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Search of human proteins with 118402590
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118402590 myosin XV [Homo sapiens]
(3530 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118402590 myosin XV [Homo sapiens] 7212 0.0
gi|122937512 myosin VIIB [Homo sapiens] 616 e-175
gi|154354979 myosin X [Homo sapiens] 594 e-169
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 573 e-162
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 573 e-162
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 573 e-162
gi|122937345 myosin VB [Homo sapiens] 512 e-144
gi|215982794 myosin VA isoform 2 [Homo sapiens] 511 e-144
gi|215982791 myosin VA isoform 1 [Homo sapiens] 511 e-144
gi|194328685 myosin IB isoform 1 [Homo sapiens] 502 e-141
gi|44889481 myosin IB isoform 2 [Homo sapiens] 502 e-141
gi|240120050 myosin IB isoform 1 [Homo sapiens] 502 e-141
gi|153945715 myosin VC [Homo sapiens] 500 e-141
gi|4885503 myosin IA [Homo sapiens] 489 e-137
gi|134288892 myosin IIIB isoform 2 [Homo sapiens] 482 e-135
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 479 e-134
gi|145275208 myosin IIIA [Homo sapiens] 476 e-133
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 474 e-133
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 474 e-133
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 474 e-133
gi|134288915 myosin IIIB isoform 1 [Homo sapiens] 472 e-132
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 471 e-132
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 471 e-132
gi|124494247 myosin IC isoform b [Homo sapiens] 467 e-131
gi|124494238 myosin IC isoform a [Homo sapiens] 467 e-131
gi|124494240 myosin IC isoform c [Homo sapiens] 467 e-131
gi|27544941 myosin IF [Homo sapiens] 463 e-129
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 460 e-128
gi|254028267 myosin 1H [Homo sapiens] 460 e-128
gi|51100974 myosin ID [Homo sapiens] 459 e-128
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 7212 bits (18711), Expect = 0.0
Identities = 3530/3530 (100%), Positives = 3530/3530 (100%)
Query: 1 MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFF 60
MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFF
Sbjct: 1 MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFF 60
Query: 61 WGLHTGPQKTKRKRKARTVLKSTSKLMTQMRMGKKKRAMKGKKPSFMVIRFPGRRGYGRL 120
WGLHTGPQKTKRKRKARTVLKSTSKLMTQMRMGKKKRAMKGKKPSFMVIRFPGRRGYGRL
Sbjct: 61 WGLHTGPQKTKRKRKARTVLKSTSKLMTQMRMGKKKRAMKGKKPSFMVIRFPGRRGYGRL 120
Query: 121 RPRARSLSKASTAINWLTKKFLLKKAEESGSEQATVDAWLQRSSSRMGSRKLPFPSGAEI 180
RPRARSLSKASTAINWLTKKFLLKKAEESGSEQATVDAWLQRSSSRMGSRKLPFPSGAEI
Sbjct: 121 RPRARSLSKASTAINWLTKKFLLKKAEESGSEQATVDAWLQRSSSRMGSRKLPFPSGAEI 180
Query: 181 LRPGGRLRRFPRSRSIYASGEPLGFLPFEDEAPFHHSGSRKSLYGLEGFQDLGEYYDYHR 240
LRPGGRLRRFPRSRSIYASGEPLGFLPFEDEAPFHHSGSRKSLYGLEGFQDLGEYYDYHR
Sbjct: 181 LRPGGRLRRFPRSRSIYASGEPLGFLPFEDEAPFHHSGSRKSLYGLEGFQDLGEYYDYHR 240
Query: 241 DGDDYYDRQSLHRYEEQEPYLAGLGPYSPAWPPYGDHYYGYPPEDPYDYYHPDYYGGPFD 300
DGDDYYDRQSLHRYEEQEPYLAGLGPYSPAWPPYGDHYYGYPPEDPYDYYHPDYYGGPFD
Sbjct: 241 DGDDYYDRQSLHRYEEQEPYLAGLGPYSPAWPPYGDHYYGYPPEDPYDYYHPDYYGGPFD 300
Query: 301 PGYTYGYGYDDYEPPYAPPSGYSSPYSYHDGYEGEAHPYGYYLDPYAPYDAPYPPYDLPY 360
PGYTYGYGYDDYEPPYAPPSGYSSPYSYHDGYEGEAHPYGYYLDPYAPYDAPYPPYDLPY
Sbjct: 301 PGYTYGYGYDDYEPPYAPPSGYSSPYSYHDGYEGEAHPYGYYLDPYAPYDAPYPPYDLPY 360
Query: 361 HTPYDVPYFDPYGVHYTVPYAEGVYGGGDEAIYPPEVPYFYPEESASAFVYPWVPPPIPS 420
HTPYDVPYFDPYGVHYTVPYAEGVYGGGDEAIYPPEVPYFYPEESASAFVYPWVPPPIPS
Sbjct: 361 HTPYDVPYFDPYGVHYTVPYAEGVYGGGDEAIYPPEVPYFYPEESASAFVYPWVPPPIPS 420
Query: 421 PHNPYAHAMDDIAELEEPEDAGVERQGTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLF 480
PHNPYAHAMDDIAELEEPEDAGVERQGTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLF
Sbjct: 421 PHNPYAHAMDDIAELEEPEDAGVERQGTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLF 480
Query: 481 PRPQVKLFGKEKLEVPLPPSLDIPLPLGDADEEEDEEELPPVSAVPYGHPFWGFLTPRQR 540
PRPQVKLFGKEKLEVPLPPSLDIPLPLGDADEEEDEEELPPVSAVPYGHPFWGFLTPRQR
Sbjct: 481 PRPQVKLFGKEKLEVPLPPSLDIPLPLGDADEEEDEEELPPVSAVPYGHPFWGFLTPRQR 540
Query: 541 NLQRALSAFGAHRGLGFGPEFGRPVPRPATSLARFLKKTLSEKKPIARLRGSQKARAGGP 600
NLQRALSAFGAHRGLGFGPEFGRPVPRPATSLARFLKKTLSEKKPIARLRGSQKARAGGP
Sbjct: 541 NLQRALSAFGAHRGLGFGPEFGRPVPRPATSLARFLKKTLSEKKPIARLRGSQKARAGGP 600
Query: 601 AVREAAYKRFGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPAPQPAPRTLSHWSAL 660
AVREAAYKRFGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPAPQPAPRTLSHWSAL
Sbjct: 601 AVREAAYKRFGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPAPQPAPRTLSHWSAL 660
Query: 661 LSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPPAPQASWWA 720
LSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPPAPQASWWA
Sbjct: 661 LSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPPAPQASWWA 720
Query: 721 FVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSL 780
FVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSL
Sbjct: 721 FVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSL 780
Query: 781 RSSPGLGYCSPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPL 840
RSSPGLGYCSPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPL
Sbjct: 781 RSSPGLGYCSPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPL 840
Query: 841 PGSPRPPSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAW 900
PGSPRPPSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAW
Sbjct: 841 PGSPRPPSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAW 900
Query: 901 RAPLEHRESPREPEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSRRGFSRPPPVP 960
RAPLEHRESPREPEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSRRGFSRPPPVP
Sbjct: 901 RAPLEHRESPREPEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSRRGFSRPPPVP 960
Query: 961 ENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEATLGD 1020
ENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEATLGD
Sbjct: 961 ENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEATLGD 1020
Query: 1021 PQLPAETKPPTPAPPKDVTPPKDITPPKDVLPEQKTLRPSLSYPLAACDQTRATWPPWHR 1080
PQLPAETKPPTPAPPKDVTPPKDITPPKDVLPEQKTLRPSLSYPLAACDQTRATWPPWHR
Sbjct: 1021 PQLPAETKPPTPAPPKDVTPPKDITPPKDVLPEQKTLRPSLSYPLAACDQTRATWPPWHR 1080
Query: 1081 WGTLPQAAAPLAPIRAPEPLPKGGERRQAAPGRFAVVMPRVQKLSSFQRVGPATLKPQVQ 1140
WGTLPQAAAPLAPIRAPEPLPKGGERRQAAPGRFAVVMPRVQKLSSFQRVGPATLKPQVQ
Sbjct: 1081 WGTLPQAAAPLAPIRAPEPLPKGGERRQAAPGRFAVVMPRVQKLSSFQRVGPATLKPQVQ 1140
Query: 1141 PIQDPKPRACSLRWSCLWLRADAYGPWPRVHTHPQSCHLGPGAACLSLRGSWEEVGPPSW 1200
PIQDPKPRACSLRWSCLWLRADAYGPWPRVHTHPQSCHLGPGAACLSLRGSWEEVGPPSW
Sbjct: 1141 PIQDPKPRACSLRWSCLWLRADAYGPWPRVHTHPQSCHLGPGAACLSLRGSWEEVGPPSW 1200
Query: 1201 RNKMHSIRNLPSMRFREQHGEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILV 1260
RNKMHSIRNLPSMRFREQHGEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILV
Sbjct: 1201 RNKMHSIRNLPSMRFREQHGEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILV 1260
Query: 1261 SVNPYQMFGIYGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSG 1320
SVNPYQMFGIYGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSG
Sbjct: 1261 SVNPYQMFGIYGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSG 1320
Query: 1321 KTEATKLILRYLAAMNQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE 1380
KTEATKLILRYLAAMNQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE
Sbjct: 1321 KTEATKLILRYLAAMNQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE 1380
Query: 1381 GGVISGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQ 1440
GGVISGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQ
Sbjct: 1381 GGVISGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQ 1440
Query: 1441 GGNCEIAGKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEV 1500
GGNCEIAGKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEV
Sbjct: 1441 GGNCEIAGKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEV 1500
Query: 1501 ASVVSAREIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLY 1560
ASVVSAREIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLY
Sbjct: 1501 ASVVSAREIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLY 1560
Query: 1561 ALLFSWLITRVNALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIV 1620
ALLFSWLITRVNALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIV
Sbjct: 1561 ALLFSWLITRVNALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIV 1620
Query: 1621 FQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCH 1680
FQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCH
Sbjct: 1621 FQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCH 1680
Query: 1681 YHHGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA 1740
YHHGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA
Sbjct: 1681 YHHGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA 1740
Query: 1741 HLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNH 1800
HLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNH
Sbjct: 1741 HLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNH 1800
Query: 1801 KKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGD 1860
KKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGD
Sbjct: 1801 KKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGD 1860
Query: 1861 MCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKR 1920
MCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKR
Sbjct: 1861 MCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKR 1920
Query: 1921 RFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVE 1980
RFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVE
Sbjct: 1921 RFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVE 1980
Query: 1981 GALLWEQEELSKREVVAVGHLEVPAELAGLLQAVAGLGLAQVPQVAPVRTPRLQAEPRVT 2040
GALLWEQEELSKREVVAVGHLEVPAELAGLLQAVAGLGLAQVPQVAPVRTPRLQAEPRVT
Sbjct: 1981 GALLWEQEELSKREVVAVGHLEVPAELAGLLQAVAGLGLAQVPQVAPVRTPRLQAEPRVT 2040
Query: 2041 LPLDINNYPMAKFVQCHFKEPAFGMLTVPLRTPLTQLPAEHHAEAVSIFKLILRFMGDPH 2100
LPLDINNYPMAKFVQCHFKEPAFGMLTVPLRTPLTQLPAEHHAEAVSIFKLILRFMGDPH
Sbjct: 2041 LPLDINNYPMAKFVQCHFKEPAFGMLTVPLRTPLTQLPAEHHAEAVSIFKLILRFMGDPH 2100
Query: 2101 LHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAP 2160
LHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAP
Sbjct: 2101 LHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAP 2160
Query: 2161 SPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKA 2220
SPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKA
Sbjct: 2161 SPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKA 2220
Query: 2221 SMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQWAELAGH 2280
SMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQWAELAGH
Sbjct: 2221 SMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQWAELAGH 2280
Query: 2281 DYVLDLVSDLELLRDFPRQKSYFIVGTEGPAASRGGPKVVFGNSWDSDEDMSTRPQPQEH 2340
DYVLDLVSDLELLRDFPRQKSYFIVGTEGPAASRGGPKVVFGNSWDSDEDMSTRPQPQEH
Sbjct: 2281 DYVLDLVSDLELLRDFPRQKSYFIVGTEGPAASRGGPKVVFGNSWDSDEDMSTRPQPQEH 2340
Query: 2341 MPKVLDSDGYSSHNQDGTNGETEAQRGTATHQESDSLGEPAVPHKGLDCYLDSLFDPVLS 2400
MPKVLDSDGYSSHNQDGTNGETEAQRGTATHQESDSLGEPAVPHKGLDCYLDSLFDPVLS
Sbjct: 2341 MPKVLDSDGYSSHNQDGTNGETEAQRGTATHQESDSLGEPAVPHKGLDCYLDSLFDPVLS 2400
Query: 2401 YGDADLEKPTAIAYRMKGGGQPGGGSSSGTEDTPRRPPEPKPIPGLDASTLALQQAFIHK 2460
YGDADLEKPTAIAYRMKGGGQPGGGSSSGTEDTPRRPPEPKPIPGLDASTLALQQAFIHK
Sbjct: 2401 YGDADLEKPTAIAYRMKGGGQPGGGSSSGTEDTPRRPPEPKPIPGLDASTLALQQAFIHK 2460
Query: 2461 QAVLLAREMTLQATALQQQPLSAALRSLPAEKPPAPEAQPTSVGTGPPAKPVLLRATPKP 2520
QAVLLAREMTLQATALQQQPLSAALRSLPAEKPPAPEAQPTSVGTGPPAKPVLLRATPKP
Sbjct: 2461 QAVLLAREMTLQATALQQQPLSAALRSLPAEKPPAPEAQPTSVGTGPPAKPVLLRATPKP 2520
Query: 2521 LAPAPLAKAPRLPIKPVAAPVLAQDQASPETTSPSPELVRYSTLNSEHFPQPTQQIKNIV 2580
LAPAPLAKAPRLPIKPVAAPVLAQDQASPETTSPSPELVRYSTLNSEHFPQPTQQIKNIV
Sbjct: 2521 LAPAPLAKAPRLPIKPVAAPVLAQDQASPETTSPSPELVRYSTLNSEHFPQPTQQIKNIV 2580
Query: 2581 RQYQQPFRGGRPEALRKDGGKVFMKRPDPHEEALMILKGQMTHLAAAPGTQVSREAVALV 2640
RQYQQPFRGGRPEALRKDGGKVFMKRPDPHEEALMILKGQMTHLAAAPGTQVSREAVALV
Sbjct: 2581 RQYQQPFRGGRPEALRKDGGKVFMKRPDPHEEALMILKGQMTHLAAAPGTQVSREAVALV 2640
Query: 2641 KPVTSAPRPSMAPTSALPSRSLEPPEELTQTRLHRLINPNFYGYQDAPWKIFLRKEVFYP 2700
KPVTSAPRPSMAPTSALPSRSLEPPEELTQTRLHRLINPNFYGYQDAPWKIFLRKEVFYP
Sbjct: 2641 KPVTSAPRPSMAPTSALPSRSLEPPEELTQTRLHRLINPNFYGYQDAPWKIFLRKEVFYP 2700
Query: 2701 KDSYSHPVQLDLLFRQILHDTLSEACLRISEDERLRMKALFAQNQLDTQKPLVTESVKRA 2760
KDSYSHPVQLDLLFRQILHDTLSEACLRISEDERLRMKALFAQNQLDTQKPLVTESVKRA
Sbjct: 2701 KDSYSHPVQLDLLFRQILHDTLSEACLRISEDERLRMKALFAQNQLDTQKPLVTESVKRA 2760
Query: 2761 VVSTARDTWEVYFSRIFPATGSVGTGVQLLAVSHVGIKLLRMVKGGQEAGGQLRVLRAYS 2820
VVSTARDTWEVYFSRIFPATGSVGTGVQLLAVSHVGIKLLRMVKGGQEAGGQLRVLRAYS
Sbjct: 2761 VVSTARDTWEVYFSRIFPATGSVGTGVQLLAVSHVGIKLLRMVKGGQEAGGQLRVLRAYS 2820
Query: 2821 FADILFVTMPSQNMLEFNLASEKVILFSARAHQVKTLVDDFILELKKDSDYVVAVRNFLP 2880
FADILFVTMPSQNMLEFNLASEKVILFSARAHQVKTLVDDFILELKKDSDYVVAVRNFLP
Sbjct: 2821 FADILFVTMPSQNMLEFNLASEKVILFSARAHQVKTLVDDFILELKKDSDYVVAVRNFLP 2880
Query: 2881 EDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYLEELRRRGPDFGWRFGTIHGRV 2940
EDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYLEELRRRGPDFGWRFGTIHGRV
Sbjct: 2881 EDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYLEELRRRGPDFGWRFGTIHGRV 2940
Query: 2941 GRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVASAAAAQEVGRRREGPPVRARSADH 3000
GRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVASAAAAQEVGRRREGPPVRARSADH
Sbjct: 2941 GRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVASAAAAQEVGRRREGPPVRARSADH 3000
Query: 3001 GEDALALPPYTMLEFAQKYFRDPQRRPQDGLRLKSKEPRESRTLEDMLCFTKTPLQESLI 3060
GEDALALPPYTMLEFAQKYFRDPQRRPQDGLRLKSKEPRESRTLEDMLCFTKTPLQESLI
Sbjct: 3001 GEDALALPPYTMLEFAQKYFRDPQRRPQDGLRLKSKEPRESRTLEDMLCFTKTPLQESLI 3060
Query: 3061 ELSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLDVLCNLLKLCGDHEVMRDECYCQVVKQ 3120
ELSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLDVLCNLLKLCGDHEVMRDECYCQVVKQ
Sbjct: 3061 ELSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLDVLCNLLKLCGDHEVMRDECYCQVVKQ 3120
Query: 3121 ITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPGLPFQGIAKACEQ 3180
ITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPGLPFQGIAKACEQ
Sbjct: 3121 ITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPGLPFQGIAKACEQ 3180
Query: 3181 NLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVVEEIC 3240
NLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVVEEIC
Sbjct: 3181 NLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVVEEIC 3240
Query: 3241 AEMALTRPEAFNEYVIFVVTNRGQHVCPLSRRAYILDVASEMEQVDGGYMLWFRRVLWDQ 3300
AEMALTRPEAFNEYVIFVVTNRGQHVCPLSRRAYILDVASEMEQVDGGYMLWFRRVLWDQ
Sbjct: 3241 AEMALTRPEAFNEYVIFVVTNRGQHVCPLSRRAYILDVASEMEQVDGGYMLWFRRVLWDQ 3300
Query: 3301 PLKFENELYVTMHYNQVLPDYLKGLFSSVPASRPSEQLLQQVSKLASLQHRAKDHFYLPS 3360
PLKFENELYVTMHYNQVLPDYLKGLFSSVPASRPSEQLLQQVSKLASLQHRAKDHFYLPS
Sbjct: 3301 PLKFENELYVTMHYNQVLPDYLKGLFSSVPASRPSEQLLQQVSKLASLQHRAKDHFYLPS 3360
Query: 3361 VREVQEYIPAQLYRTTAGSTWLNLVSQHRQQTQALSPHQARAQFLGLLSALPMFGSSFFF 3420
VREVQEYIPAQLYRTTAGSTWLNLVSQHRQQTQALSPHQARAQFLGLLSALPMFGSSFFF
Sbjct: 3361 VREVQEYIPAQLYRTTAGSTWLNLVSQHRQQTQALSPHQARAQFLGLLSALPMFGSSFFF 3420
Query: 3421 IQSCSNIAVPAPCILAINHNGLNFLSTETHELMVKFPLKEIQSTRTQRPTANSSYPYVEI 3480
IQSCSNIAVPAPCILAINHNGLNFLSTETHELMVKFPLKEIQSTRTQRPTANSSYPYVEI
Sbjct: 3421 IQSCSNIAVPAPCILAINHNGLNFLSTETHELMVKFPLKEIQSTRTQRPTANSSYPYVEI 3480
