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Search of human proteins with 239757324
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757324 PREDICTED: hypothetical protein XP_002345241 [Homo
sapiens]
(582 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757324 PREDICTED: hypothetical protein XP_002345241 [Homo ... 1237 0.0
gi|239751831 PREDICTED: hypothetical protein XP_002348009 [Homo ... 1207 0.0
gi|239746324 PREDICTED: hypothetical protein XP_002343730 [Homo ... 646 0.0
gi|239746322 PREDICTED: hypothetical protein XP_002343729 [Homo ... 452 e-127
gi|239757352 PREDICTED: similar to LMARRLC1A [Homo sapiens] 59 1e-08
gi|239751859 PREDICTED: similar to LMARRLC1A [Homo sapiens] 58 2e-08
gi|239746350 PREDICTED: hypothetical protein XP_002343735 [Homo ... 58 2e-08
gi|60097902 filaggrin [Homo sapiens] 49 1e-05
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 48 2e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 48 2e-05
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 48 3e-05
gi|57864582 hornerin [Homo sapiens] 45 2e-04
gi|62122917 filaggrin family member 2 [Homo sapiens] 44 4e-04
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 44 5e-04
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 44 5e-04
gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo ... 43 0.001
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 42 0.001
gi|239757829 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239752340 PREDICTED: hypothetical protein XP_002348205 [Homo ... 42 0.002
gi|239746853 PREDICTED: hypothetical protein XP_002343864 [Homo ... 42 0.002
gi|239755481 PREDICTED: similar to Putative uncharacterized prot... 42 0.002
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 41 0.003
gi|14249622 ajuba isoform 1 [Homo sapiens] 40 0.006
gi|11386161 alpha 2 type IX collagen [Homo sapiens] 40 0.006
gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens] 40 0.008
gi|22027605 alpha 1 type XIII collagen isoform 17 [Homo sapiens] 40 0.008
gi|22027601 alpha 1 type XIII collagen isoform 15 [Homo sapiens] 40 0.008
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 40 0.008
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 39 0.010
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 39 0.010
>gi|239757324 PREDICTED: hypothetical protein XP_002345241 [Homo
sapiens]
Length = 582
Score = 1237 bits (3201), Expect = 0.0
Identities = 582/582 (100%), Positives = 582/582 (100%)
Query: 1 MANQQQNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVV 60
MANQQQNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVV
Sbjct: 1 MANQQQNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVV 60
Query: 61 GCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVV 120
GCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVV
Sbjct: 61 GCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVV 120
Query: 121 HHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGT 180
HHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGT
Sbjct: 121 HHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGT 180
Query: 181 ESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGT 240
ESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGT
Sbjct: 181 ESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGT 240
Query: 241 HPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPIL 300
HPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPIL
Sbjct: 241 HPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPIL 300
Query: 301 VADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQG 360
VADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQG
Sbjct: 301 VADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQG 360
Query: 361 VQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPA 420
VQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPA
Sbjct: 361 VQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPA 420
Query: 421 KGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDC 480
KGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDC
Sbjct: 421 KGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDC 480
Query: 481 KDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPA 540
KDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPA
Sbjct: 481 KDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPA 540
Query: 541 QGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 582
QGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG
Sbjct: 541 QGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 582
>gi|239751831 PREDICTED: hypothetical protein XP_002348009 [Homo
sapiens]
Length = 589
Score = 1207 bits (3122), Expect = 0.0
Identities = 570/587 (97%), Positives = 573/587 (97%), Gaps = 12/587 (2%)
Query: 8 LVSTGSNRRE------------EEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ 55
L++TGS + E EEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ
Sbjct: 3 LIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ 62
Query: 56 PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG 115
PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG
Sbjct: 63 PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG 122
Query: 116 GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE 175
GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE
Sbjct: 123 GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE 182
Query: 176 AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE 235
AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE
Sbjct: 183 AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE 242
Query: 236 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA 295
QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA
Sbjct: 243 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA 302
Query: 296 VIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGK 355
VIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGK
Sbjct: 303 VIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGK 362
Query: 356 GDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDA 415
GDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDA
Sbjct: 363 GDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDA 422
Query: 416 AGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSH 475
AGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSH
Sbjct: 423 AGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSH 482
Query: 476 QEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGS 535
QEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGS
Sbjct: 483 QEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGS 542
Query: 536 KVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 582
KVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG
Sbjct: 543 KVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 589
>gi|239746324 PREDICTED: hypothetical protein XP_002343730 [Homo
sapiens]
Length = 329
Score = 646 bits (1667), Expect = 0.0
Identities = 302/321 (94%), Positives = 305/321 (95%), Gaps = 12/321 (3%)
Query: 8 LVSTGSNRRE------------EEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ 55
L++TGS + E EEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ
Sbjct: 3 LIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ 62
Query: 56 PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG 115
PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG
Sbjct: 63 PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG 122
Query: 116 GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE 175
GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE
Sbjct: 123 GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE 182
Query: 176 AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE 235
AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE
Sbjct: 183 AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE 242
Query: 236 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA 295
QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA
Sbjct: 243 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA 302
Query: 296 VIPILVADRIVPHSGSWVSPT 316
VIPILVADRIVPHSGSW PT
Sbjct: 303 VIPILVADRIVPHSGSWCEPT 323
Score = 93.2 bits (230), Expect = 6e-19
Identities = 61/169 (36%), Positives = 78/169 (46%), Gaps = 3/169 (1%)
Query: 347 VDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHV 406
V AVD G Q Q G A P P + Q+ VG + QEQDAG+H
Sbjct: 140 VQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHG 199
Query: 407 EQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPD 466
+QD+GGQ PV NG QDGQRQ +++ + QVE+P G P G HP
Sbjct: 200 QQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPG 259
Query: 467 HQGIAQHSHQED---DCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIV 512
H GIA+H HQED + Q V +HR V ++ I+V
Sbjct: 260 HHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILV 308
>gi|239746322 PREDICTED: hypothetical protein XP_002343729 [Homo
sapiens]
Length = 221
Score = 452 bits (1162), Expect = e-127
Identities = 212/213 (99%), Positives = 212/213 (99%)
Query: 370 DPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYN 429
DPGQA PSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYN
Sbjct: 9 DPGQASPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYN 68
Query: 430 GREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDVW 489
GREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDVW
Sbjct: 69 GREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDVW 128
Query: 490 NTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPAQGLWFLKPQ 549
NTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPAQGLWFLKPQ
Sbjct: 129 NTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPAQGLWFLKPQ 188
Query: 550 GKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 582
GKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG
Sbjct: 189 GKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 221
Score = 90.9 bits (224), Expect = 3e-18
Identities = 53/142 (37%), Positives = 70/142 (49%), Gaps = 3/142 (2%)
Query: 160 ARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQ 219
A P P + Q+ VG + QEQDAG+H +QD+GGQ PV NG Q
Sbjct: 13 ASPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQ 72
Query: 220 DGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 279
DGQRQ +++ + QVE+P G P G HP H GIA+H HQED + Q V
Sbjct: 73 DGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQED---DCKDDQGQDVWN 129
Query: 280 QAGAIQAVHRAVREVAVIPILV 301
+HR V ++ I+V
Sbjct: 130 TQRVRSFIHRGVEVQGILVIIV 151
>gi|239757352 PREDICTED: similar to LMARRLC1A [Homo sapiens]
Length = 279
Score = 58.9 bits (141), Expect = 1e-08
Identities = 36/117 (30%), Positives = 55/117 (47%)
Query: 372 GQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGR 431
GQA + VL PD + AV ++ G ++D V+ G ++ A PA+ P+
Sbjct: 134 GQAHGAVVLGPDWMQDANTAVQSNEGDQEDTSEQVDVHYGKEEFAQEPAERPMSSHGLPD 193
Query: 432 EQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDV 488
++ Q EV + QV+ DG D E HPDH+ +AQ + DCK D+
Sbjct: 194 HEEWQSGGETEVSHGQVQVTDGGDCVCHPESSHPDHKPVAQDPEDKGDCKYQISDDI 250
Score = 40.4 bits (93), Expect = 0.005
Identities = 51/197 (25%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 87 GTVAAGHGHQGPQEAKKKPD-GSHRILGAGGAAVVHHTLQPGWEVLLVQPA--------- 136
G + + G EA +PD SHR G G + + PG +V
Sbjct: 53 GPITDSNDGHGCAEANDEPDDASHRQHGNGHLYPLFRVVGPGRKVKSAGYCPRFTRYCSH 112
Query: 137 VDGGGHGEQQGQCPGCPTGHL----HPARPLNRRPPGRPESQEAEVGTESCQE---QDAG 189
+ E+Q PG P HL H A L P ++ A E QE +
Sbjct: 113 TNDNWQCEEQSHHPG-PNDHLLGQAHGAVVLG--PDWMQDANTAVQSNEGDQEDTSEQVD 169
Query: 190 IHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPS 249
+H +++ Q P RP++S G ++ Q ++ HGQV+ G S
Sbjct: 170 VHYGKEEFAQEPAE----RPMSSHGLPDHEEWQSGGETEVSHGQVQVTDGGDCVCHPESS 225
Query: 250 HPGHHGIARHPHQEDGG 266
HP H +A+ P ED G
Sbjct: 226 HPDHKPVAQDP--EDKG 240
>gi|239751859 PREDICTED: similar to LMARRLC1A [Homo sapiens]
Length = 279
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/117 (30%), Positives = 54/117 (46%)
Query: 372 GQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGR 431
GQA + VL PD + AV ++ G ++D V+ G + A PA+ P+
Sbjct: 134 GQAHGAVVLGPDWMQDANTAVQSNEGDQEDTSEQVDVHYGKDEFAQEPAERPMSSHGLPD 193
Query: 432 EQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDV 488
++ Q EV + QV+ DG D E HPDH+ +AQ + DCK D+
Sbjct: 194 HEEWQSGGETEVSHGQVQVTDGGDCVCHPESSHPDHKPVAQDPEDKGDCKYQISDDI 250
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/197 (26%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 87 GTVAAGHGHQGPQEAKKKPD-GSHRILGAGGAAVVHHTLQPGWEVLLVQPA--------- 136
G + + G EA +PD SHR G G + + PG +V
Sbjct: 53 GPITDSNDGHGCAEANDEPDDASHRQHGNGHIYPLFRVVGPGRKVKSAGYCPRFTRYCSH 112
Query: 137 VDGGGHGEQQGQCPGCPTGHL----HPARPLNRRPPGRPESQEAEVGTESCQE---QDAG 189
+ E+Q PG P HL H A L P ++ A E QE +
Sbjct: 113 TNDNWQCEEQSHHPG-PNDHLLGQAHGAVVLG--PDWMQDANTAVQSNEGDQEDTSEQVD 169
Query: 190 IHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPS 249
+H +D+ Q P RP++S G ++ Q ++ HGQV+ G S
Sbjct: 170 VHYGKDEFAQEPAE----RPMSSHGLPDHEEWQSGGETEVSHGQVQVTDGGDCVCHPESS 225
Query: 250 HPGHHGIARHPHQEDGG 266
HP H +A+ P ED G
Sbjct: 226 HPDHKPVAQDP--EDKG 240
>gi|239746350 PREDICTED: hypothetical protein XP_002343735 [Homo
sapiens]
Length = 279
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/117 (30%), Positives = 54/117 (46%)
Query: 372 GQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGR 431
GQA + VL PD + AV ++ G ++D V+ G + A PA+ P+
Sbjct: 134 GQAHGAVVLGPDWMQDANTAVQSNEGDQEDTSEQVDVHYGKDEFAQEPAERPMSSHGLPD 193
Query: 432 EQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDV 488
++ Q EV + QV+ DG D E HPDH+ +AQ + DCK D+
Sbjct: 194 HEEWQSGGETEVSHGQVQVTDGGDCVCHPESSHPDHKPVAQDPEDKGDCKYQISDDI 250
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/197 (26%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 87 GTVAAGHGHQGPQEAKKKPD-GSHRILGAGGAAVVHHTLQPGWEVLLVQPA--------- 136
G + + G EA +PD SHR G G + + PG +V
Sbjct: 53 GPITDSNDGHGCAEANDEPDDASHRQHGNGHIYPLFRVVGPGRKVKSAGYCPRFTRYCSH 112
Query: 137 VDGGGHGEQQGQCPGCPTGHL----HPARPLNRRPPGRPESQEAEVGTESCQE---QDAG 189
+ E+Q PG P HL H A L P ++ A E QE +
Sbjct: 113 TNDNWQCEEQSHHPG-PNDHLLGQAHGAVVLG--PDWMQDANTAVQSNEGDQEDTSEQVD 169
Query: 190 IHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPS 249
+H +D+ Q P RP++S G ++ Q ++ HGQV+ G S
Sbjct: 170 VHYGKDEFAQEPAE----RPMSSHGLPDHEEWQSGGETEVSHGQVQVTDGGDCVCHPESS 225
Query: 250 HPGHHGIARHPHQEDGG 266
HP H +A+ P ED G
Sbjct: 226 HPDHKPVAQDP--EDKG 240
