Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 239751831
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751831 PREDICTED: hypothetical protein XP_002348009 [Homo
sapiens]
(589 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239751831 PREDICTED: hypothetical protein XP_002348009 [Homo ... 1249 0.0
gi|239757324 PREDICTED: hypothetical protein XP_002345241 [Homo ... 1207 0.0
gi|239746324 PREDICTED: hypothetical protein XP_002343730 [Homo ... 688 0.0
gi|239746322 PREDICTED: hypothetical protein XP_002343729 [Homo ... 452 e-127
gi|239757352 PREDICTED: similar to LMARRLC1A [Homo sapiens] 59 1e-08
gi|239751859 PREDICTED: similar to LMARRLC1A [Homo sapiens] 58 2e-08
gi|239746350 PREDICTED: hypothetical protein XP_002343735 [Homo ... 58 2e-08
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 48 2e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 48 2e-05
gi|60097902 filaggrin [Homo sapiens] 48 3e-05
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 48 3e-05
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 44 5e-04
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 44 5e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 43 0.001
gi|62122917 filaggrin family member 2 [Homo sapiens] 42 0.002
gi|239757829 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239752340 PREDICTED: hypothetical protein XP_002348205 [Homo ... 42 0.002
gi|239746853 PREDICTED: hypothetical protein XP_002343864 [Homo ... 42 0.002
gi|57864582 hornerin [Homo sapiens] 41 0.003
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 41 0.004
gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo ... 40 0.005
gi|14249622 ajuba isoform 1 [Homo sapiens] 40 0.006
gi|11386161 alpha 2 type IX collagen [Homo sapiens] 40 0.006
gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens] 40 0.008
gi|22027605 alpha 1 type XIII collagen isoform 17 [Homo sapiens] 40 0.008
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 40 0.008
gi|239755481 PREDICTED: similar to Putative uncharacterized prot... 39 0.010
gi|239749957 PREDICTED: hypothetical protein [Homo sapiens] 39 0.010
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 39 0.010
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 39 0.010
>gi|239751831 PREDICTED: hypothetical protein XP_002348009 [Homo
sapiens]
Length = 589
Score = 1249 bits (3231), Expect = 0.0
Identities = 589/589 (100%), Positives = 589/589 (100%)
Query: 1 MILIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSE 60
MILIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSE
Sbjct: 1 MILIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSE 60
Query: 61 HQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILG 120
HQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILG
Sbjct: 61 HQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILG 120
Query: 121 AGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPES 180
AGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPES
Sbjct: 121 AGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPES 180
Query: 181 QEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ 240
QEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ
Sbjct: 181 QEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ 240
Query: 241 VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE 300
VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE
Sbjct: 241 VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE 300
Query: 301 VAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDV 360
VAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDV
Sbjct: 301 VAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDV 360
Query: 361 GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQ 420
GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQ
Sbjct: 361 GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQ 420
Query: 421 DAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQH 480
DAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQH
Sbjct: 421 DAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQH 480
Query: 481 SHQEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPR 540
SHQEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPR
Sbjct: 481 SHQEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPR 540
Query: 541 GSKVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 589
GSKVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG
Sbjct: 541 GSKVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 589
>gi|239757324 PREDICTED: hypothetical protein XP_002345241 [Homo
sapiens]
Length = 582
Score = 1207 bits (3122), Expect = 0.0
Identities = 570/587 (97%), Positives = 573/587 (97%), Gaps = 12/587 (2%)
Query: 3 LIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ 62
L++TGS + E EEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ
Sbjct: 8 LVSTGSNRRE------------EEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQ 55
Query: 63 PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG 122
PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG
Sbjct: 56 PQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG 115
Query: 123 GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE 182
GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE
Sbjct: 116 GAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQE 175
Query: 183 AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE 242
AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE
Sbjct: 176 AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE 235
Query: 243 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA 302
QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA
Sbjct: 236 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVA 295
Query: 303 VIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGK 362
VIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGK
Sbjct: 296 VIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGK 355
Query: 363 GDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDA 422
GDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDA
Sbjct: 356 GDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDA 415
Query: 423 AGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSH 482
AGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSH
Sbjct: 416 AGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSH 475
Query: 483 QEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGS 542
QEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGS
Sbjct: 476 QEDDCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGS 535
Query: 543 KVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 589
KVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG
Sbjct: 536 KVPPAQGLWFLKPQGKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 582
>gi|239746324 PREDICTED: hypothetical protein XP_002343730 [Homo
sapiens]
Length = 329
Score = 688 bits (1776), Expect = 0.0
Identities = 321/323 (99%), Positives = 321/323 (99%)
Query: 1 MILIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSE 60
MILIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSE
Sbjct: 1 MILIATGSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSE 60
Query: 61 HQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILG 120
HQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILG
Sbjct: 61 HQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILG 120
Query: 121 AGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPES 180
AGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPES
Sbjct: 121 AGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPES 180
Query: 181 QEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ 240
QEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ
Sbjct: 181 QEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ 240
Query: 241 VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE 300
VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE
Sbjct: 241 VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE 300
Query: 301 VAVIPILVADRIVPHSGSWVSPT 323
VAVIPILVADRIVPHSGSW PT
Sbjct: 301 VAVIPILVADRIVPHSGSWCEPT 323
Score = 93.2 bits (230), Expect = 6e-19
Identities = 61/169 (36%), Positives = 78/169 (46%), Gaps = 3/169 (1%)
Query: 354 VDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHV 413
V AVD G Q Q G A P P + Q+ VG + QEQDAG+H
Sbjct: 140 VQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHG 199
Query: 414 EQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPD 473
+QD+GGQ PV NG QDGQRQ +++ + QVE+P G P G HP
Sbjct: 200 QQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPG 259
Query: 474 HQGIAQHSHQED---DCKDDQGQDVWNTQRVRSFIHRGVEVQGILVIIV 519
H GIA+H HQED + Q V +HR V ++ I+V
Sbjct: 260 HHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILV 308
>gi|239746322 PREDICTED: hypothetical protein XP_002343729 [Homo
sapiens]
Length = 221
Score = 452 bits (1162), Expect = e-127
Identities = 212/213 (99%), Positives = 212/213 (99%)
Query: 377 DPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYN 436
DPGQA PSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYN
Sbjct: 9 DPGQASPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYN 68
Query: 437 GREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDVW 496
GREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDVW
Sbjct: 69 GREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDVW 128
Query: 497 NTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPAQGLWFLKPQ 556
NTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPAQGLWFLKPQ
Sbjct: 129 NTQRVRSFIHRGVEVQGILVIIVPIIRGGIIEGTHHVLVSWAPRGSKVPPAQGLWFLKPQ 188
Query: 557 GKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 589
GKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG
Sbjct: 189 GKMQGGNDRLSLWGSHWKWASIVPSRQPTEIPG 221
Score = 90.9 bits (224), Expect = 3e-18
Identities = 53/142 (37%), Positives = 70/142 (49%), Gaps = 3/142 (2%)
Query: 167 ARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQ 226
A P P + Q+ VG + QEQDAG+H +QD+GGQ PV NG Q
Sbjct: 13 ASPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQ 72
Query: 227 DGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 286
DGQRQ +++ + QVE+P G P G HP H GIA+H HQED + Q V
Sbjct: 73 DGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQED---DCKDDQGQDVWN 129
Query: 287 QAGAIQAVHRAVREVAVIPILV 308
+HR V ++ I+V
Sbjct: 130 TQRVRSFIHRGVEVQGILVIIV 151
>gi|239757352 PREDICTED: similar to LMARRLC1A [Homo sapiens]
Length = 279
Score = 58.9 bits (141), Expect = 1e-08
Identities = 36/117 (30%), Positives = 55/117 (47%)
Query: 379 GQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGR 438
GQA + VL PD + AV ++ G ++D V+ G ++ A PA+ P+
Sbjct: 134 GQAHGAVVLGPDWMQDANTAVQSNEGDQEDTSEQVDVHYGKEEFAQEPAERPMSSHGLPD 193
Query: 439 EQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDV 495
++ Q EV + QV+ DG D E HPDH+ +AQ + DCK D+
Sbjct: 194 HEEWQSGGETEVSHGQVQVTDGGDCVCHPESSHPDHKPVAQDPEDKGDCKYQISDDI 250
Score = 40.4 bits (93), Expect = 0.005
Identities = 51/197 (25%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 94 GTVAAGHGHQGPQEAKKKPD-GSHRILGAGGAAVVHHTLQPGWEVLLVQPA--------- 143
G + + G EA +PD SHR G G + + PG +V
Sbjct: 53 GPITDSNDGHGCAEANDEPDDASHRQHGNGHLYPLFRVVGPGRKVKSAGYCPRFTRYCSH 112
Query: 144 VDGGGHGEQQGQCPGCPTGHL----HPARPLNRRPPGRPESQEAEVGTESCQE---QDAG 196
+ E+Q PG P HL H A L P ++ A E QE +
Sbjct: 113 TNDNWQCEEQSHHPG-PNDHLLGQAHGAVVLG--PDWMQDANTAVQSNEGDQEDTSEQVD 169
Query: 197 IHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPS 256
+H +++ Q P RP++S G ++ Q ++ HGQV+ G S
Sbjct: 170 VHYGKEEFAQEPAE----RPMSSHGLPDHEEWQSGGETEVSHGQVQVTDGGDCVCHPESS 225
Query: 257 HPGHHGIARHPHQEDGG 273
HP H +A+ P ED G
Sbjct: 226 HPDHKPVAQDP--EDKG 240
>gi|239751859 PREDICTED: similar to LMARRLC1A [Homo sapiens]
Length = 279
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/117 (30%), Positives = 54/117 (46%)
Query: 379 GQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGR 438
GQA + VL PD + AV ++ G ++D V+ G + A PA+ P+
Sbjct: 134 GQAHGAVVLGPDWMQDANTAVQSNEGDQEDTSEQVDVHYGKDEFAQEPAERPMSSHGLPD 193
Query: 439 EQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDV 495
++ Q EV + QV+ DG D E HPDH+ +AQ + DCK D+
Sbjct: 194 HEEWQSGGETEVSHGQVQVTDGGDCVCHPESSHPDHKPVAQDPEDKGDCKYQISDDI 250
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/197 (26%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 94 GTVAAGHGHQGPQEAKKKPD-GSHRILGAGGAAVVHHTLQPGWEVLLVQPA--------- 143
G + + G EA +PD SHR G G + + PG +V
Sbjct: 53 GPITDSNDGHGCAEANDEPDDASHRQHGNGHIYPLFRVVGPGRKVKSAGYCPRFTRYCSH 112
Query: 144 VDGGGHGEQQGQCPGCPTGHL----HPARPLNRRPPGRPESQEAEVGTESCQE---QDAG 196
+ E+Q PG P HL H A L P ++ A E QE +
Sbjct: 113 TNDNWQCEEQSHHPG-PNDHLLGQAHGAVVLG--PDWMQDANTAVQSNEGDQEDTSEQVD 169
Query: 197 IHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPS 256
+H +D+ Q P RP++S G ++ Q ++ HGQV+ G S
Sbjct: 170 VHYGKDEFAQEPAE----RPMSSHGLPDHEEWQSGGETEVSHGQVQVTDGGDCVCHPESS 225
Query: 257 HPGHHGIARHPHQEDGG 273
HP H +A+ P ED G
Sbjct: 226 HPDHKPVAQDP--EDKG 240
>gi|239746350 PREDICTED: hypothetical protein XP_002343735 [Homo