Query: 3481 ALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSAHEKRLTLPPSEITLL 3530
ALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSAHEKRLTLPPSEITLL
Sbjct: 3481 ALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSAHEKRLTLPPSEITLL 3530
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 616 bits (1589), Expect = e-175
Identities = 412/1218 (33%), Positives = 626/1218 (51%), Gaps = 166/1218 (13%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
GV+DM +L DL E ++ NL IR++++ IYTY GSILV+VNP+Q+ +Y EQVQ Y R
Sbjct: 66 GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSR 125
Query: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
+GE PPH+FA+AN + M K++QC IISGESG+GKTE TKLIL++LA ++ + +
Sbjct: 126 HMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSWI 185
Query: 1343 QQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE-GGVISGAITSQYLLEKSRIVF 1401
+Q ++LEA P+LE+FGNAKT+RNDNSSRFGK+++I+ GVI GA Q+LLEKSR+
Sbjct: 186 EQ-QVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCR 244
Query: 1402 QAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAA 1461
QA ERNYHIFY +L G+ A+ +Q SL Y+YL G G +DA D+ + +A
Sbjct: 245 QAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSA 304
Query: 1462 MEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPE 1521
M++L FS + + ++LA+ILHLGNV F + + + V+ V +LL++ +
Sbjct: 305 MKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLEVQHQ 364
Query: 1522 GLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV------ 1575
L+ + E + L + A D RDA K +Y LF W++ ++NA +
Sbjct: 365 ELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQ 424
Query: 1576 SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDW 1635
P+ +I +LDI+GFE+ NSFEQLCIN+ANE+LQ F + VF EQEEY E I W
Sbjct: 425 DPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISW 484
Query: 1636 QEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPK-M 1694
I + DN+P ++L++LKP I+ +LD++ FPQ TD T LQK + H N + +PK +
Sbjct: 485 DYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNI 544
Query: 1695 PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQR 1754
F I H+AG+V YQ FL+KN D + D+L L S+ + + +F+ + A +
Sbjct: 545 HDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNL---ELAETK 601
Query: 1755 LG-----KSSSVTRLYKA-------HTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKK 1802
LG ++ + L+K+ T+ ++F+QSL L++ + C P F+RC+KPN K
Sbjct: 602 LGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYK 661
Query: 1803 EPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLV--ALKHDLPANGD 1860
+P LF+ ++ + QLRYSG++ETV IRK GFP+R F+ F R+ L+ A++ L
Sbjct: 662 KPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLR 721
Query: 1861 MCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGF---- 1916
++ + ++ G +K+FL++H LLE R VL+ AAL++Q+ LRG+
Sbjct: 722 QMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRK 781
Query: 1917 -FIK-----------------------------------------RRFRSLRHKIILLQS 1934
F++ R+++++R + + LQ+
Sbjct: 782 EFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQA 841
Query: 1935 RARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRY--LKLRAEWRCQVEGALLWEQEELSK 1992
RGYL RQ+ Q RR++V ++ +RR + K A EG K
Sbjct: 842 LCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVIPAEGQKSQGALPAKK 901
Query: 1993 REVV--AVGHLEVPAELAGLLQAVAGLGLAQVPQVAPVRTPRLQAEPRVTLPLDINNYPM 2050
R + V E+ ++ G L A+ G Q Q +P L+++ + L +D++ PM
Sbjct: 902 RRSIYDTVTDTEMVEKVFGFLPAMIG---GQEGQASP-HFEDLESKTQKLLEVDLDTVPM 957
Query: 2051 A----------------KFVQCHF-KEPAFGMLTVPLRTPLTQLPAEHHA-EAVSIFKLI 2092
A KF +F K + + PLR PL + A+ I+ +I
Sbjct: 958 AEEPEEDVDGLAEYTFPKFAVTYFQKSASHTHIRRPLRYPLLYHEDDTDCLAALVIWNVI 1017
Query: 2093 LRFMGD---PHLHGARENIFGNYIVQK---------GLAVPE------------------ 2122
LRFMGD P L+ AR + G+ ++++ G VP+
Sbjct: 1018 LRFMGDLPEPVLY-ARSSQQGSSVMRQIHDTLGREHGAQVPQHSRSAQVASQLNIGEEAL 1076
Query: 2123 -----------------------------LRDEILAQLANQVWHNHNAHNAERGWLLLAA 2153
LRDEI Q+ Q+ N + RGW+LL+
Sbjct: 1077 EPDGLGADRPMSNLEKVHFIVGYAILRPSLRDEIYCQICKQLSENFKTSSLARGWILLSL 1136
Query: 2154 CLSGFAPSPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEW 2213
CL F PS F KYLL F+ G + C RL + + R PPT LE
Sbjct: 1137 CLGCFPPSERFMKYLLNFIGQ-GPATYGPFCAERLRRTY-------ANGVRAEPPTWLEL 1188
Query: 2214 TATYEKASMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQ 2273
A K + + V G+ + PV S ST E+ I +GL+D
Sbjct: 1189 QAVKSKKHIPIQVILATGESLTVPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKF 1248
Query: 2274 WAELAGHDYVLDLVSDLE 2291
W+ +G D+++D ++ E
Sbjct: 1249 WSLGSGRDHMMDAIARCE 1266
Score = 186 bits (471), Expect = 5e-46
Identities = 218/904 (24%), Positives = 379/904 (41%), Gaps = 144/904 (15%)
Query: 2685 QDAPWKIFLRKEVFYP-KDSYSHPVQLDLLFRQILHDTLSEACLRISEDERLRMKALFAQ 2743
+ +PW+I+ RKE F P DS PV +L++RQ+L S E+E + + A
Sbjct: 1277 RQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYSFEKEEELVELLARHCY 1336
Query: 2744 NQLD------------------------------------------TQKPLVTESVKRAV 2761
QL TQK + +V+ V
Sbjct: 1337 VQLGASAESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAKAPYTQKQVTPLAVREQV 1396
Query: 2762 VSTARDTWEVYFSRIFPATGSVGTGVQ----LLAVSHVGIKLLRMVKGGQEAGGQLRVLR 2817
V AR W + FSR+F G + +LAV+ G+ L Q ++L
Sbjct: 1397 VDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFLDQ---------QEKMLL 1447
Query: 2818 AYSFADILFVTMPSQ----NMLEFNLASEKVILFSARAHQVKTLVDDFILELKKDSDYVV 2873
SF +++ + + L + E+ S + + LV F+ LK+ S + +
Sbjct: 1448 ELSFPEVMGLATNREAQGGQRLLLSTMHEEYEFVSPSSVAIAELVALFLEGLKERSIFAM 1507
Query: 2874 AVRNF-LPEDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYLEELRRRGPDFGWR 2932
A+++ +D LLAF KGD++ L +++ + E W
Sbjct: 1508 ALQDRKATDDTTLLAFKKGDLLVL---------------TKKQGLLASE--------NWT 1544
Query: 2933 FGTIHGRVGRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVASAAAAQEVGRRREGPP 2992
G + R G+ + LV P A + T+P + +A + A + G+ E P
Sbjct: 1545 LGQ-NDRTGK--TGLV-PMACLYTIPTVTKPSAQLLSLLAMSPEKRKLAAQEGQFTEPRP 1600
Query: 2993 VRARSADHGEDALALPPYTMLEFAQKYFRDPQRRPQDGLRLKSKEPRESRTLEDMLCFTK 3052
E+ +T+ EF+ ++FR P++ L +R + ++
Sbjct: 1601 ---------EEPPKEKLHTLEEFSYEFFRAPEKDMVSMAVLPL-----ARARGHLWAYSC 1646
Query: 3053 TPLQESLIEL--SDSSLSKMATDMFLAVMRFMGDAPLK-GQSDLDVLCNLLKLCGDHEVM 3109
PL++ L++ ++ L +A +F+A++R+MGD P + L++ + L H +
Sbjct: 1647 EPLRQPLLKRVHANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTLALQHPAL 1706
Query: 3110 RDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPGL 3169
+DE YCQ++KQ+T N S + S +RGW+LL++ T S+ L PH +F+ +R L
Sbjct: 1707 QDEVYCQILKQLTHN--SNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFID--TRRGKL 1762
Query: 3170 PFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKTC 3229
+A C + +QK LR G R + P +E+ A S P L++
Sbjct: 1763 ----LAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNVSRICHKIYFPNDTSEMLEVVAN 1818
Query: 3230 TVALDVVEEICAEMALTRPEAFNEYVIF---VVTNRGQHVCPLSRRAYILDVASEMEQVD 3286
T DV + I + L E + ++ V++ + S R V Q +
Sbjct: 1819 TRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEGDFFFDSLREVSDWVKKNKPQKE 1878
Query: 3287 GG-----YMLWFRRVLW--DQPLKFENELYVTMHYNQVLPDYLKGLFSSVPASRPSEQLL 3339
G Y ++F R LW P K N + +HY+Q LP YL+G SR
Sbjct: 1879 GAPVTLPYQVYFMRKLWLNISPGKDVNADTI-LHYHQELPKYLRGFHK---CSR------ 1928
Query: 3340 QQVSKLASLQHRAK---DHFYLPSVREV-QEYIPAQLYRTTAGSTWLNLVSQHRQQTQAL 3395
+ LA L ++A+ D L SV ++ +E +P L R + W + + +
Sbjct: 1929 EDAIHLAGLIYKAQFNNDRSQLASVPKILRELVPENLTRLMSSEEWKKSILLAYDKHKDK 1988
Query: 3396 SPHQARAQFLGLLSALPMFGSSFFFIQSCSNIAVPAPCILAINHNGLNFLSTETHELMVK 3455
+ +A+ FL + P FGS+FF ++ S + P ++AIN +G+ + +T +L+
Sbjct: 1989 TVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHPKTKDLLTT 2048
Query: 3456 FPLKEIQSTRTQRPTANSSYPYVEIALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSA 3515
+P +I S +S Y +ALG + L + G ++ ++ +V+ LLSA
Sbjct: 2049 YPFTKISSW-------SSGSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLLSA 2101
Query: 3516 HEKR 3519
K+
Sbjct: 2102 MNKQ 2105
Score = 72.8 bits (177), Expect = 6e-12
Identities = 93/383 (24%), Positives = 166/383 (43%), Gaps = 50/383 (13%)
Query: 3109 MRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPG 3168
+RDE YCQ+ KQ+++N K S RGW LL + SE +L F+ T G
Sbjct: 1106 LRDEIYCQICKQLSEN--FKTSSLARGWILLSLCLGCFPPSERFMKYLLNFIGQGPATYG 1163
Query: 3169 LPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKT 3228
PF C + L++T G R E P+ +EL+A+ + + Q+ L G ++
Sbjct: 1164 -PF------CAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQVILATG--------ES 1208
Query: 3229 CTVALD---VVEEICAEMALTRPEAFNEYVIF--VVTNRGQHVCPLSRRAYILDVASEME 3283
TV +D E+C M + + ++++ F V + S R +++D + E
Sbjct: 1209 LTVPVDSASTSREMC--MHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMDAIARCE 1266
Query: 3284 QVDGGYMLWFRRVLWDQPLKFENELYVTMHYNQVLP--------DYLKGLFSSVPASRPS 3335
Q+ R+ W + F E + H ++ P L+G++S +
Sbjct: 1267 QMAQERGESQRQSPW--RIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYSFEKE 1324
Query: 3336 EQLLQQVSKLASLQHRAKDHFYLPSVREVQEYIPA----QLYRTTAGSTWLNLV----SQ 3387
E+L++ +++ +Q A + VQE +P+ +LYRT W +LV ++
Sbjct: 1325 EELVELLARHCYVQLGAS-----AESKAVQELLPSCIPHKLYRTKPPDRWASLVTAACAK 1379
Query: 3388 HRQQTQALSPHQARAQFLGLLS-ALPMFGSSFFFIQSCSNIAVP-APCILAINHNGLNFL 3445
+ ++P R Q + P+ S F + + S +P ILA+N GL FL
Sbjct: 1380 APYTQKQVTPLAVREQVVDAARLQWPLLFSRLFEVITLSGPRLPKTQLILAVNWKGLCFL 1439
Query: 3446 STETHELMVKFPLKEIQSTRTQR 3468
+ +++++ E+ T R
Sbjct: 1440 D-QQEKMLLELSFPEVMGLATNR 1461
Score = 62.4 bits (150), Expect = 8e-09
Identities = 50/160 (31%), Positives = 66/160 (41%), Gaps = 17/160 (10%)
Query: 2069 PLRTPLTQLPAEHHAE------AVSIFKLILRFMGDPHLHGARENI-FGNYIVQKGLAVP 2121
PLR PL + HA A IF ILR+MGD A + + I L P
Sbjct: 1648 PLRQPLLK---RVHANVDLWDIACQIFVAILRYMGDYPSRQAWPTLELTDQIFTLALQHP 1704
Query: 2122 ELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAPSPCFNKYLLKFVSDYGRNGFQ 2181
L+DE+ Q+ Q+ HN N H+ ERGW LL C F PS + KF+
Sbjct: 1705 ALQDEVYCQILKQLTHNSNRHSEERGWQLLWLCTGLFPPSKGLLPHAQKFIDTRRGKLLA 1764
Query: 2182 AVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKAS 2221
C R+ + + R PP Q+E A + S
Sbjct: 1765 PDCSRRIQKVL-------RTGPRKQPPHQVEVEAAEQNVS 1797
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 594 bits (1532), Expect = e-169
Identities = 339/787 (43%), Positives = 487/787 (61%), Gaps = 28/787 (3%)
Query: 1221 EDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQ-MFGIYGPEQVQQY 1279
E+GV+DM L +L +++ NL R++RN IYTYIGSIL SVNPYQ + G+Y P ++QY
Sbjct: 62 EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY 121
Query: 1280 NGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKR 1339
+ R LGE PPH+FA+AN + + NQCI+ISGESG+GKTE+TKLIL++L+ ++Q+
Sbjct: 122 SRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQS 181
Query: 1340 EVMQ--------QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFL-EGGVISGAITS 1390
+ + ILE++P++E+FGNAKTV N+NSSRFGKFV++ + + G I G
Sbjct: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
Query: 1391 QYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKS 1450
YLLEK+R+V Q ERNYHIFY LLAGL + R+ F L E Y+YLNQ G E S
Sbjct: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTIS 301
Query: 1451 DADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQ 1510
D + FR ++ AM+V+ FS E+ + R+LA ILHLGN+ F A V +
Sbjct: 302 DQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFI-----TAGGAQVSFKTALG 356
Query: 1511 AVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITR 1570
AELL + P L A+T + E+I TPL V+ AVD+RD++A LYA F W+I +
Sbjct: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
Query: 1571 VNALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIR 1630
+N+ + +D SI ILDI+GFE+ N FEQ INYANE LQ FNK +F EQ EY R
Sbjct: 417 INSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSR 476
Query: 1631 EQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYS 1690
E + W++I + DN C++LI K G+L +++++ FPQATD T L+K H H N Y
Sbjct: 477 EGLVWEDIDWIDNGECLDLIE-KKLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYV 535
Query: 1691 KPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQA 1750
KP++ + F +KHYAG+V Y V L+KN D R D+L+L SR + LF H
Sbjct: 536 KPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFE-HVSSR 594
Query: 1751 APQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPD 1810
Q K S ++ TV+++F+ SL L+ + NP F+RC+KPN +K P F+
Sbjct: 595 NNQDTLKCGSK---HRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQA 651
Query: 1811 VVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLV---ALKHDLPANGDMCVSVLS 1867
VV+ QLRYSG+LETVRIRK G+ VR PFQ F RY L+ AL D+ C S+L
Sbjct: 652 VVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGK---CTSLL- 707
Query: 1868 RLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRH 1927
+L + +++G +K+FL+E L Q LE RE ++ AA+ ++ + GF ++++R + +
Sbjct: 708 QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY 767
Query: 1928 KIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVEGALLWEQ 1987
++++Q R +L R+R+ ++++ + F+ + ++RR Y +L AE R Q E E+
Sbjct: 768 CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQ-EEKKKQEE 826
Query: 1988 EELSKRE 1994
EE KRE
Sbjct: 827 EEKKKRE 833
Score = 46.6 bits (109), Expect = 4e-04
Identities = 76/337 (22%), Positives = 139/337 (41%), Gaps = 33/337 (9%)
Query: 3047 MLCFTKTPLQESLIEL--SDSSLSKMATDMFL-----AVMRFMGDAPLKGQSD-LDVLCN 3098
+L +T PL L+ L D +L+ + + A+ F L+ SD + ++
Sbjct: 1532 ILRYTHHPLHSPLLPLPYGDINLNLLKDKGYTTLQDEAIKIFNSLQQLESMSDPIPIIQG 1591
Query: 3099 LLKLCGDHEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTR 3158
+L+ D +RDE YCQ++KQ W++L ++ S + +L
Sbjct: 1592 ILQTGHDLRPLRDELYCQLIKQTNKVPHPGSVGNLYSWQILTCLSCTFLPSRGILKYLKF 1651
Query: 3159 FLQDV-SRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLP 3217
L+ + + PG + A ++L+KT R +PS E+ A++ R
Sbjct: 1652 HLKRIREQFPGSEMEKYALFTYESLKKT---KCREFVPSRDEIEALI-HRQEMTSTVYCH 1707
Query: 3218 GGLERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFVVTNRGQHVCPLSRRAYILD 3277
GG + I + T A +VVE++ +A+ ++ N + +F G + R + D
Sbjct: 1708 GGGSCKITINSHTTAGEVVEKLIRGLAM--EDSRNMFALF--EYNGHVDKAIESRTVVAD 1763
Query: 3278 VASEMEQVDGGYMLWFRRVLWDQPLKFENELYVTMHYNQVLPDYLKGLF-------SSVP 3330
V ++ E+ L + D P KF +LY + + V D ++ F + +
Sbjct: 1764 VLAKFEK------LAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIH 1817
Query: 3331 ASRPSEQLLQQVSKLASLQHRAKD---HFYLPSVREV 3364
P+ + QV LQ+ D H +P + EV
Sbjct: 1818 GHHPAPEENLQVLAALRLQYLQGDYTLHAAIPPLEEV 1854
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 573 bits (1477), Expect = e-162
Identities = 357/1007 (35%), Positives = 542/1007 (53%), Gaps = 137/1007 (13%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
GVEDM +L DL E +L NL IR+ +LIYTY GSILV+VNPYQ+ IY PE ++QY +
Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
Query: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
+GE PPH+FA+A+ + M ++QC IISGESG+GKTE+TKLIL++LAA++ + +
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWI 185
Query: 1343 QQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVF 1401
+Q ++LEATP+LE+FGNAKT+RNDNSSRFGK+++I F + G I GA QYLLEKSR+
Sbjct: 186 EQ-QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
Query: 1402 QAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAA 1461
QA +ERNYH+FY +L G+ ++ L +A Y YL G G+ D+ ++ + +A
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
Query: 1462 MEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPE 1521
M+VL F+ + I ++LA+ILHLGN+ +E + + V+ + + A LL+++P
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPP 364
Query: 1522 GLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV--SPRQ 1579
L +T + T E + TPL+ E A+D RDA K +Y LF W++ ++NA + P Q