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 49.3 bits (116), Expect = 1e-05
Identities = 117/534 (21%), Positives = 174/534 (32%), Gaps = 115/534 (21%)
Query: 10 STGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPH 69
ST ++ HG + S G+ +G + G G H H Q +D
Sbjct: 2453 STSQEGQDTIHGHPGSSSGGR---QGSHYEQLVDRSGHSGSHHSHTTSQG---RSDASHG 2506
Query: 70 HNGC--AQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGS-HRILGAGGAAVVHHTLQP 126
H+G A R + + +G+ +G H EA + D S H +G G + +
Sbjct: 2507 HSGSRSASRQTRNDEQSGDGSRHSGSRHH---EASSRADSSGHSQVGQGQSEGPRTSRN- 2562
Query: 127 GWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPA-----RPLNRRPPGRPESQEAEVGTE 181
W Q + D GH E + G + + H + R +R P E + +
Sbjct: 2563 -WGSSFSQDS-DSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSA 2620
Query: 182 SCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTH 241
Q H Q GGQ ++H R +S G H Q Q+A RH G H
Sbjct: 2621 DSSRQSGTRHTQTSSGGQAASSHEQAR--SSAGERHGSHHQ-QSADSSRHS-----GIGH 2672
Query: 242 PPAGHLPSHPGHHGIA------RHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA 295
A GH G + H ED Q H GQAG+ Q H+
Sbjct: 2673 GQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAH-----GQAGSHQQSHQESARGR 2727
Query: 296 VIPILVADRIVPHSGS----------------WVSPT-------------ESCQHVPEEA 326
+ HSGS W P+ +S +H +
Sbjct: 2728 ------SGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQD 2781
Query: 327 GE----GFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGP------ 376
G+ G P S+ G+H + VD++ G + + + GQ+G
Sbjct: 2782 GQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQ-GRSDASRGQSGSRSASRT 2840
Query: 377 --SEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQD 434
+E + DG +H G + +A H + Q A G ++G
Sbjct: 2841 TRNEEQSGDGSRH-------SGSRHHEASTHADISRHSQ-AVQGQSEG----------SR 2882
Query: 435 GQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQ----------HSHQED 478
R+ G V E D +H G AQ SHQED
Sbjct: 2883 RSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQED 2936
Score = 45.8 bits (107), Expect = 1e-04
Identities = 74/310 (23%), Positives = 102/310 (32%), Gaps = 44/310 (14%)
Query: 6 QNLVSTGSNR-----REEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVV 60
Q+ STG + + ++ +A EG+ G PG G GR HQ +Q V
Sbjct: 2106 QSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGH----PGPSRG--GRQGSHQ-EQSV 2158
Query: 61 GCPADKKPHHNGCAQRPAASGCPAQEGTVAA------------GHGHQGPQ--EAKKKPD 106
HH+ + + Q G+ +A G H G EA D
Sbjct: 2159 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD 2218
Query: 107 GSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLH-----PAR 161
S L G + T +P V D GH E + G + + H +R
Sbjct: 2219 SSRHSLVGQGQSSGPRTSRPRGSS--VSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSR 2276
Query: 162 PLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAST--GNGHCQ 219
+R P E + + Q H + GGQ ++H R A G+ H Q
Sbjct: 2277 DGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQ 2336
Query: 220 DGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 279
I HGQ +GH S G H ED Q H G
Sbjct: 2337 SADSSRHSGIGHGQA---SSAVRDSGHRGS-SGSQASDSEGHSEDSDTQSVSAH-----G 2387
Query: 280 QAGAIQAVHR 289
QAG Q H+
Sbjct: 2388 QAGPHQQSHQ 2397
Score = 43.1 bits (100), Expect = 7e-04
Identities = 70/302 (23%), Positives = 95/302 (31%), Gaps = 36/302 (11%)
Query: 11 TGSNRREEEHGIEAA-VSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPH 69
T + RR+ H +A S A EG RGR H +Q V H
Sbjct: 3405 TSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHY-EQSVDRSGHSGSH 3463
Query: 70 HNGCAQRPAASGCPAQEGTVAAG--------------HGHQGPQEAKKKPDGS-HRILGA 114
H+ + + Q G+ +A H EA + D S H G
Sbjct: 3464 HSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQ 3523
Query: 115 GGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH-----LHPARPLNRRPPG 169
G +A + G V D GH E + G + + +R +R P
Sbjct: 3524 GQSAGPRTSRNQGSSV---SQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTS 3580
Query: 170 RPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAST--GNGHCQDGQRQTAQ 227
E + + Q H + GGQ ++H R A G+ H Q
Sbjct: 3581 HHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS 3640
Query: 228 QIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAV 287
I HGQ +GH S G H ED Q H GQAG Q
Sbjct: 3641 GIGHGQA---SSAVRDSGHRGS-SGSQASDSEGHSEDSDTQSVSAH-----GQAGPHQQS 3691
Query: 288 HR 289
H+
Sbjct: 3692 HQ 3693
Score = 40.4 bits (93), Expect = 0.005
Identities = 66/275 (24%), Positives = 90/275 (32%), Gaps = 45/275 (16%)
Query: 41 PGQECGVR-GRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA-------- 91
PG G R G H EH V HH+ + + Q G+ +A
Sbjct: 2790 PGSSRGGRQGYHHEHS----VDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 2845
Query: 92 ----GHGHQGPQ--EAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQ 145
G H G + EA D S G + + + + V D GH E
Sbjct: 2846 QSGDGSRHSGSRHHEASTHADISRHSQAVQGQS--EGSRRSRRQGSSVSQDSDSEGHSED 2903
Query: 146 QGQCPGCPTGHLHPA-----RPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 200
+ G + + H + R +R P E + + Q H Q GGQ
Sbjct: 2904 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQA 2963
Query: 201 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIA--- 257
++H R +S G H Q Q+A RH G H A GH G +
Sbjct: 2964 ASSHEQAR--SSAGERHGSHHQ-QSADSSRHS-----GIGHGQASSAVRDSGHRGYSGSQ 3015
Query: 258 ---RHPHQEDGGIQWERGHAQRVDGQAGAIQAVHR 289
H ED Q H GQAG+ Q H+
Sbjct: 3016 ASDNEGHSEDSDTQSVSAH-----GQAGSHQQSHQ 3045
Score = 38.5 bits (88), Expect = 0.017
Identities = 86/409 (21%), Positives = 130/409 (31%), Gaps = 67/409 (16%)
Query: 41 PGQECGVR-GRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQ 99
PG G R G H EH V HH+ + + Q G+ +A + +
Sbjct: 3114 PGSSRGGRQGYHHEHS----VDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 3169
Query: 100 EAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHP 159
++ D S + HH ++ AV G G ++ + G
Sbjct: 3170 QSG---DSSRHSVSR------HHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQ--- 3217
Query: 160 ARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQ 219
+ G E E G+ S + + Q G + P +H R G+GH
Sbjct: 3218 ----DSDSEGHSEDSERWSGSAS-RNHRGSVQEQSRHGSRHPRSHHEDR----AGHGHSA 3268
Query: 220 DGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 279
D RQ+ RH + G S PG +RH D H+ G
Sbjct: 3269 DRSRQSGT--RHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS-----RHSGIPRG 3321
Query: 280 QAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSAL-EAL 338
QA + AVR+ R SGS S +E + E QS
Sbjct: 3322 QASS------AVRD---------SRHWGSSGSQASDSEG------HSEESDTQSVSGHGQ 3360
Query: 339 AGHHVDDGVDAAVD--VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG 396
AG H ++A D G+ G L Q + ++ G + G+
Sbjct: 3361 AGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTG-----RRQGSHH 3415
Query: 397 GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGY 445
Q +D+ H EG G P GR+ Q+ + G+
Sbjct: 3416 EQARDSSRHSASQEGQDTIRGHPGSS-----RRGRQGSHYEQSVDRSGH 3459
Score = 36.6 bits (83), Expect = 0.065
Identities = 97/515 (18%), Positives = 156/515 (30%), Gaps = 105/515 (20%)
Query: 41 PGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA--------- 91
PG G GR H +Q V HH+ + + Q G+ +A
Sbjct: 520 PGSSRG--GRQGSHH-EQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQ 576
Query: 92 ---GHGHQGPQ--EAKKKPDGS-HRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQ 145
G H G + EA + D S H +G G ++ + G V D GH E
Sbjct: 577 SGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSV---SQDSDSQGHSED 633
Query: 146 QGQCPGCPTGHLH-----PARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 200
+ G + + H +R +R P E + + + H Q GQ
Sbjct: 634 SERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQA 693
Query: 201 PTAHCTIRPVAS-------------------TGNGHCQDGQRQTAQQIRHGQVEQPGGTH 241
++H R A TG+G R + + G H
Sbjct: 694 ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGH 753
Query: 242 PPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILV 301
S GH + GH Q+ ++ ++ R+ R + + +
Sbjct: 754 SEDSDTQSVSGH---------------GQAGHHQQSHQESARDRSGERSRRSGSFLYQVS 798
Query: 302 ADRIVPHSGSWVSPT-------------ESCQHVPEEAGE----GFPQSALEALAGHHVD 344
+ S W P+ ++ +H + G+ G P S+ G H +
Sbjct: 799 THKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHE 858
Query: 345 DGVDAAVDVGK--GDTQGVQLIQQQEGDPGQAGPSEVLAPD----------GFKHQQKAV 392
VD + G T G G S + G +H + +
Sbjct: 859 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASS 918
Query: 393 GADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAG----EEVGYRQV 448
AD + AG Q EG + + + G +D +R +G G Q
Sbjct: 919 HADISRHSQAG--QGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQE 976
Query: 449 EEPDGIDGPLGLECRHP--DHQGIAQHSHQEDDCK 481
+ G RHP H+ A H H D +
Sbjct: 977 QSRHG--------SRHPRSHHEDRAGHGHSADSSR 1003
Score = 36.6 bits (83), Expect = 0.065
Identities = 62/264 (23%), Positives = 88/264 (33%), Gaps = 35/264 (13%)
Query: 48 RGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA------------GHGH 95
RGR H +Q V HH+ + + Q G+ +A G H
Sbjct: 850 RGRQGSHH-EQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRH 908
Query: 96 QGPQ--EAKKKPDGS-HRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGC 152
G + EA D S H G G + + + G V D GH E + G
Sbjct: 909 SGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSV---SQDSDSEGHSEDSERWSGS 965
Query: 153 PTGH-----LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTI 207
+ + +R +R P E + + Q H + GGQ ++H
Sbjct: 966 ASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQA 1025
Query: 208 RPVASTGNGHCQDGQRQTAQQIRHGQV--EQPGGTHPPAGHLPSHPGHHGIARHPHQEDG 265
R +S G H Q Q+A RH + Q +GH S G H E+
Sbjct: 1026 R--SSPGERHGSRHQ-QSADSSRHSGIPRRQASSAVRDSGHWGS-SGSQASDSEGHSEES 1081
Query: 266 GIQWERGHAQRVDGQAGAIQAVHR 289
Q GH GQ G Q H+
Sbjct: 1082 DTQSVSGH-----GQDGPHQQSHQ 1100
Score = 32.7 bits (73), Expect = 0.94
Identities = 88/437 (20%), Positives = 128/437 (29%), Gaps = 83/437 (18%)
Query: 21 GIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAAS 80
GI + D G Q G HSE Q V PH + + +A
Sbjct: 1372 GIGHRQASSAVRDSGHRGSSGSQVTNSEG-HSEDSDTQSVSAHGQAGPHQQ--SHKESAR 1428
Query: 81 GCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGA----------AVVHHTLQPGWEV 130
G + + +Q + + GG + H Q G +
Sbjct: 1429 GQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDT 1488
Query: 131 LLVQPAVDGGG----HGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQ 186
+ P GG + EQ G +G+ H + P GR ++ + G S Q
Sbjct: 1489 IRGHPGSSRGGRQGSYHEQSVDRSG-HSGYHHS----HTTPQGRSDASHGQSGPRSASRQ 1543
Query: 187 DAGIHGQQDDGGQRPTAHCTIRPVASTGNG-HCQDGQRQTA-QQIRHGQVEQPGGTHPPA 244
+ +Q G R + P G+ H Q GQ ++A + Q
Sbjct: 1544 TR--NEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSE 1601
Query: 245 GHLPSHP--------GHHGIARHP----------HQEDGGIQWERGHAQRVDGQAGAIQA 286
GH H+G AR HQED GH+ Q+G A
Sbjct: 1602 GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRA---SHGHSAESSRQSGTRHA 1658
Query: 287 VHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVP-EEAGEGFPQSALEALAGHHVDD 345
+ G S E + P E G QSA
Sbjct: 1659 ETSS------------------GGQAASSQEQARSSPGERHGSRHQQSA----------- 1689
Query: 346 GVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVH 405
D++ D G G Q ++ GD G G S A D H +++ AG H
Sbjct: 1690 --DSSTDSGTGRRQDSSVV----GDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPH 1743
Query: 406 VEQDEGGQDAAGGPAKG 422
+ + G G
Sbjct: 1744 QQSHQESTRGQSGERSG 1760
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 48.1 bits (113), Expect = 2e-05
Identities = 124/494 (25%), Positives = 160/494 (32%), Gaps = 106/494 (21%)
Query: 29 GKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHH-NGCAQRPAASGCPAQEG 87
G + GF PG+ G G P+ + G P P +G A P A G P +G
Sbjct: 696 GPRGERGF----PGER-GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG 750
Query: 88 TV----AAGH----------GHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLV 133
AAG G +GP+ A K DG + G G EV
Sbjct: 751 MPGERGAAGIAGPKGDRGDVGEKGPEGAPGK-DGGRGLTGPIGPPGPAGANGEKGEVGPP 809
Query: 134 QPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGT--ESCQEQDAGIH 191
PA G G PG G P P P + Q G E+ Q+ DAG
Sbjct: 810 GPAGSAGARG-----APG-ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 863
Query: 192 GQQDDGG----QRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL 247
G Q G Q PT P + G Q T G+V PG P
Sbjct: 864 GPQGPSGAPGPQGPTG--VTGPKGARG---AQGPPGATGFPGAAGRVGPPGSNGNPGPPG 918
Query: 248 PSHP-------------GHHGIARHPH-QEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE 293
P P G G A P Q G E+G DG +GA
Sbjct: 919 PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD-DGPSGAEG-------- 969
Query: 294 VAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGE-GFPQSALEALAGHHVDDGVDAAVD 352
P ++ +P + GE GFP L G + G
Sbjct: 970 -------------PPGPQGLAGQRGIVGLPGQRGERGFP-----GLPGPSGEPG------ 1005
Query: 353 VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEG- 411
QG G PG GP + P G ++ + GADG +D V+ D G
Sbjct: 1006 -----KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE 1060
Query: 412 ----GQDAAGGPAKGPVVMLYNGREQDGQRQAGEE--------VGYRQVEEPDGIDGPLG 459
G A GP P G++ D + +AG + G R ++ P G G G
Sbjct: 1061 TGAVGAPGAPGPPGSPGPAGPTGKQGD-RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1119
Query: 460 LECRHPDHQGIAQH 473
E P +G+ H
Sbjct: 1120 -EAGEPGERGLKGH 1132
Score = 40.0 bits (92), Expect = 0.006
Identities = 90/389 (23%), Positives = 114/389 (29%), Gaps = 82/389 (21%)
Query: 77 PAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPA 136
P CP +A G GP+ K +P I+G G P P
Sbjct: 81 PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPP------GPQGPAGEQGPR 134
Query: 137 VDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDD 196
D G GE+ P G P P N PPG P + Q AG ++
Sbjct: 135 GDRGDKGEKGAPGPRGRDGE--PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192
Query: 197 GGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHP-----PAGHLPSHP 251
G Q + P+ G Q G+ +PG + P P G P P
Sbjct: 193 GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP-PGKP 251
Query: 252 GHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGS 311
G G A P G ERG G GA
Sbjct: 252 GDDGEAGKP-----GKAGERGPP----GPQGA---------------------------- 274
Query: 312 WVSPTESCQHVPEEAGEGFPQS-ALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGD 370
GFP + L + GH G+D A G+ GV+ G+
Sbjct: 275 ----------------RGFPGTPGLPGVKGHRGYPGLDGAK--GEAGAPGVKGESGSPGE 316
Query: 371 PGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNG 430
G GP G + + GA G + D + G GPA GP
Sbjct: 317 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDG----QPGPAGPPGPVGPAGGPGF----- 367