sapiens]
Length = 279
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/117 (30%), Positives = 54/117 (46%)
Query: 379 GQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGR 438
GQA + VL PD + AV ++ G ++D V+ G + A PA+ P+
Sbjct: 134 GQAHGAVVLGPDWMQDANTAVQSNEGDQEDTSEQVDVHYGKDEFAQEPAERPMSSHGLPD 193
Query: 439 EQDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDV 495
++ Q EV + QV+ DG D E HPDH+ +AQ + DCK D+
Sbjct: 194 HEEWQSGGETEVSHGQVQVTDGGDCVCHPESSHPDHKPVAQDPEDKGDCKYQISDDI 250
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/197 (26%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 94 GTVAAGHGHQGPQEAKKKPD-GSHRILGAGGAAVVHHTLQPGWEVLLVQPA--------- 143
G + + G EA +PD SHR G G + + PG +V
Sbjct: 53 GPITDSNDGHGCAEANDEPDDASHRQHGNGHIYPLFRVVGPGRKVKSAGYCPRFTRYCSH 112
Query: 144 VDGGGHGEQQGQCPGCPTGHL----HPARPLNRRPPGRPESQEAEVGTESCQE---QDAG 196
+ E+Q PG P HL H A L P ++ A E QE +
Sbjct: 113 TNDNWQCEEQSHHPG-PNDHLLGQAHGAVVLG--PDWMQDANTAVQSNEGDQEDTSEQVD 169
Query: 197 IHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPS 256
+H +D+ Q P RP++S G ++ Q ++ HGQV+ G S
Sbjct: 170 VHYGKDEFAQEPAE----RPMSSHGLPDHEEWQSGGETEVSHGQVQVTDGGDCVCHPESS 225
Query: 257 HPGHHGIARHPHQEDGG 273
HP H +A+ P ED G
Sbjct: 226 HPDHKPVAQDP--EDKG 240
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 48.1 bits (113), Expect = 2e-05
Identities = 124/494 (25%), Positives = 160/494 (32%), Gaps = 106/494 (21%)
Query: 36 GKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHH-NGCAQRPAASGCPAQEG 94
G + GF PG+ G G P+ + G P P +G A P A G P +G
Sbjct: 696 GPRGERGF----PGER-GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG 750
Query: 95 TV----AAGH----------GHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLV 140
AAG G +GP+ A K DG + G G EV
Sbjct: 751 MPGERGAAGIAGPKGDRGDVGEKGPEGAPGK-DGGRGLTGPIGPPGPAGANGEKGEVGPP 809
Query: 141 QPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGT--ESCQEQDAGIH 198
PA G G PG G P P P + Q G E+ Q+ DAG
Sbjct: 810 GPAGSAGARG-----APG-ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 863
Query: 199 GQQDDGG----QRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL 254
G Q G Q PT P + G Q T G+V PG P
Sbjct: 864 GPQGPSGAPGPQGPTG--VTGPKGARG---AQGPPGATGFPGAAGRVGPPGSNGNPGPPG 918
Query: 255 PSHP-------------GHHGIARHPH-QEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE 300
P P G G A P Q G E+G DG +GA
Sbjct: 919 PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD-DGPSGAEG-------- 969
Query: 301 VAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGE-GFPQSALEALAGHHVDDGVDAAVD 359
P ++ +P + GE GFP L G + G
Sbjct: 970 -------------PPGPQGLAGQRGIVGLPGQRGERGFP-----GLPGPSGEPG------ 1005
Query: 360 VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEG- 418
QG G PG GP + P G ++ + GADG +D V+ D G
Sbjct: 1006 -----KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE 1060
Query: 419 ----GQDAAGGPAKGPVVMLYNGREQDGQRQAGEE--------VGYRQVEEPDGIDGPLG 466
G A GP P G++ D + +AG + G R ++ P G G G
Sbjct: 1061 TGAVGAPGAPGPPGSPGPAGPTGKQGD-RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1119
Query: 467 LECRHPDHQGIAQH 480
E P +G+ H
Sbjct: 1120 -EAGEPGERGLKGH 1132
Score = 40.0 bits (92), Expect = 0.006
Identities = 90/389 (23%), Positives = 114/389 (29%), Gaps = 82/389 (21%)
Query: 84 PAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPA 143
P CP +A G GP+ K +P I+G G P P
Sbjct: 81 PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPP------GPQGPAGEQGPR 134
Query: 144 VDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDD 203
D G GE+ P G P P N PPG P + Q AG ++
Sbjct: 135 GDRGDKGEKGAPGPRGRDGE--PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192
Query: 204 GGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHP-----PAGHLPSHP 258
G Q + P+ G Q G+ +PG + P P G P P
Sbjct: 193 GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP-PGKP 251
Query: 259 GHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGS 318
G G A P G ERG G GA
Sbjct: 252 GDDGEAGKP-----GKAGERGPP----GPQGA---------------------------- 274
Query: 319 WVSPTESCQHVPEEAGEGFPQS-ALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGD 377
GFP + L + GH G+D A G+ GV+ G+
Sbjct: 275 ----------------RGFPGTPGLPGVKGHRGYPGLDGAK--GEAGAPGVKGESGSPGE 316
Query: 378 PGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNG 437
G GP G + + GA G + D + G GPA GP
Sbjct: 317 NGSPGPMGPRGLPGERGRTGPAGAAGARGNDG----QPGPAGPPGPVGPAGGPGF----- 367
Query: 438 REQDGQRQAGEEVGYRQVEEPDGIDGPLG 466
G A E G P+G GP G
Sbjct: 368 ---PGAPGAKGEAGPTGARGPEGAQGPRG 393
Score = 38.9 bits (89), Expect = 0.013
Identities = 109/446 (24%), Positives = 143/446 (32%), Gaps = 75/446 (16%)
Query: 47 GPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAG--HGHQG 104
GP G RG + P G P P G P A G + G A G QG
Sbjct: 336 GPAGAAGARGNDGQPGP---AGPPGPVGPA--GGPGFPGAPGAKGEAGPTGARGPEGAQG 390
Query: 105 PQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHL 164
P+ P GS GA G PG + + P G PG P G
Sbjct: 391 PRGEPGTP-GSPGPAGASG--------NPGTDGI---PGAKGSAGAPGIAGAPGFP-GPR 437
Query: 165 HPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGH 224
P P P P+ Q E G AG G+Q G+ G
Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGI-------AGFKGEQGPKGE-------------PGPAG 477
Query: 225 CQDGQRQTAQQIRHGQVEQPGGTHP--PAGHLPSHPGHHGIARHPHQEDG-----GIQWE 277
Q ++ + G +PGG P P G + PG+ G +DG G E
Sbjct: 478 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA-PGNRGFPG----QDGLAGPKGAPGE 532
Query: 278 RGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESC--QHVPEEAGE 335
RG + + G GA R P L R + P P E G
Sbjct: 533 RGPSG-LAGPKGANGDPGRPGE-----PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 586
Query: 336 GFP--------QSALEALAGHHVDDGVDA-AVDVGKGDTQGVQLIQQQEGDPGQAGPSEV 386
P Q + G +G A + G G++ + ++G+ G AGP
Sbjct: 587 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646
Query: 387 LAPDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGRE----Q 440
P G + +Q A G G G G E + G G A P ++ G +
Sbjct: 647 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706
Query: 441 DGQRQAGEEVGYRQVEEPDGIDGPLG 466
G A G R + G DGP G
Sbjct: 707 RGSPGAQGLQGPRGLPGTPGTDGPKG 732
Score = 33.9 bits (76), Expect = 0.43
Identities = 107/431 (24%), Positives = 134/431 (31%), Gaps = 59/431 (13%)
Query: 45 PQGPGQECGVRGRHSEHQPQQVVGCPA-DKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQ 103
PQGP E G RG + + G D +P G P G P G
Sbjct: 124 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL-------- 175
Query: 104 GPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH 163
G A + G G V+ + P PA G G Q PG P G
Sbjct: 176 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN--PGEP-GE 232
Query: 164 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNG 223
+ P+ R P P + + G E+ + AG G G R P G
Sbjct: 233 PGVSGPMGPRGPPGPPGKPGDDG-EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291
Query: 224 HCQ-DGQRQTAQQIR-HGQVEQPG--GTHPPAGH--LPSHPGHHGIARHPHQEDGGIQWE 277
+ DG + A G+ PG G+ P G LP G G A G
Sbjct: 292 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA--------GAAGA 343
Query: 278 RGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGF 337
RG+ DGQ G P + P G + G
Sbjct: 344 RGN----DGQPG---------------PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG 384
Query: 338 PQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQK 397
P+ A A G T G+ + G PG AG P G Q
Sbjct: 385 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444
Query: 398 AVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQV 455
A G G GQ + G+ + E G GPA GP Q AGEE
Sbjct: 445 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA-GP---------QGAPGPAGEEGKRGAR 494
Query: 456 EEPDGIDGPLG 466
EP G+ GP+G
Sbjct: 495 GEPGGV-GPIG 504
Score = 33.9 bits (76), Expect = 0.43
Identities = 112/467 (23%), Positives = 153/467 (32%), Gaps = 74/467 (15%)
Query: 36 GKAHDEGFSPQGPGQE-----CGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCP 90
G A GF P PG + G RG P+ G P P G + P G P
Sbjct: 360 GPAGGPGF-PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA--GASGNPGTDGIP 416
Query: 91 AQEGT-----VAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVD 145
+G+ +A G GP+ P G+ LG G Q G +P +
Sbjct: 417 GAKGSAGAPGIAGAPGFPGPR-GPPGPQGATGPLGPKG--------QTG------EPGIA 461
Query: 146 G--GGHGEQQGQCPGCPTGHLHPARPLNRRP---------PGRPESQEAEVGTESCQEQD 194
G G G + P P G PA +R P P + G QD
Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 521
Query: 195 AGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL 254
G+ G + G+R + A+ G + A+ G +PG P
Sbjct: 522 -GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR----GLTGRPGDAGPQGKVG 576
Query: 255 PSH-PGHHGIARHPHQEDGGIQWERGH--AQRVDGQAGAIQAVHRAVREVAVIPILVADR 311
PS PG G P G Q RG G GA +A + +P R
Sbjct: 577 PSGAPGEDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKG--LPGAPGLR 629
Query: 312 IVP----HSGSWVSPTESCQHVPEEAGEGFP-QSALEALAGHHVDDGVDAAVDVGKGDTQ 366
+P +G+ P E +G P S + L G G+G
Sbjct: 630 GLPGKDGETGA-AGPPGPAGPAGERGEQGAPGPSGFQGLPG--------PPGPPGEGGKP 680
Query: 367 GVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGP 426
G Q + + G PG GP G + A G G + + +G AG P
Sbjct: 681 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 740
Query: 427 -AKGPVVMLYNGREQDGQRQAGE-----EVGYRQVEEPDGIDGPLGL 467
A+GP + E+ AG +VG + E G DG GL
Sbjct: 741 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 787
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 48.1 bits (113), Expect = 2e-05
Identities = 124/494 (25%), Positives = 160/494 (32%), Gaps = 106/494 (21%)
Query: 36 GKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHH-NGCAQRPAASGCPAQEG 94
G + GF PG+ G G P+ + G P P +G A P A G P +G
Sbjct: 627 GPRGERGF----PGER-GSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQG 681
Query: 95 TV----AAGH----------GHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLV 140
AAG G +GP+ A K DG + G G EV
Sbjct: 682 MPGERGAAGIAGPKGDRGDVGEKGPEGAPGK-DGGRGLTGPIGPPGPAGANGEKGEVGPP 740
Query: 141 QPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGT--ESCQEQDAGIH 198
PA G G PG G P P P + Q G E+ Q+ DAG
Sbjct: 741 GPAGSAGARG-----APG-ERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 794
Query: 199 GQQDDGG----QRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL 254
G Q G Q PT P + G Q T G+V PG P
Sbjct: 795 GPQGPSGAPGPQGPTG--VTGPKGARG---AQGPPGATGFPGAAGRVGPPGSNGNPGPPG 849
Query: 255 PSHP-------------GHHGIARHPH-QEDGGIQWERGHAQRVDGQAGAIQAVHRAVRE 300
P P G G A P Q G E+G DG +GA
Sbjct: 850 PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD-DGPSGAEG-------- 900
Query: 301 VAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGE-GFPQSALEALAGHHVDDGVDAAVD 359
P ++ +P + GE GFP L G + G
Sbjct: 901 -------------PPGPQGLAGQRGIVGLPGQRGERGFP-----GLPGPSGEPG------ 936
Query: 360 VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEG- 418
QG G PG GP + P G ++ + GADG +D V+ D G
Sbjct: 937 -----KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE 991
Query: 419 ----GQDAAGGPAKGPVVMLYNGREQDGQRQAGEE--------VGYRQVEEPDGIDGPLG 466
G A GP P G++ D + +AG + G R ++ P G G G
Sbjct: 992 TGAVGAPGAPGPPGSPGPAGPTGKQGD-RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1050
Query: 467 LECRHPDHQGIAQH 480
E P +G+ H
Sbjct: 1051 -EAGEPGERGLKGH 1063
Score = 38.9 bits (89), Expect = 0.013
Identities = 109/446 (24%), Positives = 143/446 (32%), Gaps = 75/446 (16%)
Query: 47 GPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAG--HGHQG 104
GP G RG + P G P P G P A G + G A G QG
Sbjct: 267 GPAGAAGARGNDGQPGP---AGPPGPVGPA--GGPGFPGAPGAKGEAGPTGARGPEGAQG 321
Query: 105 PQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHL 164
P+ P GS GA G PG + + P G PG P G
Sbjct: 322 PRGEPGTP-GSPGPAGASG--------NPGTDGI---PGAKGSAGAPGIAGAPGFP-GPR 368
Query: 165 HPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGH 224
P P P P+ Q E G AG G+Q G+ G
Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGI-------AGFKGEQGPKGE-------------PGPAG 408
Query: 225 CQDGQRQTAQQIRHGQVEQPGGTHP--PAGHLPSHPGHHGIARHPHQEDG-----GIQWE 277
Q ++ + G +PGG P P G + PG+ G +DG G E
Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA-PGNRGFPG----QDGLAGPKGAPGE 463
Query: 278 RGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESC--QHVPEEAGE 335
RG + + G GA R P L R + P P E G
Sbjct: 464 RGPSG-LAGPKGANGDPGRPGE-----PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR 517
Query: 336 GFP--------QSALEALAGHHVDDGVDA-AVDVGKGDTQGVQLIQQQEGDPGQAGPSEV 386
P Q + G +G A + G G++ + ++G+ G AGP
Sbjct: 518 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577
Query: 387 LAPDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGRE----Q 440
P G + +Q A G G G G E + G G A P ++ G +
Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637
Query: 441 DGQRQAGEEVGYRQVEEPDGIDGPLG 466
G A G R + G DGP G
Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKG 663
Score = 35.8 bits (81), Expect = 0.11
Identities = 36/136 (26%), Positives = 48/136 (35%), Gaps = 15/136 (11%)
Query: 332 EAGEGFPQS-ALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPD 390
+ GFP + L + GH G+D A G+ GV+ G+ G GP
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAK--GEAGAPGVKGESGSPGENGSPGPMGPRGLP 260