Sbjct: 365 DLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQ 424
Query: 1580 DT----LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDW 1635
D SI +LDI+GFE+ + NSFEQLCIN+ANE+LQ F + VF+ EQEEY E IDW
Sbjct: 425 DVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDW 484
Query: 1636 QEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPK-M 1694
I F DNQ +++I+ KP I+ ++D++ FP+ TD T L K + H N Y PK
Sbjct: 485 LHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNN 544
Query: 1695 PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQR 1754
+F I H+AG V Y+ FL+KN D + D++ L SR + + +F + A R
Sbjct: 545 HETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETR 604
Query: 1755 LGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMA 1814
++ T++++F++SL L+ + C P F+RC+KPN K+P LF+ + +
Sbjct: 605 ----------KRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVR 654
Query: 1815 QLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRLCKVM- 1873
QLRYSG++ET+RIR+ G+P+R F F++RY L+ GD+ R+ + +
Sbjct: 655 QLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDL-RGTCQRMAEAVL 713
Query: 1874 --PNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGF-----FIK------- 1919
+ +++G +K+FLK+H LLE R+ + + LQ+ +RGF F+K
Sbjct: 714 GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATL 773
Query: 1920 ----------------------------------RRFRSLRHKIILLQSRARGYLARQRY 1945
+++R R +II Q+R R YL R+ +
Sbjct: 774 IQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAF 833
Query: 1946 QQMRRSLVKFRSLVHAYVSRRRYLKLRAE--WRCQVEGALLWEQEELSK----------- 1992
+ +++ ++ ++RR + +LRAE WR + E L E+E+L K
Sbjct: 834 RHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEA 893
Query: 1993 -----------------REV---------------------VAVGHLEVPAELAGLLQAV 2014
RE+ V H ++ ++ G L
Sbjct: 894 ERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTS 953
Query: 2015 AGL--GLAQVP----QVAPVRTPRLQAEPRVTLPL------DINNYPMAKFVQCHFKEPA 2062
GL Q P + R ++ + LPL D++ Y AKF +F+
Sbjct: 954 GGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTT 1013
Query: 2063 FGMLT-VPLRTPLTQLPAE-HHAEAVSIFKLILRFMGD---PHLHGA 2104
T PL+ PL E A++++ ILRFMGD P H A
Sbjct: 1014 THSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTA 1060
Score = 203 bits (517), Expect = 2e-51
Identities = 231/923 (25%), Positives = 390/923 (42%), Gaps = 180/923 (19%)
Query: 2685 QDAPWKIFLRKEVFYPKDSYSHP-VQLDLLFRQILH------------DTLSE-ACLRIS 2730
++APW++F RKEVF P S S V +L+++Q++ D L+E A +
Sbjct: 1338 RNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEYRCEKEDDLAELASQQYF 1397
Query: 2731 ED-------ERL-----------------------------RMKALFAQNQLDTQKPLVT 2754
D ERL K ++AQ + D QK
Sbjct: 1398 VDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHKKGIYAQRRTDAQK---- 1453
Query: 2755 ESVKRAVVSTARDTWEVYFSRIFPATGSVGTGVQ----LLAVSHVGIKLLRMVKGGQEAG 2810
VK VVS AR W + FSR + A G + ++AV+ G+ +
Sbjct: 1454 --VKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYFV---------D 1502
Query: 2811 GQLRVLRAYSFADILFV--------TMPSQNMLEFNLASEKVILFSARAHQVKTLVDDFI 2862
Q +VL SF +I+ V T PS + + ++ S+ A ++ LV F+
Sbjct: 1503 EQEQVLLELSFPEIMAVSSSRGAKTTAPSFTLA--TIKGDEYTFTSSNAEDIRDLVVTFL 1560
Query: 2863 LELKKDSDYVVAVR---NFLPEDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYL 2919
L+K S YVVA++ N E+ L+F KGD+I L +V S
Sbjct: 1561 EGLRKRSKYVVALQDNPNPAGEESGFLSFAKGDLIILDHDTGEQVMNS------------ 1608
Query: 2920 EELRRRGPDFGWRFGTIHGRV---GRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVA 2976
GW G I+ R G FP++ V P P E VA
Sbjct: 1609 ----------GWANG-INERTKQRGDFPTDSVY--VMPTVTMPPRE-------IVALVTM 1648
Query: 2977 SAAAAQEVGR----RREGPPVRARSADHGEDALALPPYTMLEFAQKYFRDPQRRPQDGLR 3032
+ Q+V R R P VRA+ PYT+ EF+ YFR P + +
Sbjct: 1649 TPDQRQDVVRLLQLRTAEPEVRAK------------PYTLEEFSYDYFRPPPKHTLSRVM 1696
Query: 3033 LKSKEPRESRTLEDMLCFTKTPLQESLIE--LSDSSLSKMATDMFLAVMRFMGDAPLKGQ 3090
+ ++R + + T+ PL+++L++ L LS+ A F+AV+++MGD P K
Sbjct: 1697 VS-----KARGKDRLWSHTREPLKQALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRT 1751
Query: 3091 SDLDVLCN-LLKLCGDHEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCS 3149
++ L + + + E ++DE Y Q++KQ+TDN + +RGW LL++ T S
Sbjct: 1752 RSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRYSE--ERGWELLWLCTGLFPPS 1809
Query: 3150 EVLHPHLTRFLQDVSRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSS 3209
+L PH+ RFLQ P +A C Q LQK LR G R P +E+ A+ +
Sbjct: 1810 NILLPHVQRFLQSRKHCP------LAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQ 1863
Query: 3210 KRQLFLLPGGLERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFV--VTNRGQHVC 3267
P + ++++ T A D + I + L E F+ +V V + ++
Sbjct: 1864 IFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDF 1923
Query: 3268 PLSRRAYILDVASEMEQVDGG------YMLWFRRVLWDQPLKFENELYVTM-HYNQVLPD 3320
++ D + + G Y ++F + LW + ++ + ++ HY Q LP
Sbjct: 1924 FFDFVRHLTDWIKKARPIKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPK 1983
Query: 3321 YLKGLFSSVPASRPSEQLLQQVSKLASLQHRAK---DHFYLPSV-REVQEYIPAQLYRTT 3376
YL+G ++V +L +L +R K D Y PS+ + ++E +P L R
Sbjct: 1984 YLRGYHKCT---------REEVLQLGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQV 2034
Query: 3377 AGSTWLNLVSQHRQQTQALSPHQARAQFLGLLSALPMFGSSFFFIQSCSNIAVPAPCILA 3436
+ W + + + S +A+ FL L+ P FGS+FF + + P ++A
Sbjct: 2035 SPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFF--EQTTEPNFPEILLIA 2092
Query: 3437 INHNGLNFLSTETHELMVKFPLKEIQSTRTQRPTANSSYPYVEIALGDVAAQRTLQLQLE 3496
IN G++ + +T +++ P +I + +S Y I +G++ L +
Sbjct: 2093 INKYGVSLIDPKTKDILTTHPFTKISNW-------SSGNTYFHITIGNLVRGSKLLCETS 2145
Query: 3497 QGLELCRVVAVHVENLLSAHEKR 3519
G ++ ++ ++ +L+A K+
Sbjct: 2146 LGYKMDDLLTSYISQMLTAMSKQ 2168
Score = 82.4 bits (202), Expect = 7e-15
Identities = 56/182 (30%), Positives = 92/182 (50%), Gaps = 10/182 (5%)
Query: 2111 NYIVQKGLAVPELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAPSPCFNKYLLK 2170
++I+ G+ P LRDEI Q++ Q+ HN + + RGW+L++ C+ FAPS F KYL
Sbjct: 1155 HFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVGCFAPSEKFVKYLRN 1214
Query: 2171 FVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKASMALDVGCFN 2230
F+ G G+ C+ RL + RT PP+ LE AT K + L V +
Sbjct: 1215 FIHG-GPPGYAPYCEERLRRTF-------VNGTRTQPPSWLELQATKSKKPIMLPVTFMD 1266
Query: 2231 GDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQWAEL-AGHDYVLDLVSD 2289
G + S +T +E+ + L D + G+++ + + + L +G D+V+D +S
Sbjct: 1267 GTTKTLLTDSATTAKELCNALADKISLKDRF-GFSLYIALFDKVSSLGSGSDHVMDAISQ 1325
Query: 2290 LE 2291
E
Sbjct: 1326 CE 1327
Score = 65.1 bits (157), Expect = 1e-09
Identities = 108/459 (23%), Positives = 197/459 (42%), Gaps = 68/459 (14%)
Query: 3052 KTPLQESLIELSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLD--VLCNLLKL---CGD- 3105
K+ ++ L+ L+ SK+ ++ + G++ ++G S L+ NL KL G+
Sbjct: 1104 KSSVRHKLVHLTLKKKSKLTEEVTKRLHD--GESTVQGNSMLEDRPTSNLEKLHFIIGNG 1161
Query: 3106 --HEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDV 3163
+RDE YCQ+ KQ+T N S + S RGW L+ + + SE +L F+
Sbjct: 1162 ILRPALRDEIYCQISKQLTHNPS--KSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHG- 1218
Query: 3164 SRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFL---LPGGL 3220
G P G A CE+ L++T G R + PS +EL+A SK+ + L G
Sbjct: 1219 ----GPP--GYAPYCEERLRRTFVNGTRTQPPSWLELQA----TKSKKPIMLPVTFMDGT 1268
Query: 3221 ERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFV--VTNRGQHVCPLSRRAYILDV 3278
+ L + T A ++ + +++L F+ Y+ V++ G S +++D
Sbjct: 1269 TKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLG------SGSDHVMDA 1322
Query: 3279 ASEMEQV---------DGGYMLWFRRVL---WDQPLKFENELYVTMHYNQVLPDYLKGLF 3326
S+ EQ + + L+FR+ + W P E+ + + Y QV+ G +
Sbjct: 1323 ISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSP--SEDNVATNLIYQQVVRGVKFGEY 1380
Query: 3327 SSVPASRPSEQLLQQVSKLASLQH---RAKDHFYLPSVREVQEYIP-AQLYRTTAGSTWL 3382
+ +++LAS Q+ + + V YIP ++ W
Sbjct: 1381 RC--------EKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWA 1432
Query: 3383 NL-VSQHRQQTQALSPHQARAQFLGLLS----ALPMFGSSFFFIQSCSNIAVPA-PCILA 3436
L ++ H++ A A+ ++S P+ S F+ S ++P I+A
Sbjct: 1433 QLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVA 1492
Query: 3437 INHNGLNFLSTETHELM-VKFP-LKEIQSTRTQRPTANS 3473
+N G+ F+ + L+ + FP + + S+R + TA S
Sbjct: 1493 VNWTGVYFVDEQEQVLLELSFPEIMAVSSSRGAKTTAPS 1531
Score = 53.9 bits (128), Expect = 3e-06
Identities = 51/208 (24%), Positives = 80/208 (38%), Gaps = 8/208 (3%)
Query: 2084 EAVSIFKLILRFMGD-PHLHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHNHNAH 2142
EA F +L++MGD P N + I + L L+DE Q+ Q+ NH +
Sbjct: 1731 EACLAFIAVLKYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRY 1790
Query: 2143 NAERGWLLLAACLSGFAPSPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGA 2202
+ ERGW LL C F PS ++ +F+ C RL +A+
Sbjct: 1791 SEERGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKAL-------RNG 1843
Query: 2203 ARTLPPTQLEWTATYEKASMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWR 2262
+R PP +E A K + F D ST + + R L
Sbjct: 1844 SRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSE 1903
Query: 2263 GWTVAMKNGVQWAELAGHDYVLDLVSDL 2290
G+++ +K + + +D+ D V L
Sbjct: 1904 GFSLFVKIADKVLSVPENDFFFDFVRHL 1931
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 573 bits (1477), Expect = e-162
Identities = 357/1007 (35%), Positives = 542/1007 (53%), Gaps = 137/1007 (13%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
GVEDM +L DL E +L NL IR+ +LIYTY GSILV+VNPYQ+ IY PE ++QY +
Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
Query: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
+GE PPH+FA+A+ + M ++QC IISGESG+GKTE+TKLIL++LAA++ + +
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWI 185
Query: 1343 QQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVF 1401
+Q ++LEATP+LE+FGNAKT+RNDNSSRFGK+++I F + G I GA QYLLEKSR+
Sbjct: 186 EQ-QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
Query: 1402 QAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAA 1461
QA +ERNYH+FY +L G+ ++ L +A Y YL G G+ D+ ++ + +A
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
Query: 1462 MEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPE 1521
M+VL F+ + I ++LA+ILHLGN+ +E + + V+ + + A LL+++P
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPP 364
Query: 1522 GLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV--SPRQ 1579
L +T + T E + TPL+ E A+D RDA K +Y LF W++ ++NA + P Q
Sbjct: 365 DLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQ 424
Query: 1580 DT----LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDW 1635
D SI +LDI+GFE+ + NSFEQLCIN+ANE+LQ F + VF+ EQEEY E IDW
Sbjct: 425 DVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDW 484
Query: 1636 QEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPK-M 1694
I F DNQ +++I+ KP I+ ++D++ FP+ TD T L K + H N Y PK
Sbjct: 485 LHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNN 544
Query: 1695 PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQR 1754
+F I H+AG V Y+ FL+KN D + D++ L SR + + +F + A R
Sbjct: 545 HETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETR 604
Query: 1755 LGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMA 1814
++ T++++F++SL L+ + C P F+RC+KPN K+P LF+ + +
Sbjct: 605 ----------KRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVR 654
Query: 1815 QLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRLCKVM- 1873
QLRYSG++ET+RIR+ G+P+R F F++RY L+ GD+ R+ + +
Sbjct: 655 QLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDL-RGTCQRMAEAVL 713
Query: 1874 --PNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGF-----FIK------- 1919
+ +++G +K+FLK+H LLE R+ + + LQ+ +RGF F+K
Sbjct: 714 GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATL 773
Query: 1920 ----------------------------------RRFRSLRHKIILLQSRARGYLARQRY 1945
+++R R +II Q+R R YL R+ +
Sbjct: 774 IQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAF 833
Query: 1946 QQMRRSLVKFRSLVHAYVSRRRYLKLRAE--WRCQVEGALLWEQEELSK----------- 1992
+ +++ ++ ++RR + +LRAE WR + E L E+E+L K
Sbjct: 834 RHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEA 893
Query: 1993 -----------------REV---------------------VAVGHLEVPAELAGLLQAV 2014
RE+ V H ++ ++ G L
Sbjct: 894 ERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTS 953
Query: 2015 AGL--GLAQVP----QVAPVRTPRLQAEPRVTLPL------DINNYPMAKFVQCHFKEPA 2062
GL Q P + R ++ + LPL D++ Y AKF +F+
Sbjct: 954 GGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTT 1013
Query: 2063 FGMLT-VPLRTPLTQLPAE-HHAEAVSIFKLILRFMGD---PHLHGA 2104
T PL+ PL E A++++ ILRFMGD P H A
Sbjct: 1014 THSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTA 1060
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 573 bits (1477), Expect = e-162
Identities = 357/1007 (35%), Positives = 542/1007 (53%), Gaps = 137/1007 (13%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
GVEDM +L DL E +L NL IR+ +LIYTY GSILV+VNPYQ+ IY PE ++QY +
Sbjct: 66 GVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNK 125
Query: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
+GE PPH+FA+A+ + M ++QC IISGESG+GKTE+TKLIL++LAA++ + +
Sbjct: 126 KIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWI 185
Query: 1343 QQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVF 1401
+Q ++LEATP+LE+FGNAKT+RNDNSSRFGK+++I F + G I GA QYLLEKSR+
Sbjct: 186 EQ-QVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
Query: 1402 QAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAA 1461
QA +ERNYH+FY +L G+ ++ L +A Y YL G G+ D+ ++ + +A
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
Query: 1462 MEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPE 1521
M+VL F+ + I ++LA+ILHLGN+ +E + + V+ + + A LL+++P
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPP 364
Query: 1522 GLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV--SPRQ 1579
L +T + T E + TPL+ E A+D RDA K +Y LF W++ ++NA + P Q
Sbjct: 365 DLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQ 424
Query: 1580 DT----LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDW 1635
D SI +LDI+GFE+ + NSFEQLCIN+ANE+LQ F + VF+ EQEEY E IDW
Sbjct: 425 DVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDW 484
Query: 1636 QEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPK-M 1694
I F DNQ +++I+ KP I+ ++D++ FP+ TD T L K + H N Y PK
Sbjct: 485 LHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNN 544
Query: 1695 PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQR 1754
+F I H+AG V Y+ FL+KN D + D++ L SR + + +F + A R
Sbjct: 545 HETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETR 604
Query: 1755 LGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMA 1814
++ T++++F++SL L+ + C P F+RC+KPN K+P LF+ + +
Sbjct: 605 ----------KRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVR 654
Query: 1815 QLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRLCKVM- 1873
QLRYSG++ET+RIR+ G+P+R F F++RY L+ GD+ R+ + +
Sbjct: 655 QLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDL-RGTCQRMAEAVL 713
Query: 1874 --PNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGF-----FIK------- 1919
+ +++G +K+FLK+H LLE R+ + + LQ+ +RGF F+K
Sbjct: 714 GTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATL 773
Query: 1920 ----------------------------------RRFRSLRHKIILLQSRARGYLARQRY 1945
+++R R +II Q+R R YL R+ +
Sbjct: 774 IQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAF 833
Query: 1946 QQMRRSLVKFRSLVHAYVSRRRYLKLRAE--WRCQVEGALLWEQEELSK----------- 1992
+ +++ ++ ++RR + +LRAE WR + E L E+E+L K