Query: 431 REQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
G A E G P+G GP G
Sbjct: 368 ---PGAPGAKGEAGPTGARGPEGAQGPRG 393
Score = 38.9 bits (89), Expect = 0.013
Identities = 109/446 (24%), Positives = 143/446 (32%), Gaps = 75/446 (16%)
Query: 40 GPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAG--HGHQG 97
GP G RG + P G P P G P A G + G A G QG
Sbjct: 336 GPAGAAGARGNDGQPGP---AGPPGPVGPA--GGPGFPGAPGAKGEAGPTGARGPEGAQG 390
Query: 98 PQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHL 157
P+ P GS GA G PG + + P G PG P G
Sbjct: 391 PRGEPGTP-GSPGPAGASG--------NPGTDGI---PGAKGSAGAPGIAGAPGFP-GPR 437
Query: 158 HPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGH 217
P P P P+ Q E G AG G+Q G+ G
Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGI-------AGFKGEQGPKGE-------------PGPAG 477
Query: 218 CQDGQRQTAQQIRHGQVEQPGGTHP--PAGHLPSHPGHHGIARHPHQEDG-----GIQWE 270
Q ++ + G +PGG P P G + PG+ G +DG G E
Sbjct: 478 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA-PGNRGFPG----QDGLAGPKGAPGE 532
Query: 271 RGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESC--QHVPEEAGE 328
RG + + G GA R P L R + P P E G
Sbjct: 533 RGPSG-LAGPKGANGDPGRPGE-----PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 586
Query: 329 GFP--------QSALEALAGHHVDDGVDA-AVDVGKGDTQGVQLIQQQEGDPGQAGPSEV 379
P Q + G +G A + G G++ + ++G+ G AGP
Sbjct: 587 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646
Query: 380 LAPDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGRE----Q 433
P G + +Q A G G G G E + G G A P ++ G +
Sbjct: 647 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706
Query: 434 DGQRQAGEEVGYRQVEEPDGIDGPLG 459
G A G R + G DGP G
Sbjct: 707 RGSPGAQGLQGPRGLPGTPGTDGPKG 732
Score = 33.9 bits (76), Expect = 0.42
Identities = 107/431 (24%), Positives = 134/431 (31%), Gaps = 59/431 (13%)
Query: 38 PQGPGQECGVRGRHSEHQPQQVVGCPA-DKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQ 96
PQGP E G RG + + G D +P G P G P G
Sbjct: 124 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL-------- 175
Query: 97 GPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH 156
G A + G G V+ + P PA G G Q PG P G
Sbjct: 176 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN--PGEP-GE 232
Query: 157 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNG 216
+ P+ R P P + + G E+ + AG G G R P G
Sbjct: 233 PGVSGPMGPRGPPGPPGKPGDDG-EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291
Query: 217 HCQ-DGQRQTAQQIR-HGQVEQPG--GTHPPAGH--LPSHPGHHGIARHPHQEDGGIQWE 270
+ DG + A G+ PG G+ P G LP G G A G
Sbjct: 292 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA--------GAAGA 343
Query: 271 RGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGF 330
RG+ DGQ G P + P G + G
Sbjct: 344 RGN----DGQPG---------------PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG 384
Query: 331 PQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQK 390
P+ A A G T G+ + G PG AG P G Q
Sbjct: 385 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444
Query: 391 AVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQV 448
A G G GQ + G+ + E G GPA GP Q AGEE
Sbjct: 445 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA-GP---------QGAPGPAGEEGKRGAR 494
Query: 449 EEPDGIDGPLG 459
EP G+ GP+G
Sbjct: 495 GEPGGV-GPIG 504
Score = 33.9 bits (76), Expect = 0.42
Identities = 112/467 (23%), Positives = 153/467 (32%), Gaps = 74/467 (15%)
Query: 29 GKAHDEGFSPQGPGQE-----CGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCP 83
G A GF P PG + G RG P+ G P P G + P G P
Sbjct: 360 GPAGGPGF-PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA--GASGNPGTDGIP 416
Query: 84 AQEGT-----VAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVD 138
+G+ +A G GP+ P G+ LG G Q G +P +
Sbjct: 417 GAKGSAGAPGIAGAPGFPGPR-GPPGPQGATGPLGPKG--------QTG------EPGIA 461
Query: 139 G--GGHGEQQGQCPGCPTGHLHPARPLNRRP---------PGRPESQEAEVGTESCQEQD 187
G G G + P P G PA +R P P + G QD
Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 521
Query: 188 AGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL 247
G+ G + G+R + A+ G + A+ G +PG P
Sbjct: 522 -GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR----GLTGRPGDAGPQGKVG 576
Query: 248 PSH-PGHHGIARHPHQEDGGIQWERGH--AQRVDGQAGAIQAVHRAVREVAVIPILVADR 304
PS PG G P G Q RG G GA +A + +P R
Sbjct: 577 PSGAPGEDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKG--LPGAPGLR 629
Query: 305 IVP----HSGSWVSPTESCQHVPEEAGEGFP-QSALEALAGHHVDDGVDAAVDVGKGDTQ 359
+P +G+ P E +G P S + L G G+G
Sbjct: 630 GLPGKDGETGA-AGPPGPAGPAGERGEQGAPGPSGFQGLPG--------PPGPPGEGGKP 680
Query: 360 GVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGP 419
G Q + + G PG GP G + A G G + + +G AG P
Sbjct: 681 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 740
Query: 420 -AKGPVVMLYNGREQDGQRQAGE-----EVGYRQVEEPDGIDGPLGL 460
A+GP + E+ AG +VG + E G DG GL
Sbjct: 741 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 787
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 48.1 bits (113), Expect = 2e-05
Identities = 124/494 (25%), Positives = 160/494 (32%), Gaps = 106/494 (21%)
Query: 29 GKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHH-NGCAQRPAASGCPAQEG 87
G + GF PG+ G G P+ + G P P +G A P A G P +G
Sbjct: 627 GPRGERGF----PGER-GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG 681
Query: 88 TV----AAGH----------GHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLV 133
AAG G +GP+ A K DG + G G EV
Sbjct: 682 MPGERGAAGIAGPKGDRGDVGEKGPEGAPGK-DGGRGLTGPIGPPGPAGANGEKGEVGPP 740
Query: 134 QPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGT--ESCQEQDAGIH 191
PA G G PG G P P P + Q G E+ Q+ DAG
Sbjct: 741 GPAGSAGARG-----APG-ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 794
Query: 192 GQQDDGG----QRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL 247
G Q G Q PT P + G Q T G+V PG P
Sbjct: 795 GPQGPSGAPGPQGPTG--VTGPKGARG---AQGPPGATGFPGAAGRVGPPGSNGNPGPPG 849
Query: 248 PSHP-------------GHHGIARHPH-QEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE 293
P P G G A P Q G E+G DG +GA
Sbjct: 850 PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD-DGPSGAEG-------- 900
Query: 294 VAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGE-GFPQSALEALAGHHVDDGVDAAVD 352
P ++ +P + GE GFP L G + G
Sbjct: 901 -------------PPGPQGLAGQRGIVGLPGQRGERGFP-----GLPGPSGEPG------ 936
Query: 353 VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEG- 411
QG G PG GP + P G ++ + GADG +D V+ D G
Sbjct: 937 -----KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE 991
Query: 412 ----GQDAAGGPAKGPVVMLYNGREQDGQRQAGEE--------VGYRQVEEPDGIDGPLG 459
G A GP P G++ D + +AG + G R ++ P G G G
Sbjct: 992 TGAVGAPGAPGPPGSPGPAGPTGKQGD-RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1050
Query: 460 LECRHPDHQGIAQH 473
E P +G+ H
Sbjct: 1051 -EAGEPGERGLKGH 1063
Score = 38.9 bits (89), Expect = 0.013
Identities = 109/446 (24%), Positives = 143/446 (32%), Gaps = 75/446 (16%)
Query: 40 GPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAG--HGHQG 97
GP G RG + P G P P G P A G + G A G QG
Sbjct: 267 GPAGAAGARGNDGQPGP---AGPPGPVGPA--GGPGFPGAPGAKGEAGPTGARGPEGAQG 321
Query: 98 PQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHL 157
P+ P GS GA G PG + + P G PG P G
Sbjct: 322 PRGEPGTP-GSPGPAGASG--------NPGTDGI---PGAKGSAGAPGIAGAPGFP-GPR 368
Query: 158 HPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGH 217
P P P P+ Q E G AG G+Q G+ G
Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGI-------AGFKGEQGPKGE-------------PGPAG 408
Query: 218 CQDGQRQTAQQIRHGQVEQPGGTHP--PAGHLPSHPGHHGIARHPHQEDG-----GIQWE 270
Q ++ + G +PGG P P G + PG+ G +DG G E
Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA-PGNRGFPG----QDGLAGPKGAPGE 463
Query: 271 RGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESC--QHVPEEAGE 328
RG + + G GA R P L R + P P E G
Sbjct: 464 RGPSG-LAGPKGANGDPGRPGE-----PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 517
Query: 329 GFP--------QSALEALAGHHVDDGVDA-AVDVGKGDTQGVQLIQQQEGDPGQAGPSEV 379
P Q + G +G A + G G++ + ++G+ G AGP
Sbjct: 518 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577
Query: 380 LAPDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGRE----Q 433
P G + +Q A G G G G E + G G A P ++ G +
Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637
Query: 434 DGQRQAGEEVGYRQVEEPDGIDGPLG 459
G A G R + G DGP G
Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKG 663
Score = 35.8 bits (81), Expect = 0.11
Identities = 36/136 (26%), Positives = 48/136 (35%), Gaps = 15/136 (11%)
Query: 325 EAGEGFPQS-ALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPD 383
+ GFP + L + GH G+D A G+ GV+ G+ G GP
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAK--GEAGAPGVKGESGSPGENGSPGPMGPRGLP 260
Query: 384 GFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEV 443
G + + GA G + D + G GPA GP G A E
Sbjct: 261 GERGRTGPAGAAGARGNDG----QPGPAGPPGPVGPAGGPGF--------PGAPGAKGEA 308
Query: 444 GYRQVEEPDGIDGPLG 459
G P+G GP G
Sbjct: 309 GPTGARGPEGAQGPRG 324
Score = 33.9 bits (76), Expect = 0.42
Identities = 107/431 (24%), Positives = 134/431 (31%), Gaps = 59/431 (13%)
Query: 38 PQGPGQECGVRGRHSEHQPQQVVGCPA-DKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQ 96
PQGP E G RG + + G D +P G P G P G
Sbjct: 55 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL-------- 106
Query: 97 GPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH 156
G A + G G V+ + P PA G G Q PG P G
Sbjct: 107 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN--PGEP-GE 163
Query: 157 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNG 216
+ P+ R P P + + G E+ + AG G G R P G
Sbjct: 164 PGVSGPMGPRGPPGPPGKPGDDG-EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222
Query: 217 HCQ-DGQRQTAQQIR-HGQVEQPG--GTHPPAGH--LPSHPGHHGIARHPHQEDGGIQWE 270
+ DG + A G+ PG G+ P G LP G G A G
Sbjct: 223 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA--------GAAGA 274
Query: 271 RGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGF 330
RG+ DGQ G P + P G + G
Sbjct: 275 RGN----DGQPG---------------PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG 315
Query: 331 PQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQK 390
P+ A A G T G+ + G PG AG P G Q
Sbjct: 316 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 375
Query: 391 AVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQV 448
A G G GQ + G+ + E G GPA GP Q AGEE
Sbjct: 376 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA-GP---------QGAPGPAGEEGKRGAR 425
Query: 449 EEPDGIDGPLG 459
EP G+ GP+G
Sbjct: 426 GEPGGV-GPIG 435
Score = 33.9 bits (76), Expect = 0.42
Identities = 112/467 (23%), Positives = 153/467 (32%), Gaps = 74/467 (15%)
Query: 29 GKAHDEGFSPQGPGQE-----CGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCP 83
G A GF P PG + G RG P+ G P P G + P G P
Sbjct: 291 GPAGGPGF-PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA--GASGNPGTDGIP 347
Query: 84 AQEGT-----VAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVD 138
+G+ +A G GP+ P G+ LG G Q G +P +
Sbjct: 348 GAKGSAGAPGIAGAPGFPGPR-GPPGPQGATGPLGPKG--------QTG------EPGIA 392
Query: 139 G--GGHGEQQGQCPGCPTGHLHPARPLNRRP---------PGRPESQEAEVGTESCQEQD 187
G G G + P P G PA +R P P + G QD
Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452
Query: 188 AGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL 247
G+ G + G+R + A+ G + A+ G +PG P
Sbjct: 453 -GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR----GLTGRPGDAGPQGKVG 507
Query: 248 PSH-PGHHGIARHPHQEDGGIQWERGH--AQRVDGQAGAIQAVHRAVREVAVIPILVADR 304
PS PG G P G Q RG G GA +A + +P R
Sbjct: 508 PSGAPGEDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKG--LPGAPGLR 560
Query: 305 IVP----HSGSWVSPTESCQHVPEEAGEGFP-QSALEALAGHHVDDGVDAAVDVGKGDTQ 359
+P +G+ P E +G P S + L G G+G
Sbjct: 561 GLPGKDGETGA-AGPPGPAGPAGERGEQGAPGPSGFQGLPG--------PPGPPGEGGKP 611
Query: 360 GVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGP 419
G Q + + G PG GP G + A G G + + +G AG P
Sbjct: 612 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 671
Query: 420 -AKGPVVMLYNGREQDGQRQAGE-----EVGYRQVEEPDGIDGPLGL 460
A+GP + E+ AG +VG + E G DG GL
Sbjct: 672 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718
Score = 29.6 bits (65), Expect = 8.0
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 355 KGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQD 414
KG+ ++ I +G PG GP+ P G + + GA G + +D + G
Sbjct: 37 KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 96
Query: 415 AAGGPAKGPVVMLYNGREQDGQRQAG--EEVGYRQVEEPDGIDGPLG 459
G P GP + G Q G E+ G Q+ G GP+G
Sbjct: 97 PPGPP--GPPGL---GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 47.8 bits (112), Expect = 3e-05
Identities = 111/465 (23%), Positives = 159/465 (34%), Gaps = 83/465 (17%)
Query: 28 EGKAHDEGFSPQ-GPGQECGVRGRHSEHQPQQVVGCP----------ADKKPHHNGCAQR 76
+G+ + G Q GP + G+ GR PQ G AD +P G A
Sbjct: 1256 KGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGN 1315
Query: 77 PAASGCPAQEGTVA-----AGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVL 131
P G P +G+ G +GP+ K +P +++G G + PG
Sbjct: 1316 PGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG---- 1371
Query: 132 LVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIH 191
P+ G G P P G P + R E G + G+
Sbjct: 1372 ---PSGPPGPRGPLGDPGPRGPPG--LPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLP 1426
Query: 192 GQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPG--GTHPPAGHLPS 249
G G + PV G + G++ ++ G QPG G P G P
Sbjct: 1427 GLPGSPGPQ-------GPVGPPG----KKGEKGDSEDGAPGLPGQPGSPGEQGPRGP-PG 1474
Query: 250 HPGHHGIARHPHQ-EDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPH 308
G G P + G + ERG G AG+ R + VA P P
Sbjct: 1475 AIGPKGDRGFPGPLGEAGEKGERG----PPGPAGS-----RGLPGVAGRPGAKGPEGPP- 1524
Query: 309 SGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQE 368
PT E G P A+AG + G DVG +G +Q +
Sbjct: 1525 -----GPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG-----DVGPAGPRGATGVQGER 1574
Query: 369 GDPGQAGPSEVLAPDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVM 426
G PG P + P G + +G G G D+G E+ + G+ GP GP
Sbjct: 1575 GPPGLVLPGDP-GPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV-GP--- 1629
Query: 427 LYNGREQDGQ-RQAGEE-----------VGYRQVEEPDGIDGPLG 459
R +DG+ + G+E G R + G+ GP+G
Sbjct: 1630 ----RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVG 1670
Score = 41.6 bits (96), Expect = 0.002
Identities = 112/473 (23%), Positives = 146/473 (30%), Gaps = 70/473 (14%)