Query: 391 GFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEV 450
G + + GA G + D + G GPA GP G A E
Sbjct: 261 GERGRTGPAGAAGARGNDG----QPGPAGPPGPVGPAGGPGF--------PGAPGAKGEA 308
Query: 451 GYRQVEEPDGIDGPLG 466
G P+G GP G
Sbjct: 309 GPTGARGPEGAQGPRG 324
Score = 33.9 bits (76), Expect = 0.43
Identities = 107/431 (24%), Positives = 134/431 (31%), Gaps = 59/431 (13%)
Query: 45 PQGPGQECGVRGRHSEHQPQQVVGCPA-DKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQ 103
PQGP E G RG + + G D +P G P G P G
Sbjct: 55 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGL-------- 106
Query: 104 GPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH 163
G A + G G V+ + P PA G G Q PG P G
Sbjct: 107 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN--PGEP-GE 163
Query: 164 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNG 223
+ P+ R P P + + G E+ + AG G G R P G
Sbjct: 164 PGVSGPMGPRGPPGPPGKPGDDG-EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222
Query: 224 HCQ-DGQRQTAQQIR-HGQVEQPG--GTHPPAGH--LPSHPGHHGIARHPHQEDGGIQWE 277
+ DG + A G+ PG G+ P G LP G G A G
Sbjct: 223 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA--------GAAGA 274
Query: 278 RGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGF 337
RG+ DGQ G P + P G + G
Sbjct: 275 RGN----DGQPG---------------PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG 315
Query: 338 PQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQK 397
P+ A A G T G+ + G PG AG P G Q
Sbjct: 316 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 375
Query: 398 AVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQV 455
A G G GQ + G+ + E G GPA GP Q AGEE
Sbjct: 376 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA-GP---------QGAPGPAGEEGKRGAR 425
Query: 456 EEPDGIDGPLG 466
EP G+ GP+G
Sbjct: 426 GEPGGV-GPIG 435
Score = 33.9 bits (76), Expect = 0.43
Identities = 112/467 (23%), Positives = 153/467 (32%), Gaps = 74/467 (15%)
Query: 36 GKAHDEGFSPQGPGQE-----CGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCP 90
G A GF P PG + G RG P+ G P P G + P G P
Sbjct: 291 GPAGGPGF-PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA--GASGNPGTDGIP 347
Query: 91 AQEGT-----VAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVD 145
+G+ +A G GP+ P G+ LG G Q G +P +
Sbjct: 348 GAKGSAGAPGIAGAPGFPGPR-GPPGPQGATGPLGPKG--------QTG------EPGIA 392
Query: 146 G--GGHGEQQGQCPGCPTGHLHPARPLNRRP---------PGRPESQEAEVGTESCQEQD 194
G G G + P P G PA +R P P + G QD
Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452
Query: 195 AGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL 254
G+ G + G+R + A+ G + A+ G +PG P
Sbjct: 453 -GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR----GLTGRPGDAGPQGKVG 507
Query: 255 PSH-PGHHGIARHPHQEDGGIQWERGH--AQRVDGQAGAIQAVHRAVREVAVIPILVADR 311
PS PG G P G Q RG G GA +A + +P R
Sbjct: 508 PSGAPGEDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKG--LPGAPGLR 560
Query: 312 IVP----HSGSWVSPTESCQHVPEEAGEGFP-QSALEALAGHHVDDGVDAAVDVGKGDTQ 366
+P +G+ P E +G P S + L G G+G
Sbjct: 561 GLPGKDGETGA-AGPPGPAGPAGERGEQGAPGPSGFQGLPG--------PPGPPGEGGKP 611
Query: 367 GVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGP 426
G Q + + G PG GP G + A G G + + +G AG P
Sbjct: 612 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 671
Query: 427 -AKGPVVMLYNGREQDGQRQAGE-----EVGYRQVEEPDGIDGPLGL 467
A+GP + E+ AG +VG + E G DG GL
Sbjct: 672 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718
Score = 29.6 bits (65), Expect = 8.1
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 362 KGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQD 421
KG+ ++ I +G PG GP+ P G + + GA G + +D + G
Sbjct: 37 KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG 96
Query: 422 AAGGPAKGPVVMLYNGREQDGQRQAG--EEVGYRQVEEPDGIDGPLG 466
G P GP + G Q G E+ G Q+ G GP+G
Sbjct: 97 PPGPP--GPPGL---GGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 47.8 bits (112), Expect = 3e-05
Identities = 114/523 (21%), Positives = 163/523 (31%), Gaps = 137/523 (26%)
Query: 48 PGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQE 107
PG G GR H Q V + H+G S +G A HGH G +
Sbjct: 2466 PGSSSG--GRQGSHYEQLV------DRSGHSGSHHSHTTS-----QGRSDASHGHSGSRS 2512
Query: 108 AKKKP-------DGS------HRILGAGGAAVVHHTLQPG----------WEVLLVQPAV 144
A ++ DGS H + + H + G W Q +
Sbjct: 2513 ASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDS- 2571
Query: 145 DGGGHGEQQGQCPGCPTGHLHPA-----RPLNRRPPGRPESQEAEVGTESCQEQDAGIHG 199
D GH E + G + + H + R +R P E + + Q H
Sbjct: 2572 DSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHT 2631
Query: 200 QQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPG 259
Q GGQ ++H R +S G H Q Q+A RH G H A G
Sbjct: 2632 QTSSGGQAASSHEQAR--SSAGERHGSHHQ-QSADSSRHS-----GIGHGQASSAVRDSG 2683
Query: 260 HHGIA------RHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIV 313
H G + H ED Q H GQAG+ Q H+ +
Sbjct: 2684 HRGYSGSQASDNEGHSEDSDTQSVSAH-----GQAGSHQQSHQESARGR------SGETS 2732
Query: 314 PHSGS----------------WVSPT-------------ESCQHVPEEAGE----GFPQS 340
HSGS W P+ +S +H + G+ G P S
Sbjct: 2733 GHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGS 2792
Query: 341 ALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGP--------SEVLAPDGF 392
+ G+H + VD++ G + + + GQ+G +E + DG
Sbjct: 2793 SRGGRQGYHHEHSVDSSGHSGSHHSHTTSQ-GRSDASRGQSGSRSASRTTRNEEQSGDGS 2851
Query: 393 KHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGY 452
+H G + +A H + Q A G ++G R+ G V
Sbjct: 2852 RH-------SGSRHHEASTHADISRHSQ-AVQGQSEG----------SRRSRRQGSSVSQ 2893
Query: 453 RQVEEPDGIDGPLGLECRHPDHQGIAQ----------HSHQED 485
E D +H G AQ SHQED
Sbjct: 2894 DSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQED 2936
Score = 46.6 bits (109), Expect = 6e-05
Identities = 74/314 (23%), Positives = 99/314 (31%), Gaps = 40/314 (12%)
Query: 9 EKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQG-----PGQECGVRGRHSEHQP 63
E+ E+T G S G + + H Q PG G GR HQ
Sbjct: 2098 EQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRG--GRQGSHQ- 2154
Query: 64 QQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA------------GHGHQGPQ--EAK 109
+Q V HH+ + + Q G+ +A G H G EA
Sbjct: 2155 EQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEAS 2214
Query: 110 KKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLH---- 165
D S L G + T +P V D GH E + G + + H
Sbjct: 2215 SWADSSRHSLVGQGQSSGPRTSRPRGSS--VSQDSDSEGHSEDSERRSGSASRNHHGSAQ 2272
Query: 166 -PARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAST--GN 222
+R +R P E + + Q H + GGQ ++H R A G+
Sbjct: 2273 EQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGS 2332
Query: 223 GHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQ 282
H Q I HGQ +GH S G H ED Q H
Sbjct: 2333 HHQQSADSSRHSGIGHGQA---SSAVRDSGHRGS-SGSQASDSEGHSEDSDTQSVSAH-- 2386
Query: 283 RVDGQAGAIQAVHR 296
GQAG Q H+
Sbjct: 2387 ---GQAGPHQQSHQ 2397
Score = 42.4 bits (98), Expect = 0.001
Identities = 71/315 (22%), Positives = 97/315 (30%), Gaps = 42/315 (13%)
Query: 9 EKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQG-----PGQECGVRGRHSEHQP 63
E+ E+ G S GR + + H Q PG RGR H
Sbjct: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR--RGRQGSHY- 3450
Query: 64 QQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAG--------------HGHQGPQEAK 109
+Q V HH+ + + Q G+ +A H EA
Sbjct: 3451 EQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEAS 3510
Query: 110 KKPDGS-HRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH----- 163
+ D S H G G +A + G V D GH E + G + +
Sbjct: 3511 TQADSSRHSQSGQGQSAGPRTSRNQGSSV---SQDSDSQGHSEDSERWSGSASRNHRGSA 3567
Query: 164 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAST--G 221
+R +R P E + + Q H + GGQ ++H R A G
Sbjct: 3568 QEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHG 3627
Query: 222 NGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHA 281
+ H Q I HGQ +GH S G H ED Q H
Sbjct: 3628 SHHQQSADSSRHSGIGHGQA---SSAVRDSGHRGS-SGSQASDSEGHSEDSDTQSVSAH- 3682
Query: 282 QRVDGQAGAIQAVHR 296
GQAG Q H+
Sbjct: 3683 ----GQAGPHQQSHQ 3693
Score = 40.4 bits (93), Expect = 0.005
Identities = 66/275 (24%), Positives = 90/275 (32%), Gaps = 45/275 (16%)
Query: 48 PGQECGVR-GRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA-------- 98
PG G R G H EH V HH+ + + Q G+ +A
Sbjct: 2790 PGSSRGGRQGYHHEHS----VDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 2845
Query: 99 ----GHGHQGPQ--EAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQ 152
G H G + EA D S G + + + + V D GH E
Sbjct: 2846 QSGDGSRHSGSRHHEASTHADISRHSQAVQGQS--EGSRRSRRQGSSVSQDSDSEGHSED 2903
Query: 153 QGQCPGCPTGHLHPA-----RPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 207
+ G + + H + R +R P E + + Q H Q GGQ
Sbjct: 2904 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQA 2963
Query: 208 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIA--- 264
++H R +S G H Q Q+A RH G H A GH G +
Sbjct: 2964 ASSHEQAR--SSAGERHGSHHQ-QSADSSRHS-----GIGHGQASSAVRDSGHRGYSGSQ 3015
Query: 265 ---RHPHQEDGGIQWERGHAQRVDGQAGAIQAVHR 296
H ED Q H GQAG+ Q H+
Sbjct: 3016 ASDNEGHSEDSDTQSVSAH-----GQAGSHQQSHQ 3045
Score = 38.5 bits (88), Expect = 0.017
Identities = 86/409 (21%), Positives = 130/409 (31%), Gaps = 67/409 (16%)
Query: 48 PGQECGVR-GRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQ 106
PG G R G H EH V HH+ + + Q G+ +A + +
Sbjct: 3114 PGSSRGGRQGYHHEHS----VDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEE 3169
Query: 107 EAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHP 166
++ D S + HH ++ AV G G ++ + G
Sbjct: 3170 QSG---DSSRHSVSR------HHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQ--- 3217
Query: 167 ARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQ 226
+ G E E G+ S + + Q G + P +H R G+GH
Sbjct: 3218 ----DSDSEGHSEDSERWSGSAS-RNHRGSVQEQSRHGSRHPRSHHEDR----AGHGHSA 3268
Query: 227 DGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 286
D RQ+ RH + G S PG +RH D H+ G
Sbjct: 3269 DRSRQSGT--RHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS-----RHSGIPRG 3321
Query: 287 QAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSAL-EAL 345
QA + AVR+ R SGS S +E + E QS
Sbjct: 3322 QASS------AVRD---------SRHWGSSGSQASDSEG------HSEESDTQSVSGHGQ 3360
Query: 346 AGHHVDDGVDAAVD--VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG 403
AG H ++A D G+ G L Q + ++ G + G+
Sbjct: 3361 AGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTG-----RRQGSHH 3415
Query: 404 GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGY 452
Q +D+ H EG G P GR+ Q+ + G+
Sbjct: 3416 EQARDSSRHSASQEGQDTIRGHPGSS-----RRGRQGSHYEQSVDRSGH 3459
Score = 36.6 bits (83), Expect = 0.066
Identities = 97/515 (18%), Positives = 156/515 (30%), Gaps = 105/515 (20%)
Query: 48 PGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA--------- 98
PG G GR H +Q V HH+ + + Q G+ +A
Sbjct: 520 PGSSRG--GRQGSHH-EQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQ 576
Query: 99 ---GHGHQGPQ--EAKKKPDGS-HRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQ 152
G H G + EA + D S H +G G ++ + G V D GH E
Sbjct: 577 SGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSV---SQDSDSQGHSED 633
Query: 153 QGQCPGCPTGHLH-----PARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 207
+ G + + H +R +R P E + + + H Q GQ
Sbjct: 634 SERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQA 693
Query: 208 PTAHCTIRPVAS-------------------TGNGHCQDGQRQTAQQIRHGQVEQPGGTH 248
++H R A TG+G R + + G H
Sbjct: 694 ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGH 753
Query: 249 PPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILV 308
S GH + GH Q+ ++ ++ R+ R + + +
Sbjct: 754 SEDSDTQSVSGH---------------GQAGHHQQSHQESARDRSGERSRRSGSFLYQVS 798
Query: 309 ADRIVPHSGSWVSPT-------------ESCQHVPEEAGE----GFPQSALEALAGHHVD 351
+ S W P+ ++ +H + G+ G P S+ G H +
Sbjct: 799 THKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHE 858
Query: 352 DGVDAAVDVGK--GDTQGVQLIQQQEGDPGQAGPSEVLAPD----------GFKHQQKAV 399
VD + G T G G S + G +H + +
Sbjct: 859 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASS 918
Query: 400 GADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAG----EEVGYRQV 455
AD + AG Q EG + + + G +D +R +G G Q
Sbjct: 919 HADISRHSQAG--QGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQE 976
Query: 456 EEPDGIDGPLGLECRHP--DHQGIAQHSHQEDDCK 488
+ G RHP H+ A H H D +
Sbjct: 977 QSRHG--------SRHPRSHHEDRAGHGHSADSSR 1003
Score = 36.6 bits (83), Expect = 0.066
Identities = 62/264 (23%), Positives = 88/264 (33%), Gaps = 35/264 (13%)
Query: 55 RGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA------------GHGH 102
RGR H +Q V HH+ + + Q G+ +A G H
Sbjct: 850 RGRQGSHH-EQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRH 908
Query: 103 QGPQ--EAKKKPDGS-HRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGC 159
G + EA D S H G G + + + G V D GH E + G
Sbjct: 909 SGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSV---SQDSDSEGHSEDSERWSGS 965
Query: 160 PTGH-----LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTI 214
+ + +R +R P E + + Q H + GGQ ++H
Sbjct: 966 ASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQA 1025