Sbjct: 834 RHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEA 893
Query: 1993 -----------------REV---------------------VAVGHLEVPAELAGLLQAV 2014
RE+ V H ++ ++ G L
Sbjct: 894 ERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTS 953
Query: 2015 AGL--GLAQVP----QVAPVRTPRLQAEPRVTLPL------DINNYPMAKFVQCHFKEPA 2062
GL Q P + R ++ + LPL D++ Y AKF +F+
Sbjct: 954 GGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDEEDLSEYKFAKFAATYFQGTT 1013
Query: 2063 FGMLT-VPLRTPLTQLPAE-HHAEAVSIFKLILRFMGD---PHLHGA 2104
T PL+ PL E A++++ ILRFMGD P H A
Sbjct: 1014 THSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTA 1060
Score = 194 bits (493), Expect = 1e-48
Identities = 229/959 (23%), Positives = 393/959 (40%), Gaps = 212/959 (22%)
Query: 2685 QDAPWKIFLRKEVFYPKDSYSHP-VQLDLLFRQILH------------DTLSE-ACLRIS 2730
++APW++F RKEVF P S S V +L+++Q++ D L+E A +
Sbjct: 1338 RNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEYRCEKEDDLAELASQQYF 1397
Query: 2731 ED-------ERL-----------------------------RMKALFAQNQLDTQKPLVT 2754
D ERL K ++AQ + D QK
Sbjct: 1398 VDYGSEMILERLLNLVPTYIPDREITPLKTLEKWAQLAIAAHKKGIYAQRRTDAQK---- 1453
Query: 2755 ESVKRAVVSTARDTWEVYFSRIFPATGSVGTGVQ----LLAVSHVGIKLLRMVKGGQEAG 2810
VK VVS AR W + FSR + A G + ++AV+ G+ +
Sbjct: 1454 --VKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVAVNWTGVYFV---------D 1502
Query: 2811 GQLRVLRAYSFADILFVTMPSQNML----------------------------------- 2835
Q +VL SF +I+ V+ + +
Sbjct: 1503 EQEQVLLELSFPEIMAVSSSRECRVWLSLGCSDLGCAAPHSGWAGLTPAGPCSPCWSCRG 1562
Query: 2836 ------EFNLAS---EKVILFSARAHQVKTLVDDFILELKKDSDYVVAVR---NFLPEDP 2883
F LA+ ++ S+ A ++ LV F+ L+K S YVVA++ N E+
Sbjct: 1563 AKTTAPSFTLATIKGDEYTFTSSNAEDIRDLVVTFLEGLRKRSKYVVALQDNPNPAGEES 1622
Query: 2884 ALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYLEELRRRGPDFGWRFGTIHGRV--- 2940
L+F KGD+I L + + + GW G I+ R
Sbjct: 1623 GFLSFAKGDLIILD----------------------HDTGEQVMNSGWANG-INERTKQR 1659
Query: 2941 GRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVASAAAAQEVGR----RREGPPVRAR 2996
G FP++ V P P E VA + Q+V R R P VRA+
Sbjct: 1660 GDFPTDSVY--VMPTVTMPPRE-------IVALVTMTPDQRQDVVRLLQLRTAEPEVRAK 1710
Query: 2997 SADHGEDALALPPYTMLEFAQKYFRDPQRRPQDGLRLKSKEPRESRTLEDMLCFTKTPLQ 3056
PYT+ EF+ YFR P + + + ++R + + T+ PL+
Sbjct: 1711 ------------PYTLEEFSYDYFRPPPKHTLSRVMVS-----KARGKDRLWSHTREPLK 1753
Query: 3057 ESLIE--LSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLDVLCN-LLKLCGDHEVMRDEC 3113
++L++ L LS+ A F+AV+++MGD P K ++ L + + + E ++DE
Sbjct: 1754 QALLKKLLGSEELSQEACLAFIAVLKYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEA 1813
Query: 3114 YCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPGLPFQG 3173
Y Q++KQ+TDN + +RGW LL++ T S +L PH+ RFLQ P
Sbjct: 1814 YVQILKQLTDNHIRYSE--ERGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCP------ 1865
Query: 3174 IAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVAL 3233
+A C Q LQK LR G R P +E+ A+ + P + ++++ T A
Sbjct: 1866 LAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAK 1925
Query: 3234 DVVEEICAEMALTRPEAFNEYVIFV--VTNRGQHVCPLSRRAYILDVASEMEQVDGG--- 3288
D + I + L E F+ +V V + ++ ++ D + + G
Sbjct: 1926 DFCQNIATRLLLKSSEGFSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARPIKDGIVP 1985
Query: 3289 ---YMLWFRRVLWDQPLKFENELYVTM-HYNQVLPDYLKGLFSSVPASRPSEQLLQQVSK 3344
Y ++F + LW + ++ + ++ HY Q LP YL+G ++V +
Sbjct: 1986 SLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCT---------REEVLQ 2036
Query: 3345 LASLQHRAK---DHFYLPSV-REVQEYIPAQLYRTTAGSTWLNLVSQHRQQTQALSPHQA 3400
L +L +R K D Y PS+ + ++E +P L R + W + + + S +A
Sbjct: 2037 LGALIYRVKFEEDKSYFPSIPKLLRELVPQDLIRQVSPDDWKRSIVAYFNKHAGKSKEEA 2096
Query: 3401 RAQFLGLLSALPMFGSSFFFIQSCSNIAVPAPCILAINHNGLNFLSTETHELMVKFPLKE 3460
+ FL L+ P FGS+FF ++ + P ++AIN G++ + +T +++ P +
Sbjct: 2097 KLAFLKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTK 2156
Query: 3461 IQSTRTQRPTANSSYPYVEIALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSAHEKR 3519
I + +S Y I +G++ L + G ++ ++ ++ +L+A K+
Sbjct: 2157 ISNW-------SSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQ 2208
Score = 82.4 bits (202), Expect = 7e-15
Identities = 56/182 (30%), Positives = 92/182 (50%), Gaps = 10/182 (5%)
Query: 2111 NYIVQKGLAVPELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAPSPCFNKYLLK 2170
++I+ G+ P LRDEI Q++ Q+ HN + + RGW+L++ C+ FAPS F KYL
Sbjct: 1155 HFIIGNGILRPALRDEIYCQISKQLTHNPSKSSYARGWILVSLCVGCFAPSEKFVKYLRN 1214
Query: 2171 FVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKASMALDVGCFN 2230
F+ G G+ C+ RL + RT PP+ LE AT K + L V +
Sbjct: 1215 FIHG-GPPGYAPYCEERLRRTF-------VNGTRTQPPSWLELQATKSKKPIMLPVTFMD 1266
Query: 2231 GDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQWAEL-AGHDYVLDLVSD 2289
G + S +T +E+ + L D + G+++ + + + L +G D+V+D +S
Sbjct: 1267 GTTKTLLTDSATTAKELCNALADKISLKDRF-GFSLYIALFDKVSSLGSGSDHVMDAISQ 1325
Query: 2290 LE 2291
E
Sbjct: 1326 CE 1327
Score = 63.5 bits (153), Expect = 3e-09
Identities = 104/452 (23%), Positives = 193/452 (42%), Gaps = 67/452 (14%)
Query: 3052 KTPLQESLIELSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLD--VLCNLLKL---CGD- 3105
K+ ++ L+ L+ SK+ ++ + G++ ++G S L+ NL KL G+
Sbjct: 1104 KSSVRHKLVHLTLKKKSKLTEEVTKRLHD--GESTVQGNSMLEDRPTSNLEKLHFIIGNG 1161
Query: 3106 --HEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDV 3163
+RDE YCQ+ KQ+T N S + S RGW L+ + + SE +L F+
Sbjct: 1162 ILRPALRDEIYCQISKQLTHNPS--KSSYARGWILVSLCVGCFAPSEKFVKYLRNFIHG- 1218
Query: 3164 SRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFL---LPGGL 3220
G P G A CE+ L++T G R + PS +EL+A SK+ + L G
Sbjct: 1219 ----GPP--GYAPYCEERLRRTFVNGTRTQPPSWLELQA----TKSKKPIMLPVTFMDGT 1268
Query: 3221 ERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFV--VTNRGQHVCPLSRRAYILDV 3278
+ L + T A ++ + +++L F+ Y+ V++ G S +++D
Sbjct: 1269 TKTLLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLG------SGSDHVMDA 1322
Query: 3279 ASEMEQV---------DGGYMLWFRRVL---WDQPLKFENELYVTMHYNQVLPDYLKGLF 3326
S+ EQ + + L+FR+ + W P E+ + + Y QV+ G +
Sbjct: 1323 ISQCEQYAKEQGAQERNAPWRLFFRKEVFTPWHSP--SEDNVATNLIYQQVVRGVKFGEY 1380
Query: 3327 SSVPASRPSEQLLQQVSKLASLQH---RAKDHFYLPSVREVQEYIP-AQLYRTTAGSTWL 3382
+ +++LAS Q+ + + V YIP ++ W
Sbjct: 1381 RC--------EKEDDLAELASQQYFVDYGSEMILERLLNLVPTYIPDREITPLKTLEKWA 1432
Query: 3383 NL-VSQHRQQTQALSPHQARAQFLGLLS----ALPMFGSSFFFIQSCSNIAVPA-PCILA 3436
L ++ H++ A A+ ++S P+ S F+ S ++P I+A
Sbjct: 1433 QLAIAAHKKGIYAQRRTDAQKVKEDVVSYARFKWPLLFSRFYEAYKFSGPSLPKNDVIVA 1492
Query: 3437 INHNGLNFLSTETHELMVKFPLKEIQSTRTQR 3468
+N G+ F+ E +++++ EI + + R
Sbjct: 1493 VNWTGVYFVD-EQEQVLLELSFPEIMAVSSSR 1523
Score = 53.9 bits (128), Expect = 3e-06
Identities = 51/208 (24%), Positives = 80/208 (38%), Gaps = 8/208 (3%)
Query: 2084 EAVSIFKLILRFMGD-PHLHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHNHNAH 2142
EA F +L++MGD P N + I + L L+DE Q+ Q+ NH +
Sbjct: 1769 EACLAFIAVLKYMGDYPSKRTRSVNELTDQIFEGPLKAEPLKDEAYVQILKQLTDNHIRY 1828
Query: 2143 NAERGWLLLAACLSGFAPSPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGA 2202
+ ERGW LL C F PS ++ +F+ C RL +A+
Sbjct: 1829 SEERGWELLWLCTGLFPPSNILLPHVQRFLQSRKHCPLAIDCLQRLQKAL-------RNG 1881
Query: 2203 ARTLPPTQLEWTATYEKASMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWR 2262
+R PP +E A K + F D ST + + R L
Sbjct: 1882 SRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVESSTKAKDFCQNIATRLLLKSSE 1941
Query: 2263 GWTVAMKNGVQWAELAGHDYVLDLVSDL 2290
G+++ +K + + +D+ D V L
Sbjct: 1942 GFSLFVKIADKVLSVPENDFFFDFVRHL 1969
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 512 bits (1319), Expect = e-144
Identities = 310/797 (38%), Positives = 445/797 (55%), Gaps = 50/797 (6%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRF-ERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281
G D+T L L E VL NLK+RF E N IYTY G +LV++NPY+ IYG + + Y+G
Sbjct: 70 GENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSG 129
Query: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMN-QKRE 1340
+ +G+ PH+FAVA A+ +M ++NQ II+SGESG+GKT + K +RY A + E
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASE 189
Query: 1341 VMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399
+ K+L ++P++E+ GNAKT RNDNSSRFGK+++I F + I GA YLLEKSR+
Sbjct: 190 TNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRV 249
Query: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459
VFQA +ERNYHIFY+L A + +L AE ++Y +QGG+ I G DA+DF +
Sbjct: 250 VFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTR 309
Query: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQIS 1519
A +LG Q SIF+I+ASILHLG+V + E D + + LL +
Sbjct: 310 QAFTLLGVKESHQMSIFKIIASILHLGSVAIQA-ERDGDSCSISPQDVYLSNFCRLLGVE 368
Query: 1520 PEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVN-ALVSPR 1578
++ + + T E ++++ ++AR+A+AK +YA LF W++ +N AL +
Sbjct: 369 HSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSL 428
Query: 1579 QDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQEI 1638
+ I +LDIYGFE NSFEQ CINYANE LQ FN VF+ EQEEY++EQI W I
Sbjct: 429 KQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLI 488
Query: 1639 TFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPKMPLPE 1698
F DNQPCI+LI K GIL +LD++C P+ TD + QK + H ++ + KP+M
Sbjct: 489 DFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPRMSNTA 547
Query: 1699 FTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQRLGKS 1758
F I H+A KV Y FL+KN D V ++ +++ S+ +VA LF GK
Sbjct: 548 FIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATTPGKG 607
Query: 1759 SS-------------VTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPG 1805
SS V+ TV +F+ SL L+E + P ++RC+KPN +K P
Sbjct: 608 SSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPF 667
Query: 1806 LFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGD---MC 1862
F+P + QLR GVLET+RI G+P R + F +RY LV K +L AN D +C
Sbjct: 668 HFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVK-KREL-ANTDKKAIC 725
Query: 1863 VSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRF 1922
SVL L K P+ ++ G +K+F + LE +R A + +Q+ +RG+ K ++
Sbjct: 726 RSVLENLIK-DPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKY 784
Query: 1923 RSLRHKIILLQSRARGYL-------------------------ARQRYQQMRRSLVKFRS 1957
L+ + LQ RG+L ARQ YQ++RR+ V ++
Sbjct: 785 HRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQA 844
Query: 1958 LVHAYVSRRRYLKLRAE 1974
A RR Y ++ E
Sbjct: 845 FTRAMFVRRTYRQVLME 861
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 511 bits (1316), Expect = e-144
Identities = 310/774 (40%), Positives = 436/774 (56%), Gaps = 27/774 (3%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRF-ERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281
G D+T L L E VL NL++RF + LIYTY G +LV++NPY+ IYG + + Y+G
Sbjct: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129
Query: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMN-QKRE 1340
+ +G+ PH+FAVA A+ +M ++NQ II+SGESG+GKT + K +RY A ++ E
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189
Query: 1341 VMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399
+ K+L + P++ES GNAKT RNDNSSRFGK++EI F + I GA YLLEKSR+
Sbjct: 190 ANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRV 249
Query: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459
VFQA+ ERNYHIFY+L A + L A+ + Y QGG+ I G DA +
Sbjct: 250 VFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTR 309
Query: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQIS 1519
A +LG S Q IFRILA ILHLGNV F + D+ + + +L+ +
Sbjct: 310 QACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPP--KHEPLCIFCDLMGVD 367
Query: 1520 PEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVN-ALVSPR 1578
E + + + T E P++ A +ARDA+AK +YA LF+W++ VN AL S
Sbjct: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAV 427
Query: 1579 QDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQEI 1638
+ I +LDIYGFE NSFEQ CINYANE LQ FN VF+ EQEEY++EQI W I
Sbjct: 428 KQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLI 487
Query: 1639 TFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHH-GANPLYSKPKMPLP 1697
F DNQPCINLI K GIL +LD++C P+ TD T+ QK + H L+ KP++
Sbjct: 488 DFYDNQPCINLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNK 546
Query: 1698 EFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQRLGK 1757
F I+H+A KV YQ FL+KN D V ++ + + S+ +++ LF +P
Sbjct: 547 AFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATS 606
Query: 1758 S--SSVTR------------LYKAH--TVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHK 1801
S + +TR + K H TV +F+ SL L+E + P ++RC+KPN
Sbjct: 607 SGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDF 666
Query: 1802 KEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDM 1861
K P F+ + QLR GVLET+RI GFP R +Q F RY L+ K L
Sbjct: 667 KFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQT 726
Query: 1862 CVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRR 1921
C +VL +L + + Y+ G +K+F + LE +R L A + +Q+ +RG+ ++++
Sbjct: 727 CKNVLEKLI-LDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKK 785
Query: 1922 FRSLRHKIILLQSRARGYLARQRYQQMRRSLVK--FRSLVHAYVSRRRYLKLRA 1973
+ +R I +Q RGY AR + +RR+ + YV RRRY RA
Sbjct: 786 YLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRA 839
Score = 51.6 bits (122), Expect = 1e-05
Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 2/81 (2%)
Query: 1898 REHVLNLAALTLQRCLRGFFIKRRFRSL--RHKIILLQSRARGYLARQRYQQMRRSLVKF 1955
R + A + LQ LRGF + R+R + HK +++Q R RG+LAR Y++ +++
Sbjct: 833 RYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYL 892
Query: 1956 RSLVHAYVSRRRYLKLRAEWR 1976
+ +++R KL+ E R
Sbjct: 893 QCCFRRMMAKRELKKLKIEAR 913
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 511 bits (1316), Expect = e-144
Identities = 310/774 (40%), Positives = 436/774 (56%), Gaps = 27/774 (3%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRF-ERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281
G D+T L L E VL NL++RF + LIYTY G +LV++NPY+ IYG + + Y+G
Sbjct: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129
Query: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMN-QKRE 1340
+ +G+ PH+FAVA A+ +M ++NQ II+SGESG+GKT + K +RY A ++ E
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189
Query: 1341 VMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399
+ K+L + P++ES GNAKT RNDNSSRFGK++EI F + I GA YLLEKSR+
Sbjct: 190 ANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRV 249
Query: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459
VFQA+ ERNYHIFY+L A + L A+ + Y QGG+ I G DA +
Sbjct: 250 VFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTR 309
Query: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQIS 1519
A +LG S Q IFRILA ILHLGNV F + D+ + + +L+ +
Sbjct: 310 QACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPP--KHEPLCIFCDLMGVD 367
Query: 1520 PEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVN-ALVSPR 1578
E + + + T E P++ A +ARDA+AK +YA LF+W++ VN AL S
Sbjct: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAV 427
Query: 1579 QDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQEI 1638
+ I +LDIYGFE NSFEQ CINYANE LQ FN VF+ EQEEY++EQI W I
Sbjct: 428 KQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLI 487
Query: 1639 TFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHH-GANPLYSKPKMPLP 1697
F DNQPCINLI K GIL +LD++C P+ TD T+ QK + H L+ KP++
Sbjct: 488 DFYDNQPCINLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNK 546
Query: 1698 EFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQRLGK 1757