Query: 38 PQGPGQECGVRGRHSEH-QPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQ 96
P+G E G RG E P QV+G P G P SG P G + G +
Sbjct: 1333 PRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKG---DPGPSGPPGPRGPLG-DPGPR 1388
Query: 97 GP-------QEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG--------GG 141
GP + K G G G + +PG L P G G
Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPG--EPGLPGLPGSPGPQGPVGPPGKKGE 1446
Query: 142 HGEQQGQCPGCPTGHLHPARPLNRRPPGR--PESQEAEVGTESCQEQDAGIHGQQDDGGQ 199
G+ + PG P P R PPG P+ G + + G G G
Sbjct: 1447 KGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG-EAGEKGERGPPGPAGS 1505
Query: 200 RPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHG---- 255
R RP A G RQ G+ +PG PA P+ G G
Sbjct: 1506 RGLPGVAGRPGAKGPEGPPGPTGRQ-------GEKGEPGRPGDPAVVGPAVAGPKGEKGD 1558
Query: 256 IARHPHQEDGGIQWERGHAQRV----------DGQAGAIQAVHRAVREV-AVIPILVADR 304
+ + G+Q ERG V G G I RA + P D
Sbjct: 1559 VGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDP 1618
Query: 305 IVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDV----------- 353
P V P V E+ EG P L G + G+ A V
Sbjct: 1619 GRPGPPGPVGPRGRDGEVGEKGDEGPPGDP--GLPGKAGERGLRGAPGVRGPVGEKGDQG 1676
Query: 354 -----GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQ 408
G+ + G + G+PG GP L G ++K D GQE G
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRG----- 1731
Query: 409 DEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLE 461
+G G P + + G G + P G+DG GL+
Sbjct: 1732 PKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784
Score = 38.5 bits (88), Expect = 0.017
Identities = 116/475 (24%), Positives = 160/475 (33%), Gaps = 64/475 (13%)
Query: 28 EGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKK--PHHNGCAQRPAASGCPAQ 85
+G EG P G E G++G + PQ G ++ P +G A P G P
Sbjct: 1987 QGPPGKEG--PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044
Query: 86 EGTVAAGHGHQGP--QEAKKKPDGSHRILGAGGAAVVHHTL----QPGWEVLLVQPAVDG 139
G A G G G + ++ G G G + T PG +V + +P G
Sbjct: 2045 PGR-AGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEP---G 2100
Query: 140 GGHGEQQGQCPGCPTGHLHPARPLNRRPPGRP-----ESQEAEVGTESCQEQDAGIHGQQ 194
G +QG PG P ++ P G + E G Q+ + G+ G++
Sbjct: 2101 PGLSGEQGP-PGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG-QDGNPGLPGER 2158
Query: 195 DDGGQ--RPTAHCTIRPVASTGNGHCQDGQR-------QTAQQIRHGQVEQPGGTHPP-- 243
G +P P G GH G Q G +PG T PP
Sbjct: 2159 GMAGPEGKPGLQGPRGPPGPVG-GHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGR 2217
Query: 244 -------AGHLPSHPGHHGIARHPHQEDGGIQWERGH-----------AQRVDGQAGAIQ 285
A LP PG G+ Q G+ + G A DG G+
Sbjct: 2218 GLTGPTGAVGLPGPPGPSGLVGP--QGSPGLPGQVGETGKPGAPGRDGASGKDGDRGS-- 2273
Query: 286 AVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGE-GFPQSALEALAGHHVD 344
V +P V + P G +P ++ +P GE G P L G
Sbjct: 2274 ---PGVPGSPGLPGPVGPKGEP--GPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGA 2328
Query: 345 DGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGV 404
G D + +G+ +G + GDPG+ G P GFK VG G
Sbjct: 2329 KG-DRGLPGPRGE-KGEAGRAGEPGDPGEDGQKGAPGPKGFK-GDPGVGVPGSPGPPGPP 2385
Query: 405 HVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
V+ D G G P R + GQ E G +GI GPLG
Sbjct: 2386 GVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440
Score = 32.7 bits (73), Expect = 0.94
Identities = 104/453 (22%), Positives = 139/453 (30%), Gaps = 100/453 (22%)
Query: 39 QGPGQECGVRGRHSEHQPQQVVGCPADKKPHH-NGCAQRPAASGCPAQEGTVAAGHGHQG 97
QGP G G H + P G P +G P +G P G G G
Sbjct: 2170 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPP--------GRGLTG 2221
Query: 98 PQEAK--KKPDGSHRILGAGGA----AVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPG 151
P A P G ++G G+ V T +PG P DG + PG
Sbjct: 2222 PTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPG------APGRDGASGKDGDRGSPG 2275
Query: 152 CP--TGHLHPARPLNRRPP------------------GRPESQEAEVGTESCQEQDAGIH 191
P G P P P G P ++ E + D G+
Sbjct: 2276 VPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLP 2335
Query: 192 GQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGH----L 247
G + + G+ A P G G + G PG PP L
Sbjct: 2336 GPRGEKGEAGRAGEPGDPGEDGQKG--APGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL 2393
Query: 248 PSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVP 307
P PG G+ P Q G + E G G +G RE P+
Sbjct: 2394 PGLPGAPGVVGFPGQT--GPRGEMGQP----GPSGERGLAGPPGREGIPGPL-------- 2439
Query: 308 HSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQ 367
P G P A L G D GV G+ G I+ +
Sbjct: 2440 -------------GPPGPPGSVGPPGA-SGLKGDKGDPGVGLPGPRGERGEPG---IRGE 2482
Query: 368 EGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAG-VHVEQDEGGQDAAGGPAKGPVVM 426
+G PGQ GP + P G + ++ G++ D G ++ D+G GP
Sbjct: 2483 DGRPGQEGPRGLTGPPGSRGER-------GEKGDVGSAGLKGDKGDSAVILGP------- 2528
Query: 427 LYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
G R A ++G R DG GP G
Sbjct: 2529 -------PGPRGAKGDMGERGPRGLDGDKGPRG 2554
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 45.1 bits (105), Expect = 2e-04
Identities = 59/300 (19%), Positives = 97/300 (32%), Gaps = 51/300 (17%)
Query: 2 ANQQQNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVG 61
+ +Q+ S+GS+ +HG + S G S Q P RGRH Q
Sbjct: 968 SRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS---RGRHGSGSGQS--- 1021
Query: 62 CPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVH 121
+ P+ +G SG + G +G GH ++ G G G++ H
Sbjct: 1022 --SSYGPYRSG-------SGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH 1072
Query: 122 HTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTE 181
+ G HG GQ C + + G SQ + G +
Sbjct: 1073 SSTH--------------GQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 1118
Query: 182 SCQEQDAGIHGQQDDGGQRPTAHCTIRPVA---------------STGNGHCQDGQRQTA 226
+ HGQ+ G ++ ++ + S+G GH + Q++
Sbjct: 1119 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1178
Query: 227 QQIRHGQ-------VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 279
+HG Q G + H G + H Q G + GH ++ G
Sbjct: 1179 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 1238
Score = 41.2 bits (95), Expect = 0.003
Identities = 54/240 (22%), Positives = 72/240 (30%), Gaps = 36/240 (15%)
Query: 27 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 86
S G H E S Q G G G S H G + C Q A SG +
Sbjct: 581 SSGLGHQESRSGQSSGY--GQHGSSSGHSSTH--GQHGSTSGQSSSCGQHGATSGQSSSH 636
Query: 87 GTVAAG------HGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVL-----LVQP 135
G +G +G QG + G H ++ H GW V
Sbjct: 637 GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSG 696
Query: 136 AVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQD 195
G GH GQ G + R G Q + + +GQ
Sbjct: 697 QSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG 756
Query: 196 DGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHG 255
G + S+G+G G + ++RHG +GH SH G HG
Sbjct: 757 SGSHQ-----------SSGHGRQGSGSGHSPSRVRHGS---------SSGHSSSH-GQHG 795
Score = 37.4 bits (85), Expect = 0.038
Identities = 61/292 (20%), Positives = 90/292 (30%), Gaps = 51/292 (17%)
Query: 10 STGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCP------ 63
S+GS+ +HG + S G S Q P RGRH Q P
Sbjct: 2386 SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS---RGRHGSGSGQSSSYSPYGSGSG 2442
Query: 64 --ADKKP------HHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG 115
+ + P H +G R + SG ++G+G G G H
Sbjct: 2443 WSSSRGPYESGSGHSSGLGHRESRSG-------QSSGYGQHGSSSGHSSTHGQHGSTSGQ 2495
Query: 116 GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQ- 174
++ H G + G HG Q G R+ G +S
Sbjct: 2496 SSSCGQHGASSG-------QSSSHGQHGSGSSQSSG-----------YGRQGSGSGQSPG 2537
Query: 175 EAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ- 233
+ G+ S Q G HG H + S+G GH + Q++ +HG
Sbjct: 2538 HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS-GLGESSGFGHHESSSGQSSSYSQHGSG 2596
Query: 234 ------VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 279
Q G + H G + H Q G + GH ++ G
Sbjct: 2597 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 2648
Score = 37.0 bits (84), Expect = 0.050
Identities = 60/262 (22%), Positives = 83/262 (31%), Gaps = 41/262 (15%)
Query: 27 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 86
S G H E S Q G G G S H G + C Q A+SG +
Sbjct: 1047 SSGLGHRESRSGQSSGY--GQHGSSSGHSSTH--GQHGSTSGQSSSCGQHGASSGQSSSH 1102
Query: 87 G------TVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 140
G + ++G+G QG + G + H G + G
Sbjct: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG-------RSSSSG 1155
Query: 141 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 200
HG G+ G GH S ++ G+ S G HG + R
Sbjct: 1156 QHGSGLGESSG--FGH--------HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 1205
Query: 201 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPA--------GHLPSHPG 252
H + +S+ G G RQ++ R G G H P+ GH SH G
Sbjct: 1206 GERHGS-SSGSSSHYGQHGSGSRQSSGHGRQGS----GSGHSPSRGRHGSGLGHSSSH-G 1259
Query: 253 HHGIARHPHQEDGGIQWERGHA 274
HG G + GH+
Sbjct: 1260 QHGSGSGRSSSRGPYESRSGHS 1281
Score = 36.6 bits (83), Expect = 0.065
Identities = 60/262 (22%), Positives = 83/262 (31%), Gaps = 41/262 (15%)
Query: 27 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 86
S G H E S Q G G G S H G + C Q A+SG +
Sbjct: 1987 SSGLGHRESRSGQSSGY--GQHGSSSGHSSTH--GQHGSASGQSSSCGQHGASSGQSSSH 2042
Query: 87 G------TVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 140
G + ++G+G QG + G + H G + G
Sbjct: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG-------RSSSSG 2095
Query: 141 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 200
HG G+ G GH S ++ G+ S G HG + R
Sbjct: 2096 QHGPGLGESSG--FGH--------HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2145
Query: 201 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPP--------AGHLPSHPG 252
H + +S+ G G RQ++ R G G H P +GH SH G
Sbjct: 2146 GERHGS-SSGSSSRYGQHGSGSRQSSGHGRQGS----GSGHSPSRGRHGSGSGHSSSH-G 2199
Query: 253 HHGIARHPHQEDGGIQWERGHA 274
HG G + GH+
Sbjct: 2200 QHGSGSGRSSSRGPYESRSGHS 2221
Score = 35.8 bits (81), Expect = 0.11
Identities = 63/272 (23%), Positives = 88/272 (32%), Gaps = 35/272 (12%)
Query: 13 SNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNG 72
S+R E G ++ S G H E S Q G G G S H G +
Sbjct: 1505 SSRGPYESG--SSHSSGLGHRESRSGQSSGY--GQHGSSSGHSSTH--GQHGSTSGQSSS 1558
Query: 73 CAQRPAASGCPAQEG------TVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQP 126
C Q A+SG + G + ++G+G QG + G + H
Sbjct: 1559 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1618
Query: 127 GWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQ 186
G + G HG G+ G GH S ++ G+ S
Sbjct: 1619 G-------RSSSSGQHGSGLGESSG--FGH--------HESSSGQSSSYSQHGSGSGHSS 1661
Query: 187 DAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRH----GQVEQPGGTHP 242
G HG + R H + +S+ G G RQ++ R GQ G
Sbjct: 1662 GYGQHGSRSGQSSRGERHGS-SSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGS 1720
Query: 243 PAGHLPSHPGHHGIARHPHQEDGGIQWERGHA 274
GH SH G HG G + GH+
Sbjct: 1721 GLGHSSSH-GQHGSGSGRSSSRGPYESRSGHS 1751
Score = 35.4 bits (80), Expect = 0.15
Identities = 63/299 (21%), Positives = 95/299 (31%), Gaps = 55/299 (18%)
Query: 5 QQNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVV---- 60
+Q+ S+GS+ +HG + S G S Q P RGRH Q
Sbjct: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS---RGRHGSGSGQSSSYGPY 1967
Query: 61 ----GCPADKKP------HHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHR 110
G + + P H +G R + SG ++G+G G G H
Sbjct: 1968 GSGSGWSSSRGPYESGSGHSSGLGHRESRSG-------QSSGYGQHGSSSGHSSTHGQHG 2020
Query: 111 ILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGR 170
++ H G + G HG Q G R+ G
Sbjct: 2021 SASGQSSSCGQHGASSG-------QSSSHGQHGSGSSQSSG-----------YGRQGSGS 2062
Query: 171 PESQ-EAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRP--VASTGNGHCQDGQRQTAQ 227
+S + G+ S Q G HG G R ++ P S+G GH + Q++
Sbjct: 2063 GQSPGHGQRGSGSRQSPSYGRHG---SGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSS 2119
Query: 228 QIRHGQ-------VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 279
+HG Q G + H G + Q G + GH ++ G
Sbjct: 2120 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178
Score = 35.0 bits (79), Expect = 0.19
Identities = 53/251 (21%), Positives = 77/251 (30%), Gaps = 58/251 (23%)
Query: 6 QNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPAD 65
Q+ S+G + +HG ++ S G S Q PG G RG S P
Sbjct: 2031 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH--GQRGSGSRQSPSY------- 2081
Query: 66 KKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQ 125
H + R ++SG ++G GH E+ S+ G+G +
Sbjct: 2082 --GRHGSGSGRSSSSGQHGPGLGESSGFGH---HESSSGQSSSYSQHGSGSGHSSGY--- 2133
Query: 126 PGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQE 185
G HG + GQ G H G + G
Sbjct: 2134 --------------GQHGSRSGQ---SSRGERH----------GSSSGSSSRYGQHGSGS 2166
Query: 186 QDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAG 245
+ + HG+Q G + H R +G+GH HGQ G G
Sbjct: 2167 RQSSGHGRQGSG----SGHSPSRGRHGSGSGHSSS----------HGQHGSGSGRSSSRG 2212
Query: 246 HLPSHPGHHGI 256
S GH +
Sbjct: 2213 PYESRSGHSSV 2223
Score = 35.0 bits (79), Expect = 0.19
Identities = 59/258 (22%), Positives = 81/258 (31%), Gaps = 33/258 (12%)
Query: 27 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 86
S G H E S Q G G G S H G + C Q A+SG +
Sbjct: 2457 SSGLGHRESRSGQSSGY--GQHGSSSGHSSTH--GQHGSTSGQSSSCGQHGASSGQSSSH 2512
Query: 87 G------TVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 140
G + ++G+G QG + G + H G + G
Sbjct: 2513 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG-------RSSSSG 2565
Query: 141 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 200
HG G+ G GH S ++ G+ S G HG + R
Sbjct: 2566 QHGSGLGESSG--FGH--------HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2615
Query: 201 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRH----GQVEQPGGTHPPAGHLPSHPGHHGI 256
H + +S+ G G RQ++ R GQ G GH SH G HG
Sbjct: 2616 GERHGS-SSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH-GQHGS 2673
Query: 257 ARHPHQEDGGIQWERGHA 274
G + GH+
Sbjct: 2674 GSGRSSSRGPYESRLGHS 2691
Score = 33.9 bits (76), Expect = 0.42
Identities = 55/256 (21%), Positives = 75/256 (29%), Gaps = 48/256 (18%)
Query: 32 HDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA 91
H G G C H E Q G + G +Q +ASG + +G +
Sbjct: 787 HSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGS 846
Query: 92 GHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPG 151
G G G +A H A G HG GQ PG
