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Search of human proteins with 239748549
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239748549 PREDICTED: hypothetical protein LOC100129791 [Homo
sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239748549 PREDICTED: hypothetical protein LOC100129791 [Homo ... 669 0.0
gi|239742533 PREDICTED: hypothetical protein LOC100129791 [Homo ... 669 0.0
gi|239754018 PREDICTED: hypothetical protein LOC100129791 [Homo ... 662 0.0
gi|157694505 LINE-1 type transposase domain containing 1 [Homo s... 165 6e-41
gi|239751946 PREDICTED: hypothetical protein XP_002348046 [Homo ... 136 3e-32
gi|239746429 PREDICTED: hypothetical protein XP_002344210 [Homo ... 136 3e-32
gi|239757430 PREDICTED: similar to lactation elevated 1 (predict... 135 4e-32
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 52 6e-07
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 52 6e-07
gi|122937514 unc-13 homolog C [Homo sapiens] 52 1e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 50 2e-06
gi|149363685 hypothetical protein LOC23379 [Homo sapiens] 50 4e-06
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 49 6e-06
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 49 6e-06
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 48 1e-05
gi|38044112 restin isoform b [Homo sapiens] 47 2e-05
gi|4506751 restin isoform a [Homo sapiens] 47 2e-05
gi|45439327 periplakin [Homo sapiens] 47 2e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 46 4e-05
gi|71061468 centromere protein E [Homo sapiens] 46 5e-05
gi|214010216 SMC6 protein [Homo sapiens] 46 5e-05
gi|13375848 SMC6 protein [Homo sapiens] 46 5e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 45 7e-05
gi|118498356 kinectin 1 isoform a [Homo sapiens] 45 9e-05
gi|118498368 kinectin 1 isoform c [Homo sapiens] 45 9e-05
gi|33620775 kinectin 1 isoform a [Homo sapiens] 45 9e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 45 9e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 45 9e-05
gi|45446749 kinesin family member 5A [Homo sapiens] 45 1e-04
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 45 1e-04
>gi|239748549 PREDICTED: hypothetical protein LOC100129791 [Homo
sapiens]
Length = 338
Score = 669 bits (1726), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ
Sbjct: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
Query: 61 TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120
TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA
Sbjct: 61 TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120
Query: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD
Sbjct: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
Query: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV
Sbjct: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
Query: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK
Sbjct: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
Query: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM
Sbjct: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
>gi|239742533 PREDICTED: hypothetical protein LOC100129791 [Homo
sapiens]
Length = 338
Score = 669 bits (1726), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ
Sbjct: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
Query: 61 TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120
TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA
Sbjct: 61 TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120
Query: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD
Sbjct: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
Query: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV
Sbjct: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
Query: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK
Sbjct: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
Query: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM
Sbjct: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
>gi|239754018 PREDICTED: hypothetical protein LOC100129791 [Homo
sapiens]
Length = 338
Score = 662 bits (1709), Expect = 0.0
Identities = 335/338 (99%), Positives = 336/338 (99%)
Query: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ
Sbjct: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
Query: 61 TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120
TKGK+VENFEKNLEECITRITNTEKCLKELMELKTKAREL EECRSLRSRCDQLEERVSA
Sbjct: 61 TKGKEVENFEKNLEECITRITNTEKCLKELMELKTKARELCEECRSLRSRCDQLEERVSA 120
Query: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
MEDEMNEMKQEGK REKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD
Sbjct: 121 MEDEMNEMKQEGKFREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
Query: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV
Sbjct: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
Query: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK
Sbjct: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
Query: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM
Sbjct: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
>gi|157694505 LINE-1 type transposase domain containing 1 [Homo
sapiens]
Length = 865
Score = 165 bits (417), Expect = 6e-41
Identities = 94/254 (37%), Positives = 149/254 (58%), Gaps = 7/254 (2%)
Query: 67 ENFEKNLEECITRITNTEKCLKELMELKTK---ARELREECRSLRSRCDQLEERVSAMED 123
E E+NL + I + + +E+ LK+ E+ L SR D LEER+ ++ED
Sbjct: 611 EETEENLRSSV--INSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLED 668
Query: 124 EMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQ 183
++ E ++ K+I E+ ++I + + N+RLIG+PE E + E+ +++II
Sbjct: 669 QIEEFSKDTMQMTKQIISKERQ-RDIEERSRSCNIRLIGIPEK-ESYENRAEDIIKEIID 726
Query: 184 ENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLK 243
ENF L + ++++I R+ + +R TPRHI+V+F KEK++RA+RE+ +T +
Sbjct: 727 ENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQ 786
Query: 244 GKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQML 303
G IRLTADLS +TL AR +W +F +L EK F PRI Y AK++F G+ K F+ +
Sbjct: 787 GTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEF 846
Query: 304 RDFVTTRPALQELL 317
RD+V P L+ELL
Sbjct: 847 RDYVLHMPTLRELL 860
Score = 86.3 bits (212), Expect = 4e-17
Identities = 42/102 (41%), Positives = 69/102 (67%)
Query: 220 RFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPR 279
+F K++ KE++L+A+RE+ + +G + L ADLS+ TL ++W +FNIL+E +F+P+
Sbjct: 216 KFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPK 275
Query: 280 ISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEAL 321
KL+F +GEIK F D Q LR F + + +++ELLK+ L
Sbjct: 276 FLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVL 317
>gi|239751946 PREDICTED: hypothetical protein XP_002348046 [Homo
sapiens]
Length = 132
Score = 136 bits (342), Expect = 3e-32
Identities = 70/132 (53%), Positives = 94/132 (71%), Gaps = 3/132 (2%)
Query: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRR---SNYSELRE 57
M K Q +K NSK Q+AS PPK+ +SSPA EQ W N+FDEL E GFRR +N S+L+E
Sbjct: 1 MRKNQCKKAENSKNQNASSPPKDHNSSPAREQDWTGNEFDELTEVGFRRWVITNSSKLKE 60
Query: 58 DIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEER 117
+ T+ K+V+N EK L++ +T I + EK + +LMELK ARELRE S+ SR DQ EER
Sbjct: 61 HVLTQCKEVKNLEKRLDKLLTGINSLEKNINDLMELKNTARELREAYTSINSRIDQAEER 120
Query: 118 VSAMEDEMNEMK 129
+S +ED++NE+K
Sbjct: 121 ISEIEDQLNEIK 132
>gi|239746429 PREDICTED: hypothetical protein XP_002344210 [Homo
sapiens]
Length = 132
Score = 136 bits (342), Expect = 3e-32
Identities = 70/132 (53%), Positives = 94/132 (71%), Gaps = 3/132 (2%)
Query: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRR---SNYSELRE 57
M K Q +K NSK Q+AS PPK+ +SSPA EQ W N+FDEL E GFRR +N S+L+E
Sbjct: 1 MRKNQCKKAENSKNQNASSPPKDHNSSPAREQDWTGNEFDELTEVGFRRWVITNSSKLKE 60
Query: 58 DIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEER 117
+ T+ K+V+N EK L++ +T I + EK + +LMELK ARELRE S+ SR DQ EER
Sbjct: 61 HVLTQCKEVKNLEKRLDKLLTGINSLEKNINDLMELKNTARELREAYTSINSRIDQAEER 120
Query: 118 VSAMEDEMNEMK 129
+S +ED++NE+K
Sbjct: 121 ISEIEDQLNEIK 132
>gi|239757430 PREDICTED: similar to lactation elevated 1 (predicted)
[Homo sapiens]
Length = 132
Score = 135 bits (341), Expect = 4e-32
Identities = 70/132 (53%), Positives = 94/132 (71%), Gaps = 3/132 (2%)
Query: 1 MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRR---SNYSELRE 57
M K Q +K NSK Q+AS PPK+ +SSPA EQ W N+FDEL E GFRR +N S+L+E
Sbjct: 1 MRKNQCKKAENSKNQNASSPPKDHNSSPAREQDWTGNEFDELTEIGFRRWVITNSSKLKE 60
Query: 58 DIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEER 117
+ T+ K+V+N EK L++ +T I + EK + +LMELK ARELRE S+ SR DQ EER