Query: 215 RPVASTGNGHCQDGQRQTAQQIRHGQV--EQPGGTHPPAGHLPSHPGHHGIARHPHQEDG 272
R +S G H Q Q+A RH + Q +GH S G H E+
Sbjct: 1026 R--SSPGERHGSRHQ-QSADSSRHSGIPRRQASSAVRDSGHWGS-SGSQASDSEGHSEES 1081
Query: 273 GIQWERGHAQRVDGQAGAIQAVHR 296
Q GH GQ G Q H+
Sbjct: 1082 DTQSVSGH-----GQDGPHQQSHQ 1100
Score = 32.7 bits (73), Expect = 0.96
Identities = 88/437 (20%), Positives = 128/437 (29%), Gaps = 83/437 (18%)
Query: 28 GIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAAS 87
GI + D G Q G HSE Q V PH + + +A
Sbjct: 1372 GIGHRQASSAVRDSGHRGSSGSQVTNSEG-HSEDSDTQSVSAHGQAGPHQQ--SHKESAR 1428
Query: 88 GCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGA----------AVVHHTLQPGWEV 137
G + + +Q + + GG + H Q G +
Sbjct: 1429 GQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDT 1488
Query: 138 LLVQPAVDGGG----HGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQ 193
+ P GG + EQ G +G+ H + P GR ++ + G S Q
Sbjct: 1489 IRGHPGSSRGGRQGSYHEQSVDRSG-HSGYHHS----HTTPQGRSDASHGQSGPRSASRQ 1543
Query: 194 DAGIHGQQDDGGQRPTAHCTIRPVASTGNG-HCQDGQRQTA-QQIRHGQVEQPGGTHPPA 251
+ +Q G R + P G+ H Q GQ ++A + Q
Sbjct: 1544 TR--NEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSE 1601
Query: 252 GHLPSHP--------GHHGIARHP----------HQEDGGIQWERGHAQRVDGQAGAIQA 293
GH H+G AR HQED GH+ Q+G A
Sbjct: 1602 GHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRA---SHGHSAESSRQSGTRHA 1658
Query: 294 VHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVP-EEAGEGFPQSALEALAGHHVDD 352
+ G S E + P E G QSA
Sbjct: 1659 ETSS------------------GGQAASSQEQARSSPGERHGSRHQQSA----------- 1689
Query: 353 GVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVH 412
D++ D G G Q ++ GD G G S A D H +++ AG H
Sbjct: 1690 --DSSTDSGTGRRQDSSVV----GDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPH 1743
Query: 413 VEQDEGGQDAAGGPAKG 429
+ + G G
Sbjct: 1744 QQSHQESTRGQSGERSG 1760
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 47.8 bits (112), Expect = 3e-05
Identities = 111/465 (23%), Positives = 159/465 (34%), Gaps = 83/465 (17%)
Query: 35 EGKAHDEGFSPQ-GPGQECGVRGRHSEHQPQQVVGCP----------ADKKPHHNGCAQR 83
+G+ + G Q GP + G+ GR PQ G AD +P G A
Sbjct: 1256 KGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGN 1315
Query: 84 PAASGCPAQEGTVA-----AGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVL 138
P G P +G+ G +GP+ K +P +++G G + PG
Sbjct: 1316 PGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG---- 1371
Query: 139 LVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIH 198
P+ G G P P G P + R E G + G+
Sbjct: 1372 ---PSGPPGPRGPLGDPGPRGPPG--LPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLP 1426
Query: 199 GQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPG--GTHPPAGHLPS 256
G G + PV G + G++ ++ G QPG G P G P
Sbjct: 1427 GLPGSPGPQ-------GPVGPPG----KKGEKGDSEDGAPGLPGQPGSPGEQGPRGP-PG 1474
Query: 257 HPGHHGIARHPHQ-EDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPH 315
G G P + G + ERG G AG+ R + VA P P
Sbjct: 1475 AIGPKGDRGFPGPLGEAGEKGERG----PPGPAGS-----RGLPGVAGRPGAKGPEGPP- 1524
Query: 316 SGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQE 375
PT E G P A+AG + G DVG +G +Q +
Sbjct: 1525 -----GPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG-----DVGPAGPRGATGVQGER 1574
Query: 376 GDPGQAGPSEVLAPDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVM 433
G PG P + P G + +G G G D+G E+ + G+ GP GP
Sbjct: 1575 GPPGLVLPGDP-GPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV-GP--- 1629
Query: 434 LYNGREQDGQ-RQAGEE-----------VGYRQVEEPDGIDGPLG 466
R +DG+ + G+E G R + G+ GP+G
Sbjct: 1630 ----RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVG 1670
Score = 41.6 bits (96), Expect = 0.002
Identities = 112/473 (23%), Positives = 146/473 (30%), Gaps = 70/473 (14%)
Query: 45 PQGPGQECGVRGRHSEH-QPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQ 103
P+G E G RG E P QV+G P G P SG P G + G +
Sbjct: 1333 PRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKG---DPGPSGPPGPRGPLG-DPGPR 1388
Query: 104 GP-------QEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG--------GG 148
GP + K G G G + +PG L P G G
Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPG--EPGLPGLPGSPGPQGPVGPPGKKGE 1446
Query: 149 HGEQQGQCPGCPTGHLHPARPLNRRPPGR--PESQEAEVGTESCQEQDAGIHGQQDDGGQ 206
G+ + PG P P R PPG P+ G + + G G G
Sbjct: 1447 KGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG-EAGEKGERGPPGPAGS 1505
Query: 207 RPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHG---- 262
R RP A G RQ G+ +PG PA P+ G G
Sbjct: 1506 RGLPGVAGRPGAKGPEGPPGPTGRQ-------GEKGEPGRPGDPAVVGPAVAGPKGEKGD 1558
Query: 263 IARHPHQEDGGIQWERGHAQRV----------DGQAGAIQAVHRAVREV-AVIPILVADR 311
+ + G+Q ERG V G G I RA + P D
Sbjct: 1559 VGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDP 1618
Query: 312 IVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDV----------- 360
P V P V E+ EG P L G + G+ A V
Sbjct: 1619 GRPGPPGPVGPRGRDGEVGEKGDEGPPGDP--GLPGKAGERGLRGAPGVRGPVGEKGDQG 1676
Query: 361 -----GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQ 415
G+ + G + G+PG GP L G ++K D GQE G
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRG----- 1731
Query: 416 DEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLE 468
+G G P + + G G + P G+DG GL+
Sbjct: 1732 PKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784
Score = 38.5 bits (88), Expect = 0.017
Identities = 116/475 (24%), Positives = 160/475 (33%), Gaps = 64/475 (13%)
Query: 35 EGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKK--PHHNGCAQRPAASGCPAQ 92
+G EG P G E G++G + PQ G ++ P +G A P G P
Sbjct: 1987 QGPPGKEG--PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044
Query: 93 EGTVAAGHGHQGP--QEAKKKPDGSHRILGAGGAAVVHHTL----QPGWEVLLVQPAVDG 146
G A G G G + ++ G G G + T PG +V + +P G
Sbjct: 2045 PGR-AGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEP---G 2100
Query: 147 GGHGEQQGQCPGCPTGHLHPARPLNRRPPGRP-----ESQEAEVGTESCQEQDAGIHGQQ 201
G +QG PG P ++ P G + E G Q+ + G+ G++
Sbjct: 2101 PGLSGEQGP-PGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG-QDGNPGLPGER 2158
Query: 202 DDGGQ--RPTAHCTIRPVASTGNGHCQDGQR-------QTAQQIRHGQVEQPGGTHPP-- 250
G +P P G GH G Q G +PG T PP
Sbjct: 2159 GMAGPEGKPGLQGPRGPPGPVG-GHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGR 2217
Query: 251 -------AGHLPSHPGHHGIARHPHQEDGGIQWERGH-----------AQRVDGQAGAIQ 292
A LP PG G+ Q G+ + G A DG G+
Sbjct: 2218 GLTGPTGAVGLPGPPGPSGLVGP--QGSPGLPGQVGETGKPGAPGRDGASGKDGDRGS-- 2273
Query: 293 AVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGE-GFPQSALEALAGHHVD 351
V +P V + P G +P ++ +P GE G P L G
Sbjct: 2274 ---PGVPGSPGLPGPVGPKGEP--GPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGA 2328
Query: 352 DGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGV 411
G D + +G+ +G + GDPG+ G P GFK VG G
Sbjct: 2329 KG-DRGLPGPRGE-KGEAGRAGEPGDPGEDGQKGAPGPKGFK-GDPGVGVPGSPGPPGPP 2385
Query: 412 HVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 466
V+ D G G P R + GQ E G +GI GPLG
Sbjct: 2386 GVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440
Score = 32.7 bits (73), Expect = 0.96
Identities = 104/453 (22%), Positives = 139/453 (30%), Gaps = 100/453 (22%)
Query: 46 QGPGQECGVRGRHSEHQPQQVVGCPADKKPHH-NGCAQRPAASGCPAQEGTVAAGHGHQG 104
QGP G G H + P G P +G P +G P G G G
Sbjct: 2170 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPP--------GRGLTG 2221
Query: 105 PQEAK--KKPDGSHRILGAGGA----AVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPG 158
P A P G ++G G+ V T +PG P DG + PG
Sbjct: 2222 PTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPG------APGRDGASGKDGDRGSPG 2275
Query: 159 CP--TGHLHPARPLNRRPP------------------GRPESQEAEVGTESCQEQDAGIH 198
P G P P P G P ++ E + D G+
Sbjct: 2276 VPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLP 2335
Query: 199 GQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGH----L 254
G + + G+ A P G G + G PG PP L
Sbjct: 2336 GPRGEKGEAGRAGEPGDPGEDGQKG--APGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL 2393
Query: 255 PSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVP 314
P PG G+ P Q G + E G G +G RE P+
Sbjct: 2394 PGLPGAPGVVGFPGQT--GPRGEMGQP----GPSGERGLAGPPGREGIPGPL-------- 2439
Query: 315 HSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQ 374
P G P A L G D GV G+ G I+ +
Sbjct: 2440 -------------GPPGPPGSVGPPGA-SGLKGDKGDPGVGLPGPRGERGEPG---IRGE 2482
Query: 375 EGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAG-VHVEQDEGGQDAAGGPAKGPVVM 433
+G PGQ GP + P G + ++ G++ D G ++ D+G GP
Sbjct: 2483 DGRPGQEGPRGLTGPPGSRGER-------GEKGDVGSAGLKGDKGDSAVILGP------- 2528
Query: 434 LYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 466
G R A ++G R DG GP G
Sbjct: 2529 -------PGPRGAKGDMGERGPRGLDGDKGPRG 2554
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 43.5 bits (101), Expect = 5e-04
Identities = 110/440 (25%), Positives = 138/440 (31%), Gaps = 80/440 (18%)
Query: 45 PQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHN-GCAQRPAASGCPAQEGTVAAGHGHQ 103
P GP E G G VG + N G P +G P ++G +A GHG
Sbjct: 682 PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKG-MAGGHGPD 740
Query: 104 GPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG--GGHGEQQGQCPGCPT 161
GP+ P G+ G G + PG + P G GG GE+ +
Sbjct: 741 GPK-GSPGPSGTPGDTGPPGLQGM-----PGERGIAGTPGPKGDRGGIGEKGAEGTAGND 794
Query: 162 GHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTG 221
G PL P P ++ E G G G + + G R P + G
Sbjct: 795 GARGLPGPLGPPGPAGPTGEKGEPGPRGL----VGPPGSRGNPGSRGENG----PTGAVG 846
Query: 222 NGHCQDGQRQTAQQIRHGQVEQPG--GTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERG 279
Q Q + G+ Q G G+ P G L PG HG P G++ RG
Sbjct: 847 FAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQG-LAGSPGPHGPNGVP-----GLKGGRG 900
Query: 280 HAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQ 339
G GA P S V P P AG P
Sbjct: 901 ----TQGPPGATG--------------------FPGSAGRVGP-------PGPAGAPGPA 929
Query: 340 SAL-----EALAGHHVDDGVDAAV-DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFK 393
L E G D G V D G G + G+ GQ GP P G
Sbjct: 930 GPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTT 989
Query: 394 HQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQD-------GQRQA 446
Q+ VG G ++ E G GPA P + G D G +
Sbjct: 990 GQRGIVGMPG----------QRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGS 1039
Query: 447 GEEVGYRQVEEPDGIDGPLG 466
VG E P G DG G
Sbjct: 1040 NGPVGEPGPEGPAGNDGTPG 1059
Score = 42.0 bits (97), Expect = 0.002
Identities = 101/402 (25%), Positives = 126/402 (31%), Gaps = 63/402 (15%)
Query: 46 QGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGH-GHQG 104
QGP E G +GR PQ + G P G +P A G P GH H G
Sbjct: 140 QGPRGERGPKGRPGPRGPQGIDGEP--------GVPGQPGAPGPP--------GHPSHPG 183
Query: 105 PQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGH- 163
P + L L PG V V P G G+Q G P P G
Sbjct: 184 PDGLSRPFSAQMAGLDEKSGLGSQVGLMPG-SVGPVGPRGPQGLQGQQGGAGPTGPPGEP 242
Query: 164 --LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTG 221
P P+ R P P + E G E + + G G G R P
Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDG-EPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301
Query: 222 NGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGH- 280
GH + + + G + G T P P P G+ ERG
Sbjct: 302 RGH-KGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGP-------------RGMPGERGRL 347
Query: 281 -AQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQ 339
Q GQ GA + P + +P S + P GE P
Sbjct: 348 GPQGAPGQRGA--------HGMPGKPGPMGPLGIPGSSGFPGN-------PGMKGEAGPT 392
Query: 340 SAL--EALAGHHVDDGVDAAVD----VGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFK 393
A E G + G V G T G + G PG +GP P G
Sbjct: 393 GARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSP 452
Query: 394 HQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGP--AKGPV 431
Q + G G GQ D GV + E G GP +GP+
Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPI 494
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 43.5 bits (101), Expect = 5e-04
Identities = 104/417 (24%), Positives = 136/417 (32%), Gaps = 81/417 (19%)
Query: 67 VGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAV 126
+G P D P G +P A G P G + G +GP P G+ + G
Sbjct: 915 IGPPGDNGPE--GMKGKPGARGLPGPRGQLGP-EGDEGPMG----PPGAPGLEG------ 961
Query: 127 VHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVG 186
QPG + +P +DG GE PG P RP P ++ +G
Sbjct: 962 -----QPGRKGFPGRPGLDGV-KGE-----PG------DPGRP-------GPVGEQGFMG 997
Query: 187 TESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGG 246
+ GI G++ D G P S G+ G G +PG
Sbjct: 998 FIGLVGEP-GIVGEKGDRGMMGPPGVP-GPKGSMGHPGMPGGM---------GTPGEPGP 1046
Query: 247 THPPAGHLPSHPGHHGIA--RHPHQEDG-----------GIQWERGHAQRVDGQAGAIQA 293
PP P PG G R P DG G +G R Q A +
Sbjct: 1047 QGPPGSRGP--PGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGER 1104
Query: 294 VHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPE----EAGEGFPQSALEALAGHH 349
H R IP G+ P E P+ GE P+ A+
Sbjct: 1105 GHLGSRGFPGIPGPSGP-----PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPG 1159
Query: 350 VDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDA 409
