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Search of human proteins with 117938310
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117938310 sine oculis binding protein homolog [Homo sapiens]
(873 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117938310 sine oculis binding protein homolog [Homo sapiens] 1832 0.0
gi|193788649 retinoic acid induced 2 [Homo sapiens] 128 2e-29
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 101 3e-21
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 101 3e-21
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 92 3e-18
gi|116284392 mucin 2 precursor [Homo sapiens] 87 5e-17
gi|160707881 formin 2 [Homo sapiens] 84 7e-16
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 82 2e-15
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 82 2e-15
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 82 2e-15
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 82 2e-15
gi|163965366 nascent polypeptide-associated complex alpha subuni... 82 2e-15
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 82 3e-15
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 81 4e-15
gi|150417989 cyclin K isoform 1 [Homo sapiens] 79 1e-14
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 79 2e-14
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 79 2e-14
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 78 3e-14
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 78 3e-14
gi|23510333 pygopus homolog 2 [Homo sapiens] 78 4e-14
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 76 1e-13
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 76 2e-13
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 75 3e-13
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 74 5e-13
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 74 6e-13
gi|47132519 Ras association and pleckstrin homology domains 1 is... 74 6e-13
gi|146134388 YLP motif containing 1 [Homo sapiens] 74 8e-13
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 73 1e-12
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 73 1e-12
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 73 1e-12
>gi|117938310 sine oculis binding protein homolog [Homo sapiens]
Length = 873
Score = 1832 bits (4746), Expect = 0.0
Identities = 873/873 (100%), Positives = 873/873 (100%)
Query: 1 MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIE 60
MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIE
Sbjct: 1 MAEMEKEGRPPENKRSRKPAHPVKREINEEMKNFAENTMNELLGWYGYDKVELKDGEDIE 60
Query: 61 FRSYPTDGESRQHISVLKENSLPKPKLPEDSVISPYNISTGYSGLATGNGLSDSPAGSKD 120
FRSYPTDGESRQHISVLKENSLPKPKLPEDSVISPYNISTGYSGLATGNGLSDSPAGSKD
Sbjct: 61 FRSYPTDGESRQHISVLKENSLPKPKLPEDSVISPYNISTGYSGLATGNGLSDSPAGSKD 120
Query: 121 HGSVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFA 180
HGSVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFA
Sbjct: 121 HGSVPIIVPLIPPPFIKPPAEDDVSNVQIMCAWCQKVGIKRYSLSMGSEVKSFCSEKCFA 180
Query: 181 ACRRAYFKRNKARDEDGHAENFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDF 240
ACRRAYFKRNKARDEDGHAENFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDF
Sbjct: 181 ACRRAYFKRNKARDEDGHAENFPQQHYAKETPRLAFKNNCELLVCDWCKHIRHTKEYLDF 240
Query: 241 GDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSW 300
GDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSW
Sbjct: 241 GDGERRLQFCSAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSW 300
Query: 301 NIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPN 360
NIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPN
Sbjct: 301 NIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPN 360
Query: 361 IPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHAS 420
IPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHAS
Sbjct: 361 IPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHAS 420
Query: 421 NPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPP 480
NPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPP
Sbjct: 421 NPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPP 480
Query: 481 PGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIP 540
PGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIP
Sbjct: 481 PGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIP 540
Query: 541 IPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPG 600
IPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPG
Sbjct: 541 IPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPG 600
Query: 601 CSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGH 660
CSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGH
Sbjct: 601 CSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGH 660
Query: 661 RARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAAC 720
RARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAAC
Sbjct: 661 RARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAAC 720
Query: 721 NVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNC 780
NVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNC
Sbjct: 721 NVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNC 780
Query: 781 HLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAM 840
HLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAM
Sbjct: 781 HLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAM 840
Query: 841 APCIISSPMLSAGPEDLEPPLKRRCLRIRNQNK 873
APCIISSPMLSAGPEDLEPPLKRRCLRIRNQNK
Sbjct: 841 APCIISSPMLSAGPEDLEPPLKRRCLRIRNQNK 873
>gi|193788649 retinoic acid induced 2 [Homo sapiens]
Length = 530
Score = 128 bits (322), Expect = 2e-29
Identities = 93/285 (32%), Positives = 128/285 (44%), Gaps = 50/285 (17%)
Query: 285 NKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTK 344
N+ E QL+T ++WNI TD +KA V P+ S P+++ + K
Sbjct: 23 NRLENGMAQLITTEAWNINSTDLVKKALVTV----------PAPSILNPPAESQSGMALK 72
Query: 345 IPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIM 404
+ V + + + E+P + P+ +Q S P L P + VMT +GPV LP+ +EQ +
Sbjct: 73 VAATVLQPLCLGESPVVMPIHMQVEGSSAPELN-PNGNATYVMTTQGPVQLPVVLEQHVF 131
Query: 405 QQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPS 464
Q + P + P A +S + N + G P P+ L + PS
Sbjct: 132 QHLNSPLVL--PQEAPCSSSTIHNNLFQGAEDPEAQPQLLD--------------LRIPS 175
Query: 465 TPTMPGNP-----PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVP 519
P P P L P P P P P + +P P P L+PLVP
Sbjct: 176 QPQEPTLPFEAVLQNLFPSQGTLGPPPCQPPPGYAPVPPQPFSSP---------LSPLVP 226
Query: 520 PPTLLVPYPVIVPLPVPIPIPIPIPHVSDS---------KPPNGF 555
P TLLVPYPVIVPLPVP+PIPIPIP S KPP+ F
Sbjct: 227 PATLLVPYPVIVPLPVPVPIPIPIPMPQSSESKFSSSFPKPPSSF 271
Score = 33.1 bits (74), Expect = 1.2
Identities = 28/105 (26%), Positives = 40/105 (38%), Gaps = 14/105 (13%)
Query: 326 PSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPM 385
PS T P +P P P S P+S P +PP ++ P + PL VP
Sbjct: 193 PSQGTLGPPPCQPPPGYAPVP-PQPFSSPLS--PLVPPATLLVPYPVIVPLPVPV----- 244
Query: 386 VMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM 430
P+P+PI M Q + F + P +P P+
Sbjct: 245 ------PIPIPIPMPQSSESKFSSSFPKPPSSFGLHPFKGTQTPL 283
Score = 33.1 bits (74), Expect = 1.2
Identities = 14/26 (53%), Positives = 15/26 (57%)
Query: 740 PPPEQPPPPPPPAPPKKLLSPEEPAV 765
PPP QPPP P PP+ SP P V
Sbjct: 200 PPPCQPPPGYAPVPPQPFSSPLSPLV 225
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 101 bits (252), Expect = 3e-21
Identities = 109/401 (27%), Positives = 145/401 (36%), Gaps = 49/401 (12%)
Query: 268 QANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPS 327
Q+ P L +T H + QL TP +PL AP + T PS
Sbjct: 314 QSQAPPTLPATPH------SSSLTCQLATP----LPLAPPSPSAPPSLQTLPSPPATPPS 363
Query: 328 ASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVM 387
+TT S T + + +P+P P+S PP + PPA PPL PP P
Sbjct: 364 QATTSLGSPTLQATHSFLPSP-----PLSPLATPPPQA--PPALALPPLQAPPSPPASPP 416
Query: 388 TNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSP-LSNPMLPGIGPPPGGPRNLG- 445
+ P P + ++ PF P P SP S P+ P PP P +L
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
Query: 446 -----PTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGP 500
P S P PM PP P PP L PPP AP P+L PP+ +P+ P
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPP 535
Query: 501 MPVPQMMNFGLPSLAPLVP--------PPTLLVPYPVIVPLPVPIPI-------PIPIPH 545
P F + P+ P PP L P + P P P P P P
Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595
Query: 546 VSDSKPPNGFS-SNGENFIPNAPGDSAAAGGKPSGHSLSP-------RDSKQGSSKSADS 597
S S P + + G P+ S +G +GHS S R G A +
Sbjct: 596 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655
Query: 598 PPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSP-PGPPGAG 637
P + + P G + + G+P P PP G
Sbjct: 656 SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 696
Score = 73.6 bits (179), Expect = 8e-13
Identities = 99/396 (25%), Positives = 143/396 (36%), Gaps = 65/396 (16%)
Query: 312 PSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPAS 371
PSP A S P S + +P A S+ P VP S P S PP+S P++
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-----PPMS---PSA 495
Query: 372 IGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPML 431
PP PP + P + + P P + +Q + P P +P++ L PM
Sbjct: 496 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMS 553
Query: 432 PGIGPPPGGPRNLG-PTSSPMHRPMLSPHIHPPSTPTMPG-----NPPGLL-------PP 478
P PPP P L P P SP + P P PG + P L PP
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613
Query: 479 PPPGAPLPSLPFPPVSMMPNGPMPVPQMM---NFGLPSLAPLVPPPTLLV---------- 525
PP +P +L P ++ + P+ + + G A PPP +
Sbjct: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673
Query: 526 -PYPVIVPLPVPIPIPIPIPHVSDSKPPNG----FSSNGENFIPNAPG------------ 568
P P + P P+P P + +G + + G APG
Sbjct: 674 GPAPPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 732
Query: 569 DSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAG 628
AAAG S SP+ ++ G + P G +L + +H S + L G
Sbjct: 733 GKAAAGAGAGASSRSPKQARLG-----ELPLG------ALQASVVQHLLSRTLLLAAAEG 781
Query: 629 SPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARL 664
+ G G G GV G + + D +G A L
Sbjct: 782 AAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAEL 817
Score = 63.2 bits (152), Expect = 1e-09
Identities = 119/504 (23%), Positives = 164/504 (32%), Gaps = 137/504 (27%)
Query: 278 TLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDT 337
T P M ++ G ++ P P AR + P+ +GP S S+ S T
Sbjct: 171 TPSPAMARRSRAAGTEVGLPR----PAPSARPRPPT--------EGPRKSVSSASEHSTT 218
Query: 338 ANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVM-TNRGPVPLP 396
P+P + P + P S + +S PL P RS P T R P P
Sbjct: 219 E-------PSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARSGPSARGTPRAPAH-P 269
Query: 397 IFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPML 456
+ + +Q +RPP + P A+ PLS SSP+ P
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGPLS--------------------SSPLATPSP 309
Query: 457 SPHIHPPSTPTMPGNP-----------PGLLPPPPPGAP--LPSLPFPPVSMMPNGPM-- 501
S + + PT+P P P L PP P AP L +LP PP +
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
Query: 502 --PVPQMMNFGLPS--LAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSS 557
P Q + LPS L+PL PP P + PL P P P P +S P+ +
Sbjct: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP-PSPPASPPLSPLATPSPQAP 428
Query: 558 NG-------ENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAP 610
N F P A P+ +SP ++ + +PP + L + P
Sbjct: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-----SATPPSQAPPSLAAPPLQVPP 483
Query: 611 TPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHR 670
+P SPP P A P L P
Sbjct: 484 SPP--------------ASPPMSPSATPPPQAPPPLAAPP-------------------- 509
Query: 671 ALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGA 730
++ + P A PPA P A P A+
Sbjct: 510 -----LQLAKPPPQA--------------PPALATPPLQALPSPPASFP----------G 540
Query: 731 AAEGAKSAEPPPEQPPPPPPPAPP 754
A + SA P PPP APP
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPP 564
Score = 51.2 bits (121), Expect = 4e-06
Identities = 115/478 (24%), Positives = 156/478 (32%), Gaps = 86/478 (17%)
Query: 349 VPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLP------------ 396
+P+S P + S + PAS P G R+PP T+ GPV P
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 397 ------IFMEQQIMQ------QIRPPFIRGPPHHASNPNSPLSNPMLP----------GI 434
I E+ + + R G S P +P + G+
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 435 GPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPT-----MPGNPPGLLPP-----PPPGAP 484
P R PT P + + S H + P+ P GL P P
Sbjct: 190 PRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 485 L--PSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPL-PVPIPIPI 541
L P+ P P P Q GL +L P P P + PL P+ P
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 542 PIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLS-PRDSKQGSSKSADSPPG 600
P + PP +P P S+ + L+ P S S ++ SPP
Sbjct: 309 PSAALQSQAPPT---------LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359
Query: 601 C-SGQALSLAPTP---AEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDL 656
QA + +P A H L+ A PP P A L P LQ P
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA---LALP-PLQAPPSPPASP 415
Query: 657 TVGHRARLHNVIHRALHAH-VKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGA---PA 712
+ A AL H ++A P + SPPA+ P A
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP------VQAPFSPPASPPVSPSATPPSQ 469
Query: 713 GPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPP----------PPPPAPPKKLLSP 760
P + AA + V + A+ + SA PPP+ PPP PPP APP P
Sbjct: 470 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527
Score = 42.0 bits (97), Expect = 0.002
Identities = 74/322 (22%), Positives = 100/322 (31%), Gaps = 71/322 (22%)
Query: 467 TMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVP 526
T PGLL P PPG+P P P P ++ G G PL +
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAA--------GAVGRKPLAERAGGI-- 65
Query: 527 YPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRD 586
IP P ++ G SS P A G A P + SP
Sbjct: 66 --------GGATIPESAPRAGPTRSA-GTSSRNPASRPPASGRGERA---PPAKNTSPGP 113
Query: 587 SKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRR-----------AGSPPGPP- 634
S + PG GQ R + + +R +G PG P
Sbjct: 114 VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173
Query: 635 --------GAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAE 686
AG ++G P P T G R + + H E P+A
Sbjct: 174 PAMARRSRAAGTEVGLP--RPAPSARPRPPTEGPRKSVSSA-----SEHSTTEPSPAARR 226
Query: 687 RRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTR-GAAAEGAKSAEPPPEQP 745
R + GG G PA +++ + + R G +A G A P QP
Sbjct: 227 RPSAGG--------------GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP 272
Query: 746 PP-------PPPPAPPKKLLSP 760
P PP PP+K +P
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAP 294
Score = 34.3 bits (77), Expect = 0.52
Identities = 78/349 (22%), Positives = 111/349 (31%), Gaps = 54/349 (15%)
Query: 510 GLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGD 569
G + P P LL P P P P P P + + + + G + G
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAA------GAVGRKPLAERAGG 64
Query: 570 SAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGS 629
A S P S SS++ S P SG+ AP PA++ V RA
Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG-ERAP-PAKNTSPGPVSSPGRASG 122
Query: 630 PPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRT 689
P G LG G+ R + R SA RR
Sbjct: 123 TTRP----GPLGQKGL---------------RISAEETVARGKATEAPKRSALSAGARRD 163
Query: 690 CGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPP 749
G P G P P + +R A E P P P PP
Sbjct: 164 TSG--------PTPGTPSPA-------------MARRSRAAGTE-VGLPRPAPSARPRPP 201
Query: 750 PPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEA-LAGGDKSDPNLNN 808
P K + S E + +E ++ L A++ L L+ +S P+
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 809 PADEDHAYALRMLPKTGCVIQP--VPKPAEKAAMA-PCIISSPMLSAGP 854
A+ + PK ++P V P + AA A + SSP+ + P
Sbjct: 262 -TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 101 bits (251), Expect = 3e-21
Identities = 104/388 (26%), Positives = 140/388 (36%), Gaps = 39/388 (10%)
Query: 281 PPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANC 340
PP ++ A G +P + P AP + T PS +TT S T
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337
Query: 341 SVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFME 400
+ + +P+P P+S PP + PPA PPL PP P + P P
Sbjct: 338 THSFLPSP-----PLSPLATPPPQA--PPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390
Query: 401 QQIMQQIRPPFIRGPPHHASNPNSP-LSNPMLPGIGPPPGGPRNLG------PTSSPMHR 453
+ ++ PF P P SP S P+ P PP P +L P S P
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 450
Query: 454 PMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPS 513
PM PP P PP L PPP AP P+L PP+ +P+ P P F +
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 514 LAPLVP--------PPTLLVPYPVIVPLPVPIPI-------PIPIPHVSDSKPPNGFS-S 557
P+ P PP L P + P P P P P P S S P + +
Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 569
Query: 558 NGENFIPNAPGDSAAAGGKPSGHSLSP-------RDSKQGSSKSADSPPGCSGQALSLAP 610
G P+ S +G +GHS S R G A + P + + P
Sbjct: 570 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 629
Query: 611 TPAEHGRSEVVDLTRRAGSP-PGPPGAG 637
G + + G+P P PP G
Sbjct: 630 AAWSRGPAPPLAFRGAPGAPLPWPPATG 657
Score = 73.6 bits (179), Expect = 8e-13
Identities = 99/396 (25%), Positives = 143/396 (36%), Gaps = 65/396 (16%)
Query: 312 PSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPAS 371
PSP A S P S + +P A S+ P VP S P S PP+S P++
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS-----PPMS---PSA 456
Query: 372 IGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPML 431
PP PP + P + + P P + +Q + P P +P++ L PM
Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMS 514
Query: 432 PGIGPPPGGPRNLG-PTSSPMHRPMLSPHIHPPSTPTMPG-----NPPGLL-------PP 478
P PPP P L P P SP + P P PG + P L PP
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574
Query: 479 PPPGAPLPSLPFPPVSMMPNGPMPVPQMM---NFGLPSLAPLVPPPTLLV---------- 525
PP +P +L P ++ + P+ + + G A PPP +
Sbjct: 575 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 634
Query: 526 -PYPVIVPLPVPIPIPIPIPHVSDSKPPNG----FSSNGENFIPNAPG------------ 568
P P + P P+P P + +G + + G APG
Sbjct: 635 GPAPPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 693
Query: 569 DSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAG 628
AAAG S SP+ ++ G + P G +L + +H S + L G
Sbjct: 694 GKAAAGAGAGASSRSPKQARLG-----ELPLG------ALQASVVQHLLSRTLLLAAAEG 742
Query: 629 SPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARL 664
+ G G G GV G + + D +G A L
Sbjct: 743 AAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAEL 778
Score = 62.0 bits (149), Expect = 2e-09
Identities = 121/518 (23%), Positives = 166/518 (32%), Gaps = 125/518 (24%)
Query: 307 ARRKAPSPVATAGQSQG---PGP--------SASTTVSPSDTANCSVTKIPTPVPKSIPI 355
A+ +P PV++ G++ G PGP SA TV+ + +
Sbjct: 97 AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS 156
Query: 356 SETPNIP-PVSVQPPASIGPPLGVP---PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPF 411
TP P P + + G +G+P P + P T + E + P
Sbjct: 157 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPA 214
Query: 412 IRGPPHHASNPNSP----LSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPH----IHPP 463
R P P LS+ P P GP G +P H P + PP
Sbjct: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274
Query: 464 S-TPTMPGNPPGLLP-------------PPPPGAP--LPSLPFPPVSMMPNGP----MPV 503
TP P L P PP P AP L +LP PP + P
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 504 PQMMNFGLPS--LAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNG-- 559
Q + LPS L+PL PP P + PL P P P P +S P+ + N
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP-PSPPASPPLSPLATPSPQAPNALA 393
Query: 560 -----ENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAE 614
F P A P+ +SP ++ + +PP + L + P+P
Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSP-----SATPPSQAPPSLAAPPLQVPPSP-- 446
Query: 615 HGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHA 674
SPP P A P L P
Sbjct: 447 ------------PASPPMSPSATPPPQAPPPLAAPP------------------------ 470
Query: 675 HVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEG 734
++ + P A SPPA+ PG AP P A+ + +
Sbjct: 471 -LQLAKPPPQAPPALATPPLQALPSPPAS-FPGQ-APFSPSASLPMSPL----------- 516
Query: 735 AKSAEPPPEQPP---------PPPPPAPPKKLLSPEEP 763
A PPP+ PP PP PPA P L +P P
Sbjct: 517 ---ATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRP 550
Score = 43.9 bits (102), Expect = 7e-04
Identities = 81/321 (25%), Positives = 106/321 (33%), Gaps = 39/321 (12%)
Query: 467 TMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPV----PQMMNFG------LPSLAP 516
T PGLL P PPG+P P P P ++ G P G +P AP
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 517 LVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGK 576
P P P P + S P SS G PG G +
Sbjct: 76 RAGPTRTSRP-----PASGRGERAPPAKNTS----PGPVSSPGRASGTTRPGPLGQKGLR 126
Query: 577 PSGHSLSPR----DSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEV----VDLTRRAG 628
S R ++ + S+ SA + SG P+PA RS V L R A
Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTEVGLPRPAP 185
Query: 629 SP-PGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRAR--LHNVIHRALHAHVKAEREPSAA 685
S P PP G + V + + + R R + R + + P ++
Sbjct: 186 SARPRPPTEGPR---KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242
Query: 686 ERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEP--PPE 743
R+ R +P A P P G +A V A A G S+ P P
Sbjct: 243 PARSGPSARG---TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 299
Query: 744 QPPPPPPPAPPKKLLSPEEPA 764
PP P APP P PA
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPA 320
Score = 35.4 bits (80), Expect = 0.23
Identities = 80/359 (22%), Positives = 108/359 (30%), Gaps = 67/359 (18%)
Query: 510 GLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGD 569
G + P P LL P P P P P P + G
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAAL---------------------RVLGA 49
Query: 570 SAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGS 629
+ A G KP L+ R G + +S P S P GR E +
Sbjct: 50 AGAVGRKP----LAERAGGIGGATIPESAPRAGPTRTSRPPAS---GRGE--------RA 94
Query: 630 PPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRT 689
PP + G + PG G G R + R SA RR
Sbjct: 95 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 154
Query: 690 CGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPP 749
G P G P P + +R A E P P P PP
Sbjct: 155 TSG--------PTPGTPSPA-------------MARRSRAAGTE-VGLPRPAPSARPRPP 192
Query: 750 PPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEA-LAGGDKSDPNLNN 808
P K + S E + +E ++ L A++ L L+ +S P+
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252
Query: 809 PADEDHAYALRMLPKTGCVIQP--VPKPAEKAAMAPCIISS-----PMLSAGPEDLEPP 860
A+ + PK ++P V P + AA A +SS P SA P PP
Sbjct: 253 -TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 91.7 bits (226), Expect = 3e-18
Identities = 106/397 (26%), Positives = 139/397 (35%), Gaps = 68/397 (17%)
Query: 303 PLTDARRKAPSPVATAGQS----------QG-PGPSASTTVSPSDTANCSVTKIPTPVPK 351
PLT + PS +AT QG P P S +P A + P P
Sbjct: 575 PLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634
Query: 352 SIPISETPNIPPVSVQPPAS--------IGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQI 403
S P S P + P++ P + + P PP SPP+ P P+
Sbjct: 635 SPPAS--PPLSPLATPSPQAPNALAVHLLQAPFSPPP-SPPVQAPFSPPASPPVSPSATP 691
Query: 404 MQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLG------PTSSPMHRPMLS 457
Q PP + PP P+ P S PM P PPP P L P S P PM
Sbjct: 692 PSQA-PPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749
Query: 458 PHIHPPSTPTMPGNPPGLLPP-------------PPPGAPLPSLPFPPVSMMPNGPMPVP 504
PP P + PP +PP PPP AP P+L PP+ +P+ P P
Sbjct: 750 SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP-PALATPPLQALPSPPASFP 808
Query: 505 QMMNFGLPSLAPLVP--------PPTLLVPYPVIVPLPVPIPI-------PIPIPHVSDS 549
F + P+ P PP L P + P P P P P P S S
Sbjct: 809 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868
Query: 550 KPPNGFS-SNGENFIPNAPGDSAAAGGKPSGHSLSP-------RDSKQGSSKSADSPPGC 601
P + + G P+ S +G +GHS S R G A + P
Sbjct: 869 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928
Query: 602 SGQALSLAPTPAEHGRSEVVDLTRRAGSP-PGPPGAG 637
+ + P G + + G+P P PP G
Sbjct: 929 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 965
Score = 86.7 bits (213), Expect = 9e-17