F I+H+A KV YQ FL+KN D V ++ + + S+ +++ LF +P
Sbjct: 547 AFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATS 606
Query: 1758 S--SSVTR------------LYKAH--TVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHK 1801
S + +TR + K H TV +F+ SL L+E + P ++RC+KPN
Sbjct: 607 SGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDF 666
Query: 1802 KEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDM 1861
K P F+ + QLR GVLET+RI GFP R +Q F RY L+ K L
Sbjct: 667 KFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQT 726
Query: 1862 CVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRR 1921
C +VL +L + + Y+ G +K+F + LE +R L A + +Q+ +RG+ ++++
Sbjct: 727 CKNVLEKLI-LDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKK 785
Query: 1922 FRSLRHKIILLQSRARGYLARQRYQQMRRSLVK--FRSLVHAYVSRRRYLKLRA 1973
+ +R I +Q RGY AR + +RR+ + YV RRRY RA
Sbjct: 786 YLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRA 839
Score = 51.6 bits (122), Expect = 1e-05
Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 2/81 (2%)
Query: 1898 REHVLNLAALTLQRCLRGFFIKRRFRSL--RHKIILLQSRARGYLARQRYQQMRRSLVKF 1955
R + A + LQ LRGF + R+R + HK +++Q R RG+LAR Y++ +++
Sbjct: 833 RYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYL 892
Query: 1956 RSLVHAYVSRRRYLKLRAEWR 1976
+ +++R KL+ E R
Sbjct: 893 QCCFRRMMAKRELKKLKIEAR 913
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 502 bits (1292), Expect = e-141
Identities = 290/778 (37%), Positives = 454/778 (58%), Gaps = 35/778 (4%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
GV DM LE L E T ++NLK RF+ + IYTYIGS+++SVNPY+ IY PE+V++Y R
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
E PH+FA+++ A+ + D ++QCI+I+GESG+GKTEA+KL++ Y+AA+ K +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 1343 QQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399
Q+K +L++ P+LE+FGNAKTVRNDNSSRFGK+++I F G G + S YLLEKSR+
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459
V Q + ERN+H+FY+LL+G +L L+ + Y + ++ G DA +FR +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVR 255
Query: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFE-KYETDAQEVASVVSAREIQAVAELLQI 1518
AM+++GF + +S+ ++A++L LGN+ F+ + + + + + E++ + EL I
Sbjct: 256 NAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGI 315
Query: 1519 SPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVSPR 1578
L++A +F+ E +EK+ T L V A ARDA+AK LY+ LFSWL+ R+N + +
Sbjct: 316 DQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQ 375
Query: 1579 QDTLS--IAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQ 1636
+ +LDIYGFE NSFEQ INY NE LQ +F ++ +EEQEEYIRE I+W
Sbjct: 376 TKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWT 435
Query: 1637 EITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQK----CHYHHGANPLYSK 1691
I + +N +LI GIL +LD++C P TD TFL+K C H SK
Sbjct: 436 HIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSK 495
Query: 1692 -------PKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFS 1744
+P F I+HYAGKV YQV F+DKN+D + +D+ ++ ++ LF
Sbjct: 496 CSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLF- 554
Query: 1745 SHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEP 1804
P+ P ++ L + T ++F+ S+ L++ ++ NP ++RC+KPN KK
Sbjct: 555 ---PEGNPAKI-------NLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAA 604
Query: 1805 GLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRY--CCLVALKH-DLPANGDM 1861
+F +V Q+RY G+LE VR+R+ G+ R ++ ++RY C H PA
Sbjct: 605 HIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSG- 663
Query: 1862 CVSVLSRLCKVMPNMYRVGVSKLFLKE-HLYQLLESMREHVLNLAALTLQRCLRGFFIKR 1920
V VL ++ Y G SK+F++ LE +R+ L A +Q+ RG+ +
Sbjct: 664 -VEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722
Query: 1921 RFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQ 1978
F ++ I++ + R Y ++RYQQ + S + +S + + +R+ +L+ + RC+
Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCK 780
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 502 bits (1292), Expect = e-141
Identities = 290/778 (37%), Positives = 454/778 (58%), Gaps = 35/778 (4%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
GV DM LE L E T ++NLK RF+ + IYTYIGS+++SVNPY+ IY PE+V++Y R
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
E PH+FA+++ A+ + D ++QCI+I+GESG+GKTEA+KL++ Y+AA+ K +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 1343 QQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399
Q+K +L++ P+LE+FGNAKTVRNDNSSRFGK+++I F G G + S YLLEKSR+
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459
V Q + ERN+H+FY+LL+G +L L+ + Y + ++ G DA +FR +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVR 255
Query: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFE-KYETDAQEVASVVSAREIQAVAELLQI 1518
AM+++GF + +S+ ++A++L LGN+ F+ + + + + + E++ + EL I
Sbjct: 256 NAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGI 315
Query: 1519 SPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVSPR 1578
L++A +F+ E +EK+ T L V A ARDA+AK LY+ LFSWL+ R+N + +
Sbjct: 316 DQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQ 375
Query: 1579 QDTLS--IAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQ 1636
+ +LDIYGFE NSFEQ INY NE LQ +F ++ +EEQEEYIRE I+W
Sbjct: 376 TKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWT 435
Query: 1637 EITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQK----CHYHHGANPLYSK 1691
I + +N +LI GIL +LD++C P TD TFL+K C H SK
Sbjct: 436 HIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSK 495
Query: 1692 -------PKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFS 1744
+P F I+HYAGKV YQV F+DKN+D + +D+ ++ ++ LF
Sbjct: 496 CSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLF- 554
Query: 1745 SHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEP 1804
P+ P ++ L + T ++F+ S+ L++ ++ NP ++RC+KPN KK
Sbjct: 555 ---PEGNPAKI-------NLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAA 604
Query: 1805 GLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRY--CCLVALKH-DLPANGDM 1861
+F +V Q+RY G+LE VR+R+ G+ R ++ ++RY C H PA
Sbjct: 605 HIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSG- 663
Query: 1862 CVSVLSRLCKVMPNMYRVGVSKLFLKE-HLYQLLESMREHVLNLAALTLQRCLRGFFIKR 1920
V VL ++ Y G SK+F++ LE +R+ L A +Q+ RG+ +
Sbjct: 664 -VEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722
Query: 1921 RFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQ 1978
F ++ I++ + R Y ++RYQQ + S + +S + + +R+ +L+ + RC+
Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCK 780
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 502 bits (1292), Expect = e-141
Identities = 290/778 (37%), Positives = 454/778 (58%), Gaps = 35/778 (4%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
GV DM LE L E T ++NLK RF+ + IYTYIGS+++SVNPY+ IY PE+V++Y R
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
E PH+FA+++ A+ + D ++QCI+I+GESG+GKTEA+KL++ Y+AA+ K +
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 1343 QQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399
Q+K +L++ P+LE+FGNAKTVRNDNSSRFGK+++I F G G + S YLLEKSR+
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459
V Q + ERN+H+FY+LL+G +L L+ + Y + ++ G DA +FR +
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAANFRTVR 255
Query: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFE-KYETDAQEVASVVSAREIQAVAELLQI 1518
AM+++GF + +S+ ++A++L LGN+ F+ + + + + + E++ + EL I
Sbjct: 256 NAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTGI 315
Query: 1519 SPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVSPR 1578
L++A +F+ E +EK+ T L V A ARDA+AK LY+ LFSWL+ R+N + +
Sbjct: 316 DQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQ 375
Query: 1579 QDTLS--IAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQ 1636
+ +LDIYGFE NSFEQ INY NE LQ +F ++ +EEQEEYIRE I+W
Sbjct: 376 TKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDIEWT 435
Query: 1637 EITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQK----CHYHHGANPLYSK 1691
I + +N +LI GIL +LD++C P TD TFL+K C H SK
Sbjct: 436 HIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESRMSK 495
Query: 1692 -------PKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFS 1744
+P F I+HYAGKV YQV F+DKN+D + +D+ ++ ++ LF
Sbjct: 496 CSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKSLF- 554
Query: 1745 SHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEP 1804
P+ P ++ L + T ++F+ S+ L++ ++ NP ++RC+KPN KK
Sbjct: 555 ---PEGNPAKI-------NLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAA 604
Query: 1805 GLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRY--CCLVALKH-DLPANGDM 1861
+F +V Q+RY G+LE VR+R+ G+ R ++ ++RY C H PA
Sbjct: 605 HIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSG- 663
Query: 1862 CVSVLSRLCKVMPNMYRVGVSKLFLKE-HLYQLLESMREHVLNLAALTLQRCLRGFFIKR 1920
V VL ++ Y G SK+F++ LE +R+ L A +Q+ RG+ +
Sbjct: 664 -VEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRT 722
Query: 1921 RFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQ 1978
F ++ I++ + R Y ++RYQQ + S + +S + + +R+ +L+ + RC+
Sbjct: 723 HFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCK 780
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 500 bits (1288), Expect = e-141
Identities = 306/800 (38%), Positives = 448/800 (56%), Gaps = 49/800 (6%)
Query: 1223 GVEDMTQLEDLQETTVLSNLKIRF-ERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281
G D+T L L E VL NL+IRF E LIYTY G ILV++NPY+ IYG + Y+G
Sbjct: 68 GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127
Query: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQK-RE 1340
+ +G+ PH+FAVA A+ +M +NQ II+SGESG+GKT + + +RY A +++
Sbjct: 128 QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187
Query: 1341 VMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399
+ K+L + P+ E+ GNAKT RNDNSSRFGK+ EI F E I GA S YLLEKSR+
Sbjct: 188 AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRV 247
Query: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459
VFQ++NERNYHIFY+L A + L AE + Y GGN I G +D +
Sbjct: 248 VFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQ 307
Query: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQIS 1519
+LGF + Q +F+ILA+ILHLGNV + V+ S ++ ELL +
Sbjct: 308 KTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDS--HLKVFCELLGLE 365
Query: 1520 PEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV--SP 1577
+ + + + T E + P+T AV+ARDA+AK +YA LF +++ R+N + S
Sbjct: 366 SGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQFSG 425
Query: 1578 RQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQE 1637
+Q T I +LDIYGFE NSFEQ CINYANE LQ FN VF+ EQEEY++E I W
Sbjct: 426 KQHTF-IGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPWTL 484
Query: 1638 ITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHH-GANPLYSKPKMPL 1696
I F DNQP I+LI K GIL +LD++C P TD +LQK + + NPL+ KP+M
Sbjct: 485 IDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSN 543
Query: 1697 PEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSH----APQAAP 1752
F I+H+A KV Y+ FL+KN D V ++++ S+ + A+ F + +P +
Sbjct: 544 TSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPFGSM 603
Query: 1753 QRLGKSSSVTRLYKAH---TVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEP 1809
+ + V + H TV +KF+ SL L+E + P ++RC+KPN +K P F+
Sbjct: 604 ITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDS 663
Query: 1810 DVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANG--DMCVSVLS 1867
++ QLR GVLET+RI + +P R + F RY L+ K +L + ++C VL
Sbjct: 664 KRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMT-KQELSFSDKKEVCKVVLH 722
Query: 1868 RLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRF----- 1922
RL + N Y+ G +K+F + LE +R L + + +Q+ +RG+ +++F
Sbjct: 723 RLIQ-DSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERR 781
Query: 1923 ------------RSLRHKI-----------ILLQSRARGYLARQRYQQMRRSLVKFRSLV 1959
+++R I I++Q RGYL R YQ +R + + ++
Sbjct: 782 AALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYS 841
Query: 1960 HAYVSRRRYLKLRAEWRCQV 1979
+++RRRY K+ E + +
Sbjct: 842 RGFLARRRYRKMLEEHKAVI 861
Score = 51.2 bits (121), Expect = 2e-05
Identities = 27/74 (36%), Positives = 44/74 (59%), Gaps = 10/74 (13%)
Query: 1885 FLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSL--RHKIILLQSRARGYLAR 1942
+L LYQL+ +A +T+Q RGF +RR+R + HK ++LQ AR +LAR
Sbjct: 821 YLVRSLYQLIR--------MATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLAR 872
Query: 1943 QRYQQMRRSLVKFR 1956
+R+Q +RR ++ +
Sbjct: 873 RRFQSIRRFVLNIQ 886
>gi|4885503 myosin IA [Homo sapiens]
Length = 1043
Score = 489 bits (1260), Expect = e-137
Identities = 292/775 (37%), Positives = 453/775 (58%), Gaps = 39/775 (5%)
Query: 1220 GEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQY 1279
G GVED+ LE L E ++L NL++R+E IYTYIG++++SVNPYQ IYGPE + +Y
Sbjct: 6 GSVGVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKY 65
Query: 1280 NGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKR 1339
E PH++A+AN+A+ + D ++QCI+I+GESGSGKTEA+KL++ Y+AA+ K
Sbjct: 66 QDYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKG 125
Query: 1340 EVMQQIK--ILEATPLLESFGNAKTVRNDNSSRFGKF--VEIFLEGGVISGAITSQYLLE 1395
E + +K +L++ P+LE+FGNAKT+RN+NSSRFGK+ +E +G + G IT+ YLLE
Sbjct: 126 EQVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITN-YLLE 184
Query: 1396 KSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAET-YYYLNQGGNCEIAGKSDADD 1454
KSR+V Q K ERN+HIFY+LLAG QL +A L+ T Y YLN + + G DA
Sbjct: 185 KSRLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVS-RVDGMDDASS 243
Query: 1455 FRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYF-EKYETDAQEVASVVSAREIQAVA 1513
FR + +AM V+GFS E+ + + + +L LGNV ++++ + + R ++ +
Sbjct: 244 FRAVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIG 303
Query: 1514 ELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVN- 1572
E++ ++ E +++A+ + ET +EK+ T L V A ARDA+AK +Y+ LF W++ R+N
Sbjct: 304 EMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363
Query: 1573 -ALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIRE 1631
V + + +LDIYGFE L NSFEQ INY NE LQ +F ++ +EEQEEY RE
Sbjct: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
Query: 1632 QIDWQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQKC------HYHHG 1684
I W ++ + DN LI GIL +LD++C P +D TFL K H H+
Sbjct: 424 GIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYE 483
Query: 1685 ANPLYSKPK-----MPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVV 1739
+ + + M L F I HYAGKVTY V F+DKN+D + +D+L +++ ++
Sbjct: 484 SKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLL 543
Query: 1740 AHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPN 1799
LF P+ A L + T A+F+ S+ L++ + +P ++RC+KPN
Sbjct: 544 RSLFPEGNPKQA-----------SLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPN 592
Query: 1800 HKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANG 1859
++ G F D+V Q RY G+LE VR+R+ G+ R + F++RY L G
Sbjct: 593 EHQQRGQFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGG 652
Query: 1860 DM--CVSVLSRLCKVMPNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCLRG 1915
D VL L + G +K+F++ + L+ L E R + LA L +Q+ RG
Sbjct: 653 DREGVEKVLGEL-SMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATL-IQKIYRG 710
Query: 1916 FFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLK 1970
+ + ++ +R IL+ S RG + ++ Y +++ S++ ++ V + +R+ Y K
Sbjct: 711 WRCRTHYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRK 765
>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