+ D+G T G Q + Q G+PG G S + PDG K D G
Sbjct: 1160 LPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLK-------GDRGDPGPD 1212
Query: 410 GVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 466
G H E+ + G GP P V G E +Q E G + G G LG
Sbjct: 1213 GEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQG--EKGRTGAKGAKGYQGQLG 1267
Score = 36.6 bits (83), Expect = 0.066
Identities = 116/460 (25%), Positives = 151/460 (32%), Gaps = 98/460 (21%)
Query: 45 PQGPGQECGVRGRHSEHQPQQVVGCP-----ADKKPH--HNGCAQRPAASGCPAQEGTVA 97
P GP E G RG PQ G P A ++ H G P SG P +G +
Sbjct: 1070 PDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKG-LP 1128
Query: 98 AGHGHQGPQE--------AKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG--G 147
G QGPQ K P G+ G G A + L P L P G G
Sbjct: 1129 GEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGP-----LGTPGEQGLIG 1183
Query: 148 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDA--------GIHG 199
GE + P G +R PG P+ + E G E +D G+ G
Sbjct: 1184 QRGEPGLEGDSGPMGP--DGLKGDRGDPG-PDGEHGEKGQEGLMGEDGPPGPPGVTGVRG 1240
Query: 200 QQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPG 259
+ G++ R A G+ Q + G++ PG PP P G
Sbjct: 1241 PEGKSGKQGEKG---RTGAKGAKGY----------QGQLGEMGVPGDPGPPG--TPGPKG 1285
Query: 260 HHGIARHPHQEDG--GIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSG 317
G + P G G Q E G A DG G IV G
Sbjct: 1286 SRG-SLGPTGAPGRMGAQGEPGLAG-YDGHKG----------------------IVGPLG 1321
Query: 318 SWVSPTESCQHVPEEAGEGFPQSALE-ALAGHHVDDGVDAAVDVGKGDTQGVQLIQQ--- 373
E + + EG P + G D G D G +GVQ ++
Sbjct: 1322 PPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG--DPGYPGQEGVQGLRGKPG 1379
Query: 374 QEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVM 433
Q+G PG GP P G K GA+G + + G Q G P VV
Sbjct: 1380 QQGQPGHPGPRGWPGPKGSK------GAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVV- 1432
Query: 434 LYNGRE-------QDGQRQAGEEVGYRQVEEPDGIDGPLG 466
GR+ DG + G + + DG GP+G
Sbjct: 1433 ---GRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMG 1469
Score = 35.4 bits (80), Expect = 0.15
Identities = 112/458 (24%), Positives = 148/458 (32%), Gaps = 109/458 (23%)
Query: 26 EHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPA 85
EHG + EG ++G P GP GVRG P+ G +K G
Sbjct: 1214 EHGEKG--QEGLMGEDG--PPGPPGVTGVRG------PEGKSGKQGEK-----GRTGAKG 1258
Query: 86 ASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVD 145
A G Q G + G GP P GS LG GA PG +P +
Sbjct: 1259 AKGYQGQLGEMGVP-GDPGPP-GTPGPKGSRGSLGPTGA--------PGRMGAQGEPGLA 1308
Query: 146 GGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGG 205
G GH PL PPG P+ ++ E G + E G G + G
Sbjct: 1309 GYD-------------GHKGIVGPLG--PPG-PKGEKGEQGEDGKAEGPPGPPGDRGPVG 1352
Query: 206 QRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIAR 265
R G+ + + + GQ QPG HP P G G A
Sbjct: 1353 DRGDR-------GEPGDPGYPGQEGVQGLRGKPGQQGQPG--HPGPRGWPGPKGSKG-AE 1402
Query: 266 HPHQEDG--GIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPT 323
P + G G RG Q + G G V R E P
Sbjct: 1403 GPKGKQGKAGAPGRRG-VQGLQGLPGPRGVVGRQGLEGIAGP------------------ 1443
Query: 324 ESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGP 383
+P G+ Q G DDG D G G + G+PG AG
Sbjct: 1444 ---DGLPGRDGQAGQQ-------GEQGDDG-----DPGPMGPAG------KRGNPGVAGL 1482
Query: 384 SEVLAPDGFKHQQKAVGADG-----GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGR 438
P GFK + G G G E G+ Q E G + G P +
Sbjct: 1483 PGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPG--SKGQPGDSGEMGFPGMA 1540
Query: 439 EQDGQRQAGEEVGYRQVEEP---------DGIDGPLGL 467
G + ++G++ ++ P +GI GPLG+
Sbjct: 1541 GLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGI 1578
Score = 33.5 bits (75), Expect = 0.56
Identities = 108/443 (24%), Positives = 146/443 (32%), Gaps = 90/443 (20%)
Query: 53 GVRGRHSEHQPQQVVGCPA-DKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKK 111
G G + P G P + +P G RP G + G G GP +
Sbjct: 940 GQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDP----GRPGPVGEQ-- 993
Query: 112 PDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG--GGHGEQQGQCPGCPTGHLHPARP 169
G +G G + + G ++ P V G G G PG P G P P
Sbjct: 994 --GFMGFIGLVGEPGI--VGEKGDRGMMGPPGVPGPKGSMGH-----PGMPGGMGTPGEP 1044
Query: 170 LNRRPPGR--PESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQD 227
+ PPG P G + D G G+Q G + RP +
Sbjct: 1045 GPQGPPGSRGPPGMRGAKGRRGPRGPD-GPAGEQGSRGLKGPPGPQGRPG--------RP 1095
Query: 228 GQRQTAQQIRH----GQVEQPGGTHPPAGH-LPSHPGHHGIARHPHQEDGGIQWERGHAQ 282
GQ+ A + H G PG + PP LP PG G Q G E G
Sbjct: 1096 GQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQG-----PQGPIGPPGEMGPK- 1149
Query: 283 RVDGQAGAIQAVHRAVREVAVIPILVADRIVPHS-GSWVSPTESC----QHVPEEAGEGF 337
G GA+ P L + + G +P E + P G+
Sbjct: 1150 ---GPPGAVGE-----------PGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSG 1195
Query: 338 PQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQK 397
P + L G D G D G+ +G + + ++G PG G + V P+G +Q
Sbjct: 1196 PMGP-DGLKGDRGDPGPD-----GEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQG 1249
Query: 398 ------AVGADGGQEQDAGVHVEQDEG--------GQDAAGGPAKGPVVMLYNGREQDGQ 443
A GA G Q Q + V D G G + GP P G+
Sbjct: 1250 EKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAP-----------GR 1298
Query: 444 RQAGEEVGYRQVEEPDGIDGPLG 466
A E G + GI GPLG
Sbjct: 1299 MGAQGEPGLAGYDGHKGIVGPLG 1321
Score = 30.4 bits (67), Expect = 4.8
Identities = 33/126 (26%), Positives = 47/126 (37%), Gaps = 11/126 (8%)
Query: 359 DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDA--------G 410
D+G G + ++ + G G GP L P+G + GA G + Q G
Sbjct: 914 DIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPG 973
Query: 411 VHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECR 470
+ + E G GP M + G G+ E G R + P G+ GP G
Sbjct: 974 LDGVKGEPGDPGRPGPVGEQGFMGFIGLV--GEPGIVGEKGDRGMMGPPGVPGPKG-SMG 1030
Query: 471 HPDHQG 476
HP G
Sbjct: 1031 HPGMPG 1036
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/201 (26%), Positives = 73/201 (36%), Gaps = 37/201 (18%)
Query: 7 GSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQV 66
G + + RG++ R E G G + + G QGP G RG P +
Sbjct: 950 GPQGIAGQRGVVGLPGQRGERGFPGL--PGPSGEPG--KQGPSGASGERGPPGPMGPPGL 1005
Query: 67 VGCPADKKPHHNGCAQRPAASGCPAQEGTVAA--GHGHQGPQEAKKKPDGSHRILGAGGA 124
G P + +G P A G P ++G+ A G GP P GA GA
Sbjct: 1006 AGPPGE-----SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP-------GAPGA 1053
Query: 125 AVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAE 184
PG V PA G GE P G P P+ R P P+ +
Sbjct: 1054 --------PG----PVGPAGKSGDRGETG------PAGPAGPVGPVGARGPAGPQGPRGD 1095
Query: 185 VGTESCQEQDAGIHGQQDDGG 205
G E+ ++ D GI G + G
Sbjct: 1096 KG-ETGEQGDRGIKGHRGFSG 1115
Score = 42.4 bits (98), Expect = 0.001
Identities = 110/443 (24%), Positives = 137/443 (30%), Gaps = 62/443 (13%)
Query: 45 PQGPGQECGVRGRHSEHQPQQVVGCPADK-KPHHNGCAQRPAASGCPAQEGTVAAGHGHQ 103
P GP G G G P + P G A+G P +G G
Sbjct: 693 PAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD----RGDA 748
Query: 104 GPQEAKKKP--DGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPT 161
GP+ A P DG + G G PG PA G GE P PT
Sbjct: 749 GPKGADGSPGKDGVRGLTGPIGP--------PG-------PAGAPGDKGESGPSGPAGPT 793
Query: 162 GHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTG 221
G P +R PG P G Q G G+ D G + A P G
Sbjct: 794 GAR--GAPGDRGEPG-PPGPAGFAGPPGADGQP-GAKGEPGDAGAKGDAGPP-GPAGPAG 848
Query: 222 NGHCQDGQRQTAQQIRHGQVEQPGGT-HPPAGHLPSHPGHHGIARHPH------QEDG-G 273
+ G PG T P A PG G A P +E G G
Sbjct: 849 PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908
Query: 274 IQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEA 333
+ E G A R G+ G A + + A ++ +P +
Sbjct: 909 PRGETGPAGR-PGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQR 967
Query: 334 GE-GFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGF 392
GE GFP L G + G QG + G PG GP + P G
Sbjct: 968 GERGFP-----GLPGPSGEPG-----------KQGPSGASGERGPPGPMGPPGLAGPPGE 1011
Query: 393 KHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGP-------AKGPV--VMLYNGREQDGQ 443
++ A GA+G +D + D G AG P A GPV R + G
Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGP 1071
Query: 444 RQAGEEVGYRQVEEPDGIDGPLG 466
VG P G GP G
Sbjct: 1072 AGPAGPVGPVGARGPAGPQGPRG 1094
Score = 41.6 bits (96), Expect = 0.002
Identities = 109/455 (23%), Positives = 147/455 (32%), Gaps = 45/455 (9%)
Query: 31 AAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCP----ADKKPHHNGCAQRPAA 86
A ++G+A +G P+G GVRG P G AD +P G P
Sbjct: 348 AVGAKGEAGPQG--PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405
Query: 87 SGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDG 146
+G P G G QGP P G+ GA G+ V + P
Sbjct: 406 AGAPGFPGARGPS-GPQGPG-GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463
Query: 147 GGHGEQQGQCPGCPTGHLHPARPLNRRPPGR-----------PESQEAEVGTESCQEQDA 195
G G++ + PTG P P R PG P+ E G+ A
Sbjct: 464 GEEGKRGARGEPGPTGL--PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG----PA 517
Query: 196 GIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGH-- 253
G G + G RP TG+ +T GQ +PG PP
Sbjct: 518 GPKGSPGEAG-RPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQ 576
Query: 254 --LPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADR 311
+ PG G A P G ERG V G GA+ + A P A
Sbjct: 577 AGVMGFPGPKGAAGEP-----GKAGERG----VPGPPGAVGPAGKDGEAGAQGPPGPAGP 627
Query: 312 IVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLI 371
+ + Q +P AG P V + A G +G
Sbjct: 628 AGERGEQGPAGSPGFQGLPGPAG---PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE 684
Query: 372 QQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPV 431
+ +G PG AGP G + GA G ++ G + AAG P GP
Sbjct: 685 RGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLP--GPK 742
Query: 432 VMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLG 466
+ + G++ G R + P G GP G
Sbjct: 743 GDRGDAGPKGADGSPGKD-GVRGLTGPIGPPGPAG 776
Score = 33.5 bits (75), Expect = 0.56
Identities = 39/138 (28%), Positives = 55/138 (39%), Gaps = 16/138 (11%)
Query: 332 EAGEGFPQSA-LEALAGHHVDDGVDAAV-DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAP 389
+ G P +A L + GH G+D A D G +G + G PG+ G + P
Sbjct: 250 QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKG------EPGSPGENGAPGQMGP 303
Query: 390 DGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPA-KGPVVMLYNGREQDGQRQAGE 448
G ++ GA G AG ++G AAG P GP + +AG
Sbjct: 304 RGLPGERGRPGAPG----PAG--ARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGP 357
Query: 449 EVGYRQVEEPDGIDGPLG 466
+ G R E P G+ G G
Sbjct: 358 Q-GPRGSEGPQGVRGEPG 374
Score = 32.0 bits (71), Expect = 1.6
Identities = 33/115 (28%), Positives = 39/115 (33%), Gaps = 9/115 (7%)
Query: 361 GKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG--------GQEQDAGVH 412
G+ G + +G G AGP P G AVGA G G E GV
Sbjct: 311 GRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR 370
Query: 413 VEQDEGGQDAAGGPAKGPVVMLYNG-REQDGQRQAGEEVGYRQVEEPDGIDGPLG 466
E G A GPA P G + +G G+ P G GP G
Sbjct: 371 GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG 425
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 42.0 bits (97), Expect = 0.002
Identities = 77/358 (21%), Positives = 106/358 (29%), Gaps = 38/358 (10%)
Query: 177 RPESQEAEVGTESCQEQDAG---------IHGQQDDGGQRPTAHCTIRPVASTGNGHCQD 227
RP+SQE G Q ++G HGQ D T H ST G
Sbjct: 1439 RPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGD----TTRHAHYHHGKSTQRGSSTT 1494
Query: 228 GQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWER---GHAQRV 284
G+R + GG+H +GH HG + H E I +R H Q
Sbjct: 1495 GRRGSGHSESSDSEVHSGGSHTHSGHT------HGQSGSQHGESESIIHDRHRITHGQTG 1548
Query: 285 D-------GQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGF 337
D G Q R D V HSG P S +H +AG
Sbjct: 1549 DTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEV-HSGGSHRP-HSREHTYGQAGSQH 1606
Query: 338 PQSALEALAGHHVDDGV------DAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDG 391
+ H G + G+ +G + +Q ++ SEV +
Sbjct: 1607 EEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVS 1666
Query: 392 FKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEE-V 450
H G G Q + V + G G + Q G R G
Sbjct: 1667 HTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTGSRTTGRRGS 1726
Query: 451 GYRQVEEPDGIDGPLGLECRHPDHQGIAQHSHQEDDCKDDQGQDVWNTQRVRSFIHRG 508
G+ + + +G G H Q +QH E + G T H G
Sbjct: 1727 GHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSG 1784
Score = 40.8 bits (94), Expect = 0.004
Identities = 66/275 (24%), Positives = 91/275 (33%), Gaps = 70/275 (25%)
Query: 23 GREEHGIEAAV--SEGKAHDEGFSPQGPGQECGVR--GR----HSEHQPQQVVGCPADKK 74
G HG + + G G S G + G R GR HSE +V ++
Sbjct: 2137 GSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEV---HSEAS 2193
Query: 75 PHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPG 134
P H+G A S Q G+ +GHG QG + H H+
Sbjct: 2194 PTHSGHTHSQAGSR-HGQSGS--SGHGRQGTTHGQTGDTTRH----------AHY----- 2235
Query: 135 WEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQD 194
G G Q+G +R RR G ES ++EV +
Sbjct: 2236 -----------GYGQSTQRG------------SRTTGRRGSGHSESSDSEVHSWGSHTHS 2272
Query: 195 AGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHG-----QVEQPGGTHP 249