Identities = 135/538 (25%), Positives = 184/538 (34%), Gaps = 102/538 (18%)
Query: 281 PPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSAST----TVSPSD 336
PP ++ A G PL+ + PSP T + P +A+T T+ PS
Sbjct: 287 PPRKDAAPALG-----------PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335
Query: 337 TANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLP 396
+ P P P + P +T PP + PP+ P + PP P + P+ +P
Sbjct: 336 PLATPLPLAP-PSPSAPPSLQTLPSPPAT--PPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 397 IFMEQQIMQQIRPPFIRGPPHHASNPNSP-------------------LSNPMLPGIGPP 437
+ +Q P ++ SP L++P P P
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA-STP 451
Query: 438 PGGPRNLGPTSSPMHRPM---LSPHIHPPSTPTM--PGNPPGLLPPPPPGAPLPSLPFPP 492
P P P S P P+ LSP + P S+P P L P APL SL PP
Sbjct: 452 PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPP 511
Query: 493 VSMM-----PNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVP----LPVPIPIPIPI 543
+ P+ P + L +L L PPP P+ P P P P P+
Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571
Query: 544 PHVSDSKPPNGFSSNGENFIPNAPGDSAA--AGGKPSGHSLSPRDSKQGSS--------- 592
P + PP S+ P AP A+ G PS LSP + +
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS-PPLSPLATPPPQAPPXLALPPL 630
Query: 593 KSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDG 652
++ SPP + P+P V L PP PP +Q P
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-----------VQAPFSP 679
Query: 653 VIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGA-- 710
V A PS A SPPA+ P A
Sbjct: 680 PASPPVSPSA-----------------TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722
Query: 711 -PAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPP---PPP---PPAPPKKL-LSP 760
P P AA + V + A+ + SA PPP PP PP PP+PP L +SP
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Score = 84.0 bits (206), Expect = 6e-16
Identities = 138/560 (24%), Positives = 188/560 (33%), Gaps = 113/560 (20%)
Query: 281 PPMENKAEGTGVQLLTPDSWNIPLTDARRK----APSPVATAGQSQGPGPSASTTVSPSD 336
P ++ + G+Q L P P DA + SP+AT P + + V P D
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS----PSGTKARPVPPPD 321
Query: 337 TANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASI----GPPLGVPPRSPPMVMTN--R 390
A T +P +P S P++ + P S P S+ PP P ++PP + T +
Sbjct: 322 NA---ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378
Query: 391 GPVPLPIFMEQQIMQQIRPPFIRGPPH---------------------HASNPNSP---- 425
P L Q+ + P ++ PP H+ SP
Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
Query: 426 --LSNPMLPGIGPPPGGPRNLGPTSSPMHRPM---LSPHIHPPSTPTM--PGNPPGLLPP 478
L++P P PP P P S P P+ LSP + P S+P P L
Sbjct: 439 ASLTSPSRPASTPPDSPPLQ-APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497
Query: 479 PPPGAPLPSLPFPPVSMM-----PNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPL 533
P APL SL PP+ P+ P + L +L L PPP P+ P
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557
Query: 534 ----PVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAG--GKPSGHSLSPRDS 587
P P P P+ P + PP S+ P AP A+ G PS LSP +
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP-PLSPLAT 616
Query: 588 KQGSS---------KSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGG 638
+ ++ SPP + P+P V L PP PP
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP---- 672
Query: 639 QLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHC 698
+Q P V A PS A
Sbjct: 673 -------VQAPFSPPASPPVSPSAT-----------------PPSQAPPSLAAPPLQVPP 708
Query: 699 SPPAAGDPGPGA---PAGPEAAAACNVIVNGTRGAAAEGAKSAEPPP-----------EQ 744
SPPA+ P A P P AA + V + A+ + SA PPP +
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768
Query: 745 PPPPPPPAPPKKLLSPEEPA 764
PP PP P L P A
Sbjct: 769 PPSPPASLPMSPLAKPPPQA 788
Score = 67.0 bits (162), Expect = 7e-11
Identities = 103/409 (25%), Positives = 140/409 (34%), Gaps = 101/409 (24%)
Query: 310 KAPSPVATAGQSQGPGPSASTTVSPSDTANCSVT--------KIPTPVPKSIPISETPNI 361
+AP P+A P P AS +SPS T V ++P P S+P+S
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 362 PPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASN 421
PP + PPA PPL P SPP + P AS
Sbjct: 785 PPQA--PPALATPPLQALP-SPPASFPGQAPF----------------------SPSASL 819
Query: 422 PNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPG-----NPPGLL 476
P SPL+ P PP P P P SP + P P PG + P L
Sbjct: 820 PMSPLATP------PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 873
Query: 477 -------PPPPPGAPLPSLPFPPVSMMPNGPMPVPQMM---NFGLPSLAPLVPPPTLLV- 525
PPPP +P +L P ++ + P+ + + G A PPP +
Sbjct: 874 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 933
Query: 526 ----------PYPVI-------VPLPVPIPIPIPIPHVSD-------------SKPPNGF 555
P P + PLP P P P +D + P G
Sbjct: 934 ACHPAAWSRGPAPPLAFRGAPGAPLPWP---PATGPGSADGLCTIYETEGPESATPAPGA 990
Query: 556 SSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEH 615
G + P G AAAG S SP+ ++ G + P G +L + +H
Sbjct: 991 LDPGPS--PGTSGGKAAAGAGAGASSRSPKQARLG-----ELPLG------ALQASVVQH 1037
Query: 616 GRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARL 664
S + L G+ G G G GV G + + D +G A L
Sbjct: 1038 LLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAEL 1086
Score = 58.2 bits (139), Expect = 3e-08
Identities = 126/524 (24%), Positives = 172/524 (32%), Gaps = 98/524 (18%)
Query: 285 NKAEGTGVQLL--TPDSWNIPLTDARRKA-----------PSPVATAGQSQGPG------ 325
++A GT V L P + P T+ RK+ PSP A S G G
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 326 ---PSASTTVSPSDTANCSVTKIPT-------PVPKSIPISETPNIPPVSVQPPASIGPP 375
S++T +S + S P P PK + P + P ++GP
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 376 LGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQI--RPPFIRGPPHHASNPNSPLSNPMLPG 433
P +P T PVP P + + PP P +P++P S LP
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
Query: 434 IGPPPGGPRNLGP---TSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPG----APLP 486
PP P + P T+ PM P I P P +P PP P
Sbjct: 360 ---PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
Query: 487 SLPFPPVSMMPNGPMPVPQMMNFGL--PSLAPLVPPPTLLVPYPVIVPLPVPI-----PI 539
SL P + + P+ L PS PP + + P+ +P P+ P
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476
Query: 540 PIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPP 599
P+ P SS + P AP S + SL+P S Q S +PP
Sbjct: 477 VSPLSSPLTIHPLQALSSLASH-SPQAPLSSLIMPPLETQSSLAP-PSLQTPPASLTTPP 534
Query: 600 GCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVG 659
SLAP P + + + T +PP P P LQ P LT
Sbjct: 535 --LENLPSLAPPPLQTASAPLT--TPHLETPPCPA--------PCPLQAPPS---PLTTP 579
Query: 660 HRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAA 719
++ A + P+ A SPP G P P P P A
Sbjct: 580 PPETPSSI------ATPPPQAPPALA-------------SPPLQGLPSP--PLSPLAT-- 616
Query: 720 CNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEP 763
+ PP Q PP PP +PP L+ P
Sbjct: 617 ----------PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
Score = 55.8 bits (133), Expect = 2e-07
Identities = 117/515 (22%), Positives = 166/515 (32%), Gaps = 80/515 (15%)
Query: 307 ARRKAPSPVATAGQSQG---PGP--------SASTTVSPSDTANCSVTKIPTPVPKSIPI 355
A+ +P PV++ G++ G PGP SA TV+ + +
Sbjct: 106 AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS 165
Query: 356 SETPNIP-PVSVQPPASIGPPLGVP---PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPF 411
TP P P + + G +G+P P + P T + E + P
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPA 223
Query: 412 IRGPPHHASNPNSP----LSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPT 467
R P P LS+ P P GP G +P H PS P
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH----------PSQPK 273
Query: 468 MPG----NPPGLLPP----PPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVP 519
G PP + PP P PL S P S PVP N P A L P
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP 333
Query: 520 PPTLLVPYPVIVPLPVPIP----IPIPIPHVSDSKPPNGFSSNGENFIPNAPG------- 568
P L P P+ P P P +P P P S+ P ++ P+
Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 569 ---DSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTR 625
S + PS +LS S Q ++ + L+++P + + + +R
Sbjct: 393 HSLTSPSLQAPPSPLALS---SLQATTSLGSPTLQATHSFLTMSPRQTQ---ASLTSPSR 446
Query: 626 RAGSPPGPPGAGGQLGFPG--VLQGPQDGVID-----LTVGHRARLHNVIHRALHAHVKA 678
A +PP P L P LQ + LT+ L ++ + A + +
Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506
Query: 679 EREP-----SAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAE 733
P S+ + +PP P P A+A T A
Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP 566
Query: 734 GAKSAEPPPEQPPPP--------PPPAPPKKLLSP 760
A P P PPP PPP P L SP
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601
Score = 38.1 bits (87), Expect = 0.036
Identities = 83/356 (23%), Positives = 120/356 (33%), Gaps = 65/356 (18%)
Query: 467 TMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNG----------------------PMPVP 504
T PGLL P PPG+P P P P ++ G P P
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
Query: 505 QM---MNFGLPSLAPLVPPPTL----LVPYPVIVPLPVPIPIPIPIPHVSDSKP--PNGF 555
+ + G S P PP P P P P+ P + P G
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 556 SSNGENFIPN-----APGDSAAAGGK------PSGHSLSPRDSKQGSSKSADSPPGCSGQ 604
+ E + AP SA + G P+ + SP +++ S++A + G
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR--SRAAGTEVGLPRP 192
Query: 605 ALSLAPTPAEHG-RSEVVDLTRRAGSPPGP-----PGAGGQLGFPGVLQGPQDGVIDLTV 658
A S P P G R V + + + P P P AGG L P + L+
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSS 251
Query: 659 GHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPA-GP-EA 716
R+ + +A PS + + R +PP APA GP +
Sbjct: 252 PARSG------PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD----AAPALGPLSS 301
Query: 717 AAACNVIVNGTRGAAAEGAKSAEPP-PEQPPPPPPPAPPKKLLSPEEPAVSELESV 771
+ +GT+ +A P P PP PP A P L P A L+++
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
Score = 34.7 bits (78), Expect = 0.40
Identities = 83/385 (21%), Positives = 112/385 (29%), Gaps = 83/385 (21%)
Query: 510 GLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGD 569
G + P P LL P P P P P P + + + + G + G
Sbjct: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAA------GAVGRKPLAERAGG 64
Query: 570 SAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGS 629
A S P S SS++ S P SG+ AP PA++ V RA
Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG-ERAP-PAKNTSPGPVSSPGRASG 122
Query: 630 PPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRT 689
P G LG G+ R + R SA RR
Sbjct: 123 TTRP----GPLGQKGL---------------RISAEETVARGKATEAPKRSALSAGARRD 163
Query: 690 CGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPP 749
G P G P P + +R A E P P P PP
Sbjct: 164 TSG--------PTPGTPSPA-------------MARRSRAAGTE-VGLPRPAPSARPRPP 201
Query: 750 PPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEA-LAGGDKSDPNLN- 807
P K + S E + +E ++ L A++ L L+ +S P+
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 808 ------------------------NPADEDHAYALRMLPK--------TGCVIQPVPKPA 835
P +D A AL L +G +PVP P
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 836 EKAAMAPCIISSPMLSAGPEDLEPP 860
A P + A P L PP
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPP 346
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 87.4 bits (215), Expect = 5e-17
Identities = 83/339 (24%), Positives = 117/339 (34%), Gaps = 29/339 (8%)
Query: 303 PLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCS--VTKIPTPVPKSIPI----- 355
P T P+ T + P P +TT +P T S +T TP P + P
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIST 1460
Query: 356 ------SETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRP 409
+ TP+ P + PP + P +PP T P PI + P
Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT-LPP 1519
Query: 410 PFIRGPPHHASNPNSPLSNPMLPGIGP--PPGGPRNLGPTSSPMHRPMLSPHIHPPSTPT 467
PP + P + P P P PP L PT++P P + P +TP+
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1579
Query: 468 MPG----NPPGLLPPPPPGAPLPSLPF-----PPVSMMPNGPMPVPQMMNFGL----PSL 514
P +PP + PP PS P PP + P+ P P P+
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639
Query: 515 APLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAG 574
P PP T P P P P P P + + PP S+ P+ P +
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP 1699
Query: 575 GKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPA 613
+ S + SS + SPP + S TP+
Sbjct: 1700 SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS 1738
Score = 75.5 bits (184), Expect = 2e-13
Identities = 74/294 (25%), Positives = 103/294 (35%), Gaps = 37/294 (12%)
Query: 272 PAGLCSTLHPPMENKAEGTGVQLLTPDSWN-IPLTDARRKAPSPVATAGQSQGPGPSAST 330
P+ +T PP + T P + P T P+ T + P P +T
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529
Query: 331 TVSPSDTANCSV-TKIPTPVPKS---IPISETPNIPPVSVQ--PPASIGPPLGVPPRSPP 384
T +P T S T P P S +P + TP+ PP + PP + P SPP
Sbjct: 1530 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589
Query: 385 MVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGP--PPGGPR 442
+ T P P PP + P + P P P PP
Sbjct: 1590 TITTTTPP----------------PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1633
Query: 443 NLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPM- 501
L PT++P P + P +TP+ PP P P P+ + PP + P+ P+
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPS----PPTTTTPSP---PITTTTTPPPTTTPSSPIT 1686
Query: 502 ----PVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKP 551
P M P+ P P T P P P P + P P + S P
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPP 1740
Score = 61.2 bits (147), Expect = 4e-09
Identities = 63/247 (25%), Positives = 87/247 (35%), Gaps = 20/247 (8%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTANCSVTKIPTP 348
TG Q T P+T P+P T Q+ P + +TTV+P+ T + T TP
Sbjct: 4076 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131
Query: 349 VPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIR 408
+ + ++ TP P Q P + P + P PI +
Sbjct: 4132 ITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4189
Query: 409 PPFIR-GPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPM-----LSPHIH- 461
P + GPP H S +P++ P P+ TSSP+ L P I
Sbjct: 4190 PTGTQTGPPTHTST--APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247
Query: 462 ----PPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPL 517
PPSTPT P G PP + S P P G P + +
Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAW 4307
Query: 518 VPPPTLL 524
P PT L
Sbjct: 4308 TPTPTPL 4314
Score = 59.7 bits (143), Expect = 1e-08
Identities = 64/256 (25%), Positives = 90/256 (35%), Gaps = 65/256 (25%)
Query: 312 PSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPAS 371
PSP T + P P+++TT+ P+ T + T TP P + P PP++ +
Sbjct: 1399 PSPPTT---TPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPS------PPITT---TT 1446
Query: 372 IGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPML 431
PP P SPP+ T P P PP + P+ P + P
Sbjct: 1447 TPPPTTTP--SPPISTTTTPP----------------PTTTPSPP--TTTPSPPTTTP-- 1484
Query: 432 PGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFP 491
PP PT++P P +P P ST T+P P P P + P
Sbjct: 1485 ---SPPTTTTTTPPPTTTPSP-PTTTPITPPASTTTLP-------PTTTPSPPTTTTTTP 1533
Query: 492 PVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKP 551
P + P+ P P + PPT P P P P P + + P
Sbjct: 1534 PPTTTPSPPTTTP-------------ITPPTSTTTLP-------PTTTPSPPPTTTTTPP 1573
Query: 552 PNGFSSNGENFIPNAP 567
P S P+ P
Sbjct: 1574 PTTTPSPPTTTTPSPP 1589
Score = 54.7 bits (130), Expect = 4e-07
Identities = 52/242 (21%), Positives = 77/242 (31%), Gaps = 26/242 (10%)
Query: 358 TPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPH 417
TP+ P + PP + L PP + P T P P
Sbjct: 1398 TPSPPTTTPSPPPTSTTTL--PPTTTPSPPTTTTTTPPP--------------------- 1434
Query: 418 HASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLP 477
+ P+ P++ P P P + T P P SP PS PT +PP
Sbjct: 1435 -TTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTP--SPPTTTPSPPTTTPSPPTTTT 1491
Query: 478 PPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPI 537
PP PS P P +P P+ PPPT P P+ P
Sbjct: 1492 TTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT 1551
Query: 538 PIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADS 597
P + S PP ++ P+ P + + + + P + + + +
Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611
Query: 598 PP 599
PP
Sbjct: 1612 PP 1613
Score = 54.7 bits (130), Expect = 4e-07
Identities = 86/389 (22%), Positives = 127/389 (32%), Gaps = 51/389 (13%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 3915 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 3971 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4027
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 4028 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 4086
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 4087 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4144
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFI 563
P+ P+ T+ P P P PI V+ + P G +
Sbjct: 4145 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTGPPTHT 4201
Query: 564 PNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADS-------PPGCSGQALSLAPTP---- 612
AP + P S +P+ S+ SS +S PP + + TP
Sbjct: 4202 STAP-IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT 4260
Query: 613 AEHGRSEVVDLTRRAGSPPGPPGAGGQLG 641
G + SPPG P G G
Sbjct: 4261 TTSGGHTLSPPPSTTTSPPGTPTRGTTTG 4289
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 2075 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 2131 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 2188 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 2246
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 2247 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2304
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 2305 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2350
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 2259 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 2315 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2371
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 2372 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 2430
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 2431 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2488
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 2489 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2534
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 2443 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 2499 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 2556 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 2614
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 2615 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2672
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 2673 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2718
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 2627 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 2683 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2739
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 2740 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 2798
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 2799 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2856
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 2857 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2902
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 2811 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 2867 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 2982
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 2983 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3040
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 3041 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3086
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 2995 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 3051 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3107
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 3108 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 3166
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 3167 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3224
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 3225 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3270
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 3179 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 3235 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3291
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 3292 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 3350
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 3351 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3408
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 3409 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3454
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 3363 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 3419 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3475
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 3476 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 3534
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 3535 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3592
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 3593 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3638
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 3547 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 3603 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3659
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 3660 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 3718
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 3719 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3776
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 3777 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3822
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 45/288 (15%)
Query: 290 TGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN--------- 339
TG Q T P+T P+P T Q+ P + +TTV+P+ T
Sbjct: 3731 TGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3786
Query: 340 --CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVP 394
+ T PTP P ++TP P++ + P P G P +P T P P
Sbjct: 3787 ITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3843
Query: 395 LPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMH 452
P + I P + +P + P+ + P P PT++P+
Sbjct: 3844 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI- 3902
Query: 453 RPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
+ + P TPT P + P P P P + P P P
Sbjct: 3903 --TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3960
Query: 505 QMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
P+ P+ T+ P P P PI P P P
Sbjct: 3961 --TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4006
Score = 45.8 bits (107), Expect = 2e-04
Identities = 61/275 (22%), Positives = 91/275 (33%), Gaps = 41/275 (14%)
Query: 303 PLTDARRKAPSPVATAGQSQGPGP-SASTTVSPSDTAN-----------CSVTKIPTPVP 350
P+T P+P T Q+ P + +TTV+P+ T + T PTP P
Sbjct: 1900 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1959
Query: 351 KSIPISETPNIPPVSVQPPASIGP-PLG--VPPRSPPMVMTNRGPVPLPIFMEQQIMQQI 407
++TP P++ + P P G P +P T P P P + I
Sbjct: 1960 TG---TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2016
Query: 408 RPPFIRGPPHHASNPNSPLSNPM--LPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPST 465
P + +P + P+ + P P PT++P+ + + P T
Sbjct: 2017 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI---TTTTTVTPTPT 2073
Query: 466 PTMPGNP--------PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPL 517
PT P + P P P P + P P P P+ P+
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPI 2131
Query: 518 VPPPTLL-VPYPVIVPLPVPIPI-------PIPIP 544
T+ P P P PI P P P
Sbjct: 2132 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2166
Score = 42.0 bits (97), Expect = 0.002
Identities = 52/246 (21%), Positives = 79/246 (32%), Gaps = 29/246 (11%)
Query: 317 TAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPL 376
T ++ P P +T ++ + T + T T P + PI+ T + P P G
Sbjct: 1886 TTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT----PTPTGTQ- 1940
Query: 377 GVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPM--LPGI 434
P +P T P P P + I P + +P + P+ +
Sbjct: 1941 -TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1999