Length = 1341
Score = 482 bits (1240), Expect = e-135
Identities = 299/793 (37%), Positives = 451/793 (56%), Gaps = 74/793 (9%)
Query: 1216 REQHGEDGV-----EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGI 1270
R H ED +D+ LE L E T++ L+ R+ LIYTY+G IL+++NP+Q I
Sbjct: 332 RPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSI 391
Query: 1271 YGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILR 1330
Y P+ + Y+G NPPH+FA A+ A+ M+ ++QCI+ISGESGSGKTE+ LI++
Sbjct: 392 YSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQ 451
Query: 1331 YLAAMNQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVE-IFLEGGVISGAIT 1389
+L + + + KIL+ L+E+FGN+ T NDNSSRFGK++E +F GV+ GA
Sbjct: 452 HLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARI 511
Query: 1390 SQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQA-FSLQEAETYYYLNQGGNCEIAG 1448
S+YLLEKSR++ QA E+N+HIFY + AGL Q + + F L E + Y+ +
Sbjct: 512 SEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHD 571
Query: 1449 KSDADDFRRLLAAME----VLGFSSEDQDSIFRILASILHLGNVYF----EKYETDAQEV 1500
+ + +RR A++ ++GF+ ++ S++RILA IL++GN+ F +++TD EV
Sbjct: 572 ITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEV 631
Query: 1501 ASVVSAREIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLY 1560
+A +Q A +L ISPE LQ+A+T T E I TV+ A D RDA++K LY
Sbjct: 632 P---NAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALY 688
Query: 1561 ALLFSWLITRVNALVSPRQDT------LSIAILDIYGFEDLSFNSFEQLCINYANENLQY 1614
LFSW++ R+N L+ P ++ +++ ILDI+GFE+ NSFEQLCIN ANE +QY
Sbjct: 689 GRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQY 748
Query: 1615 LFNKIVFQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHT 1674
FN+ VF EQ EY E ID + + DN+P +++ KP G+L +LD++ FPQATD T
Sbjct: 749 YFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQT 808
Query: 1675 FLQK------CHYHHGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVL 1728
+ K C Y + +PK F I+HYAGKV Y L+KN D + DV+
Sbjct: 809 LVDKFEDNLRCKY-------FWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVV 861
Query: 1729 DLFVRSRTRVVAHLFS------SHAPQAAPQRLGKSSSV--------------------- 1761
+ S ++ LFS + Q + SSS+
Sbjct: 862 VVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPE 921
Query: 1762 -TRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSG 1820
T K TVA+ F+ SL+DL+ KM P F+RC+KPN +E F + V+AQLR +G
Sbjct: 922 ETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTG 981
Query: 1821 VLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLP-ANGDMCVSVLSRLCKVMPNMYRV 1879
+LETV IR++G+ R+ F+ F+ RY L H P A+ + CV++L K + + +
Sbjct: 982 ILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILE---KSRLDHWVL 1038
Query: 1880 GVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHK----IILLQSR 1935
G +K+FLK + + L + V+ + LQ +G+ RR++ +R K I +QS
Sbjct: 1039 GKTKVFLKYYHVEQLNLLLREVIG-RVVVLQAYTKGWLGARRYKKVREKREKGAIAIQSA 1097
Query: 1936 ARGYLARQRYQQM 1948
RGY AR++++++
Sbjct: 1098 WRGYDARRKFKKI 1110
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 479 bits (1233), Expect = e-134
Identities = 289/752 (38%), Positives = 424/752 (56%), Gaps = 31/752 (4%)
Query: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRA 1283
VEDM +L L E +VL NLK R+ LIYTY G V +NPY+ IY E V+ Y G+
Sbjct: 83 VEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK 142
Query: 1284 LGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAM-----NQK 1338
E PPH++A+ + A+ M+ +++Q I+ +GESG+GKTE TK +++YLA + ++K
Sbjct: 143 RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKK 202
Query: 1339 REVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKS 1397
+ + ++L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA YLLEKS
Sbjct: 203 DQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKS 262
Query: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRR 1457
R + QAK ER +HIFY LL+G L+ L+ Y +L+ G+ I G+ D D F+
Sbjct: 263 RAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLS-NGHVTIPGQQDKDMFQE 321
Query: 1458 LLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQ 1517
+ AM ++G E+Q + R+++ +L LGN+ F+K Q AS+ Q V+ LL
Sbjct: 322 TMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQ--ASMPDNTAAQKVSHLLG 379
Query: 1518 ISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV-- 1575
I+ + I + R+ + T E A A +A+AK Y +F WL+ R+N +
Sbjct: 380 INVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDK 439
Query: 1576 SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDW 1635
+ RQ I ILDI GFE NSFEQLCINY NE LQ LFN +F EQEEY RE I+W
Sbjct: 440 TKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 499
Query: 1636 QEITFA-DNQPCINLIS--LKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKP 1692
I F D QPCI+LI P GIL +LD++C FP+ATD +F++K G +P + KP
Sbjct: 500 NFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKP 559
Query: 1693 KM--PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSS-HAPQ 1749
K +F I HYAGKV Y+ ++L KN D + ++ L +S + V+ L+
Sbjct: 560 KQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRII 619
Query: 1750 AAPQRLGKSSSV------TRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKE 1803
Q G S + TR TV +++ L L+ + NP F+RC+ PNH+K+
Sbjct: 620 GLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKK 679
Query: 1804 PGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLP---ANGD 1860
G +P +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L + +P +G
Sbjct: 680 AGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILT--PNSIPKGFMDGK 737
Query: 1861 MCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKR 1920
++ + ++ N+YR+G SK+F + + LE R+ + + Q C RG+ ++
Sbjct: 738 QACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARK 797
Query: 1921 RFRSLRHKII---LLQSRARGYLARQRYQQMR 1949
F + ++ +LQ YL + +Q R
Sbjct: 798 AFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWR 829
>gi|145275208 myosin IIIA [Homo sapiens]
Length = 1616
Score = 476 bits (1225), Expect = e-133
Identities = 287/774 (37%), Positives = 435/774 (56%), Gaps = 57/774 (7%)
Query: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRA 1283
V+D+ LE L E TV L+ + R+ IY Y+G IL+++NP+Q G+Y + + Y G
Sbjct: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
Query: 1284 LGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ 1343
+PPH+FA+A+L + M+ +QCI+ISGESG+GKTE L+++ L + +
Sbjct: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTL 459
Query: 1344 QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVFQ 1402
Q KIL+ L+E+FGNA T+ NDNSSRFGK++E+ F G + GA S+YLLEKSR++ Q
Sbjct: 460 QEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQ 519
Query: 1403 AKNERNYHIFYELLAGLPAQLRQA-FSLQEAETYYYLNQGGNCEIAGKSD-------ADD 1454
A E+N+HIFY + AGL + + A + L E + YL N + D
Sbjct: 520 AIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQ---NDHLRTVQDIMNNSFYKSQ 576
Query: 1455 FRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQ-EVASVVSAREIQAVA 1513
+ + +V+GF+ E SI+ ILA+IL++GN+ F T+ Q + + + + ++ A
Sbjct: 577 YELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENCA 636
Query: 1514 ELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNA 1573
LL I + LQ+A+T T E I P TVE A D RDA+AK LY LFSW++ +N+
Sbjct: 637 SLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINS 696
Query: 1574 LV------SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEE 1627
L+ S D LSI ILDI+GFE+ NSFEQLCIN ANE +QY +N+ VF EQ E
Sbjct: 697 LLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNE 756
Query: 1628 YIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANP 1687
Y+ E +D + I + DN P +++ KP G+L +LD++ FP+ATD T ++K + +
Sbjct: 757 YLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQY 816
Query: 1688 LYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHA 1747
+ +M L F I HYAGKV Y FL KN D + D++ L S V+ L +
Sbjct: 817 FWRPKRMEL-SFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPL 875
Query: 1748 PQAAPQRLGKSSSV----------------------------TRLYKAHTVAAKFQQSLL 1779
+ K+ +V T K TVA+ F+ SL+
Sbjct: 876 TKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFRYSLM 935
Query: 1780 DLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQ 1839
DL+ KM P F+RC+KPN +++ ++ + V+ QLRY+G+LET RIR+ GF R+ F
Sbjct: 936 DLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHRILFA 995
Query: 1840 GFIDRYCCLVALKHDLP-ANGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMR 1898
FI RY L + P + D C ++L K + + +G +K+FLK + + L MR
Sbjct: 996 NFIKRYYLLCYKSSEEPRMSPDTCATILE---KAGLDNWALGKTKVFLKYYHVEQLNLMR 1052
Query: 1899 EHVLNLAALTLQRCLRGFFIKRRFRSLRHK----IILLQSRARGYLARQRYQQM 1948
+ ++ L +Q C+R F RR++ ++ K I++QS ARG+L R++ +++
Sbjct: 1053 KEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKEI 1105
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 474 bits (1221), Expect = e-133
Identities = 309/819 (37%), Positives = 448/819 (54%), Gaps = 36/819 (4%)
Query: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRA 1283
VEDM +L L E +VL NLK R+ LIYTY G V +NPY+ IY ++ Y G+
Sbjct: 87 VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146
Query: 1284 LGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLA--AMNQKREV 1341
E PPH++A++ A+ ML +++Q I+ +GESG+GKTE TK +++YLA A + K
Sbjct: 147 RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206
Query: 1342 MQQI------KILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLL 1394
I ++L+A P+LESFGNAKTV+NDNSSRFGKF+ I F G I GA YLL
Sbjct: 207 DHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
Query: 1395 EKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADD 1454
EKSR V QAK+ER +HIFY+LL+G L+ L+ Y +L+ G I G+ D D+
Sbjct: 267 EKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLS-NGYIPIPGQQDKDN 325
Query: 1455 FRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAE 1514
F+ + AM ++GFS E+ S+ ++++S+L GN+ F+K Q AS+ Q +
Sbjct: 326 FQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQ--ASMPENTVAQKLCH 383
Query: 1515 LLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNAL 1574
LL ++ +AI + R+ + T E A A +A+AK Y LF WL+ R+N
Sbjct: 384 LLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKA 443
Query: 1575 V--SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQ 1632
+ + RQ I ILDI GFE NSFEQLCINY NE LQ LFN +F EQEEY RE
Sbjct: 444 LDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 503
Query: 1633 IDWQEITFA-DNQPCINLIS--LKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLY 1689
I+W I F D QPCI+LI P G+L +LD++C FP+ATD TF++K G++ +
Sbjct: 504 IEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKF 563
Query: 1690 SKPKM--PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSS-- 1745
KP+ +F I HYAGKV Y+ ++L KN D + +V L +S R VA L+
Sbjct: 564 QKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVD 623
Query: 1746 -----HAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNH 1800
+ S+ T+ TV +++SL L+ + NP F+RC+ PNH
Sbjct: 624 RIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNH 683
Query: 1801 KKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLP---A 1857
+K G +P +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L + +P
Sbjct: 684 EKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILT--PNAIPKGFM 741
Query: 1858 NGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFF 1917
+G + R ++ PN+YR+G SK+F + + LE R+ + + Q RG+
Sbjct: 742 DGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYL 801
Query: 1918 IKRRFRSLRHKII---LLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAE 1974
++ F + ++ +LQ YL + R+ Q R K + L+ + L+ + E
Sbjct: 802 ARKAFAKKQQQLSALKVLQRNCAAYL-KLRHWQWWRVFTKVKPLLQV-TRQEEELQAKDE 859
Query: 1975 WRCQVEGALLWEQEELSKREVVAVGHLEVPAELAGLLQA 2013
+V+ + EL + E LE LA LQA
Sbjct: 860 ELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA 898
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 474 bits (1219), Expect = e-133
Identities = 289/755 (38%), Positives = 422/755 (55%), Gaps = 34/755 (4%)
Query: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRA 1283
VEDM +L L E +VL NL+ R+ LIYTY G V VNPY+ IY + V Y G+
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 1284 LGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ 1343
E PPH++A+A+ A+ ML +++Q I+ +GESG+GKTE TK +++YLA + + +
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 1344 QIKI--------LEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLL 1394
I L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA YLL
Sbjct: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
Query: 1395 EKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADD 1454
EKSR + QA++ER +HIFY ++AG ++R L+ Y +L+ G I D +
Sbjct: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEM 325
Query: 1455 FRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAE 1514
F+ + AM ++GFS E+Q SI ++++S+L LGN+ F+K Q AS+ Q V
Sbjct: 326 FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQ--ASMPDNTAAQKVCH 383
Query: 1515 LLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNAL 1574
L+ I+ ++I + R+ + T E A A +A+AK Y LF W++TRVN
Sbjct: 384 LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 443
Query: 1575 V--SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQ 1632
+ + RQ + ILDI GFE NSFEQLCINY NE LQ LFN +F EQEEY RE
Sbjct: 444 LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 503
Query: 1633 IDWQEITFA-DNQPCINLISL--KPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLY 1689
I+W I F D QPCI LI P G+L +LD++C FP+ATD +F++K G++P +
Sbjct: 504 IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKF 563
Query: 1690 SKPKM--PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHA 1747
KPK EF+I HYAGKV Y +L KN D + +V L S + VA L+
Sbjct: 564 QKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
Query: 1748 PQAAPQRLGK-------SSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNH 1800
++ K S+S T+ TV +++ L L+ + P F+RC+ PNH
Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 1801 KKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLP---A 1857
+K G + +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L A + +P
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAA--NAIPKGFM 741
Query: 1858 NGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFF 1917
+G ++ + ++ PN+YR+G SK+F + + LE R+ + + Q RG+
Sbjct: 742 DGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL 801
Query: 1918 IKRRFRSLRHKII---LLQSRARGYLARQRYQQMR 1949
++ F + ++ ++Q YL + +Q R
Sbjct: 802 ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWR 836
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 474 bits (1219), Expect = e-133
Identities = 289/755 (38%), Positives = 422/755 (55%), Gaps = 34/755 (4%)
Query: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRA 1283
VEDM +L L E +VL NL+ R+ LIYTY G V VNPY+ IY + V Y G+
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 1284 LGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ 1343
E PPH++A+A+ A+ ML +++Q I+ +GESG+GKTE TK +++YLA + + +
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 1344 QIKI--------LEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLL 1394
I L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA YLL
Sbjct: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
Query: 1395 EKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADD 1454
EKSR + QA++ER +HIFY ++AG ++R L+ Y +L+ G I D +
Sbjct: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEM 325
Query: 1455 FRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAE 1514
F+ + AM ++GFS E+Q SI ++++S+L LGN+ F+K Q AS+ Q V
Sbjct: 326 FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQ--ASMPDNTAAQKVCH 383