I GQ ++P ST +G + QT RHG Q Q G
Sbjct: 2273 GHIQGQAGSQQRQP---------GSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSS 2323
Query: 250 PAGHLPSHPG---HHGIAR-HPHQEDGGIQWERGH 280
A H SH HG ++ H G +++ GH
Sbjct: 2324 RASHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGH 2358
Score = 40.4 bits (93), Expect = 0.005
Identities = 85/387 (21%), Positives = 119/387 (30%), Gaps = 51/387 (13%)
Query: 149 HGEQQGQCPGCPTGHLHP---------ARPLNRRPPGRPESQEAEVGTESCQEQDAGIHG 199
HG GQ G T H H +R RR G E ++E + Q + H
Sbjct: 1767 HGTIHGQT-GDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHT 1825
Query: 200 QQDDGGQRPTA-------HCTIRPVASTGNGHCQDGQRQTAQ-------QIRHGQVEQP- 244
G Q + H T +GH Q G Q+ Q + R G E
Sbjct: 1826 HGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSD 1885
Query: 245 -----GGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWER---GHAQRVD----GQAGAIQ 292
GG+H +GH H AR H E +R H Q D G Q
Sbjct: 1886 SEVHSGGSHTHSGHT------HSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQ 1939
Query: 293 AVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDD 352
+ R ++ S VS T S H +AG +P+S H
Sbjct: 1940 TIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHS-GHTHGQAGSHYPESGSSVHERHGTTH 1998
Query: 353 GVDAAV------DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQE 406
G A G+ +G + ++ + SE + H A G G Q
Sbjct: 1999 GQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQH 2058
Query: 407 QDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEE-VGYRQVEEPDGIDGPL 465
++G V + G G + Q G R AG G+ + + + G
Sbjct: 2059 GESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVS 2118
Query: 466 GLECRHPDHQGIAQHSHQEDDCKDDQG 492
H Q +QH QG
Sbjct: 2119 HTHSGHTYGQARSQHGESGSAIHGRQG 2145
Score = 31.2 bits (69), Expect = 2.8
Identities = 58/252 (23%), Positives = 81/252 (32%), Gaps = 42/252 (16%)
Query: 21 SFGREEHG---IEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHH 77
S G++ HG +E K+H G E G E + + C + H
Sbjct: 191 SGGKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHE 250
Query: 78 NGCAQ-----RPAASGCPAQEGTVAAGH--------GHQGPQEAKKKPDGSHRILGAGGA 124
+ Q + S C + H G PQ A SHR G G
Sbjct: 251 SNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASSSCQ-SHRFGGQGNQ 309
Query: 125 AVVHHTLQPGWEVLLVQPAVDGG-GHG-EQQGQCPGC------PTGHLHPARPLNRRPPG 176
+Q G Q + GG GHG GQ GC P + R R G
Sbjct: 310 ---FSYIQSG-----CQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENG 361
Query: 177 RPESQEAEVGTESCQEQDAGIHG----QQDDGGQRPTAHCTIRPVASTGNGHCQ-----D 227
+P++ + T S Q G +G Q GQ C +S+ N +
Sbjct: 362 QPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGS 421
Query: 228 GQRQTAQQIRHG 239
G Q+ +HG
Sbjct: 422 GSSQSTSFEQHG 433
Score = 30.0 bits (66), Expect = 6.2
Identities = 51/237 (21%), Positives = 80/237 (33%), Gaps = 24/237 (10%)
Query: 23 GREEHGIEAAVS-------EGKAHDEGFSPQGPG--QECGVRGRHSEHQPQQVVGCPADK 73
G +HG+ + S G GF G G Q G G+H Q G +
Sbjct: 566 GFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGF-GQHESRSGQSSYGQHSSG 624
Query: 74 KPHHNGCAQ----RPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAG-GAAVVH 128
+G Q + + G + + G G G + G H + G+G +
Sbjct: 625 SSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQH-VSGSGQSSGFGQ 683
Query: 129 HTLQPGWEV-----LLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEA 183
H + G + G HG GQ G L + + G Q +
Sbjct: 684 HESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSS 743
Query: 184 EVGTE-SCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHG 239
G S Q +G + GQ +++ +S +G+ Q G RQT+ +HG
Sbjct: 744 GFGQHGSGSGQSSGFGQHESRSGQ--SSYGQHSSGSSQSSGYGQHGSRQTSGFGQHG 798
>gi|239757829 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 35/195 (17%)
Query: 61 HQPQQVVGCPADKKPHHN-----GCAQRPAASGCP--AQEGTVAAGHGHQGPQEAKKKPD 113
HQ QV+G PA+ K HH+ Q P A G Q+ +A GH QG Q+A
Sbjct: 21 HQHHQVIGGPAEGKGHHDHHHQPHGPQAPLAPGNQQHGQDVGIAVGHDQQGQQKA----- 75
Query: 114 GSHRILGAGGAAVVHHTLQPGWEVLLVQPAV----------DGGGHGEQQGQCPGCPTGH 163
SH++ A H WEV+L V D GE+Q + P G
Sbjct: 76 -SHQLQHPQSRAA--HL----WEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGE 128
Query: 164 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAS--TG 221
H R G + V ++ Q++ + + ++G T H G
Sbjct: 129 GHAGRGPPAVELGGMNYVQVAVKADAGQQEGSCVEVDVEEG----TCHFAEARAKDPLDG 184
Query: 222 NGHCQDGQRQTAQQI 236
+ HC + Q Q Q++
Sbjct: 185 SVHCPERQCQHQQRV 199
Score = 36.6 bits (83), Expect = 0.066
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 353 GVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEV------LAPDGFKHQQKAVGADGGQE 406
GV+A V VG+ + + + +Q E QAG + G + Q AV AD GQ+
Sbjct: 98 GVEALVVVGRQEDEVWEGEKQAEPPDSQAGEGHAGRGPPAVELGGMNYVQVAVKADAGQQ 157
Query: 407 QDAGVHVEQDEGGQDAAGGPAKGPV 431
+ + V V+ +EG A AK P+
Sbjct: 158 EGSCVEVDVEEGTCHFAEARAKDPL 182
>gi|239752340 PREDICTED: hypothetical protein XP_002348205 [Homo
sapiens]
Length = 218
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 35/195 (17%)
Query: 61 HQPQQVVGCPADKKPHHN-----GCAQRPAASGCP--AQEGTVAAGHGHQGPQEAKKKPD 113
HQ QV+G PA+ K HH+ Q P A G Q+ +A GH QG Q+A
Sbjct: 37 HQHHQVIGGPAEGKGHHDHHHQPHGPQAPLAPGNQQHGQDVGIAVGHDQQGQQKA----- 91
Query: 114 GSHRILGAGGAAVVHHTLQPGWEVLLVQPAV----------DGGGHGEQQGQCPGCPTGH 163
SH++ A H WEV+L V D GE+Q + P G
Sbjct: 92 -SHQLQHPQSRAA--HL----WEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGE 144
Query: 164 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAS--TG 221
H R G + V ++ Q++ + + ++G T H G
Sbjct: 145 GHAGRGPPAVELGGMNYVQVAVKADAGQQEGSCVEVDVEEG----TCHFAEARAKDPLDG 200
Query: 222 NGHCQDGQRQTAQQI 236
+ HC + Q Q Q++
Sbjct: 201 SVHCPERQCQHQQRV 215
Score = 36.6 bits (83), Expect = 0.066
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 353 GVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEV------LAPDGFKHQQKAVGADGGQE 406
GV+A V VG+ + + + +Q E QAG + G + Q AV AD GQ+
Sbjct: 114 GVEALVVVGRQEDEVWEGEKQAEPPDSQAGEGHAGRGPPAVELGGMNYVQVAVKADAGQQ 173
Query: 407 QDAGVHVEQDEGGQDAAGGPAKGPV 431
+ + V V+ +EG A AK P+
Sbjct: 174 EGSCVEVDVEEGTCHFAEARAKDPL 198
>gi|239746853 PREDICTED: hypothetical protein XP_002343864 [Homo
sapiens]
Length = 218
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/195 (26%), Positives = 75/195 (38%), Gaps = 35/195 (17%)
Query: 61 HQPQQVVGCPADKKPHHN-----GCAQRPAASGCP--AQEGTVAAGHGHQGPQEAKKKPD 113
HQ QV+G PA+ K HH+ Q P A G Q+ +A GH QG Q+A
Sbjct: 37 HQHHQVIGGPAEGKGHHDHHHQPHGPQAPLAPGNQQHGQDVGIAVGHDQQGQQKA----- 91
Query: 114 GSHRILGAGGAAVVHHTLQPGWEVLLVQPAV----------DGGGHGEQQGQCPGCPTGH 163
SH++ A H WEV+L V D GE+Q + P G
Sbjct: 92 -SHQLQHPQSRAA--HL----WEVVLAVGGVEALVVVGRQEDEVWEGEKQAEPPDSQAGE 144
Query: 164 LHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVAS--TG 221
H R G + V ++ Q++ + + ++G T H G
Sbjct: 145 GHAGRGPPAVELGGMNYVQVAVKADAGQQEGSCVEVDVEEG----TCHFAEARAKDPLDG 200
Query: 222 NGHCQDGQRQTAQQI 236
+ HC + Q Q Q++
Sbjct: 201 SVHCPERQCQHQQRV 215
Score = 36.6 bits (83), Expect = 0.066
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 353 GVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEV------LAPDGFKHQQKAVGADGGQE 406
GV+A V VG+ + + + +Q E QAG + G + Q AV AD GQ+
Sbjct: 114 GVEALVVVGRQEDEVWEGEKQAEPPDSQAGEGHAGRGPPAVELGGMNYVQVAVKADAGQQ 173
Query: 407 QDAGVHVEQDEGGQDAAGGPAKGPV 431
+ + V V+ +EG A AK P+
Sbjct: 174 EGSCVEVDVEEGTCHFAEARAKDPL 198
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 41.2 bits (95), Expect = 0.003
Identities = 54/240 (22%), Positives = 72/240 (30%), Gaps = 36/240 (15%)
Query: 34 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 93
S G H E S Q G G G S H G + C Q A SG +
Sbjct: 581 SSGLGHQESRSGQSSGY--GQHGSSSGHSSTH--GQHGSTSGQSSSCGQHGATSGQSSSH 636
Query: 94 GTVAAG------HGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVL-----LVQP 142
G +G +G QG + G H ++ H GW V
Sbjct: 637 GQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSG 696
Query: 143 AVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQD 202
G GH GQ G + R G Q + + +GQ
Sbjct: 697 QSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG 756
Query: 203 DGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHG 262
G + S+G+G G + ++RHG +GH SH G HG
Sbjct: 757 SGSHQ-----------SSGHGRQGSGSGHSPSRVRHGS---------SSGHSSSH-GQHG 795
Score = 37.0 bits (84), Expect = 0.051
Identities = 60/262 (22%), Positives = 83/262 (31%), Gaps = 41/262 (15%)
Query: 34 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 93
S G H E S Q G G G S H G + C Q A+SG +
Sbjct: 1047 SSGLGHRESRSGQSSGY--GQHGSSSGHSSTH--GQHGSTSGQSSSCGQHGASSGQSSSH 1102
Query: 94 G------TVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 147
G + ++G+G QG + G + H G + G
Sbjct: 1103 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG-------RSSSSG 1155
Query: 148 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 207
HG G+ G GH S ++ G+ S G HG + R
Sbjct: 1156 QHGSGLGESSG--FGH--------HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 1205
Query: 208 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPA--------GHLPSHPG 259
H + +S+ G G RQ++ R G G H P+ GH SH G
Sbjct: 1206 GERHGS-SSGSSSHYGQHGSGSRQSSGHGRQGS----GSGHSPSRGRHGSGLGHSSSH-G 1259
Query: 260 HHGIARHPHQEDGGIQWERGHA 281
HG G + GH+
Sbjct: 1260 QHGSGSGRSSSRGPYESRSGHS 1281
Score = 36.6 bits (83), Expect = 0.066
Identities = 60/262 (22%), Positives = 83/262 (31%), Gaps = 41/262 (15%)
Query: 34 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 93
S G H E S Q G G G S H G + C Q A+SG +
Sbjct: 1987 SSGLGHRESRSGQSSGY--GQHGSSSGHSSTH--GQHGSASGQSSSCGQHGASSGQSSSH 2042
Query: 94 G------TVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 147
G + ++G+G QG + G + H G + G
Sbjct: 2043 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG-------RSSSSG 2095
Query: 148 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 207
HG G+ G GH S ++ G+ S G HG + R
Sbjct: 2096 QHGPGLGESSG--FGH--------HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2145
Query: 208 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPP--------AGHLPSHPG 259
H + +S+ G G RQ++ R G G H P +GH SH G
Sbjct: 2146 GERHGS-SSGSSSRYGQHGSGSRQSSGHGRQGS----GSGHSPSRGRHGSGSGHSSSH-G 2199
Query: 260 HHGIARHPHQEDGGIQWERGHA 281
HG G + GH+
Sbjct: 2200 QHGSGSGRSSSRGPYESRSGHS 2221
Score = 35.4 bits (80), Expect = 0.15
Identities = 59/258 (22%), Positives = 81/258 (31%), Gaps = 33/258 (12%)
Query: 34 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 93
S G H E S Q G G G S H G + C Q A+SG +
Sbjct: 1517 SSGLGHRESRSGQSSGY--GQHGSSSGHSSTH--GQHGSTSGQSSSCGQHGASSGQSSSH 1572
Query: 94 G------TVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 147
G + ++G+G QG + G + H G + G
Sbjct: 1573 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG-------RSSSSG 1625
Query: 148 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 207
HG G+ G GH S ++ G+ S G HG + R
Sbjct: 1626 QHGSGLGESSG--FGH--------HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 1675
Query: 208 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRH----GQVEQPGGTHPPAGHLPSHPGHHGI 263
H + +S+ G G RQ++ R GQ G GH SH G HG
Sbjct: 1676 GERHGS-SSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH-GQHGS 1733
Query: 264 ARHPHQEDGGIQWERGHA 281
G + GH+
Sbjct: 1734 GSGRSSSRGPYESRSGHS 1751
Score = 35.0 bits (79), Expect = 0.19
Identities = 57/284 (20%), Positives = 85/284 (29%), Gaps = 54/284 (19%)
Query: 20 KSFGREEHGIEAAVS---------EGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCP 70
+S G +HG + S G +SP G G G S P +
Sbjct: 2402 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS-----GWSSSRGPYE----- 2451
Query: 71 ADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHT 130
H +G R + SG ++G+G G G H ++ H
Sbjct: 2452 -SGSGHSSGLGHRESRSG-------QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 2503
Query: 131 LQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQ-EAEVGTES 189
G + G HG Q G R+ G +S + G+ S
Sbjct: 2504 ASSG-------QSSSHGQHGSGSSQSSG-----------YGRQGSGSGQSPGHGQRGSGS 2545
Query: 190 CQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ-------VE 242
Q G HG H + S+G GH + Q++ +HG
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGS-GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2604
Query: 243 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 286
Q G + H G + H Q G + GH ++ G
Sbjct: 2605 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 2648
Score = 35.0 bits (79), Expect = 0.19
Identities = 59/258 (22%), Positives = 81/258 (31%), Gaps = 33/258 (12%)
Query: 34 SEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQE 93
S G H E S Q G G G S H G + C Q A+SG +
Sbjct: 2457 SSGLGHRESRSGQSSGY--GQHGSSSGHSSTH--GQHGSTSGQSSSCGQHGASSGQSSSH 2512
Query: 94 G------TVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 147
G + ++G+G QG + G + H G + G
Sbjct: 2513 GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSG-------RSSSSG 2565
Query: 148 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQR 207
HG G+ G GH S ++ G+ S G HG + R
Sbjct: 2566 QHGSGLGESSG--FGH--------HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2615
Query: 208 PTAHCTIRPVASTGNGHCQDGQRQTAQQIRH----GQVEQPGGTHPPAGHLPSHPGHHGI 263
H + +S+ G G RQ++ R GQ G GH SH G HG
Sbjct: 2616 GERHGS-SSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH-GQHGS 2673