Query: 435 GPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNP--------PGLLPPPPPGAPLP 486
P P PT++P+ + + P TPT P + P P P
Sbjct: 2000 TPTPTPTGTQTPTTTPI---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2056
Query: 487 SLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLL-VPYPVIVPLPVPIPI------ 539
P + P P P P+ P+ T+ P P P PI
Sbjct: 2057 PTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2114
Query: 540 -PIPIP 544
P P P
Sbjct: 2115 TPTPTP 2120
Score = 38.9 bits (89), Expect = 0.021
Identities = 34/145 (23%), Positives = 50/145 (34%), Gaps = 11/145 (7%)
Query: 460 IHPPSTPTMPGNPP-----GLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSL 514
I PS PT +PP L P P P + PP + P+ P+ P+
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP---PTT 1452
Query: 515 APLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAG 574
P P T P P P P P P P + PP ++ +P +
Sbjct: 1453 TPSPPISTTTTPPPTTTPSP---PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509
Query: 575 GKPSGHSLSPRDSKQGSSKSADSPP 599
S +L P + + + +PP
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPP 1534
Score = 33.5 bits (75), Expect = 0.88
Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 5/88 (5%)
Query: 303 PLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIP 362
P T +P+ ++ + PS++TT SP T + + TP P P + +P
Sbjct: 1692 PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSP---PTTTMTTLP 1748
Query: 363 PVSVQPPASIG--PPLGVPPRSPPMVMT 388
P + P + PP PP P T
Sbjct: 1749 PTTTSSPLTTTPLPPSITPPTFSPFSTT 1776
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 83.6 bits (205), Expect = 7e-16
Identities = 103/332 (31%), Positives = 126/332 (37%), Gaps = 59/332 (17%)
Query: 348 PVPKSIPISETPNIPPVSV-QPPASIG--------PPL---GVPPRSPPMVMTNRGPVPL 395
P P +P P +P ++ QPP G PPL G+PP P + G +PL
Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPP---LPGAGILPL 934
Query: 396 PIFMEQQIMQQIRPPFIRG----PPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPM 451
P I PP + G PP PL P LPG G PP P L P
Sbjct: 935 PPLPGAGIPP---PPPLPGAAIPPPPPLPGAGIPLP-PPLPGAGIPP--PPPLPGAGIPP 988
Query: 452 HRPMLSPHIHPPSTPTMPGNPPGLLPPPP-PGA------PLPSLPFPPVSMMPN-GPMPV 503
P+ I PP P +PG G+ PPPP PGA PLP PP +P G P
Sbjct: 989 PPPLPGAGIPPP--PPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1044
Query: 504 PQMMNFGLPSLAPL----VPPPTLLVPYPVIVPLPVP---IPIPIPIPHVSDSKPPNGFS 556
P + G+P PL +PPP L + P P+P IP P P+P + PP
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLP 1103
Query: 557 SNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHG 616
G P PG G + P G A PP + + P P G
Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG----AGIPPPPPLPRVGIPPPPPLPG 1159
Query: 617 RSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQG 648
AG PP PP G + P L G
Sbjct: 1160 ----------AGIPPPPPLPGAGIPPPPPLPG 1181
Score = 80.5 bits (197), Expect = 6e-15
Identities = 83/266 (31%), Positives = 109/266 (40%), Gaps = 40/266 (15%)
Query: 303 PLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIP 362
PL A P P+ AG P P + P + P P+P + I P +P
Sbjct: 1024 PLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPPPPPLP 1081
Query: 363 PVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNP 422
+ PP + P G+PP P + P PLP I PP PP +
Sbjct: 1082 GAGIPPPPPL-PGAGIPPPPPLPGVGIPPPPPLP-------GAGIPPP----PPLPGAGI 1129
Query: 423 NSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGN----PPGL--- 475
P P LPG G PP P L P P+ I PP P +PG PP L
Sbjct: 1130 PPP---PPLPGAGIPPPPP--LPRVGIPPPPPLPGAGIPPP--PPLPGAGIPPPPPLPGV 1182
Query: 476 -LPPPPPGAPLPSLPFPPVSMMPN-GPMPVPQMMNFGL-PSLAPLVPPPTLLVPYPVIVP 532
+PPPP PLP + PP +P G P P + G+ P+ AP +PPP +P P ++P
Sbjct: 1183 GIPPPP---PLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLP 1239
Query: 533 LPVPIPIP------IPIPHVSDSKPP 552
+ P +P +P P V PP
Sbjct: 1240 VSGPPLLPQVGSSTLPTPQVCGFLPP 1265
Score = 78.6 bits (192), Expect = 2e-14
Identities = 106/370 (28%), Positives = 139/370 (37%), Gaps = 46/370 (12%)
Query: 312 PSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPAS 371
PS + +AGQ Q PG ++S ++ + + S I P+ PP+ +S
Sbjct: 814 PSLLWSAGQGQ-PGSQPPHSIS-TEFQTSHEHSVSSAFKNSCNI---PSPPPLPCTESSS 868
Query: 372 IGPPLGVPPRSPPMVMTNRGP------VPLPIFMEQQIMQQIRPPFIRG---PPHHASNP 422
P LG+ P PP + P +P P ++ M PP + G PP
Sbjct: 869 SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPG 928
Query: 423 NSPLSNPMLPGIGPPP---------GGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPP 473
L P LPG G PP P L P+ P+ I PP P +PG
Sbjct: 929 AGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP--PPLPG--A 984
Query: 474 GLLPPPP-PGA------PLPSLPFPPVSMMPN-GPMPVPQMMNFGLPSLAPL----VPPP 521
G+ PPPP PGA PLP PP +P G P P + G+P PL +PPP
Sbjct: 985 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1044
Query: 522 TLLVPYPVIVPLPVP---IPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPS 578
L + P P+P IP P P+P + PP G P PG
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1103
Query: 579 GHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGG 638
G + P G+ PP G + P G L R G PP PP G
Sbjct: 1104 GVGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-RVGIPPPPPLPGA 1160
Query: 639 QLGFPGVLQG 648
+ P L G
Sbjct: 1161 GIPPPPPLPG 1170
Score = 67.8 bits (164), Expect = 4e-11
Identities = 73/229 (31%), Positives = 89/229 (38%), Gaps = 35/229 (15%)
Query: 303 PLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIP 362
PL A P P+ AG P P + P + P P+P + I P +P
Sbjct: 1057 PLPGAGIPPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLP 1114
Query: 363 PVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASN- 421
+ PP + P G+PP P P PLP I PP PP +
Sbjct: 1115 GAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLP-------RVGIPPP----PPLPGAGI 1162
Query: 422 -PNSPLSN------PMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGN--P 472
P PL P LPG+G PP P L P P+ I PP P +PG P
Sbjct: 1163 PPPPPLPGAGIPPPPPLPGVGIPPPPP--LPGVGIPPPPPLPGAGIPPP--PPLPGMGIP 1218
Query: 473 PGLLPP-PPPGAPLPSLPFPPVSMMPNGP------MPVPQMMNFGLPSL 514
P PP PPPG +P P PVS P P +P PQ+ F P L
Sbjct: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267
Score = 47.0 bits (110), Expect = 8e-05
Identities = 67/246 (27%), Positives = 86/246 (34%), Gaps = 40/246 (16%)
Query: 422 PNSPLSNPMLPGIGPPPGGPRNLG---PTSSPMHR---PMLSPHIHPPSTPTMPGNPPGL 475
P +S P PPP + G P S P H + H H S+ N +
Sbjct: 803 PTQSISQPP-----PPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFK--NSCNI 855
Query: 476 LPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPP----TLLVPYPVIV 531
PPP S P + M+P P P+P M LPS A PPP +L P P +
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 532 P---LPVPIPIP----IPIPHVSDS--KPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSL 582
P +P P P+P +P+P + + PP P PG G +
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975
Query: 583 SPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGF 642
P G A PP + P P G AG PP PP G +
Sbjct: 976 PPPPPLPG----AGIPPPPPLPGAGIPPPPPLPG----------AGIPPPPPLPGAGIPP 1021
Query: 643 PGVLQG 648
P L G
Sbjct: 1022 PPPLPG 1027
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 82.4 bits (202), Expect = 2e-15
Identities = 156/643 (24%), Positives = 218/643 (33%), Gaps = 97/643 (15%)
Query: 261 DIFYKETQANLPAGLCSTLHP----PMENKAEGTGV-------QLLTPDSWNIPLTDARR 309
D Y Q G +++ P P++ +A+ G QL P + +PL
Sbjct: 386 DALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE 445
Query: 310 KAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVS---V 366
++P P P AS P + S +P + S P+ E+P PP +
Sbjct: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPAS--PLPEALHLSRPLEESPLSPPPEESPL 503
Query: 367 QPPASIGP--PLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGP--PHHASNP 422
PP P PL P SPP + P+ + + PPF P P P
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA-SPLSPPFEESPLSPPPEELP 562
Query: 423 NSPLSNPMLPGIGPPPG-GPRNLGPTSSPMHRPMLSPHIHPP--STPTMPGNPPGLLPPP 479
SP P + PPP P + P SPM P + + PP +P P L PP
Sbjct: 563 TSP--PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP 620
Query: 480 PPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTL--LVPYPVIVPL-PVP 536
P + L P + PM P P +P+ PPP + L P PV+ L P P
Sbjct: 621 PEASRLSPPP-------EDSPMSPP-------PEESPMSPPPEVSRLSPLPVVSRLSPPP 666
Query: 537 IPIPI-PIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSA 595
P+ P P S + PP S + P DS + + P + S
Sbjct: 667 EESPLSPPPEESPTSPPPEASR-----LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE 721
Query: 596 DSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSP-----PGPPGAGGQLGFPGVLQGPQ 650
+SP L L P RSE L+ R P P P Q P + P+
Sbjct: 722 ESP------LLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPE 775
Query: 651 DGVIDLTVGHRARLHNVIHRALHAHVKAE---REPSAAERRTCGGCRDGHCSP----PAA 703
+ + + H +AE P E + H SP P
Sbjct: 776 EPCL-----------CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824
Query: 704 GDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEP 763
+ P++ C R + + E PP P P PP P + +PE
Sbjct: 825 SPQPEESHLSPQSEEPC----LSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE-- 878
Query: 764 AVSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPK 823
EL S L GE A GE L+ + P +P+ E M P
Sbjct: 879 ---ELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELP--LSPSGEPSLSPQLMPPD 933
Query: 824 TGCVIQPVPKPAEKAAMAPCI-----ISSPMLSAGPEDLEPPL 861
+ P P AA P + + P + G D E PL
Sbjct: 934 P---LPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPL 973
Score = 75.9 bits (185), Expect = 2e-13
Identities = 136/572 (23%), Positives = 185/572 (32%), Gaps = 103/572 (18%)
Query: 272 PAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLT---DARRKAPSPVATA------GQSQ 322
P S L PP E L+P +P + +A R +P P +
Sbjct: 538 PPPEASPLSPPFEESP-------LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPM 590
Query: 323 GPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPAS-IGPPLGVPPR 381
P P AS P + + S P P+ P+S P +S P S + PP P
Sbjct: 591 SPPPEASRLFPPFEESPLS------PPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPM 644
Query: 382 SPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGP--PHHASNPNSPLSNPMLPGIGPPPG 439
SPP ++ P+P ++ ++ PP P P +P SP P + PPP
Sbjct: 645 SPPPEVSRLSPLP--------VVSRLSPPPEESPLSPPPEESPTSP--PPEASRLSPPPE 694
Query: 440 GPRNLGPTSSPMHRPMLSPHIHPP--STPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMP 497
PTS P P SP PP S ++P LLP P P P +S P
Sbjct: 695 D----SPTSPP---PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747
Query: 498 NGPMPVPQMMNFGL------PSLAPLVPPPTLLV----PY-------PVIVPLPVPIPIP 540
P P+ L P L+P P L P+ P + P P + +
Sbjct: 748 EEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS 807
Query: 541 IPI--PHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSP 598
PH+S S E + + +P LSP K S + P
Sbjct: 808 PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP 867
Query: 599 PGCSGQA-----LSLAPTPAEHGRSEVVD--LTRRAGSPP-------------GPPGAGG 638
P GQ L L P P E S ++ G PP G P
Sbjct: 868 PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927
Query: 639 QLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTC-------- 690
QL P L P +I T L + K + +P +
Sbjct: 928 QLMPPDPLPPPLSPII--TAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPP 985
Query: 691 --GGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPP 748
C D PP P PG+P GP + + PP Q PP
Sbjct: 986 PEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP 1045
Query: 749 PPPAPPKKLLSP--------EEPAVSELESVK 772
P LSP +E + E+E+ K
Sbjct: 1046 ALPLSVPSPLSPIGKVVGVSDEAELHEMETEK 1077
Score = 67.4 bits (163), Expect = 6e-11
Identities = 113/504 (22%), Positives = 177/504 (35%), Gaps = 55/504 (10%)
Query: 283 MENKAEGT---GVQLLTPDSWNIPLTD-ARRKAPSPVATAGQSQGPGPSASTTVSPSDTA 338
+++ + GT G++L TPD + PLT A + P + Q P P+ + SP
Sbjct: 2307 VDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHP 2366
Query: 339 NCSVTKIPTPVPKSIPISETPNIPPVS---VQPPASI-GPPLGVPPRSPPMVMTNRGPV- 393
+ T P++ P PP PP S+ P P SP +++ P+
Sbjct: 2367 DIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426
Query: 394 PLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLS-NPMLPGIGPPPGGPRNLGPTSSPMH 452
P P+ E + P F + P ++ P+ P S +P P PP P + + +
Sbjct: 2427 PRPLSAEAFCPSPVTPRF-QSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLA 2485
Query: 453 RPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPV----PQMMN 508
L P + P P L P G P + P P P+ PQ +
Sbjct: 2486 HTSLGAGGFPAALPAGPAGE--LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAV- 2542
Query: 509 FGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPG 568
G PSL P VP P L P+ + P P + + N + G NF P+
Sbjct: 2543 -GEPSLKPPVPQPGLPPPHGINSHFG-------PGPTLGKPQSTNYTVATG-NFHPSGSP 2593
Query: 569 DSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAG 628
++G + LSP S PP G L+ HG S+ +T
Sbjct: 2594 LGPSSGSTGESYGLSPL-----RPPSVLPPPAPDGSLPYLS-----HGASQRSGITSPVE 2643
Query: 629 SPPGP-PGAGGQLG---FPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSA 684
P G G L PG G+ + + + + R L + +R
Sbjct: 2644 KREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRL--RELLIRQQIQRNTLR 2701
Query: 685 AERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAE----- 739
E+ T G PP + P +PA + + ++ G ++
Sbjct: 2702 QEKETAAAAA-GAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPI 2760
Query: 740 ------PPPEQPPPPPPPAPPKKL 757
P ++ PPPPA P +
Sbjct: 2761 LGPGSFPSDDRLSRPPPPATPSSM 2784
Score = 57.4 bits (137), Expect = 6e-08
Identities = 116/480 (24%), Positives = 163/480 (33%), Gaps = 104/480 (21%)
Query: 347 TPVPKSIPISETPNIPPVSVQPPAS-IGPPLGVPPRSP----PMVMTNRGPVP--LPIFM 399
+P P+ +S P +S +P S + P L PP SP P + P P LP+F
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF- 883
Query: 400 EQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPH 459
PP + + L P L G PP P SP P LSP
Sbjct: 884 ---------------PPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQ 928
Query: 460 IHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFP---PVSMMPNGPMPVPQMMNFGLPSLAP 516
+ PP P +P PP +PL L +P P P+ P + P
Sbjct: 929 LMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILE-------TP 981
Query: 517 LVPPP----TLLVPYPVIVPLPVP-IPIPIPIPHVSDSKPPNGFSSNGENFIP-NAPGDS 570
+ PPP T P P ++ P P P+ P + + PP + +P N+P
Sbjct: 982 ISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQ 1041
Query: 571 AAAGGKPSG--HSLSPRDSKQGSSKSAD---------SPPGCSGQALSLAPTPAEHGRSE 619
+ P LSP G S A+ S P C +L P+ S
Sbjct: 1042 CSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECP----ALEPSATSPLPSP 1097
Query: 620 VVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAE 679
+ DL+ A P P A G P DG+ ++
Sbjct: 1098 MGDLSCPA---PSPAPALDDFSGLGEDTAPLDGI--------------------DAPGSQ 1134
Query: 680 REPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGP-EAAAACNVIVNGTRGAAAEGAKSA 738
EP +T G P DP AP P E C + A +G+
Sbjct: 1135 PEPG----QTPGSLASELKGSPVLLDPEELAPVTPMEVYPEC-------KQTAGQGSPCE 1183
Query: 739 EPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEALAG 798
E E+P P P PP + S V+E+ ++ + G+A+ G E L G
Sbjct: 1184 E--QEEPRAPVAPTPPTLIKS---DIVNEISNLSQ----------GDASASFPGSEPLLG 1228
Score = 50.4 bits (119), Expect = 7e-06
Identities = 87/360 (24%), Positives = 119/360 (33%), Gaps = 52/360 (14%)
Query: 311 APSPVATAGQSQGPG---PSASTTVSPSDTANCSVTKIPTPVPK-----SIPISETPNIP 362
AP+ G S PG P T P + T P P+ ++ + E+P +
Sbjct: 2205 APAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG 2264
Query: 363 PVSVQPPASIGPPLGVPPR------------SPPMVMTNRGPVPLPIFMEQQIMQQIRPP 410
P PP G + SP N G V P +++ P
Sbjct: 2265 GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTP 2324
Query: 411 FIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPG 470
+ P P + P PG+G P P P + P P I P + T P
Sbjct: 2325 DVFKAP---LTPRASQVEPQSPGLGLRPQEPP---PAQALAPSPPSHPDIFRPGSYTDPY 2378
Query: 471 NPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVI 530
P L P P P P PP S+ + VP S +PL P P +
Sbjct: 2379 AQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP---LSAEAF 2435
Query: 531 VPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQG 590
P PV P P+ S+PP+ S D A KP K G
Sbjct: 2436 CPSPVTPRFQSPDPY---SRPPSRPQSR----------DPFAPLHKPPRPQPPEVAFKAG 2482
Query: 591 SSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPG---PPGAGGQLGFPGVLQ 647
S A + G G +L PA ++V +G PP PG G +G P ++
Sbjct: 2483 S--LAHTSLGAGGFPAALPAGPAGELHAKV-----PSGQPPNFVRSPGTGAFVGTPSPMR 2535
Score = 48.5 bits (114), Expect = 3e-05
Identities = 115/495 (23%), Positives = 157/495 (31%), Gaps = 120/495 (24%)
Query: 313 SPVATAGQSQGPG----PSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPV-SVQ 367
SP AG S P A + P D+ K+P VP +P + + P ++
Sbjct: 2128 SPTTPAGLSTSADGFLKPPAGSVPGP-DSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE 2186
Query: 368 PPASIGPPLGVP-------PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHAS 420
P PP P P PPM+ + P Q PP G P H
Sbjct: 2187 PRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA-----GQPGEFHTTPP---GTPRHQP 2238
Query: 421 NPNSP-----------LSNPMLPGIG----------PPPGGP---------RNLGPTSSP 450
+ P L+ P PG+G PPP G LG SSP
Sbjct: 2239 STPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELG-ASSP 2297
Query: 451 MHRPMLSPHIHPPSTPTMPGN-----PPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQ 505
+ P + PS+ T G P P P A P + + P P P Q
Sbjct: 2298 SYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPA-Q 2356
Query: 506 MMNFGLPSLAPLVPPPTLLVPY--PVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFI 563
+ PS + P + PY P + P P P P P + PP S+ + +
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP-----PESCCALPPRSLPSDPFSRV 2411
Query: 564 PNAPGDSAAAGGKPSGHSLS-------PRDSKQGSSKSADSPPGCSGQALSLAPTPAEHG 616
P +P +++ + LS P + S PP AP +
Sbjct: 2412 PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLH-KPP 2470
Query: 617 RSEVVDLTRRAGSPPGPP-GAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAH 675
R + ++ +AGS GAGG FP L G LHA
Sbjct: 2471 RPQPPEVAFKAGSLAHTSLGAGG---FPAALPAGPAG------------------ELHAK 2509
Query: 676 VKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGA 735
V + + P+ G G P P P+A G
Sbjct: 2510 VPSGQPPNFVRSPGTGAF---------VGTPSPMRFTFPQAV----------------GE 2544
Query: 736 KSAEPPPEQPPPPPP 750
S +PP QP PPP
Sbjct: 2545 PSLKPPVPQPGLPPP 2559
Score = 43.5 bits (101), Expect = 9e-04
Identities = 75/287 (26%), Positives = 96/287 (33%), Gaps = 59/287 (20%)
Query: 277 STLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSD 336
+TL E A G + P SW PS A S+G P A T S
Sbjct: 2698 NTLRQEKETAAAAAGA-VGPPGSWGAE--------PSSPAFEQLSRGQTPFAGTQ-DKSS 2747
Query: 337 TANCSVTKIPTPV--PKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMV-----MTN 389
+K+ P+ P S P + + PP PPA+ P + S +V
Sbjct: 2748 LVGLPPSKLSGPILGPGSFPSDDRLSRPP----PPAT---PSSMDVNSRQLVGGSQAFYQ 2800
Query: 390 RGPVP--LPIFMEQQIMQQ---------------IRPPFIRGPPHHASNPNSPLS--NPM 430
R P P LP+ +QQ + Q R P GP SPL+ +
Sbjct: 2801 RAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTR 2860
Query: 431 LPGIGPPPGGP--------------RNLGPTSSPM--HRPMLSPHIHPPSTPTMPGNPPG 474
LPG G P GP + LGP +P P P +P S P G
Sbjct: 2861 LPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEG 2920
Query: 475 LLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPP 521
L G P PP + N P P LP+ LV P
Sbjct: 2921 LRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRP 2967
Score = 42.4 bits (98), Expect = 0.002
Identities = 80/328 (24%), Positives = 112/328 (34%), Gaps = 31/328 (9%)
Query: 346 PTPVPKSIPISET-PNIPPVSVQPPASI--GPPLGVPPRSPPMV-MTNRGPVPLPIFMEQ 401
P P PK P+ ++ +P V + P GV ++P + ++ + L + Q
Sbjct: 4170 PQP-PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQ 4228
Query: 402 QIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIH 461
+ +QQ + P SPL L G P GG GP + P+ P
Sbjct: 4229 RQLQQSQAVRQTPPYQEPGTQTSPLQG--LLGCQPQLGGFP--GPQTGPLQELGAGPR-- 4282
Query: 462 PPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPP 521
P PP L P PPGA PV P P LPS + +P
Sbjct: 4283 -------PQGPPRL--PAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTE 4333
Query: 522 TLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHS 581
L P P P + P VS + + + P P D+ A KP S
Sbjct: 4334 AQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSS 4393
Query: 582 LSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRA--GSPPGPPGAGGQ 639
L P Q + + LS+ P E + +R G P G PG
Sbjct: 4394 LVPGHLDQVNGQVVP-----EASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNH 4448
Query: 640 LGFPGVLQGPQDGVIDLTVGHRARLHNV 667
L +L GP+ L + R NV
Sbjct: 4449 L----LLAGPRSEAGHLLLQKLLRAKNV 4472
Score = 36.2 bits (82), Expect = 0.14
Identities = 14/26 (53%), Positives = 15/26 (57%)
Query: 740 PPPEQPPPPPPPAPPKKLLSPEEPAV 765
PPPE+P PPP P P P EP V
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLV 4934
Score = 33.5 bits (75), Expect = 0.88
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 462 PPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVP 504
PP P+ P +P P PP PL LP P++ P P P+P
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA-EPPVPSPLP 4951
Score = 30.0 bits (66), Expect = 9.8
Identities = 29/79 (36%), Positives = 31/79 (39%), Gaps = 18/79 (22%)
Query: 483 APLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPT-LLVPYPVIVPLPV------ 535
AP P P PP S P P P P PLV PT L PV PLP+
Sbjct: 4908 APPPEEPSPPPS--PLAPSPAS-------PPTEPLVELPTEPLAEPPVPSPLPLASSPES 4958
Query: 536 --PIPIPIPIPHVSDSKPP 552
P P P DS+PP
Sbjct: 4959 ARPKPRARPPEEGEDSRPP 4977
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 82.4 bits (202), Expect = 2e-15
Identities = 135/536 (25%), Positives = 178/536 (33%), Gaps = 111/536 (20%)
Query: 282 PMENKAEGTGVQLLTPDSWNIPLT---DARRKAPSPVATAGQSQGPGPSASTTVSPSDTA 338
P E + E + + + + + P D R +PS + SA + +
Sbjct: 126 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185
Query: 339 NCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRS--PPMVMTNRGPVPLP 396
TP P S P TP +P P A+ PP G P S P PVP
Sbjct: 186 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 244
Query: 397 IFMEQQIMQQIRPPFIRGPPH------------HASNPNSPL-SNPMLPGIGPPPGGPRN 443
+ + RPP PPH A P++P + P L G GPP GP +
Sbjct: 245 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP--GPHS 302
Query: 444 LGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPV 503
L P + P P G PP P P+ +P S+ P
Sbjct: 303 L----------QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL--PASQ 350
Query: 504 PQMMNFGLPSLAPLVPPPTLLVPY---PVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGE 560
+ + P PL PP L +P+ P P+P +P P H P+ FS N
Sbjct: 351 SALQSQQPPREQPL-PPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPFSMNAN 408
Query: 561 NFIPNA--PGDSAAAGGKPSGHS--LSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHG 616
P A P S + PS H L Q S PPG + Q+ +L P PA H
Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT-QSQNLPPPPASHP 467
Query: 617 RSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHV 676
+ + + P PP A P V GP +
Sbjct: 468 PTGLHQVA------PQPPFAQ----HPFVPGGPPP------------------------I 493
Query: 677 KAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPE---AAAACNVIVNG------T 727
PS + +PPA GPG A P AAA+ I G T
Sbjct: 494 TPPTCPSTS-------------TPPA----GPGTSAQPPCSGAAASGGSIAGGSSCPLPT 536
Query: 728 RGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLD 783
E AE P PPPP P+P EP V + S + HLD
Sbjct: 537 VQIKEEALDDAEEPESPPPPPRSPSP--------EPTVVDTPSHASQSARFYKHLD 584
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 82.4 bits (202), Expect = 2e-15
Identities = 135/536 (25%), Positives = 178/536 (33%), Gaps = 111/536 (20%)
Query: 282 PMENKAEGTGVQLLTPDSWNIPLT---DARRKAPSPVATAGQSQGPGPSASTTVSPSDTA 338
P E + E + + + + + P D R +PS + SA + +
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739
Query: 339 NCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRS--PPMVMTNRGPVPLP 396
TP P S P TP +P P A+ PP G P S P PVP
Sbjct: 740 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798
Query: 397 IFMEQQIMQQIRPPFIRGPPH------------HASNPNSPL-SNPMLPGIGPPPGGPRN 443
+ + RPP PPH A P++P + P L G GPP GP +
Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP--GPHS 856
Query: 444 LGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPV 503
L P + P P G PP P P+ +P S+ P
Sbjct: 857 L----------QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL--PASQ 904
Query: 504 PQMMNFGLPSLAPLVPPPTLLVPY---PVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGE 560
+ + P PL PP L +P+ P P+P +P P H P+ FS N
Sbjct: 905 SALQSQQPPREQPL-PPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPFSMNAN 962