Query: 1515 LLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNAL 1574
L+ I+ ++I + R+ + T E A A +A+AK Y LF W++TRVN
Sbjct: 384 LMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKA 443
Query: 1575 V--SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQ 1632
+ + RQ + ILDI GFE NSFEQLCINY NE LQ LFN +F EQEEY RE
Sbjct: 444 LDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREG 503
Query: 1633 IDWQEITFA-DNQPCINLISL--KPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLY 1689
I+W I F D QPCI LI P G+L +LD++C FP+ATD +F++K G++P +
Sbjct: 504 IEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKF 563
Query: 1690 SKPKM--PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHA 1747
KPK EF+I HYAGKV Y +L KN D + +V L S + VA L+
Sbjct: 564 QKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
Query: 1748 PQAAPQRLGK-------SSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNH 1800
++ K S+S T+ TV +++ L L+ + P F+RC+ PNH
Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 1801 KKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLP---A 1857
+K G + +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L A + +P
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAA--NAIPKGFM 741
Query: 1858 NGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFF 1917
+G ++ + ++ PN+YR+G SK+F + + LE R+ + + Q RG+
Sbjct: 742 DGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL 801
Query: 1918 IKRRFRSLRHKII---LLQSRARGYLARQRYQQMR 1949
++ F + ++ ++Q YL + +Q R
Sbjct: 802 ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWR 836
>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
Length = 1314
Score = 472 bits (1215), Expect = e-132
Identities = 295/784 (37%), Positives = 442/784 (56%), Gaps = 76/784 (9%)
Query: 1216 REQHGEDGV-----EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGI 1270
R H ED +D+ LE L E T++ L+ R+ LIYTY+G IL+++NP+Q I
Sbjct: 332 RPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSI 391
Query: 1271 YGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILR 1330
Y P+ + Y+G NPPH+FA A+ A+ M+ ++QCI+ISGESGSGKTE+ LI++
Sbjct: 392 YSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQ 451
Query: 1331 YLAAMNQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVE-IFLEGGVISGAIT 1389
+L + + + KIL+ L+E+FGN+ T NDNSSRFGK++E +F GV+ GA
Sbjct: 452 HLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARI 511
Query: 1390 SQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQA-FSLQEAETYYYLNQGGNCEIAG 1448
S+YLLEKSR++ QA E+N+HIFY + AGL Q + + F L E + Y+ +
Sbjct: 512 SEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHD 571
Query: 1449 KSDADDFRRLLAAME----VLGFSSEDQDSIFRILASILHLGNVYF----EKYETDAQEV 1500
+ + +RR A++ ++GF+ ++ S++RILA IL++GN+ F +++TD EV
Sbjct: 572 ITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEV 631
Query: 1501 ASVVSAREIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLY 1560
+A +Q A +L ISPE LQ+A+T T E I TV+ A D RDA++K LY
Sbjct: 632 P---NAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALY 688
Query: 1561 ALLFSWLITRVNALVSPRQDT------LSIAILDIYGFEDLSFNSFEQLCINYANENLQY 1614
LFSW++ R+N L+ P ++ +++ ILDI+GFE+ NSFEQLCIN ANE +QY
Sbjct: 689 GRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQY 748
Query: 1615 LFNKIVFQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHT 1674
FN+ VF EQ EY E ID + + DN+P +++ KP G+L +LD++ FPQATD T
Sbjct: 749 YFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQT 808
Query: 1675 FLQK------CHYHHGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVL 1728
+ K C Y + +PK F I+HYAGKV Y L+KN D + DV+
Sbjct: 809 LVDKFEDNLRCKY-------FWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVV 861
Query: 1729 DLFVRSRTRVVAHLFS------SHAPQAAPQRLGKSSSV--------------------- 1761
+ S ++ LFS + Q + SSS+
Sbjct: 862 VVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEVIRHPE 921
Query: 1762 -TRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSG 1820
T K TVA+ F+ SL+DL+ KM P F+RC+KPN +E F + V+AQLR +G
Sbjct: 922 ETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTG 981
Query: 1821 VLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLP-ANGDMCVSVLSRLCKVMPNMYRV 1879
+LETV IR++G+ R+ F+ F+ RY L H P A+ + CV++L K + + +
Sbjct: 982 ILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILE---KSRLDHWVL 1038
Query: 1880 GVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHKIILLQSRARGY 1939
G +K+FLK + + L + V+ + LQ +G+ RR++ +R K R +G
Sbjct: 1039 GKTKVFLKYYHVEQLNLLLREVIG-RVVVLQAYTKGWLGARRYKKVREK------REKGA 1091
Query: 1940 LARQ 1943
+A Q
Sbjct: 1092 IAIQ 1095
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 471 bits (1212), Expect = e-132
Identities = 289/762 (37%), Positives = 422/762 (55%), Gaps = 41/762 (5%)
Query: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRA 1283
VEDM +L L E +VL NL+ R+ LIYTY G V VNPY+ IY + V Y G+
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 1284 LGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ 1343
E PPH++A+A+ A+ ML +++Q I+ +GESG+GKTE TK +++YLA + + +
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 1344 QIKI---------------LEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGA 1387
I L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA
Sbjct: 207 DTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 266
Query: 1388 ITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIA 1447
YLLEKSR + QA++ER +HIFY ++AG ++R L+ Y +L+ G I
Sbjct: 267 NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIP 325
Query: 1448 GKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAR 1507
D + F+ + AM ++GFS E+Q SI ++++S+L LGN+ F+K Q AS+
Sbjct: 326 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQ--ASMPDNT 383
Query: 1508 EIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWL 1567
Q V L+ I+ ++I + R+ + T E A A +A+AK Y LF W+
Sbjct: 384 AAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWI 443
Query: 1568 ITRVNALV--SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQ 1625
+TRVN + + RQ + ILDI GFE NSFEQLCINY NE LQ LFN +F EQ
Sbjct: 444 LTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQ 503
Query: 1626 EEYIREQIDWQEITFA-DNQPCINLISL--KPYGILRILDDQCCFPQATDHTFLQKCHYH 1682
EEY RE I+W I F D QPCI LI P G+L +LD++C FP+ATD +F++K
Sbjct: 504 EEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTE 563
Query: 1683 HGANPLYSKPKM--PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA 1740
G++P + KPK EF+I HYAGKV Y +L KN D + +V L S + VA
Sbjct: 564 QGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVA 623
Query: 1741 HLFSSHAPQAAPQRLGK-------SSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFM 1793
L+ ++ K S+S T+ TV +++ L L+ + P F+
Sbjct: 624 DLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFV 683
Query: 1794 RCLKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKH 1853
RC+ PNH+K G + +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L A +
Sbjct: 684 RCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAA--N 741
Query: 1854 DLP---ANGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQ 1910
+P +G ++ + ++ PN+YR+G SK+F + + LE R+ + + Q
Sbjct: 742 AIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQ 801
Query: 1911 RCLRGFFIKRRFRSLRHKII---LLQSRARGYLARQRYQQMR 1949
RG+ ++ F + ++ ++Q YL + +Q R
Sbjct: 802 AMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWR 843
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 471 bits (1212), Expect = e-132
Identities = 289/762 (37%), Positives = 422/762 (55%), Gaps = 41/762 (5%)
Query: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRA 1283
VEDM +L L E +VL NL+ R+ LIYTY G V VNPY+ IY + V Y G+
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 1284 LGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ 1343
E PPH++A+A+ A+ ML +++Q I+ +GESG+GKTE TK +++YLA + + +
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 1344 QIKI---------------LEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGA 1387
I L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA
Sbjct: 207 DTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 266
Query: 1388 ITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIA 1447
YLLEKSR + QA++ER +HIFY ++AG ++R L+ Y +L+ G I
Sbjct: 267 NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIP 325
Query: 1448 GKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAR 1507
D + F+ + AM ++GFS E+Q SI ++++S+L LGN+ F+K Q AS+
Sbjct: 326 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQ--ASMPDNT 383
Query: 1508 EIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWL 1567
Q V L+ I+ ++I + R+ + T E A A +A+AK Y LF W+
Sbjct: 384 AAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWI 443
Query: 1568 ITRVNALV--SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQ 1625
+TRVN + + RQ + ILDI GFE NSFEQLCINY NE LQ LFN +F EQ
Sbjct: 444 LTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQ 503
Query: 1626 EEYIREQIDWQEITFA-DNQPCINLISL--KPYGILRILDDQCCFPQATDHTFLQKCHYH 1682
EEY RE I+W I F D QPCI LI P G+L +LD++C FP+ATD +F++K
Sbjct: 504 EEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTE 563
Query: 1683 HGANPLYSKPKM--PLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA 1740
G++P + KPK EF+I HYAGKV Y +L KN D + +V L S + VA
Sbjct: 564 QGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVA 623
Query: 1741 HLFSSHAPQAAPQRLGK-------SSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFM 1793
L+ ++ K S+S T+ TV +++ L L+ + P F+
Sbjct: 624 DLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFV 683
Query: 1794 RCLKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKH 1853
RC+ PNH+K G + +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L A +
Sbjct: 684 RCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAA--N 741
Query: 1854 DLP---ANGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQ 1910
+P +G ++ + ++ PN+YR+G SK+F + + LE R+ + + Q
Sbjct: 742 AIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQ 801
Query: 1911 RCLRGFFIKRRFRSLRHKII---LLQSRARGYLARQRYQQMR 1949
RG+ ++ F + ++ ++Q YL + +Q R
Sbjct: 802 AMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWR 843
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 467 bits (1202), Expect = e-131
Identities = 275/772 (35%), Positives = 449/772 (58%), Gaps = 50/772 (6%)
Query: 1223 GVEDMTQLEDL-QETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281
GV+D LE+ E + NL+ RF NLIYTYIG +LVSVNPY+ IY + +++Y G
Sbjct: 28 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 87
Query: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLA--AMNQKR 1339
+ E PPHLFAVA+ + + +++Q ++ISGESG+GKTEATK +L++ A +R
Sbjct: 88 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 147
Query: 1340 EVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE--GGVISGAITSQYLLEKS 1397
+ ++L++ P+LE+FGNAKT+RNDNSSRFGK++++ + G + G I S YLLEKS
Sbjct: 148 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILS-YLLEKS 206
Query: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQ-EAETYYYLNQGGNCEIAGKSDADDFR 1456
R+V Q ERN+HIFY+LL G + + L+ ++Y YL +G +++ +D D++
Sbjct: 207 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 266
Query: 1457 RLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELL 1516
+ A+ V+ F+ ++ + + I+AS+LHLGN++F E + A V + +++ + LL
Sbjct: 267 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANE---ESNAQVTTENQLKYLTRLL 323
Query: 1517 QISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVS 1576
+ L++A+T + E++ +PL +E A ARDA+AK +Y+ F+WL+ ++N ++
Sbjct: 324 SVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLA 383
Query: 1577 PR-------QDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYI 1629
+ + T + +LDIYGFE NSFEQ CINY NE LQ LF ++ + EQEEY
Sbjct: 384 SKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYE 443
Query: 1630 REQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQKC------HYH 1682
E I W+ + + +N+ +L+ K GI+ ILD++C P +ATD TFL+K H H
Sbjct: 444 AEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPH 503
Query: 1683 ---HGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVV 1739
H ++ + EF + HYAG+VTY V FLDKN+D + +++ + S+ ++
Sbjct: 504 FLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIM 563
Query: 1740 AHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPN 1799
+ F S ++ + TVA +F+ SLL LVE ++ P ++RC+KPN
Sbjct: 564 SQCFD-------------RSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 610
Query: 1800 HKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDL---- 1855
K+PG F+ ++ Q++Y G+LE +R+R+ GF R ++ F+ RY L
Sbjct: 611 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGR 670
Query: 1856 PANGDMCVSVLSRLCKVMPNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCL 1913
P +G V+VL R P Y++G +K+F++ + L+ +++ +LA +Q
Sbjct: 671 PQDG---VAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLAT-KIQAAW 726
Query: 1914 RGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSR 1965
RGF +++F ++ I +QS RG L R++ + + + R L+ +V R
Sbjct: 727 RGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLR 778
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 467 bits (1202), Expect = e-131
Identities = 275/772 (35%), Positives = 449/772 (58%), Gaps = 50/772 (6%)
Query: 1223 GVEDMTQLEDL-QETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281
GV+D LE+ E + NL+ RF NLIYTYIG +LVSVNPY+ IY + +++Y G
Sbjct: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106
Query: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLA--AMNQKR 1339
+ E PPHLFAVA+ + + +++Q ++ISGESG+GKTEATK +L++ A +R
Sbjct: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166
Query: 1340 EVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE--GGVISGAITSQYLLEKS 1397
+ ++L++ P+LE+FGNAKT+RNDNSSRFGK++++ + G + G I S YLLEKS
Sbjct: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILS-YLLEKS 225
Query: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQ-EAETYYYLNQGGNCEIAGKSDADDFR 1456
R+V Q ERN+HIFY+LL G + + L+ ++Y YL +G +++ +D D++
Sbjct: 226 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 285
Query: 1457 RLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELL 1516
+ A+ V+ F+ ++ + + I+AS+LHLGN++F E + A V + +++ + LL
Sbjct: 286 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANE---ESNAQVTTENQLKYLTRLL 342
Query: 1517 QISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVS 1576
+ L++A+T + E++ +PL +E A ARDA+AK +Y+ F+WL+ ++N ++
Sbjct: 343 SVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLA 402
Query: 1577 PR-------QDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYI 1629
+ + T + +LDIYGFE NSFEQ CINY NE LQ LF ++ + EQEEY
Sbjct: 403 SKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYE 462
Query: 1630 REQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQKC------HYH 1682
E I W+ + + +N+ +L+ K GI+ ILD++C P +ATD TFL+K H H
Sbjct: 463 AEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPH 522
Query: 1683 ---HGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVV 1739
H ++ + EF + HYAG+VTY V FLDKN+D + +++ + S+ ++
Sbjct: 523 FLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIM 582
Query: 1740 AHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPN 1799
+ F S ++ + TVA +F+ SLL LVE ++ P ++RC+KPN
Sbjct: 583 SQCFD-------------RSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 629
Query: 1800 HKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDL---- 1855
K+PG F+ ++ Q++Y G+LE +R+R+ GF R ++ F+ RY L
Sbjct: 630 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGR 689
