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Search of human proteins with 239757832
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757832 PREDICTED: hypothetical protein [Homo sapiens]
(503 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757832 PREDICTED: hypothetical protein [Homo sapiens] 1039 0.0
gi|239752343 PREDICTED: hypothetical protein [Homo sapiens] 1012 0.0
gi|239746856 PREDICTED: hypothetical protein XP_002343859 [Homo ... 1012 0.0
gi|223468693 hypothetical protein LOC100130361 [Homo sapiens] 681 0.0
gi|223468690 hypothetical protein LOC100132994 [Homo sapiens] 681 0.0
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 57 4e-08
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 57 4e-08
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 55 1e-07
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 55 1e-07
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 55 1e-07
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 55 2e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 54 3e-07
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 54 3e-07
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 54 3e-07
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 49 1e-05
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 49 1e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 48 2e-05
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 47 5e-05
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 46 7e-05
gi|27262667 colony stimulating factor 1 isoform a precursor [Hom... 45 1e-04
gi|27262661 colony stimulating factor 1 isoform a precursor [Hom... 45 1e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 45 2e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 45 2e-04
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 45 2e-04
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 45 2e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 45 2e-04
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 43 6e-04
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 42 0.001
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 42 0.001
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 42 0.001
>gi|239757832 PREDICTED: hypothetical protein [Homo sapiens]
Length = 503
Score = 1039 bits (2687), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60
MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT
Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60
Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120
DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG
Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120
Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180
HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER
Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240
GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP
Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240
Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300
GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV
Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300
Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP
Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL
Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ
Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
Query: 481 QPPGAQGCPRVMLCVAPRNRGPH 503
QPPGAQGCPRVMLCVAPRNRGPH
Sbjct: 481 QPPGAQGCPRVMLCVAPRNRGPH 503
>gi|239752343 PREDICTED: hypothetical protein [Homo sapiens]
Length = 518
Score = 1012 bits (2617), Expect = 0.0
Identities = 491/493 (99%), Positives = 492/493 (99%)
Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60
MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT
Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60
Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120
DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG
Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120
Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180
HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER
Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240
GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP
Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240
Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300
GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV
Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300
Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP
Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL
Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ
Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
Query: 481 QPPGAQGCPRVML 493
QPPGAQGCPR +L
Sbjct: 481 QPPGAQGCPRCIL 493
>gi|239746856 PREDICTED: hypothetical protein XP_002343859 [Homo
sapiens]
Length = 518
Score = 1012 bits (2617), Expect = 0.0
Identities = 491/493 (99%), Positives = 492/493 (99%)
Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60
MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT
Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60
Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120
DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG
Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120
Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180
HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER
Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240
GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP
Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240
Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300
GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV
Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300
Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP
Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL
Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ
Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
Query: 481 QPPGAQGCPRVML 493
QPPGAQGCPR +L
Sbjct: 481 QPPGAQGCPRCIL 493
>gi|223468693 hypothetical protein LOC100130361 [Homo sapiens]
Length = 514
Score = 681 bits (1756), Expect = 0.0
Identities = 348/490 (71%), Positives = 382/490 (77%), Gaps = 4/490 (0%)
Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60
MSS D+VSVC AG EGG++AG+ TASPGAP HG DL G G GK ESGFT
Sbjct: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56
Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120
DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ DYSFYLADEPA I+PP SVQG
Sbjct: 57 DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116
Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180
HP PEGA A+GS + WAD EVGPS R L SPG+WQQASAG LHL PGP AW+NPER
Sbjct: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240
GSKSR S +VDPQQPSA+GP L T DSDSADESSDLP+++V I EGSQAKPGSPKK
Sbjct: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236
Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300
DT + SFH +ESYL V G L S PR LTPV ERPAVGEL+ KKMQS WGK V
Sbjct: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296
Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
RPSCSGAA G LP+G RK+A KKSL GA +LAL FPA G+RLSA PP+PA+FPP
Sbjct: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356
Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
SGV G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L
Sbjct: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416
Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
LSVRRGE+SS DPNIRAPQ+ GTS+PSA++ LVPR HA SG+ QPPVHPPRPERQQ
Sbjct: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476
Query: 481 QPPGAQGCPR 490
QPPGAQGCPR
Sbjct: 477 QPPGAQGCPR 486
>gi|223468690 hypothetical protein LOC100132994 [Homo sapiens]
Length = 514
Score = 681 bits (1756), Expect = 0.0
Identities = 348/490 (71%), Positives = 382/490 (77%), Gaps = 4/490 (0%)
Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60
MSS D+VSVC AG EGG++AG+ TASPGAP HG DL G G GK ESGFT
Sbjct: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56
Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120
DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ DYSFYLADEPA I+PP SVQG
Sbjct: 57 DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116
Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180
HP PEGA A+GS + WAD EVGPS R L SPG+WQQASAG LHL PGP AW+NPER
Sbjct: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240
GSKSR S +VDPQQPSA+GP L T DSDSADESSDLP+++V I EGSQAKPGSPKK
Sbjct: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236
Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300
DT + SFH +ESYL V G L S PR LTPV ERPAVGEL+ KKMQS WGK V
Sbjct: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296
Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
RPSCSGAA G LP+G RK+A KKSL GA +LAL FPA G+RLSA PP+PA+FPP
Sbjct: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356
Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
SGV G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L
Sbjct: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416
Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
LSVRRGE+SS DPNIRAPQ+ GTS+PSA++ LVPR HA SG+ QPPVHPPRPERQQ
Sbjct: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476
Query: 481 QPPGAQGCPR 490
QPPGAQGCPR
Sbjct: 477 QPPGAQGCPR 486
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 57.0 bits (136), Expect = 4e-08
Identities = 123/494 (24%), Positives = 165/494 (33%), Gaps = 106/494 (21%)
Query: 15 GPEG--GEQAGAHTASPGAPRGD-GHGRDLNFGGQR--SGKGKGKGESGFTDPESFSFES 69
GP+G GE+ + A P GD G + G R +G+ G G P
Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP--- 581
Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129
G++GRPG P A G V G P P+GA
Sbjct: 582 -------------GEDGRPGPPGPQGARG----------------QPGVMGFPGPKGANG 612
Query: 130 KGSTDIWADLEVGPSWRGALSPSPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187
+ L P RG PG + + +AGP PGP GPA E E+G+
Sbjct: 613 EPGKAGEKGLPGAPGLRGL----PGKDGETGAAGP-----PGPAGPAGERGEQGAPGPSG 663
Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG--DTCG 245
FQ P P G G K G Q PG PG G
Sbjct: 664 FQGLPGPPGPPGEGG------------------------KPGDQGVPGEAGAPGLVGPRG 699
Query: 246 RRSFHRRESYLQVQGPLLISPPRRL--TPVVERP--AVGELDVPSLKKMQSMVWGKRGVR 301
R F QG + PR L TP + P A G P + G +G+
Sbjct: 700 ERGFPGERGSPGAQG---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP----GLQGMP 752
Query: 302 PSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL----ALRGAFPAWGQRLSAVPPDPA 356
A + GP RG +G K + +G L G A G++ PP PA
Sbjct: 753 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 812
Query: 357 SFPPVSGV-GLLGKSVRPKEPKHSSP--GKKPAGRKTRESQAAAREDNDPNRDEVPRAQL 413
G G G++ P + P G K + +A + D + P
Sbjct: 813 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 872
Query: 414 PTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHP 473
Q P ++ + + G P T P A R+ P S+G+ PP P
Sbjct: 873 GPQGPTGVT-GPKGARGAQGPPG-------ATGFPGA--AGRVGP--PGSNGNPGPP-GP 919
Query: 474 PRPERQQQPPGAQG 487
P P + P GA+G
Sbjct: 920 PGPSGKDGPKGARG 933
Score = 37.4 bits (85), Expect = 0.032
Identities = 121/493 (24%), Positives = 156/493 (31%), Gaps = 86/493 (17%)
Query: 15 GPEG-----GEQAGAHTASPGAPRGD-GHGRDLNFGGQRSGKGKGKGESGFTDPESFSFE 68
GP G GE+ A A P RGD G G+ G+G G G P + E
Sbjct: 744 GPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIGPPGPAGANGE 802
Query: 69 SESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGAT 128
+ E+ G G G PG + G PA P G P +G
Sbjct: 803 -KGEVGPPGPAGSAGARGAPGERGETGPPG----------PAGFAGPPGADGQPGAKGEQ 851
Query: 129 AKGST--DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVP-----GPGPAWENPERG 181
+ D A GPS GA P GP ++ P GP G
Sbjct: 852 GEAGQKGDAGAPGPQGPS--GAPGPQ---------GPTGVTGPKGARGAQGPPGATGFPG 900
Query: 182 SKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241
+ R+ P GP G + D P R +G PG +PG
Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG 960
Query: 242 DTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMVWGKRGV 300
D + +GP +V P GE P L S GK+G
Sbjct: 961 D----------DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-PSGEPGKQGA 1009
Query: 301 RPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359
P SG RGP P G G + EG+P + PP
Sbjct: 1010 -PGASGD--RGPPGPVGPPGLTGPAGEPGREGSPG--------------ADGPPGRDGAA 1052
Query: 360 PVSG----VGLLGKSVRPKEPKHSSPGKK-PAGRKTRESQAAAREDNDPNRDEVPRAQLP 414
V G G +G P P SPG P G++ +A A+ P+ R
Sbjct: 1053 GVKGDRGETGAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1110
Query: 415 TQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPP 474
Q P R + +G+P R G FT + +P SGD Q P
Sbjct: 1111 PQGP-------RGDKGEAGEPGER-----GLKGHRGFTGLQGLPGPPGPSGD-QGASGPA 1157
Query: 475 RPERQQQPPGAQG 487
P + PPG G
Sbjct: 1158 GPSGPRGPPGPVG 1170
Score = 35.4 bits (80), Expect = 0.12
Identities = 67/271 (24%), Positives = 87/271 (32%), Gaps = 26/271 (9%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70
R GP G G P +G+ G SGK KG G + P + E