Query: 561 NFIPNA--PGDSAAAGGKPSGHS--LSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHG 616
P A P S + PS H L Q S PPG + Q+ +L P PA H
Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT-QSQNLPPPPASHP 1021
Query: 617 RSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHV 676
+ + + P PP A P V GP +
Sbjct: 1022 PTGLHQVA------PQPPFAQ----HPFVPGGPPP------------------------I 1047
Query: 677 KAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPE---AAAACNVIVNG------T 727
PS + +PPA GPG A P AAA+ I G T
Sbjct: 1048 TPPTCPSTS-------------TPPA----GPGTSAQPPCSGAAASGGSIAGGSSCPLPT 1090
Query: 728 RGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLD 783
E AE P PPPP P+P EP V + S + HLD
Sbjct: 1091 VQIKEEALDDAEEPESPPPPPRSPSP--------EPTVVDTPSHASQSARFYKHLD 1138
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 82.4 bits (202), Expect = 2e-15
Identities = 135/536 (25%), Positives = 178/536 (33%), Gaps = 111/536 (20%)
Query: 282 PMENKAEGTGVQLLTPDSWNIPLT---DARRKAPSPVATAGQSQGPGPSASTTVSPSDTA 338
P E + E + + + + + P D R +PS + SA + +
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739
Query: 339 NCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRS--PPMVMTNRGPVPLP 396
TP P S P TP +P P A+ PP G P S P PVP
Sbjct: 740 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798
Query: 397 IFMEQQIMQQIRPPFIRGPPH------------HASNPNSPL-SNPMLPGIGPPPGGPRN 443
+ + RPP PPH A P++P + P L G GPP GP +
Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP--GPHS 856
Query: 444 LGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPV 503
L P + P P G PP P P+ +P S+ P
Sbjct: 857 L----------QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL--PASQ 904
Query: 504 PQMMNFGLPSLAPLVPPPTLLVPY---PVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGE 560
+ + P PL PP L +P+ P P+P +P P H P+ FS N
Sbjct: 905 SALQSQQPPREQPL-PPAPLAMPHIKPPPTTPIP-QLPAPQAHKHPPHLSGPSPFSMNAN 962
Query: 561 NFIPNA--PGDSAAAGGKPSGHS--LSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHG 616
P A P S + PS H L Q S PPG + Q+ +L P PA H
Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLT-QSQNLPPPPASHP 1021
Query: 617 RSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHV 676
+ + + P PP A P V GP +
Sbjct: 1022 PTGLHQVA------PQPPFAQ----HPFVPGGPPP------------------------I 1047
Query: 677 KAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPE---AAAACNVIVNG------T 727
PS + +PPA GPG A P AAA+ I G T
Sbjct: 1048 TPPTCPSTS-------------TPPA----GPGTSAQPPCSGAAASGGSIAGGSSCPLPT 1090
Query: 728 RGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLD 783
E AE P PPPP P+P EP V + S + HLD
Sbjct: 1091 VQIKEEALDDAEEPESPPPPPRSPSP--------EPTVVDTPSHASQSARFYKHLD 1138
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 82.0 bits (201), Expect = 2e-15
Identities = 140/596 (23%), Positives = 186/596 (31%), Gaps = 95/596 (15%)
Query: 303 PLTDARRKAPSPVATAGQSQGPG----PSASTTVSPSDTANCSVTKIPTPVPKSIPISET 358
P T + + AP P A S G P +P+ T + TP PK P T
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT--T 1151
Query: 359 PNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRG---P 415
P P S + + PP G P + +G + P PP +G
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211
Query: 416 PHHASNPNSPLSNPMLPGIG----PPPGGPRNLGPTS-SPMHRPMLSPHIHPPSTP--TM 468
P P +P + P P G P G P T SP P P P+ P T
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271
Query: 469 PGNPPGLLPPPPPGAPLPSLPFPPV-----SMMPNGPMPVPQMMNFGLPSLAPLVPPPTL 523
P GL PP GAP P++ PP + P P P P +P PPP
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG 1331
Query: 524 LVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNA---PGDSAAAGGKPSGH 580
P + P P P + + P SS G P++ P AA G
Sbjct: 1332 APTPPAVTP---------PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382
Query: 581 SLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQL 640
+++P K+G + P G S A P ++ +TR + P G L
Sbjct: 1383 AMTPPSPKRGPAI-----PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK----GDL 1433
Query: 641 GFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSP 700
P V +K SA + G +
Sbjct: 1434 TPPAVTP--------------------------VSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 701 PAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSA-----EPPPEQPPPPP----PP 751
PA P P P P+ A + A GA + P E P P P
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 752 APPKKLLS--------PEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSD 803
AP LLS P+E + +V EA +EA S
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA------SS 1581
Query: 804 PNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMAPCIISSPMLSAGPEDLEP 859
P PA Y PK + V P+ K A P ++ P GP P
Sbjct: 1582 P----PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633
Score = 79.3 bits (194), Expect = 1e-14
Identities = 130/505 (25%), Positives = 166/505 (32%), Gaps = 74/505 (14%)
Query: 303 PLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIP------TPVPKSIPIS 356
P T + + AP+P A S P+A+ + T + P TP+PK P +
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
Query: 357 ETPNIP-----PVSVQPPASIGPPLGVP--PRSPPMVMTNRGPVPLPIFMEQQIMQQIRP 409
+P P + + PP P P+ P + +G P+P P
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG-APMP--------PAATP 1110
Query: 410 PFIRG---PPHHASNPNSPLSNPMLPGIG----PPPGGPRNLGPT-SSPMHRPMLSPHIH 461
P +G P H P +P + P P G PP G P T SP P
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Query: 462 PPSTP--TMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNF-GLPSLAPLV 518
P+TP T P GL P P GAP PP P G + P P+ P
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPP---SPKGGLATPSPKGAPTTPAATPPS 1227
Query: 519 PPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAA--GGK 576
P L P P P P P + PP G + P+ G A G
Sbjct: 1228 PKGGLATPSPKGAP-TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286
Query: 577 PSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPG--PP 634
P+ ++P K G A SPP G A TP S + A +PP PP
Sbjct: 1287 PNPAVVTPPSPKGG---PATSPP--KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Query: 635 GAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCR 694
G P + G T + H A PS +
Sbjct: 1342 SPKGTPTLPATTPSSKGG--PTTPSSKEGPTPPAATPSHKGGPAMTPPSP---------K 1390
Query: 695 DGHCSPPAAGDPGPGA--PAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPP------ 746
G P GDP A P P+ A A V TR AA +K PP P
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPV----TREGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 747 -----PPPPPAPPKKLLSPEEPAVS 766
P PA P P PAV+
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVT 1471
Score = 74.7 bits (182), Expect = 3e-13
Identities = 144/641 (22%), Positives = 200/641 (31%), Gaps = 102/641 (15%)
Query: 267 TQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQ---- 322
T +L GL + H N A T P P T + AP+P A S
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVT-----PPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 323 -------GPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPP 375
P P A T SP T T + + P S+ PP + P GP
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT-PSHKGGPA 1383
Query: 376 LGVP-PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPN---------SP 425
+ P P+ P + + +G P + + P R A+ P+ +P
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR---EGAATPSKGDLTPPAVTP 1440
Query: 426 LSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTM--PGNPPGLLPPPPPGA 483
+S P P GGP P + P P P + P P P
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500
Query: 484 PLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVP-----PPTLLVPYPVIVPLPVPIP 538
P+LP +++P+ P VP + +AP P L P ++P + +P
Sbjct: 1501 GAPTLP----AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 539 IPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSP 598
P P + K S+ E P A S G L P S K A +P
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Query: 599 PGCSGQALSLAP-TPAEHGR--SEVVDLTRRAGSPPGP------------------PGAG 637
P + + P TPA G S V + SP P P
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676
Query: 638 GQLGFPGVL----------------QGPQDGVIDLT---VGHRARLHNVIHRALHAHVKA 678
G VL +GPQ T + N L A
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736
Query: 679 EREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSA 738
P + +D SP P + P AAA ++ A+ A S
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS- 1795
Query: 739 EPPPEQP--PPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEAL 796
PP P P P P PPK+ P P + V E+ D + L+ E +
Sbjct: 1796 -PPVSLPLAPSPVPTLPPKQQFLPSSPGL-----VLESPSKPLAPADEDELLPLIPPEPI 1849
Query: 797 AGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEK 837
+GG L N PK+ + PVP P+ K
Sbjct: 1850 SGGVPFQSVLVN----------MPTPKSAGI--PVPTPSAK 1878
Score = 73.2 bits (178), Expect = 1e-12
Identities = 128/537 (23%), Positives = 177/537 (32%), Gaps = 81/537 (15%)
Query: 282 PMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVS--PSDTAN 339
P+E+ A+ GV T + T A V+ A ++ TT+ P+ + N
Sbjct: 649 PLES-ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707
Query: 340 CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFM 399
C V P+P P++ P + P+ PP G PP + + + P+
Sbjct: 708 CPVA--PSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765
Query: 400 E-----QQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPP-----GGP----RNLG 445
+ +G + ++ SPL + P PP GP NL
Sbjct: 766 SPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLS 825
Query: 446 PTSSPMHRPMLSPH-IHPPSTPTMPGNPPGLLPPPPPGAPLPS--LPFPPVSM-MPNGPM 501
SP+ L + + + P PP P GAP PS P P + +P
Sbjct: 826 SPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKET 885
Query: 502 PVPQMMNFGLPSLAPLVPPP---------------TLLVPYPVIVPL-PVPIPIPIPIPH 545
P P ++N P P P P P P +P P P P P P
Sbjct: 886 PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP-PA 944
Query: 546 VSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQA 605
+ P G ++ + P P AA P G +P S K A +PP + +
Sbjct: 945 ATPPSPKGGPATPSPKWAPTPP---AATPPSPKGGPATP------SPKGAPTPPAATPPS 995
Query: 606 LSLAP-TPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARL 664
P TP+ G T A +PP P G+ FP P G A
Sbjct: 996 PKGGPATPSPKGAP-----TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA-- 1048
Query: 665 HNVIHRALHAHVKAEREPSAAERRTCGG----CRDGHCSPPAAGDPGP-GAPAGPEAAAA 719
A A P+A GG G +PPAA P P G PA P A
Sbjct: 1049 ------ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102
Query: 720 ----CNVIVNGTRGAAAEGAKSAEPPPEQPP---------PPPPPAPPKKLLSPEEP 763
+ G A K A P P PPP AP +P P
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159
Score = 73.2 bits (178), Expect = 1e-12
Identities = 120/477 (25%), Positives = 149/477 (31%), Gaps = 120/477 (25%)
Query: 307 ARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSV 366
A +P+P + G P PSA T +SP ++P ETP P V
Sbjct: 851 ATTHSPTPPSPKG---APTPSAVTPLSPKGV--------------TLPPKETPT-PSVVN 892
Query: 367 QPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPL 426
P GP P ++P + MT+ P ++ P I P P P
Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSP--------KKARATPAPKGIPASPSPKGAPTPPA 944
Query: 427 SNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLP 486
+ P P GGP P +P P +TP P P P P GAP P
Sbjct: 945 ATPP-----SPKGGPATPSPKWAPTP---------PAATPPSPKGGPAT--PSPKGAPTP 988
Query: 487 SLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHV 546
PP P G P P AP PP + P P P P P P
Sbjct: 989 PAATPP---SPKGGPATPS------PKGAPT--PPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 547 SDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQAL 606
+ P G S AP AA P G +P S K A +PP + +
Sbjct: 1038 ATPPSPKG-SPAATPLPKGAPTTPAATLPSPKGGPATP------SLKGAPTPPAATPPSP 1090
Query: 607 SLAP-TPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLH 665
P TP+ G A +PP P G G+ P G
Sbjct: 1091 KGGPATPSPKGAP-----MPPAATPPSPKG--------GLATPPHKG------------- 1124
Query: 666 NVIHRALHAHVKAEREPSAAERRTCGGCR----DGHCSPPAAGDPGP----------GAP 711
A P+A GG G + PAA P P GAP
Sbjct: 1125 ------------APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172
Query: 712 AGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPP--APPKKLLSPEEPAVS 766
P A + G A K A P PP P A P +P PA +
Sbjct: 1173 TTPAATPP-----SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224
Score = 72.4 bits (176), Expect = 2e-12
Identities = 144/612 (23%), Positives = 200/612 (32%), Gaps = 101/612 (16%)
Query: 294 LLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSI 353
L TP P T A +P + G P P + T +P+ T + TP PK
Sbjct: 1163 LATPPPKGAPTTPAA----TPPSPKGGLATPSPKGAPT-TPAATPPSPKGGLATPSPKGA 1217
Query: 354 PISE--TPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPF 411
P + TP P + P+ G P P +PP + +G P PP
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPT-TPAATPP---SPKGGPATPPPKGAPTPPAATPPS 1273
Query: 412 IRG----PPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPT 467
++G PPH + PN + P P P G GP +SP P PPS
Sbjct: 1274 LKGGLATPPHKGA-PNPAVVTP------PSPKG----GPATSPPKGAPTPPAATPPSPKG 1322
Query: 468 MPG--------NPPGLLPPPPPGAP-LPSL-------PFPPVSMM-PNGPMPVPQ----- 505
PG PP + PP P G P LP+ P P S P P P
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382
Query: 506 MMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGF---SSNGENF 562
M P P +P P P ++PL P+ + P G +
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 563 IPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVD 622
+ AP SA GG + S + S PP A S +P
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP------------ 1490
Query: 623 LTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHR---ARLHNVIHRALHAHVKAE 679
++A + P P GA P V+ V R A ++ + A + A
Sbjct: 1491 --KKAPATPAPMGAP---TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL-AP 1544
Query: 680 REPSAAERRTCGGCRDGHCSPPAAGDP--GPGAPAGPEAAAACNVIVNGTRGA------- 730
+E T + PA P P P+ EA++ V + +GA
Sbjct: 1545 KEALIPPAMTVPSPK----KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600
Query: 731 -----AAEGAKSAEPPPEQPPPPPP--PAPPKKLLSPEEPAV--SELESVKENNCASNCH 781
+ K A PP PP P PA P +P P V S L+ + + C
Sbjct: 1601 IPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Query: 782 LDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCVIQPVPKPAEKAAMA 841
+ + G A G L PA E P + P+ + +A +
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPES-------TPIITAPTRKGPQTKKSSATS 1713
Query: 842 PCIISSPMLSAG 853
P I P G
Sbjct: 1714 PPICPDPSAKNG 1725
Score = 53.5 bits (127), Expect = 8e-07
Identities = 70/327 (21%), Positives = 119/327 (36%), Gaps = 45/327 (13%)
Query: 281 PPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANC 340
PP K T TP S + + + SP + + P AS +
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680
Query: 341 SVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPV----PLP 396
+ P P+S PI P + ++ PP+ P + ++GP+ P P
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK---NGSKGPLSTVAPAP 1737
Query: 397 IFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPML 456
+ Q+ + + +P PL+ PP + T++ + +
Sbjct: 1738 LLPVQKDSSKTAK-----GKDASHSPKGPLA---------PPESKASTPLTAAAFEKVLP 1783
Query: 457 SPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGP-----MPVPQMMNFGL 511
P ++ + +PP LP P +P+P+LP P +P+ P P +
Sbjct: 1784 KPE---SASVSAAPSPPVSLPLAP--SPVPTLP-PKQQFLPSSPGLVLESPSKPLAPADE 1837
Query: 512 PSLAPLVPPPTLL--VPY-PVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPG 568
L PL+PP + VP+ V+V +P P IP+P S +P N G
Sbjct: 1838 DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP----------VTKNNKG 1887
Query: 569 DSAAAGGKPSGHSLSPRDSKQGSSKSA 595
+ S L +DS Q +++ A
Sbjct: 1888 SGTESDSDESVPELEEQDSTQATTQQA 1914
Score = 52.8 bits (125), Expect = 1e-06
Identities = 123/508 (24%), Positives = 167/508 (32%), Gaps = 83/508 (16%)
Query: 314 PVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIP--PVSVQPPAS 371
P + G P + TT T V P P S +P IP P + S
Sbjct: 536 PASLEGAPFSPAQAGLTT-KKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKS 594
Query: 372 IGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPML 431
+G PL P P MT+ PL + + I+ GP S L P +
Sbjct: 595 LGEPL--PIGKPASSMTS----PLGVNSSASV---IKTDSYAGPDSAGPLLKSSLITPTV 645
Query: 432 PGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNP--PGLLPPPPPGAP----- 484
P + PT++ ST T +P G + P P
Sbjct: 646 AAFPLESADPAGVAPTTAK-----------GTSTYTTTASPFLEGTVSLAPKNHPVKEGT 694
Query: 485 LPSLPFPPVSM--MPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIP 542
L +LP P + P P P LAP +P VP P + P P P
Sbjct: 695 LTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKS---VPSPSLPPAGTP-PGTKK 750
Query: 543 IPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGK-----------PSGHSLSPRDSKQGS 591
+ +S + +S+ + G SA A K P G S+SP+ + +
Sbjct: 751 VDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPT 810
Query: 592 SKSADSPPGCSGQALSLAPTPAEHG----------RSEVVDLTRRAGSPPGP-----PGA 636
K + P G LS +P E S+ T + +PP P P A
Sbjct: 811 KKGSAGPDTPIGN-LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
Query: 637 GGQLGFPGVLQGPQD----GVIDLTVGHRARLHNVIHRA-----LHAHVKAEREPSAAER 687
L GV P++ V++L +A + K R A +
Sbjct: 870 VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
Query: 688 RTCGGCRDGHCSPPAAGDPGP-GAPA------GPEAAAACNVIVNGTRGAAAEGAKSAEP 740
G +PPAA P P G PA P AA G G A K A
Sbjct: 930 IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG--GPATPSPKGAPT 987
Query: 741 PPEQPPPPPP--PAPPKKLLSPEEPAVS 766
PP PP P PA P +P PAV+
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVT 1015
Score = 51.6 bits (122), Expect = 3e-06
Identities = 76/327 (23%), Positives = 117/327 (35%), Gaps = 46/327 (14%)
Query: 335 SDTANCSVTKIPTPVPKS--IPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGP 392
++T + ++P P ++ +P+S ++ QP ++ PP P+ P+ N+
Sbjct: 6 TETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS 65
Query: 393 VPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGP--PPGGPRNLGPTSSP 450
P P P I P P S + G P P P +GP SP
Sbjct: 66 -PFP-----------SPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113
Query: 451 MHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFG 510
+ SP I P T + P L P + S FPP +++ + P
Sbjct: 114 AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP-NLLTSPPSVAVAESGSV 172
Query: 511 LPSLAPLVPP---------PTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGEN 561
+ AP+ P P+ +VP P P P I +P V+ P +G
Sbjct: 173 ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVT----PMASIQSGVA 228
Query: 562 FIPNAPGDSAAAGGKP-------SGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAE 614
+P + A P S +SP++ S K SPP ALSL+
Sbjct: 229 SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPA----ALSLSTQSL- 283
Query: 615 HGRSEVVDLTRRAGSPPGPPGAGGQLG 641
VV +++ P PP LG
Sbjct: 284 ----PVVTSSQKTAGPNTPPDFPISLG 306
Score = 41.2 bits (95), Expect = 0.004
Identities = 57/255 (22%), Positives = 92/255 (36%), Gaps = 29/255 (11%)
Query: 311 APSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPN----IPPVSV 366
A PV +GP +S T SPS + N + + +P S+ + +PN P V+
Sbjct: 372 AAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPT-TSLILKSSPNATYHYPLVAQ 430
Query: 367 QPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPL 426
P +S+G + P+V+TN + ++ + PP GP + P SP
Sbjct: 431 MPVSSVG--------TTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNI-EPTSPA 481
Query: 427 SNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPP----G 482
+ M P P ++ + P+ P P +P + P
Sbjct: 482 ALVMAPVAPKEPS-----TQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVP 536
Query: 483 APLPSLPFPP-----VSMMPNGPMPVPQMMNFGLPSLAPLVPPPTL-LVPYPVIVPLPVP 536
A L PF P + +P+ Q PS P + L P + +
Sbjct: 537 ASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLG 596
Query: 537 IPIPIPIPHVSDSKP 551
P+PI P S + P
Sbjct: 597 EPLPIGKPASSMTSP 611
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 81.6 bits (200), Expect = 3e-15
Identities = 94/350 (26%), Positives = 142/350 (40%), Gaps = 46/350 (13%)
Query: 311 APSPVATAGQSQGPGPSASTTVSPSDTANC------SVTKIPTPVPKSIPISETPNIP-- 362
+PSP +A PG + T SP + S IP P + P+S T ++P
Sbjct: 1380 SPSPEVSAS---APGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLS 1436
Query: 363 ---PVSVQP--PASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRP--PFIRGP 415
P+SV PA PL +P S P+ ++ GP L + + P P GP
Sbjct: 1437 SSLPISVPTTLPAPASAPLTIPI-SAPLTVSASGPALLT-----SVTPPLAPVVPAAPGP 1490
Query: 416 PHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSP---HIHPPSTPTMPGNP 472
P A + SP ++ + G+ P +L + +P H +L+P H+ ++ P
Sbjct: 1491 PSLAPSGASPSASALTLGLATAP----SLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACS 1546
Query: 473 PGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLV---PYPV 529
P L+P +P PS P P + P LAP+ P T ++ P P
Sbjct: 1547 PVLVPASALASPFPSAP-NPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPP 1605
Query: 530 IVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHS--LSPRDS 587
+ PLPV P P P ++ S+ P + + PG S A+ + L+P +
Sbjct: 1606 LAPLPVLAPSPGAAPVLASSQTPVPVMAPS-----STPGTSLASASPVPAPTPVLAPSST 1660
Query: 588 KQGSSKSADSP--PGCSGQALSLAPT--PAEHGRSEVVDLTRRAGSPPGP 633
+ SP S Q L+LAP P G S L+ G+P GP
Sbjct: 1661 QTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGP 1710
Score = 72.0 bits (175), Expect = 2e-12
Identities = 88/297 (29%), Positives = 124/297 (41%), Gaps = 38/297 (12%)
Query: 335 SDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVP 394
S A+ ++ + P P P+S P+ P + P + PL + PP ++ N G V
Sbjct: 1252 SQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAA-NQVPPTMVNNTGVV- 1309
Query: 395 LPIFMEQQIMQQIRP-PFIRGPPHHASNPNSPLSNP---MLPGIGPPPGGPRNLGPTSSP 450
I + Q + P P + P S+ + NP + PG P P LG +P
Sbjct: 1310 -KIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTP----TLGTARAP 1364
Query: 451 MHRPM----LSPHIHPPSTPTMPGNPPGLLP---PPPPGAPLPSLPFPPVSMMP---NGP 500
M P L +H PS P + + PG P P P SLP P S MP + P
Sbjct: 1365 MPTPTLVRPLLKLVHSPS-PEVSASAPGAAPLTISSPLHVP-SSLPGPASSPMPIPNSSP 1422
Query: 501 M--PVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPP--NGFS 556
+ PV ++ L S P+ P TL P P PL +PI P+ VS S P +
Sbjct: 1423 LASPVSSTVSVPLSSSLPISVPTTL--PAPASAPLTIPISAPLT---VSASGPALLTSVT 1477
Query: 557 SNGENFIPNAPG--DSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPT 611
+P APG A +G PS +L+ + S S+ +P G L LAPT
Sbjct: 1478 PPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTP----GHPLLLAPT 1530
Score = 53.1 bits (126), Expect = 1e-06
Identities = 113/518 (21%), Positives = 174/518 (33%), Gaps = 104/518 (20%)
Query: 324 PGPSASTTVSPSDTANCSVTKIPTPVPKSIPIS-----ETPNIPPVSV--------QPPA 370
P +A+TT + + TA + PTP P+ + +S P+ VS+ +P A
Sbjct: 1140 PPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVA 1199
Query: 371 SIG--PPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSN 428
+ G PL + + +T L + + + + + G HH + P
Sbjct: 1200 NAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLI--SQPAHV 1257
Query: 429 PMLPGIGPPPG-GPRNLGPTSSPMHRP----MLSPHIHPPSTPTMPGN------------ 471
++ + P PG P ++ P+S+P P + P PTM N
Sbjct: 1258 ALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAP 1317
Query: 472 -------PPGLLPPPPPGAPLPSLPFPPVSMMP-----------NGPMPVPQMM------ 507
PP P PP + LP++ P ++ P PMP P ++
Sbjct: 1318 RDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKL 1377
Query: 508 ----NFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFI 563
+ + + AP P T+ P V LP P P+PIP+ S P +
Sbjct: 1378 VHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASP-------VSST 1430
Query: 564 PNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDL 623
+ P S+ P+ +P + SA SG AL + TP L
Sbjct: 1431 VSVPLSSSLPISVPTTLP-APASAPLTIPISAPLTVSASGPALLTSVTP---------PL 1480
Query: 624 TRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVG---------HRARLHNVIHRALHA 674
+ PGPP G LT+G + H ++ +
Sbjct: 1481 APVVPAAPGPPSLAP--------SGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSS 1532
Query: 675 HVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAP-AGPEAAAACNVIVNGTRGAAAE 733
HV A C A P P AP P A+ + ++ A
Sbjct: 1533 HVPGLNSTVAP------ACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATP 1586
Query: 734 GAKSAEPPPE-QPPPPPPPAPPKKLLSPEEPAVSELES 770
A A P P P PP P +L+P A L S
Sbjct: 1587 LAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLAS 1624
Score = 47.8 bits (112), Expect = 5e-05
Identities = 83/355 (23%), Positives = 118/355 (33%), Gaps = 108/355 (30%)
Query: 317 TAGQSQGPGPSASTTVSPSDTANCSVTK--IPTPVPKSIPISETPNIPPVSVQPPASIGP 374