Sbjct: 847 TSGQSSSSGQHDSSSGQSSSYGQHESASHH--------------ASGRGRHGSGSGQSPG 892
Query: 152 CPTGHLHPARPLNRRPPGRPESQE-AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPV 210
+R G +S G+ S + +G HG GQ
Sbjct: 893 -----------HGQRGSGSGQSPSYGRHGSGSGRSSSSGRHG--SGSGQ----------- 928
Query: 211 ASTGNGHCQDGQRQTAQQIRHG-------QVEQPGGTHPPAGHLPSHPGHHGIARHPHQE 263
S+G GH + Q++ +HG EQ G + H G + Q
Sbjct: 929 -SSGFGH-KSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQH 986
Query: 264 DGGIQWERGHAQRVDG 279
G + GH Q G
Sbjct: 987 GSGSRQSLGHGQHGSG 1002
Score = 33.9 bits (76), Expect = 0.42
Identities = 53/251 (21%), Positives = 76/251 (30%), Gaps = 58/251 (23%)
Query: 6 QNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPAD 65
Q+ S+G + +HG ++ S G S Q PG G RG S P
Sbjct: 1091 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH--GQRGSGSRQSPSY------- 1141
Query: 66 KKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQ 125
H + R ++SG ++G GH E+ S+ G+G +
Sbjct: 1142 --GRHGSGSGRSSSSGQHGSGLGESSGFGH---HESSSGQSSSYSQHGSGSGHSSGY--- 1193
Query: 126 PGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQE 185
G HG + GQ G H G + G
Sbjct: 1194 --------------GQHGSRSGQ---SSRGERH----------GSSSGSSSHYGQHGSGS 1226
Query: 186 QDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAG 245
+ + HG+Q G + H R +G GH HGQ G G
Sbjct: 1227 RQSSGHGRQGSG----SGHSPSRGRHGSGLGHSSS----------HGQHGSGSGRSSSRG 1272
Query: 246 HLPSHPGHHGI 256
S GH +
Sbjct: 1273 PYESRSGHSSV 1283
Score = 33.5 bits (75), Expect = 0.55
Identities = 55/252 (21%), Positives = 78/252 (30%), Gaps = 60/252 (23%)
Query: 6 QNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPAD 65
Q+ S+G + +HG ++ S G S Q PG G RG S P
Sbjct: 1561 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH--GQRGSGSRQSPSY------- 1611
Query: 66 KKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQ 125
H + R ++SG ++G GH E+ S+ G+G +
Sbjct: 1612 --GRHGSGSGRSSSSGQHGSGLGESSGFGH---HESSSGQSSSYSQHGSGSGHSSGY--- 1663
Query: 126 PGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQE 185
G HG + GQ G H G + G
Sbjct: 1664 --------------GQHGSRSGQ---SSRGERH----------GSSSRSSSRYGQHGSGS 1696
Query: 186 QDAGIHGQQDDG-GQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPA 244
+ + HG+Q G GQ P+ R +G GH HGQ G
Sbjct: 1697 RQSSGHGRQGSGSGQSPS-----RGRHGSGLGHSSS----------HGQHGSGSGRSSSR 1741
Query: 245 GHLPSHPGHHGI 256
G S GH +
Sbjct: 1742 GPYESRSGHSSV 1753
Score = 33.1 bits (74), Expect = 0.72
Identities = 55/252 (21%), Positives = 78/252 (30%), Gaps = 60/252 (23%)
Query: 6 QNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPAD 65
Q+ S+G + +HG ++ S G S Q PG G RG S P
Sbjct: 2501 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGH--GQRGSGSRQSPSY------- 2551
Query: 66 KKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQ 125
H + R ++SG ++G GH E+ S+ G+G +
Sbjct: 2552 --GRHGSGSGRSSSSGQHGSGLGESSGFGH---HESSSGQSSSYSQHGSGSGHSSGY--- 2603
Query: 126 PGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQE 185
G HG + GQ G H G + G
Sbjct: 2604 --------------GQHGSRSGQ---SSRGERH----------GSSSGSSSHYGQHGSGS 2636
Query: 186 QDAGIHGQQDDG-GQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPA 244
+ + HG+Q G GQ P+ R +G GH HGQ G
Sbjct: 2637 RQSSGHGRQGSGSGQSPS-----RGRHGSGLGHSSS----------HGQHGSGSGRSSSR 2681
Query: 245 GHLPSHPGHHGI 256
G S GH +
Sbjct: 2682 GPYESRLGHSSV 2693
Score = 31.6 bits (70), Expect = 2.1
Identities = 33/144 (22%), Positives = 47/144 (32%), Gaps = 8/144 (5%)
Query: 140 GGHGEQQGQCPGCPT---GHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDD 196
G HG GQ T G + + S ++ G+ S G HG +
Sbjct: 206 GQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSG 265
Query: 197 GGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGI 256
R H + +S+ H G RQ+ R G + +H G H HG
Sbjct: 266 QSSRGERHRSSSGSSSSYGQH-GSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHG- 323
Query: 257 ARHPHQEDGGIQWERGHAQRVDGQ 280
H + RGH + GQ
Sbjct: 324 ---QHGSGSSYSYSRGHYESGSGQ 344
Score = 30.8 bits (68), Expect = 3.6
Identities = 62/310 (20%), Positives = 99/310 (31%), Gaps = 70/310 (22%)
Query: 11 TGSNRREEEHGIEAAVSEGKAHDEGFSPQ---------GPGQECGV--RGRHSEHQPQQ- 58
+G + +HG ++ S + H E S Q G GQ G G S H Q
Sbjct: 316 SGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQG 375
Query: 59 ----VVGCPADKKPH------------HNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAK 102
G + H H ++ + G + + GHG +G +
Sbjct: 376 QHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQ 435
Query: 103 KKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGE----------QQGQCPGC 152
G H ++ + G+ G GH E Q G G
Sbjct: 436 SPSSGQHGTGFGRSSSSGPYVSGSGYS--------SGFGHHESSSEHSSGYTQHGSGSGH 487
Query: 153 PTGH-LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVA 211
+GH H +R R E Q + G+ S +GQ G ++ H +
Sbjct: 488 SSGHGQHGSR---SGQSSRGERQGSSAGSSSS-------YGQHGSGSRQSLGH------S 531
Query: 212 STGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWER 271
G+G GQ + + RH + ++ P G+ G P++ G
Sbjct: 532 RHGSG---SGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRG----PYESGSGHSSGL 584
Query: 272 GHAQRVDGQA 281
GH + GQ+
Sbjct: 585 GHQESRSGQS 594
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 43.9 bits (102), Expect = 4e-04
Identities = 112/523 (21%), Positives = 151/523 (28%), Gaps = 74/523 (14%)
Query: 10 STGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVR--GRHSEHQPQQVVGCPADKK 67
ST R+ HG G G S G + G R GR Q+ A
Sbjct: 1305 STVRRRQGTTHG-----QRGDTTRHGHSGHGQSTQTGSRTSGR------QRFSHSDATDS 1353
Query: 68 PHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHR---ILGAGGAAVVHHTL 124
H+G + RP + QE T H G Q + + R G G A H
Sbjct: 1354 EVHSGVSHRPHS-----QEQT----HSQAGSQHGESESTVHERHETTYGQTGEATGHGHS 1404
Query: 125 QPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQ 184
G G G + +G H RP+SQE G Q
Sbjct: 1405 GHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSH-----------RPQSQEQTHGQAGSQ 1453
Query: 185 EQDAG---------IHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE 235
++G HGQ D T H ST G G+R +
Sbjct: 1454 HGESGSTVHGRHGTTHGQTGD----TTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEV 1509
Query: 236 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWER---GHAQRVD-------GQAGAIQ 285
GG+H +GH HG + H E I +R H Q D G Q
Sbjct: 1510 HSGGSHTHSGHT------HGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQ 1563
Query: 286 AVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDD 345
R D V HSG P S +H +AG + H
Sbjct: 1564 TGSRTTGRQRTSHSESTDSEV-HSGGSHRP-HSREHTYGQAGSQHEEPEFTVHERHGTTH 1621
Query: 346 GV------DAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQE 399
G + G+ +G + +Q ++ SEV + H G G Q
Sbjct: 1622 GQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQH 1681
Query: 400 QDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEE-VGYRQVEEPDGIDGPL 458
+ V + G G + Q G R G G+ + + +G G
Sbjct: 1682 GQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVS 1741
Query: 459 GLECRHPDHQGIAQHSHQEDDCKDDQGQDVWNTQRVRSFIHRG 501
H Q +QH E + G T H G
Sbjct: 1742 HTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSG 1784
Score = 40.4 bits (93), Expect = 0.005
Identities = 85/387 (21%), Positives = 119/387 (30%), Gaps = 51/387 (13%)
Query: 142 HGEQQGQCPGCPTGHLHP---------ARPLNRRPPGRPESQEAEVGTESCQEQDAGIHG 192
HG GQ G T H H +R RR G E ++E + Q + H
Sbjct: 1767 HGTIHGQT-GDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHT 1825
Query: 193 QQDDGGQRPTA-------HCTIRPVASTGNGHCQDGQRQTAQ-------QIRHGQVEQP- 237
G Q + H T +GH Q G Q+ Q + R G E
Sbjct: 1826 HGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSD 1885
Query: 238 -----GGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWER---GHAQRVD----GQAGAIQ 285
GG+H +GH H AR H E +R H Q D G Q
Sbjct: 1886 SEVHSGGSHTHSGHT------HSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQ 1939
Query: 286 AVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDD 345
+ R ++ S VS T S H +AG +P+S H
Sbjct: 1940 TIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHS-GHTHGQAGSHYPESGSSVHERHGTTH 1998
Query: 346 GVDAAV------DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQE 399
G A G+ +G + ++ + SE + H A G G Q
Sbjct: 1999 GQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQH 2058
Query: 400 QDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEE-VGYRQVEEPDGIDGPL 458
++G V + G G + Q G R AG G+ + + + G
Sbjct: 2059 GESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVS 2118
Query: 459 GLECRHPDHQGIAQHSHQEDDCKDDQG 485
H Q +QH QG
Sbjct: 2119 HTHSGHTYGQARSQHGESGSAIHGRQG 2145
Score = 40.4 bits (93), Expect = 0.005
Identities = 65/271 (23%), Positives = 90/271 (33%), Gaps = 70/271 (25%)
Query: 20 HGIEAAV--SEGKAHDEGFSPQGPGQECGVR--GR----HSEHQPQQVVGCPADKKPHHN 71
HG + + G G S G + G R GR HSE +V ++ P H+
Sbjct: 2141 HGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEV---HSEASPTHS 2197
Query: 72 GCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVL 131
G A S Q G+ +GHG QG + H H+
Sbjct: 2198 GHTHSQAGSR-HGQSGS--SGHGRQGTTHGQTGDTTRH----------AHY--------- 2235
Query: 132 LVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIH 191
G G Q+G +R RR G ES ++EV + I
Sbjct: 2236 -------GYGQSTQRG------------SRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQ 2276
Query: 192 GQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHG-----QVEQPGGTHPPAGH 246
GQ ++P ST +G + QT RHG Q Q G A H
Sbjct: 2277 GQAGSQQRQP---------GSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASH 2327
Query: 247 LPSHPG---HHGIAR-HPHQEDGGIQWERGH 273
SH HG ++ H G +++ GH
Sbjct: 2328 FQSHSSERQRHGSSQVWKHGSYGPAEYDYGH 2358
Score = 29.6 bits (65), Expect = 8.0
Identities = 56/252 (22%), Positives = 78/252 (30%), Gaps = 39/252 (15%)
Query: 11 TGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHH 70
+G R +E K+H G E G E + + C + H
Sbjct: 191 SGGKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHE 250
Query: 71 NGCAQ-----RPAASGCPAQEGTVAAGH--------GHQGPQEAKKKPDGSHRILGAGGA 117
+ Q + S C + H G PQ A SHR G G
Sbjct: 251 SNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQ-SHRFGGQGNQ 309
Query: 118 AVVHHTLQPGWEVLLVQPAVDGG-GHG-EQQGQCPGC------PTGHLHPARPLNRRPPG 169
+Q G Q + GG GHG GQ GC P + R R G
Sbjct: 310 ---FSYIQSG-----CQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENG 361
Query: 170 RPESQEAEVGTESCQEQDAGIHG----QQDDGGQRPTAHCTIRPVASTGNGHCQ-----D 220
+P++ + T S Q G +G Q GQ C +S+ N +
Sbjct: 362 QPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGS 421
Query: 221 GQRQTAQQIRHG 232
G Q+ +HG
Sbjct: 422 GSSQSTSFEQHG 433
Score = 29.6 bits (65), Expect = 8.0
Identities = 50/234 (21%), Positives = 79/234 (33%), Gaps = 24/234 (10%)
Query: 19 EHGIEAAVS-------EGKAHDEGFSPQGPG--QECGVRGRHSEHQPQQVVGCPADKKPH 69
+HG+ + S G GF G G Q G G+H Q G +
Sbjct: 569 QHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGF-GQHESRSGQSSYGQHSSGSSQ 627
Query: 70 HNGCAQ----RPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG-GAAVVHHTL 124
+G Q + + G + + G G G + G H + G+G + H
Sbjct: 628 SSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQH-VSGSGQSSGFGQHES 686
Query: 125 QPGWEV-----LLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVG 179
+ G + G HG GQ G L + + G Q + G
Sbjct: 687 RSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFG 746
Query: 180 TE-SCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHG 232
S Q +G + GQ +++ +S +G+ Q G RQT+ +HG
Sbjct: 747 QHGSGSGQSSGFGQHESRSGQ--SSYGQHSSGSSQSSGYGQHGSRQTSGFGQHG 798
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 43.5 bits (101), Expect = 5e-04
Identities = 110/440 (25%), Positives = 138/440 (31%), Gaps = 80/440 (18%)
Query: 38 PQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHN-GCAQRPAASGCPAQEGTVAAGHGHQ 96
P GP E G G VG + N G P +G P ++G +A GHG
Sbjct: 682 PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKG-MAGGHGPD 740
Query: 97 GPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG--GGHGEQQGQCPGCPT 154
GP+ P G+ G G + PG + P G GG GE+ +
Sbjct: 741 GPK-GSPGPSGTPGDTGPPGLQGM-----PGERGIAGTPGPKGDRGGIGEKGAEGTAGND 794
Query: 155 GHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTG 214
G PL P P ++ E G G G + + G R P + G
Sbjct: 795 GARGLPGPLGPPGPAGPTGEKGEPGPRGL----VGPPGSRGNPGSRGENG----PTGAVG 846
Query: 215 NGHCQDGQRQTAQQIRHGQVEQPG--GTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERG 272
Q Q + G+ Q G G+ P G L PG HG P G++ RG
Sbjct: 847 FAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQG-LAGSPGPHGPNGVP-----GLKGGRG 900
Query: 273 HAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQ 332
G GA P S V P P AG P
Sbjct: 901 ----TQGPPGATG--------------------FPGSAGRVGP-------PGPAGAPGPA 929
Query: 333 SAL-----EALAGHHVDDGVDAAV-DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFK 386
L E G D G V D G G + G+ GQ GP P G
Sbjct: 930 GPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTT 989
Query: 387 HQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQD-------GQRQA 439
Q+ VG G ++ E G GPA P + G D G +
Sbjct: 990 GQRGIVGMPG----------QRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGS 1039
Query: 440 GEEVGYRQVEEPDGIDGPLG 459
VG E P G DG G
Sbjct: 1040 NGPVGEPGPEGPAGNDGTPG 1059
Score = 42.0 bits (97), Expect = 0.002
Identities = 101/402 (25%), Positives = 126/402 (31%), Gaps = 63/402 (15%)
Query: 39 QGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGH-GHQG 97
QGP E G +GR PQ + G P G +P A G P GH H G
Sbjct: 140 QGPRGERGPKGRPGPRGPQGIDGEP--------GVPGQPGAPGPP--------GHPSHPG 183
Query: 98 PQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH- 156
P + L L PG V V P G G+Q G P P G
Sbjct: 184 PDGLSRPFSAQMAGLDEKSGLGSQVGLMPG-SVGPVGPRGPQGLQGQQGGAGPTGPPGEP 242
Query: 157 --LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTG 214
P P+ R P P + E G E + + G G G R P
Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDG-EPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301
Query: 215 NGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGH- 273
GH + + + G + G T P P P G+ ERG
Sbjct: 302 RGH-KGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGP-------------RGMPGERGRL 347
Query: 274 -AQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQ 332
Q GQ GA + P + +P S + P GE P
Sbjct: 348 GPQGAPGQRGA--------HGMPGKPGPMGPLGIPGSSGFPGN-------PGMKGEAGPT 392
Query: 333 SAL--EALAGHHVDDGVDAAVD----VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFK 386
A E G + G V G T G + G PG +GP P G
Sbjct: 393 GARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSP 452