Sbjct: 61 HVLTQCKEVKNLEKRLDKLLTGINSLEKNINDLMELKNTARELREAYTSINSRIDQAEER 120
Query: 118 VSAMEDEMNEMK 129
+S +ED++NE+K
Sbjct: 121 ISEIEDQLNEIK 132
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/241 (22%), Positives = 111/241 (46%), Gaps = 33/241 (13%)
Query: 22 KECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRIT 81
+E S+ P +E ++ FDE+ A LR+ QT+G+KV+ ++ L
Sbjct: 20 QEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVKEYQMEL-------- 71
Query: 82 NTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKR 141
K L + K KA E+R++ S ++ +E V + E+E++ +K R K I+
Sbjct: 72 ------KYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKN----RLKEIEH 121
Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQ 201
N + ++ + +K + R + E++ ++LE ++ + Q + Q+ ++
Sbjct: 122 NLSKIMKLDNEIKALDSR----KKQMEKDNSELEEKMEKVFQ--------GTDEQLNDLY 169
Query: 202 RMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAA-REKGRVTLKGKPIRLTADLSAETLQA 260
QR + R R ++ ++E K R +EK + ++ ++L AD E ++A
Sbjct: 170 HNHQR--TVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRA 227
Query: 261 R 261
R
Sbjct: 228 R 228
Score = 43.5 bits (101), Expect = 3e-04
Identities = 48/238 (20%), Positives = 98/238 (41%), Gaps = 32/238 (13%)
Query: 58 DIQTKGKKVENFEKNLEECIT---------RITNTEKCLKELMELKTKARELREECRSLR 108
DI+ K K + + K++E I + T K + +L E + ++ E+ R +R
Sbjct: 807 DIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMR 866
Query: 109 SRCD-----------------QLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWD 151
D + EE E+ +K+ G+++ ++K Q L+E D
Sbjct: 867 QDIDTQKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENID 926
Query: 152 YVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRR 211
+KR + +G + EE + L++ + R+ I ++ + +++
Sbjct: 927 NIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYY 986
Query: 212 ATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGK-----PIRLTADLSAETLQARREW 264
T I++F ++M E++ + R+ R T +G+ IR AD + RR +
Sbjct: 987 KTLDQAIMKFHSMKM-EEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNY 1043
Score = 28.9 bits (63), Expect = 6.8
Identities = 31/172 (18%), Positives = 67/172 (38%), Gaps = 11/172 (6%)
Query: 49 RSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKEL-------MELKTKARELR 101
R+ + DIQ +E E L + + + CL ++ MELK R++
Sbjct: 612 RNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIA 671
Query: 102 EECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLI 161
++ L+ L+ V + E E + + +I+ N + +Q+ + ++
Sbjct: 672 QQAAKLQG--IDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTN 729
Query: 162 GVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRAT 213
+ + T L+ Q ++E L+ + +EI+ ++ S T
Sbjct: 730 ELKSEKLQISTNLQRRQQ--LEEQTVELSTEVQSLYREIKDAKEQVSPLETT 779
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/241 (22%), Positives = 111/241 (46%), Gaps = 33/241 (13%)
Query: 22 KECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRIT 81
+E S+ P +E ++ FDE+ A LR+ QT+G+KV+ ++ L
Sbjct: 159 QEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVKEYQMEL-------- 210
Query: 82 NTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKR 141
K L + K KA E+R++ S ++ +E V + E+E++ +K R K I+
Sbjct: 211 ------KYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKN----RLKEIEH 260
Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQ 201
N + ++ + +K + R + E++ ++LE ++ + Q + Q+ ++
Sbjct: 261 NLSKIMKLDNEIKALDSR----KKQMEKDNSELEEKMEKVFQ--------GTDEQLNDLY 308
Query: 202 RMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAA-REKGRVTLKGKPIRLTADLSAETLQA 260
QR + R R ++ ++E K R +EK + ++ ++L AD E ++A
Sbjct: 309 HNHQR--TVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRA 366
Query: 261 R 261
R
Sbjct: 367 R 367
Score = 43.5 bits (101), Expect = 3e-04
Identities = 48/238 (20%), Positives = 98/238 (41%), Gaps = 32/238 (13%)
Query: 58 DIQTKGKKVENFEKNLEECIT---------RITNTEKCLKELMELKTKARELREECRSLR 108
DI+ K K + + K++E I + T K + +L E + ++ E+ R +R
Sbjct: 946 DIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMR 1005
Query: 109 SRCD-----------------QLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWD 151
D + EE E+ +K+ G+++ ++K Q L+E D
Sbjct: 1006 QDIDTQKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENID 1065
Query: 152 YVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRR 211
+KR + +G + EE + L++ + R+ I ++ + +++
Sbjct: 1066 NIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYY 1125
Query: 212 ATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGK-----PIRLTADLSAETLQARREW 264
T I++F ++M E++ + R+ R T +G+ IR AD + RR +
Sbjct: 1126 KTLDQAIMKFHSMKM-EEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNY 1182
Score = 28.9 bits (63), Expect = 6.8
Identities = 31/172 (18%), Positives = 67/172 (38%), Gaps = 11/172 (6%)
Query: 49 RSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKEL-------MELKTKARELR 101
R+ + DIQ +E E L + + + CL ++ MELK R++
Sbjct: 751 RNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIA 810
Query: 102 EECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLI 161
++ L+ L+ V + E E + + +I+ N + +Q+ + ++
Sbjct: 811 QQAAKLQG--IDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTN 868
Query: 162 GVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRAT 213
+ + T L+ Q ++E L+ + +EI+ ++ S T
Sbjct: 869 ELKSEKLQISTNLQRRQQ--LEEQTVELSTEVQSLYREIKDAKEQVSPLETT 918
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 51.6 bits (122), Expect = 1e-06
Identities = 43/186 (23%), Positives = 89/186 (47%), Gaps = 22/186 (11%)
Query: 85 KCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQ 144
K L+ + +++T+ ELR +L+ D++ V ++ E+ +++ G V+ +R R
Sbjct: 248 KELQGISQIETELSELRGHVNALKHSIDEISSSVEVVQSEIEQLRT-GFVQSRRETR--- 303
Query: 145 SLQEIWDYVK-------RPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQI 197
+I DY+K + +LR + V E E +E+ + I+ + I+I
Sbjct: 304 ---DIHDYIKHLGHMGSKASLRFLNVTE---ERFEYVESVVYQILIDKMGFSDAPNAIKI 357
Query: 198 QEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAET 257
+ QR+ + A PR I+V F + ++ +L+ + + LKG I ++ D+
Sbjct: 358 EFAQRIGHQRDCPNAKPRPILVYFETPQQRDSVLKKSYK-----LKGTGIGISTDILTHD 412
Query: 258 LQARRE 263
++ R+E
Sbjct: 413 IRERKE 418
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/267 (21%), Positives = 115/267 (43%), Gaps = 29/267 (10%)
Query: 23 ECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENF---EKNLEECITR 79
ECS S EQ +E + L+ N E +E +Q K ++ E L+E IT+
Sbjct: 1136 ECSHSAKLEQDILEKESIILK----LERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 1191
Query: 80 ITNTEKCLKELMELKTKARE--------LREECRSLRSRCDQLEERVSAMEDEMNEMKQE 131
+TN + +K L++LK + E L+EE + +R L+ + E++ ++K++
Sbjct: 1192 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 1251
Query: 132 GKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLAR 191
+K+IK+ ++ + + D K +++ + + + +L D+ Q L
Sbjct: 1252 LTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL-----DMKQRTIQQLKE 1306
Query: 192 QANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPI-RLT 250
Q N Q E + + + I+ ++ ++E+ + + K + + RL
Sbjct: 1307 QLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLA 1366
Query: 251 ADLSAETLQARREWRPIFNILKEKNFQ 277
+L +W+ N L+ KN Q
Sbjct: 1367 TEL--------EKWKEKCNDLETKNNQ 1385
>gi|149363685 hypothetical protein LOC23379 [Homo sapiens]
Length = 2266
Score = 49.7 bits (117), Expect = 4e-06
Identities = 33/159 (20%), Positives = 70/159 (44%), Gaps = 24/159 (15%)
Query: 50 SNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARE---------- 99
+ Y + +++Q ++ N +EE + +I+ +KC +EL LK + E
Sbjct: 52 TEYQKKCDELQFARRENSNLHHQVEEMLQKISPLQKCQEELGSLKAELEEKKSSLKLYQD 111
Query: 100 -------LREEC-------RSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQS 145
++EEC + L ++ +L+E + +++ E K+ EK K+ ++
Sbjct: 112 THQEYARVKEECLKSDAQKKKLEAKVKKLQEAAVKQTQDFKQLRNEKKILEKEFKKTQER 171
Query: 146 LQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQE 184
L E LR IG S + G+ + ++ +++E
Sbjct: 172 LDEFSKQKNEKELRHIGTQISSDSYGSIDKRKVKLLLKE 210
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 48.9 bits (115), Expect = 6e-06
Identities = 55/281 (19%), Positives = 124/281 (44%), Gaps = 27/281 (9%)
Query: 52 YSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRC 111
Y+E + +++ + ++ K++ T EK KE++ LK+ EL+++ L+ +C
Sbjct: 762 YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC 821
Query: 112 DQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENG 171
+ +E++ A+ E +K+ + +K +E+ + D + + N L+ V + E+
Sbjct: 822 GEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDIN 881
Query: 172 TKLE--NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEK 229