T G + P SA T S + CS + +P P P+ P TP P ++ PA +
Sbjct: 2406 TQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRP---TPASAPAAI--PALVPV 2460
Query: 375 PLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGI 434
P+ P P A NP + L +LP
Sbjct: 2461 PVSAPV-----------------------------------PISAPNPITILPVHILPSP 2485
Query: 435 GPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPP------PPGAPL--- 485
PP P P SSP P P TP PP PPP P +PL
Sbjct: 2486 PPPSQIP----PCSSPACTP------PPACTP-----PPAHTPPPAQTCLVTPSSPLLLG 2530
Query: 486 -PSLPF-PPVSMMPNGPMPVPQMM--------NFGLPSLAPLVPPPTLLVPYPVIVPLPV 535
PS+P V+ +P G P ++ + L S+A LVP ++P+ V
Sbjct: 2531 PPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAV 2590
Query: 536 PIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGS---- 591
I +P+ S + P+AP + AG P+G DS +G+
Sbjct: 2591 EI-LPV--------------SEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTV 2635
Query: 592 -------------SKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGP 633
S + PP + P A+ E+ + SP P
Sbjct: 2636 LPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKP 2690
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/184 (25%), Positives = 71/184 (38%), Gaps = 59/184 (32%)
Query: 311 APSPVATAGQSQGPGPSASTTVSPSDTANC--------SVTKIPTPVPKSIPIS-ETPNI 361
AP+P GP P+ + T++P+ ++ ++T P PVP P + +T +
Sbjct: 1749 APAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLAL 1808
Query: 362 PPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASN 421
P S Q PAS ++ +V++ G PLP+ M ++ P
Sbjct: 1809 APASTQSPAS---------QASSLVVSASGAAPLPVTMVSRL------------PVSKDE 1847
Query: 422 PNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNP-PGLLPPPP 480
P++ + GPP PPST T G P P PPPP
Sbjct: 1848 PDT-----LTLRSGPPS-----------------------PPSTATSFGGPRPRRQPPPP 1879
Query: 481 PGAP 484
P +P
Sbjct: 1880 PRSP 1883
Score = 45.1 bits (105), Expect = 3e-04
Identities = 129/580 (22%), Positives = 191/580 (32%), Gaps = 107/580 (18%)
Query: 308 RRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPN---IPPV 364
R P + + + P P+ +P+ +P PV +PIS PN I PV
Sbjct: 2421 RSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPIS-APNPITILPV 2479
Query: 365 SVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNP-N 423
+ P S PP +PP S P PP PP H P
Sbjct: 2480 HILP--SPPPPSQIPPCSSPACTP--------------------PPACTPPPAHTPPPAQ 2517
Query: 424 SPLSNPMLPGIGPPPGGPRNLGPTSSPMH-RP--------MLSPH-IHPPSTPTMPGNPP 473
+ L P P + PP P + T+ P+ RP + SP + S + +
Sbjct: 2518 TCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSL 2577
Query: 474 GLLPPP---PPGAPLPSLPFPPVSMMPNGPMPVPQMMNF--GLPSLAPLVPPPTLLVPYP 528
L+PP P + + +S+ P+ P + + G AP T L P
Sbjct: 2578 SLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLP 2637
Query: 529 VIVPLPVPIP----IPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSP 584
LP+ + + +P SD ++ + ++ KP +
Sbjct: 2638 EGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAE 2697
Query: 585 RDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPG 644
+ SS + SP G S A P ++V + G P PPG PG
Sbjct: 2698 VAAPSTSSSATSSPEGPSP-----ARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPG 2752
Query: 645 VLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAG 704
L +TV L V+ R+ A G + SP G
Sbjct: 2753 RL---------VTVVEEKEL-----------VRRRRQQRGAASTLVPGVSETSASP---G 2789
Query: 705 DPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPA 764
P + +GPE++ G A P P PP P ++ + E
Sbjct: 2790 SPSVRSMSGPESSPPIG------------GPCEAAPSSSLPTPPQQPFIARRHI---ELG 2834
Query: 765 VSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSDPNLN-NPADE----DHAYALR 819
V+ S EN + + A K+ G P N +PAD D A +
Sbjct: 2835 VTGGGS-PENGDGALLAITPPAVKRRRGR---------PPKKNRSPADAGRGVDEAPSST 2884
Query: 820 MLPKTGCVIQPVPKPAEKAAMAPCIISSPMLSAGPEDLEP 859
+ KT PVP P P + P L GP+ L P
Sbjct: 2885 LKGKTNGA-DPVPGPETLIVADP--VLEPQLIPGPQPLGP 2921
Score = 40.4 bits (93), Expect = 0.007
Identities = 61/229 (26%), Positives = 74/229 (32%), Gaps = 64/229 (27%)
Query: 326 PSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPM 385
P V P S P PVP+ +P S + P GPPL +P PP
Sbjct: 1018 PLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPA--------GPPL-IPASRPP- 1067
Query: 386 VMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLG 445
GPV LP PNS LP + P P G
Sbjct: 1068 -----GPVLLP----------------------PLQPNS----GSLPQVLPSPLG----- 1091
Query: 446 PTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQ 505
+LS PP TPT+ L P PP L P PP S P+ VP
Sbjct: 1092 ---------VLSGTSRPP-TPTL-----SLKPTPPAPVRLSPAP-PPGSSSLLKPLTVPP 1135
Query: 506 MMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNG 554
F P A T VP P P P + + ++ P+G
Sbjct: 1136 GYTF--PPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSG 1182
Score = 35.8 bits (81), Expect = 0.18
Identities = 74/288 (25%), Positives = 105/288 (36%), Gaps = 52/288 (18%)
Query: 422 PNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSP-------HIHPPSTPTMPGNPPG 474
P LS +L + P P P ++R ML P + + P P P
Sbjct: 965 PRHRLSRRVLLEVATAPDPPPRPKPVKMKVNR-MLQPVPKQEGRTVVVVNNPRAPLGPVP 1023
Query: 475 LLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGL-PSLAPLVPP--PTLLVPYPVIV 531
+ PPP P +S P P PVPQ++ L S +P PP P P PV++
Sbjct: 1024 VRPPPG----------PELSAQPT-PGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLL 1072
Query: 532 P--------LPVPIPIPIPIPHVSDSKPPNGFSSNGENFIP------NAPGDSAAAG--G 575
P LP +P P+ + + P S P PG S+
Sbjct: 1073 PPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLT 1132
Query: 576 KPSGHSLSPRDSKQGSSKSADS------PPGCSGQALSLAP-TPAEHGRSEVVDLTRRAG 628
P G++ P + S+ +A + P + Q L L+P A EVV + + A
Sbjct: 1133 VPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLAS 1192
Query: 629 SPPGP-PGAGGQLGFPGVLQGPQ-----DGVIDLTVGH-RARLHNVIH 669
P AGG +QG + V L VG R NV+H
Sbjct: 1193 LAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVH 1240
Score = 35.8 bits (81), Expect = 0.18
Identities = 108/496 (21%), Positives = 152/496 (30%), Gaps = 96/496 (19%)
Query: 292 VQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPK 351
V++L N+ LT + APS AG P+ +P ++T +P
Sbjct: 2590 VEILPVSEKNLSLTPS---APSLTLEAGSI----PNGQEQEAPDSAEGTTLTVLPEGEEL 2642
Query: 352 SIPISETPNIPPVSVQPPASIGPPLGVP---PRSPPMVMTNRGPVPLPIFMEQQIMQQIR 408
+ +SE+ + + P A+ PL P R+ + + P P ++ + ++
Sbjct: 2643 PLCVSESNGL---ELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVA 2699
Query: 409 PPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTM 468
P S +S S+P GP P P P R I T
Sbjct: 2700 AP---------STSSSATSSPE----GPSPARP--------PRRRTSADVEIRGQGTGR- 2737
Query: 469 PGNPPGLLPPPPPGAPLP-----------------------SLPFPPVSMMPNGPMPVPQ 505
PG PPG P LP S P VS P P
Sbjct: 2738 PGQPPG----PKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGS-PS 2792
Query: 506 MMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIP-IPIPHVSDSKPPNGFSSNGEN-FI 563
+ + P +P + P P LP P P I H+ G NG+ +
Sbjct: 2793 VRSMSGPESSPPIGGPCEAAPSS---SLPTPPQQPFIARRHIELGVTGGGSPENGDGALL 2849
Query: 564 PNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDL 623
P G+P + SP D+ +G ++ S G+ P P V D
Sbjct: 2850 AITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSST--LKGKTNGADPVPGPETLI-VADP 2906
Query: 624 TRRAGSPPGPPGAGGQ-LGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREP 682
PGP G Q + P L P V R KA P
Sbjct: 2907 VLEPQLIPGPQPLGPQPVHRPNPLLSP-----------------VEKRRRGRPPKARDLP 2949
Query: 683 SAAERRTCG-GCRDGHCSPPAAGDPGPGAPAGP----EAAAACNVIVNGTRGAAAEGAKS 737
+ G G + PP P P P P A N + T + K
Sbjct: 2950 IPGTISSAGDGNSESRTQPPP--HPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKR 3007
Query: 738 AEPPPEQPPPPPPPAP 753
PP P P P P
Sbjct: 3008 GRPPKNPPSPRPSQLP 3023
>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
Length = 411
Score = 81.3 bits (199), Expect = 4e-15
Identities = 99/337 (29%), Positives = 133/337 (39%), Gaps = 58/337 (17%)
Query: 299 SWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISET 358
+W P A++ P A S GPGP + P+ +IP P+P SIP
Sbjct: 76 AWGGPGCRAQKGIP-----AALSPGPGPIPAPIPGPA--------QIPGPLPGSIP-GPI 121
Query: 359 PNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHH 418
P + PA I P+ P + P RGP+P PI I I PF P
Sbjct: 122 PGPAQIPSPIPAPIPGPISGPVQIPGPF---RGPIPGPISGPAPIPGPISGPFSGPNPGP 178
Query: 419 ASNPN-----SPLSNPM-----LPGIGPPPG-------GPRNLGPTSSPMHRPMLSPHIH 461
PN P+S P+ +P GP PG GP N GP P+ P+ P+
Sbjct: 179 IPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGP-NPGPIPGPIPGPISGPNPG 237
Query: 462 PPSTPTMPGNPPGLLPPPPPG---APLPSL-PFPPVSMMPN-------GPMPVPQMMNF- 509
P P + G PGL+P P PG P P + P P + +P GP+ P M
Sbjct: 238 PIPGP-ISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSP 296
Query: 510 -GLPSLAPLVPPPTL----LVPYPVIVPLPVPIPIPI--PIPHVSDSKPPNG-FSSNGEN 561
LP LAP++ P + VP P+ P +P P P+ P SD P F E
Sbjct: 297 GSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPDASDFLPDTQLFPHFTEL 356
Query: 562 FIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSP 598
+P P + ++ S + D G S P
Sbjct: 357 LLPLDPLEGSSVSTMTSQY--QEGDDSMGKKHSGSQP 391
Score = 53.1 bits (126), Expect = 1e-06
Identities = 94/348 (27%), Positives = 127/348 (36%), Gaps = 69/348 (19%)
Query: 304 LTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSI-PISETPNIP 362
L RR P GQ +G G A+ V P+ +A+ P P I P +E P
Sbjct: 20 LARERRLQQQPQRVPGQ-RGRGARAAPLV-PAASASA-----PQRGPSGILPAAE----P 68
Query: 363 PVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNP 422
+ A GP P + GP+P PI QI + P I GP +
Sbjct: 69 TICSLHQAWGGPGCRAQKGIPAALSPGPGPIPAPIPGPAQIPGPL-PGSIPGPIPGPAQI 127
Query: 423 NSPLSNPMLPGIGPPPGGPRNL-GPTSSPMHRPMLSPHIHP-PSTPTMPGNPPGLLPPPP 480
SP+ P +PG P GP + GP P+ P+ P P P + G PG +P P
Sbjct: 128 PSPIPAP-IPG---PISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPN 183
Query: 481 PGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIP 540
PG P+P GP+ P +P P+ VP+P PIP P
Sbjct: 184 PG-PIP------------GPISGP--------------------IPGPISVPIPGPIPGP 210
Query: 541 IPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPG 600
I P + P IP P +G P G P P
Sbjct: 211 ISGPISGPNPGP----------IP-GPIPGPISGPNP-GPIPGPISGPNPGLIPGPIPGP 258
Query: 601 CSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQG 648
SG + P P+ +++ R G PGP + G++ PG L G
Sbjct: 259 ISGPGPIIGPIPSP---AQIPGPGRLQG--PGPILSPGRMRSPGSLPG 301
Score = 47.0 bits (110), Expect = 8e-05
Identities = 65/223 (29%), Positives = 79/223 (35%), Gaps = 27/223 (12%)
Query: 272 PAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTT 331
PA + S + P+ G VQ+ P IP AP P +G GP P
Sbjct: 124 PAQIPSPIPAPIPGPISGP-VQIPGPFRGPIP-GPISGPAPIPGPISGPFSGPNPGPIPG 181
Query: 332 VSPSDTANCSVTKIPTPV----------PKSIPISETPNIPPVSVQPPASIGPPLGVP-- 379
+P IP P+ P S PIS PN P+ P I P P
Sbjct: 182 PNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISG-PNPGPIPGPIPGPISGPNPGPIP 240
Query: 380 -PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPP 438
P S P GP+P PI I+ I P P P LS + G P
Sbjct: 241 GPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLP 300
Query: 439 GGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPP 481
G LGP S P + +P +PG PG LP P P
Sbjct: 301 GLAPILGPGSGPGSGSVPAP---------IPG--PGSLPAPAP 332
Score = 45.4 bits (106), Expect = 2e-04
Identities = 61/225 (27%), Positives = 78/225 (34%), Gaps = 55/225 (24%)
Query: 432 PGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPG-APLPSLPF 490
PG G P L P P+ P+ P +PG PG +P P PG A +PS P
Sbjct: 80 PGCRAQKGIPAALSPGPGPIPAPI-------PGPAQIPGPLPGSIPGPIPGPAQIPS-PI 131
Query: 491 P-PVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDS 549
P P+ +GP+ +P +P P+ P +P P+ P P P PIP P+
Sbjct: 132 PAPIPGPISGPVQIPGPFRGPIPG--PISGPAP--IPGPISGPFSGPNPGPIPGPNPGPI 187
Query: 550 KPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLA 609
P G +P PG G SG P PG
Sbjct: 188 PGPISGPIPGPISVP-IPGPIP---GPISGPISGPN-------------PG--------- 221
Query: 610 PTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVI 654
P P G PGP PG + GP G+I
Sbjct: 222 PIP---------------GPIPGPISGPNPGPIPGPISGPNPGLI 251
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 79.3 bits (194), Expect = 1e-14
Identities = 87/314 (27%), Positives = 110/314 (35%), Gaps = 59/314 (18%)
Query: 281 PPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANC 340
P ++ + VQ P + P ++ P +Q P + SP
Sbjct: 277 PSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRA 336
Query: 341 SVT------KIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVP--PRSPPMVMTNRGP 392
V K P P IP ET + P PP PPL PP GP
Sbjct: 337 VVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPP------GP 390
Query: 393 VPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGI------------------ 434
V + QI P + PP P P + + G+
Sbjct: 391 VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSM 450
Query: 435 ----GPPPGG-PRNLGPTSSPMHRPMLSPHIHPPSTPTMP-GNPPGLLPPPPPGAPLPSL 488
GP G P GP P H P PH++PP+ P P PP PPP P P
Sbjct: 451 MKTEGPSYGALPPAYGP---PAHLPY-HPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGY 506
Query: 489 PFPPVSMMPNGPMPVPQMMNFGLPSLA-PLVPPPTLLVPYPVIVPLPV-------PIPIP 540
P PP + PN P P P++ P+ A P PPP L +P P P P P+P P
Sbjct: 507 PPPPPTYNPNFPPPPPRLP----PTHAVPPHPPPGLGLP-PASYPPPAVPPGGQPPVPPP 561
Query: 541 IPIPHVSDSKPPNG 554
IP P PP G
Sbjct: 562 IPPP----GMPPVG 571
Score = 60.1 bits (144), Expect = 9e-09
Identities = 89/341 (26%), Positives = 108/341 (31%), Gaps = 85/341 (24%)
Query: 321 SQGPGPSASTTVSPSDTAN----CSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPL 376
SQ PS P A K P+P P S + V P
Sbjct: 294 SQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS-----PRQVKRAVVVSPKEENKAA 348
Query: 377 GVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHAS----NPNSPLSNPMLP 432
PP P + T P+P PP R PP A+ P P+ LP
Sbjct: 349 EPPPPKIPKIETTHPPLP-----------PAHPPPDRKPPLAAALGEAEPPGPVDATDLP 397
Query: 433 GIG-PPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFP 491
+ PPP P +P+H+P P +P PP PPPP + + +
Sbjct: 398 KVQIPPPAHP-------APVHQP-----------PPLPHRPP----PPPPSSYMTGMSTT 435
Query: 492 PVSMMPNGPMPVPQMMNFGLPSLAPLVP---PPTLLVPYP-VIVPLPVPIPIP------- 540
M G + MM PS L P PP L +P V P P P P+P
Sbjct: 436 SSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFP 495
Query: 541 ---IPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADS 597
IP P PP ++ N P P A P G L P S
Sbjct: 496 PPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP-----ASYPPPAV 550
Query: 598 PPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGG 638
PPG GQ P P PPG P GG
Sbjct: 551 PPG--GQPPVPPPIP-----------------PPGMPPVGG 572
Score = 30.8 bits (68), Expect = 5.7
Identities = 20/64 (31%), Positives = 24/64 (37%), Gaps = 13/64 (20%)
Query: 700 PPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPP----PPPAPPK 755
PP A G P GP V+ T + A P P PPP PPP PP
Sbjct: 376 PPLAAALGEAEPPGP---------VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPS 426
Query: 756 KLLS 759
++
Sbjct: 427 SYMT 430
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 79.0 bits (193), Expect = 2e-14
Identities = 73/229 (31%), Positives = 84/229 (36%), Gaps = 63/229 (27%)
Query: 308 RRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQ 367
R + P A G + PGP+ P P P +TP PP+
Sbjct: 202 RGRGRFPGAVPGGDRFPGPAG-----------------PGGPPPPFPAGQTPPRPPLG-- 242
Query: 368 PPASIGPPLGVPPRS---PPMV-MTNRGPVPLP--IFMEQQIMQQIRPPFIRGPPHHASN 421
PP GPP PP PP+ NRG P P +F Q Q P GPP
Sbjct: 243 PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP----- 297
Query: 422 PNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPP 481
P +PG GPPPG P P P PP P PPG L PP
Sbjct: 298 -------PPVPGYGPPPGPPP---PQQGP-----------PPPPGPFPPRPPGPLGPPLT 336
Query: 482 GAPLPSLPFPPVSMMPNGPMPVPQM--------MNFGLPSLAPLVPPPT 522
AP P LP PP P P P P + N G+P+ PPPT
Sbjct: 337 LAPPPHLPGPP----PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPT 381
Score = 57.0 bits (136), Expect = 7e-08
Identities = 72/238 (30%), Positives = 81/238 (34%), Gaps = 63/238 (26%)
Query: 408 RPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPT 467
R F +G P + PG P G P P PP P
Sbjct: 194 RAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP------------PPFPAGQTPPRPPL 241
Query: 468 MPGNPPGLLPPPPPGAPLPSLPFPPVSMMPN-GPMPVPQMM----NFGLPSLAPLVPPPT 522
P PPG PPPPG LP PP++ PN G P P ++ FG P L PL P P
Sbjct: 242 GPPGPPGPPGPPPPGQVLP----PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP- 296
Query: 523 LLVPYPVIVPLPVP--IPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGH 580
P PVP P P P P PP G F P PG G P
Sbjct: 297 ---------PPPVPGYGPPPGPPPPQQGPPPPPG------PFPPRPPGPL----GPPL-- 335
Query: 581 SLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPP----GPP 634
+L+P G PPG AP PA H +G P GPP
Sbjct: 336 TLAPPPHLPG------PPPG--------APPPAPHVNPAFFPPPTNSGMPTSDSRGPP 379
Score = 47.8 bits (112), Expect = 5e-05
Identities = 68/243 (27%), Positives = 72/243 (29%), Gaps = 84/243 (34%)
Query: 414 GPPHHASN---PNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPG 470
GPP +S P PG PGG R GP P PP P P
Sbjct: 187 GPPGGSSRAAFPQGGRGRGRFPGA--VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPP 244
Query: 471 NPPGLLPPPPPGAPLPSLPFPPVSMMPN-GPMPVPQMMNFGLPSLAPLVPPPTLLVPYPV 529
PPG PPPPG LP PP++ PN G P PPP L P
Sbjct: 245 GPPGPPGPPPPGQVLP----PPLAGPPNRGDRP----------------PPPVLFPGQPF 284
Query: 530 IVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQ 589
P P+P P P P V PP PG G P
Sbjct: 285 GQPPLGPLP-PGPPPPVPGYGPP--------------PGPPPPQQGPPP----------- 318
Query: 590 GSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGP 649
PPG P P PPGP G L P L GP
Sbjct: 319 --------PPG---------PFPPR---------------PPGPLGPPLTLAPPPHLPGP 346
Query: 650 QDG 652
G
Sbjct: 347 PPG 349
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/83 (30%), Positives = 28/83 (33%), Gaps = 22/83 (26%)
Query: 701 PAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKS-----------AEPP----PEQP 745
P G PGP P GP V+ G G + +PP P P
Sbjct: 239 PPLGPPGPPGPPGPPPPG--QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296
Query: 746 PPP-----PPPAPPKKLLSPEEP 763
PPP PPP PP P P
Sbjct: 297 PPPVPGYGPPPGPPPPQQGPPPP 319
Score = 32.3 bits (72), Expect = 2.0
Identities = 13/23 (56%), Positives = 15/23 (65%), Gaps = 1/23 (4%)
Query: 734 GAKSAEPPPEQPPPPPP-PAPPK 755
G PPP+Q PPPPP P PP+
Sbjct: 304 GPPPGPPPPQQGPPPPPGPFPPR 326
Score = 31.2 bits (69), Expect = 4.4
Identities = 19/61 (31%), Positives = 21/61 (34%), Gaps = 1/61 (1%)
Query: 706 PGPGAPAGPEAA-AACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPA 764
PGP P GP A G PPP Q PPP PP + P P
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277
Query: 765 V 765
+
Sbjct: 278 L 278
Score = 30.8 bits (68), Expect = 5.7
Identities = 19/67 (28%), Positives = 22/67 (32%), Gaps = 20/67 (29%)
Query: 694 RDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAP 753
+ G PP P P P GP A PPP P PPP P
Sbjct: 313 QQGPPPPPGPFPPRPPGPLGPPLTLA--------------------PPPHLPGPPPGAPP 352
Query: 754 PKKLLSP 760
P ++P
Sbjct: 353 PAPHVNP 359
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 78.6 bits (192), Expect = 2e-14
Identities = 107/377 (28%), Positives = 143/377 (37%), Gaps = 73/377 (19%)
Query: 289 GTGVQLLTPDSWNIPLTDAR-RKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPT 347
GTGV P +PL P+P+ PG SAS S D ++ +P
Sbjct: 180 GTGV----PVEGTLPLVTTNFSPLPAPICPPA----PG-SASVPHSVPDAFQVPLS-VPA 229
Query: 348 PVPKS--IPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQ 405
PVP S +P+ ++P S PP + P L P S P ++++
Sbjct: 230 PVPHSGLVPVQVATSVPAPS--PPLAPVPALAPAPPSVPTLISD---------------- 271
Query: 406 QIRPPFIRGPPHHASNPNSPLSNPMLP-GIGPPPGGPRNLG-PTSSPMHRPMLSPHIHPP 463
SNP S ++ ++P PP GP L P +P+ P+ +P +
Sbjct: 272 --------------SNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALI 317
Query: 464 STPTMPGNPPGLLPPPPPG--APLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPP 521
P P P +L P P AP+P+ P P+ PMP P + G PS L+P
Sbjct: 318 QAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSS-GPPSTPTLIPA- 375
Query: 522 TLLVPYPVIVPLPVPI--PIPIPIP-----HVSDSKP-PNGFSSNGENFIPNAPGDSAAA 573
P PV P P PI P P P+P + S P P FS + F P A A
Sbjct: 376 --FAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCF----PAAQAPA 429
Query: 574 GGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGP 633
K S P S PP GQ LS+A P G S + L P
Sbjct: 430 MQKVP-LSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTL-------PVL 481
Query: 634 PGAGGQLGFPGVLQGPQ 650
P PGVL P+
Sbjct: 482 PSYLQDRCLPGVLASPE 498
Score = 44.7 bits (104), Expect = 4e-04
Identities = 75/350 (21%), Positives = 116/350 (33%), Gaps = 48/350 (13%)
Query: 310 KAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIP------- 362
+AP P + P P+ P+ T + P+P P S P+ P
Sbjct: 318 QAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFA 377
Query: 363 --PVSVQPPASIGPPLGVP-PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRG----- 414
PV PA I P P P + P + P+P + + + P ++
Sbjct: 378 PTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSF 437
Query: 415 PPHHASNPNSPLSNPMLPGIGPPPGG---PRNLGPTSSPMHRPMLSPHIHPPSTPTMPGN 471
P P+ PL P G P P LG SS + P+L ++ P + +
Sbjct: 438 QPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLG-VSSTLTLPVLPSYLQDRCLPGVLAS 496
Query: 472 PP--------GLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTL 523
P + P + L SL + Q G+P PL +L
Sbjct: 497 PELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVP--GPLA-DTSL 553
Query: 524 LVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLS 583
+ ++P P P+ +P P S + P +G G S + S
Sbjct: 554 VTASAKVLPTPQPL---LPAPSGSSAPPHPAKMPSGTE--QQTEGTSV---------TFS 599
Query: 584 PRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGP 633
P S + SPP CS L L + + + L + +PP P
Sbjct: 600 PLKSPPQLEREMASPPECSEMPLDL----SSKSNRQKLPLPNQRKTPPMP 645
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 78.2 bits (191), Expect = 3e-14
Identities = 98/369 (26%), Positives = 126/369 (34%), Gaps = 77/369 (20%)
Query: 410 PFIRGPPHHASNPNSP-LSNPMLP-GIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPT 467
P IRGPP + +P P L+ P P G+ PG P G +P + + S + P
Sbjct: 763 PGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAP-GKIVTSEGSSMLTVPG 821
Query: 468 MPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPY 527
PG P + PP PPGAP P+ GP +P L P PP P
Sbjct: 822 PPGPPGAMGPPGPPGAPGPA-----------GPAGLPGHQEV-LNLQGPPGPPGPRGPPG 869
Query: 528 PVIVPLPVPIPIP---IPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSP 584
P I P P P +P P PP F SN E F+ PG G K P
Sbjct: 870 PSIPGPPGPRGPPGEGLPGP----PGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGP 925
Query: 585 RDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPG 644
R + S G S L+L P G P GP G G G PG
Sbjct: 926 RGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPG-------------PQGPKGDKGDPGVPG 972
Query: 645 VL---QGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPP 701
L GP +G G + S P
Sbjct: 973 ALGIPSGPSEG--------------------------------------GSSSTMYVSGP 994
Query: 702 AAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPE 761
G PGP P G +++ + + ++ +S + PP PP P P ++ E
Sbjct: 995 -PGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGE 1053
Query: 762 EPAVSELES 770
SEL S
Sbjct: 1054 TFDYSELAS 1062
Score = 54.7 bits (130), Expect = 4e-07
Identities = 111/467 (23%), Positives = 145/467 (31%), Gaps = 103/467 (22%)
Query: 397 IFMEQQIMQQIRPPFIRGPPHHASNPNSPLSN-----PMLPGIGPPPGGPRNLGPTSSP- 450
+F+ +++M + +RG P + SP P PGI P G P GP
Sbjct: 550 MFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKG 609
Query: 451 ------MHRPMLSPHIHPPSTPTMPGNPPGLL------------PPPPPGAPLPSLPF-- 490
M PM P P PPG P PPG P P
Sbjct: 610 SVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGS 669
Query: 491 --PPVSMMPNGPMPVPQMMN-FGLPSL----APLVPP----------PTLLVPYPVIVPL 533
P P GP+ + + GLP + P+ PP P L P + L
Sbjct: 670 SGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGL 729
Query: 534 PVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAG--GKPSGHSLSPRDSKQGS 591
P + P + + P GE + PG G G P L+ QG
Sbjct: 730 PGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGL 789
Query: 592 SKSADSP-----PGCSGQAL-----SLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLG 641
+ P PG G+ + S+ P G + PPGPPGA G G
Sbjct: 790 PGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM-------GPPGPPGAPGPAG 842
Query: 642 FPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPP 701
P L G Q+ V++L + P G PP
Sbjct: 843 -PAGLPGHQE-VLNL----------------------QGPPGP----------PGPRGPP 868