Query: 387 HQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGP--AKGPV 424
Q + G G GQ D GV + E G GP +GP+
Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPI 494
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 43.5 bits (101), Expect = 5e-04
Identities = 104/417 (24%), Positives = 136/417 (32%), Gaps = 81/417 (19%)
Query: 60 VGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAV 119
+G P D P G +P A G P G + G +GP P G+ + G
Sbjct: 915 IGPPGDNGPE--GMKGKPGARGLPGPRGQLGP-EGDEGPMG----PPGAPGLEG------ 961
Query: 120 VHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVG 179
QPG + +P +DG GE PG P RP P ++ +G
Sbjct: 962 -----QPGRKGFPGRPGLDGV-KGE-----PG------DPGRP-------GPVGEQGFMG 997
Query: 180 TESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGG 239
+ GI G++ D G P S G+ G G +PG
Sbjct: 998 FIGLVGEP-GIVGEKGDRGMMGPPGVP-GPKGSMGHPGMPGGM---------GTPGEPGP 1046
Query: 240 THPPAGHLPSHPGHHGIA--RHPHQEDG-----------GIQWERGHAQRVDGQAGAIQA 286
PP P PG G R P DG G +G R Q A +
Sbjct: 1047 QGPPGSRGP--PGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGER 1104
Query: 287 VHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPE----EAGEGFPQSALEALAGHH 342
H R IP G+ P E P+ GE P+ A+
Sbjct: 1105 GHLGSRGFPGIPGPSGP-----PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPG 1159
Query: 343 VDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDA 402
+ D+G T G Q + Q G+PG G S + PDG K D G
Sbjct: 1160 LPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLK-------GDRGDPGPD 1212
Query: 403 GVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
G H E+ + G GP P V G E +Q E G + G G LG
Sbjct: 1213 GEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQG--EKGRTGAKGAKGYQGQLG 1267
Score = 36.6 bits (83), Expect = 0.065
Identities = 116/460 (25%), Positives = 151/460 (32%), Gaps = 98/460 (21%)
Query: 38 PQGPGQECGVRGRHSEHQPQQVVGCP-----ADKKPH--HNGCAQRPAASGCPAQEGTVA 90
P GP E G RG PQ G P A ++ H G P SG P +G +
Sbjct: 1070 PDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKG-LP 1128
Query: 91 AGHGHQGPQE--------AKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG--G 140
G QGPQ K P G+ G G A + L P L P G G
Sbjct: 1129 GEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGP-----LGTPGEQGLIG 1183
Query: 141 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDA--------GIHG 192
GE + P G +R PG P+ + E G E +D G+ G
Sbjct: 1184 QRGEPGLEGDSGPMGP--DGLKGDRGDPG-PDGEHGEKGQEGLMGEDGPPGPPGVTGVRG 1240
Query: 193 QQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPG 252
+ G++ R A G+ Q + G++ PG PP P G
Sbjct: 1241 PEGKSGKQGEKG---RTGAKGAKGY----------QGQLGEMGVPGDPGPPG--TPGPKG 1285
Query: 253 HHGIARHPHQEDG--GIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSG 310
G + P G G Q E G A DG G IV G
Sbjct: 1286 SRG-SLGPTGAPGRMGAQGEPGLAG-YDGHKG----------------------IVGPLG 1321
Query: 311 SWVSPTESCQHVPEEAGEGFPQSALE-ALAGHHVDDGVDAAVDVGKGDTQGVQLIQQ--- 366
E + + EG P + G D G D G +GVQ ++
Sbjct: 1322 PPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG--DPGYPGQEGVQGLRGKPG 1379
Query: 367 QEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVM 426
Q+G PG GP P G K GA+G + + G Q G P VV
Sbjct: 1380 QQGQPGHPGPRGWPGPKGSK------GAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVV- 1432
Query: 427 LYNGRE-------QDGQRQAGEEVGYRQVEEPDGIDGPLG 459
GR+ DG + G + + DG GP+G
Sbjct: 1433 ---GRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMG 1469
Score = 35.4 bits (80), Expect = 0.15
Identities = 112/458 (24%), Positives = 148/458 (32%), Gaps = 109/458 (23%)
Query: 19 EHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPA 78
EHG + EG ++G P GP GVRG P+ G +K G
Sbjct: 1214 EHGEKG--QEGLMGEDG--PPGPPGVTGVRG------PEGKSGKQGEK-----GRTGAKG 1258
Query: 79 ASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVD 138
A G Q G + G GP P GS LG GA PG +P +
Sbjct: 1259 AKGYQGQLGEMGVP-GDPGPP-GTPGPKGSRGSLGPTGA--------PGRMGAQGEPGLA 1308
Query: 139 GGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGG 198
G GH PL PPG P+ ++ E G + E G G + G
Sbjct: 1309 GYD-------------GHKGIVGPLG--PPG-PKGEKGEQGEDGKAEGPPGPPGDRGPVG 1352
Query: 199 QRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIAR 258
R G+ + + + GQ QPG HP P G G A
Sbjct: 1353 DRGDR-------GEPGDPGYPGQEGVQGLRGKPGQQGQPG--HPGPRGWPGPKGSKG-AE 1402
Query: 259 HPHQEDG--GIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPT 316
P + G G RG Q + G G V R E P
Sbjct: 1403 GPKGKQGKAGAPGRRG-VQGLQGLPGPRGVVGRQGLEGIAGP------------------ 1443
Query: 317 ESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGP 376
+P G+ Q G DDG D G G + G+PG AG
Sbjct: 1444 ---DGLPGRDGQAGQQ-------GEQGDDG-----DPGPMGPAG------KRGNPGVAGL 1482
Query: 377 SEVLAPDGFKHQQKAVGADG-----GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGR 431
P GFK + G G G E G+ Q E G + G P +
Sbjct: 1483 PGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPG--SKGQPGDSGEMGFPGMA 1540
Query: 432 EQDGQRQAGEEVGYRQVEEP---------DGIDGPLGL 460
G + ++G++ ++ P +GI GPLG+
Sbjct: 1541 GLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGI 1578
Score = 33.5 bits (75), Expect = 0.55
Identities = 108/443 (24%), Positives = 146/443 (32%), Gaps = 90/443 (20%)
Query: 46 GVRGRHSEHQPQQVVGCPA-DKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKK 104
G G + P G P + +P G RP G + G G GP +
Sbjct: 940 GQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDP----GRPGPVGEQ-- 993
Query: 105 PDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG--GGHGEQQGQCPGCPTGHLHPARP 162
G +G G + + G ++ P V G G G PG P G P P
Sbjct: 994 --GFMGFIGLVGEPGI--VGEKGDRGMMGPPGVPGPKGSMGH-----PGMPGGMGTPGEP 1044
Query: 163 LNRRPPGR--PESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQD 220
+ PPG P G + D G G+Q G + RP +
Sbjct: 1045 GPQGPPGSRGPPGMRGAKGRRGPRGPD-GPAGEQGSRGLKGPPGPQGRPG--------RP 1095
Query: 221 GQRQTAQQIRH----GQVEQPGGTHPPAGH-LPSHPGHHGIARHPHQEDGGIQWERGHAQ 275
GQ+ A + H G PG + PP LP PG G Q G E G
Sbjct: 1096 GQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQG-----PQGPIGPPGEMGPK- 1149
Query: 276 RVDGQAGAIQAVHRAVREVAVIPILVADRIVPHS-GSWVSPTESC----QHVPEEAGEGF 330
G GA+ P L + + G +P E + P G+
Sbjct: 1150 ---GPPGAVGE-----------PGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSG 1195
Query: 331 PQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQK 390
P + L G D G D G+ +G + + ++G PG G + V P+G +Q
Sbjct: 1196 PMGP-DGLKGDRGDPGPD-----GEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQG 1249
Query: 391 ------AVGADGGQEQDAGVHVEQDEG--------GQDAAGGPAKGPVVMLYNGREQDGQ 436
A GA G Q Q + V D G G + GP P G+
Sbjct: 1250 EKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAP-----------GR 1298
Query: 437 RQAGEEVGYRQVEEPDGIDGPLG 459
A E G + GI GPLG
Sbjct: 1299 MGAQGEPGLAGYDGHKGIVGPLG 1321
Score = 30.4 bits (67), Expect = 4.7
Identities = 33/126 (26%), Positives = 47/126 (37%), Gaps = 11/126 (8%)
Query: 352 DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDA--------G 403
D+G G + ++ + G G GP L P+G + GA G + Q G
Sbjct: 914 DIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPG 973
Query: 404 VHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECR 463
+ + E G GP M + G G+ E G R + P G+ GP G
Sbjct: 974 LDGVKGEPGDPGRPGPVGEQGFMGFIGLV--GEPGIVGEKGDRGMMGPPGVPGPKG-SMG 1030
Query: 464 HPDHQG 469
HP G
Sbjct: 1031 HPGMPG 1036
>gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo
sapiens]
Length = 767
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/182 (28%), Positives = 69/182 (37%), Gaps = 19/182 (10%)
Query: 15 RREEEHGIEA--AVSEGKAHDEG-FSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHN 71
+ EEEHG++ +V E DEG G + C G + ++ G +
Sbjct: 46 QEEEEHGVKGVESVLEKGVLDEGVLEAWGCCRRCRHAGWNRSQPSPELAGAVIHARAPAV 105
Query: 72 GCAQRPAASGC---------PAQEGTVAAGHGHQGP-QEAKKKPDGSHRIL--GAGGAAV 119
GC QR P QE P E +KP+GS + G G AV
Sbjct: 106 GCRQRSGHLHVRLKQRLLERPCQEPLGKKYQLELPPLYERARKPEGSKNLPADGQGLRAV 165
Query: 120 VHHTLQPGWEVLLVQP---AVDGGGHGEQQGQCPGCPTGHLH-PARPLNRRPPGRPESQE 175
P W +P A + G G+ QGQ P T HL P P +PE++E
Sbjct: 166 RADAALPVWPGGPGRPGPHAPEAGAEGQHQGQWPPADTRHLRTPKWPYKVATEEKPEAEE 225
Query: 176 AE 177
AE
Sbjct: 226 AE 227
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 42.4 bits (98), Expect = 0.001
Identities = 110/443 (24%), Positives = 137/443 (30%), Gaps = 62/443 (13%)
Query: 38 PQGPGQECGVRGRHSEHQPQQVVGCPADK-KPHHNGCAQRPAASGCPAQEGTVAAGHGHQ 96
P GP G G G P + P G A+G P +G G
Sbjct: 693 PAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD----RGDA 748
Query: 97 GPQEAKKKP--DGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPT 154
GP+ A P DG + G G PG PA G GE P PT
Sbjct: 749 GPKGADGSPGKDGVRGLTGPIGP--------PG-------PAGAPGDKGESGPSGPAGPT 793
Query: 155 GHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTG 214
G P +R PG P G Q G G+ D G + A P G
Sbjct: 794 GAR--GAPGDRGEPG-PPGPAGFAGPPGADGQP-GAKGEPGDAGAKGDAGPP-GPAGPAG 848
Query: 215 NGHCQDGQRQTAQQIRHGQVEQPGGT-HPPAGHLPSHPGHHGIARHPH------QEDG-G 266
+ G PG T P A PG G A P +E G G
Sbjct: 849 PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908
Query: 267 IQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEA 326
+ E G A R G+ G A + + A ++ +P +
Sbjct: 909 PRGETGPAGR-PGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQR 967
Query: 327 GE-GFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGF 385
GE GFP L G + G QG + G PG GP + P G
Sbjct: 968 GERGFP-----GLPGPSGEPG-----------KQGPSGASGERGPPGPMGPPGLAGPPGE 1011
Query: 386 KHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGP-------AKGPV--VMLYNGREQDGQ 436
++ A GA+G +D + D G AG P A GPV R + G
Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGP 1071
Query: 437 RQAGEEVGYRQVEEPDGIDGPLG 459
VG P G GP G
Sbjct: 1072 AGPAGPVGPVGARGPAGPQGPRG 1094
Score = 42.4 bits (98), Expect = 0.001
Identities = 46/162 (28%), Positives = 59/162 (36%), Gaps = 33/162 (20%)
Query: 39 QGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA--GHGHQ 96
QGP G RG P + G P + +G P A G P ++G+ A G
Sbjct: 985 QGPSGASGERGPPGPMGPPGLAGPPGE-----SGREGAPGAEGSPGRDGSPGAKGDRGET 1039
Query: 97 GPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH 156
GP P GA GA PG V PA G GE P G
Sbjct: 1040 GPAGPPGAP-------GAPGA--------PG----PVGPAGKSGDRGETG------PAGP 1074
Query: 157 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGG 198
P P+ R P P+ + G E+ ++ D GI G + G
Sbjct: 1075 AGPVGPVGARGPAGPQGPRGDKG-ETGEQGDRGIKGHRGFSG 1115
Score = 41.6 bits (96), Expect = 0.002
Identities = 109/455 (23%), Positives = 147/455 (32%), Gaps = 45/455 (9%)
Query: 24 AAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCP----ADKKPHHNGCAQRPAA 79
A ++G+A +G P+G GVRG P G AD +P G P
Sbjct: 348 AVGAKGEAGPQG--PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405
Query: 80 SGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG 139
+G P G G QGP P G+ GA G+ V + P
Sbjct: 406 AGAPGFPGARGPS-GPQGPG-GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463
Query: 140 GGHGEQQGQCPGCPTGHLHPARPLNRRPPGR-----------PESQEAEVGTESCQEQDA 188
G G++ + PTG P P R PG P+ E G+ A
Sbjct: 464 GEEGKRGARGEPGPTGL--PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG----PA 517
Query: 189 GIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGH-- 246
G G + G RP TG+ +T GQ +PG PP
Sbjct: 518 GPKGSPGEAG-RPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQ 576
Query: 247 --LPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADR 304
+ PG G A P G ERG V G GA+ + A P A
Sbjct: 577 AGVMGFPGPKGAAGEP-----GKAGERG----VPGPPGAVGPAGKDGEAGAQGPPGPAGP 627
Query: 305 IVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLI 364
+ + Q +P AG P V + A G +G
Sbjct: 628 AGERGEQGPAGSPGFQGLPGPAG---PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE 684
Query: 365 QQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPV 424
+ +G PG AGP G + GA G ++ G + AAG P GP
Sbjct: 685 RGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLP--GPK 742
Query: 425 VMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
+ + G++ G R + P G GP G
Sbjct: 743 GDRGDAGPKGADGSPGKD-GVRGLTGPIGPPGPAG 776
Score = 33.5 bits (75), Expect = 0.55
Identities = 39/138 (28%), Positives = 55/138 (39%), Gaps = 16/138 (11%)
Query: 325 EAGEGFPQSA-LEALAGHHVDDGVDAAV-DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAP 382
+ G P +A L + GH G+D A D G +G + G PG+ G + P
Sbjct: 250 QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKG------EPGSPGENGAPGQMGP 303
Query: 383 DGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPA-KGPVVMLYNGREQDGQRQAGE 441
G ++ GA G AG ++G AAG P GP + +AG
Sbjct: 304 RGLPGERGRPGAPG----PAG--ARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGP 357
Query: 442 EVGYRQVEEPDGIDGPLG 459
+ G R E P G+ G G
Sbjct: 358 Q-GPRGSEGPQGVRGEPG 374
Score = 32.0 bits (71), Expect = 1.6
Identities = 33/115 (28%), Positives = 39/115 (33%), Gaps = 9/115 (7%)
Query: 354 GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG--------GQEQDAGVH 405
G+ G + +G G AGP P G AVGA G G E GV
Sbjct: 311 GRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR 370
Query: 406 VEQDEGGQDAAGGPAKGPVVMLYNG-REQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
E G A GPA P G + +G G+ P G GP G
Sbjct: 371 GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG 425
>gi|239757829 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 35/195 (17%)
Query: 54 HQPQQVVGCPADKKPHHN-----GCAQRPAASGCP--AQEGTVAAGHGHQGPQEAKKKPD 106
HQ QV+G PA+ K HH+ Q P A G Q+ +A GH QG Q+A
Sbjct: 21 HQHHQVIGGPAEGKGHHDHHHQPHGPQAPLAPGNQQHGQDVGIAVGHDQQGQQKA----- 75
Query: 107 GSHRILGAGGAAVVHHTLQPGWEVLLVQPAV----------DGGGHGEQQGQCPGCPTGH 156
SH++ A H WEV+L V D GE+Q + P G
Sbjct: 76 -SHQLQHPQSRAA--HL----WEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGE 128
Query: 157 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAS--TG 214
H R G + V ++ Q++ + + ++G T H G
Sbjct: 129 GHAGRGPPAVELGGMNYVQVAVKADAGQQEGSCVEVDVEEG----TCHFAEARAKDPLDG 184
Query: 215 NGHCQDGQRQTAQQI 229
+ HC + Q Q Q++
Sbjct: 185 SVHCPERQCQHQQRV 199
Score = 36.6 bits (83), Expect = 0.065
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 346 GVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEV------LAPDGFKHQQKAVGADGGQE 399
GV+A V VG+ + + + +Q E QAG + G + Q AV AD GQ+
Sbjct: 98 GVEALVVVGRQEDEVWEGEKQAEPPDSQAGEGHAGRGPPAVELGGMNYVQVAVKADAGQQ 157
Query: 400 QDAGVHVEQDEGGQDAAGGPAKGPV 424
+ + V V+ +EG A AK P+
Sbjct: 158 EGSCVEVDVEEGTCHFAEARAKDPL 182
>gi|239752340 PREDICTED: hypothetical protein XP_002348205 [Homo
sapiens]
Length = 218
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 35/195 (17%)