+ +I++ N N Q + + + SS + R KV+
Sbjct: 882 QEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMR-------KVQDSNA 934
Query: 230 MLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFI 289
+ A KG+ + + L A++ A+ ++E I +K + YA +SF
Sbjct: 935 EILANYRKGQEEI----VTLHAEIKAQ----KKELDTIQECIK-------VKYAPIVSF- 978
Query: 290 SEGEIKYFIDKQMLRDFVTTRPALQELLKEAL--NMERNNR 328
E E K+ ++ L+D ++ + + +E + N + N++
Sbjct: 979 EECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDK 1019
Score = 35.4 bits (80), Expect = 0.073
Identities = 56/288 (19%), Positives = 124/288 (43%), Gaps = 47/288 (16%)
Query: 50 SNYSELREDIQTKGKKVENFEKNLE---ECI----TRITNTEKCLKELMELKTKARELRE 102
+NY + +E+I T +++ +K L+ ECI I + E+C E K KA E
Sbjct: 938 ANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEEC-----ERKFKATE--- 989
Query: 103 ECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPN-LRLI 161
+ L+ + + ++ S E+E+ + KQE +K I ++ L++ +++ + +
Sbjct: 990 --KELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERA 1047
Query: 162 GVPESDEENG---------TKLENTLQDIIQEN---------FPNLARQANIQIQEIQRM 203
++DE N T+++N + +++EN NL ++ ++ +++++ +
Sbjct: 1048 LSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEAL 1107
Query: 204 SQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLS---AETLQA 260
+ + + K E+K +E+ VT + + + S AE LQ
Sbjct: 1108 KKSLNG--------TIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQI 1159
Query: 261 RREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVT 308
+ + I+K + K+ +S+ + + KQ L+ T
Sbjct: 1160 KEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLET 1207
Score = 30.0 bits (66), Expect = 3.1
Identities = 34/181 (18%), Positives = 81/181 (44%), Gaps = 18/181 (9%)
Query: 83 TEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRI--- 139
TE+ +L +LK K E LR++ Q E V + + ++ +E K +K +
Sbjct: 526 TEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMC 585
Query: 140 ----KRNEQSLQEIWDYVKRPNLRL-IGVPESDEENGTKLENTLQDIIQENFPNLA---R 191
++ + + E+ K + +L + +P EN ++++L + + E L R
Sbjct: 586 EMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFEN---MKSSLSNEVNEKAKKLVEMER 642
Query: 192 QANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGR----VTLKGKPI 247
+ + EI+++ + + +A + ++K ++ + + E G+ +TLK + +
Sbjct: 643 EHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTL 702
Query: 248 R 248
+
Sbjct: 703 Q 703
Score = 29.6 bits (65), Expect = 4.0
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 12/92 (13%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
EL QT + E +K LE T E ++ ++L+ + EC++L C++
Sbjct: 414 ELSLPSQTSYSENEILKKELE---AMRTFCESAKQDRLKLQNELAHKVAECKALALECER 470
Query: 114 L----EERVSAMEDEMNEMKQ-----EGKVRE 136
+ +E++ +ED + ++++ EGKV++
Sbjct: 471 VKEDSDEQIKQLEDALKDVQKRMYESEGKVKQ 502
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 48.9 bits (115), Expect = 6e-06
Identities = 55/281 (19%), Positives = 124/281 (44%), Gaps = 27/281 (9%)
Query: 52 YSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRC 111
Y+E + +++ + ++ K++ T EK KE++ LK+ EL+++ L+ +C
Sbjct: 775 YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC 834
Query: 112 DQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENG 171
+ +E++ A+ E +K+ + +K +E+ + D + + N L+ V + E+
Sbjct: 835 GEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDIN 894
Query: 172 TKLE--NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEK 229
+ +I++ N N Q + + + SS + R KV+
Sbjct: 895 QEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMR-------KVQDSNA 947
Query: 230 MLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFI 289
+ A KG+ + + L A++ A+ ++E I +K + YA +SF
Sbjct: 948 EILANYRKGQEEI----VTLHAEIKAQ----KKELDTIQECIK-------VKYAPIVSF- 991
Query: 290 SEGEIKYFIDKQMLRDFVTTRPALQELLKEAL--NMERNNR 328
E E K+ ++ L+D ++ + + +E + N + N++
Sbjct: 992 EECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDK 1032
Score = 35.4 bits (80), Expect = 0.073
Identities = 56/288 (19%), Positives = 124/288 (43%), Gaps = 47/288 (16%)
Query: 50 SNYSELREDIQTKGKKVENFEKNLE---ECI----TRITNTEKCLKELMELKTKARELRE 102
+NY + +E+I T +++ +K L+ ECI I + E+C E K KA E
Sbjct: 951 ANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEEC-----ERKFKATE--- 1002
Query: 103 ECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPN-LRLI 161
+ L+ + + ++ S E+E+ + KQE +K I ++ L++ +++ + +
Sbjct: 1003 --KELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERA 1060
Query: 162 GVPESDEENG---------TKLENTLQDIIQEN---------FPNLARQANIQIQEIQRM 203
++DE N T+++N + +++EN NL ++ ++ +++++ +
Sbjct: 1061 LSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEAL 1120
Query: 204 SQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLS---AETLQA 260
+ + + K E+K +E+ VT + + + S AE LQ
Sbjct: 1121 KKSLNG--------TIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQI 1172
Query: 261 RREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVT 308
+ + I+K + K+ +S+ + + KQ L+ T
Sbjct: 1173 KEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLET 1220
Score = 30.0 bits (66), Expect = 3.1
Identities = 34/181 (18%), Positives = 81/181 (44%), Gaps = 18/181 (9%)
Query: 83 TEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRI--- 139
TE+ +L +LK K E LR++ Q E V + + ++ +E K +K +
Sbjct: 539 TEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMC 598
Query: 140 ----KRNEQSLQEIWDYVKRPNLRL-IGVPESDEENGTKLENTLQDIIQENFPNLA---R 191
++ + + E+ K + +L + +P EN ++++L + + E L R
Sbjct: 599 EMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFEN---MKSSLSNEVNEKAKKLVEMER 655
Query: 192 QANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGR----VTLKGKPI 247
+ + EI+++ + + +A + ++K ++ + + E G+ +TLK + +
Sbjct: 656 EHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTL 715
Query: 248 R 248
+
Sbjct: 716 Q 716
Score = 29.6 bits (65), Expect = 4.0
Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 12/92 (13%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
EL QT + E +K LE T E ++ ++L+ + EC++L C++
Sbjct: 427 ELSLPSQTSYSENEILKKELE---AMRTFCESAKQDRLKLQNELAHKVAECKALALECER 483
Query: 114 L----EERVSAMEDEMNEMKQ-----EGKVRE 136
+ +E++ +ED + ++++ EGKV++
Sbjct: 484 VKEDSDEQIKQLEDALKDVQKRMYESEGKVKQ 515
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 47.8 bits (112), Expect = 1e-05
Identities = 53/251 (21%), Positives = 111/251 (44%), Gaps = 28/251 (11%)
Query: 30 TEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLE----ECITRITNTEK 85
T + E + E G +++ E+ I K+++ LE +C+ T +
Sbjct: 1370 TRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQI 1429
Query: 86 CLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEM-NEMKQEGKVREKRIKRNEQ 144
+EL+ +KT ++++C L+ +LE+ V + + M + G+V++ + + E+
Sbjct: 1430 LQEELLSMKT----VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEER 1485
Query: 145 SLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMS 204
+ QEI + +K NL L S E L+ + NF ++ Q ++I++++
Sbjct: 1486 ARQEIAEKLKEVNLFLQAQAASQE--------NLEQFRENNFASMKSQMELRIKDLESEL 1537
Query: 205 QRYSSRRATPRHIIVRFTKVEM-KEKMLRAAREKGRVTLKGKPIRLT---ADLSAETLQA 260
+ + + F K E+ K K L K R +L K + A+++ + L
Sbjct: 1538 SKIKTSQED-------FNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVE 1590
Query: 261 RREWRPIFNIL 271
+++ R +F L
Sbjct: 1591 KQQSRSLFTTL 1601
Score = 31.6 bits (70), Expect = 1.1
Identities = 39/182 (21%), Positives = 77/182 (42%), Gaps = 13/182 (7%)
Query: 55 LREDIQTKGKKVENFEK---NLEECITRITNT--EKCLKELMELKTKARELREECRSLRS 109
LR+ + K +N EK N+++ I + K+ + L+ + +EL EC L+
Sbjct: 1146 LRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKE 1205
Query: 110 RCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEE 169
R Q E + E + +++QE K+ +E SL + R + L + ++
Sbjct: 1206 RQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL----EVTSRYRINLEDETQDLKK 1261
Query: 170 NGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEK 229
++ N LQ+ Q+ R A Q++ + + + T + + K+E +K
Sbjct: 1262 KLGQIRNQLQE-AQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKK---QMDKIEELQK 1317
Query: 230 ML 231
L
Sbjct: 1318 NL 1319
Score = 31.6 bits (70), Expect = 1.1
Identities = 28/146 (19%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
Query: 36 ENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKT 95
E + E R +L++++ KK E +LE N E E +LK
Sbjct: 1205 ERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLED---ETQDLKK 1261
Query: 96 KARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKR 155
K ++R + + + R + M+D +++++ + +K+ ++E+ +
Sbjct: 1262 KLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEEL-----Q 1316
Query: 156 PNLRLIGVPESDEENGTKLENTLQDI 181