Sbjct: 887 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP-SGKDGPKGARGDSGPPGRAGEPG 945
Query: 71 SELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSS-----VQGHPSPE 125
QG G++G PG A G LA + + P G P P
Sbjct: 946 L----QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001
Query: 126 GATAK-----GSTDIWADLEVGPSWRGALSPSPG-EWQQASAGPLHLSVPG-PGPAWENP 178
G K S D VGP + PG E + GP PG G A
Sbjct: 1002 GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PGRDGAAGVKG 1056
Query: 179 ERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPK 238
+RG + P P + GPAG D + + P+ + G Q G
Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116
Query: 239 KPGDT--CGRRSFHRRESYLQVQGPLLISPP 267
G+ G R + +QG L PP
Sbjct: 1117 DKGEAGEPGERGLKGHRGFTGLQG--LPGPP 1145
Score = 35.0 bits (79), Expect = 0.16
Identities = 46/170 (27%), Positives = 58/170 (34%), Gaps = 24/170 (14%)
Query: 83 GQEGRPGTPVDDQAGGGDYSFYLADE---------PATIMPPSSVQGHPSPEGATAKGST 133
G+ GR G+P D G D + + + P PP G P P G T K
Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPP----GSPGPAGPTGKQGD 1087
Query: 134 --DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVD 191
+ A +GPS P+ Q GP G A E ERG K F
Sbjct: 1088 RGEAGAQGPMGPS-----GPAGARGIQGPQGPRG----DKGEAGEPGERGLKGHRGFTGL 1138
Query: 192 PQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241
P GP+G + P V S K+G+ PG PG
Sbjct: 1139 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188
Score = 32.3 bits (72), Expect = 1.0
Identities = 112/487 (22%), Positives = 143/487 (29%), Gaps = 129/487 (26%)
Query: 14 LGPEG--GEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71
+GP+G G Q A P RGD KGE G P
Sbjct: 116 VGPKGPPGPQGPAGEQGPRGDRGD------------------KGEKGAPGPR-------- 149
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131
G++G PGTP P PP G P P G
Sbjct: 150 -----------GRDGEPGTP---------------GNPGPPGPP----GPPGPPGLGGNF 179
Query: 132 STDIWA--DLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQ 189
+ + D + G + G + Q GP+ P PGPA G+ FQ
Sbjct: 180 AAQMAGGFDEKAGGAQLGVM--------QGPMGPMGPRGP-PGPA------GAPGPQGFQ 224
Query: 190 VDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSF 249
+P +P G +G G + PG P KPGD G
Sbjct: 225 GNPGEPGEPGVSG------------------------PMGPRGPPGPPGKPGDD-GEAG- 258
Query: 250 HRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMVWGKRGVRPSCSGAA 308
+ +GP R P V G P L + G GV+
Sbjct: 259 --KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA-GAPGVKGESGSPG 315
Query: 309 VRG-PLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGVGLL 367
G P P G G + + GA GA GQ A PP P P G G
Sbjct: 316 ENGSPGPMGPRGLPGERGRTGPAGA-----AGARGNDGQPGPAGPPGPVG--PAGGPGFP 368
Query: 368 GK-----SVRPKEPKHSSPGKKPAGRK-TRESQAAAREDNDPNRDEVPRAQLPTQKPELI 421
G P + + P G T S A +P D +P A+ P +
Sbjct: 369 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 428
Query: 422 SLSVRRGEYSSGDPNIRAPQ-VLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
+ G P R P G + P + P G+ Q P P P Q
Sbjct: 429 G--------APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE-QGPKGEPGPAGPQ 479
Query: 481 QPPGAQG 487
PG G
Sbjct: 480 GAPGPAG 486
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 57.0 bits (136), Expect = 4e-08
Identities = 123/494 (24%), Positives = 165/494 (33%), Gaps = 106/494 (21%)
Query: 15 GPEG--GEQAGAHTASPGAPRGD-GHGRDLNFGGQR--SGKGKGKGESGFTDPESFSFES 69
GP+G GE+ + A P GD G + G R +G+ G G P
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP--- 512
Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129
G++GRPG P A G V G P P+GA
Sbjct: 513 -------------GEDGRPGPPGPQGARG----------------QPGVMGFPGPKGANG 543
Query: 130 KGSTDIWADLEVGPSWRGALSPSPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187
+ L P RG PG + + +AGP PGP GPA E E+G+
Sbjct: 544 EPGKAGEKGLPGAPGLRGL----PGKDGETGAAGP-----PGPAGPAGERGEQGAPGPSG 594
Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG--DTCG 245
FQ P P G G K G Q PG PG G
Sbjct: 595 FQGLPGPPGPPGEGG------------------------KPGDQGVPGEAGAPGLVGPRG 630
Query: 246 RRSFHRRESYLQVQGPLLISPPRRL--TPVVERP--AVGELDVPSLKKMQSMVWGKRGVR 301
R F QG + PR L TP + P A G P + G +G+
Sbjct: 631 ERGFPGERGSPGAQG---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP----GLQGMP 683
Query: 302 PSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL----ALRGAFPAWGQRLSAVPPDPA 356
A + GP RG +G K + +G L G A G++ PP PA
Sbjct: 684 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 743
Query: 357 SFPPVSGV-GLLGKSVRPKEPKHSSP--GKKPAGRKTRESQAAAREDNDPNRDEVPRAQL 413
G G G++ P + P G K + +A + D + P
Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 803
Query: 414 PTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHP 473
Q P ++ + + G P T P A R+ P S+G+ PP P
Sbjct: 804 GPQGPTGVT-GPKGARGAQGPPG-------ATGFPGA--AGRVGP--PGSNGNPGPP-GP 850
Query: 474 PRPERQQQPPGAQG 487
P P + P GA+G
Sbjct: 851 PGPSGKDGPKGARG 864
Score = 37.4 bits (85), Expect = 0.032
Identities = 121/493 (24%), Positives = 156/493 (31%), Gaps = 86/493 (17%)
Query: 15 GPEG-----GEQAGAHTASPGAPRGD-GHGRDLNFGGQRSGKGKGKGESGFTDPESFSFE 68
GP G GE+ A A P RGD G G+ G+G G G P + E
Sbjct: 675 GPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIGPPGPAGANGE 733
Query: 69 SESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGAT 128
+ E+ G G G PG + G PA P G P +G
Sbjct: 734 -KGEVGPPGPAGSAGARGAPGERGETGPPG----------PAGFAGPPGADGQPGAKGEQ 782
Query: 129 AKGST--DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVP-----GPGPAWENPERG 181
+ D A GPS GA P GP ++ P GP G
Sbjct: 783 GEAGQKGDAGAPGPQGPS--GAPGPQ---------GPTGVTGPKGARGAQGPPGATGFPG 831
Query: 182 SKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241
+ R+ P GP G + D P R +G PG +PG
Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG 891
Query: 242 DTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMVWGKRGV 300
D + +GP +V P GE P L S GK+G
Sbjct: 892 D----------DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-PSGEPGKQGA 940
Query: 301 RPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359
P SG RGP P G G + EG+P + PP
Sbjct: 941 -PGASGD--RGPPGPVGPPGLTGPAGEPGREGSPG--------------ADGPPGRDGAA 983
Query: 360 PVSG----VGLLGKSVRPKEPKHSSPGKK-PAGRKTRESQAAAREDNDPNRDEVPRAQLP 414
V G G +G P P SPG P G++ +A A+ P+ R
Sbjct: 984 GVKGDRGETGAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1041
Query: 415 TQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPP 474
Q P R + +G+P R G FT + +P SGD Q P
Sbjct: 1042 PQGP-------RGDKGEAGEPGER-----GLKGHRGFTGLQGLPGPPGPSGD-QGASGPA 1088
Query: 475 RPERQQQPPGAQG 487
P + PPG G
Sbjct: 1089 GPSGPRGPPGPVG 1101
Score = 35.4 bits (80), Expect = 0.12
Identities = 67/271 (24%), Positives = 87/271 (32%), Gaps = 26/271 (9%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70
R GP G G P +G+ G SGK KG G + P + E
Sbjct: 818 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP-SGKDGPKGARGDSGPPGRAGEPG 876
Query: 71 SELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSS-----VQGHPSPE 125
QG G++G PG A G LA + + P G P P
Sbjct: 877 L----QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932
Query: 126 GATAK-----GSTDIWADLEVGPSWRGALSPSPG-EWQQASAGPLHLSVPG-PGPAWENP 178
G K S D VGP + PG E + GP PG G A
Sbjct: 933 GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PGRDGAAGVKG 987
Query: 179 ERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPK 238
+RG + P P + GPAG D + + P+ + G Q G
Sbjct: 988 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047
Query: 239 KPGDT--CGRRSFHRRESYLQVQGPLLISPP 267
G+ G R + +QG L PP
Sbjct: 1048 DKGEAGEPGERGLKGHRGFTGLQG--LPGPP 1076
Score = 35.0 bits (79), Expect = 0.16
Identities = 46/170 (27%), Positives = 58/170 (34%), Gaps = 24/170 (14%)
Query: 83 GQEGRPGTPVDDQAGGGDYSFYLADE---------PATIMPPSSVQGHPSPEGATAKGST 133
G+ GR G+P D G D + + + P PP G P P G T K
Sbjct: 963 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPP----GSPGPAGPTGKQGD 1018
Query: 134 --DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVD 191
+ A +GPS P+ Q GP G A E ERG K F
Sbjct: 1019 RGEAGAQGPMGPS-----GPAGARGIQGPQGPRG----DKGEAGEPGERGLKGHRGFTGL 1069
Query: 192 PQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241
P GP+G + P V S K+G+ PG PG
Sbjct: 1070 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119
Score = 32.3 bits (72), Expect = 1.0
Identities = 112/487 (22%), Positives = 143/487 (29%), Gaps = 129/487 (26%)
Query: 14 LGPEG--GEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71
+GP+G G Q A P RGD KGE G P
Sbjct: 47 VGPKGPPGPQGPAGEQGPRGDRGD------------------KGEKGAPGPR-------- 80
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131
G++G PGTP P PP G P P G
Sbjct: 81 -----------GRDGEPGTP---------------GNPGPPGPP----GPPGPPGLGGNF 110
Query: 132 STDIWA--DLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQ 189
+ + D + G + G + Q GP+ P PGPA G+ FQ
Sbjct: 111 AAQMAGGFDEKAGGAQLGVM--------QGPMGPMGPRGP-PGPA------GAPGPQGFQ 155
Query: 190 VDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSF 249
+P +P G +G G + PG P KPGD G
Sbjct: 156 GNPGEPGEPGVSG------------------------PMGPRGPPGPPGKPGDD-GEAG- 189
Query: 250 HRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMVWGKRGVRPSCSGAA 308
+ +GP R P V G P L + G GV+
Sbjct: 190 --KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA-GAPGVKGESGSPG 246
Query: 309 VRG-PLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGVGLL 367
G P P G G + + GA GA GQ A PP P P G G
Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGA-----AGARGNDGQPGPAGPPGPVG--PAGGPGFP 299
Query: 368 GK-----SVRPKEPKHSSPGKKPAGRK-TRESQAAAREDNDPNRDEVPRAQLPTQKPELI 421
G P + + P G T S A +P D +P A+ P +
Sbjct: 300 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 359
Query: 422 SLSVRRGEYSSGDPNIRAPQ-VLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480
+ G P R P G + P + P G+ Q P P P Q
Sbjct: 360 G--------APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE-QGPKGEPGPAGPQ 410
Query: 481 QPPGAQG 487
PG G
Sbjct: 411 GAPGPAG 417
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 55.1 bits (131), Expect = 1e-07
Identities = 115/447 (25%), Positives = 150/447 (33%), Gaps = 48/447 (10%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPES-FSFES---- 69
GP G +PG GDG G KG +G GF P +
Sbjct: 1159 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD-EGARGFPGPPGPIGLQGLPGP 1217
Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129
E E G V G G PG P Q G AD P PP SV S G
Sbjct: 1218 PGEKGENGDVGPMGPPGPPG-PRGPQGPNG------ADGPQG--PPGSVG---SVGGVGE 1265
Query: 130 KGSTDIWADLEVG----PSWRGALSPSPGEWQQASAGPLHLSVP--GPGPAWENPERGSK 183
KG E G P G P ++ AGP + P GP ++ +G+
Sbjct: 1266 KGEPG-----EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1320
Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT 243
+ F DP P GPAG D D+ D + G PG P K G
Sbjct: 1321 GPVGFPGDPGPPGEPGPAG---QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1377
Query: 244 CGRRSFHRRESYLQVQGPL-LISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302
G R+ +G PP + PV + G+ L+ + V G++G+
Sbjct: 1378 -GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV-GEQGLPG 1435
Query: 303 SCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAVPPDPASFPP 360
+ GP+ P G G K K +G P L L G G++ P P
Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1495
Query: 361 VSGVGLLGKSVRPKEPKHSSPG----KKPAGRKTRESQAAAREDN---DPNRDEVPRAQL 413
G G + P P PG + P G K A + D+ P P ++
Sbjct: 1496 AKGDGGIPGPAGPLGPP-GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554
Query: 414 PTQKPELISLSVRR---GEYSSGDPNI 437
P L S RR G + D NI
Sbjct: 1555 IQPLPILSSKKTRRHTEGMQADADDNI 1581
Score = 38.9 bits (89), Expect = 0.011
Identities = 53/208 (25%), Positives = 75/208 (36%), Gaps = 30/208 (14%)
Query: 15 GPEGGEQAGAHTASPGA---PRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71
GP G + T PG P DG G G+ KG+ GF +
Sbjct: 574 GPRGVQGPPGPTGKPGKRGRPGADG-------GRGMPGEPGAKGDRGFDGLPGLPGD--- 623
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131
+G G +G PG P DD G D P + + +G P G
Sbjct: 624 ----KGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGPRGLLGPRGTPGAP 675
Query: 132 STDIWADLEVGPSWRGALSP--SPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187
A ++ P +G + P PG QQ + GP L PGP GP E+G + +
Sbjct: 676 GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGEKGPQGKPG 733
Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESS 215
P A+GP G + S ++ +
Sbjct: 734 L---AGLPGADGPPGHPGKEGQSGEKGA 758
Score = 34.3 bits (77), Expect = 0.27
Identities = 129/533 (24%), Positives = 177/533 (33%), Gaps = 95/533 (17%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70
+ LGP G + + G DG G + KG+ KGE GF + +
Sbjct: 756 KGALGPPGPQGPIGYPGPRGVKGADG------VRGLKGSKGE-KGEDGFPGFKG-DMGLK 807
Query: 71 SELIEQGRVVLWGQEGRPGT-----PVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPE 125
+ E G++ G++G G P D G A E + P + G+P +
Sbjct: 808 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ-----AGEKGKLGVPG-LPGYPGRQ 861
Query: 126 GATAKGSTDI----WADLEVG-------PSWRGALSPSPGEWQQASAGPLHLSVPG---- 170
G KGST A+ E G P RG P+ + + GP P
Sbjct: 862 GP--KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 919