Query: 264 ARHPHQEDGGIQWERGHA 281
G + GH+
Sbjct: 2674 GSGRSSSRGPYESRLGHS 2691
Score = 34.3 bits (77), Expect = 0.33
Identities = 60/288 (20%), Positives = 90/288 (31%), Gaps = 53/288 (18%)
Query: 21 SFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVV--------GCPAD 72
S+G+ G ++ G+ H G S Q P RGRH Q G +
Sbjct: 982 SYGQHGSGSRQSLGHGQ-HGSG-SGQSPSPS---RGRHGSGSGQSSSYGPYRSGSGWSSS 1036
Query: 73 KKP------HHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAV 126
+ P H +G R + SG ++G+G G G H ++
Sbjct: 1037 RGPYESGSGHSSGLGHRESRSG-------QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 1089
Query: 127 VHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQ-EAEV 185
H G + G HG Q G R+ G +S +
Sbjct: 1090 GQHGASSG-------QSSSHGQHGSGSSQSSG-----------YGRQGSGSGQSPGHGQR 1131
Query: 186 GTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQ----- 240
G+ S Q G HG H + S+G GH + Q++ +HG
Sbjct: 1132 GSGSRQSPSYGRHGSGSGRSSSSGQHGS-GLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
Query: 241 --VEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 286
Q G + H G + H Q G + GH ++ G
Sbjct: 1191 SGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 1238
Score = 33.9 bits (76), Expect = 0.43
Identities = 55/256 (21%), Positives = 75/256 (29%), Gaps = 48/256 (18%)
Query: 39 HDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA 98
H G G C H E Q G + G +Q +ASG + +G +
Sbjct: 787 HSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGS 846
Query: 99 GHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPG 158
G G G +A H A G HG GQ PG
Sbjct: 847 TSGQSSSSGQHDSSSGQSSSYGQHESASHH--------------ASGRGRHGSGSGQSPG 892
Query: 159 CPTGHLHPARPLNRRPPGRPESQE-AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPV 217
+R G +S G+ S + +G HG GQ
Sbjct: 893 -----------HGQRGSGSGQSPSYGRHGSGSGRSSSSGRHG--SGSGQ----------- 928
Query: 218 ASTGNGHCQDGQRQTAQQIRHG-------QVEQPGGTHPPAGHLPSHPGHHGIARHPHQE 270
S+G GH + Q++ +HG EQ G + H G + Q
Sbjct: 929 -SSGFGH-KSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQH 986
Query: 271 DGGIQWERGHAQRVDG 286
G + GH Q G
Sbjct: 987 GSGSRQSLGHGQHGSG 1002
Score = 32.3 bits (72), Expect = 1.3
Identities = 56/277 (20%), Positives = 85/277 (30%), Gaps = 40/277 (14%)
Query: 20 KSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNG 79
+S G +HG + S + S G G G S + G H +G
Sbjct: 1932 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSR--GPYESGSGHSSG 1989
Query: 80 CAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLL 139
R + SG ++G+G G G H ++ H G
Sbjct: 1990 LGHRESRSG-------QSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSG----- 2037
Query: 140 VQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQ-EAEVGTESCQEQDAGIH 198
+ G HG Q G R+ G +S + G+ S Q G H
Sbjct: 2038 --QSSSHGQHGSGSSQSSG-----------YGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084
Query: 199 GQQDDGGQRPTAHCTIRP--VASTGNGHCQDGQRQTAQQIRHGQ-------VEQPGGTHP 249
G G R ++ P S+G GH + Q++ +HG Q G
Sbjct: 2085 G---SGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG 2141
Query: 250 PAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDG 286
+ H G + Q G + GH ++ G
Sbjct: 2142 QSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178
Score = 32.0 bits (71), Expect = 1.6
Identities = 57/280 (20%), Positives = 90/280 (32%), Gaps = 53/280 (18%)
Query: 20 KSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNG 79
+S G +HG G + +G GQ S + G H +G
Sbjct: 357 QSSGYSKHGS----GSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSG 412
Query: 80 CAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLL 139
Q + SG + GHG +G + G H ++ + G+
Sbjct: 413 RGQHSSGSG-------QSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYS--- 462
Query: 140 VQPAVDGGGHGE----------QQGQCPGCPTGH-LHPARPLNRRPPGRPESQEAEVGTE 188
G GH E Q G G +GH H +R R E Q + G+
Sbjct: 463 -----SGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSR---SGQSSRGERQGSSAGSS 514
Query: 189 SCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTH 248
S +GQ G ++ H + G+G GQ + + RH + ++
Sbjct: 515 SS-------YGQHGSGSRQSLGH------SRHGSG---SGQSPSPSRGRHESGSRQSSSY 558
Query: 249 PPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQA 288
P G+ G P++ G GH + GQ+
Sbjct: 559 GPHGYGSGRSSSRG----PYESGSGHSSGLGHQESRSGQS 594
Score = 31.6 bits (70), Expect = 2.1
Identities = 33/144 (22%), Positives = 47/144 (32%), Gaps = 8/144 (5%)
Query: 147 GGHGEQQGQCPGCPT---GHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQDD 203
G HG GQ T G + + S ++ G+ S G HG +
Sbjct: 206 GQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSG 265
Query: 204 GGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGI 263
R H + +S+ H G RQ+ R G + +H G H HG
Sbjct: 266 QSSRGERHRSSSGSSSSYGQH-GSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHG- 323
Query: 264 ARHPHQEDGGIQWERGHAQRVDGQ 287
H + RGH + GQ
Sbjct: 324 ---QHGSGSSYSYSRGHYESGSGQ 344
Score = 31.2 bits (69), Expect = 2.8
Identities = 57/284 (20%), Positives = 84/284 (29%), Gaps = 54/284 (19%)
Query: 20 KSFGREEHGIEAAVS---------EGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCP 70
+S G +HG + S G +SP G G G S P +
Sbjct: 1462 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS-----GWSSSRGPYE----- 1511
Query: 71 ADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAVVHHT 130
H +G R + SG ++G+G G G H ++ H
Sbjct: 1512 -SGSSHSSGLGHRESRSG-------QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 1563
Query: 131 LQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQ-EAEVGTES 189
G + G HG Q G R+ G +S + G+ S
Sbjct: 1564 ASSG-------QSSSHGQHGSGSSQSSG-----------YGRQGSGSGQSPGHGQRGSGS 1605
Query: 190 CQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPG---G 246
Q G HG H + S+G GH + Q++ +HG G
Sbjct: 1606 RQSPSYGRHGSGSGRSSSSGQHGS-GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 1664
Query: 247 THPPAGHLPSHPGHHGIARHPH----QEDGGIQWERGHAQRVDG 286
H S HG + Q G + GH ++ G
Sbjct: 1665 QHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 40.8 bits (94), Expect = 0.004
Identities = 108/434 (24%), Positives = 135/434 (31%), Gaps = 75/434 (17%)
Query: 47 GPGQECGVRGRHSEHQPQQVVGCPADK-KPHHNGCAQRPAASGCPAQEGTVAAGHGHQGP 105
G E G RG E + G P K + +G P A+G P G A G +GP
Sbjct: 438 GAKGEPGPRGERGE---AGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAP-GFRGP 493
Query: 106 Q-----EAKKKPDGSHRILGAGG----AAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQC 156
+K P G G G A PG + P GG + +
Sbjct: 494 AGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK--- 550
Query: 157 PGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDA--GIHGQQDD-GGQRPTAHCT 213
PG P RP P G P Q +G + D G +G++ GG P
Sbjct: 551 PGPPGSQGESGRPGPPGPSG-PRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG--- 606
Query: 214 IRPVASTGNGHCQDGQRQTAQQIRHGQVEQPG--------GTHPPAGH--LPSHPGHHGI 263
P G Q T G PG GT P G P PG G
Sbjct: 607 --PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD 664
Query: 264 ARHPH----QEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIV--PHSG 317
A P + D G ERG G AGA +R A P + P
Sbjct: 665 AGAPGAPGGKGDAGAPGERGPP----GLAGA-----PGLRGGAGPPGPEGGKGAAGPPGP 715
Query: 318 SWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAV------------------- 358
+ T Q +P E G G + G G D
Sbjct: 716 PGAAGTPGLQGMPGERG-GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774
Query: 359 ---DVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQ 415
D G+G G+ I G PG+ G + P GF G GG + + G E+
Sbjct: 775 QPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGG-KGERGAPGEK 833
Query: 416 DEGGQDAAGGPAKG 429
EGG GP G
Sbjct: 834 GEGGPPGVAGPPGG 847
Score = 40.0 bits (92), Expect = 0.006
Identities = 87/351 (24%), Positives = 117/351 (33%), Gaps = 46/351 (13%)
Query: 91 AQEGTVAAGHGHQGPQEAKK---KPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG 147
AQ+ V G H G A + KP+ + G+ + + E+ P +
Sbjct: 23 AQQEAVEGGCSHLGQSYADRDVWKPEPCQICVCDSGSVLCDDIICDDQELDCPNPEIP-- 80
Query: 148 GHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQ-DDGGQ 206
GE CP PT P RP N + P P+ G + D GI GQ G
Sbjct: 81 -FGECCAVCPQPPT---APTRPPNGQGPQGPKGDPGPPGIPG-RNGDPGIPGQPGSPGSP 135
Query: 207 RPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIARH 266
P C P D + G PG PAG P PG G + H
Sbjct: 136 GPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPG----PAGP-PGPPGPPGTSGH 190
Query: 267 PHQEDG----GIQWERGHA--QRVDGQAGAIQAVHRAVRE-VAVIPILVADRIVPHSGSW 319
P G E G A G GAI A ++ + P +R +P
Sbjct: 191 PGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGI 250
Query: 320 VSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPG 379
P +P GFP + GH DG + KG+T G ++ + G PG
Sbjct: 251 KGPA----GIP-----GFP-----GMKGHRGFDGRNGE----KGET-GAPGLKGENGLPG 291
Query: 380 QAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGP 430
+ G + P G ++ G G AG G D GP P
Sbjct: 292 ENGAPGPMGPRGAPGERGRPGLPGA----AGARGNDGARGSDGQPGPPGPP 338
Score = 34.7 bits (78), Expect = 0.25
Identities = 113/469 (24%), Positives = 149/469 (31%), Gaps = 105/469 (22%)
Query: 44 SPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCAQRPAASGCPAQEGTVAA----- 98
SP GPG + G+ Q G P P +G +P G P +G A
Sbjct: 541 SPGGPGSD----GKPGPPGSQGESGRPGPPGP--SGPRGQPGVMGFPGPKGNDGAPGKNG 594
Query: 99 ------GHGHQGP--QEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGG-GH 149
G G QGP + + P G G GG T PG + L P G G
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDK--GDTGPPGPQGLQGLPGTGGPPGE 652
Query: 150 GEQQGQ--------CPGCPTGHLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQ 201
+ G+ PG P G P R PPG + G AG G
Sbjct: 653 NGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG--------AGPPG-- 702
Query: 202 DDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL--PSHPG 259
+GG+ A T G+R G + PG P G P PG
Sbjct: 703 PEGGKGAAGPPGPPGAAGTPGLQGMPGER--------GGLGSPG----PKGDKGEPGGPG 750
Query: 260 HHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSW 319
G+ G RG + A Q + +P + R P
Sbjct: 751 ADGVP--------GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802
Query: 320 VSPTESCQHVPEEAGEGFPQSALEALAGHHVDDG----VDAAVDVGKGDTQGVQLIQQQE 375
P P A GFP G + + G A + G+G GV
Sbjct: 803 TGP-------PGPA--GFP-----GAPGQNGEPGGKGERGAPGEKGEGGPPGV------A 842
Query: 376 GDPGQAGPSEVLAPDGFKHQQKAVGADG--------------GQEQDAGVHVEQDEGGQD 421
G PG +GP+ P G K ++ + G G G + G G+D
Sbjct: 843 GPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD 902
Query: 422 AAGGPA---KGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGL 467
GPA P +G + D Q GE+ G + P G GPLG+
Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDA-GQPGEK-GSPGAQGPPGAPGPLGI 949
Score = 33.5 bits (75), Expect = 0.56
Identities = 31/106 (29%), Positives = 40/106 (37%), Gaps = 12/106 (11%)
Query: 376 GDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLY 435
G PG AGP P G + G+ G Q E GQ GP P +
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG-------EPGQAGPSGPPGPPGAIGP 223
Query: 436 NGRE-QDGQRQAGEEVGYRQVEEPDGIDGPLGLECRHPDHQGIAQH 480
+G +DG+ G R + P GI GP G+ P G+ H
Sbjct: 224 SGPAGKDGESGRPGRPGERGLPGPPGIKGPAGI----PGFPGMKGH 265
Score = 32.0 bits (71), Expect = 1.6
Identities = 64/262 (24%), Positives = 80/262 (30%), Gaps = 47/262 (17%)
Query: 45 PQGPGQECGVRGRHSEHQPQQVVGCPADK-KPHHNGCAQRPAASGCPAQEGT-------- 95
P GP G G P+ G P +K P G P G G
Sbjct: 904 PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPG 963
Query: 96 VAAGHGHQGPQEAK--------------KKPDGSHRILG-AGGAAVVHHTLQPGWEVLLV 140
+ G GPQ K + P G + G AG A PG + L
Sbjct: 964 MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGL-- 1021
Query: 141 QPAVDG--GGHGEQ-QGQCPGCPTGHLHPARPLNRRPPGR-----------PESQEAEVG 186
P DG GG G++ + PG P HP P P G+ P G
Sbjct: 1022 -PGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080
Query: 187 TESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGG 246
+ G G + + G+R A GN QQ G + PG
Sbjct: 1081 SRGAPGPQ-GPRGDKGETGERGAAGIKGHR-GFPGNPGAPGSPGPAGQQ---GAIGSPGP 1135
Query: 247 THPPAGHLPS-HPGHHGIARHP 267
P PS PG G + HP
Sbjct: 1136 AGPRGPVGPSGPPGKDGTSGHP 1157
Score = 31.6 bits (70), Expect = 2.1
Identities = 30/96 (31%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 372 QQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAGVHVEQDEGGQDAAGGPAKGPV 431
Q G+PGQAGPS P G G D G+ G E+ G GPA P
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKD-GESGRPGRPGERGLPGPPGIKGPAGIPG 258
Query: 432 VMLYNG-REQDGQRQAGEEVGYRQVEEPDGIDGPLG 466
G R DG+ E G ++ +G+ G G
Sbjct: 259 FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG 294
>gi|239744358 PREDICTED: hypothetical protein XP_002343105 [Homo
sapiens]
Length = 767
Score = 40.4 bits (93), Expect = 0.005
Identities = 50/179 (27%), Positives = 67/179 (37%), Gaps = 19/179 (10%)
Query: 25 EEHGIEA--AVSEGKAHDEG-FSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCA 81
EEHG++ +V E DEG G + C G + ++ G + GC
Sbjct: 49 EEHGVKGVESVLEKGVLDEGVLEAWGCCRRCRHAGWNRSQPSPELAGAVIHARAPAVGCR 108
Query: 82 QRPAASGC---------PAQEGTVAAGHGHQGP-QEAKKKPDGSHRIL--GAGGAAVVHH 129
QR P QE P E +KP+GS + G G AV
Sbjct: 109 QRSGHLHVRLKQRLLERPCQEPLGKKYQLELPPLYERARKPEGSKNLPADGQGLRAVRAD 168
Query: 130 TLQPGWEVLLVQP---AVDGGGHGEQQGQCPGCPTGHLH-PARPLNRRPPGRPESQEAE 184