Query: 54 HQPQQVVGCPADKKPHHN-----GCAQRPAASGCP--AQEGTVAAGHGHQGPQEAKKKPD 106
HQ QV+G PA+ K HH+ Q P A G Q+ +A GH QG Q+A
Sbjct: 37 HQHHQVIGGPAEGKGHHDHHHQPHGPQAPLAPGNQQHGQDVGIAVGHDQQGQQKA----- 91
Query: 107 GSHRILGAGGAAVVHHTLQPGWEVLLVQPAV----------DGGGHGEQQGQCPGCPTGH 156
SH++ A H WEV+L V D GE+Q + P G
Sbjct: 92 -SHQLQHPQSRAA--HL----WEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGE 144
Query: 157 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAS--TG 214
H R G + V ++ Q++ + + ++G T H G
Sbjct: 145 GHAGRGPPAVELGGMNYVQVAVKADAGQQEGSCVEVDVEEG----TCHFAEARAKDPLDG 200
Query: 215 NGHCQDGQRQTAQQI 229
+ HC + Q Q Q++
Sbjct: 201 SVHCPERQCQHQQRV 215
Score = 36.6 bits (83), Expect = 0.065
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 346 GVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEV------LAPDGFKHQQKAVGADGGQE 399
GV+A V VG+ + + + +Q E QAG + G + Q AV AD GQ+
Sbjct: 114 GVEALVVVGRQEDEVWEGEKQAEPPDSQAGEGHAGRGPPAVELGGMNYVQVAVKADAGQQ 173
Query: 400 QDAGVHVEQDEGGQDAAGGPAKGPV 424
+ + V V+ +EG A AK P+
Sbjct: 174 EGSCVEVDVEEGTCHFAEARAKDPL 198
>gi|239746853 PREDICTED: hypothetical protein XP_002343864 [Homo
sapiens]
Length = 218
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 35/195 (17%)
Query: 54 HQPQQVVGCPADKKPHHN-----GCAQRPAASGCP--AQEGTVAAGHGHQGPQEAKKKPD 106
HQ QV+G PA+ K HH+ Q P A G Q+ +A GH QG Q+A
Sbjct: 37 HQHHQVIGGPAEGKGHHDHHHQPHGPQAPLAPGNQQHGQDVGIAVGHDQQGQQKA----- 91
Query: 107 GSHRILGAGGAAVVHHTLQPGWEVLLVQPAV----------DGGGHGEQQGQCPGCPTGH 156
SH++ A H WEV+L V D GE+Q + P G
Sbjct: 92 -SHQLQHPQSRAA--HL----WEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGE 144
Query: 157 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAS--TG 214
H R G + V ++ Q++ + + ++G T H G
Sbjct: 145 GHAGRGPPAVELGGMNYVQVAVKADAGQQEGSCVEVDVEEG----TCHFAEARAKDPLDG 200
Query: 215 NGHCQDGQRQTAQQI 229
+ HC + Q Q Q++
Sbjct: 201 SVHCPERQCQHQQRV 215
Score = 36.6 bits (83), Expect = 0.065
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 346 GVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEV------LAPDGFKHQQKAVGADGGQE 399
GV+A V VG+ + + + +Q E QAG + G + Q AV AD GQ+
Sbjct: 114 GVEALVVVGRQEDEVWEGEKQAEPPDSQAGEGHAGRGPPAVELGGMNYVQVAVKADAGQQ 173
Query: 400 QDAGVHVEQDEGGQDAAGGPAKGPV 424
+ + V V+ +EG A AK P+
Sbjct: 174 EGSCVEVDVEEGTCHFAEARAKDPL 198
>gi|239755481 PREDICTED: similar to Putative uncharacterized protein
ENSP00000334305 [Homo sapiens]
Length = 771
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/186 (27%), Positives = 68/186 (36%), Gaps = 23/186 (12%)
Query: 15 RREEEHGIEA--AVSEGKAHDEG-FSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHN 71
+ EEEHG++ +V E DEG G + C G + ++ G +
Sbjct: 46 QEEEEHGVKGVESVLEKGVLDEGVLEAWGCCRRCRHAGWNRSQPSPELAGAVVHARAPAV 105
Query: 72 GCAQRPAASGC---------PAQEGTVAAGHGHQGP-QEAKKKPDGSHRIL--GAGGAAV 119
GC QR P QE P E +KP+GS + G G AV
Sbjct: 106 GCRQRSGHLHVRLKQRLLERPCQEPLGKKYQLELPPLYERARKPEGSKNLPADGQGLRAV 165
Query: 120 VHHTLQPGWE-------VLLVQPAVDGGGHGEQQGQCPGCPTGHLH-PARPLNRRPPGRP 171
P W PA + G G+ QGQ P T HL P P +P
Sbjct: 166 RADAALPVWPGGPGRPGSRAHLPAPEAGAEGQHQGQWPPADTRHLRTPKWPYKVVTEEKP 225
Query: 172 ESQEAE 177
E++EAE
Sbjct: 226 EAEEAE 231
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 40.8 bits (94), Expect = 0.003
Identities = 108/434 (24%), Positives = 135/434 (31%), Gaps = 75/434 (17%)
Query: 40 GPGQECGVRGRHSEHQPQQVVGCPADK-KPHHNGCAQRPAASGCPAQEGTVAAGHGHQGP 98
G E G RG E + G P K + +G P A+G P G A G +GP
Sbjct: 438 GAKGEPGPRGERGE---AGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAP-GFRGP 493
Query: 99 Q-----EAKKKPDGSHRILGAGG----AAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQC 149
+K P G G G A PG + P GG + +
Sbjct: 494 AGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK--- 550
Query: 150 PGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDA--GIHGQQDD-GGQRPTAHCT 206
PG P RP P G P Q +G + D G +G++ GG P
Sbjct: 551 PGPPGSQGESGRPGPPGPSG-PRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG--- 606
Query: 207 IRPVASTGNGHCQDGQRQTAQQIRHGQVEQPG--------GTHPPAGH--LPSHPGHHGI 256
P G Q T G PG GT P G P PG G
Sbjct: 607 --PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD 664
Query: 257 ARHPH----QEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIV--PHSG 310
A P + D G ERG G AGA +R A P + P
Sbjct: 665 AGAPGAPGGKGDAGAPGERGPP----GLAGA-----PGLRGGAGPPGPEGGKGAAGPPGP 715
Query: 311 SWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAV------------------- 351
+ T Q +P E G G + G G D
Sbjct: 716 PGAAGTPGLQGMPGERG-GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774
Query: 352 ---DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQ 408
D G+G G+ I G PG+ G + P GF G GG + + G E+
Sbjct: 775 QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGG-KGERGAPGEK 833
Query: 409 DEGGQDAAGGPAKG 422
EGG GP G
Sbjct: 834 GEGGPPGVAGPPGG 847
Score = 40.0 bits (92), Expect = 0.006
Identities = 87/351 (24%), Positives = 117/351 (33%), Gaps = 46/351 (13%)
Query: 84 AQEGTVAAGHGHQGPQEAKK---KPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 140
AQ+ V G H G A + KP+ + G+ + + E+ P +
Sbjct: 23 AQQEAVEGGCSHLGQSYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIP-- 80
Query: 141 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQ-DDGGQ 199
GE CP PT P RP N + P P+ G + D GI GQ G
Sbjct: 81 -FGECCAVCPQPPT---APTRPPNGQGPQGPKGDPGPPGIPG-RNGDPGIPGQPGSPGSP 135
Query: 200 RPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARH 259
P C P D + G PG PAG P PG G + H
Sbjct: 136 GPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPG----PAGP-PGPPGPPGTSGH 190
Query: 260 PHQEDG----GIQWERGHA--QRVDGQAGAIQAVHRAVRE-VAVIPILVADRIVPHSGSW 312
P G E G A G GAI A ++ + P +R +P
Sbjct: 191 PGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGI 250
Query: 313 VSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPG 372
P +P GFP + GH DG + KG+T G ++ + G PG
Sbjct: 251 KGPA----GIP-----GFP-----GMKGHRGFDGRNGE----KGET-GAPGLKGENGLPG 291
Query: 373 QAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGP 423
+ G + P G ++ G G AG G D GP P
Sbjct: 292 ENGAPGPMGPRGAPGERGRPGLPGA----AGARGNDGARGSDGQPGPPGPP 338
Score = 34.7 bits (78), Expect = 0.25
Identities = 113/469 (24%), Positives = 149/469 (31%), Gaps = 105/469 (22%)
Query: 37 SPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA----- 91
SP GPG + G+ Q G P P +G +P G P +G A
Sbjct: 541 SPGGPGSD----GKPGPPGSQGESGRPGPPGP--SGPRGQPGVMGFPGPKGNDGAPGKNG 594
Query: 92 ------GHGHQGP--QEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG-GH 142
G G QGP + + P G G GG T PG + L P G G
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDK--GDTGPPGPQGLQGLPGTGGPPGE 652
Query: 143 GEQQGQ--------CPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQ 194
+ G+ PG P G P R PPG + G AG G
Sbjct: 653 NGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG--------AGPPG-- 702
Query: 195 DDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL--PSHPG 252
+GG+ A T G+R G + PG P G P PG
Sbjct: 703 PEGGKGAAGPPGPPGAAGTPGLQGMPGER--------GGLGSPG----PKGDKGEPGGPG 750
Query: 253 HHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSW 312
G+ G RG + A Q + +P + R P
Sbjct: 751 ADGVP--------GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802
Query: 313 VSPTESCQHVPEEAGEGFPQSALEALAGHHVDDG----VDAAVDVGKGDTQGVQLIQQQE 368
P P A GFP G + + G A + G+G GV
Sbjct: 803 TGP-------PGPA--GFP-----GAPGQNGEPGGKGERGAPGEKGEGGPPGV------A 842
Query: 369 GDPGQAGPSEVLAPDGFKHQQKAVGADG--------------GQEQDAGVHVEQDEGGQD 414
G PG +GP+ P G K ++ + G G G + G G+D
Sbjct: 843 GPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD 902
Query: 415 AAGGPA---KGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGL 460
GPA P +G + D Q GE+ G + P G GPLG+
Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDA-GQPGEK-GSPGAQGPPGAPGPLGI 949
Score = 33.5 bits (75), Expect = 0.55
Identities = 31/106 (29%), Positives = 40/106 (37%), Gaps = 12/106 (11%)
Query: 369 GDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLY 428
G PG AGP P G + G+ G Q E GQ GP P +
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG-------EPGQAGPSGPPGPPGAIGP 223
Query: 429 NGRE-QDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQH 473
+G +DG+ G R + P GI GP G+ P G+ H
Sbjct: 224 SGPAGKDGESGRPGRPGERGLPGPPGIKGPAGI----PGFPGMKGH 265
Score = 32.0 bits (71), Expect = 1.6
Identities = 64/262 (24%), Positives = 80/262 (30%), Gaps = 47/262 (17%)
Query: 38 PQGPGQECGVRGRHSEHQPQQVVGCPADK-KPHHNGCAQRPAASGCPAQEGT-------- 88
P GP G G P+ G P +K P G P G G
Sbjct: 904 PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPG 963
Query: 89 VAAGHGHQGPQEAK--------------KKPDGSHRILG-AGGAAVVHHTLQPGWEVLLV 133
+ G GPQ K + P G + G AG A PG + L
Sbjct: 964 MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGL-- 1021
Query: 134 QPAVDG--GGHGEQ-QGQCPGCPTGHLHPARPLNRRPPGR-----------PESQEAEVG 179
P DG GG G++ + PG P HP P P G+ P G
Sbjct: 1022 -PGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080
Query: 180 TESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGG 239
+ G G + + G+R A GN QQ G + PG
Sbjct: 1081 SRGAPGPQ-GPRGDKGETGERGAAGIKGHR-GFPGNPGAPGSPGPAGQQ---GAIGSPGP 1135
Query: 240 THPPAGHLPS-HPGHHGIARHP 260
P PS PG G + HP
Sbjct: 1136 AGPRGPVGPSGPPGKDGTSGHP 1157
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/96 (31%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 365 QQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPV 424
Q G+PGQAGPS P G G D G+ G E+ G GPA P
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKD-GESGRPGRPGERGLPGPPGIKGPAGIPG 258
Query: 425 VMLYNG-REQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
G R DG+ E G ++ +G+ G G
Sbjct: 259 FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG 294
>gi|14249622 ajuba isoform 1 [Homo sapiens]
Length = 538
Score = 40.0 bits (92), Expect = 0.006
Identities = 45/138 (32%), Positives = 57/138 (41%), Gaps = 19/138 (13%)
Query: 74 AQRPAASGC--------PA--QEGTVA-AGHGHQGPQEAKKKPDGSHRILGAGGAAVVHH 122
AQRPA GC PA G +A AG G GP E + G H + G G A V
Sbjct: 216 AQRPAGFGCQESRHSYPPALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYGDCA-VGA 274
Query: 123 TLQPGWEVLLVQPAVDGGGHGEQQGQCPGC-PTGHLHPARPL----NRRPPGRPESQEAE 177
Q LL GG +G+ G P+G P P R PE++E
Sbjct: 275 RYQDELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDY 334
Query: 178 VGTESCQEQDAGIHGQQD 195
GT C + + GI+GQ +
Sbjct: 335 FGT--CIKCNKGIYGQSN 350
>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
Length = 689
Score = 40.0 bits (92), Expect = 0.006
Identities = 113/450 (25%), Positives = 147/450 (32%), Gaps = 102/450 (22%)
Query: 38 PQGPGQECGVRGRHSEHQPQQVVGCPADK-KPHHNGCAQRPAASG---CPAQEGTVAAGH 93
P G E G+RG + P G P KP G Q S CP
Sbjct: 126 PVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTN-----CPP 180
Query: 94 GHQGPQ--EAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPG 151
G +GP + K G ILG G H +PG P D G GEQ P
Sbjct: 181 GMKGPPGLQGVKGHAGKRGILGDPG-----HQGKPG-------PKGDVGASGEQGIPGPP 228
Query: 152 CPTG---HLHPARPLNRRPPGRPESQEAEVGTESCQEQD--------AGIHGQQDDGGQR 200
P G + A P P + +G ++ AG G + G R
Sbjct: 229 GPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIR 288
Query: 201 PTAHCTIRPVASTG----NGHCQDGQRQT-AQQIRHGQVEQPGGTHPPAGHLPSHPGHHG 255
T P +TG NG +DG T + GQ QPG P H G G
Sbjct: 289 GPQGIT-GPKGATGPPGING--KDGTPGTPGMKGSAGQAGQPGS--------PGHQGLAG 337
Query: 256 IARHPHQEDG-GIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVS 314
+ P + G G Q E G Q + G +G
Sbjct: 338 VPGQPGTKGGPGDQGEPG-PQGLPGFSGP------------------------------- 365
Query: 315 PTESCQHVPEEAGEGFPQSAL--EALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPG 372
P + GE P+ + + + G D G V G+ QG Q + ++G PG
Sbjct: 366 --------PGKEGEPGPRGEIGPQGIMGQKGDQGERGPV--GQPGPQGRQGPKGEQGPPG 415
Query: 373 QAGPSEVLAPDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNG 430
GP + G K G G G AG+ E+ E G+ GP KG
Sbjct: 416 IPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP-KGQ----QGV 470
Query: 431 REQDGQRQAGEEVGYRQVEEPDGIDGPLGL 460
R + G + G V+ G GP GL
Sbjct: 471 RGEPGYPGPSGDAGAPGVQGYPGPPGPRGL 500
Score = 31.6 bits (70), Expect = 2.1
Identities = 70/281 (24%), Positives = 89/281 (31%), Gaps = 67/281 (23%)
Query: 38 PQGPGQECGVRGRHSEHQPQQVVGCPADK----KPHHNGCAQRPAASGCPAQEGTVAAGH 93
PQG G +G PQ + G DK K G P +G P ++G
Sbjct: 401 PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGES- 459
Query: 94 GHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCP 153
G GP+ G + G G PG P+ D G G Q P P
Sbjct: 460 GEPGPK-------GQQGVRGEPG--------YPG-------PSGDAGAPGVQGYPGPPGP 497
Query: 154 TGHLHPARPLNRRPPGRPESQEAE-----------VGTESCQEQDA-------------- 188
G NR PG+P Q E V + QEQ A
Sbjct: 498 RGLAG-----NRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAV 552
Query: 189 GIHGQQDDGG-------QRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTH 241
G+ G G Q P H R V Q G T + + G+ PG
Sbjct: 553 GMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGN--TGPKGKRGEKGDPGEVG 610
Query: 242 PPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAG 282
+P PG G+ P Q G +RG + G+AG
Sbjct: 611 RGHPGMPGPPGIPGLPGRPGQAINGKDGDRG-SPGAPGEAG 650
>gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens]
Length = 610
Score = 39.7 bits (91), Expect = 0.008
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 58/303 (19%)
Query: 167 PPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTA 226
PPG+P Q G G++ G+ P C A+ + + + +
Sbjct: 168 PPGQPGPQ--------------GQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQS 213
Query: 227 QQIRHGQVEQPGGTHP--PAGH--LPSHPGHHGIARHPHQE-DGGIQWERGHAQR----- 276
Q G PG P P GH LP G G+ P + D GIQ G
Sbjct: 214 QASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPG 273
Query: 277 VDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALE 336
+ G+ GA A AV + P + + E+ EG P L
Sbjct: 274 MPGKHGAKGAPGIAVAGMKGEPGIPGTK------------------GEKGAEGSP--GLP 313
Query: 337 ALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG 396
L G + G DA +G G + + G PG GP G Q G G
Sbjct: 314 GLLGQKGEKG-DAGNSIGGG--------RGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPG 364
Query: 397 GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDG 456
+ + + +G + + G P KG +V YNG +A +E+ + P G+ G
Sbjct: 365 DKGERGAAGEQGPDGPKGSKGEPGKGEMVD-YNG----NINEALQEIRTLALMGPPGLPG 419
Query: 457 PLG 459
+G
Sbjct: 420 QIG 422
>gi|22027605 alpha 1 type XIII collagen isoform 17 [Homo sapiens]
Length = 657
Score = 39.7 bits (91), Expect = 0.008
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 58/303 (19%)