NL + E ++E KL Q +
Sbjct: 1317 KNLLNANLSEDEKEQLKKLMELKQSL 1342
Score = 29.6 bits (65), Expect = 4.0
Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 22/158 (13%)
Query: 41 ELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELME-LKTKARE 99
ELR + + R D Q + + +N + +T + +K ++ + + ++
Sbjct: 843 ELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSH 902
Query: 100 LREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR------------------IKR 141
EE + L + L+E ++ + E++ +K + + +EK+ IK+
Sbjct: 903 SHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ 962
Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQ 179
NE++L + + + N RL + + +KLEN Q
Sbjct: 963 NEETLTQT---ISQYNGRLSVLTAENAMLNSKLENEKQ 997
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 47.0 bits (110), Expect = 2e-05
Identities = 51/288 (17%), Positives = 125/288 (43%), Gaps = 22/288 (7%)
Query: 35 MENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELK 94
ME+ ++L+EA + L+ + K ++NF L+ ++ + + K E K
Sbjct: 682 MEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGK 741
Query: 95 TKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVK 154
++ ++LR++ + + LE +A + + + +E + RE ++ +++L E+ +
Sbjct: 742 SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 801
Query: 155 RPNLRLIGVPE---SDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRR 211
L + E E ++ ++Q+ + + Q N+ +++++ + +
Sbjct: 802 TLEKELQILKEKFAEASEEAVSVQRSMQETVNK-LHQKEEQFNMLSSDLEKLRENLADME 860
Query: 212 ATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNIL 271
A +F + + +E+ L A+EK + + ++++ D S++ + E R L
Sbjct: 861 A-------KFREKDEREEQLIKAKEKLENDI-AEIMKMSGDNSSQLTKMNDELR-----L 907
Query: 272 KEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKE 319
KE++ + +L E F+ K + V + QE K+
Sbjct: 908 KERDVE-----ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK 950
Score = 37.4 bits (85), Expect = 0.019
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Query: 35 MENDFDELREAGFRR-SNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMEL 93
++N+ D L+E + ++ +E + + +K+E F K +E + L L E
Sbjct: 1073 LQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEE 1132
Query: 94 KTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
K E R + +LEE S + +++ EMK+ K + SLQ+
Sbjct: 1133 NVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQK 1187
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 47.0 bits (110), Expect = 2e-05
Identities = 51/288 (17%), Positives = 125/288 (43%), Gaps = 22/288 (7%)
Query: 35 MENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELK 94
ME+ ++L+EA + L+ + K ++NF L+ ++ + + K E K
Sbjct: 717 MEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGK 776
Query: 95 TKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVK 154
++ ++LR++ + + LE +A + + + +E + RE ++ +++L E+ +
Sbjct: 777 SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 836
Query: 155 RPNLRLIGVPE---SDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRR 211
L + E E ++ ++Q+ + + Q N+ +++++ + +
Sbjct: 837 TLEKELQILKEKFAEASEEAVSVQRSMQETVNK-LHQKEEQFNMLSSDLEKLRENLADME 895
Query: 212 ATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNIL 271
A +F + + +E+ L A+EK + + ++++ D S++ + E R L
Sbjct: 896 A-------KFREKDEREEQLIKAKEKLENDI-AEIMKMSGDNSSQLTKMNDELR-----L 942
Query: 272 KEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKE 319
KE++ + +L E F+ K + V + QE K+
Sbjct: 943 KERDVE-----ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK 985
Score = 37.4 bits (85), Expect = 0.019
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)
Query: 35 MENDFDELREAGFRR-SNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMEL 93
++N+ D L+E + ++ +E + + +K+E F K +E + L L E
Sbjct: 1108 LQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEE 1167
Query: 94 KTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
K E R + +LEE S + +++ EMK+ K + SLQ+
Sbjct: 1168 NVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQK 1222
Score = 29.3 bits (64), Expect = 5.2
Identities = 41/184 (22%), Positives = 76/184 (41%), Gaps = 25/184 (13%)
Query: 31 EQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRI-TNTEKCLKE 89
EQ E D E E S+ E+ +++ + LE + ++ T E +E
Sbjct: 365 EQLLAERDL-ERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADRE 423
Query: 90 LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEI 149
+EL +L EE R + + L+ RV +++ + K+ RIK EQSL +
Sbjct: 424 KVEL---LNQLEEEKRKV----EDLQFRVEEESITKGDLETQTKLEHARIKELEQSL--L 474
Query: 150 WDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQE--NFPNLARQANIQIQEIQRMSQRY 207
++ K L+ +LE+T + E L + +++QE+ + +R
Sbjct: 475 FEKTKADKLQ------------RELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRL 522
Query: 208 SSRR 211
S +
Sbjct: 523 ESNK 526
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 47.0 bits (110), Expect = 2e-05
Identities = 63/299 (21%), Positives = 127/299 (42%), Gaps = 24/299 (8%)
Query: 26 SSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEK 85
+ P + + + + +E + + LR + + KK + E+ +I E+
Sbjct: 1282 TKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEE 1341
Query: 86 CLKELMELKTKARELR-EECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR------ 138
L + E + +R EE LR+ E + ++++++ E + ++R
Sbjct: 1342 ELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELER 1401
Query: 139 ----IKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQ-- 192
++R Q+ +E V+R RL + + + E K+ +T + ++Q++ P AR+
Sbjct: 1402 QLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQD-PQQAREHA 1460
Query: 193 -ANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAR---EKGRVTLKGKPIR 248
+Q++E Q Q T R + K E+KEK++ + EKG + + R
Sbjct: 1461 LLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQ--R 1518
Query: 249 LTADLSAETLQARR---EWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLR 304
L + L E+ R E + L E F S + +L F+ E K +++Q L+
Sbjct: 1519 LKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKS-SKELDFLREENHKLQLERQNLQ 1576
Score = 35.0 bits (79), Expect = 0.096
Identities = 29/137 (21%), Positives = 63/137 (45%), Gaps = 12/137 (8%)
Query: 78 TRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNE---MKQEGKV 134
TR+ +T + + L++L A+E + L Q E ++ E+ +N+ + + +V
Sbjct: 588 TRVEDTNRKYEHLLQLLDLAQEKVDVANRLEKSLQQSWELLATHENHLNQDDTVPESSRV 647
Query: 135 REKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQAN 194
+ + + E+ + L+G E + + + +TL QE+ P+L RQ
Sbjct: 648 LDSKGQELAAMACEL-----QAQKSLLGEVEQNLQAAKQCSSTLASRFQEHCPDLERQE- 701
Query: 195 IQIQEIQRMSQRYSSRR 211
E+ ++ QR+++ R
Sbjct: 702 ---AEVHKLGQRFNNLR 715
Score = 35.0 bits (79), Expect = 0.096
Identities = 64/308 (20%), Positives = 126/308 (40%), Gaps = 47/308 (15%)
Query: 35 MENDFDELREAGFRRSNYSELRED----IQTKGKKVENFEKNLEECIT--RITNTEKCLK 88
+E ++ +L+E R+ E +E+ +Q K K++E E IT + EK
Sbjct: 1066 LEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAA 1125
Query: 89 ELMELKTKARELREECRSLRS---RCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQS 145
E+ R+ +E R+ +L ++ A+E+E ++ + KVRE ++ + ++
Sbjct: 1126 TEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVRE-IVRPDPKA 1184
Query: 146 LQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQ 205
E+ NLRL V + + G E L+ E R ++++E+ +
Sbjct: 1185 ESEV------ANLRLELVEQERKYRGA--EEQLRSYQSELEALRRRGPQVEVKEVTKEVI 1236
Query: 206 RYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWR 265
+Y T EM++++ R E T RL E Q ++E +
Sbjct: 1237 KYK-------------TDPEMEKELQRLREEIVDKT------RLIERCDLEIYQLKKEIQ 1277
Query: 266 PIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEALNMER 325
+ K+ +P++ + I +++ D Q + + R L E K+ +++ER
Sbjct: 1278 AL------KDTKPQVQTKEVVQEI----LQFQEDPQTKEEVASLRAKLSEEQKKQVDLER 1327
Query: 326 NNRYQPLQ 333
Q Q
Sbjct: 1328 ERASQEEQ 1335
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/220 (19%), Positives = 100/220 (45%), Gaps = 25/220 (11%)
Query: 40 DELREAGFRRSNYSELR----EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKT 95
D++++ F+ S+ + E + K ++K + T+ NT K L+ +ELK+
Sbjct: 1412 DQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKS 1471
Query: 96 K-ARELREECRSLRSRCDQLEERVSA----MEDEMNEMKQEGKVREKRIKRNEQSLQEIW 150
K A E E+ L+ DQ +R MED+ ++M+++ E +K + E+
Sbjct: 1472 KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELE 1531
Query: 151 DYVKRPNLRLIGVPESDEENGTKLENTLQDIIQ--ENFPNLARQANIQIQE--------- 199
D++ + + + + E + + + ++++Q ++F L + + +++E
Sbjct: 1532 DHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLE 1591
Query: 200 --IQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREK 237
+ M +++ H+ + V+ KE+ L+A ++
Sbjct: 1592 NQVYSMKAELETKKKELEHVNL---SVKSKEEELKALEDR 1628