P W +P A + G G+ QGQ P T HL P P +PE++EAE
Sbjct: 169 AALPVWPGGPGRPGPHAPEAGAEGQHQGQWPPADTRHLRTPKWPYKVATEEKPEAEEAE 227
>gi|14249622 ajuba isoform 1 [Homo sapiens]
Length = 538
Score = 40.0 bits (92), Expect = 0.006
Identities = 45/138 (32%), Positives = 57/138 (41%), Gaps = 19/138 (13%)
Query: 81 AQRPAASGC--------PA--QEGTVA-AGHGHQGPQEAKKKPDGSHRILGAGGAAVVHH 129
AQRPA GC PA G +A AG G GP E + G H + G G A V
Sbjct: 216 AQRPAGFGCQESRHSYPPALGSPGALAGAGVGAAGPLERRGAQPGRHSVTGYGDCA-VGA 274
Query: 130 TLQPGWEVLLVQPAVDGGGHGEQQGQCPGC-PTGHLHPARPL----NRRPPGRPESQEAE 184
Q LL GG +G+ G P+G P P R PE++E
Sbjct: 275 RYQDELTALLRLTVGTGGREAGARGEPSGIEPSGLEEPPGPFVPEAARARMREPEAREDY 334
Query: 185 VGTESCQEQDAGIHGQQD 202
GT C + + GI+GQ +
Sbjct: 335 FGT--CIKCNKGIYGQSN 350
>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
Length = 689
Score = 40.0 bits (92), Expect = 0.006
Identities = 113/450 (25%), Positives = 147/450 (32%), Gaps = 102/450 (22%)
Query: 45 PQGPGQECGVRGRHSEHQPQQVVGCPADK-KPHHNGCAQRPAASG---CPAQEGTVAAGH 100
P G E G+RG + P G P KP G Q S CP
Sbjct: 126 PVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTN-----CPP 180
Query: 101 GHQGPQ--EAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPG 158
G +GP + K G ILG G H +PG P D G GEQ P
Sbjct: 181 GMKGPPGLQGVKGHAGKRGILGDPG-----HQGKPG-------PKGDVGASGEQGIPGPP 228
Query: 159 CPTG---HLHPARPLNRRPPGRPESQEAEVGTESCQEQD--------AGIHGQQDDGGQR 207
P G + A P P + +G ++ AG G + G R
Sbjct: 229 GPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIR 288
Query: 208 PTAHCTIRPVASTG----NGHCQDGQRQT-AQQIRHGQVEQPGGTHPPAGHLPSHPGHHG 262
T P +TG NG +DG T + GQ QPG P H G G
Sbjct: 289 GPQGIT-GPKGATGPPGING--KDGTPGTPGMKGSAGQAGQPGS--------PGHQGLAG 337
Query: 263 IARHPHQEDG-GIQWERGHAQRVDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVS 321
+ P + G G Q E G Q + G +G
Sbjct: 338 VPGQPGTKGGPGDQGEPG-PQGLPGFSGP------------------------------- 365
Query: 322 PTESCQHVPEEAGEGFPQSAL--EALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPG 379
P + GE P+ + + + G D G V G+ QG Q + ++G PG
Sbjct: 366 --------PGKEGEPGPRGEIGPQGIMGQKGDQGERGPV--GQPGPQGRQGPKGEQGPPG 415
Query: 380 QAGPSEVLAPDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNG 437
GP + G K G G G AG+ E+ E G+ GP KG
Sbjct: 416 IPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP-KGQ----QGV 470
Query: 438 REQDGQRQAGEEVGYRQVEEPDGIDGPLGL 467
R + G + G V+ G GP GL
Sbjct: 471 RGEPGYPGPSGDAGAPGVQGYPGPPGPRGL 500
Score = 31.6 bits (70), Expect = 2.1
Identities = 70/281 (24%), Positives = 89/281 (31%), Gaps = 67/281 (23%)
Query: 45 PQGPGQECGVRGRHSEHQPQQVVGCPADK----KPHHNGCAQRPAASGCPAQEGTVAAGH 100
PQG G +G PQ + G DK K G P +G P ++G
Sbjct: 401 PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGES- 459
Query: 101 GHQGPQEAKKKPDGSHRILGAGGAAVVHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCP 160
G GP+ G + G G PG P+ D G G Q P P
Sbjct: 460 GEPGPK-------GQQGVRGEPG--------YPG-------PSGDAGAPGVQGYPGPPGP 497
Query: 161 TGHLHPARPLNRRPPGRPESQEAE-----------VGTESCQEQDA-------------- 195
G NR PG+P Q E V + QEQ A
Sbjct: 498 RGLAG-----NRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAV 552
Query: 196 GIHGQQDDGG-------QRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTH 248
G+ G G Q P H R V Q G T + + G+ PG
Sbjct: 553 GMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGN--TGPKGKRGEKGDPGEVG 610
Query: 249 PPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAG 289
+P PG G+ P Q G +RG + G+AG
Sbjct: 611 RGHPGMPGPPGIPGLPGRPGQAINGKDGDRG-SPGAPGEAG 650
>gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens]
Length = 610
Score = 39.7 bits (91), Expect = 0.008
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 58/303 (19%)
Query: 174 PPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTA 233
PPG+P Q G G++ G+ P C A+ + + + +
Sbjct: 168 PPGQPGPQ--------------GQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQS 213
Query: 234 QQIRHGQVEQPGGTHP--PAGH--LPSHPGHHGIARHPHQE-DGGIQWERGHAQR----- 283
Q G PG P P GH LP G G+ P + D GIQ G
Sbjct: 214 QASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPG 273
Query: 284 VDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALE 343
+ G+ GA A AV + P + + E+ EG P L
Sbjct: 274 MPGKHGAKGAPGIAVAGMKGEPGIPGTK------------------GEKGAEGSP--GLP 313
Query: 344 ALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG 403
L G + G DA +G G + + G PG GP G Q G G
Sbjct: 314 GLLGQKGEKG-DAGNSIGGG--------RGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPG 364
Query: 404 GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDG 463
+ + + +G + + G P KG +V YNG +A +E+ + P G+ G
Sbjct: 365 DKGERGAAGEQGPDGPKGSKGEPGKGEMVD-YNG----NINEALQEIRTLALMGPPGLPG 419
Query: 464 PLG 466
+G
Sbjct: 420 QIG 422
>gi|22027605 alpha 1 type XIII collagen isoform 17 [Homo sapiens]
Length = 657
Score = 39.7 bits (91), Expect = 0.008
Identities = 72/303 (23%), Positives = 106/303 (34%), Gaps = 58/303 (19%)
Query: 174 PPGRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTA 233
PPG+P Q G G++ G+ P C A+ + + + +
Sbjct: 159 PPGQPGPQ--------------GQKGEKGQCGEYPHRECLSSMPAALRSSQIIALKGEQS 204
Query: 234 QQIRHGQVEQPGGTHP--PAGH--LPSHPGHHGIARHPHQE-DGGIQWERGHAQR----- 283
Q G PG P P GH LP G G+ P + D GIQ G
Sbjct: 205 QASIQGPPGPPGPPGPSGPLGHPGLPGPMGPPGLPGPPGPKGDPGIQGYHGRKGERGMPG 264
Query: 284 VDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALE 343
+ G+ GA A AV + P + + E+ EG P L
Sbjct: 265 MPGKHGAKGAPGIAVAGMKGEPGIPGTK------------------GEKGAEGSP--GLP 304
Query: 344 ALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADG 403
L G + G DA +G G + + G PG GP G Q G G
Sbjct: 305 GLLGQKGEKG-DAGNSIGGG--------RGEPGPPGLPGPPGPKGEAGVDGQVGPPGQPG 355
Query: 404 GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDG 463
+ + + +G + + G P KG +V YNG +A +E+ + P G+ G
Sbjct: 356 DKGERGAAGEQGPDGPKGSKGEPGKGEMVD-YNG----NINEALQEIRTLALMGPPGLPG 410
Query: 464 PLG 466
+G
Sbjct: 411 QIG 413
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 39.7 bits (91), Expect = 0.008
Identities = 38/140 (27%), Positives = 48/140 (34%), Gaps = 26/140 (18%)
Query: 146 GGGHGEQQGQCPGCPTG---HLHPARPLNRRPPGRPESQEAEVGTESCQEQDAGIHGQQD 202
GG + P P G H HP +P PP P+ ++ HG
Sbjct: 266 GGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHS-------------HGPPL 312
Query: 203 DGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL-PSHP-GH 260
G P + P++ + CQ T RH HP H HP GH
Sbjct: 313 PQGPPP-----LLPMSCSS---CQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGH 364
Query: 261 HGIARHPHQEDGGIQWERGH 280
H A HPH+ D Q GH
Sbjct: 365 HPHAHHPHEHDTHRQHPHGH 384
>gi|239755481 PREDICTED: similar to Putative uncharacterized protein
ENSP00000334305 [Homo sapiens]
Length = 771
Score = 39.3 bits (90), Expect = 0.010
Identities = 50/183 (27%), Positives = 66/183 (36%), Gaps = 23/183 (12%)
Query: 25 EEHGIEA--AVSEGKAHDEG-FSPQGPGQECGVRGRHSEHQPQQVVGCPADKKPHHNGCA 81
EEHG++ +V E DEG G + C G + ++ G + GC
Sbjct: 49 EEHGVKGVESVLEKGVLDEGVLEAWGCCRRCRHAGWNRSQPSPELAGAVVHARAPAVGCR 108
Query: 82 QRPAASGC---------PAQEGTVAAGHGHQGP-QEAKKKPDGSHRIL--GAGGAAVVHH 129
QR P QE P E +KP+GS + G G AV
Sbjct: 109 QRSGHLHVRLKQRLLERPCQEPLGKKYQLELPPLYERARKPEGSKNLPADGQGLRAVRAD 168
Query: 130 TLQPGWE-------VLLVQPAVDGGGHGEQQGQCPGCPTGHLH-PARPLNRRPPGRPESQ 181
P W PA + G G+ QGQ P T HL P P +PE++
Sbjct: 169 AALPVWPGGPGRPGSRAHLPAPEAGAEGQHQGQWPPADTRHLRTPKWPYKVVTEEKPEAE 228
Query: 182 EAE 184
EAE
Sbjct: 229 EAE 231
>gi|239749957 PREDICTED: hypothetical protein [Homo sapiens]
Length = 707
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Query: 16 GILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQVVGCPADKKP 75
G L S GR+ H + + V +G+A + G++G+H+ H P G P P
Sbjct: 175 GKCLGSAGRQRHVVHSGVGQGQAQ----------AKAGLQGQHAVHLPGWPQGVPLGNGP 224
Query: 76 HHNGCAQRPAASGCPAQEGT-VAAGHGHQGPQEAKKKPDGSHRI 118
G P G P GT V +G ++A PD H++
Sbjct: 225 PGVGQHVCPVLQGLPRGPGTQVHLAYGLSSERQA-AVPDSQHQV 267
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 39.3 bits (90), Expect = 0.010
Identities = 69/329 (20%), Positives = 126/329 (38%), Gaps = 37/329 (11%)
Query: 174 PPGRPES--QEAEVGTESCQEQDAGIHGQQDDG-GQRPTAHCTIRPVASTGNGHCQDGQR 230
P GR + +E G E Q+++ G++D G G+ + +A +DG+
Sbjct: 651 PEGRGDGTCEEGSSGAEHWQDEERE-KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEE 709
Query: 231 QTAQQIRHGQVEQPGGTHPPAGHLPSHPGHHGIA-RHPHQEDGGIQWERGHAQRVDGQA- 288
Q ++ G ++ G G R +E G E G + V+G+
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGERE 769
Query: 289 ---GAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEAL 345
G + RA +E + TE EE GE
Sbjct: 770 KEEGERKKEERAGKEEK------GEEEGDQGEGEEEETEGRGEEKEEGGE---------- 813
Query: 346 AGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLAPDGFKHQQKAVGADGGQ 405
V+ G V+ GKG+ + + ++ EG+ + G E +G + + + G + G+
Sbjct: 814 ----VEGG---EVEEGKGEREEEE--EEGEGEE-EEGEGEEEEGEGEEEEGEGKGEEEGE 863
Query: 406 EQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPL 465
E + E+ EG + G +G G E++G+ + GEE G + EE +G +G
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE-GEEEGEGEGEEEEG-EGKG 921
Query: 466 GLECRHPDHQGIAQHSHQEDDCKDDQGQD 494
E + +G + E + + +G++
Sbjct: 922 EEEGEEGEGEGEEEEGEGEGEDGEGEGEE 950
Score = 34.7 bits (78), Expect = 0.25
Identities = 62/323 (19%), Positives = 121/323 (37%), Gaps = 31/323 (9%)
Query: 176 GRPESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQ 235
G+ E + EV E +E++ G +++ G+ G G+ + +
Sbjct: 755 GKEEGEGEEVEGE--REKEEGERKKEERAGKE-----------EKGEEEGDQGEGEEEET 801
Query: 236 IRHGQVEQPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAGAIQAVH 295
G+ ++ GG G + G R +E+G + E G + +G+ +
Sbjct: 802 EGRGEEKEEGG-EVEGGEVEEGKGE----REEEEEEGEGEEEEGEGEEEEGEGEEEEGEG 856
Query: 296 RAVREVAVIPILVADRIVPHSGSWVSPTESCQHVPEEAGEGFPQSALEALAGHHVDDGVD 355
+ E G E + EE GEG + G +G
Sbjct: 857 KGEEEGEE----GEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEG 912
Query: 356 AAVD-VGKGDTQGVQLI---QQQEGD-PGQAGPSEVLAPDGFKHQQKAVGADGGQEQDAG 410
+ GKG+ +G + +++EG+ G+ G E +G ++ G G+E+ G
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972
Query: 411 VHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQAGEEVGYRQVEEPDGIDGPLGLECR 470
E+ EG + G +G G E+ + GEE G + EE + + +E
Sbjct: 973 -EGEEGEGEGEEEEGEGEGEEE---EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGE 1028
Query: 471 HPDHQGIAQHSHQEDDCKDDQGQ 493
+ +G + +E + ++ +G+
Sbjct: 1029 EGEGEGEEEEGEEEGEEREKEGE 1051
Score = 33.1 bits (74), Expect = 0.73
Identities = 56/287 (19%), Positives = 95/287 (33%), Gaps = 56/287 (19%)
Query: 7 GSEKLETTRGILLKSFGREEHGIEAAVSEGKAHDEGFSPQGPGQECGVRGRHSEHQPQQV 66
G E+ RG + G E G V EGK E +G G+E G E + ++
Sbjct: 796 GEEEETEGRGEEKEEGGEVEGG---EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE 852
Query: 67 VGCPADKKPHHNGCAQRPAASGCPAQEGTVAAGHGHQGPQEAKKKPDGSHRILGAGGAAV 126
G G + G +EG G G + E + + +G G G
Sbjct: 853 EG---------EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGE----GEG---- 895
Query: 127 VHHTLQPGWEVLLVQPAVDGGGHGEQQGQCPGCPTGHLHPARPLNRRPPGRPESQ----E 182
+G G GE++G+ G G E + E
Sbjct: 896 ---------------EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940
Query: 183 AEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIRPVASTGNGHCQDGQRQTAQQIRHGQVE 242
E G +E++ G++++G G G ++G+ + ++ G+ E
Sbjct: 941 GEDGEGEGEEEEGEWEGEEEEGEGEG---------EEEGEGEGEEGEGEGEEEEGEGEGE 991
Query: 243 QPGGTHPPAGHLPSHPGHHGIARHPHQEDGGIQWERGHAQRVDGQAG 289
+ G G G +E+G ++ E V+G+ G
Sbjct: 992 EEEGEE--EGEEEGEGEEEGEGEGEEEEEGEVEGE------VEGEEG 1030
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 39.3 bits (90), Expect = 0.010
Identities = 78/317 (24%), Positives = 110/317 (34%), Gaps = 33/317 (10%)
Query: 157 PGCPTGHLHPARPLNRRPPGRP-ESQEAEVGTESCQEQDAGIHGQQDDGGQRPTAHCTIR 215
PG P H +P R P G P +Q+ E G + GI G + D G+R C +
Sbjct: 250 PGPPGTHGNPGIKGERGPKGNPGNAQKGEAG----ERGPGGIPGYKGDKGER--GECG-K 302
Query: 216 PVASTGNGHCQDGQRQTAQQIRHGQVEQPGGTHPPAGHL-----PSHPGHHGIARHPHQE 270
P G + + I+ + P G P G P PG +G P
Sbjct: 303 PGIKGDKGSPGPYGPKGPRGIQG--ITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG 360
Query: 271 DGGIQWERGHAQR--VDGQAGAIQAVHRAVREVAVIPILVADRIVPHSGSWVSPTESCQH 328
GI+ ERG R G G + R +P +R +P G E
Sbjct: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVP---GERGLPGEGFPGPKGEKGSE 417
Query: 329 VPEEAGEGFPQSALEALAGHHVDDGVDAAVDVGKGDTQGVQLIQQQEGDPGQAGPSEVLA 388
P +G +++ G G + + +QG Q IQ G PG GP A
Sbjct: 418 GPT-GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGP----A 472
Query: 389 PDGFKHQQKAVGADG--GQEQDAGVHVEQDEGGQDAAGGPAKGPVVMLYNGREQDGQRQA 446
G + VG G G G+ V+ +G + G P + V +DG
Sbjct: 473 GQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGV------PGEDGAAGK 526
Query: 447 GEEVGYRQVEEPDGIDG 463
E G P+G G
Sbjct: 527 KGEAGLPGARGPEGPPG 543
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.135 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,375,386
Number of Sequences: 37866
Number of extensions: 1808553
Number of successful extensions: 5697
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 229
Number of HSP's that attempted gapping in prelim test: 4566
Number of HSP's gapped (non-prelim): 1194
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.