Query: 167 PPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTA 226
PPG+P Q G G++ G+ P C A+ + + + +
Sbjct: 159 PPGQPGPQ--------------GQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQS 204
Query: 227 QQIRHGQVEQPGGTHP--PAGH--LPSHPGHHGIARHPHQE-DGGIQWERGHAQR----- 276
Q G PG P P GH LP G G+ P + D GIQ G
Sbjct: 205 QASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPG 264
Query: 277 VDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALE 336
+ G+ GA A AV + P + + E+ EG P L
Sbjct: 265 MPGKHGAKGAPGIAVAGMKGEPGIPGTK------------------GEKGAEGSP--GLP 304
Query: 337 ALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG 396
L G + G DA +G G + + G PG GP G Q G G
Sbjct: 305 GLLGQKGEKG-DAGNSIGGG--------RGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPG 355
Query: 397 GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDG 456
+ + + +G + + G P KG +V YNG +A +E+ + P G+ G
Sbjct: 356 DKGERGAAGEQGPDGPKGSKGEPGKGEMVD-YNG----NINEALQEIRTLALMGPPGLPG 410
Query: 457 PLG 459
+G
Sbjct: 411 QIG 413
>gi|22027601 alpha 1 type XIII collagen isoform 15 [Homo sapiens]
Length = 668
Score = 39.7 bits (91), Expect = 0.008
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 58/303 (19%)
Query: 167 PPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTA 226
PPG+P Q G G++ G+ P C A+ + + + +
Sbjct: 197 PPGQPGPQ--------------GQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQS 242
Query: 227 QQIRHGQVEQPGGTHP--PAGH--LPSHPGHHGIARHPHQE-DGGIQWERGHAQR----- 276
Q G PG P P GH LP G G+ P + D GIQ G
Sbjct: 243 QASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPG 302
Query: 277 VDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALE 336
+ G+ GA A AV + P + + E+ EG P L
Sbjct: 303 MPGKHGAKGAPGIAVAGMKGEPGIPGTK------------------GEKGAEGSP--GLP 342
Query: 337 ALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG 396
L G + G DA +G G + + G PG GP G Q G G
Sbjct: 343 GLLGQKGEKG-DAGNSIGGG--------RGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPG 393
Query: 397 GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDG 456
+ + + +G + + G P KG +V YNG +A +E+ + P G+ G
Sbjct: 394 DKGERGAAGEQGPDGPKGSKGEPGKGEMVD-YNG----NINEALQEIRTLALMGPPGLPG 448
Query: 457 PLG 459
+G
Sbjct: 449 QIG 451
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 39.7 bits (91), Expect = 0.008
Identities = 38/140 (27%), Positives = 48/140 (34%), Gaps = 26/140 (18%)
Query: 139 GGGHGEQQGQCPGCPTG---HLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQD 195
GG + P P G H HP +P PP P+ ++ HG
Sbjct: 266 GGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHS-------------HGPPL 312
Query: 196 DGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL-PSHP-GH 253
G P + P++ + CQ T RH HP H HP GH
Sbjct: 313 PQGPPP-----LLPMSCSS---CQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGH 364
Query: 254 HGIARHPHQEDGGIQWERGH 273
H A HPH+ D Q GH
Sbjct: 365 HPHAHHPHEHDTHRQHPHGH 384
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
Length = 1629
Score = 39.3 bits (90), Expect = 0.010
Identities = 124/525 (23%), Positives = 175/525 (33%), Gaps = 88/525 (16%)
Query: 4 QQQNLVSTGSNRREEEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCP 63
+ Q+ + G + E G A + G + P+GP G G P VG P
Sbjct: 262 EPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGP---VGDP 318
Query: 64 ADKKPHHNGCAQRPAASGCPAQEGT-------VAAGHGHQGPQEAKKKPDGSH-----RI 111
++ P G A P + G P GT +G G +GP A ++ R+
Sbjct: 319 GERGPP--GRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 376
Query: 112 LGAGGAAVVHHTLQPGWEVLLVQPAVDG--GGHGEQQGQCPGCPTGHLHPARPLNRRPPG 169
G + +T +PG L QP G G G+ Q P P G P RR
Sbjct: 377 ALRGPPGPMGYTGRPG---PLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 433
Query: 170 RPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQI 229
+ G + D G G G++ H +DG+R +I
Sbjct: 434 GADGARGMPGDPGVKG-DRGFDGLPGLPGEK--GHRGDTGAQGLPGPPGEDGERGDDGEI 490
Query: 230 RHGQVEQPGGTHP--------PAGHLPSHPGHHGI--------ARHPHQEDG--GIQWER 271
G PG + P P G +P PG G+ + P E G G Q
Sbjct: 491 --GPRGLPGESGPRGLLGPKGPPG-IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 547
Query: 272 GHAQRVDGQAGAIQAV-HRAVREVAVIPILVADRIVP-HSGSWVSPTESCQHVPE--EAG 327
G Q + G GAI + + +P + P H G P P +
Sbjct: 548 G-TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGP 606
Query: 328 EGFPQ-------SALEALAGHHVDDGVDAAV----DVG-KGDTQGVQLIQQQ-----EGD 370
G+P + L GH + G D D+G KGD V + + EG
Sbjct: 607 LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP 666
Query: 371 PGQAGPSEVLAPDGFKHQQKAVGADG--------------GQEQDAGVHVEQDEGGQDAA 416
G+ GP+ P G ++ +G G G G E+ G
Sbjct: 667 KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 726
Query: 417 GGP--AKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
GP +GP R Q G R A + G + DG GP G
Sbjct: 727 SGPRGERGPT----GPRGQRGPRGATGKSGAKGTSGGDGPHGPPG 767
Score = 36.6 bits (83), Expect = 0.065
Identities = 94/381 (24%), Positives = 119/381 (31%), Gaps = 70/381 (18%)
Query: 28 EGKAHDEG-FSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 86
+G+ D G P GP G G + PQ G + P G P SG P +
Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP--GEKGEPGESGSPGIQ 1117
Query: 87 GT--VAAGHGHQGP-----QEAKKKPDGSHRILG----AGGAAVVHHTLQPGWEVLLVQP 135
G V G +G Q + P G G G V PG P
Sbjct: 1118 GEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG-------P 1170
Query: 136 AVDGGGHGEQ-------------QGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTES 182
+GG G+ Q PG PTG P PL +R P E G +
Sbjct: 1171 PGEGGPRGQDGAKGDRGEDGEPGQPGSPG-PTGENGPPGPLGKRGPAGSPGSEGRQGGKG 1229
Query: 183 CQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHP 242
+ I G P P G + QQ R G Q G P
Sbjct: 1230 AKGDPGAIGAPGKTGPVGPAG-----PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGP 1284
Query: 243 PAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVA 302
P PG G D G + E+GH G G I +
Sbjct: 1285 VGP--PGLPGLRG--------DAGAKGEKGH----PGLIGLIGPPGEQGEK--------G 1322
Query: 303 DRIVPHSGSWVSPTESCQ-HVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGV 361
DR +P G SP + + +P +G P L G G A G G +G
Sbjct: 1323 DRGLP--GPQGSPGQKGEMGIPGASGPIGP-GGPPGLPGPAGPKGAKGA--TGPGGPKGE 1377
Query: 362 QLIQQQEGDPGQAGPSEVLAP 382
+ +Q G PG P EV+ P
Sbjct: 1378 KGVQGPPGHPGP--PGEVIQP 1396
Score = 35.4 bits (80), Expect = 0.15
Identities = 73/300 (24%), Positives = 106/300 (35%), Gaps = 38/300 (12%)
Query: 170 RPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQI 229
RP++Q+ S Q+Q + +H Q+ Q AH G++ +
Sbjct: 235 RPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAH----------GPRGLKGEKGEPAVL 284
Query: 230 RHGQ-VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQR--VDGQAGAIQA 286
G VE P G PAG + G GI +P G ERG R + G GA
Sbjct: 285 EPGMLVEGPPGPEGPAGLI----GPPGIQGNPGPV--GDPGERGPPGRAGLPGSDGAPGP 338
Query: 287 VHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDG 346
++ ++P G P + Q E + Q A AL G G
Sbjct: 339 PGTSL----MLPFRFGS-----GGGDKGPVVAAQ---EAQAQAILQQARLALRGPPGPMG 386
Query: 347 VDAAVD-VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVH 405
+G+ + G++ G G GP + P G ++ GADG +
Sbjct: 387 YTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPG 446
Query: 406 VEQDEGGQDAAGGPA-KG-----PVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
V+ D G G P KG L +DG+R E+G R + G G LG
Sbjct: 447 VKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLG 506
Score = 33.5 bits (75), Expect = 0.55
Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 6/107 (5%)
Query: 359 QGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGV-----HVEQDEGGQ 413
QG+ ++G+ G GP P G + GADG Q GV E+ E G+
Sbjct: 1051 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1110
Query: 414 DAAGGPAKGPVVMLYNG-REQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
+ G P V G R + G+ E G + P G DGP G
Sbjct: 1111 SGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1157
Score = 33.1 bits (74), Expect = 0.72
Identities = 111/477 (23%), Positives = 145/477 (30%), Gaps = 84/477 (17%)
Query: 29 GKAHDEGFS----PQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHN----GCAQRPAAS 80
G+ + GF P GP G +G E P G P P G A +
Sbjct: 800 GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 859
Query: 81 GCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 140
G P G G GP + P G + G G + P P G
Sbjct: 860 GDPGPPGAP----GKDGPAGLRGFP-GERGLPGTAGGPGLKGNEGPSG------PPGPAG 908
Query: 141 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 200
GE+ G P G P RP + PPG G + + I DG Q
Sbjct: 909 SPGERGAAGSGGPIGP--PGRPGPQGPPGA-------AGEKGVPGEKGPIGPTGRDGVQG 959
Query: 201 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPG--------GTHPPAGHLPSHPG 252
P + A +DG + G+V PG G H P P PG
Sbjct: 960 PVG---LPGPAGPPGVAGEDGDK--------GEVGDPGQKGTKGNKGEHGP----PGPPG 1004
Query: 253 HHGIARHPHQE--DG--GIQWERGH--AQRVDGQAG--------AIQAVHRAVREVA--- 295
G P DG G + +GH A+ +G G +Q + E
Sbjct: 1005 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064
Query: 296 -VIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDV- 353
V P+ P + + + Q P G P + G G+ V
Sbjct: 1065 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE-KGEPGESGSPGIQGEPGVK 1123
Query: 354 GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG-----------GQEQDA 402
G +G + Q G+PG GP DG K VG G GQ+
Sbjct: 1124 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1183
Query: 403 GVHVEQDEGGQDAAGGPA--KGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGP 457
G E E GQ + GP GP L G + G +P I P
Sbjct: 1184 GDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAP 1240
Score = 31.2 bits (69), Expect = 2.7
Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 6/96 (6%)
Query: 364 IQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGP 423
+Q G PG AGP V DG K + VG D GQ+ G E G GP P
Sbjct: 957 VQGPVGLPGPAGPPGVAGEDGDKGE---VG-DPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1012
Query: 424 VVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 459
+G + G R G + E G +GP G
Sbjct: 1013 GAAGADG--EPGARGPQGHFGAKGDEGTRGFNGPPG 1046
Score = 30.4 bits (67), Expect = 4.7
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 354 GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQ 413
G+ +G + + G PG GP+ P G ++ G+ G + + G + D G
Sbjct: 1178 GQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPG-- 1235
Query: 414 DAAGGPAK-GPV 424
A G P K GPV
Sbjct: 1236 -AIGAPGKTGPV 1246
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 39.3 bits (90), Expect = 0.010
Identities = 69/329 (20%), Positives = 126/329 (38%), Gaps = 37/329 (11%)
Query: 167 PPGRPES--QEAEVGTESCQEQDAGIHGQQDDG-GQRPTAHCTIRPVASTGNGHCQDGQR 223
P GR + +E G E Q+++ G++D G G+ + +A +DG+
Sbjct: 651 PEGRGDGTCEEGSSGAEHWQDEERE-KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEE 709
Query: 224 QTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIA-RHPHQEDGGIQWERGHAQRVDGQA- 281
Q ++ G ++ G G R +E G E G + V+G+
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGERE 769
Query: 282 ---GAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEAL 338
G + RA +E + TE EE GE
Sbjct: 770 KEEGERKKEERAGKEEK------GEEEGDQGEGEEEETEGRGEEKEEGGE---------- 813
Query: 339 AGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQ 398
V+ G V+ GKG+ + + ++ EG+ + G E +G + + + G + G+
Sbjct: 814 ----VEGG---EVEEGKGEREEEE--EEGEGEE-EEGEGEEEEGEGEEEEGEGKGEEEGE 863
Query: 399 EQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPL 458
E + E+ EG + G +G G E++G+ + GEE G + EE +G +G
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE-GEEEGEGEGEEEEG-EGKG 921
Query: 459 GLECRHPDHQGIAQHSHQEDDCKDDQGQD 487
E + +G + E + + +G++
Sbjct: 922 EEEGEEGEGEGEEEEGEGEGEDGEGEGEE 950
Score = 34.7 bits (78), Expect = 0.25
Identities = 62/323 (19%), Positives = 121/323 (37%), Gaps = 31/323 (9%)
Query: 169 GRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQ 228
G+ E + EV E +E++ G +++ G+ G G+ + +
Sbjct: 755 GKEEGEGEEVEGE--REKEEGERKKEERAGKE-----------EKGEEEGDQGEGEEEET 801
Query: 229 IRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVH 288
G+ ++ GG G + G R +E+G + E G + +G+ +
Sbjct: 802 EGRGEEKEEGG-EVEGGEVEEGKGE----REEEEEEGEGEEEEGEGEEEEGEGEEEEGEG 856
Query: 289 RAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVD 348
+ E G E + EE GEG + G +G
Sbjct: 857 KGEEEGEE----GEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEG 912
Query: 349 AAVD-VGKGDTQGVQLI---QQQEGD-PGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAG 403
+ GKG+ +G + +++EG+ G+ G E +G ++ G G+E+ G
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972
Query: 404 VHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECR 463
E+ EG + G +G G E+ + GEE G + EE + + +E
Sbjct: 973 -EGEEGEGEGEEEEGEGEGEEE---EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGE 1028
Query: 464 HPDHQGIAQHSHQEDDCKDDQGQ 486
+ +G + +E + ++ +G+
Sbjct: 1029 EGEGEGEEEEGEEEGEEREKEGE 1051
Score = 33.1 bits (74), Expect = 0.72
Identities = 54/277 (19%), Positives = 93/277 (33%), Gaps = 55/277 (19%)
Query: 12 GSNRREEEHG-IEAA-VSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPH 69
G +EE G +E V EGK E +G G+E G E + ++ G
Sbjct: 803 GRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG-------- 854
Query: 70 HNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWE 129
G + G +EG G G + E + + +G G G
Sbjct: 855 -EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGE----GEG-------------- 895
Query: 130 VLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQ----EAEVGTESCQE 185
+G G GE++G+ G G E + E E G +E
Sbjct: 896 -----EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEE 950
Query: 186 QDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAG 245
++ G++++G G G ++G+ + ++ G+ E+ G G
Sbjct: 951 EEGEWEGEEEEGEGEG---------EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE--EG 999
Query: 246 HLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAG 282
G +E+G ++ E V+G+ G
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEGE------VEGEEG 1030
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.135 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,238,428
Number of Sequences: 37866
Number of extensions: 1802511
Number of successful extensions: 5752
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 4608
Number of HSP's gapped (non-prelim): 1215
length of query: 582
length of database: 18,247,518
effective HSP length: 108
effective length of query: 474
effective length of database: 14,157,990
effective search space: 6710887260
effective search space used: 6710887260
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.