Score = 39.7 bits (91), Expect = 0.004
Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 34/242 (14%)
Query: 90 LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEI 149
L E + K R+L++E + R+R +LE S++E + E K + K ++ +
Sbjct: 548 LTESENKLRDLQQEAETYRTRILELE---SSLEKSLQENKNQSKDLAVHLEAEK------ 598
Query: 150 WDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSS 209
+ N + + E + L++ + E L +Q ++++++ ++
Sbjct: 599 ----NKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 654
Query: 210 RRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFN 269
+ II + EM EK L ++ +K + + +E L+AR + +
Sbjct: 655 TLLKDKEIIFQAHIEEMNEKTLE------KLDVKQTELESLSSELSEVLKARHKLEEELS 708
Query: 270 ILKEKNFQPRISYAAKL------------SFISEGEIKYFIDKQMLRDFVTTRPALQELL 317
+LK++ + + AK+ S I E E+ ++ L+D + L+ LL
Sbjct: 709 VLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN---QLELLL 765
Query: 318 KE 319
KE
Sbjct: 766 KE 767
Score = 38.1 bits (87), Expect = 0.011
Identities = 61/273 (22%), Positives = 111/273 (40%), Gaps = 31/273 (11%)
Query: 57 EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
+ Q G++ +N K EE I + N +K EL+TK +EL S++S+ EE
Sbjct: 1567 QHFQELGEEKDNRVKEAEEKILTLENQVYSMKA--ELETKKKELEHVNLSVKSK----EE 1620
Query: 117 RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLEN 176
+ A+ED + E + K+ E + ++ EQ + I +L+ E EE K
Sbjct: 1621 ELKALEDRL-ESESAAKLAELK-RKAEQKIAAI-------KKQLLSQMEEKEEQYKKGTE 1671
Query: 177 TLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAARE 236
+ + R+ +I ++++ + S PR E +E + +
Sbjct: 1672 SHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQ 1731
Query: 237 KGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKY 296
K T + K L +L+ + +R + + +F+ R Y +L + E K
Sbjct: 1732 K---TYEEKISVLQRNLTEKEKLLQRVGQEKEETV-SSHFEMRCQYQERLIKLEHAEAKQ 1787
Query: 297 FIDKQMLRDFVTTRPALQELLKEALNMERNNRY 329
D+ M+ LQE L+ E+N +Y
Sbjct: 1788 HEDQSMIGH-------LQEELE-----EKNKKY 1808
Score = 37.7 bits (86), Expect = 0.015
Identities = 41/201 (20%), Positives = 92/201 (45%), Gaps = 31/201 (15%)
Query: 88 KELMELKTKARELREECRSLRSR----CDQLEERVSAMEDEMNEMKQEGKVREKRIKRNE 143
++L++L+T+ L ++ + ++ C +L+ ++D M +++++ E+++K
Sbjct: 826 QKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK--- 882
Query: 144 QSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRM 203
SL +++ ES E+G K + + I+ E + + Q +EI+ +
Sbjct: 883 -SLTQVY--------------ESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEIL 927
Query: 204 SQRYSSRRATPRHIIVRF-TKVEMKEKMLRAAREKGR---VTLKGKPIRLTADLSAETLQ 259
+Q+ S++ + + + TK + +EK + ++K + TLK K + A L E
Sbjct: 928 TQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELEN 987
Query: 260 ARREWRPIFNILKEKNFQPRI 280
E KEK F ++
Sbjct: 988 TALELSQ-----KEKQFNAKM 1003
Score = 35.8 bits (81), Expect = 0.056
Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 16/145 (11%)
Query: 36 ENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKT 95
+ + ++LRE E ++ K K++ F+ ++EE EK L++L +T
Sbjct: 639 QTEMEKLREK-------CEQEKETLLKDKEII-FQAHIEEM------NEKTLEKLDVKQT 684
Query: 96 KARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKR 155
+ L E + +LEE +S ++D+ ++MKQE + + K + Q Q++ +K
Sbjct: 685 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQ--QQVDSIIKE 742
Query: 156 PNLRLIGVPESDEENGTKLENTLQD 180
+ + ++ ++ +LE L++
Sbjct: 743 HEVSIQRTEKALKDQINQLELLLKE 767
Score = 32.0 bits (71), Expect = 0.81
Identities = 50/258 (19%), Positives = 110/258 (42%), Gaps = 18/258 (6%)
Query: 71 KNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQ 130
K LE R+ E LK E + +E+C L S + L+E++ E+ ++K
Sbjct: 279 KTLETLQQRVKRQENLLKRCKET---IQSHKEQCTLLTSEKEALQEQLDERLQELEKIKD 335
Query: 131 EGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLA 190
+ ++ + + + + +++ +I E+ + LE ++I Q +
Sbjct: 336 LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIA--ETKRQMHETLEMKEEEIAQ--LRSRI 391
Query: 191 RQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLT 250
+Q Q +E++ Q+ S RA + + + E+ R + K + + K I T
Sbjct: 392 KQMTTQGEELR--EQKEKSERAAFEELEKALSTAQKTEEARR--KLKAEMDEQIKTIEKT 447
Query: 251 ADLSAETLQAR--REWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVT 308
++ +LQ R + + +++K+ + + AKL + E E+ ++++ + T
Sbjct: 448 SEEERISLQQELSRVKQEVVDVMKKSSEE----QIAKLQKLHEKELAR-KEQELTKKLQT 502
Query: 309 TRPALQELLKEALNMERN 326
QE +K AL ++
Sbjct: 503 REREFQEQMKVALEKSQS 520
Score = 29.3 bits (64), Expect = 5.2
Identities = 22/115 (19%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 31 EQSWMENDFDELREAGFRR-SNYSELREDIQTKGKKVENFEKNLEECITRITNTE----K 85
E+ M + L+E G ++ + +EL+E ++ K V + ++ + + E K
Sbjct: 1086 EKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNK 1145
Query: 86 CLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIK 140
LKE L+ + EL+ + + +L ++ ++E +K + K ++
Sbjct: 1146 SLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1200
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 45.8 bits (107), Expect = 5e-05
Identities = 48/237 (20%), Positives = 107/237 (45%), Gaps = 7/237 (2%)
Query: 92 ELKTKARE---LREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
E+K+ A+E L+ L+S DQL+E + + + E ++E KV +K E+++ E
Sbjct: 1436 EMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINE 1495
Query: 149 IWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYS 208
+ + + + + E KL+N +Q+I ++ +Q + +++ + Q
Sbjct: 1496 LRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKE 1555
Query: 209 SRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKP--IRLTADLSAETLQARREWRP 266
R+A + +K+ L+ ++E+ ++ +K K R+ L E Q + +
Sbjct: 1556 HRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKE 1615
Query: 267 IFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEALNM 323
I + K K Q + K++ ++E + K + + F T + L+ + E + +
Sbjct: 1616 I--VAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRL 1670
Score = 43.5 bits (101), Expect = 3e-04
Identities = 47/240 (19%), Positives = 104/240 (43%), Gaps = 29/240 (12%)
Query: 22 KECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRIT 81
+ C E+ E +L+E + N E ++Q K ++EN + L+ +
Sbjct: 1117 RTCDRLAEVEEKLKEKS-QQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175
Query: 82 NTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEM------------- 128
+ E E +EL K E EE +S+ L+E + E E + +
Sbjct: 1176 HMET---ERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQ 1232
Query: 129 -KQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDI--IQEN 185
K+E K+ +K +++++ E+ V ++I + E++ TKL+ + + QE
Sbjct: 1233 TKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDL-EKSHTKLQEEIPVLHEEQEL 1291
Query: 186 FPNLARQANIQ--IQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLK 243
PN+ + Q + E++ ++++ +++ +T ++EM+ L ++ + +K
Sbjct: 1292 LPNVKEVSETQETMNELELLTEQSTTKDST------TLARIEMERLRLNEKFQESQEEIK 1345
Score = 39.7 bits (91), Expect = 0.004
Identities = 34/216 (15%), Positives = 101/216 (46%), Gaps = 21/216 (9%)
Query: 40 DELREAGFRRSNYSELREDIQTKGKKVENFEKNLEEC-----------ITRITNTEKCLK 88
++++E L++D+ KKV E+ ++ I + +K +
Sbjct: 1820 EKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHE 1879
Query: 89 ELMELKTKARE---LREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQS 145
L E+K+ +E LR +L+ DQL+E + + E++QE K K ++++
Sbjct: 1880 NLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKET 1939
Query: 146 LQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANI-----QIQEI 200
+ ++ + + +++ + + +++ +L+ +Q++ ++ L + ++ +I E+
Sbjct: 1940 VDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEM 1999
Query: 201 QRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAARE 236
+++ +++ ++ + + VR ++ +K+ + E
Sbjct: 2000 EQLKKQFEAQNLSMQS--VRMDNFQLTKKLHESLEE 2033
Score = 33.9 bits (76), Expect = 0.21
Identities = 59/277 (21%), Positives = 123/277 (44%), Gaps = 23/277 (8%)
Query: 55 LREDIQTKGKKVENFE-KNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
L+E +T+ +EN E +N+ +T+I + L+E+ + + +LR +L+ DQ
Sbjct: 1649 LKEQFETQKLNLENIETENIR--LTQILHEN--LEEMRSVTKERDDLRSVEETLKVERDQ 1704
Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTK 173
L+E + E ++E K+ +K +++++ ++ V + + + E +
Sbjct: 1705 LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA 1764
Query: 174 LENTLQDI-IQENFPNLARQANIQIQEIQR--------MSQRYSSRRATPRHIIVRFTKV 224
L+ QD+ IQE R A++ ++E Q +S++ + + K+
Sbjct: 1765 LK--AQDLKIQEEL----RIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKL 1818
Query: 225 EMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAA 284
+ K + L+ A E +TLK K + T +E Q +++ + L + + ++ A
Sbjct: 1819 QEKIQELK-ANEHQLITLK-KDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIE-NLNLAQ 1875
