRPHEGPGGSMG 792 Query: 795 GGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYS 854 GGGG + G GG S GSG + G GG G G GG ++G G Sbjct: 793 GGGG----------HRPHEGPGGGISGGSGHRPHE-GPGGGMGAG-GGHRPHEGPGGSMG 840 Query: 855 QSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADH 887 S + P G + GP G+ R DH Sbjct: 841 GSGGHRPHEGPGHGGPHGHRPHDVPGH-RGHDH 872 Score = 32.3 bits (72), Expect = 2.0 Identities = 55/247 (22%), Positives = 73/247 (29%), Gaps = 48/247 (19%) Query: 669 GAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPP 728 G+G G GG+ + + G G GGGG S N + P Sbjct: 541 GSGGSPDGAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIMGSPNSH----P 596 Query: 729 KHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPP--QGKQKGYNH---GQGS 783 KQ P Y + P +N PP G KG H G G Sbjct: 597 SEELLKQ-------PDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGG 649 Query: 784 YSYSNSYNSPGG-------------GGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNP 830 + PGG GG + + G G G GG P Sbjct: 650 -PMPGPHGGPGGPVGPRLLGPPPPPRGGDPF-------WDGPGDPMRGGPM-RGGPGPGP 700 Query: 831 GSHGGYGGGSGGG----------SSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGG 880 G + GG GG + G+ GG + PG G G ++ GG Sbjct: 701 GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGG 760 Query: 881 YGRNADH 887 G ++ H Sbjct: 761 MGNSSGH 767 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.131 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,949,891 Number of Sequences: 37866 Number of extensions: 2481214 Number of successful extensions: 36332 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 341 Number of HSP's successfully gapped in prelim test: 560 Number of HSP's that attempted gapping in prelim test: 14368 Number of HSP's gapped (non-prelim): 7855 length of query: 894 length of database: 18,247,518 effective HSP length: 111 effective length of query: 783 effective length of database: 14,044,392 effective search space: 10996758936 effective search space used: 10996758936 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.