Query: 171 ----PGPAWENPERGSKSRLSF---QVDPQQPSAEGPAGLNTDDSDSADESSDLP----- 218
PGP E +G + + F + P P +G G ++ + P
Sbjct: 920 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 979
Query: 219 VIRVIISTKE----GSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVV 274
V+ T E G + PG P PG+ G +E GP IS + P
Sbjct: 980 VVGPQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKGDPGPQGISG--KDGPAG 1036
Query: 275 ERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRG---TLGRKVAQEKKSLEG 331
R GE +P + + K G P V P RG T G + +G
Sbjct: 1037 LRGFPGERGLPGAQGAPGL---KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1093
Query: 332 APELALRGAFPAWGQRLSAVPPDPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKT 390
P A G A G++ P PA V G VGL G P P S G
Sbjct: 1094 PPGPA--GEKGAPGEK---GPQGPAGRDGVQGPVGLPG----PAGPAGSPGEDGDKGEIG 1144
Query: 391 RESQAAAREDNDPNRDEVPRA-QLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQ-- 447
Q ++ D N P Q P P + G+P R Q + +
Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG--------GDGEPGPRGQQGMFGQKGD 1196
Query: 448 ---------PSAFTLRRLV--PRCHASSGDWQP--PVHPPRPERQQQPPGAQG 487
P L+ L P +GD P P PP P Q P GA G
Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1249
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 55.1 bits (131), Expect = 1e-07
Identities = 115/447 (25%), Positives = 150/447 (33%), Gaps = 48/447 (10%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPES-FSFES---- 69
GP G +PG GDG G KG +G GF P +
Sbjct: 1108 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD-EGARGFPGPPGPIGLQGLPGP 1166
Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129
E E G V G G PG P Q G AD P PP SV S G
Sbjct: 1167 PGEKGENGDVGPMGPPGPPG-PRGPQGPNG------ADGPQG--PPGSVG---SVGGVGE 1214
Query: 130 KGSTDIWADLEVG----PSWRGALSPSPGEWQQASAGPLHLSVP--GPGPAWENPERGSK 183
KG E G P G P ++ AGP + P GP ++ +G+
Sbjct: 1215 KGEPG-----EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1269
Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT 243
+ F DP P GPAG D D+ D + G PG P K G
Sbjct: 1270 GPVGFPGDPGPPGEPGPAG---QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1326
Query: 244 CGRRSFHRRESYLQVQGPL-LISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302
G R+ +G PP + PV + G+ L+ + V G++G+
Sbjct: 1327 -GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV-GEQGLPG 1384
Query: 303 SCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAVPPDPASFPP 360
+ GP+ P G G K K +G P L L G G++ P P
Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444
Query: 361 VSGVGLLGKSVRPKEPKHSSPG----KKPAGRKTRESQAAAREDN---DPNRDEVPRAQL 413
G G + P P PG + P G K A + D+ P P ++
Sbjct: 1445 AKGDGGIPGPAGPLGPP-GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503
Query: 414 PTQKPELISLSVRR---GEYSSGDPNI 437
P L S RR G + D NI
Sbjct: 1504 IQPLPILSSKKTRRHTEGMQADADDNI 1530
Score = 38.9 bits (89), Expect = 0.011
Identities = 53/208 (25%), Positives = 75/208 (36%), Gaps = 30/208 (14%)
Query: 15 GPEGGEQAGAHTASPGA---PRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71
GP G + T PG P DG G G+ KG+ GF +
Sbjct: 523 GPRGVQGPPGPTGKPGKRGRPGADG-------GRGMPGEPGAKGDRGFDGLPGLPGD--- 572
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131
+G G +G PG P DD G D P + + +G P G
Sbjct: 573 ----KGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGPRGLLGPRGTPGAP 624
Query: 132 STDIWADLEVGPSWRGALSP--SPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187
A ++ P +G + P PG QQ + GP L PGP GP E+G + +
Sbjct: 625 GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGEKGPQGKPG 682
Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESS 215
P A+GP G + S ++ +
Sbjct: 683 L---AGLPGADGPPGHPGKEGQSGEKGA 707
Score = 34.3 bits (77), Expect = 0.27
Identities = 129/533 (24%), Positives = 177/533 (33%), Gaps = 95/533 (17%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70
+ LGP G + + G DG G + KG+ KGE GF + +
Sbjct: 705 KGALGPPGPQGPIGYPGPRGVKGADG------VRGLKGSKGE-KGEDGFPGFKG-DMGLK 756
Query: 71 SELIEQGRVVLWGQEGRPGT-----PVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPE 125
+ E G++ G++G G P D G A E + P + G+P +
Sbjct: 757 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ-----AGEKGKLGVPG-LPGYPGRQ 810
Query: 126 GATAKGSTDI----WADLEVG-------PSWRGALSPSPGEWQQASAGPLHLSVPG---- 170
G KGST A+ E G P RG P+ + + GP P
Sbjct: 811 GP--KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 868
Query: 171 ----PGPAWENPERGSKSRLSF---QVDPQQPSAEGPAGLNTDDSDSADESSDLP----- 218
PGP E +G + + F + P P +G G ++ + P
Sbjct: 869 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 928
Query: 219 VIRVIISTKE----GSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVV 274
V+ T E G + PG P PG+ G +E GP IS + P
Sbjct: 929 VVGPQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKGDPGPQGISG--KDGPAG 985
Query: 275 ERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRG---TLGRKVAQEKKSLEG 331
R GE +P + + K G P V P RG T G + +G
Sbjct: 986 LRGFPGERGLPGAQGAPGL---KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1042
Query: 332 APELALRGAFPAWGQRLSAVPPDPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKT 390
P A G A G++ P PA V G VGL G P P S G
Sbjct: 1043 PPGPA--GEKGAPGEK---GPQGPAGRDGVQGPVGLPG----PAGPAGSPGEDGDKGEIG 1093
Query: 391 RESQAAAREDNDPNRDEVPRA-QLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQ-- 447
Q ++ D N P Q P P + G+P R Q + +
Sbjct: 1094 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG--------GDGEPGPRGQQGMFGQKGD 1145
Query: 448 ---------PSAFTLRRLV--PRCHASSGDWQP--PVHPPRPERQQQPPGAQG 487
P L+ L P +GD P P PP P Q P GA G
Sbjct: 1146 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1198
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 55.1 bits (131), Expect = 1e-07
Identities = 115/447 (25%), Positives = 150/447 (33%), Gaps = 48/447 (10%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPES-FSFES---- 69
GP G +PG GDG G KG +G GF P +
Sbjct: 1147 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD-EGARGFPGPPGPIGLQGLPGP 1205
Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129
E E G V G G PG P Q G AD P PP SV S G
Sbjct: 1206 PGEKGENGDVGPMGPPGPPG-PRGPQGPNG------ADGPQG--PPGSVG---SVGGVGE 1253
Query: 130 KGSTDIWADLEVG----PSWRGALSPSPGEWQQASAGPLHLSVP--GPGPAWENPERGSK 183
KG E G P G P ++ AGP + P GP ++ +G+
Sbjct: 1254 KGEPG-----EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1308
Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT 243
+ F DP P GPAG D D+ D + G PG P K G
Sbjct: 1309 GPVGFPGDPGPPGEPGPAG---QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1365
Query: 244 CGRRSFHRRESYLQVQGPL-LISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302
G R+ +G PP + PV + G+ L+ + V G++G+
Sbjct: 1366 -GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV-GEQGLPG 1423
Query: 303 SCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAVPPDPASFPP 360
+ GP+ P G G K K +G P L L G G++ P P
Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483
Query: 361 VSGVGLLGKSVRPKEPKHSSPG----KKPAGRKTRESQAAAREDN---DPNRDEVPRAQL 413
G G + P P PG + P G K A + D+ P P ++
Sbjct: 1484 AKGDGGIPGPAGPLGPP-GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542
Query: 414 PTQKPELISLSVRR---GEYSSGDPNI 437
P L S RR G + D NI
Sbjct: 1543 IQPLPILSSKKTRRHTEGMQADADDNI 1569
Score = 38.9 bits (89), Expect = 0.011
Identities = 53/208 (25%), Positives = 75/208 (36%), Gaps = 30/208 (14%)
Query: 15 GPEGGEQAGAHTASPGA---PRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71
GP G + T PG P DG G G+ KG+ GF +
Sbjct: 562 GPRGVQGPPGPTGKPGKRGRPGADG-------GRGMPGEPGAKGDRGFDGLPGLPGD--- 611
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131
+G G +G PG P DD G D P + + +G P G
Sbjct: 612 ----KGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGPRGLLGPRGTPGAP 663
Query: 132 STDIWADLEVGPSWRGALSP--SPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187
A ++ P +G + P PG QQ + GP L PGP GP E+G + +
Sbjct: 664 GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGEKGPQGKPG 721
Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESS 215
P A+GP G + S ++ +
Sbjct: 722 L---AGLPGADGPPGHPGKEGQSGEKGA 746
Score = 34.3 bits (77), Expect = 0.27
Identities = 129/533 (24%), Positives = 177/533 (33%), Gaps = 95/533 (17%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70
+ LGP G + + G DG G + KG+ KGE GF + +
Sbjct: 744 KGALGPPGPQGPIGYPGPRGVKGADG------VRGLKGSKGE-KGEDGFPGFKG-DMGLK 795
Query: 71 SELIEQGRVVLWGQEGRPGT-----PVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPE 125
+ E G++ G++G G P D G A E + P + G+P +
Sbjct: 796 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ-----AGEKGKLGVPG-LPGYPGRQ 849
Query: 126 GATAKGSTDI----WADLEVG-------PSWRGALSPSPGEWQQASAGPLHLSVPG---- 170
G KGST A+ E G P RG P+ + + GP P
Sbjct: 850 GP--KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 907
Query: 171 ----PGPAWENPERGSKSRLSF---QVDPQQPSAEGPAGLNTDDSDSADESSDLP----- 218
PGP E +G + + F + P P +G G ++ + P
Sbjct: 908 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 967
Query: 219 VIRVIISTKE----GSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVV 274
V+ T E G + PG P PG+ G +E GP IS + P
Sbjct: 968 VVGPQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKGDPGPQGISG--KDGPAG 1024
Query: 275 ERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRG---TLGRKVAQEKKSLEG 331
R GE +P + + K G P V P RG T G + +G
Sbjct: 1025 LRGFPGERGLPGAQGAPGL---KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1081
Query: 332 APELALRGAFPAWGQRLSAVPPDPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKT 390
P A G A G++ P PA V G VGL G P P S G
Sbjct: 1082 PPGPA--GEKGAPGEK---GPQGPAGRDGVQGPVGLPG----PAGPAGSPGEDGDKGEIG 1132
Query: 391 RESQAAAREDNDPNRDEVPRA-QLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQ-- 447
Q ++ D N P Q P P + G+P R Q + +
Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG--------GDGEPGPRGQQGMFGQKGD 1184
Query: 448 ---------PSAFTLRRLV--PRCHASSGDWQP--PVHPPRPERQQQPPGAQG 487
P L+ L P +GD P P PP P Q P GA G
Sbjct: 1185 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1237
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 54.7 bits (130), Expect = 2e-07
Identities = 104/425 (24%), Positives = 149/425 (35%), Gaps = 58/425 (13%)
Query: 15 GPEG--GEQAGAHTASPGAPRG----DGHGRDLNFGGQRSGKGKGKGESGFTDP------ 62
GP G G Q P P G DG ++ GQ+ KG KGE G P
Sbjct: 1129 GPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGD-KGEQGPPGPTGPQGP 1187
Query: 63 --ESFSFESESELIEQGRVVLWGQEGRPGT-----------------PVDDQAGGGDYSF 103
+ ++ E +G+ L+GQ+G G P ++ GD
Sbjct: 1188 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247
Query: 104 YLADEPATIMPPSSVQGHPSPEGATAKGSTDIWADLEVG----------PSWRGALSPSP 153
P PS G P+G G + A E G P G P
Sbjct: 1248 MGPPGPPGPRGPSGAPGADGPQGPPG-GIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306
Query: 154 GEWQQASAGPLHLS-VPGP-GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSA 211
++ +GP + PGP GP ++ +GS + F DP P GPAG + D
Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366
Query: 212 DESSDLPVIRVIISTKEGSQAKPG--SPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRR 269
D+ + + G PG P P GR+ + ++G PP +
Sbjct: 1367 DDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEG-----PPGK 1421
Query: 270 LTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPL-PRGTLGRKVAQEKKS 328
P+ + A G+ L+ + V G++G+ S GP+ P G G K K
Sbjct: 1422 TGPIGPQGAPGKPGPDGLRGIPGPV-GEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKG 1480
Query: 329 LEGAPEL-ALRGAFPAWGQRLSAVPPDP-ASFPPVSGVGLLGKS--VRPKEPKHSSPGKK 384
+G P L L G G++ P P S P G+ G S + P P
Sbjct: 1481 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPG 1540
Query: 385 PAGRK 389
P G K
Sbjct: 1541 PKGAK 1545
Score = 45.4 bits (106), Expect = 1e-04
Identities = 123/510 (24%), Positives = 169/510 (33%), Gaps = 135/510 (26%)
Query: 53 GKGESGFTDPESFSFESESE-LIEQGRVVL------WGQEGRPGTPVDDQAGGGDYSFYL 105
G G++G P + ES+++ +++Q R+ L G GRPG PV GG L
Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPG-PVGPPGSGG-----L 581
Query: 106 ADEPATIMP--PSSVQGHPSPEGATAK---GSTDIWADL--EVGPSW-RG--ALSPSPGE 155
EP + P P VQG P P G + +D + + GP RG L+ PGE
Sbjct: 582 KGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGE 641
Query: 156 -WQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQPSA------EGPAGLNTDDS 208
+ GP S P PGP ++ ERG + + P +P +GP G
Sbjct: 642 KGHRGDPGP---SGP-PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG 697
Query: 209 DSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPR 268
+ + P V G Q +PG P + G+ QG L P
Sbjct: 698 VTGMDGQPGPKGNV------GPQGEPGPPGQQGNP-------------GAQG--LPGPQG 736
Query: 269 RLTPVVERPAVGELDVPSLKKMQSMVW--GKRGVRPSCSGAAVRGPL-------PRGTLG 319
+ P E+ +G+ +P + GK G G GP PRG G
Sbjct: 737 AIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKG 796
Query: 320 R------KVAQEKKSLEGAPELALRGAFPAWGQRLSAVPP-------------------D 354
K + +K +G P +G G R PP D
Sbjct: 797 ADGIRGLKGTKGEKGEDGFP--GFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854
Query: 355 PASFPPVSGVGLLGKSVRPKEPKHSSP-------------GKKPAGRKT--RESQAAARE 399