Query: 285 KLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEAL 321
KL E ++ LR T ++ LKE+L
Sbjct: 1876 KLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESL 1912
Score = 33.5 bits (75), Expect = 0.28
Identities = 65/353 (18%), Positives = 150/353 (42%), Gaps = 28/353 (7%)
Query: 4 KQSRKTGNSKKQSASPPPKECSSSPATEQSW--MENDFDELREAGFRRSNYSELREDIQT 61
K+ ++T + ++S S + ++ E+S ++ + L E N E+ E +T
Sbjct: 1245 KEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQET 1304
Query: 62 KGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAM 121
+ E++ + T + E E + L K +E +EE +SL D L+ A+
Sbjct: 1305 MNELELLTEQSTTKDSTTLARIEM---ERLRLNEKFQESQEEIKSLTKERDNLKTIKEAL 1361
Query: 122 EDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPN--LRLIGVPESDEENGTKLENT-- 177
E + +++K+ + +I+ ++ ++ + ++ N +++ E + + L
Sbjct: 1362 EVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEI 1421
Query: 178 ----LQDIIQENFPNLARQANIQ--IQEIQRMSQRYSSR-RATPRHIIVRFTKVEMKEKM 230
L +QE+ + A + +Q +Q + Q S + + + I+ + + E + K+
Sbjct: 1422 EMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKV 1481
Query: 231 LRAAREKGRVTLKGKPIRLT-ADLSAETLQARREW--RPIFNILKEKNFQPRISYAAKLS 287
++ T+ + L+ + T+Q + E + N ++E + ++S
Sbjct: 1482 AHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQIS 1541
Query: 288 FISE--GEIKYFIDKQMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
+ E E+K F + + +D ALQ + E+ +E NR Q Q ++
Sbjct: 1542 EVQEKVNELKQFKEHRKAKD-----SALQSI--ESKMLELTNRLQESQEEIQI 1587
Score = 30.8 bits (68), Expect = 1.8
Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 9/113 (7%)
Query: 40 DELREAGFRRSNYSELRE---DIQTKGKKVEN----FEKNLEECITRITNTEKCLKELME 92
D RE+ F RS EL+E ++ T K++EN ++ LE + EK L+
Sbjct: 636 DAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFN 695
Query: 93 LKTKARELREECRSLRSRCD-QLEERVSAMEDEMN-EMKQEGKVREKRIKRNE 143
TK L + C+ +LE +++ ++ E+N E+++ +RE+ I +E
Sbjct: 696 EITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSE 748
Score = 29.6 bits (65), Expect = 4.0
Identities = 25/152 (16%), Positives = 68/152 (44%), Gaps = 6/152 (3%)
Query: 56 REDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLE 115
++D+ T ++ ++ + T + E+ K ++E + + +E +L + +
Sbjct: 802 KDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLE---ENERMNQEIVNLSKEAQKFD 858
Query: 116 ERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLE 175
+ A++ E++ QE + + + ++ ++++ + ++ + L V KL+
Sbjct: 859 SSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQ 918
Query: 176 NTLQDI---IQENFPNLARQANIQIQEIQRMS 204
TL+++ QE Q ++QI+ Q S
Sbjct: 919 QTLEEVKTLTQEKDDLKQLQESLQIERDQLKS 950
Score = 28.9 bits (63), Expect = 6.8
Identities = 19/110 (17%), Positives = 59/110 (53%), Gaps = 5/110 (4%)
Query: 35 MENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELK 94
++N E+ E + N ++ E +Q K +++ F+++ + + + + E +++EL
Sbjct: 1521 LQNKIQEIYEKE-EQFNIKQISE-VQEKVNELKQFKEHRKAKDSALQSIES---KMLELT 1575
Query: 95 TKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQ 144
+ +E +EE + + ++++ A++ E +++K+ K ++K +++
Sbjct: 1576 NRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQE 1625
>gi|214010216 SMC6 protein [Homo sapiens]
Length = 1091
Score = 45.8 bits (107), Expect = 5e-05
Identities = 46/238 (19%), Positives = 102/238 (42%), Gaps = 26/238 (10%)
Query: 26 SSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEK 85
SS T ++ D D S S+L +++ K ++ N +++L I + E+
Sbjct: 651 SSENTRPKFLSRDVD---------SEISDLENEVENKTAQILNLQQHLSALEKDIKHNEE 701
Query: 86 CLKELM----ELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKR 141
LK ELK K R+ E R L + + ++ +EDE E K + K+ E+ +++
Sbjct: 702 LLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQ 761
Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQ 201
+++++ +L+ + + ++ + K + + + + A+ ++ +
Sbjct: 762 QKENME---------HLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQK 812
Query: 202 RMSQRYSSRRATPRHII-VRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETL 258
R + Y ++ + + +++MKEK L + R P R+ + SA L
Sbjct: 813 RGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQIC---PERIEVEKSASIL 867
>gi|13375848 SMC6 protein [Homo sapiens]
Length = 1091
Score = 45.8 bits (107), Expect = 5e-05
Identities = 46/238 (19%), Positives = 102/238 (42%), Gaps = 26/238 (10%)
Query: 26 SSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEK 85
SS T ++ D D S S+L +++ K ++ N +++L I + E+
Sbjct: 651 SSENTRPKFLSRDVD---------SEISDLENEVENKTAQILNLQQHLSALEKDIKHNEE 701
Query: 86 CLKELM----ELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKR 141
LK ELK K R+ E R L + + ++ +EDE E K + K+ E+ +++
Sbjct: 702 LLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQ 761
Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQ 201
+++++ +L+ + + ++ + K + + + + A+ ++ +
Sbjct: 762 QKENME---------HLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQK 812
Query: 202 RMSQRYSSRRATPRHII-VRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETL 258
R + Y ++ + + +++MKEK L + R P R+ + SA L
Sbjct: 813 RGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQIC---PERIEVEKSASIL 867
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 45.4 bits (106), Expect = 7e-05
Identities = 64/301 (21%), Positives = 128/301 (42%), Gaps = 38/301 (12%)
Query: 31 EQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKEL 90
E S + + D+L+E + ++Q + VE KN+E +R +NT + +
Sbjct: 770 EVSSHDQEMDKLKE---------QYDAELQALRESVEEATKNVEVLASR-SNTSEQDQAG 819
Query: 91 MELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMK-QEGKVRE--KRIKRNEQSLQ 147
E++ K L+EE L+ R ++LE RV+ ++ ++ ++K E K +E K+ + + L+
Sbjct: 820 TEMRVKL--LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLE 877
Query: 148 EIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQE--NFPNLARQANIQIQEIQRMSQ 205
E + ++ + + E + L QE ++ + Q ++++R+
Sbjct: 878 EALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN 937
Query: 206 RYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWR 265
+ R I + K EM + ++ A+R + L L + RRE
Sbjct: 938 EMENERWHLGKTIEKLQK-EMAD-IVEASRT--------STLELQNQLDEYKEKNRRELA 987
Query: 266 PIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDF-------VTTRPALQELLK 318
+ LKEK + S + E + ++ LRD+ +T R L++ LK
Sbjct: 988 EMQRQLKEKTLEAEKSRLTAMKMQDEMRLM----EEELRDYQRAQDEALTKRQLLEQTLK 1043
Query: 319 E 319
+
Sbjct: 1044 D 1044
Score = 32.7 bits (73), Expect = 0.47
Identities = 45/211 (21%), Positives = 93/211 (44%), Gaps = 24/211 (11%)
Query: 31 EQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFE----KNLEECITRITNTEKC 86
E+ M + +ELR S ++E E+ T +++E E KNLEE E+
Sbjct: 643 ERERMRANLEELR------SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 87 LKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSL 146
E+ +L+ + E+ +E S + D+ A+ +E+ + KQ+ +++ I + EQ
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDR---EKGALIEELLQAKQD--LQDLLIAKEEQE- 750
Query: 147 QEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQR 206
D +++ L + + +E + + + D ++E + + ++E + +
Sbjct: 751 ----DLLRKRERELTALKGALKEEVSSHDQEM-DKLKEQYDAELQALRESVEEATKNVEV 805
Query: 207 YSSRRATPRHIIVRFTKVEMKEKMLRAAREK 237
+SR T EM+ K+L+ EK
Sbjct: 806 LASRSNTSEQ---DQAGTEMRVKLLQEENEK 833
Score = 29.6 bits (65), Expect = 4.0
Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 66 VENFEKNLEECITRITNTEKCLKELM----ELKTKAREL----REECRSLRSRCDQLEER 117
V E + E R+ + E+ L L+ K +EL +E SL + DQL R
Sbjct: 1148 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 1207
Query: 118 VSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWD 151
+ AM+ ++ E ++E E K+ ++ L+E D
Sbjct: 1208 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD 1241
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 45.1 bits (105), Expect = 9e-05
Identities = 41/222 (18%), Positives = 102/222 (45%), Gaps = 30/222 (13%)
Query: 30 TEQSWMENDFDELREAGFRRSNYS----ELREDIQTKGKKVENFEKNLEECITRITNTEK 85
TE S + + +L+ + +++ EL++ I K K+++ E+ LE + ++ N EK
Sbjct: 770 TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEK 829
Query: 86 CLKEL-MELKTKAREL------REECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR 138
+++L E+K E+ + + S+ S+ +L+ + E++MN MK + +EK
Sbjct: 830 TVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKD 889
Query: 139 IKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQ 198
+ + LQ++ +E L+ +Q++ Q N + + +
Sbjct: 890 LANTGKWLQDL------------------QEENESLKAHVQEVAQHNLKEASSASQFEEL 931
Query: 199 EIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
EI + ++ + + + R + + K ++L+ +++ ++
Sbjct: 932 EIV-LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL 972
Score = 35.4 bits (80), Expect = 0.073
Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 22/185 (11%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
EL + I K K+++ E +L R+T+ E+ LK++ + L+ E + L++
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL---LKAEVQKLQA---- 656
Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQ-EIWDYVKRPNLRLIGVPESDEENGT 172
L +A E+ +M+Q V++ +I+ E+ LQ EI + K +++ +D+
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN--KMEEFKIL----NDQNKAL 710
Query: 173 KLE-NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHII-VRFTKVEMKEKM 230
K E LQ ++ E PN ++++++ Q + T ++ +V KE+
Sbjct: 711 KSEVQKLQTLVSEQ-PN-----KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEE 764
Query: 231 LRAAR 235
L A R
Sbjct: 765 LNAIR 769
Score = 29.6 bits (65), Expect = 4.0
Identities = 18/93 (19%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 57 EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
E ++++ K +EN + E + EK E T+ REL++ L+ + D
Sbjct: 1190 ERLRSENKDIENLRREREHLEMEL---EKAEMERSTYVTEVRELKDLLTELQKKLDDSYS 1246
Query: 117 RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEI 149
+E+N +K + +++ + Q++
Sbjct: 1247 EAVRQNEELNLLKAQLNETLTKLRTEQNERQKV 1279
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 45.1 bits (105), Expect = 9e-05
Identities = 41/222 (18%), Positives = 102/222 (45%), Gaps = 30/222 (13%)
Query: 30 TEQSWMENDFDELREAGFRRSNYS----ELREDIQTKGKKVENFEKNLEECITRITNTEK 85
TE S + + +L+ + +++ EL++ I K K+++ E+ LE + ++ N EK
Sbjct: 770 TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEK 829
Query: 86 CLKEL-MELKTKAREL------REECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR 138
+++L E+K E+ + + S+ S+ +L+ + E++MN MK + +EK
Sbjct: 830 TVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKD 889
Query: 139 IKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQ 198
+ + LQ++ +E L+ +Q++ Q N + + +
Sbjct: 890 LANTGKWLQDL------------------QEENESLKAHVQEVAQHNLKEASSASQFEEL 931
Query: 199 EIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
EI + ++ + + + R + + K ++L+ +++ ++
Sbjct: 932 EIV-LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL 972
Score = 35.4 bits (80), Expect = 0.073
Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 22/185 (11%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
EL + I K K+++ E +L R+T+ E+ LK++ + L+ E + L++
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL---LKAEVQKLQA---- 656
Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQ-EIWDYVKRPNLRLIGVPESDEENGT 172
L +A E+ +M+Q V++ +I+ E+ LQ EI + K +++ +D+
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN--KMEEFKIL----NDQNKAL 710
Query: 173 KLE-NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHII-VRFTKVEMKEKM 230
K E LQ ++ E PN ++++++ Q + T ++ +V KE+
Sbjct: 711 KSEVQKLQTLVSEQ-PN-----KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEE 764
Query: 231 LRAAR 235
L A R
Sbjct: 765 LNAIR 769
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 45.1 bits (105), Expect = 9e-05
Identities = 41/222 (18%), Positives = 102/222 (45%), Gaps = 30/222 (13%)
Query: 30 TEQSWMENDFDELREAGFRRSNYS----ELREDIQTKGKKVENFEKNLEECITRITNTEK 85
TE S + + +L+ + +++ EL++ I K K+++ E+ LE + ++ N EK
Sbjct: 770 TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEK 829
Query: 86 CLKEL-MELKTKAREL------REECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR 138
+++L E+K E+ + + S+ S+ +L+ + E++MN MK + +EK
Sbjct: 830 TVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKD 889
Query: 139 IKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQ 198
+ + LQ++ +E L+ +Q++ Q N + + +
Sbjct: 890 LANTGKWLQDL------------------QEENESLKAHVQEVAQHNLKEASSASQFEEL 931
Query: 199 EIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
EI + ++ + + + R + + K ++L+ +++ ++
Sbjct: 932 EIV-LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL 972
Score = 35.4 bits (80), Expect = 0.073
Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 22/185 (11%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
EL + I K K+++ E +L R+T+ E+ LK++ + L+ E + L++
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL---LKAEVQKLQA---- 656
Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQ-EIWDYVKRPNLRLIGVPESDEENGT 172
L +A E+ +M+Q V++ +I+ E+ LQ EI + K +++ +D+
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN--KMEEFKIL----NDQNKAL 710
Query: 173 KLE-NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHII-VRFTKVEMKEKM 230
K E LQ ++ E PN ++++++ Q + T ++ +V KE+
Sbjct: 711 KSEVQKLQTLVSEQ-PN-----KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEE 764
Query: 231 LRAAR 235
L A R
Sbjct: 765 LNAIR 769
Score = 29.6 bits (65), Expect = 4.0
Identities = 18/93 (19%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 57 EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
E ++++ K +EN + E + EK E T+ REL++ L+ + D
Sbjct: 1190 ERLRSENKDIENLRREREHLEMEL---EKAEMERSTYVTEVRELKDLLTELQKKLDDSYS 1246
Query: 117 RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEI 149
+E+N +K + +++ + Q++
Sbjct: 1247 EAVRQNEELNLLKAQLNETLTKLRTEQNERQKV 1279
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 45.1 bits (105), Expect = 9e-05
Identities = 39/203 (19%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 32 QSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKE-- 89
+ M++ ++LRE E E +Q + +K++ E+ ++E + EK LK+
Sbjct: 440 EEMMQDQEEKLREV---EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 90 -LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
+ E + K E+ + + EE++ E++M E + +E++++ E LQE
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Query: 149 IWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYS 208
+ + + + + + + E+G++ TL I+ Q ++ QE Q + Q+
Sbjct: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPIL---------QVELKSQEAQSLQQQQD 607
Query: 209 SRRATPRHIIVRFTKVEMKEKML 231
R + + + ++ ++ L
Sbjct: 608 HYRGHLQQYVAAYQQLASGKEAL 630
Score = 42.7 bits (99), Expect = 5e-04
Identities = 49/220 (22%), Positives = 102/220 (46%), Gaps = 21/220 (9%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
++RE + + +K+ EK + E +I E+ E+ + K REL E + + +
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEE---EMWRQEEKIRELEEMMQDQEEKLRE 452
Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPE---SDEEN 170
+EE++ E++M E +E++I+R E+ +QE + R +L+ E EE
Sbjct: 453 VEEKMQEEEEKMQE-------QEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEK 504
Query: 171 GTKLENTL---QDIIQENFPNLARQ-ANIQIQEIQ--RMSQRYSSRRATPRHIIVRFTKV 224
+ E + ++ +QE + RQ ++ QE++ + ++ + + + R K+
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564
Query: 225 EMKEKML-RAAREKGRVTLKGKPIRLTADLSAETLQARRE 263
K ++L A RE G L L +L ++ Q+ ++
Sbjct: 565 GQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Score = 38.1 bits (87), Expect = 0.011
Identities = 35/185 (18%), Positives = 88/185 (47%), Gaps = 8/185 (4%)
Query: 57 EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
E + + +K++ E+ + E +I E+ ++ + K E E+ R + + EE
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEE---KMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 117 RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLEN 176
++ E+++ E +++ +E++I+ ++ +QE + + R ++ E +E + E
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
Query: 177 TLQ---DIIQENFPNLARQANIQIQEIQRMSQRYSSR-RATPRHIIVRFTKVEMKEKMLR 232
++ + I+E + RQ +I+E++ M Q + R + K++ +E+ ++
Sbjct: 414 KMREQDEKIREQEEEMWRQEE-KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 233 AAREK 237
EK
Sbjct: 473 RQEEK 477
Score = 37.7 bits (86), Expect = 0.015
Identities = 47/227 (20%), Positives = 94/227 (41%), Gaps = 12/227 (5%)
Query: 20 PPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITR 79
P E + T++ E + + + S SE++ +++ +K+E + L + +
Sbjct: 202 PSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261
Query: 80 ITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEM-----KQEGKV 134
+ ++ KEL + K + EE Q EE++ E+++ E +QE K+
Sbjct: 262 V-EADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKI 320
Query: 135 REKRIK--RNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQ 192
RE+ K R E+ + E + ++ ++ E E K+ + + ++ +
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD 380
Query: 193 ANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGR 239
IQ QE + Q R + R K+ +EK +R EK R
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEK----RQEKMWRQEKKMREQDEKIR 423
Score = 36.6 bits (83), Expect = 0.033
Identities = 40/193 (20%), Positives = 86/193 (44%), Gaps = 21/193 (10%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
E E + + +K+ E+ + E ++ E+ ++E E K RE E+ + +
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE---KIREQEEKMWRQEEKIRE 378