Query: 702 AAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPE 761
PGP P GP + G G ++E PP PP P PK P
Sbjct: 869 GPSIPGPPGPRGPPGEG-----LPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPP 923
Query: 762 EPAVSELESVKENNCASNCHLDGEAAKKLMGEEALAG--GDKSDPNL 806
P + E S G + G G GDK DP +
Sbjct: 924 GPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGV 970
Score = 53.1 bits (126), Expect = 1e-06
Identities = 74/278 (26%), Positives = 93/278 (33%), Gaps = 88/278 (31%)
Query: 369 PASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSN 428
P GPP + P PP GP LP Q+++ ++GPP
Sbjct: 820 PGPPGPPGAMGPPGPPGAPGPAGPAGLP--GHQEVLN------LQGPP------------ 859
Query: 429 PMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSL 488
GPP GPR P P++PG PPG P PPG LP
Sbjct: 860 ------GPP--GPRG-------------------PPGPSIPG-PPG--PRGPPGEGLPGP 889
Query: 489 PFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSD 548
P PP S + N S L PP P P D
Sbjct: 890 PGPPGSFLSN--------------SETFLSGPP----------------GPPGPPGPKGD 919
Query: 549 SKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQG--SSKSADSPPGCSGQAL 606
PP GE +P + +G G +L G K PG G AL
Sbjct: 920 QGPPGPRGHQGEQGLPG----FSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPG-AL 974
Query: 607 SLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPG 644
+ P+E G S + ++ G PPGPPG G + G
Sbjct: 975 GIPSGPSEGGSSSTMYVSGPPG-PPGPPGPPGSISSSG 1011
Score = 39.3 bits (90), Expect = 0.016
Identities = 73/289 (25%), Positives = 95/289 (32%), Gaps = 68/289 (23%)
Query: 477 PPPPPGAP----LPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVP 532
PP PPGA L SL + +S M ++ GLP P PP Y ++
Sbjct: 1110 PPGPPGASGDGSLLSLDYAELSSRILSYMS-SSGISIGLPG--PPGPPGLPGTSYEELLS 1166
Query: 533 L-----------PVPIPIPIPIP-----HVSDSKPPNGFSSNGENFIPNAPGDSAAAGGK 576
L P P P IP +S + + G +FIP PG G
Sbjct: 1167 LLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPG-- 1224
Query: 577 PSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVV------DLTRRAGSP 630
PR PPG SG + A ++ RSE++ D+ P
Sbjct: 1225 -------PR-----------GPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGP 1266
Query: 631 PGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTC 690
PGPPG G G ++ H + H + + +
Sbjct: 1267 PGPPGPQGPPG--------DSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGA 1318
Query: 691 GGCRDGHCSPPAAGDPGP-GAPAGPEAAAACNVIVNGTRGAAAEGAKSA 738
G G AAGD GP G GP G GAAAEG A
Sbjct: 1319 GSLGAGGAFGEAAGDRGPYGTDIGP----------GGGYGAAAEGGMYA 1357
Score = 38.5 bits (88), Expect = 0.027
Identities = 104/472 (22%), Positives = 137/472 (29%), Gaps = 132/472 (27%)
Query: 314 PVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIG 373
P G PGPS P + P P + SET PP G
Sbjct: 858 PPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSET-----FLSGPPGPPG 912
Query: 374 PPLGVPPRSPPMVMTNRGPVPLPIFMEQQI----MQQIRPPFIRGPPHHASNPNSPLSNP 429
PP + PP ++G LP F + PP GPP P +P
Sbjct: 913 PPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPP---GPP-GPQGPKGDKGDP 968
Query: 430 MLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLP 489
+PG P GP G +SS M+ PPG PP PPG
Sbjct: 969 GVPGALGIPSGPSE-GGSSSTMY----------------VSGPPG--PPGPPG------- 1002
Query: 490 FPPVSMMPNGPMPVPQ-----MMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIP 544
PP S+ +G + Q M + + S V P P P P P+
Sbjct: 1003 -PPGSISSSG-QEIQQYISEYMQSDSIRSYLSGVQGP------------PGPPGPPGPVT 1048
Query: 545 HVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSS------------ 592
++ GE F + + + SG+ +S S S
Sbjct: 1049 TIT-----------GETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVR 1097
Query: 593 ----------KSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGF 642
+ PPG SG L+ AE S ++ +G G PG G G
Sbjct: 1098 QYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELS-SRILSYMSSSGISIGLPGPPGPPGL 1156
Query: 643 PGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPA 702
PG + ++ L G R
Sbjct: 1157 PGT---SYEELLSLLRGSEFR-------------------------------------GI 1176
Query: 703 AGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPP 754
G PGP P G ++ V S P P PP PP P P
Sbjct: 1177 VGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGP 1228
Score = 32.7 bits (73), Expect = 1.5
Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 544 PHVSDSKPPNGFSSNGENFIPNAPGDSAAA--GGKPSGHSLSPRDSK--------QGSSK 593
P+ +D P G+ + E + G A G + L+ R S+ QG +
Sbjct: 1336 PYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAY 1395
Query: 594 SADSPPGCSGQ----ALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPG 644
+ PPG G +S + + ++++D + G+ GPPG G++G PG
Sbjct: 1396 TVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPG 1450
Score = 32.0 bits (71), Expect = 2.6
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 24/115 (20%)
Query: 370 ASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNP 429
+S G +G+P PP GP LP ++++ +R RG + P
Sbjct: 1139 SSSGISIGLP--GPP------GPPGLPGTSYEELLSLLRGSEFRG-----------IVGP 1179
Query: 430 MLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAP 484
PG PPG P N+ + S LS ++H +PG P PP P G P
Sbjct: 1180 --PGPPGPPGIPGNVWSSISVED---LSSYLHTAGLSFIPGPPGPPGPPGPRGPP 1229
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 78.2 bits (191), Expect = 3e-14
Identities = 104/386 (26%), Positives = 152/386 (39%), Gaps = 65/386 (16%)
Query: 270 NLPAGLCSTLHPPMENKA------EGTGVQLLTPDSWNIPLTDARRKAPSP-VATAGQSQ 322
++PA + + PP ++ A +G G+ PDS P AP+P + A +
Sbjct: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASP-------APAPQIPAAAPLK 769
Query: 323 GPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLG--VPP 380
GPGPS+S ++ P +P+P P + P S P+ P +PP+ PPL PP
Sbjct: 770 GPGPSSSPSL-PHQAPLGDSPHLPSPHP-TRPPSRPPSRPQSVSRPPSE--PPLHPCPPP 825
Query: 381 RSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGG 440
++PP +P ++ Q+ G P ASNP P PG PP
Sbjct: 826 QAPP-------TLPGIFVIQNQL----------GVPPPASNP-----APTAPGPPQPP-- 861
Query: 441 PRNLGPTSSPMHRPM-LSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPS---LPFPPVSMM 496
L P S P P+ +PH+ P ST + + P AP PS L FPP
Sbjct: 862 ---LRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLP--APTPSDFQLQFPPSQGP 916
Query: 497 PNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFS 556
P P P + P+ P PP T + V P P +P P + P
Sbjct: 917 HKSPTPPPTLHLVPEPAAPPPPPPRTFQM---VTTPFPA-LPQPKALLERFHQVPSGIIL 972
Query: 557 SNGENFIPNAPGDSAAAG--GKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAP--TP 612
N P AP S + G P+ L + G+ + P + A + P P
Sbjct: 973 QNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLP 1032
Query: 613 AEH----GRSEVVDLTRRAGSPPGPP 634
AE+ +++ + A S PG P
Sbjct: 1033 AENKAFASNLPTLNVAKAASSGPGKP 1058
Score = 65.9 bits (159), Expect = 2e-10
Identities = 153/641 (23%), Positives = 214/641 (33%), Gaps = 181/641 (28%)
Query: 292 VQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTP--- 348
+Q+ P + +P++ A P T Q GP+A+T + +V + TP
Sbjct: 547 IQVGQPALFQMPVSLAAGSLP----TQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGL 602
Query: 349 VPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIR 408
V + P + T PV PA P++PP V T PLP+ ++Q QQ
Sbjct: 603 VQPATPAAATGEAAPVLTVQPA---------PQAPPAVST-----PLPLGLQQPQAQQ-- 646
Query: 409 PPFIRGPPHHASNPNSPLSNPMLPGIGPPP-----GGPRNLGPTS----------SPMHR 453
PP + P A+ P + PG+ P G P + PT+ P R
Sbjct: 647 PP--QAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQER 704
Query: 454 PML-----SPHIHPPSTPTMPGNPPGLLPPP---------------------------PP 481
PH+ P++ + PP P P P
Sbjct: 705 SQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPA 764
Query: 482 GAPL--------------------PSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVP-- 519
APL P LP P + P+ P PQ ++ PS PL P
Sbjct: 765 AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVS-RPPSEPPLHPCP 823
Query: 520 ----PPTLLVPYPVIVPLPVPIPIPIPIPHV---------SDSKPPNGFSSNGENFIPNA 566
PPTL + + L VP P P P S+PP G + P++
Sbjct: 824 PPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSS 883
Query: 567 PGDSAAAGGKPSGHSLSPRDS--------KQGSSKSADSPPGCSGQALSLAPTPAEHGRS 618
+ A+ + S +P S QG KS PP L L P PA
Sbjct: 884 TSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPP-----TLHLVPEPA----- 933
Query: 619 EVVDLTRRAGSPPGPPGAGGQL---GFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAH 675
+PP PP Q+ FP + PQ + R H V
Sbjct: 934 ----------APPPPPPRTFQMVTTPFPAL---PQPKAL------LERFHQV-------- 966
Query: 676 VKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGA 735
PS + G PAA P GP + A +V+V+ G A G
Sbjct: 967 ------PSGIILQNKAG------GAPAA--PQTSTSLGPLTSPAASVLVS---GQAPSGT 1009
Query: 736 KSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEA 795
+A P P P L + + S L ++ AS+ G + E+
Sbjct: 1010 PTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASS----GPGKPSGLQYES 1065
Query: 796 LAGGDKSDPNLNNPADEDHAYALRMLPK-TGCVIQPVPKPA 835
G K P L P+ E A L L K G V+ P K A
Sbjct: 1066 KLSGLKKPPTL-QPSKE--ACFLEHLHKHQGSVLHPDYKTA 1103
Score = 40.4 bits (93), Expect = 0.007
Identities = 102/453 (22%), Positives = 150/453 (33%), Gaps = 84/453 (18%)
Query: 369 PASIGPPLGVPPRSP-PMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLS 427
P ++ P LG P P P V+ +R P P+ + + + P + P + + L+
Sbjct: 324 PLAVAPGLGSSPLVPAPNVILHRTPTPI----QPKPAGVLPPKLYQLTPKPFAPAGATLT 379
Query: 428 NPMLPGIGPP-PGGPRNL----------GPTSSPMHRPMLSPHI--HPPSTPTMPGNPPG 474
PG P P P+NL S P L ++ PP+T T G
Sbjct: 380 IQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTT------G 433
Query: 475 LLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMM----NFGLPSLAPLVPPPTLLVPYPVI 530
PP PPGA + ++ + +P M+ F LP AP V P L P
Sbjct: 434 AAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPG-APAVQLPQQLSALPAN 492
Query: 531 VPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAA-GGKPSGHSLSPRDSKQ 589
V + + PH N +N P + G A G S H LS +
Sbjct: 493 VGGQI---LAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQV 549
Query: 590 GSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGP 649
G P + +L PA G + L PP A L P L P
Sbjct: 550 GQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQ----GVTLPPSAVAMLNTPDGLVQP 605
Query: 650 Q-------DGVIDLTVGHRARLHNVIHRALHAHV---KAEREPSAAERRTCGGCRDGHCS 699
+ LTV + + L + +A++ P A + +
Sbjct: 606 ATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQA--------AA 657
Query: 700 PPAA--GDPGPGAPAGPE--------AAAACNVIVNGT-----------RGAAAEGAK-- 736
PP A P PG + PE +A ++ + + +AEG
Sbjct: 658 PPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLS 717
Query: 737 ------SAEPPPEQPPPPPPPAPPKKLLSPEEP 763
+ PPP Q P P P L P+ P
Sbjct: 718 VPASVIVSAPPPAQDPAPATPVAKGAGLGPQAP 750
Score = 35.0 bits (79), Expect = 0.30
Identities = 47/219 (21%), Positives = 77/219 (35%), Gaps = 29/219 (13%)
Query: 306 DARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIP--P 363
D + P P AT ++ P P P+ N +V P P+ P+ P+ P P
Sbjct: 1328 DPVHQPPPPPATLKVAEPP-PRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLP 1386
Query: 364 VSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQ----------QIMQQIRPPFIR 413
+ ++G P G P +P P PLP +++ + ++ ++
Sbjct: 1387 LRKTYRENVGGP-GAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLK 1445
Query: 414 G-PPHHASNPNSPLSNPMLPGIGPPPGGPR-----NLGPTSSPMHRPM---LSPHIHPPS 464
G PP A++ +P G PP R ++ S P L+ H+
Sbjct: 1446 GPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAI 1505
Query: 465 TPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPV 503
+ L P P PS P + P P P+
Sbjct: 1506 DSILN------LQQAPGRTPAPSYPHAASAGTPASPPPL 1538
Score = 35.0 bits (79), Expect = 0.30
Identities = 15/32 (46%), Positives = 16/32 (50%)
Query: 736 KSAEPPPEQPPPPPPPAPPKKLLSPEEPAVSE 767
K AEPPP PPPPPP + PA E
Sbjct: 1341 KVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE 1372
Score = 30.0 bits (66), Expect = 9.8
Identities = 38/143 (26%), Positives = 48/143 (33%), Gaps = 12/143 (8%)
Query: 630 PPGPPGAGGQLGFPGVLQGPQDGVIDL----TVGHRARLHNVIHRALHAHVKAEREPSAA 685
PP PP GQ+ G + P + T H RL + + +V P A
Sbjct: 1349 PPPPPPPTGQMN--GTVDHPPPAAPERKPLGTAPHCPRLP--LRKTYRENVGG---PGAP 1401
Query: 686 ERRTCGGCRDGHCSP-PAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQ 744
E G R G +P PA D AA + +G E A SA
Sbjct: 1402 EGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGD 1461
Query: 745 PPPPPPPAPPKKLLSPEEPAVSE 767
P P PP K E P V +
Sbjct: 1462 PDWEAPGLPPAKRRKSESPDVDQ 1484
>gi|23510333 pygopus homolog 2 [Homo sapiens]
Length = 406
Score = 77.8 bits (190), Expect = 4e-14
Identities = 105/358 (29%), Positives = 131/358 (36%), Gaps = 76/358 (21%)
Query: 281 PPMENKAEGTGVQLLTPDSWNIPLTDARR-------KAPSPVATAGQSQGPGPSASTTVS 333
PP +K EG G P P T ++ K+P +QGP S T +
Sbjct: 6 PPPPDKLEGGGGPAPPPAP---PSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFA 62
Query: 334 PSDTANCSVTKIPTPVPKSI----PISETPNIPPVSVQPPASIGPPL---------GVPP 380
P PTP+ + P + P V V P +G P+ G+
Sbjct: 63 PP----------PTPMVDHLVASNPFEDDFGAPKVGVAAPPFLGSPVPFGGFRVQGGMAG 112
Query: 381 RSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGG 440
+ PP T G P P+ + PPF PP NP P N G G PP
Sbjct: 113 QVPPGYSTGGGGGPQPLRRQP-------PPF---PP----NPMGPAFNMPPQGPGYPP-- 156
Query: 441 PRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLP--PPPPGAPLPSLPFPPVSM--- 495
P N+ S P ++P L + PPS MPG G P P G P P P S+
Sbjct: 157 PGNMNFPSQPFNQP-LGQNFSPPSGQMMPGPVGGFGPMISPTMGQP-PRAELGPPSLSQR 214
Query: 496 -----MPNGPMPVPQMMNFGLPSLAPLVPP---PTLLVPYP----VIVPLPVPIPIPIP- 542
P GP P+ Q GLPSL P P P P P PL P P
Sbjct: 215 FAQPGAPFGPSPL-QRPGQGLPSLPPNTSPFPGPDPGFPGPGGEDGGKPLNPPASTAFPQ 273
Query: 543 IPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPG 600
PH P + N +F PN+ G GG P +SL+P K G PPG
Sbjct: 274 EPH--SGSPAAAVNGNQPSFPPNSSG---RGGGTPDANSLAP-PGKAGGGSGPQPPPG 325
Score = 30.0 bits (66), Expect = 9.8
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 5/74 (6%)
Query: 691 GGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPP-PP 749
G + G +PP G P P + A V G + G +P QPPP PP
Sbjct: 83 GAPKVGVAAPPFLGSPVPFGGFRVQGGMAGQV----PPGYSTGGGGGPQPLRRQPPPFPP 138
Query: 750 PPAPPKKLLSPEEP 763
P P + P+ P
Sbjct: 139 NPMGPAFNMPPQGP 152
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 76.3 bits (186), Expect = 1e-13
Identities = 108/407 (26%), Positives = 130/407 (31%), Gaps = 71/407 (17%)
Query: 368 PPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLS 427
PP GPP G P PP +G P R + GPP NP P
Sbjct: 838 PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARG--LPGPPGSNGNPGPPGP 895
Query: 428 NPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPS 487
+ PG PPG N G SP P PG PPGAP
Sbjct: 896 SGS-PGKDGPPGPAGNTGAPGSPGVSG-------PKGDAGQPGEKGSPGAQGPPGAP--- 944
Query: 488 LPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVS 547
GP+ + G+ L PP + P P P P + S
Sbjct: 945 -----------GPLGIA-----GITGARGLAGPPGM--------PGPRGSPGPQGVKGES 980
Query: 548 DSKPPNGFSSN----GENFIPNAPGDSAAAG--GKPSGHSLSPRDSKQGS--------SK 593
NG S G +P G + G G P L RD G S
Sbjct: 981 GKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSP 1040
Query: 594 SADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGV 653
A PG G + P R E P G PG G G PG QGP+
Sbjct: 1041 GAPGAPGHPGPPGPVGPAGKSGDRGE-----SGPAGPAGAPGPAGSRGAPGP-QGPRGDK 1094
Query: 654 IDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAG 713
+ G R HR + A P A ++ G SP AG GP P+G
Sbjct: 1095 GE--TGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG------SPGPAGPRGPVGPSG 1146
Query: 714 PEAAAACN-----VIVNGTRGAAAE-GAKSAEPPPEQPPPPPPPAPP 754
P + + G RG E G++ + P QP PP PP P
Sbjct: 1147 PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAP 1193
Score = 63.5 bits (153), Expect = 8e-10
Identities = 97/362 (26%), Positives = 118/362 (32%), Gaps = 58/362 (16%)
Query: 414 GPPHHASNPNSPLSN--PMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGN 471
GPP A P P LPGI P G P G T P P P G
Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF-------PGAPGQNGE 820
Query: 472 PPGLLPPPPPGAP----LPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPY 527
P G PG P + PP P GP P PQ + S
Sbjct: 821 PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP-PGPQGVKGERGSPGG----------- 868
Query: 528 PVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGK----PSGHSLS 583
P P +P P + PP S G++ P G++ A G P G +
Sbjct: 869 PGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQ 928
Query: 584 PRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFP 643
P + S A PPG G L +A G + + GSP GP G G+ G P
Sbjct: 929 PGEK---GSPGAQGPPGAPGP-LGIAGITGARGLAGPPGMPGPRGSP-GPQGVKGESGKP 983
Query: 644 GVL--------QGPQDGVIDL--TVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGC 693
G GPQ G+ L T G R N L + P R G
Sbjct: 984 GANGLSGERGPPGPQ-GLPGLAGTAGEPGRDGNPGSDGLPGR---DGSPGGKGDRGENGS 1039
Query: 694 RDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAP 753
+P A G PGP P GP +G RG + + P P P P
Sbjct: 1040 PG---APGAPGHPGPPGPVGPAGK-------SGDRGESGPAGPAGAPGPAGSRGAPGPQG 1089
Query: 754 PK 755
P+
Sbjct: 1090 PR 1091
Score = 58.9 bits (141), Expect = 2e-08
Identities = 94/359 (26%), Positives = 108/359 (30%), Gaps = 53/359 (14%)
Query: 413 RGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNP 472
RG P P P N PG GGP GP P P P PT PG
Sbjct: 572 RGQPGVMGFPG-PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQ--GPPGPTGPGGD 628
Query: 473 PGLLPPPPPGA--PLPSLPFPP-VSMMPNGPMPVPQMMNFGLP-----SLAPLVPPPTLL 524
G PP P LP PP + P P P G P + AP P L
Sbjct: 629 KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688
Query: 525 VPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGK-PSGHSLS 583
P + P P P + PP + G + PG+ G P G
Sbjct: 689 AGAPGLRGGAGP---PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745
Query: 584 PRDSKQGSSKSADSPPGCSGQALSLAPT--PAEHGRSEVVDLTRRAGSPPGPPGAGGQLG 641
P D P G +G P P + G L AG P G PG G+ G
Sbjct: 746 PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAG-PRGSPGERGETG 804
Query: 642 FPGVLQGP----QDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGH 697
PG P Q+G EP R G +
Sbjct: 805 PPGPAGFPGAPGQNG----------------------------EPGGKGERGAPGEKGEG 836
Query: 698 CSPPAAGDPG---PGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAP 753
P AG PG P P GP+ G A GA+ PP P PP P
Sbjct: 837 GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGP 895
Score = 57.4 bits (137), Expect = 6e-08
Identities = 117/468 (25%), Positives = 147/468 (31%), Gaps = 87/468 (18%)
Query: 336 DTANCSVTKIPTPVPKSIPISET----PNIPPVSVQPPASIGP--PLGVPPRSPPMVMTN 389
D C ++ P P+ IP E P P +PP GP P G P PP +
Sbjct: 63 DDIICDDQELDCPNPE-IPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDP--GPPGIPGR 119
Query: 390 RGPVPLPIFMEQQIMQQIRPPFIRGPPHHASN-PNSPLS-NPMLPG--------IGPPPG 439
G +P Q P GPP + P P + +P +G G
Sbjct: 120 NGDPGIP--------GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAG 171
Query: 440 GPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNP--PGLLPPP-PPGAPLPS-LPFPPVSM 495
P GP P PP T PG+P PG PP PG PS P PP ++
Sbjct: 172 YPGPAGPPGPP----------GPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI 221
Query: 496 MPNGPMPVP-QMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNG 554
P+GP + G P L PP I P IP K G
Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGPPG--------------IKGPAGIPGFPGMKGHRG 267
Query: 555 FSSN----GENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAP 610
F GE P G++ G + + PR + + PG +G +
Sbjct: 268 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAP--GERGRPGLPGAAGARGN--- 322
Query: 611 TPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHR 670
D R + PGPPG G GFPG + + G
Sbjct: 323 -----------DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEP 371
Query: 671 ALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGA 730
H A+ P G + G PG GP A N G RG
Sbjct: 372 GPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANG-APGLRGG 430
Query: 731 AAEGAKS---AEPPPEQ-------PPPPPPPAPPKKLLSPEEPAVSEL 768
A E K+ EP P P P K SP EP + L
Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL 478
Score = 53.1 bits (126), Expect = 1e-06
Identities = 100/375 (26%), Positives = 125/375 (33%), Gaps = 64/375 (17%)
Query: 414 GPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIH-----PPSTPTM 468
GPP A P SP + G P G P G +P R P H PP P +
Sbjct: 336 GPPGTAGFPGSPGAK----GEVGPAGSP---GSNGAPGQRGEPGPQGHAGAQGPPGPPGI 388
Query: 469 PGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYP 528
G+P G P G +P P M GP P P N G P L P
Sbjct: 389 NGSPGGKGEMGPAG-----IPGAPGLMGARGP-PGPAGAN-GAPGLRGGAGEPGKNGAKG 441
Query: 529 VIVPLPVPIPIPIPIPHVSDSKPPNGFSSN----GENFIPNAPGDSAAAGGK-PSGHSLS 583
P P IP V +K +G + G N +P A G+ A G + P+G +
Sbjct: 442 --EPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499
Query: 584 PRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSP--------PGPPG 635
P + + A P G G A P G + GSP PGPPG
Sbjct: 500 PGEKGPAGERGAPGPAGPRG----AAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555
Query: 636 AGGQLGFPGVLQGP-----QDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSA-AERRT 689
+ G+ G PG GP Q GV+ G + + P ER
Sbjct: 556 SQGESGRPGP-PGPSGPRGQPGVMGFP-GPKGN---------------DGAPGKNGERGG 598
Query: 690 CGGCRDGHCSPPAA-GDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPP 748
GG G PP G+ GP P GP +G PP + P
Sbjct: 599 PGG--PGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP 656
Query: 749 PPPAPPKKLLSPEEP 763
P P +P P
Sbjct: 657 GEPGPKGDAGAPGAP 671
Score = 37.0 bits (84), Expect = 0.080
Identities = 30/87 (34%), Positives = 33/87 (37%), Gaps = 13/87 (14%)
Query: 413 RGPPHHASNPNSPLSNPMLPGIGPP-PGGPRNLGPTSSPMHRPMLSPHIHPPSTPT---- 467
RG P + P SP IG P P GPR S P + S H P P
Sbjct: 1109 RGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGN 1168
Query: 468 --------MPGNPPGLLPPPPPGAPLP 486
PG+P PP PPGAP P
Sbjct: 1169 RGERGSEGSPGHPGQPGPPGPPGAPGP 1195
Score = 35.4 bits (80), Expect = 0.23
Identities = 93/365 (25%), Positives = 105/365 (28%), Gaps = 77/365 (21%)
Query: 309 RKAPSPVATAGQSQGPGPSASTTVS--PSDTANCSVTKIP-TPVPKSIPISETPNIPPVS 365
R P P + G PGPS S P N P PK P +
Sbjct: 878 RGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937
Query: 366 VQPPASIGP--------------PLGVP-PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPP 410
PP + GP P G+P PR P +G P + + PP
Sbjct: 938 QGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKP--GANGLSGERGPP 995
Query: 411 FIRGPPHHASNPNSP--LSNP---MLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPST 465
+G P A P NP LPG PGG + G SP P H PP
Sbjct: 996 GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSP-GAPGAPGHPGPPG- 1053
Query: 466 PTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPM-PVPQMMNFGLPSLAPLVPPPTLL 524
P P G P P P P S GP P G A +
Sbjct: 1054 PVGPAGKSGDRGESGPAGP-AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI------- 1105
Query: 525 VPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSP 584
K GF N P APG AG G SP
Sbjct: 1106 -------------------------KGHRGFPGN-----PGAPGSPGPAG--QQGAIGSP 1133
Query: 585 RDSKQGSSKSADSPP---GCSGQALSLAPTPAEHGRSEVVDLTRRAGSP--PGPPGAGGQ 639
+ PP G SG + P R E GSP PG PG G
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE----RGSEGSPGHPGQPGPPGP 1189
Query: 640 LGFPG 644
G PG
Sbjct: 1190 PGAPG 1194
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 75.9 bits (185), Expect = 2e-13
Identities = 137/541 (25%), Positives = 179/541 (33%), Gaps = 117/541 (21%)
Query: 309 RKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQP 368
+K P P TA + P S V D P E ++PP V
Sbjct: 713 KKKPPPRPTAPKPLLPRREESEAVEAGD-----------------PPEELRSLPPDMVAG 755
Query: 369 PA------SIGPPLGVPPRSPPMVMTNRGPV----PLPIFMEQQIMQQIRPPFIRGPPHH 418
P PL PP SP T GP PLP Q I+P R P H
Sbjct: 756 PRLPDTFLGSATPLHFPP-SPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQP---RAPGPH 811
Query: 419 ASNPNSPLSNPMLPG--IGPPPGGPRNLG--PTSSPMHRPMLSPHIHPPSTPTMPGNPPG 474
A P+ PG + P P LG P SSP H + SP++ G
Sbjct: 812 AM--------PVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYV-------------G 850
Query: 475 LLPPPP----PGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVI 530
+ P PP P AP P P ++M + +PS P PT P P
Sbjct: 851 VGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCF 910
Query: 531 VPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQG 590
P+P P P+P P + + +K P P + G P+G +PR Q
Sbjct: 911 -PVPPPQPLPTPYTYPAGAKQP-------------IPAQHHFSSGIPAGFP-APRIGPQP 955
Query: 591 SSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGA-GGQLGFPGVLQGP 649
P G P P +H PP PG Q +P P