P P G LG P P P G+K GR T + R
Sbjct: 855 PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEK-GGRGTPGKPGPRGQRG 913
Query: 400 DNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPR 459
P + PR P+ S G+ +G P R P G P+ F
Sbjct: 914 PTGPRGERGPRGITGKPGPKGNS----GGDGPAGPPGERGPN--GPQGPTGF-------- 959
Query: 460 CHASSGDWQPPVHPPRPERQQQPPGAQGCP 489
P P+ PPG G P
Sbjct: 960 --------------PGPKGPPGPPGKDGLP 975
Score = 42.0 bits (97), Expect = 0.001
Identities = 62/204 (30%), Positives = 75/204 (36%), Gaps = 27/204 (13%)
Query: 15 GPEGGEQAGAHTASPG-----APRG-DGHGRDLNFGGQR--SGKGKGKGESGFTDPESF- 65
GP G +G PG PRG G G+R +G +G G T P+
Sbjct: 571 GPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDR 630
Query: 66 SFESESELI-EQGRVVLWGQEGRPGTPVDDQAGGGDYSFY---LADEPAT--IMPPSSVQ 119
F+ + L E+G G G PG P DD G D L EP ++ P
Sbjct: 631 GFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPP 690
Query: 120 GHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGE-WQQASAGPLHLSVPGPGPAWENP 178
G P P G T D + GP PG QQ + G L PGP A P
Sbjct: 691 GPPGPPGVTGM-------DGQPGPKGNVGPQGEPGPPGQQGNPGAQGL--PGPQGAIGPP 741
Query: 179 ERGSKSRLSFQVDPQQPSAEGPAG 202
G K L P P A+GP G
Sbjct: 742 --GEKGPLGKPGLPGMPGADGPPG 763
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 53.9 bits (128), Expect = 3e-07
Identities = 131/526 (24%), Positives = 172/526 (32%), Gaps = 91/526 (17%)
Query: 14 LGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGK--GESGFTDPESFSFESES 71
+GP G A PGA GH G R G G G P
Sbjct: 1027 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG------- 1079
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQ--GHPSPEGATA 129
E+G G G PG P G + AD P PP V G P +G
Sbjct: 1080 ---EKGETGDVGPMGPPGPPGPRGPAGPNG----ADGPQG--PPGGVGNLGPPGEKGEPG 1130
Query: 130 K-GSTDIWADLEV-GPSWRGALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRL 186
+ GS I + V GP RG Q GP PGP GP ++ +G+ +
Sbjct: 1131 ESGSPGIQGEPGVKGP--RGERGEKGESGQPGEPGP-----PGPKGPTGDDGPKGNPGPV 1183
Query: 187 SFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT--- 243
F DP P GP G D D D G +PGSP G+
Sbjct: 1184 GFPGDPGPPGEGGPRG---QDGAKGDRGED------------GEPGQPGSPGPTGENGPP 1228
Query: 244 --------CGRRSFHRRESYLQVQG-PLLISPPRRLTPVVERPAVGELDVPSLKKMQSMV 294
G R+ +G P I P + PV G+ L+ + V
Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288
Query: 295 WGKRGVRPSCSG-AAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAV 351
G++G RP +G A GP+ P G G + K +G P L L G G++
Sbjct: 1289 -GQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1346
Query: 352 PPDPASFPPVSG-VGLLGKS-----------VRPKEPKHSSPGKKPAGRKTRESQAAARE 399
P P P G +G+ G S P PK + P G K +
Sbjct: 1347 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1406
Query: 400 DNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGD---PNIRAPQVLGTSQP---SAFTL 453
P + + LP Q P+ SV D P AP G + S +L
Sbjct: 1407 HPGPPGEVI--QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSL 1464
Query: 454 RRLVPRCHASSGDWQPPV---------HPPRPERQQQPPGAQGCPR 490
R + + +G P HP P+ + QGC R
Sbjct: 1465 REEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCAR 1510
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/229 (27%), Positives = 77/229 (33%), Gaps = 35/229 (15%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74
GP G PG+P G DL G R G G T P +
Sbjct: 404 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR-------GPQGLTGPPG-------KAG 449
Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGSTD 134
+GR G G PG P G D L E + QG P P G + D
Sbjct: 450 RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDD 508
Query: 135 IWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQ 194
E+GP RG S GP + P PG + +G K L Q +P
Sbjct: 509 G----EIGP--RGLPGESGPRGLLGPKGPPGIPGP-PGVRGMDGPQGPKGSLGPQGEPGP 561
Query: 195 PSAEGPAGLNTDDSDSADESSDLPVIRVIIST--KEGSQAKPGSPKKPG 241
P +G G + LP + I ++G Q KPG P PG
Sbjct: 562 PGQQGTPG-----------TQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599
Score = 41.6 bits (96), Expect = 0.002
Identities = 102/402 (25%), Positives = 129/402 (32%), Gaps = 72/402 (17%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESESE 72
GPEG + T PG P G L G G+ KG GF S E +
Sbjct: 683 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742
Query: 73 LI--------EQGRVVLWGQEGRPGTPVDDQA---GGGDYSFYLADEPATIMPPSSVQGH 121
+ E+G GQ G G A GGD E + P G
Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG-LPGPQGPNGF 801
Query: 122 PSPEGATAKGSTDIWADLEVGPSWRGALS-------PSPG-----EWQQASAGPL-HLSV 168
P P+G D L P RG + P P + GP+
Sbjct: 802 PGPKGPPGPPGKD---GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858
Query: 169 PGP-GPAWENPERGSKSRLSFQVDPQQPSA---EGPAGLNTDDSD-SADESSDLPVIRVI 223
PGP GP E G+ + + DP P A +GPAGL + ++ P ++
Sbjct: 859 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK-- 916
Query: 224 ISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELD 283
EG PG PG+ S GP I PP R P A GE
Sbjct: 917 --GNEGPSGPPGPAGSPGERGAAGS----------GGP--IGPPGRPGPQGPPGAAGEKG 962
Query: 284 VPSLKKMQSMVWGKRGVRPSCSGAAVRGPL----PRGTLGRKVAQEKKSLEGAPELALRG 339
VP G++G V+GP+ P G G K G P G
Sbjct: 963 VP----------GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP-----G 1007
Query: 340 AFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKHSSP 381
G + PP P P+ VG G + EP P
Sbjct: 1008 QKGTKGNKGEHGPPGPPG--PIGPVGQPGAAGADGEPGARGP 1047
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 53.9 bits (128), Expect = 3e-07
Identities = 131/526 (24%), Positives = 172/526 (32%), Gaps = 91/526 (17%)
Query: 14 LGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGK--GESGFTDPESFSFESES 71
+GP G A PGA GH G R G G G P
Sbjct: 1006 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG------- 1058
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQ--GHPSPEGATA 129
E+G G G PG P G + AD P PP V G P +G
Sbjct: 1059 ---EKGETGDVGPMGPPGPPGPRGPAGPNG----ADGPQG--PPGGVGNLGPPGEKGEPG 1109
Query: 130 K-GSTDIWADLEV-GPSWRGALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRL 186
+ GS I + V GP RG Q GP PGP GP ++ +G+ +
Sbjct: 1110 ESGSPGIQGEPGVKGP--RGERGEKGESGQPGEPGP-----PGPKGPTGDDGPKGNPGPV 1162
Query: 187 SFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT--- 243
F DP P GP G D D D G +PGSP G+
Sbjct: 1163 GFPGDPGPPGEGGPRG---QDGAKGDRGED------------GEPGQPGSPGPTGENGPP 1207
Query: 244 --------CGRRSFHRRESYLQVQG-PLLISPPRRLTPVVERPAVGELDVPSLKKMQSMV 294
G R+ +G P I P + PV G+ L+ + V
Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1267
Query: 295 WGKRGVRPSCSG-AAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAV 351
G++G RP +G A GP+ P G G + K +G P L L G G++
Sbjct: 1268 -GQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1325
Query: 352 PPDPASFPPVSG-VGLLGKS-----------VRPKEPKHSSPGKKPAGRKTRESQAAARE 399
P P P G +G+ G S P PK + P G K +
Sbjct: 1326 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1385
Query: 400 DNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGD---PNIRAPQVLGTSQP---SAFTL 453
P + + LP Q P+ SV D P AP G + S +L
Sbjct: 1386 HPGPPGEVI--QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSL 1443
Query: 454 RRLVPRCHASSGDWQPPV---------HPPRPERQQQPPGAQGCPR 490
R + + +G P HP P+ + QGC R
Sbjct: 1444 REEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCAR 1489
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/229 (27%), Positives = 77/229 (33%), Gaps = 35/229 (15%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74
GP G PG+P G DL G R G G T P +
Sbjct: 383 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR-------GPQGLTGPPG-------KAG 428
Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGSTD 134
+GR G G PG P G D L E + QG P P G + D
Sbjct: 429 RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDD 487
Query: 135 IWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQ 194
E+GP RG S GP + P PG + +G K L Q +P
Sbjct: 488 G----EIGP--RGLPGESGPRGLLGPKGPPGIPGP-PGVRGMDGPQGPKGSLGPQGEPGP 540
Query: 195 PSAEGPAGLNTDDSDSADESSDLPVIRVIIST--KEGSQAKPGSPKKPG 241
P +G G + LP + I ++G Q KPG P PG
Sbjct: 541 PGQQGTPG-----------TQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578
Score = 41.6 bits (96), Expect = 0.002
Identities = 102/402 (25%), Positives = 129/402 (32%), Gaps = 72/402 (17%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESESE 72
GPEG + T PG P G L G G+ KG GF S E +
Sbjct: 662 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 721
Query: 73 LI--------EQGRVVLWGQEGRPGTPVDDQA---GGGDYSFYLADEPATIMPPSSVQGH 121
+ E+G GQ G G A GGD E + P G
Sbjct: 722 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG-LPGPQGPNGF 780
Query: 122 PSPEGATAKGSTDIWADLEVGPSWRGALS-------PSPG-----EWQQASAGPL-HLSV 168
P P+G D L P RG + P P + GP+
Sbjct: 781 PGPKGPPGPPGKD---GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837
Query: 169 PGP-GPAWENPERGSKSRLSFQVDPQQPSA---EGPAGLNTDDSD-SADESSDLPVIRVI 223
PGP GP E G+ + + DP P A +GPAGL + ++ P ++
Sbjct: 838 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK-- 895
Query: 224 ISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELD 283
EG PG PG+ S GP I PP R P A GE
Sbjct: 896 --GNEGPSGPPGPAGSPGERGAAGS----------GGP--IGPPGRPGPQGPPGAAGEKG 941
Query: 284 VPSLKKMQSMVWGKRGVRPSCSGAAVRGPL----PRGTLGRKVAQEKKSLEGAPELALRG 339
VP G++G V+GP+ P G G K G P G
Sbjct: 942 VP----------GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP-----G 986
Query: 340 AFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKHSSP 381
G + PP P P+ VG G + EP P
Sbjct: 987 QKGTKGNKGEHGPPGPPG--PIGPVGQPGAAGADGEPGARGP 1026
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 53.9 bits (128), Expect = 3e-07
Identities = 131/526 (24%), Positives = 172/526 (32%), Gaps = 91/526 (17%)
Query: 14 LGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGK--GESGFTDPESFSFESES 71
+GP G A PGA GH G R G G G P
Sbjct: 1113 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG------- 1165
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQ--GHPSPEGATA 129
E+G G G PG P G + AD P PP V G P +G
Sbjct: 1166 ---EKGETGDVGPMGPPGPPGPRGPAGPNG----ADGPQG--PPGGVGNLGPPGEKGEPG 1216
Query: 130 K-GSTDIWADLEV-GPSWRGALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRL 186
+ GS I + V GP RG Q GP PGP GP ++ +G+ +
Sbjct: 1217 ESGSPGIQGEPGVKGP--RGERGEKGESGQPGEPGP-----PGPKGPTGDDGPKGNPGPV 1269
Query: 187 SFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT--- 243
F DP P GP G D D D G +PGSP G+
Sbjct: 1270 GFPGDPGPPGEGGPRG---QDGAKGDRGED------------GEPGQPGSPGPTGENGPP 1314
Query: 244 --------CGRRSFHRRESYLQVQG-PLLISPPRRLTPVVERPAVGELDVPSLKKMQSMV 294
G R+ +G P I P + PV G+ L+ + V
Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1374
Query: 295 WGKRGVRPSCSG-AAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAV 351
G++G RP +G A GP+ P G G + K +G P L L G G++
Sbjct: 1375 -GQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1432
Query: 352 PPDPASFPPVSG-VGLLGKS-----------VRPKEPKHSSPGKKPAGRKTRESQAAARE 399
P P P G +G+ G S P PK + P G K +
Sbjct: 1433 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1492
Query: 400 DNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGD---PNIRAPQVLGTSQP---SAFTL 453
P + + LP Q P+ SV D P AP G + S +L
Sbjct: 1493 HPGPPGEVI--QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSL 1550
Query: 454 RRLVPRCHASSGDWQPPV---------HPPRPERQQQPPGAQGCPR 490
R + + +G P HP P+ + QGC R
Sbjct: 1551 REEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCAR 1596
Score = 41.6 bits (96), Expect = 0.002
Identities = 62/229 (27%), Positives = 77/229 (33%), Gaps = 35/229 (15%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74
GP G PG+P G DL G R G G T P +
Sbjct: 490 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR-------GPQGLTGPPG-------KAG 535
Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGSTD 134
+GR G G PG P G D L E + QG P P G + D
Sbjct: 536 RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDD 594
Query: 135 IWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQ 194
E+GP RG S GP + P PG + +G K L Q +P
Sbjct: 595 G----EIGP--RGLPGESGPRGLLGPKGPPGIPGP-PGVRGMDGPQGPKGSLGPQGEPGP 647
Query: 195 PSAEGPAGLNTDDSDSADESSDLPVIRVIIST--KEGSQAKPGSPKKPG 241
P +G G + LP + I ++G Q KPG P PG
Sbjct: 648 PGQQGTPG-----------TQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 685
Score = 41.6 bits (96), Expect = 0.002
Identities = 102/402 (25%), Positives = 129/402 (32%), Gaps = 72/402 (17%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESESE 72
GPEG + T PG P G L G G+ KG GF S E +
Sbjct: 769 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 828
Query: 73 LI--------EQGRVVLWGQEGRPGTPVDDQA---GGGDYSFYLADEPATIMPPSSVQGH 121
+ E+G GQ G G A GGD E + P G
Sbjct: 829 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG-LPGPQGPNGF 887
Query: 122 PSPEGATAKGSTDIWADLEVGPSWRGALS-------PSPG-----EWQQASAGPL-HLSV 168
P P+G D L P RG + P P + GP+
Sbjct: 888 PGPKGPPGPPGKD---GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944
Query: 169 PGP-GPAWENPERGSKSRLSFQVDPQQPSA---EGPAGLNTDDSD-SADESSDLPVIRVI 223
PGP GP E G+ + + DP P A +GPAGL + ++ P ++