Query: 114 LEERVSAMEDEMNEMKQEGKVRE-------------KRIKRNEQSLQEIWDYVKRPNLRL 160
+E++ E+EM +QE K+RE K+++ ++ ++E + + R ++
Sbjct: 379 QDEKIQEQEEEM--WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
Query: 161 IGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVR 220
+ E ++ KL + + +E ++ IQ QE + Q + R ++ +
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR--QEKLLKQ 494
Query: 221 FTKV-EMKEKMLR 232
K+ E +EKM R
Sbjct: 495 EEKIWEQEEKMWR 507
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 45.1 bits (105), Expect = 9e-05
Identities = 39/203 (19%), Positives = 91/203 (44%), Gaps = 15/203 (7%)
Query: 32 QSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKE-- 89
+ M++ ++LRE E E +Q + +K++ E+ ++E + EK LK+
Sbjct: 440 EEMMQDQEEKLREV---EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496
Query: 90 -LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
+ E + K E+ + + EE++ E++M E + +E++++ E LQE
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556
Query: 149 IWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYS 208
+ + + + + + + E+G++ TL I+ Q ++ QE Q + Q+
Sbjct: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPIL---------QVELKSQEAQSLQQQQD 607
Query: 209 SRRATPRHIIVRFTKVEMKEKML 231
R + + + ++ ++ L
Sbjct: 608 HYRGHLQQYVAAYQQLASGKEAL 630
Score = 42.7 bits (99), Expect = 5e-04
Identities = 49/220 (22%), Positives = 102/220 (46%), Gaps = 21/220 (9%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
++RE + + +K+ EK + E +I E+ E+ + K REL E + + +
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEE---EMWRQEEKIRELEEMMQDQEEKLRE 452
Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPE---SDEEN 170
+EE++ E++M E +E++I+R E+ +QE + R +L+ E EE
Sbjct: 453 VEEKMQEEEEKMQE-------QEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEK 504
Query: 171 GTKLENTL---QDIIQENFPNLARQ-ANIQIQEIQ--RMSQRYSSRRATPRHIIVRFTKV 224
+ E + ++ +QE + RQ ++ QE++ + ++ + + + R K+
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564
Query: 225 EMKEKML-RAAREKGRVTLKGKPIRLTADLSAETLQARRE 263
K ++L A RE G L L +L ++ Q+ ++
Sbjct: 565 GQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604
Score = 38.1 bits (87), Expect = 0.011
Identities = 35/185 (18%), Positives = 88/185 (47%), Gaps = 8/185 (4%)
Query: 57 EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
E + + +K++ E+ + E +I E+ ++ + K E E+ R + + EE
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEE---KMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 117 RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLEN 176
++ E+++ E +++ +E++I+ ++ +QE + + R ++ E +E + E
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
Query: 177 TLQ---DIIQENFPNLARQANIQIQEIQRMSQRYSSR-RATPRHIIVRFTKVEMKEKMLR 232
++ + I+E + RQ +I+E++ M Q + R + K++ +E+ ++
Sbjct: 414 KMREQDEKIREQEEEMWRQEE-KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 233 AAREK 237
EK
Sbjct: 473 RQEEK 477
Score = 36.6 bits (83), Expect = 0.033
Identities = 40/193 (20%), Positives = 86/193 (44%), Gaps = 21/193 (10%)
Query: 54 ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
E E + + +K+ E+ + E ++ E+ ++E E K RE E+ + +
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE---KIREQEEKMWRQEEKIRE 378
Query: 114 LEERVSAMEDEMNEMKQEGKVRE-------------KRIKRNEQSLQEIWDYVKRPNLRL 160
+E++ E+EM +QE K+RE K+++ ++ ++E + + R ++
Sbjct: 379 QDEKIQEQEEEM--WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436
Query: 161 IGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVR 220
+ E ++ KL + + +E ++ IQ QE + Q + R ++ +
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR--QEKLLKQ 494
Query: 221 FTKV-EMKEKMLR 232
K+ E +EKM R
Sbjct: 495 EEKIWEQEEKMWR 507
Score = 36.2 bits (82), Expect = 0.043
Identities = 45/217 (20%), Positives = 91/217 (41%), Gaps = 12/217 (5%)
Query: 30 TEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKE 89
T++ E + + + S SE++ +++ +K+E + L + ++ ++ KE
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270
Query: 90 LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEM-----KQEGKVREKRIK--RN 142
L + K + EE Q EE++ E+++ E +QE K+RE+ K R
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 143 EQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQR 202
E+ + E + ++ ++ E E K+ + + ++ + IQ QE +
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 203 MSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGR 239
Q R + R K+ +EK +R EK R
Sbjct: 391 WRQEEKIREQEEK----RQEKMWRQEKKMREQDEKIR 423
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 44.7 bits (104), Expect = 1e-04
Identities = 62/285 (21%), Positives = 119/285 (41%), Gaps = 32/285 (11%)
Query: 53 SELREDIQTKGKKVENFEKNLEECITRITNTEK----CLKELMELKTKARELREECRSLR 108
S+++ ++++ K+ E EC ++ T + C + + + K R L E +S+
Sbjct: 592 SKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVE 651
Query: 109 SRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDE 168
+ LEE ++ DE+ +++ + V E +K E Q+ + K L++ ES
Sbjct: 652 LKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQM----ESHR 707
Query: 169 ENGTKLENTLQDIIQENFPNL--ARQANIQIQ-EIQRMSQRYSSRRATPRHIIVRFTKVE 225
E + L+D I E + + N ++Q E++++ Y ++ + TK++
Sbjct: 708 EAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHE---KSTKLQ 764
Query: 226 MKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIF------NILKEKNFQPR 279
+ L E+ + LKG + A LQ R +F + K +P
Sbjct: 765 -ELTFLYERHEQSKQDLKG-----LEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPE 818
Query: 280 -----ISYAAKLSFISEG-EIKYFIDKQMLRDFVTTRPALQELLK 318
S K+SF+ E + KQ++RD R L +L K
Sbjct: 819 DSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEK 863
Score = 33.5 bits (75), Expect = 0.28
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 13/96 (13%)
Query: 59 IQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERV 118
I ++ +K+ E NLE+ +T K +L +LR E L R ERV
Sbjct: 823 IHSQKQKISFLENNLEQ----LTKVHK------QLVRDNADLRCELPKLEKRLRATAERV 872
Query: 119 SAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVK 154
A+E + E K EG +++KR R +Q + I + V+
Sbjct: 873 KALEGALKEAK-EGAMKDKR--RYQQEVDRIKEAVR 905
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/200 (20%), Positives = 86/200 (43%), Gaps = 12/200 (6%)
Query: 59 IQTKGKKVENFEKNLEECITRITNTEK--CLKELMELKTKARELREECRSLRSRCDQLEE 116
+Q + + E ++L+E + NT K E+M+ +++ + EEC+SLR + ++
Sbjct: 978 LQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGR 1037
Query: 117 RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLEN 176
++ A E+ + ++K +++ L E + R + + E E +LE
Sbjct: 1038 QLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALREDLERTQKELEK 1097
Query: 177 TLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAARE 236
IQE + L ++ + + Q+M T ++ ++E+++ R+
Sbjct: 1098 ATTK-IQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKY---------LEERLIELLRD 1147
Query: 237 KGRVTLKGKPIRLTADLSAE 256
K + K + LSAE
Sbjct: 1148 KDALWQKSDALEFQQKLSAE 1167
Score = 33.5 bits (75), Expect = 0.28
Identities = 32/177 (18%), Positives = 75/177 (42%), Gaps = 10/177 (5%)
Query: 4 KQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKG 63
+Q T + K P P + + M+ ++L+ R+ E+ +
Sbjct: 376 QQKADTASDTKGRQEPIPSDAAQE-------MQELGEKLQALERERTKVEEVNRQ---QS 425
Query: 64 KKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMED 123
++E K L+ + E+ +KE+ L+ + +E L R +L S+ E+
Sbjct: 426 AQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEE 485
Query: 124 EMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
E+ E+++E K +++ + EQ ++ + ++ +L V + + + + +QD
Sbjct: 486 ELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQD 542
Score = 32.7 bits (73), Expect = 0.47
Identities = 34/173 (19%), Positives = 76/173 (43%), Gaps = 4/173 (2%)
Query: 41 ELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKAREL 100
EL AG + + +Q K E ++ L+E T ++ +E EL+ REL
Sbjct: 563 ELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQE-EELRQANREL 621
Query: 101 REECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRL 160
+E +++ R LE ++ A++ + ++Q + + E I + L
Sbjct: 622 EKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASL 681
Query: 161 IGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQ-RYSSRRA 212
+ V ++ E K + ++ I ++ +Q ++++ Q++++ R+ RA
Sbjct: 682 LAVRKAKE--AMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRA 732
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,420,089
Number of Sequences: 37866
Number of extensions: 549074
Number of successful extensions: 5701
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 608
Number of HSP's that attempted gapping in prelim test: 3317
Number of HSP's gapped (non-prelim): 2336
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.