Sbjct: 956 QPHPQPHPSQAFGPQPPQQPLPLQHPHL----------FPPQAPGLLPPQSPYP---YAP 1002
Query: 650 QDGVIDLTVG--HRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPG 707
Q GV+ H L AH A PS G + H PP A P
Sbjct: 1003 QPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSP------GPPQPPH--PPLAYGPA 1054
Query: 708 PGA-PAGPEAAAACNVIVNGTRGAAAEGAKSAEP---PPEQPPPPPPPAPPKKLLSPEEP 763
P P GP+AA RG ++ G + P P P P P P PP+ P
Sbjct: 1055 PSTRPMGPQAAPLT------IRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPR-------P 1101
Query: 764 AVSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDK-SDPNLNNPADEDHAYALRMLP 822
+E A+ L + G ++ GG P + A+ ALR++
Sbjct: 1102 PAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIE 1161
Query: 823 K 823
+
Sbjct: 1162 R 1162
Score = 39.3 bits (90), Expect = 0.016
Identities = 47/163 (28%), Positives = 58/163 (35%), Gaps = 46/163 (28%)
Query: 362 PPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASN 421
PP ASI +P S +V+ G VP+ IRPP
Sbjct: 1464 PPCKPLASASISQKNHLPQDSQDLVLG--GDVPISSIQATIAKLSIRPP---------GG 1512
Query: 422 PNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPP 481
SP+++ LPG PPG P P P STP + PPP
Sbjct: 1513 LESPVAS--LPGPAEPPGLP----------------PASLPESTPIPSSS------PPPL 1548
Query: 482 GAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPS-----LAPLVP 519
+PLP P P PVP+ + G PS LA L P
Sbjct: 1549 SSPLPEAP------QPKEEPPVPEAPSSGPPSSSLELLASLTP 1585
Score = 30.8 bits (68), Expect = 5.7
Identities = 20/69 (28%), Positives = 26/69 (37%), Gaps = 10/69 (14%)
Query: 696 GHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPK 755
G P A PGP P G A+ + S+ PPP P P P P +
Sbjct: 1511 GGLESPVASLPGPAEPPGLPPASL----------PESTPIPSSSPPPLSSPLPEAPQPKE 1560
Query: 756 KLLSPEEPA 764
+ PE P+
Sbjct: 1561 EPPVPEAPS 1569
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 75.1 bits (183), Expect = 3e-13
Identities = 178/731 (24%), Positives = 241/731 (32%), Gaps = 192/731 (26%)
Query: 309 RKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVP-KSIPISETPNIPPVSVQ 367
R + + + +G P TVSP + ++P P P S P P VS
Sbjct: 115 RSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQA 174
Query: 368 PPASIGPPLGVPPR-----------SPPMVMTNRGPVPLP------------IFMEQQIM 404
P GP PPR SP + P P P +
Sbjct: 175 FPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALR 234
Query: 405 QQIRPPFIRGPPH-HASNPNSPLSNPML----PGIGPPPGGPRNL-----GPTSSP---- 450
+ P + PP HAS+ SP S+P L + PPP P N GP S P
Sbjct: 235 SSLVPSDLGSPPAPHASS--SPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS 292
Query: 451 --MHRPMLSPHIHPPSTPTMPGNPPGL---------------LPPPP------PGAPLPS 487
MH P++ + T PG PP L LPPP P A PS
Sbjct: 293 ATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS 352
Query: 488 L---------------------------PFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPP 520
P P P P PVPQ + PS P++P
Sbjct: 353 ASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPS-QPILPS 411
Query: 521 PTLLVPYPVIVP---------LPVPIPIPIPIPHVSDSKPPN----------GFSSNGEN 561
L+ P P L +P P P +S PP G +S +
Sbjct: 412 VLSLLGLPTPGPSHSDGSFNLLGSDAHLP-PPPTLSSGSPPQPRHPIQPSLPGTTSGSLS 470
Query: 562 FIPNAPGDSAAAGGK--PSGHSLSPRDS-KQGSSKSADSPPGCSGQA------------- 605
+P AP AA+ PS SP + G+ + PP G+A
Sbjct: 471 SVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALS 530
Query: 606 -------LSLAPTPAEHGR---SEVVD------LTRRAGSPP-----GPPGAGGQLGFPG 644
L P P G+ S +++ LT G PP PPG G PG
Sbjct: 531 GAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPG 590
Query: 645 VLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAG 704
+GP V L + L A +++ A P A T G DG S AG
Sbjct: 591 EPEGPSLLVASLLPPPPSDLLPP-PSAPPSNLLASFLPLLALGPTAG---DGEGSAEGAG 646
Query: 705 DPGPGAPAG----------PEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPP-----P 749
P +G P +A + +N AA + +PP PP P P
Sbjct: 647 GPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAA-----TLDPPSGTPPQPCVLSAP 701
Query: 750 PPAPPKKLL--SPEEPAVSELESVKENNCASNCHLDGEAAKKLMGE-EALAGGDKSDPNL 806
P PP + + +P S L N+ L L+G+ +L + P+L
Sbjct: 702 QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSL 761
Query: 807 NNPADE--DHAYALRMLPKTG-------------CVIQPVPKPAEKAAMAPCI-ISSPML 850
P L++LP G C++Q + P E+ APC+ SP
Sbjct: 762 LQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPE-APCLPPESPAS 820
Query: 851 SAGPEDLEPPL 861
+ PE PPL
Sbjct: 821 ALEPEPARPPL 831
Score = 57.4 bits (137), Expect = 6e-08
Identities = 114/415 (27%), Positives = 148/415 (35%), Gaps = 110/415 (26%)
Query: 299 SWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPS--DTANCSVTKIP-TPVPKSIPI 355
S+N+ +DA P + S G P + PS T + S++ +P P P +
Sbjct: 429 SFNLLGSDAHLPPPPTL-----SSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAA-- 481
Query: 356 SETPNIP-PVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQI----------M 404
S+ P +P PV P +G G PP+ P P P EQ + +
Sbjct: 482 SKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSP---EQGLALSGAGFPGML 538
Query: 405 QQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPS 464
+ P G P P SPL N L G+ GG P P+L P P
Sbjct: 539 GALPLPLSLGQP-----PPSPLLNHSLFGVLTGGGG--------QPPPEPLLPPP-GGPG 584
Query: 465 TPTMPGNPPG-------LLPPPPPGA-PLPSLP--------FPPVSMMPN---------- 498
P PG P G LLPPPP P PS P P +++ P
Sbjct: 585 PPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEG 644
Query: 499 --GPMPVPQMMNFGLPSLAPLV-----PPPTLLV-----------------PYPVIVPLP 534
GP P GL L+PL+ PPTL+ P P ++ P
Sbjct: 645 AGGPSGEPFS---GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP 701
Query: 535 VPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGD-----SAAAGGKPSGHSLSPRDSKQ 589
P P P V+ + G SS G+ P+ G S G G LS S
Sbjct: 702 QPGP---PTSSVTTATTDPGASSLGK--APSNSGRPPQLLSPLLGASLLG-DLSSLTSSP 755
Query: 590 GSSKSADSPPG--CSGQ-ALSL-----APTPAEHGRSEVVDLTRRAGSPPGPPGA 636
G+ S PPG SGQ L L AP P S + L + PP P A
Sbjct: 756 GALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEA 810
Score = 40.4 bits (93), Expect = 0.007
Identities = 54/197 (27%), Positives = 75/197 (38%), Gaps = 47/197 (23%)
Query: 312 PSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPAS 371
P P + GP P++S T + +D S+ K P+ S +PP
Sbjct: 693 PQPCVLSAPQPGP-PTSSVTTATTDPGASSLGKAPSN----------------SGRPPQL 735
Query: 372 IGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPML 431
+ P LG +T+ P LP ++ PP GP + L +L
Sbjct: 736 LSPLLGASLLGDLSSLTS-SPGALPSLLQ--------PP---GPLL-----SGQLGLQLL 778
Query: 432 PGIGPPPGGPRNLGPTSSPMHRPMLSPHIHP--PSTPTMPG-NPPGLLPPPPPGAPLPSL 488
PG G PP L SSP+ + S I P P P +P +P L P P PL +L
Sbjct: 779 PGGGAPPP----LSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSAL 834
Query: 489 ------PFPPVSMMPNG 499
P PPV + G
Sbjct: 835 APPHGSPDPPVPELLTG 851
Score = 31.2 bits (69), Expect = 4.4
Identities = 36/120 (30%), Positives = 48/120 (40%), Gaps = 21/120 (17%)
Query: 272 PAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTT 331
P L S L PP + G+QLL PL++A SP+A QS P
Sbjct: 755 PGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEAS----SPLACLLQSLQIPPE---- 806
Query: 332 VSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRG 391
A C +P P S + P PP+S ++ PP G P P ++T RG
Sbjct: 807 ---QPEAPC----LPPESPASA-LEPEPARPPLS-----ALAPPHGSPDPPVPELLTGRG 853
>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
Length = 663
Score = 74.3 bits (181), Expect = 5e-13
Identities = 114/428 (26%), Positives = 147/428 (34%), Gaps = 92/428 (21%)
Query: 361 IPPVSVQPPASI---GPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPH 417
+PPV V P + PPL R+PP + L Q + P + GPP
Sbjct: 11 VPPVRVYGPDCVVLMEPPLS--KRNPPALRL----ADLATAQVQPLQNMTGFPALAGPPA 64
Query: 418 HASNPNSPLSNPMLPGIGPPPG-GPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLL 476
H S + +++ L +G PG LGP H T+ +PP
Sbjct: 65 H-SQLRAAVAHLRLRDLGADPGVATTPLGPE-------------HMAQASTLGLSPPSQA 110
Query: 477 PPPPPGAPLPSLPFPPVSMMPN-GPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPV 535
P P AP + + P G P G P PPP P P + P P
Sbjct: 111 FPAHPEAPAAAARAAALVAHPGAGSYPC----GGGSSGAQPSAPPP----PAPPLPPTPS 162
Query: 536 PIPIPIPIPHVSDSKPP--NGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSK 593
P P P P P PP +G+++ +S G GHS RD
Sbjct: 163 PPPPPPPPP------PPALSGYTTT----------NSGGGGSSGKGHS---RDFVLRRDL 203
Query: 594 SADSPPGC-----------SGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGF 642
SA +P SG P P H + + G+ GP G+GG F
Sbjct: 204 SATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISAS---GTYAGPDGSGGPALF 260
Query: 643 PGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPA 702
P + P GH L+ + L A A +AAE G PP
Sbjct: 261 PALHDTP-----GAPGGHPHPLNGQMRLGLAAAAAA----AAAELY-------GRAEPPF 304
Query: 703 A---GDPGPGAPAGPEAAA-----ACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPP 754
A GD GA A AAA A N+ +N AAA A PPP PP PP
Sbjct: 305 APRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPP 364
Query: 755 KKLLSPEE 762
P +
Sbjct: 365 APAQHPHQ 372
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/72 (38%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 699 SPPAAGDPG-PGAPAGPEAAAACNVIVNGTR---GAAAEGAKSAEPPPEQPPPPPPPAPP 754
SPP+ P P APA AAA G + GA+ + PPP PP PP P+PP
Sbjct: 105 SPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPP 164
Query: 755 KKLLSPEEPAVS 766
P PA+S
Sbjct: 165 PPPPPPPPPALS 176
Score = 33.1 bits (74), Expect = 1.2
Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 10/86 (11%)
Query: 409 PPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTM 468
PP PP A +P+ +P LPG L P+ + ++ I P +
Sbjct: 357 PPAPPPPPAPAQHPHQ--HHPHLPG-----AAGAFLRYMRQPIKQELICKWIDPDELAGL 409
Query: 469 PGNPPGLLPPPPPGAPLPSLPFPPVS 494
P PP PPPPP P P+ P S
Sbjct: 410 PPPPP---PPPPPPPPPPAGGAKPCS 432
Score = 30.4 bits (67), Expect = 7.5
Identities = 27/90 (30%), Positives = 28/90 (31%), Gaps = 29/90 (32%)
Query: 429 PMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPG------------------ 470
P L PPP P P P PH H P P G
Sbjct: 349 PHLQHHAPPPAPP--------PPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKW 400
Query: 471 -NPPGL--LPPPPPGAPLPSLPFPPVSMMP 497
+P L LPPPPP P P P P P
Sbjct: 401 IDPDELAGLPPPPPPPPPPPPPPPAGGAKP 430
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 73.9 bits (180), Expect = 6e-13
Identities = 72/246 (29%), Positives = 97/246 (39%), Gaps = 47/246 (19%)
Query: 399 MEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSP 458
++ ++ +Q PP PP P P P G PPP R P P P +P
Sbjct: 268 VKNELRRQAPPP----PPPSRGGPPPPPPPPHNSGPPPPPARGRG-APPPPPSRAPTAAP 322
Query: 459 HIHPPSTPTM--PGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAP 516
PPS P++ P PP + PPPP P+LP S P+GP P
Sbjct: 323 PPPPPSRPSVAVPPPPPNRMYPPPP----PALP----SSAPSGPPP-------------- 360
Query: 517 LVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGK 576
PPP++L PV P P P P P P PP G S+G++ +P G+ AA +
Sbjct: 361 --PPPSVLGVGPVAPPPPPPPPPPPGPP------PPPGLPSDGDHQVPTTAGNKAALLDQ 412
Query: 577 PSGHSLSPRDSKQGSSKSADS-PPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPG 635
R+ Q +S P CSG+ L V D + +PP P
Sbjct: 413 -------IREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVAD--GQESTPPTPAP 463
Query: 636 AGGQLG 641
G +G
Sbjct: 464 TSGIVG 469
Score = 56.6 bits (135), Expect = 1e-07
Identities = 49/146 (33%), Positives = 56/146 (38%), Gaps = 33/146 (22%)
Query: 368 PPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLS 427
PP+ GPP PP PP N GP P P + PP PP A P
Sbjct: 281 PPSRGGPP---PPPPPPH---NSGPPPPPA------RGRGAPP---PPPSRAPTAAPPPP 325
Query: 428 NPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPS 487
P P + PP P + P P P +P PP P++ G P PPPPP P
Sbjct: 326 PPSRPSVAVPPPPPNRMYPPPPPA-LPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPP--- 381
Query: 488 LPFPPVSMMPNGPMPVPQMMNFGLPS 513
P GP P P GLPS
Sbjct: 382 ---------PPGPPPPP-----GLPS 393
Score = 54.3 bits (129), Expect = 5e-07
Identities = 46/139 (33%), Positives = 51/139 (36%), Gaps = 23/139 (16%)
Query: 346 PTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQ 405
P P P S P PP + PP G PP P T P P P +
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAV-- 334
Query: 406 QIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPST 465
PP PP + P P + P GPPP P LG + P PP
Sbjct: 335 ---PP----PPPNRMYPPPPPALPSSAPSGPPPPPPSVLG----------VGPVAPPPPP 377
Query: 466 PTMPGNPPGLLPPPPPGAP 484
P P PPG PPPPPG P
Sbjct: 378 PPPP--PPG--PPPPPGLP 392
Score = 44.7 bits (104), Expect = 4e-04
Identities = 50/183 (27%), Positives = 61/183 (33%), Gaps = 42/183 (22%)
Query: 303 PLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIP 362
P +R P P S P P A +P + + T P P P S P P P
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPP 338
Query: 363 PVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNP 422
P + PP PP +P +P GP P PP + G
Sbjct: 339 PNRMYPP----PPPALPSSAP------SGPPP-------------PPPSVLGV------- 368
Query: 423 NSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPG 482
P++ P P PPPG P G S H+ PT GN LL G
Sbjct: 369 -GPVAPPPPPPPPPPPGPPPPPGLPSDGDHQ-----------VPTTAGNKAALLDQIREG 416
Query: 483 APL 485
A L
Sbjct: 417 AQL 419
Score = 38.9 bits (89), Expect = 0.021
Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 20/78 (25%)
Query: 700 PPAAGDPGPGAP----AGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPP----- 750
PP+ G P P P +GP A RG A + P PPPPPP
Sbjct: 281 PPSRGGPPPPPPPPHNSGPPPPPA--------RGRGAPPPPPSRAPTAAPPPPPPSRPSV 332
Query: 751 ---PAPPKKLLSPEEPAV 765
P PP ++ P PA+
Sbjct: 333 AVPPPPPNRMYPPPPPAL 350
Score = 35.0 bits (79), Expect = 0.30
Identities = 18/55 (32%), Positives = 20/55 (36%), Gaps = 12/55 (21%)
Query: 700 PPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPP 754
PPA P P P + G + PPP PPPP PP PP
Sbjct: 347 PPALPSSAPSGPPPPPPSVL------------GVGPVAPPPPPPPPPPPGPPPPP 389
Score = 34.7 bits (78), Expect = 0.40
Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 27/107 (25%)
Query: 738 AEPPPEQPPPPPPPAPPKKLLSPEEPAV-----------------SELESVKENNCASNC 780
A PPP PPPPP P PP L S + V ++L+ V++N+ +C
Sbjct: 372 APPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSC 431
Query: 781 HLDGEAAKKLMGEEALAGGDKSDPNLNNPADEDHAYALRMLPKTGCV 827
G +AL + L + AD + P +G V
Sbjct: 432 ----------SGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIV 468
Score = 33.1 bits (74), Expect = 1.2
Identities = 13/25 (52%), Positives = 14/25 (56%)
Query: 740 PPPEQPPPPPPPAPPKKLLSPEEPA 764
PPP + PPPPP PP P PA
Sbjct: 280 PPPSRGGPPPPPPPPHNSGPPPPPA 304
Score = 30.0 bits (66), Expect = 9.8
Identities = 20/64 (31%), Positives = 23/64 (35%), Gaps = 2/64 (3%)
Query: 700 PPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLS 759
PP G GAP P + A + PPP + PPPPPA P S
Sbjct: 299 PPPPPARGRGAPPPPPSRAP--TAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPS 356
Query: 760 PEEP 763
P
Sbjct: 357 GPPP 360
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 73.9 bits (180), Expect = 6e-13
Identities = 96/348 (27%), Positives = 125/348 (35%), Gaps = 76/348 (21%)
Query: 302 IPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNI 361
IP + P P+ T P P+++ TV+P T PTP P P + P
Sbjct: 769 IPAPLPPQAPPKPLVTI-----PAPTSTKTVAPVVTQAAP----PTPTPPVPPAKKQPAF 819
Query: 362 PPVSVQPPASIGPPLGVPPRSPPMVMTNRG-PVPLPIFMEQQIMQQIRPPFIRGPPHHAS 420
P S PP+ PP+ VPP + P + P P P+ +++QI F PP
Sbjct: 820 P-ASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQF---PP--PP 873
Query: 421 NPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPP 480
P + S P+ P P N+ P S P + P P S P P PPPP
Sbjct: 874 TPPAMESQPLKPV-------PANVAPQSPPAVKA--KPKWQPSSIPV----PSPDFPPPP 920
Query: 481 PGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIP 540
P + SL FPP P P+P P PPP P P P
Sbjct: 921 PES---SLVFPPP---PPSPVPAP--------------PPP------------PPPTASP 948
Query: 541 IPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPG 600
P S K + SS G P P +++ P+ S S +PP
Sbjct: 949 TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPA 1008
Query: 601 CSGQ-ALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQ 647
SG + P PA A PG G + PGVLQ
Sbjct: 1009 ESGSPSKETLPPPA-------------APPKPGKLNLSG-VNLPGVLQ 1042
Score = 66.6 bits (161), Expect = 9e-11
Identities = 119/500 (23%), Positives = 158/500 (31%), Gaps = 99/500 (19%)
Query: 344 KIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGP---VPLPIFME 400
KI TP S P +P +PP PP PP PP PP + + P P+F++
Sbjct: 614 KIVTPYTASQP---SPPLPPPPPPPP----PPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Query: 401 QQIMQQI-----------RPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSS 449
+ ++ +PP PP S P G+ PPP P S
Sbjct: 667 YSTITRLQNASQHSGALFKPP---TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723
Query: 450 PMHRPMLSPHIHPPSTPTMPGNPPGL--------------LPPPPPGAPLPSLPFPPVSM 495
M L P PS P PP L PPPPP P P P P
Sbjct: 724 AM--AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKP 781
Query: 496 MPNGPMP------VPQMMNFGLPSLAPLVPPPTLLVPYPV--IVPLPVPIPIPIPIPHVS 547
+ P P P + P+ P VPP +P I P P P+P+P P +
Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLP 841
Query: 548 D-----SKPPNGFSSNGENFI---------PNAPGDSAAAGGKPSGHSLSPRDSKQGSSK 593
+KPP S + + P P + KP +++P+ +K
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK 901
Query: 594 -----------SADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAG---GQ 639
S D PP +L P P A PP PP A +
Sbjct: 902 PKWQPSSIPVPSPDFPPPPPESSLVFPPPPPS---------PVPAPPPPPPPTASPTPDK 952
Query: 640 LGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCS 699
G PG + ++ I + A + PS + S
Sbjct: 953 SGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGS 1012
Query: 700 PPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKS--------------AEPPPEQP 745
P P P AP P V + G AK+ PP +
Sbjct: 1013 PSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSD 1072
Query: 746 PPPPPPAPPKKLLSPEEPAV 765
PPPPP L E PAV
Sbjct: 1073 FPPPPPETELPLPPIEIPAV 1092
Score = 47.0 bits (110), Expect = 8e-05
Identities = 97/461 (21%), Positives = 137/461 (29%), Gaps = 80/461 (17%)
Query: 443 NLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMP 502
+L P SP + + PS P P PP PPPPP P P L P P+
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPL---PSQSAPSAGSA 660
Query: 503 VPQMMNFGL----------------PSLAPL-----VPPPTLLVPYPVIVPLPVPIPIPI 541
P + + P P+ V P L+ P V+ P P P P P
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 542 PIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGC 601
P ++ KP P AP + P + Q + + PP
Sbjct: 721 PGSAMAQLKP-----------APCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769
Query: 602 SGQALSLAP------TPAEHGRSEVVDLTRRAGSP---PGPPGAGGQLGFPGVLQGPQDG 652
AP PA V + +A P P P A Q FP P
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP 829
Query: 653 VIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPGAPA 712
+ V A PS ++ PP P +
Sbjct: 830 TPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA------SQFPPPPT---PPAMES 880
Query: 713 GPEAAAACNVIVNGTRGAAA----EGAKSAEPPPEQPPPPP------PPAPPKKLLSPEE 762
P NV A + + P P+ PPPPP PP PP + +P
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940
Query: 763 PAVSELESVKENNCASNCHLDGEAAKKLMGEEALAGGDKSDP------NLNNPADEDHAY 816
P + + G KK + + GG K P ++ + + +H
Sbjct: 941 PPPPTASPTPDKS--------GSPGKK-TSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991
Query: 817 ALRMLPKTGCVIQPVPKPAEKAAMAPCIISSPMLSAGPEDL 857
R P ++ PAE + + + P P L
Sbjct: 992 PKR--PSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL 1030
Score = 45.4 bits (106), Expect = 2e-04
Identities = 41/132 (31%), Positives = 51/132 (38%), Gaps = 24/132 (18%)
Query: 740 PPPEQPPPPPPPAPPKKLLSPEEPAVSELESVKENNCASNCHLDGEAAKKLMGEEALAGG 799
PPP PPPPPPP PP L S P+ A+ + +L +G
Sbjct: 632 PPPPPPPPPPPPPPPPPLPSQSAPSAGS---------AAPMFVKYSTITRLQNASQHSGA 682
Query: 800 DKSDPNLNNPADEDHAYALRML-PKTGCV---IQPVPKPAEKAAM-----APCIISSPML 850
P P + + ++L P G V P P P +AM APC S P
Sbjct: 683 LFKPP--TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQF 740
Query: 851 SAGPEDLEPPLK 862
SA P PPLK
Sbjct: 741 SAPP----PPLK 748
Score = 42.4 bits (98), Expect = 0.002
Identities = 66/266 (24%), Positives = 84/266 (31%), Gaps = 39/266 (14%)
Query: 505 QMMNFGLPSLAP-LVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFI 563
+ MN SL P L P P ++ PY P P P+P P P P PP
Sbjct: 596 ESMNRPYTSLVPPLSPQPKIVTPYTASQPSP-PLPPPPPPPPPPPPPPPPP--------P 646
Query: 564 PNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTP----AEHGRSE 619
P P SA PS S +P K + + SG AL PTP ++ + +
Sbjct: 647 PPLPSQSA-----PSAGSAAPMFVKYSTITRLQNASQHSG-ALFKPPTPPVMQSQSVKPQ 700
Query: 620 VVDLTRRAGSPPGPPGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAE 679
++ PP PP G P L IH+ H A
Sbjct: 701 ILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP 760
Query: 680 REPSAAERRTCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAE 739
P PP P P P P T+ A ++A
Sbjct: 761 PTP-----------------PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803
Query: 740 PPPEQPPPP--PPPAPPKKLLSPEEP 763
P P P PP PA P + P P
Sbjct: 804 PTPTPPVPPAKKQPAFPASYIPPSPP 829
Score = 40.4 bits (93), Expect = 0.007
Identities = 84/368 (22%), Positives = 121/368 (32%), Gaps = 61/368 (16%)
Query: 303 PLTDARRK-APSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNI 361
P A+ K PS + P P S+ V P + P P P + P +
Sbjct: 896 PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS 955
Query: 362 PPVSVQPPASIG--PPLGVPPRSPPMVMTNRGPVPLPIFME-QQIMQQIRPPFIRGPPHH 418
P +S G P P R+ + ++ P P ++ + PP G P
Sbjct: 956 PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK 1015
Query: 419 ASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSP---------MHRPMLSPHIHPPSTPTMP 469
+ P P PP G NL + P P+LS S P
Sbjct: 1016 ETLP---------PPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGR-GKDSVVEFP 1065
Query: 470 GNPPGL-LPPPPPGA--PLPSLPFPPV---SMMPNGPMPVPQMMNFGLPSLAPLVPPPT- 522
P PPPPP PLP + P V + P + PQ + S+ PPPT
Sbjct: 1066 SPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKK-APPPTR 1124
Query: 523 ------LLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGK 576
+ I P + +P + P + S PG A
Sbjct: 1125 PKRNDSTRLTQAEISEQPTMATVVPQVP----TSPKSSLSVQ--------PGFLADLNRT 1172
Query: 577 PSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAE---------HGRSEVVD-LTRR 626
S++ S SS+ + + P + ++L P P E +G S + T R
Sbjct: 1173 LQRKSITRHGSL--SSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLR 1230
Query: 627 AGSPPGPP 634
G PP PP
Sbjct: 1231 RGPPPAPP 1238
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 73.6 bits (179), Expect = 8e-13
Identities = 72/244 (29%), Positives = 95/244 (38%), Gaps = 35/244 (14%)
Query: 359 PNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHH 418
P +P + PP PP +PP PP VM P +P PP + PP
Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVP------------PPGM--PP-- 562
Query: 419 ASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPP 478
P+ P LP PPPG P +L P P + PPS + PP +LPP
Sbjct: 563 ------PVMPPSLPTSVPPPGMPPSLSSAGPP-------PVLPPPSLSS--AGPPPVLPP 607
Query: 479 P--PPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVP 536
P AP P +P PP+S P P + G+P P P VP P
Sbjct: 608 PSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVP-EKP 666
Query: 537 IPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPS-GHSLSPRDSKQGSSKSA 595
P +P P S PP + ++ P+ +S A K + +S D G S +A
Sbjct: 667 RPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAA 726
Query: 596 DSPP 599
S P
Sbjct: 727 PSQP 730
Score = 67.0 bits (162), Expect = 7e-11
Identities = 78/259 (30%), Positives = 104/259 (40%), Gaps = 38/259 (14%)
Query: 399 MEQQIM--QQIRPPFIRGPPHHASNPNSP-LSNPMLPGIGPPPGGPRNLGPTSSPMHRPM 455
M+ Q M + PPF+ P+ P P + P+LP PPP P L T P P
Sbjct: 506 MKNQYMGNMSMPPPFV---PYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPP---PG 559
Query: 456 LSPHIHPPSTPTM---PGNPPGLLPP-PPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGL 511
+ P + PPS PT PG PP L PPP P PSL S P +P P + +
Sbjct: 560 MPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLS----SAGPPPVLPPPSLSSTAP 615
Query: 512 PSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPG--- 568
P + PL PP + P P I P VP IP P ++ + P SS +P P
Sbjct: 616 PPVMPL-PPLSSATPPPGIPPPGVPQGIP---PQLTAAPVPPASSSQSSQ-VPEKPRPAL 670
Query: 569 -DSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSE-------- 619
+ + G + P G S+ +S S AL + ++ G E
Sbjct: 671 LPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQP 730
Query: 620 ---VVDL-TRRAGSPPGPP 634
V D+ R G P PP
Sbjct: 731 ITAVKDMPVRSGGLLPDPP 749
Score = 62.4 bits (150), Expect = 2e-09