Sbjct: 945 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK-- 1002
Query: 224 ISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELD 283
EG PG PG+ S GP I PP R P A GE
Sbjct: 1003 --GNEGPSGPPGPAGSPGERGAAGS----------GGP--IGPPGRPGPQGPPGAAGEKG 1048
Query: 284 VPSLKKMQSMVWGKRGVRPSCSGAAVRGPL----PRGTLGRKVAQEKKSLEGAPELALRG 339
VP G++G V+GP+ P G G K G P G
Sbjct: 1049 VP----------GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP-----G 1093
Query: 340 AFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKHSSP 381
G + PP P P+ VG G + EP P
Sbjct: 1094 QKGTKGNKGEHGPPGPPG--PIGPVGQPGAAGADGEPGARGP 1133
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 48.5 bits (114), Expect = 1e-05
Identities = 97/420 (23%), Positives = 144/420 (34%), Gaps = 88/420 (20%)
Query: 12 AGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE- 70
+G P + A+T +G + G+ +S D S S E++
Sbjct: 153 SGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDV 212
Query: 71 ----SELIEQGRVVLWGQEGRPG---TPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPS 123
SE I Q R +G PG TP G S A +P SS + S
Sbjct: 213 EVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDS 272
Query: 124 PEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSK 183
E A + + + G+ Q A PA E+P +G+
Sbjct: 273 EEETPAAKAL--------------LQAKASGKTSQVGAAS--------APAKESPRKGAA 310
Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKKPGD 242
+ P A+ AG +DS S+ E SD S +E +QAKP S K P
Sbjct: 311 PAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKAPQV 359
Query: 243 TCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302
S +ES + P +PPR+ P + VG+ + S +
Sbjct: 360 RAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE---------- 404
Query: 303 SCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVS 362
R L A + K L +P++ PAS
Sbjct: 405 --------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS---TM 435
Query: 363 GVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+ L
Sbjct: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%)
Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171
+PP V G +P K D + E S G + + Q+ S G + + P
Sbjct: 447 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 505
Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231
PA P++ ++ QV ++P D+S+S++ESSD + +Q
Sbjct: 506 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 554
Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291
AKP C +++ ++P R T +
Sbjct: 555 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 594
Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350
P+ S AV G R ++E S E LA+ G + G+ L
Sbjct: 595 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 647
Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410
A+ PV G LG+ P P + P + +E ++ E++D
Sbjct: 648 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 701
Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470
AQ+ T SV++ + + RAP GT + S +PP
Sbjct: 702 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 753
Query: 471 VHPPR 475
V P+
Sbjct: 754 VRNPQ 758
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 48.5 bits (114), Expect = 1e-05
Identities = 97/420 (23%), Positives = 144/420 (34%), Gaps = 88/420 (20%)
Query: 12 AGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE- 70
+G P + A+T +G + G+ +S D S S E++
Sbjct: 153 SGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDV 212
Query: 71 ----SELIEQGRVVLWGQEGRPG---TPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPS 123
SE I Q R +G PG TP G S A +P SS + S
Sbjct: 213 EVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDS 272
Query: 124 PEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSK 183
E A + + + G+ Q A PA E+P +G+
Sbjct: 273 EEETPAAKAL--------------LQAKASGKTSQVGAAS--------APAKESPRKGAA 310
Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKKPGD 242
+ P A+ AG +DS S+ E SD S +E +QAKP S K P
Sbjct: 311 PAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKAPQV 359
Query: 243 TCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302
S +ES + P +PPR+ P + VG+ + S +
Sbjct: 360 RAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE---------- 404
Query: 303 SCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVS 362
R L A + K L +P++ PAS
Sbjct: 405 --------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS---TM 435
Query: 363 GVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+ L
Sbjct: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%)
Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171
+PP V G +P K D + E S G + + Q+ S G + + P
Sbjct: 447 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 505
Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231
PA P++ ++ QV ++P D+S+S++ESSD + +Q
Sbjct: 506 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 554
Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291
AKP C +++ ++P R T +
Sbjct: 555 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 594
Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350
P+ S AV G R ++E S E LA+ G + G+ L
Sbjct: 595 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 647
Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410
A+ PV G LG+ P P + P + +E ++ E++D
Sbjct: 648 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 701
Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470
AQ+ T SV++ + + RAP GT + S +PP
Sbjct: 702 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 753
Query: 471 VHPPR 475
V P+
Sbjct: 754 VRNPQ 758
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 48.1 bits (113), Expect = 2e-05
Identities = 121/503 (24%), Positives = 163/503 (32%), Gaps = 102/503 (20%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--------KGESGFT-DPESF 65
G +G A +PG P G GG KG KG++G +P
Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454
Query: 66 SFESE-SELIEQGRVVLWGQEGRPGTP--VDDQAGGGDYSFYLADEPATIMPPSSVQGHP 122
+ E+G+ G+ G G P ++ G G F AD A P+ +G P
Sbjct: 455 GVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSP 514
Query: 123 SPEGATAKGST-DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERG 181
P G KGS + E G L+ SPG S GP + P PGPA ++ G
Sbjct: 515 GPAGP--KGSPGEAGRPGEAGLPGAKGLTGSPG-----SPGPDGKTGP-PGPAGQDGRPG 566
Query: 182 SKSRLSFQVDPQQPSAEGPAGLN--TDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKK 239
P P A G AG+ +A E K G + PG P
Sbjct: 567 P---------PGPPGARGQAGVMGFPGPKGAAGEPG-----------KAGERGVPGPPGA 606
Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVW---- 295
G ++ QG PP P ER G P + +
Sbjct: 607 VGPA-------GKDGEAGAQG-----PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE 654
Query: 296 ----GKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAV 351
G++GV P GA P P G G + ++ ++G P PA + +
Sbjct: 655 AGKPGEQGV-PGDLGA----PGPSGARGERGFPGERGVQGPPG-------PAGPRGANGA 702
Query: 352 PPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKK-----PAGRKTRESQAAAREDNDPNRD 406
P + + G G P PG++ P + R D P +D
Sbjct: 703 PGNDGAKGDAGAPGAPGSQGAP--GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760
Query: 407 EVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGD 466
V P P +GE G S P+ T R P GD
Sbjct: 761 GVRGLTGPIGPPGPAGAPGDKGE-------------SGPSGPAGPTGARGAP------GD 801
Query: 467 WQPPVHPPRPERQQQPPGAQGCP 489
P PP P PPGA G P
Sbjct: 802 RGEP-GPPGPAGFAGPPGADGQP 823
Score = 47.0 bits (110), Expect = 4e-05
Identities = 94/373 (25%), Positives = 126/373 (33%), Gaps = 60/373 (16%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESESE 72
GP G + A + G P GH G + G KGE G + +
Sbjct: 245 GPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG----APGQ 300
Query: 73 LIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGAT-AKG 131
+ +G L G+ GRPG P A G D + A P P+ G P GA AKG
Sbjct: 301 MGPRG---LPGERGRPGAPGPAGARGNDGATGAAGPPG----PTGPAGPPGFPGAVGAKG 353
Query: 132 STDIWADLEVGPSW-RGALSPSPGEWQQASAGPLHLSVP--GPGPAWENPERGSKSRLSF 188
E GP RG+ P + GP + P PG + +G+
Sbjct: 354 --------EAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405
Query: 189 QVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRS 248
P P A GP+G +G+ +PG+P GDT +
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPG---------------PKGNSGEPGAPGSKGDTGAKGE 450
Query: 249 FHRRESYLQVQGPLLI-SPPRRLTPVVERPAVGELDVPSLKKMQSMVW--GKRGVRPSCS 305
GP+ + PP +R A GE L G RG +
Sbjct: 451 ----------PGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500
Query: 306 GAAVRGPL-PRGTLGRKVAQEKKSLEGAP-ELALRGAFPAWGQRLSAVPPDPASFPPVSG 363
A +GP RG+ G + G P E L GA G + PD + PP
Sbjct: 501 VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP-GSPGPDGKTGPP--- 556
Query: 364 VGLLGKSVRPKEP 376
G G+ RP P
Sbjct: 557 -GPAGQDGRPGPP 568
Score = 42.4 bits (98), Expect = 0.001
Identities = 117/476 (24%), Positives = 150/476 (31%), Gaps = 88/476 (18%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFE-- 68
R GP G G P G+ G +GK GKG G T P E
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGP-AGKEGGKGPRGETGPAGRPGEVG 923
Query: 69 ---SESELIEQGRVVLWGQEGRPGTP----VDDQAGGGDYSFYLADEPATIMP-PSSVQG 120
E+G G G PGTP + Q G + +P PS G
Sbjct: 924 PPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG 983
Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPG----PGPAWE 176
P GA+ + GP L+ PGE + A P PG PG +
Sbjct: 984 KQGPSGASGERGPP-------GPMGPPGLAGPPGESGREGA-PGAEGSPGRDGSPGAKGD 1035
Query: 177 NPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGS 236
E G P P GPAG + D ++ PV V G Q G
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095
Query: 237 PKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWG 296
+ G+ G R + +QGP PP +P + P
Sbjct: 1096 KGETGEQ-GDRGIKGHRGFSGLQGP--PGPPG--SPGEQGP------------------- 1131
Query: 297 KRGVRPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAP-ELALRGAFPAWGQRLSAVPPD 354
SGA+ GP PRG G A K L G P + G G PP
Sbjct: 1132 --------SGAS--GPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPG 1181
Query: 355 PASFPPVSGVGLLG--KSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQ 412
P P G G S P+ P+ + GR R A D D D ++
Sbjct: 1182 PPGPPGPPGPPSAGFDFSFLPQPPQEKA---HDGGRYYRADDANVVRDRDLEVDTTLKS- 1237
Query: 413 LPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQ 468
S NIR+P+ G+ + A T R L CH+ DW+
Sbjct: 1238 -----------------LSQQIENIRSPE--GSRKNPARTCRDL-KMCHS---DWK 1270
Score = 34.3 bits (77), Expect = 0.27
Identities = 94/384 (24%), Positives = 117/384 (30%), Gaps = 41/384 (10%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKG--KGKGESGFTDPESFSFE 68
R G G + A +PGAP G G+R G KG+ G P+
Sbjct: 697 RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS 756
Query: 69 SESELIE--QGRVVLWGQEGRPGT-----------PVDDQAGGGDYSFYLADEPATIMPP 115
+ + G + G G PG P + GD PA P
Sbjct: 757 PGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP 816
Query: 116 SSVQGHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAW 175
G P +G D A + GP + PG A + GP
Sbjct: 817 PGADGQPGAKGEPG----DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872
Query: 176 ENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPG 235
G+ R V P PS G AG + E P + + G PG
Sbjct: 873 ATGFPGAAGR----VGPPGPS--GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG 926
Query: 236 SPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMV 294
P G+ G GP I+ R VV P GE P L S
Sbjct: 927 PPGPAGEK-GSPGADGPAGAPGTPGPQGIAGQR---GVVGLPGQRGERGFPGLPG-PSGE 981
Query: 295 WGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAP----ELALRGAFPAWGQRLSA 350
GK+G PS + P P G G + EGAP G+ A G R
Sbjct: 982 PGKQG--PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039
Query: 351 VPPDPASFPPVSG----VGLLGKS 370
P P P G VG GKS
Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKS 1063
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 46.6 bits (109), Expect = 5e-05
Identities = 66/275 (24%), Positives = 101/275 (36%), Gaps = 31/275 (11%)
Query: 13 GLGPEGGEQ-AGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71
G G GG++ G H + G GDGHG GG+ SG GKG G +D + +S
Sbjct: 555 GHGSGGGQRPGGGHGSGGGQGPGDGHGSG---GGKNSGGGKGSGSGKGSDGDGERGKSLK 611
Query: 72 ELIEQGRVVLWGQEGRP-------------GTPVDDQAGGGDYSFYLADEPAT--IMPPS 116
+ G++ Q+ P GT ++GG ++ D AT
Sbjct: 612 KRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAK 671
Query: 117 SVQGHPSPEGATAKG-----STDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGP 171
V+ PEGA A+G + D D P G +P P ++S
Sbjct: 672 EVKDAEIPEGA-ARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKK 730
Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231
+ +P S+ + P A P D++ D+S D + G+
Sbjct: 731 RHS-RSPFEDSRGYMMMFPRVSPPPAPSPP--KAPDTNKEDDSKDNDSESDYMFMAPGAG 787
Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISP 266
A P +P+ P +S+ SY + P SP
Sbjct: 788 AIPKNPRNPQGGSSSKSW---SSYFSLPNPFRSSP 819
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 46.2 bits (108), Expect = 7e-05
Identities = 82/278 (29%), Positives = 96/278 (34%), Gaps = 58/278 (20%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70
R LGPEG E PGAP +G F G R G KGE G DP
Sbjct: 939 RGQLGPEGDE---GPMGPPGAPGLEGQPGRKGFPG-RPGLDGVKGEPG--DPGR-----P 987