Query: 1856 PANGDMCVSVLSRLCKVMPNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCL 1913
P +G V+VL R P Y++G +K+F++ + L+ +++ +LA +Q
Sbjct: 690 PQDG---VAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLAT-KIQAAW 745
Query: 1914 RGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSR 1965
RGF +++F ++ I +QS RG L R++ + + + R L+ +V R
Sbjct: 746 RGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLR 797
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 467 bits (1202), Expect = e-131
Identities = 275/772 (35%), Positives = 449/772 (58%), Gaps = 50/772 (6%)
Query: 1223 GVEDMTQLEDL-QETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281
GV+D LE+ E + NL+ RF NLIYTYIG +LVSVNPY+ IY + +++Y G
Sbjct: 12 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 71
Query: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLA--AMNQKR 1339
+ E PPHLFAVA+ + + +++Q ++ISGESG+GKTEATK +L++ A +R
Sbjct: 72 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 131
Query: 1340 EVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE--GGVISGAITSQYLLEKS 1397
+ ++L++ P+LE+FGNAKT+RNDNSSRFGK++++ + G + G I S YLLEKS
Sbjct: 132 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILS-YLLEKS 190
Query: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQ-EAETYYYLNQGGNCEIAGKSDADDFR 1456
R+V Q ERN+HIFY+LL G + + L+ ++Y YL +G +++ +D D++
Sbjct: 191 RVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWK 250
Query: 1457 RLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELL 1516
+ A+ V+ F+ ++ + + I+AS+LHLGN++F E + A V + +++ + LL
Sbjct: 251 VVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANE---ESNAQVTTENQLKYLTRLL 307
Query: 1517 QISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVS 1576
+ L++A+T + E++ +PL +E A ARDA+AK +Y+ F+WL+ ++N ++
Sbjct: 308 SVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLA 367
Query: 1577 PR-------QDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYI 1629
+ + T + +LDIYGFE NSFEQ CINY NE LQ LF ++ + EQEEY
Sbjct: 368 SKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYE 427
Query: 1630 REQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQKC------HYH 1682
E I W+ + + +N+ +L+ K GI+ ILD++C P +ATD TFL+K H H
Sbjct: 428 AEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPH 487
Query: 1683 ---HGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVV 1739
H ++ + EF + HYAG+VTY V FLDKN+D + +++ + S+ ++
Sbjct: 488 FLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIM 547
Query: 1740 AHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPN 1799
+ F S ++ + TVA +F+ SLL LVE ++ P ++RC+KPN
Sbjct: 548 SQCFD-------------RSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPN 594
Query: 1800 HKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDL---- 1855
K+PG F+ ++ Q++Y G+LE +R+R+ GF R ++ F+ RY L
Sbjct: 595 DAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGR 654
Query: 1856 PANGDMCVSVLSRLCKVMPNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCL 1913
P +G V+VL R P Y++G +K+F++ + L+ +++ +LA +Q
Sbjct: 655 PQDG---VAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLAT-KIQAAW 710
Query: 1914 RGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSR 1965
RGF +++F ++ I +QS RG L R++ + + + R L+ +V R
Sbjct: 711 RGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLR 762
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 463 bits (1191), Expect = e-129
Identities = 284/737 (38%), Positives = 411/737 (55%), Gaps = 42/737 (5%)
Query: 1221 EDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYN 1280
+ GV+DM L + E + +NL+ RF + I+TYIGS+L+SVNP++ + ++ Y
Sbjct: 16 QSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQ 75
Query: 1281 GRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKRE 1340
G A ENPPH++A+ + + ML +NQC+IISGESG+GKT A K I+ Y++ ++ E
Sbjct: 76 GAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGE 135
Query: 1341 VMQQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKS 1397
+Q +K IL++ PLLE+FGNAKTVRN+NSSRFGK+ EI F GG G S +LLEKS
Sbjct: 136 KVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKS 195
Query: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRR 1457
R+V Q +NERN+HI+Y+LL G + RQ L + YYYLNQ ++ G D DF
Sbjct: 196 RVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFGE 255
Query: 1458 LLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQ 1517
L+AM+V+G Q + +++A ILHLGN+ F + A V S + A LL
Sbjct: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISF----CEDGNYARVESVDLLAFPAYLLG 311
Query: 1518 ISPEGLQKAITFKVTET----MREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNA 1573
I LQ+ +T + ++ E I L VE A RDA+AK LYA LF +L+ +N
Sbjct: 312 IDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINR 371
Query: 1574 LVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQI 1633
+ Q+ SI +LDIYGFE N FEQ CIN+ NE LQ +F ++ + EQEEY++E I
Sbjct: 372 AMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGI 431
Query: 1634 DWQEITFADNQPCINLI--SLKPYGILRILDDQCCFPQAT----DHTFLQKCHYHHGANP 1687
W I + +N+ +LI L P GI+ +LDD C AT D T LQK G +
Sbjct: 432 RWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHE 491
Query: 1688 LYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHA 1747
++ F I HYAGKV+Y V F ++N D + D+++L S + LF
Sbjct: 492 HFNSWS---AGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFLRMLF---- 544
Query: 1748 PQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLF 1807
P++L + + T +K ++ DLV + RC P ++RC+KPN K P +
Sbjct: 545 ----PEKLDGD----KKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDW 596
Query: 1808 EPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPA-NGD--MCVS 1864
E + V Q+ Y G+ E +R+R+ GF R F F+ RY L P GD V
Sbjct: 597 EENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILT--PETWPRWRGDERQGVQ 654
Query: 1865 VLSRLCKVMPNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRF 1922
L R + P+ Y++G +K+F+K E L+ LLE +RE + A T+Q+ R R++
Sbjct: 655 HLLRAVNMEPDQYQMGSTKVFVKNPESLF-LLEEVRERKFDGFARTIQKAWRRHVAVRKY 713
Query: 1923 RSLRHKI--ILLQSRAR 1937
+R + ILL + R
Sbjct: 714 EEMREEASNILLNKKER 730
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 460 bits (1184), Expect = e-128
Identities = 299/827 (36%), Positives = 445/827 (53%), Gaps = 49/827 (5%)
Query: 1225 EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRAL 1284
EDM +L L E +VL NL+ R+ LIYTY G V +NPY+ IY V+ Y G+
Sbjct: 108 EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
Query: 1285 GENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ- 1343
E PPH++AV A+ ML +++Q I+ +GESG+GKTE TK +++YLA + + +
Sbjct: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
Query: 1344 -------QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLE 1395
+ ++L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA YLLE
Sbjct: 228 PGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287
Query: 1396 KSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDF 1455
KSR + QAK+E ++HIFY+LL G QL+ L+ Y +L G + + + + F
Sbjct: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS--SPGQERELF 345
Query: 1456 RRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAEL 1515
+ L ++ VLGFS E+ S+ R+++++L GN+ ++ Q A++ Q + L
Sbjct: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQ--ATMPDNTAAQKLCRL 403
Query: 1516 LQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV 1575
L + +A+ + R+ + T E A A +A+AK Y LF WL+ R+N +
Sbjct: 404 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 463
Query: 1576 --SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQI 1633
SPRQ + ILDI GFE NSFEQLCINY NE LQ LFN +F EQEEY RE I
Sbjct: 464 DRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGI 523
Query: 1634 DWQEITFA-DNQPCINLIS--LKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYS 1690
W + F D QPCI+LI P G+L +LD++C FP+ATD +F++K G +P +
Sbjct: 524 PWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQ 583
Query: 1691 KPK--MPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSS--- 1745
+P+ +F++ HYAGKV Y+ +++L KN D + +V L +S R+ A ++
Sbjct: 584 RPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG 643
Query: 1746 --HAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKE 1803
Q + G R TV +++SL L+ + NP F+RC+ PNH+K
Sbjct: 644 IVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703
Query: 1804 PGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLV--ALKHDLPANGDM 1861
G EP +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L A+
Sbjct: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763
Query: 1862 CVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRR 1921
C ++ L ++ PN+YRVG SK+F + + LE R+ + ++ Q RG+ +R
Sbjct: 764 CEKMIQAL-ELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRA 822
Query: 1922 FRSLRHK---IILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQ 1978
F+ + + + ++Q YL + R+ Q R K + L+ R + Q
Sbjct: 823 FQKRQQQQSALRVMQRNCAAYL-KLRHWQWWRLFTKVKPLLQV---------TRQDEVLQ 872
Query: 1979 VEGALLWEQEELSKREVVAVGHL--------EVPAELAGLLQAVAGL 2017
L + +EL ++ VG L E A LA L+A A L
Sbjct: 873 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 919
>gi|254028267 myosin 1H [Homo sapiens]
Length = 1022
Score = 460 bits (1183), Expect = e-128
Identities = 280/774 (36%), Positives = 440/774 (56%), Gaps = 51/774 (6%)
Query: 1223 GVEDMTQLEDL-QETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281
GV+D L+ E+ + NL+ RF NLIYTYIG++LVSVNPYQ GIY Q++ Y G
Sbjct: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71
Query: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAA---MNQK 1338
E PPH++A+A+ A+ M N I+ISGESG+GKTEA+K IL Y A M Q
Sbjct: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131
Query: 1339 REVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKS 1397
++ + ++L + P+LE+FGNA+T+RNDNSSRFGK+++I F G+ G YL+EKS
Sbjct: 132 LQIARD-RLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190
Query: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQ-EAETYYYLNQGGNCEIAGKSDADDFR 1456
R+V+Q + ERN+HIFY+LLAG + L+ + + Y YL+QG + + SD +D++
Sbjct: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250
Query: 1457 RLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELL 1516
+ A V+ F+ D +++F I+AS+LHLGN+ FE+ D Q A++ EI+ +A+LL
Sbjct: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEE---DDQGCATIPDTHEIKWIAKLL 307
Query: 1517 QISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVS 1576
+ P L +A+T + E E++ PLT+E +V ARDA+AK +Y F+WL+ ++N+ +
Sbjct: 308 GVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367
Query: 1577 PRQDTLS--IAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQID 1634
+ T I +LDIYGFE N FEQ CINY NE LQ L + + EQ EY E I+
Sbjct: 368 NKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIE 427
Query: 1635 WQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQKCHYHHGANPLYSKPK 1693
W+ I + +N+ +L+ + GI+ ILD++C P ATD +FL+K G + + K
Sbjct: 428 WEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRK 487
Query: 1694 MPLP---------EFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFS 1744
+ P EF + HYAG+VTY FL+KN+D + + + ++ +S+ ++ F
Sbjct: 488 LAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECF- 546
Query: 1745 SHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEP 1804
+ + + TV +F+ SL L+E + P ++RC+KPN +KEP
Sbjct: 547 ------------LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEP 594
Query: 1805 GLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALK----HDLPANGD 1860
F+ ++ Q++Y G++E +R+R+ GF R ++ F+ RY L H PA G
Sbjct: 595 SKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEG- 653
Query: 1861 MCVSVLSRLCKVMPNMYRVGVSKLFLK--EHLY---QLLESMREHVLNLAALTLQRCLRG 1915
V L + P Y++G +K+F++ L+ E + ++ T +RCL
Sbjct: 654 --VERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLG- 710
Query: 1916 FFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYL 1969
+R + R I L++ RG LAR+ Q+ + ++ R + ++SR + L
Sbjct: 711 ---RREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPL 761
>gi|51100974 myosin ID [Homo sapiens]
Length = 1006
Score = 459 bits (1182), Expect = e-128
Identities = 274/757 (36%), Positives = 438/757 (57%), Gaps = 45/757 (5%)
Query: 1221 EDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYN 1280
E G D ++ + ++NL++RFE+ IYT+IG ++VSVNPY++ IYG + ++QY
Sbjct: 8 EFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYK 67
Query: 1281 GRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMN--QK 1338
GR L E PPHLFA+A+ A+ M ++ CI+ISGESG+GKTEA+K I++Y+AA+ +
Sbjct: 68 GRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQ 127
Query: 1339 REVMQQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLE--GGVISGAITSQYLL 1394
R ++++K +L++ +LE+FGNAKT RNDNSSRFGK+++I + G I G I + YLL
Sbjct: 128 RAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHI-NNYLL 186
Query: 1395 EKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEA-ETYYYLNQGGNCEIAGKSDAD 1453
EKSR++ Q ER++H FY+LL G Q+ ++ LQ++ +Y Y++ G + + +DA
Sbjct: 187 EKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAA 245
Query: 1454 DFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVA 1513
+FR + AM+V+GF E+ ++++ILA+ILHLGN+ K+ D + + + + + +A
Sbjct: 246 EFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNL---KFVVDG-DTPLIENGKVVSIIA 301
Query: 1514 ELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNA 1573
ELL + ++KA+ ++ T R+ I T + A RDA AK +Y LF W++TR+N
Sbjct: 302 ELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRIND 361
Query: 1574 LVSPRQ-DT------LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQE 1626
++ + DT I +LDIYGFE NSFEQ CINY NE LQ LF ++V ++EQE
Sbjct: 362 IIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQE 421
Query: 1627 EYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCC-FPQATDHTFLQKCHYHHGA 1685
EY RE I W+ I + +NQ ++L+ + GI+ ILDD C + TD FL+ + G
Sbjct: 422 EYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGK 481
Query: 1686 NPLYSKPKMPLP--------EFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTR 1737
+ +S K+ +F I+HYAG V Y V F+DKN D + QD L S
Sbjct: 482 HAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNP 541
Query: 1738 VVAHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLK 1797
V+ +++ GK S + T A F+ S++ LV+ + P ++RC+K
Sbjct: 542 VLKNMWPE----------GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIK 591
Query: 1798 PNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVAL---KHD 1854
PN KK P +F+ + Q+ Y G+LE VR+R+ GF R ++ F+ RY + HD
Sbjct: 592 PNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHD 651
Query: 1855 LPANGDMCVSVLSRLCKVMPNMYRVGVSKLFLK-EHLYQLLESMREHVLNLAALTLQRCL 1913
LP++ + ++ R C ++ G +K+F++ LE +R +L L LQ+
Sbjct: 652 LPSDKEAVKKLIER-CGFQDDV-AYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVW 709
Query: 1914 RGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRR 1950
RG + R++ + + +++ R + ++ RR
Sbjct: 710 RGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARR 746
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 162,681,875
Number of Sequences: 37866
Number of extensions: 9804953
Number of successful extensions: 89353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 339
Number of HSP's successfully gapped in prelim test: 1970
Number of HSP's that attempted gapping in prelim test: 43922
Number of HSP's gapped (non-prelim): 27219
length of query: 3530
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3408
effective length of database: 13,627,866
effective search space: 46443767328
effective search space used: 46443767328
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.