Identities = 110/442 (24%), Positives = 157/442 (35%), Gaps = 104/442 (23%)
Query: 362 PPVSVQPPASIGPPLGVPPRSP-PMVMTNRGPVP-----LPIFMEQQI--MQQIRPPFIR 413
PP V PP PP+ +P SP P ++ P F EQ + +QQ++ +
Sbjct: 15 PPPPVPPP----PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQK 70
Query: 414 G-----PPHHASNPNSPLSNPMLPGIG------PPPGGPRNLGPTSSPM------HRPML 456
PHH P P P++PG G PPP P GP S H+ +
Sbjct: 71 QMQCVLQPHHLPPPPLP-PPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLH 129
Query: 457 SPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAP 516
PP M P PP PPG+ +P P S MP P P P + S P
Sbjct: 130 HQRDGPPGLVPMELESPPESPPVPPGSYMP----PSQSYMP-PPQPPPSY--YPPTSSQP 182
Query: 517 LVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGK 576
+PP P P P P P + S S + S+ ++++P+ S A+ +
Sbjct: 183 YLPPAQ---PSPSQSPPSQSYLAPTP-SYSSSSSSSQSYLSHSQSYLPS----SQASPSR 234
Query: 577 PSGHSLSPRDSKQGSSKS---ADSPPGC-SGQALSLAPTPAEHGRSEVVDLTRRAGSPPG 632
PS QG SKS A PP G ++ P E G ++A P
Sbjct: 235 PS----------QGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD 284
Query: 633 P----PGAGGQLGFPGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERR 688
P P Q + L L++ R ++H H+ K EP E
Sbjct: 285 PSTMTPQEQQQYWYRQHL---------LSLQQRTKVHLPGHKKGPVVAKDTPEPVKEE-- 333
Query: 689 TCGGCRDGHCSPPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPP 748
+ PA P +P+ E PP E+ PPP
Sbjct: 334 ---------VTVPATSQV-PESPSSEE--------------------PPLPPPNEEVPPP 363
Query: 749 PPPAPPKKLLSPEEPAVSELES 770
PP P+ E+ + +L++
Sbjct: 364 LPPEEPQSEDPEEDARLKQLQA 385
Score = 56.6 bits (135), Expect = 1e-07
Identities = 62/249 (24%), Positives = 92/249 (36%), Gaps = 56/249 (22%)
Query: 343 TKIPTPVPKSIPISETPNIPPVSVQP--PASIGPPLGVPPRSPPMVMTNRGPV------- 393
+++P P+P P P++PP + P PA++ PP PP PP + T+ P
Sbjct: 524 SQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLS 583
Query: 394 ---PLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSP 450
P P+ + PP + P ++ P + P L PPPG P
Sbjct: 584 SAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIP--------- 634
Query: 451 MHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMP--VPQMMN 508
PG P G +PP AP+P S +P P P +P ++
Sbjct: 635 -----------------PPGVPQG-IPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVS 676
Query: 509 FGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPG 568
FG PP T P P + P + P + FSS+ G
Sbjct: 677 FG------SAPPTTYHPPLQSAGPSE---QVNSKAPLSKSALPYSSFSSD------QGLG 721
Query: 569 DSAAAGGKP 577
+S+AA +P
Sbjct: 722 ESSAAPSQP 730
Score = 54.3 bits (129), Expect = 5e-07
Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 21/137 (15%)
Query: 432 PGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFP 491
PG+ PPPG R P P ++ P P + PP +PPPPP PLP P P
Sbjct: 1503 PGMYPPPGSYRPPPPMGKPPGS-IVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP--PPP 1559
Query: 492 PVSMMPNGPMPV----------------PQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPV 535
PV + Q +N S +P +L P PV +P
Sbjct: 1560 PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPP 1619
Query: 536 PIPIPIPIPHVSDSKPP 552
P P+P+ +P + SKPP
Sbjct: 1620 PGPVPMGMPPM--SKPP 1634
Score = 42.4 bits (98), Expect = 0.002
Identities = 46/159 (28%), Positives = 64/159 (40%), Gaps = 33/159 (20%)
Query: 362 PPVSVQPPASIGPPLG--VPPRSPPM---VMTNRGPVPLPIFMEQQIMQQIRPPFIRGPP 416
PP S +PP +G P G V P +PP V R PVP+P PP PP
Sbjct: 1508 PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIP------------PP----PP 1551
Query: 417 HHASNPNSPLSNPMLPGIGPPPGGPRN---LGPTSSP--MHRPMLSPHIHPPSTPTMPGN 471
P P+ P + + L T+ ++ S PS P +P
Sbjct: 1552 PPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLP-- 1609
Query: 472 PPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFG 510
PP + PP P+P + PP+S P PV Q +++G
Sbjct: 1610 PPPVHSSIPPPGPVP-MGMPPMSKPP----PVQQTVDYG 1643
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/200 (24%), Positives = 66/200 (33%), Gaps = 33/200 (16%)
Query: 312 PSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPAS 371
P + T+ G PS S+ P S++ P P + PPV PP S
Sbjct: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLS 625
Query: 372 IG------PPLGVPPRSPPMVMTNRGP------------------VPLPIFMEQQIMQQI 407
PP GVP PP + P +P P+
Sbjct: 626 SATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTY 685
Query: 408 RPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPT 467
PP P N +PLS LP + LG +S+ +P+ +
Sbjct: 686 HPPLQSAGPSEQVNSKAPLSKSALP--YSSFSSDQGLGESSAAPSQPI-------TAVKD 736
Query: 468 MPGNPPGLLPPPPPGAPLPS 487
MP GLLP PP + L S
Sbjct: 737 MPVRSGGLLPDPPRSSYLES 756
Score = 39.3 bits (90), Expect = 0.016
Identities = 34/103 (33%), Positives = 40/103 (38%), Gaps = 23/103 (22%)
Query: 435 GPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAP-----LPSLP 489
G P +L P S + P ++PP P PPPP G P PS P
Sbjct: 1480 GSEPQMADHLPPQESRLQNTSSRPGMYPP--------PGSYRPPPPMGKPPGSIVRPSAP 1531
Query: 490 FPPVSMMPNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVP 532
P S +P PVP + P PPP L P PVI P
Sbjct: 1532 -PARSSVPVTRPPVP---------IPPPPPPPPLPPPPPVIKP 1564
Score = 39.3 bits (90), Expect = 0.016
Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 12/94 (12%)
Query: 678 AEREPSAAERRTCGGCRDGHCSPPAAGDPGP--GAPAGPEAAAACNVIVNGTRGAAAEGA 735
A+ P R R G PP + P P G P G IV + A
Sbjct: 1486 ADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGS--------IVRPSAPPARSSV 1537
Query: 736 KSAEPP-PEQPPPPPPP-APPKKLLSPEEPAVSE 767
PP P PPPPPPP PP ++ P+ AV +
Sbjct: 1538 PVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQ 1571
Score = 38.5 bits (88), Expect = 0.027
Identities = 46/156 (29%), Positives = 58/156 (37%), Gaps = 31/156 (19%)
Query: 496 MPNGPMPVPQMMNFGLPSLAPLVPPPTL--LVPYPVIVP-LPVPIP---IPIPI--PHVS 547
M N MP P + +P P +PPP L +P PV+ P LP +P +P P+ P +
Sbjct: 511 MGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLP 570
Query: 548 DSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALS 607
S PP P P ++AG P L P PP S S
Sbjct: 571 TSVPP-----------PGMPPSLSSAGPPP---VLPPPSLSSAGPPPVLPPPSLS----S 612
Query: 608 LAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFP 643
AP P + A PPG P G G P
Sbjct: 613 TAPPPV-----MPLPPLSSATPPPGIPPPGVPQGIP 643
Score = 37.7 bits (86), Expect = 0.047
Identities = 80/341 (23%), Positives = 111/341 (32%), Gaps = 50/341 (14%)
Query: 272 PAGLCSTLHPPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSP-VATAGQSQGPGPSAST 330
P L ST PP+ +PL P P + G QG P +
Sbjct: 607 PPSLSSTAPPPV------------------MPLPPLSSATPPPGIPPPGVPQGIPPQLTA 648
Query: 331 TVSP--SDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPP-ASIGPPLGVPPRSPPMVM 387
P S + + V + P P P+S + PP + PP S GP V ++P
Sbjct: 649 APVPPASSSQSSQVPEKPRPALLPTPVS-FGSAPPTTYHPPLQSAGPSEQVNSKAP---- 703
Query: 388 TNRGPVPLPIFMEQQIMQQIRP------PFIRGPPHHASN--PNSPLSNPMLPGIGPPPG 439
++ +P F Q + + ++ P + P+ P S+ + GP
Sbjct: 704 LSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFD 763
Query: 440 GPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNG 499
GPR S P P P GN P P G P M+P G
Sbjct: 764 GPRRFEDLGSRCEGPR-------PKGPRFEGNRPDGPRPRYEGHPAEGTK-SKWGMIPRG 815
Query: 500 PMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNG 559
P Q SL+P P P P P P + +P SSN
Sbjct: 816 --PASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQ 873
Query: 560 E-NFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSSKSADSPP 599
+ NF + S AA K + S + S S PP
Sbjct: 874 QKNFKMQSAAFSIAADVK----DVKAAQSNENLSDSQQEPP 910
Score = 32.7 bits (73), Expect = 1.5
Identities = 18/38 (47%), Positives = 18/38 (47%), Gaps = 6/38 (15%)
Query: 737 SAEPPPEQPPP------PPPPAPPKKLLSPEEPAVSEL 768
SA PPP PPP PPP PP L S P V L
Sbjct: 584 SAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPL 621
Score = 31.2 bits (69), Expect = 4.4
Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)
Query: 734 GAKSAEPPPEQPPPPP---PPAPP----KKLLSPEEPAVSELESVKENNCA 777
G S PPP PPPPP P A P +P P+ S S +E + A
Sbjct: 9 GGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLA 59
Score = 31.2 bits (69), Expect = 4.4
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 18/74 (24%)
Query: 700 PPAAGDPGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLS 759
PP G P PG+ P A A + + P +PP P PP PP L
Sbjct: 1515 PPPMGKP-PGSIVRPSAPPARSSV-----------------PVTRPPVPIPPPPPPPPLP 1556
Query: 760 PEEPAVSELESVKE 773
P P + S E
Sbjct: 1557 PPPPVIKPQTSAVE 1570
>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 73.2 bits (178), Expect = 1e-12
Identities = 72/283 (25%), Positives = 106/283 (37%), Gaps = 27/283 (9%)
Query: 295 LTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIP 354
LTP S T + P+ T + PS+ T++PS+T + + PT P S P
Sbjct: 18 LTPSS-----TPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTP 72
Query: 355 ISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRG 414
+ P ++ QP + + P SPP + + P P + P +
Sbjct: 73 TLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTP--SNTPTLTPSNTPTLTP 130
Query: 415 PPHHASNPNS-----PLSNPMLPGIGPPPGGPRNLGPTSSPMHRPML----SPHIHPPST 465
P+S P S P+L R+ PT +P RP+L +P + P ST
Sbjct: 131 SSTPTLTPSSTPTLTPSSRPIL---------TRSSTPTLTPSSRPILTRSSTPTLTPSST 181
Query: 466 PTM-PGNPPGLLPPPPPGAPLPSLPFPPVSMMPN-GPMPVPQMMNFGLPSLAPLVPPPTL 523
PT+ P + P L P P S P S P P P + P+L P P
Sbjct: 182 PTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILT 241
Query: 524 LVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNA 566
P + P P P P ++ S P SN P++
Sbjct: 242 RSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS 284
Score = 62.0 bits (149), Expect = 2e-09
Identities = 62/236 (26%), Positives = 85/236 (36%), Gaps = 10/236 (4%)
Query: 326 PSASTTVSPSDTANCSVTKIPTPVPKSIPI---SETPNIPPVSVQPPASIGPPLGVPPRS 382
PS + T++PS + + PT P S PI S TP + P S P P +
Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63
Query: 383 P---PMVMTNRGPVPLPIFMEQQIMQQIRPPFIR-GPPHHASNPNSPLSNPMLPGIGPPP 438
P P P P Q I+ + P + P + N+P P P
Sbjct: 64 PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPS 123
Query: 439 GGPRNLGPTSSPMHRPMLSPHIHPPSTPTMP-GNPPGLLPPPPPGAPLPSLP-FPPVSMM 496
P L P+S+P P +P + P S P + + P L P P S P P S
Sbjct: 124 NTP-TLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTP 182
Query: 497 PNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPP 552
P P + P+L P P P + P PI P P ++ S P
Sbjct: 183 TLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRP 238
Score = 60.1 bits (144), Expect = 9e-09
Identities = 57/224 (25%), Positives = 84/224 (37%), Gaps = 12/224 (5%)
Query: 331 TVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNR 390
T++PS+T + + PT P S TP + P S QP + + P SPP + +
Sbjct: 1 TLTPSNTPTLTPSSPPTLTP-----SSTPTLTP-SSQPILTRSSTPTLTPSSPPTLTPSN 54
Query: 391 GPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSP 450
P P + P + P L+ P + P P L P+++P
Sbjct: 55 TPTLTP--SNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTL--TPSSPPTLTPSNTP 110
Query: 451 MHRPMLSPHIHPPSTPTM-PGNPPGLLPPPPPGAPLPSLPFPPVSMMPN-GPMPVPQMMN 508
P +P + P +TPT+ P + P L P P S P S P P P +
Sbjct: 111 TLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTR 170
Query: 509 FGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPP 552
P+L P P P + P P P P ++ S P
Sbjct: 171 SSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTP 214
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/193 (27%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 313 SPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPI---SETPNIPPVSVQPP 369
+P T + PS + T++PS T + + PT P S PI S TP + P S
Sbjct: 109 TPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPIL 168
Query: 370 ASIGPPLGVP-------PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNP 422
P P P S P + + P P + I+ + P + P
Sbjct: 169 TRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTP--SSRPILTRSSTPTLTPSSRPILTP 226
Query: 423 NS-----PLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTM-PGNPPGLL 476
+S P S P+L P L P+S+P P +P + P +TPT+ P N P L
Sbjct: 227 SSTPTLTPSSRPILTRSSTP-----TLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLT 281
Query: 477 PPPPPGAPLPSLP 489
P P S P
Sbjct: 282 PSSTPTLTPSSTP 294
Score = 48.5 bits (114), Expect = 3e-05
Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 8/137 (5%)
Query: 438 PGGPRNLGPTSSPMHRPMLSPHIHPPSTPTM-PGNPPGLLPPPPP---GAPLPSL-PFPP 492
P P L P+S+P P P + STPT+ P +PP L P P + P+L P
Sbjct: 12 PSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSST 71
Query: 493 VSMMPNGP---MPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDS 549
++ P+ P P + P+L P PP P + P P P P ++ S
Sbjct: 72 PTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPS 131
Query: 550 KPPNGFSSNGENFIPNA 566
P S+ P++
Sbjct: 132 STPTLTPSSTPTLTPSS 148
Score = 47.4 bits (111), Expect = 6e-05
Identities = 54/208 (25%), Positives = 78/208 (37%), Gaps = 36/208 (17%)
Query: 267 TQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNI---PLTDARRKAPSPVATAGQSQG 323
T +N P TL P + LTP S I T + P+ T +
Sbjct: 121 TPSNTP-----TLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPT 175
Query: 324 PGPSASTTVSPSDTANCSVTKIPTPVPKSIPI---SETPNIPPVSVQPPASIGPPLGVPP 380
PS++ T++PS T + + PT P S PI S TP + P S +P + + P
Sbjct: 176 LTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSS-RPILTPSSTPTLTP 234
Query: 381 RSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPN-SPLSNPMLPGIGPPPG 439
S P++ + P P +S P +P + P L P
Sbjct: 235 SSRPILTRSSTPTLTP----------------------SSTPTLTPSNTPTLTPSNTPTL 272
Query: 440 GPRNLGPTSSPMHRPMLSPHIHPPSTPT 467
P N PT +P P L+P P TP+
Sbjct: 273 TPSNT-PTLTPSSTPTLTPSSTPTLTPS 299
Score = 30.8 bits (68), Expect = 5.7
Identities = 32/129 (24%), Positives = 47/129 (36%), Gaps = 14/129 (10%)
Query: 251 SAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNI-------P 303
S L I + + L TL P + LTP S I
Sbjct: 156 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215
Query: 304 LTDARRKAPSPVATAGQSQGPGP----SASTTVSPSDTANCSVTKIPTPVPKSIPI---S 356
LT + R +P +T + P S++ T++PS T + + PT P + P S
Sbjct: 216 LTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPS 275
Query: 357 ETPNIPPVS 365
TP + P S
Sbjct: 276 NTPTLTPSS 284
>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 73.2 bits (178), Expect = 1e-12
Identities = 72/283 (25%), Positives = 106/283 (37%), Gaps = 27/283 (9%)
Query: 295 LTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIP 354
LTP S T + P+ T + PS+ T++PS+T + + PT P S P
Sbjct: 18 LTPSS-----TPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTP 72
Query: 355 ISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRG 414
+ P ++ QP + + P SPP + + P P + P +
Sbjct: 73 TLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTP--SNTPTLTPSNTPTLTP 130
Query: 415 PPHHASNPNS-----PLSNPMLPGIGPPPGGPRNLGPTSSPMHRPML----SPHIHPPST 465
P+S P S P+L R+ PT +P RP+L +P + P ST
Sbjct: 131 SSTPTLTPSSTPTLTPSSRPIL---------TRSSTPTLTPSSRPILTRSSTPTLTPSST 181
Query: 466 PTM-PGNPPGLLPPPPPGAPLPSLPFPPVSMMPN-GPMPVPQMMNFGLPSLAPLVPPPTL 523
PT+ P + P L P P S P S P P P + P+L P P
Sbjct: 182 PTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILT 241
Query: 524 LVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNA 566
P + P P P P ++ S P SN P++
Sbjct: 242 RSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS 284
Score = 62.0 bits (149), Expect = 2e-09
Identities = 62/236 (26%), Positives = 85/236 (36%), Gaps = 10/236 (4%)
Query: 326 PSASTTVSPSDTANCSVTKIPTPVPKSIPI---SETPNIPPVSVQPPASIGPPLGVPPRS 382
PS + T++PS + + PT P S PI S TP + P S P P +
Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63
Query: 383 P---PMVMTNRGPVPLPIFMEQQIMQQIRPPFIR-GPPHHASNPNSPLSNPMLPGIGPPP 438
P P P P Q I+ + P + P + N+P P P
Sbjct: 64 PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPS 123
Query: 439 GGPRNLGPTSSPMHRPMLSPHIHPPSTPTMP-GNPPGLLPPPPPGAPLPSLP-FPPVSMM 496
P L P+S+P P +P + P S P + + P L P P S P P S
Sbjct: 124 NTP-TLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTP 182
Query: 497 PNGPMPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPP 552
P P + P+L P P P + P PI P P ++ S P
Sbjct: 183 TLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRP 238
Score = 60.1 bits (144), Expect = 9e-09
Identities = 57/224 (25%), Positives = 84/224 (37%), Gaps = 12/224 (5%)
Query: 331 TVSPSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNR 390
T++PS+T + + PT P S TP + P S QP + + P SPP + +
Sbjct: 1 TLTPSNTPTLTPSSPPTLTP-----SSTPTLTP-SSQPILTRSSTPTLTPSSPPTLTPSN 54
Query: 391 GPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSP 450
P P + P + P L+ P + P P L P+++P
Sbjct: 55 TPTLTP--SNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTL--TPSSPPTLTPSNTP 110
Query: 451 MHRPMLSPHIHPPSTPTM-PGNPPGLLPPPPPGAPLPSLPFPPVSMMPN-GPMPVPQMMN 508
P +P + P +TPT+ P + P L P P S P S P P P +
Sbjct: 111 TLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTR 170
Query: 509 FGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPP 552
P+L P P P + P P P P ++ S P
Sbjct: 171 SSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTP 214
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/193 (27%), Positives = 75/193 (38%), Gaps = 23/193 (11%)
Query: 313 SPVATAGQSQGPGPSASTTVSPSDTANCSVTKIPTPVPKSIPI---SETPNIPPVSVQPP 369
+P T + PS + T++PS T + + PT P S PI S TP + P S
Sbjct: 109 TPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPIL 168
Query: 370 ASIGPPLGVP-------PRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNP 422
P P P S P + + P P + I+ + P + P
Sbjct: 169 TRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTP--SSRPILTRSSTPTLTPSSRPILTP 226
Query: 423 NS-----PLSNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTM-PGNPPGLL 476
+S P S P+L P L P+S+P P +P + P +TPT+ P N P L
Sbjct: 227 SSTPTLTPSSRPILTRSSTP-----TLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLT 281
Query: 477 PPPPPGAPLPSLP 489
P P S P
Sbjct: 282 PSSTPTLTPSSTP 294
Score = 48.5 bits (114), Expect = 3e-05
Identities = 38/137 (27%), Positives = 56/137 (40%), Gaps = 8/137 (5%)
Query: 438 PGGPRNLGPTSSPMHRPMLSPHIHPPSTPTM-PGNPPGLLPPPPP---GAPLPSL-PFPP 492
P P L P+S+P P P + STPT+ P +PP L P P + P+L P
Sbjct: 12 PSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSST 71
Query: 493 VSMMPNGP---MPVPQMMNFGLPSLAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDS 549
++ P+ P P + P+L P PP P + P P P P ++ S
Sbjct: 72 PTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPS 131
Query: 550 KPPNGFSSNGENFIPNA 566
P S+ P++
Sbjct: 132 STPTLTPSSTPTLTPSS 148
Score = 47.4 bits (111), Expect = 6e-05
Identities = 54/208 (25%), Positives = 78/208 (37%), Gaps = 36/208 (17%)
Query: 267 TQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNI---PLTDARRKAPSPVATAGQSQG 323
T +N P TL P + LTP S I T + P+ T +
Sbjct: 121 TPSNTP-----TLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPT 175
Query: 324 PGPSASTTVSPSDTANCSVTKIPTPVPKSIPI---SETPNIPPVSVQPPASIGPPLGVPP 380
PS++ T++PS T + + PT P S PI S TP + P S +P + + P
Sbjct: 176 LTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSS-RPILTPSSTPTLTP 234
Query: 381 RSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPN-SPLSNPMLPGIGPPPG 439
S P++ + P P +S P +P + P L P
Sbjct: 235 SSRPILTRSSTPTLTP----------------------SSTPTLTPSNTPTLTPSNTPTL 272
Query: 440 GPRNLGPTSSPMHRPMLSPHIHPPSTPT 467
P N PT +P P L+P P TP+
Sbjct: 273 TPSNT-PTLTPSSTPTLTPSSTPTLTPS 299
Score = 30.8 bits (68), Expect = 5.7
Identities = 32/129 (24%), Positives = 47/129 (36%), Gaps = 14/129 (10%)
Query: 251 SAKCLNQYKMDIFYKETQANLPAGLCSTLHPPMENKAEGTGVQLLTPDSWNI-------P 303
S L I + + L TL P + LTP S I
Sbjct: 156 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPT 215
Query: 304 LTDARRKAPSPVATAGQSQGPGP----SASTTVSPSDTANCSVTKIPTPVPKSIPI---S 356
LT + R +P +T + P S++ T++PS T + + PT P + P S
Sbjct: 216 LTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPS 275
Query: 357 ETPNIPPVS 365
TP + P S
Sbjct: 276 NTPTLTPSS 284
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 72.8 bits (177), Expect = 1e-12
Identities = 106/367 (28%), Positives = 117/367 (31%), Gaps = 55/367 (14%)
Query: 313 SPVATAGQSQGPGPSASTTVS--PSDTANCSVTKIPTPVPKSIPISETPNIPPVSVQPPA 370
SP AG QG P PS K P P+ + P PP Q P
Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPG-----KPQGPPPQGGNQPQGPPPPPGKPQGPP 82
Query: 371 SIG-------PPLGVPPRSPPMVMTNRGPVPLPIFMEQQIMQQIRPPFIRGPPHHASNPN 423
G PP G P PP +R P P + Q P +GPP P
Sbjct: 83 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP--QGPPPPPGKPQ 140
Query: 424 SPL----SNPMLPGIGPPPGGPRNLGPTSSPMHRPMLSPHIHPPSTPTMPGNPPGLLPPP 479
P + P P PPPG P+ P R SP P P GN P PPP
Sbjct: 141 GPPPQGGNKPQGP---PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG-PPP 196
Query: 480 PPGAPLPSLPFPPVSMMPNGPM-------PVPQMMNFGLPSLAPLVPPPTLLVPYPVIVP 532
PPG P P P P GP P PQ N S + PP P P
Sbjct: 197 PPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDN---KSQSARSPPGKPQGPPPQGGN 251
Query: 533 LPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAAGGKPSGHSLSPRDSKQGSS 592
P P P P PP G + P P GG S S SP QG
Sbjct: 252 QPQG---PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG-- 306
Query: 593 KSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPP-----GPPGAGGQLGF----- 642
PP Q P P + + G PP GPP GG
Sbjct: 307 ----PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP 362
Query: 643 PGVLQGP 649
PG QGP
Sbjct: 363 PGKPQGP 369
Score = 72.0 bits (175), Expect = 2e-12
Identities = 109/414 (26%), Positives = 131/414 (31%), Gaps = 112/414 (27%)
Query: 399 MEQQIMQQIRPPFIRG-----PPHHASNPNSPLSNPMLPGIGPPPGGPRNLGPTSSPMHR 453
+ + + Q+ P I G PP + P P S P P PP GG + GP
Sbjct: 19 LNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP------- 71
Query: 454 PMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPS 513
P PG P G PPP G P P PP P GP P G S
Sbjct: 72 ------------PPPPGKPQG---PPPQGGNKPQGPPPPGK--PQGPPPQ------GDKS 108
Query: 514 LAPLVPPPTLLVPYPVIVPLPVPIPIPIPIPHVSDSKPPNGFSSNGENFIPNAPGDSAAA 573
+P PP P P P P P P PP G + P P
Sbjct: 109 RSPRSPPGKPQGPPPQGGNQPQGPPPP---PGKPQGPPPQGGNK------PQGPPPP--- 156
Query: 574 GGKPSGHSLSPRDSKQGSSKSADSPPGCSGQALSLAPTPAEHGRSEVVDLTRRAGSPPGP 633
GKP G P S+S+ SPPG P G ++ G P GP
Sbjct: 157 -GKPQG----PPPQGDNKSRSSRSPPG-------KPQGPPPQGGNQPQGPPPPPGKPQGP 204
Query: 634 PGAGGQLGF----PGVLQGPQDGVIDLTVGHRARLHNVIHRALHAHVKAEREPSAAERRT 689
P GG PG QGP + N A K + P +
Sbjct: 205 PPQGGNKPQGPPPPGKPQGPPP-----------QGDNKSQSARSPPGKPQGPPPQGGNQP 253
Query: 690 CG-----GCRDGHCSPPAAGD-----PGPGAPAGPEAAAACNVIVNGTRGAAAEGAKSAE 739
G G G PP G+ P PG P GP +R + + K
Sbjct: 254 QGPPPPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQGGSK-----SRSSRSPPGKPQG 306
Query: 740 PPPE-----QPPPPPP----------------PAPPKKLLSPEEPAVSELESVK 772
PPP+ Q PPPPP P PP K P S+ S +
Sbjct: 307 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360
Score = 61.6 bits (148), Expect = 3e-09
Identities = 71/248 (28%), Positives = 84/248 (33%), Gaps = 39/248 (15%)
Query: 281 PPMENKAEGTGVQLLTPDSWNIPLTDARRKAPSPVATAGQSQGPGPSASTTVSPSDTANC 340
PP K +G P N P + P P G+ QGP P + S +A
Sbjct: 195 PPPPGKPQGP-----PPQGGNKP------QGPPP---PGKPQGPPPQGD---NKSQSARS 237
Query: 341 SVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVPLPIFME 400
K P P+ + P PP Q P G G P+ PP +GP P
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG---GNKPQGPPPPGKPQGPPPQGGSKS 294
Query: 401 QQIMQQIRPPFIRGPPHHASN--------PNSPLSNPMLPGIGP----PPGGPRNLGPTS 448
+ P +GPP N P P P G P PPG P+ P
Sbjct: 295 RSSRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352
Query: 449 SPMHRPMLSPHIHPPSTPTMPGNPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMN 508
R SP P P GN P PPPP P P P + P GP PQ
Sbjct: 353 GSKSRSARSPPGKPQGPPQQEGNNP--QGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ--- 407
Query: 509 FGLPSLAP 516
G PS P
Sbjct: 408 GGRPSRPP 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.134 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,845,676
Number of Sequences: 37866
Number of extensions: 4004393
Number of successful extensions: 68516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 790
Number of HSP's successfully gapped in prelim test: 1740
Number of HSP's that attempted gapping in prelim test: 21737
Number of HSP's gapped (non-prelim): 24137
length of query: 873
length of database: 18,247,518
effective HSP length: 111
effective length of query: 762
effective length of database: 14,044,392
effective search space: 10701826704
effective search space used: 10701826704
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.