Query: 71 SELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPS-PEGATA 129
+ EQG + G G PG V ++ G P + P GHP P G
Sbjct: 988 GPVGEQGFMGFIGLVGEPGI-VGEKGDRGMMG------PPGVPGPKGSMGHPGMPGGMGT 1040
Query: 130 KGSTDIWADLEVGPSWR-GALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187
G E GP G+ P + GP GP GPA E RG K
Sbjct: 1041 PG--------EPGPQGPPGSRGPPGMRGAKGRRGPR-----GPDGPAGEQGSRGLKGPPG 1087
Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRR 247
Q P +P +G AG E L GS+ PG P P G +
Sbjct: 1088 PQGRPGRPGQQGVAG----------ERGHL-----------GSRGFPGIP-GPSGPPGTK 1125
Query: 248 SFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVP 285
QGP I PP + P AVGE +P
Sbjct: 1126 GLPGEPGPQGPQGP--IGPPGEMGPKGPPGAVGEPGLP 1161
Score = 37.7 bits (86), Expect = 0.025
Identities = 118/503 (23%), Positives = 160/503 (31%), Gaps = 111/503 (22%)
Query: 11 RAGLGPEG--GEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFE 68
R GP+G GE+ P G + +SGK KG +G + +
Sbjct: 1206 RGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY--- 1262
Query: 69 SESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGAT 128
+ +L E G + G G PGTP + G + P+ G +G
Sbjct: 1263 -QGQLGEMG---VPGDPGPPGTPGPKGSRGS-------------LGPTGAPGRMGAQGEP 1305
Query: 129 AKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGP----GPAWENPERGSKS 184
D + VGP G P + +Q G PGP GP + +RG
Sbjct: 1306 GLAGYDGHKGI-VGPL--GPPGPKGEKGEQGEDGKAE-GPPGPPGDRGPVGDRGDRGEPG 1361
Query: 185 RLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTC 244
DP P EG GL K G Q +PG P
Sbjct: 1362 ------DPGYPGQEGVQGLR---------------------GKPGQQGQPGHP------- 1387
Query: 245 GRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSM--VWGKRGV-- 300
G R + + +GP + G+ P + +Q + + G RGV
Sbjct: 1388 GPRGWPGPKGSKGAEGP--------------KGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433
Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
R G A LP G G+ Q ++ +G P G G+R + P A P
Sbjct: 1434 RQGLEGIAGPDGLP-GRDGQAGQQGEQGDDGDP-----GPMGPAGKRGN---PGVAGLPG 1484
Query: 361 VSG-VGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPE 419
G G G+S P + PGK R T +P P P
Sbjct: 1485 AQGPPGFKGESGLPGQ--LGPPGK----RGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPG 1538
Query: 420 LISLSVRRGEYS----SGDPNIRAPQVLGTSQPSAFTLRRLVPR-------CHASSGDW- 467
+ L +G G R P L + L L P S GDW
Sbjct: 1539 MAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWG 1598
Query: 468 -QPPVHPPRPERQQQPPGAQGCP 489
Q P PP P + PPG G P
Sbjct: 1599 LQGPRGPPGPRGRPGPPGPPGGP 1621
Score = 37.7 bits (86), Expect = 0.025
Identities = 89/378 (23%), Positives = 131/378 (34%), Gaps = 83/378 (21%)
Query: 15 GPEG--GEQA--GAHTASPGAP--------RGD-GHGRDLNFGGQRSGKG-KGK----GE 56
GP+G GEQ G PG P RGD G D + GQ +G +GK G+
Sbjct: 1324 GPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQ 1383
Query: 57 SGFTDPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPS 116
G P + S+ E + G++G+ G P G
Sbjct: 1384 PGHPGPRGWPGPKGSKGAEGPK----GKQGKAGAPGRRGVQG------------------ 1421
Query: 117 SVQGHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWE 176
+QG P P G + + A + P G + GP+ GP
Sbjct: 1422 -LQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPM-----GPAGKRG 1475
Query: 177 NPE----RGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQA 232
NP G++ F+ + P GP G + + LP G+Q
Sbjct: 1476 NPGVAGLPGAQGPPGFKGESGLPGQLGPPGKR-----GTEGRTGLP----------GNQG 1520
Query: 233 KPGSPKKPGDTCGRRSFHRRESYLQVQGP------LLISPPRRLTPVVERPA-VGELDVP 285
+PGS +PGD+ G F +GP I PR ++ + VG L +
Sbjct: 1521 EPGSKGQPGDS-GEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGIL 1579
Query: 286 SLKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAP----ELALRGAF 341
S + G +G + S ++G PRG G + G P + L AF
Sbjct: 1580 G----PSGLPGPKGDKGSRGDWGLQG--PRGPPGPRGRPGPPGPPGGPIQLQQDDLGAAF 1633
Query: 342 PAWGQRLSAVPPDPASFP 359
W A+ P+ S+P
Sbjct: 1634 QTWMDTSGALRPESYSYP 1651
Score = 30.4 bits (67), Expect = 3.9
Identities = 124/528 (23%), Positives = 172/528 (32%), Gaps = 89/528 (16%)
Query: 15 GPEGGE-QAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESES 71
GP G + Q G SPG DG D+ G G KG G+ P E
Sbjct: 667 GPPGAKGQKGDPGLSPGKAH-DGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQ 725
Query: 72 ELIE--QGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129
E G G++G PG PV D G + + +G P G
Sbjct: 726 PGPEGSPGAKGYPGRQGLPG-PVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRG 784
Query: 130 KGSTDIWADL--EVGPSWRGALSPSPGEWQQASAGPLHLSVPGP-------------GPA 174
K + + E GP L +PGE L +PGP GP
Sbjct: 785 KMGMPGFPGVFGERGPP---GLDGNPGE----------LGLPGPPGVPGLIGDLGVLGPI 831
Query: 175 WENPERGSKSRLSFQVDPQ---QPSAEGPAGLNTDDSDSADESSDL------------PV 219
+G K + +P +G G++ D D+ S P+
Sbjct: 832 GYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPL 891
Query: 220 IRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPR-RLTPVVERPA 278
+V G PG PGD G + E G + PR +L P +
Sbjct: 892 GKVGDKGSIGFPGPPGPEGFPGDI-GPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGP 950
Query: 279 VGELDVPSLKKMQSMVWGKRGV--RPSCSGAAVRG----PLPRGTLGRKVAQEKKSLEGA 332
+G P L+ G++G RP G V+G P G +G + L G
Sbjct: 951 MGPPGAPGLEGQP----GRKGFPGRPGLDG--VKGEPGDPGRPGPVGEQGFMGFIGLVGE 1004
Query: 333 PELALRGAFPAWGQRLSAVPPD-PASFPPVSGVGLLGKSVRPKEPKHSSP--GKKPAGRK 389
P G G R PP P + G+ G P EP P + P G +
Sbjct: 1005 P-----GIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059
Query: 390 TRESQAAAREDNDPNRDE-------VPRAQLPTQKPELISLSVRRGEYSS-GDPNIRAPQ 441
+ + R + P ++ P Q +P ++ RG S G P I P
Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGP- 1118
Query: 442 VLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQQPPGAQGCP 489
S P + +P G Q P+ PP + PPGA G P
Sbjct: 1119 ----SGPPG---TKGLPGEPGPQGP-QGPIGPPGEMGPKGPPGAVGEP 1158
>gi|27262667 colony stimulating factor 1 isoform a precursor [Homo
sapiens]
Length = 554
Score = 45.4 bits (106), Expect = 1e-04
Identities = 72/300 (24%), Positives = 107/300 (35%), Gaps = 67/300 (22%)
Query: 167 SVPGPGPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIIST 226
++P PA +P + P PS AGL +DS+ + SS LP + + +
Sbjct: 196 AIPSSDPASVSPHQ-----------PLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTV 244
Query: 227 KEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPS 286
GS + + P TC +SF E+ + + SP RP+VG + P
Sbjct: 245 DPGSAKQ----RPPRSTC--QSFEPPETPVVKDSTIGGSPQ-------PRPSVGAFN-PG 290
Query: 287 LKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQ 346
++ + G V SG A P+P+GT + S G + A P+
Sbjct: 291 MEDILDSAMGTNWVPEEASGEASEIPVPQGT------ELSPSRPGGGSMQTEPARPS--N 342
Query: 347 RLSAVPPDPASFP---PVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDP 403
LSA P PAS P G V P P P +KT A R+ +P
Sbjct: 343 FLSASSPLPASAKGQQPADVTGTALPRVGPVRPTGQDWNHTP--QKTDHPSALLRDPPEP 400
Query: 404 NRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHAS 463
G P I + + G S PS + + + R H+S
Sbjct: 401 -----------------------------GSPRISSLRPQGLSNPSTLSAQPQLSRSHSS 431
>gi|27262661 colony stimulating factor 1 isoform a precursor [Homo
sapiens]
Length = 554
Score = 45.4 bits (106), Expect = 1e-04
Identities = 72/300 (24%), Positives = 107/300 (35%), Gaps = 67/300 (22%)
Query: 167 SVPGPGPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIIST 226
++P PA +P + P PS AGL +DS+ + SS LP + + +
Sbjct: 196 AIPSSDPASVSPHQ-----------PLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTV 244
Query: 227 KEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPS 286
GS + + P TC +SF E+ + + SP RP+VG + P
Sbjct: 245 DPGSAKQ----RPPRSTC--QSFEPPETPVVKDSTIGGSPQ-------PRPSVGAFN-PG 290
Query: 287 LKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQ 346
++ + G V SG A P+P+GT + S G + A P+
Sbjct: 291 MEDILDSAMGTNWVPEEASGEASEIPVPQGT------ELSPSRPGGGSMQTEPARPS--N 342
Query: 347 RLSAVPPDPASFP---PVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDP 403
LSA P PAS P G V P P P +KT A R+ +P
Sbjct: 343 FLSASSPLPASAKGQQPADVTGTALPRVGPVRPTGQDWNHTP--QKTDHPSALLRDPPEP 400
Query: 404 NRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHAS 463
G P I + + G S PS + + + R H+S
Sbjct: 401 -----------------------------GSPRISSLRPQGLSNPSTLSAQPQLSRSHSS 431
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 45.1 bits (105), Expect = 2e-04
Identities = 88/363 (24%), Positives = 123/363 (33%), Gaps = 67/363 (18%)
Query: 68 ESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGA 127
E ESE E+G +E GT +A A PA P P +
Sbjct: 267 EEESESSEEGSES--EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324
Query: 128 TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASA-------GPLHLSVPGPGPAWENPER 180
T E S S S E A A G PA E+P +
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKK 239
G+ + P A+ AG +DS S+ E SD S +E +QAKP S K
Sbjct: 385 GAAPAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKA 433
Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG 299
P S +ES + P +PPR+ P + VG+ + S +
Sbjct: 434 PQVRAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE------- 481
Query: 300 VRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359
R L A + K L +P++ PAS
Sbjct: 482 -----------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS-- 510
Query: 360 PVSGVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQK 417
G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+
Sbjct: 511 -TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE 569
Query: 418 PEL 420
L
Sbjct: 570 KSL 572
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%)
Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171
+PP V G +P K D + E S G + + Q+ S G + + P
Sbjct: 524 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231
PA P++ ++ QV ++P D+S+S++ESSD + +Q
Sbjct: 583 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 631
Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291
AKP C +++ ++P R T +
Sbjct: 632 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 671
Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350
P+ S AV G R ++E S E LA+ G + G+ L
Sbjct: 672 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724
Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410
A+ PV G LG+ P P + P + +E ++ E++D
Sbjct: 725 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470
AQ+ T SV++ + + RAP GT + S +PP
Sbjct: 779 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830
Query: 471 VHPPR 475
V P+
Sbjct: 831 VRNPQ 835
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 45.1 bits (105), Expect = 2e-04
Identities = 88/363 (24%), Positives = 123/363 (33%), Gaps = 67/363 (18%)
Query: 68 ESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGA 127
E ESE E+G +E GT +A A PA P P +
Sbjct: 267 EEESESSEEGSES--EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324
Query: 128 TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASA-------GPLHLSVPGPGPAWENPER 180
T E S S S E A A G PA E+P +
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKK 239
G+ + P A+ AG +DS S+ E SD S +E +QAKP S K
Sbjct: 385 GAAPAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKA 433
Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG 299
P S +ES + P +PPR+ P + VG+ + S +
Sbjct: 434 PQVRAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE------- 481
Query: 300 VRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359
R L A + K L +P++ PAS
Sbjct: 482 -----------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS-- 510
Query: 360 PVSGVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQK 417
G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+
Sbjct: 511 -TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE 569
Query: 418 PEL 420
L
Sbjct: 570 KSL 572
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%)
Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171
+PP V G +P K D + E S G + + Q+ S G + + P
Sbjct: 524 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231
PA P++ ++ QV ++P D+S+S++ESSD + +Q
Sbjct: 583 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 631
Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291
AKP C +++ ++P R T +
Sbjct: 632 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 671
Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350
P+ S AV G R ++E S E LA+ G + G+ L
Sbjct: 672 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724
Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410
A+ PV G LG+ P P + P + +E ++ E++D
Sbjct: 725 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470
AQ+ T SV++ + + RAP GT + S +PP
Sbjct: 779 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830
Query: 471 VHPPR 475
V P+
Sbjct: 831 VRNPQ 835
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 45.1 bits (105), Expect = 2e-04
Identities = 88/363 (24%), Positives = 123/363 (33%), Gaps = 67/363 (18%)
Query: 68 ESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGA 127
E ESE E+G +E GT +A A PA P P +
Sbjct: 267 EEESESSEEGSES--EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324
Query: 128 TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASA-------GPLHLSVPGPGPAWENPER 180
T E S S S E A A G PA E+P +
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKK 239
G+ + P A+ AG +DS S+ E SD S +E +QAKP S K
Sbjct: 385 GAAPAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKA 433
Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG 299
P S +ES + P +PPR+ P + VG+ + S +
Sbjct: 434 PQVRAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE------- 481
Query: 300 VRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359
R L A + K L +P++ PAS
Sbjct: 482 -----------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS-- 510
Query: 360 PVSGVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQK 417
G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+
Sbjct: 511 -TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE 569
Query: 418 PEL 420
L
Sbjct: 570 KSL 572
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%)
Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171
+PP V G +P K D + E S G + + Q+ S G + + P
Sbjct: 524 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231
PA P++ ++ QV ++P D+S+S++ESSD + +Q
Sbjct: 583 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 631
Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291
AKP C +++ ++P R T +
Sbjct: 632 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 671
Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350
P+ S AV G R ++E S E LA+ G + G+ L
Sbjct: 672 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724
Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410
A+ PV G LG+ P P + P + +E ++ E++D
Sbjct: 725 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470
AQ+ T SV++ + + RAP GT + S +PP
Sbjct: 779 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830
Query: 471 VHPPR 475
V P+
Sbjct: 831 VRNPQ 835
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 45.1 bits (105), Expect = 2e-04
Identities = 88/363 (24%), Positives = 123/363 (33%), Gaps = 67/363 (18%)
Query: 68 ESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGA 127
E ESE E+G +E GT +A A PA P P +
Sbjct: 267 EEESESSEEGSES--EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324
Query: 128 TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASA-------GPLHLSVPGPGPAWENPER 180
T E S S S E A A G PA E+P +
Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384
Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKK 239
G+ + P A+ AG +DS S+ E SD S +E +QAKP S K
Sbjct: 385 GAAPAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKA 433
Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG 299
P S +ES + P +PPR+ P + VG+ + S +
Sbjct: 434 PQVRAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE------- 481
Query: 300 VRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359
R L A + K L +P++ PAS
Sbjct: 482 -----------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS-- 510
Query: 360 PVSGVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQK 417
G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+
Sbjct: 511 -TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE 569
Query: 418 PEL 420
L
Sbjct: 570 KSL 572
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%)
Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171
+PP V G +P K D + E S G + + Q+ S G + + P
Sbjct: 524 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582
Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231
PA P++ ++ QV ++P D+S+S++ESSD + +Q
Sbjct: 583 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 631
Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291
AKP C +++ ++P R T +
Sbjct: 632 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 671
Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350
P+ S AV G R ++E S E LA+ G + G+ L
Sbjct: 672 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724
Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410
A+ PV G LG+ P P + P + +E ++ E++D
Sbjct: 725 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778
Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470
AQ+ T SV++ + + RAP GT + S +PP
Sbjct: 779 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830
Query: 471 VHPPR 475
V P+
Sbjct: 831 VRNPQ 835
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 45.1 bits (105), Expect = 2e-04
Identities = 90/416 (21%), Positives = 132/416 (31%), Gaps = 68/416 (16%)
Query: 109 PATIMPPSSVQGHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSV 168
PAT P +G P+P AT PS +G L+ P + + P ++
Sbjct: 1255 PATPPP----KGAPTPPAATP-------------PSLKGGLATPP---HKGAPNPAVVTP 1294
Query: 169 PGP--GPAWENPERGSKSRLSFQVDPQ-QPSAEGPAGLNTDDSDSADESSDLPVIRVIIS 225
P P GPA P+ + P+ P P G T + + P +
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354
Query: 226 TKEGSQAKPGS---PKKPGDTCGRRSFHRRESYLQVQGPLLISP-------------PRR 269
+ +G P S P P T + +GP + SP P++
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Query: 270 L--TPVVER----PAVGELDVP-----SLKKMQSMVWGKRG-VRPSCSG----AAVRGPL 313
TPV P+ G+L P SLKK + K G PS G AV P
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474
Query: 314 PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRP 373
P+ A ++ + +P+ A P L AV P P + P
Sbjct: 1475 PK----EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP----SSRRDP 1526
Query: 374 KEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSG 433
P + KK + P+ + P P + P S + +S
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS-----SKEASS 1581
Query: 434 DPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQQPPGAQGCP 489
P + G P + V P V PP PE+ P +G P
Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Score = 32.3 bits (72), Expect = 1.0
Identities = 52/220 (23%), Positives = 75/220 (34%), Gaps = 27/220 (12%)
Query: 302 PSCSGAAVRGP-LPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360
P+ G+A GP P G L V+ + S L+ +G+ + S PP P P
Sbjct: 809 PTKKGSA--GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 361 VSGVGLL---GKSVRPKE---------------PKHSSPGKKPAGRKTRESQAAAREDND 402
S V L G ++ PKE P +P + PA T S AR
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 403 PNRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHA 462
P +P + P P + G P +P+ T + + P +
Sbjct: 927 PK--GIPASPSPKGAP---TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS 981
Query: 463 SSGDWQPP-VHPPRPERQQQPPGAQGCPRVMLCVAPRNRG 501
G PP PP P+ P +G P P +G
Sbjct: 982 PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 43.1 bits (100), Expect = 6e-04
Identities = 103/424 (24%), Positives = 131/424 (30%), Gaps = 78/424 (18%)
Query: 14 LGPEG--GEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71
+GP G GE+ + +PG P G + G G KG+ GF P
Sbjct: 1438 VGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGP-KGDRGFPGP----LGEAG 1492
Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131
E E+G G G PG A G P P+ QG G G
Sbjct: 1493 EKGERGPPGPAGSRGLPGVAGRPGAKG----------PEGPPGPTGRQGEKGEPGRP--G 1540
Query: 132 STDIWADLEVGPSWR----GALSPSPGEWQQASAGPLHLSVPG-PGPAWENPERG----- 181
+ GP G P Q GP L +PG PGP + +RG
Sbjct: 1541 DPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLT 1600
Query: 182 -------SKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKP 234
+ DP +P GP G D + + +G + P
Sbjct: 1601 GRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE---------------KGDEGPP 1645
Query: 235 GSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGE--LDVPSLKKMQS 292
G P PG G R L P PV E+ G+ D + S
Sbjct: 1646 GDPGLPG-KAGERG--------------LRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSS 1690
Query: 293 MVWGKRGVRPSCSGAAVR------GPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQ 346
G RG P G R G +G G + + + +G P L GA G
Sbjct: 1691 GPKGDRG-EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP--GLPGAPGERGI 1747
Query: 347 RLSAVPPDPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNR 405
PP P P V G G G P S KP AA + DP R
Sbjct: 1748 EGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGR 1807
Query: 406 DEVP 409
D +P
Sbjct: 1808 DGLP 1811
Score = 42.0 bits (97), Expect = 0.001
Identities = 108/446 (24%), Positives = 140/446 (31%), Gaps = 84/446 (18%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGH-GRDLNFGGQRSGKGKGKGESGFTDPESFSFESESEL 73
GP G A PGA G GR N G G KG G P
Sbjct: 1287 GPPGSATAKGERGFPGADGRPGSPGRAGNPG--TPGAPGLKGSPGLPGPRG--------- 1335
Query: 74 IEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPS--SVQGHPSPEGATAKG 131
+ G G +G PG P G G +P PP G P P G
Sbjct: 1336 -DPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLP 1394
Query: 132 STDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVD 191
T + D + + GP PGPG P L
Sbjct: 1395 GTAMKGD----------------KGDRGERGP-----PGPGEGGIAPGEPGLPGLPGSPG 1433
Query: 192 PQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHR 251
PQ P GP G + DS D + LP + ++G + PG+ GD G
Sbjct: 1434 PQGPV--GPPGKKGEKGDSEDGAPGLPG-QPGSPGEQGPRGPPGAIGPKGDR-GFPGPLG 1489
Query: 252 RESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG--VRPSCSGAAV 309
+GP + R L V RP + P + G+ G P+ G AV
Sbjct: 1490 EAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAV 1549
Query: 310 RGPLPR----GTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSG-V 364
GP G G + A + G P L L G P P P G +
Sbjct: 1550 AGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPG------------DPGPKGDPGDRGPI 1597
Query: 365 GLLGKSVRPKEPKHSSPGKK----------PAGRKTRESQAAAREDNDPNRDEVPRAQLP 414
GL G++ P + PG+K P G + R+ + + D P D
Sbjct: 1598 GLTGRAGPPGD--SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGD-------- 1647
Query: 415 TQKPELISLSVRRGEYSSGDPNIRAP 440
P L + RG G P +R P
Sbjct: 1648 ---PGLPGKAGERG--LRGAPGVRGP 1668
Score = 42.0 bits (97), Expect = 0.001
Identities = 62/218 (28%), Positives = 74/218 (33%), Gaps = 29/218 (13%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGD------GHGRDLNFGGQRSGKGKG--KGESGFTDP 62
R LGP+G A PG+P D G D+ F G R KG+ KG G
Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGE 2639
Query: 63 ESFSFESESELIEQGRVVLWGQEGRPGTP-VDDQAGG----------GDYSFYLADEPAT 111
+ + E GR L G +G G P V Q+G GD F P
Sbjct: 2640 KG----DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKG 2695
Query: 112 IMPPSSVQGHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPG- 170
+G P G D A P G P + Q+ GP V G
Sbjct: 2696 DQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGA 2755
Query: 171 PGPAWENPERGSKSRLSFQVDPQQPSAE-GPAGLNTDD 207
PG ERG + R P P E G A L DD
Sbjct: 2756 PGVPGAPGERGEQGR----PGPAGPRGEKGEAALTEDD 2789
Score = 37.7 bits (86), Expect = 0.025
Identities = 76/335 (22%), Positives = 102/335 (30%), Gaps = 73/335 (21%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74
GP+G G P GR L G G SG P+
Sbjct: 2198 GPQGPSGLKGEPGETGPP-----GRGLTGPTGAVGLPGPPGPSGLVGPQG---------- 2242
Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPAT--IMPPSSVQGHPSPEGATAKGS 132
G G+ G+PG P D A G D P + + P +G P P GA +
Sbjct: 2243 SPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAV 2302
Query: 133 TDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDP 192
L +GA G+ +PGP RG K +P
Sbjct: 2303 ----VGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGP--------RGEKGEAGRAGEP 2350
Query: 193 QQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRR 252
P +G G D +P GS PG P GD
Sbjct: 2351 GDPGEDGQKGAPGPKGFKGDPGVGVP----------GSPGPPGPPGVKGD---------- 2390
Query: 253 ESYLQVQG----PLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAA 308
L + G P ++ P + P GE+ P G+RG+
Sbjct: 2391 ---LGLPGLPGAPGVVGFPGQTGP------RGEMGQPGPS-------GERGLAGPPGREG 2434
Query: 309 VRGPL----PRGTLGRKVAQEKKSLEGAPELALRG 339
+ GPL P G++G A K +G P + L G
Sbjct: 2435 IPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPG 2469
Score = 35.8 bits (81), Expect = 0.093
Identities = 62/235 (26%), Positives = 74/235 (31%), Gaps = 66/235 (28%)
Query: 15 GPEGGEQAGAHTASPG--APRGD----GHGRDLNFGGQRSGKGKG--KGESGFTDPESFS 66
GP G + A S G P+GD G D G R G GE G PE
Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPE--- 2164
Query: 67 FESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEG 126
G+ L G G PG PV G PA PS ++G P
Sbjct: 2165 ----------GKPGLQGPRGPPG-PVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPG--- 2210
Query: 127 ATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRL 186
E GP RG P+ G + L P PGP+ +GS
Sbjct: 2211 -------------ETGPPGRGLTGPT---------GAVGLPGP-PGPSGLVGPQGSPGLP 2247
Query: 187 SFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241
+ +P A G G + D D GS PGSP PG
Sbjct: 2248 GQVGETGKPGAPGRDGASGKDGD------------------RGSPGVPGSPGLPG 2284
Score = 32.0 bits (71), Expect = 1.3
Identities = 116/491 (23%), Positives = 160/491 (32%), Gaps = 70/491 (14%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQ--RSGKGKGKGESGFTDPESFSFESESE 72
GP G + PGA G G R G +GE G P S +
Sbjct: 1773 GPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGP-SGPPGLPGK 1831
Query: 73 LIEQGRVVLWGQEGRPGTPVDDQAGG--GDYSFYLADEPATIMPPSSVQGHPSPEGATAK 130
E G+ L G+ G PG P +D G GD S +G P+G +
Sbjct: 1832 PGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSG------------ASGREGRDGPKG--ER 1877
Query: 131 GSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQV 190
G+ I + P G + P PG+ G G GP + E GSK Q
Sbjct: 1878 GAPGILGP-QGPPGLPGPVGP-PGQGFPGVPG-------GTGPKGDRGETGSKGE---QG 1925
Query: 191 DPQQPSAEGPAGLNTDDSDSADESSDL--PVIRVIISTKEGSQAK----PGSPKKPGDTC 244
P + G G + + D E++ + +R I+ T + S P + P
Sbjct: 1926 LPGERGLRGEPG-SVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984
Query: 245 GRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSC 304
G + +E + G ER G+ P + + G+RG P
Sbjct: 1985 GEQGPPGKEGPIGFPG--------------ERGLKGDRGDPGPQGPPGLALGERG-PPGP 2029
Query: 305 SGAAVRGPLP--RGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVS 362
SG A P G GR + G RG G+R P P
Sbjct: 2030 SGLAGEPGKPGIPGLPGRAGGVGEAGRPGE-----RGERGEKGERGEQGRDGPPGLPGTP 2084
Query: 363 G-VGLLGKSVRPKEPKHSSPGKK-PAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420
G G G V EP G++ P G K + + + D P D +P K +
Sbjct: 2085 GPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDR----GVPGIKGDR 2140
Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHP--PRPER 478
R + + G P R + G R P GD PP P P
Sbjct: 2141 GEPGPRGQDGNPGLPGERG--MAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198
Query: 479 QQQPPGAQGCP 489
Q P G +G P
Sbjct: 2199 PQGPSGLKGEP 2209
Score = 30.0 bits (66), Expect = 5.1
Identities = 120/522 (22%), Positives = 155/522 (29%), Gaps = 89/522 (17%)
Query: 15 GPEGGEQAGAHTASPG-------APRGD-GHGRDLNFGGQR-----SGKGKGKGESGFTD 61
GP G PG P+GD G + G+ SG KG+ G
Sbjct: 1563 GPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPG 1622
Query: 62 PESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSV--Q 119
P + +GR G++G G P D G L P P Q
Sbjct: 1623 PPG-------PVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQ 1675
Query: 120 GHPSPEGATAKGSTDIWADLEVGPSW-RGALSPSPGEWQQASAGPLHLSVPGPGPAWENP 178
G P +G + GP RG P + GP PG +
Sbjct: 1676 GDPGEDGRNGSPGSS-------GPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEG 1728
Query: 179 ERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTK----------- 227
RG K DP P A G G+ + P +R K
Sbjct: 1729 PRGPKG------DPGLPGAPGERGIEGFRGPPGPQGD--PGVRGPAGEKGDRGPPGLDGR 1780
Query: 228 EGSQAKPGS--PKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVP 285
G KPG+ P P G+ R+ ++G + P + +P GE P
Sbjct: 1781 SGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKP--GEDGKP 1838
Query: 286 SLKKMQSMVWGKRGVRPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-------AL 337
L GK G +G G GR+ K GAP + L
Sbjct: 1839 GLN-------GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGL 1891
Query: 338 RGAFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKE-PKHSSPGKKPAGRKTRES--- 393
G GQ VP G G+ P E PG P + E+
Sbjct: 1892 PGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGI 1951
Query: 394 QAAAREDNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTL 453
+A+A + DE + LP PE RRG GD + P G P F
Sbjct: 1952 KASALREIVETWDESSGSFLPV--PER-----RRG--PKGDSGEQGPP--GKEGPIGFPG 2000
Query: 454 RRLVPRCHASSGDWQPP------VHPPRPERQQQPPGAQGCP 489
R + G PP PP P PG G P
Sbjct: 2001 ERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIP 2042
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 42.4 bits (98), Expect = 0.001
Identities = 118/494 (23%), Positives = 152/494 (30%), Gaps = 110/494 (22%)
Query: 13 GLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESE 72
G GP+G T G P G G D KG++G P+
Sbjct: 601 GPGPQGPPGKNGETGPQGPPGPTGPGGD-------------KGDTGPPGPQ--------- 638
Query: 73 LIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGS 132
G +G PGT GG EP P G P G G
Sbjct: 639 ----------GLQGLPGT------GGPPGENGKPGEPG----PKGDAGAPGAPG----GK 674
Query: 133 TDIWADLEVG-------PSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENP------- 178
D A E G P RG P E + +AGP PGP A P
Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP-----PGPPGAAGTPGLQGMPG 729
Query: 179 ERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPK 238
ERG + D +P G G+ D P+ + + G + + G+P
Sbjct: 730 ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG---PIGPPGPAGQPGDKGEGGAPG 786
Query: 239 KPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKR 298
PG G R GP P E GE P K G
Sbjct: 787 LPG-IAGPRGSPGERGETGPPGP--AGFPGAPGQNGEPGGKGERGAPGEKG----EGGPP 839
Query: 299 GVRPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPAS 357
GV G+ GP P+G G + + G P RG G + PP P+
Sbjct: 840 GVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFP--GARGLPGPPGSNGNPGPPGPSG 897
Query: 358 FPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQ 416
P G G G + P P S P K AG+ P P AQ P
Sbjct: 898 SPGKDGPPGPAGNTGAPGSPGVSGP-KGDAGQ--------------PGEKGSPGAQGPPG 942
Query: 417 KPELISLSVRRGEYS-SGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPR 475
P + ++ G +G P + P+ G+ P P + SG
Sbjct: 943 APGPLGIAGITGARGLAGPPGMPGPR--GSPGPQGVKGESGKPGANGLSG---------- 990
Query: 476 PERQQQPPGAQGCP 489
++ PPG QG P
Sbjct: 991 ---ERGPPGPQGLP 1001
Score = 40.8 bits (94), Expect = 0.003
Identities = 56/234 (23%), Positives = 68/234 (29%), Gaps = 31/234 (13%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74
GP G + + G P DG+ G R G GKG+ G
Sbjct: 993 GPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG-RDGSPGGKGDRG---------------- 1035
Query: 75 EQGRVVLWGQEGRPGTP--VDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA-KG 131
E G G G PG P V GD PA P+ +G P P+G KG
Sbjct: 1036 ENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKG 1095
Query: 132 STDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVD 191
T G +PG ++ PGPA G
Sbjct: 1096 ETGERG--AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGT 1153
Query: 192 PQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCG 245
P GP G + + E S G PG P PG CG
Sbjct: 1154 SGHPGPIGPPGPRGNRGERGSEGSP---------GHPGQPGPPGPPGAPGPCCG 1198
Score = 35.8 bits (81), Expect = 0.093
Identities = 108/443 (24%), Positives = 134/443 (30%), Gaps = 83/443 (18%)
Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKG----KG-KGESGFTDPESF 65
R G GP G E PG P G G+R G G KG KGE G +
Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV 754
Query: 66 SFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLA------DEPATIMPPSSVQ 119
+ +G G G G P D GG +A E PP
Sbjct: 755 PGKDG----PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA- 809
Query: 120 GHPSPEGATAK--GSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWEN 177
G P G + G + A E G ++ PG AGP PGP
Sbjct: 810 GFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG--GSGPAGP-------PGPQGVK 860
Query: 178 PERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSP 237
ERGS P GP G N + GS K G P
Sbjct: 861 GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG---------------PSGSPGKDGPP 905
Query: 238 KKPGDTCGRRSFHRRESYLQVQGPL--LISPPRRLTPVVERP--AVGELDVPSLKKMQSM 293
G+T S V GP P + +P + P A G L + + + +
Sbjct: 906 GPAGNTGAPGS-------PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958
Query: 294 VWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPP 353
G G+ P PRG+ G Q K G P GA G+R PP
Sbjct: 959 A-GPPGM-----------PGPRGSPG---PQGVKGESGKP-----GANGLSGER---GPP 995
Query: 354 DPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQ 412
P P ++G G G+ P P G+ R + P P
Sbjct: 996 GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPV 1055
Query: 413 LPTQKPELISLSVRRGEYSSGDP 435
P K S RGE P
Sbjct: 1056 GPAGK------SGDRGESGPAGP 1072
Score = 35.0 bits (79), Expect = 0.16
Identities = 94/415 (22%), Positives = 129/415 (31%), Gaps = 84/415 (20%)
Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74
GP G H SPG+P G + G SG G G + P
Sbjct: 180 GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGP-SGPPGPPGAIGPSGPAGKD-------- 230
Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGSTD 134
G+ GRPG P + G P I P+ + G P +G +
Sbjct: 231 --------GESGRPGRPGERGLPG----------PPGIKGPAGIPGFPGMKGHRGFDGRN 272
Query: 135 IWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQ 194
P +G + PGE + GP+ GP ERG +
Sbjct: 273 GEKGETGAPGLKGE-NGLPGE--NGAPGPM-------GPRGAPGERG------------R 310
Query: 195 PSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGD-----------T 243
P G AG +D + P G+ PGSP G+
Sbjct: 311 PGLPGAAGARGNDGARGSDGQPGP------PGPPGTAGFPGSPGAKGEVGPAGSPGSNGA 364
Query: 244 CGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPS 303
G+R + + QGP PP + +G +P + G RG P
Sbjct: 365 PGQRGEPGPQGHAGAQGP--PGPPGINGSPGGKGEMGPAGIPGAPGLM----GARG-PPG 417
Query: 304 CSGA----AVRG----PLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDP 355
+GA +RG P G G + ++ G P + GA G+ S P
Sbjct: 418 PAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIP--GVPGAKGEDGKDGSPGEPGA 475
Query: 356 ASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAR-EDNDPNRDEVP 409
P +G P P K PAG + A R +P RD VP
Sbjct: 476 NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530
Score = 32.3 bits (72), Expect = 1.0
Identities = 78/314 (24%), Positives = 110/314 (35%), Gaps = 63/314 (20%)
Query: 83 GQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPS-PEGATAK-GSTDIWADLE 140
G +G PG P G P + PP + P+ P+ + + S D+ + +
Sbjct: 106 GPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVA 165
Query: 141 VGPSWRGALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRLSFQVDPQQPSAEG 199
VG L+ PG AGP PGP GP + GS +Q P +P G
Sbjct: 166 VG-----GLAGYPGP-----AGP-----PGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG 210
Query: 200 PAG-------LNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRR 252
P+G + D S P + G + PG P G G F
Sbjct: 211 PSGPPGPPGAIGPSGPAGKDGESGRP-------GRPGERGLPGPPGIKG-PAGIPGFPGM 262
Query: 253 ESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGP 312
+ + G GE P LK G+ G+ P +GA GP
Sbjct: 263 KGHRGFDG--------------RNGEKGETGAPGLK-------GENGL-PGENGAP--GP 298
Query: 313 L-PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGV-GLLGKS 370
+ PRG G + GA GA + GQ PP A FP G G +G +
Sbjct: 299 MGPRGAPGERGRPGLPGAAGA--RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356
Query: 371 VRPKEPKHSSPGKK 384
P + +PG++
Sbjct: 357 GSP--GSNGAPGQR 368
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 42.0 bits (97), Expect = 0.001
Identities = 69/339 (20%), Positives = 107/339 (31%), Gaps = 63/339 (18%)
Query: 150 SPSPGEWQQASAGPLHLSVPGPGPA------WENPERGSKSRLSFQVDPQQPSAEGPAGL 203
+PSP +++ A + +P P P+ E P + S P+A
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
Query: 204 NTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLL 263
A S + + G A+ G+P+ P + LQ P
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSAR-GTPRAPAHPS-----QPKPKGLQALRPPQ 284
Query: 264 ISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVA 323
++PPR+ PA+G L S + + P P GT R V
Sbjct: 285 VTPPRKDAA----PALGPL----------------------SSSPLATPSPSGTKARPVP 318
Query: 324 QEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGK 383
+ P A P L PP P++ P + + P + P +
Sbjct: 319 PPDNAATPLP--ATLPPSPPLATPLPLAPPSPSAPPSLQTL---------PSPPATPPSQ 367
Query: 384 KPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQ--------KPELISLSVRRGEYSSGDP 435
P T QA P+ +P Q+P P ++LS + S G P
Sbjct: 368 APPSMTTPPMQAP------PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Query: 436 NIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPP 474
++A T P P AS+ PP+ P
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 42.0 bits (97), Expect = 0.001
Identities = 74/346 (21%), Positives = 117/346 (33%), Gaps = 72/346 (20%)
Query: 109 PATIMPPSSVQGHPSPEGA--TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHL 166
P++ PPS+ Q P P + ++ ++ +D + S S E + PL
Sbjct: 445 PSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENE----PLET 500
Query: 167 SVPGPGPAWEN----------------PERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDS 210
P P P N P G +S +P + E ++ S
Sbjct: 501 PAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRS-----TEPPRRHPESKGSSDSATSQE 555
Query: 211 ADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRL 270
ES D P K S+A P+ P G+RS + P PP+R
Sbjct: 556 HSESKDPP-------PKSSSKAPRAPPEAPHP--GKRSCQK--------SPAQQEPPQRQ 598
Query: 271 TPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKK-SL 329
T ++P K + G R S G G LP G+ + + K
Sbjct: 599 TVGTKQP-----------KKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKT 647
Query: 330 EGAPELAL----RGAFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKH------- 378
+G P A + A P ++ PA +SG +V + P+H
Sbjct: 648 KGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLT 707
Query: 379 --SSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPELIS 422
P +G +T + A D +D +P LP + +L+S
Sbjct: 708 ESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLP---LPLRDTKLLS 750
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,383,451
Number of Sequences: 37866
Number of extensions: 1747858
Number of successful extensions: 7947
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 413
Number of HSP's that attempted gapping in prelim test: 6883
Number of HSP's gapped (non-prelim): 1407
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.