Search of human proteins with 11641421

Search of human proteins with 11641421

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo
sapiens]
         (350 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo sa...   728   0.0  
gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo sa...   702   0.0  
gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens]         110   1e-24
gi|45007002 longevity assurance homolog 6 [Homo sapiens]              100   2e-21
gi|32455256 LAG1 longevity assurance 2 [Homo sapiens]                  96   4e-20
gi|31077094 LAG1 longevity assurance 2 [Homo sapiens]                  96   4e-20
gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens]           90   3e-18
gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]         87   3e-17
gi|6912450 translocation-associated membrane protein 2 [Homo sap...    42   6e-04
gi|145580602 translocation associated membrane protein 1-like 1 ...    31   1.4  
gi|12545376 chorionic somatomammotropin hormone-like 1 isoform 1...    30   2.5  
gi|239754368 PREDICTED: hypothetical protein [Homo sapiens]            30   4.2  
gi|239748915 PREDICTED: hypothetical protein XP_002346855 [Homo ...    30   4.2  
gi|239742939 PREDICTED: hypothetical protein XP_002342693 [Homo ...    30   4.2  
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre...    30   4.2  
gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu...    30   4.2  
gi|27894385 frizzled 5 precursor [Homo sapiens]                        29   5.5  
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            29   5.5  
gi|7657307 LIM domains containing 1 [Homo sapiens]                     29   5.5  
gi|154146231 DMRT-like family A2 [Homo sapiens]                        29   5.5  
gi|32455271 protein-O-mannosyltransferase 2 [Homo sapiens]             29   7.2  
gi|121949817 DENN/MADD domain containing 2C [Homo sapiens]             29   7.2  
gi|149193323 threonine synthase-like 2 [Homo sapiens]                  29   7.2  
gi|239756274 PREDICTED: hypothetical protein [Homo sapiens]            28   9.4  
gi|239750811 PREDICTED: hypothetical protein XP_002347568 [Homo ...    28   9.4  
gi|239745171 PREDICTED: hypothetical protein XP_002343379 [Homo ...    28   9.4  

>gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo
           sapiens]
          Length = 350

 Score =  728 bits (1880), Expect = 0.0
 Identities = 350/350 (100%), Positives = 350/350 (100%)

Query: 1   MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPEL 60
           MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPEL
Sbjct: 1   MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPEL 60

Query: 61  LLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLL 120
           LLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLL
Sbjct: 61  LLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLL 120

Query: 121 FGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVML 180
           FGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVML
Sbjct: 121 FGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVML 180

Query: 181 LHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAA 240
           LHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAA
Sbjct: 181 LHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAA 240

Query: 241 DLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFL 300
           DLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFL
Sbjct: 241 DLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFL 300

Query: 301 YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLVKDKRF 350
           YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLVKDKRF
Sbjct: 301 YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLVKDKRF 350


>gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo
           sapiens]
          Length = 337

 Score =  702 bits (1812), Expect = 0.0
 Identities = 337/337 (100%), Positives = 337/337 (100%)

Query: 1   MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPEL 60
           MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPEL
Sbjct: 1   MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPEL 60

Query: 61  LLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLL 120
           LLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLL
Sbjct: 61  LLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLL 120

Query: 121 FGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVML 180
           FGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVML
Sbjct: 121 FGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVML 180

Query: 181 LHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAA 240
           LHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAA
Sbjct: 181 LHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAA 240

Query: 241 DLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFL 300
           DLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFL
Sbjct: 241 DLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFL 300

Query: 301 YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAE 337
           YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAE
Sbjct: 301 YIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAE 337


>gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens]
          Length = 394

 Score =  110 bits (276), Expect = 1e-24
 Identities = 92/299 (30%), Positives = 141/299 (47%), Gaps = 22/299 (7%)

Query: 44  LARRGLAEHAHLAPPELLLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESA 103
           L +  L E      P+L LLA        L    T R FR   +R   +P+   K  E++
Sbjct: 84  LEKHFLTEGHRPKEPQLSLLAAQC----GLTLQQTQRWFR--RRRNQDRPQLTKKFCEAS 137

Query: 104 WKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSI 163
           W+FLFYL S+     +L+   + +    P + +D  P   +   +   YLL+  FY  S+
Sbjct: 138 WRFLFYLSSFVGGLSVLYHESWLW---APVMCWDRYPNQTLKPSLYWWYLLELGFY-LSL 193

Query: 164 YATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNI 223
              L  D  RKD    ++HH V +IL+  SY+     +G LVL LHD SD  LE  K+  
Sbjct: 194 LIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLEACKMVN 253

Query: 224 YFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFF 283
           Y +         +    D   L F F +F+ RL  FP ++LY T + S+        Y+F
Sbjct: 254 YMQ---------YQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFFGYYF 304

Query: 284 FNALLLLLTLMNLYWFLYIVAFAAKVL-TGQVHELKDLREYDTAEAQSLKPSKAEKPLR 341
           FN LL+LL L++++W   I+      +  GQ+   KD+R        S + + A++PL+
Sbjct: 305 FNGLLMLLQLLHVFWSCLILRMLYSFMKKGQME--KDIRSDVEESDSSEEAAAAQEPLQ 361


>gi|45007002 longevity assurance homolog 6 [Homo sapiens]
          Length = 384

 Score =  100 bits (249), Expect = 2e-21
 Identities = 84/248 (33%), Positives = 119/248 (47%), Gaps = 19/248 (7%)

Query: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151
           +P    +  ES W+F FYL  ++Y    L  T  P+  +    +Y++ P   +  D+   
Sbjct: 125 KPSTLTRFCESMWRFSFYLYVFTYGVRFLKKT--PWLWNTRHCWYNY-PYQPLTTDLHYY 181

Query: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211
           Y+L+ SFY  S+  + + D  RKD  +M LHH+V++ LI  SY      VG LVL LHD 
Sbjct: 182 YILELSFYW-SLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDS 240

Query: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271
           +D  LE  K+  Y K +            DL  + F   +   RL  FPL VL  T   S
Sbjct: 241 ADALLEAAKMANYAKFQ---------KMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFES 291

Query: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLT-GQVHELKDLR---EYDTAE 327
              V   P ++ FN LLLL+  +N +W   IV  A K ++ G+V   KD R   E  + E
Sbjct: 292 WEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVS--KDDRSDIESSSDE 349

Query: 328 AQSLKPSK 335
             S  P K
Sbjct: 350 EDSEPPGK 357


>gi|32455256 LAG1 longevity assurance 2 [Homo sapiens]
          Length = 380

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 74/256 (28%), Positives = 123/256 (48%), Gaps = 17/256 (6%)

Query: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151
           +P    K  E++W+F FYL   ++ A +    D P+F+D   V+  +     +P      
Sbjct: 126 RPSLLKKFREASWRFTFYL--IAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWY- 182

Query: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211
           Y+++ SFY  S+  ++  D  RKD    ++HHV T+ILI  S+   Y   G L++ LHD 
Sbjct: 183 YMIELSFYW-SLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDS 241

Query: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271
           SD  LE  K+  Y     G  +  + +      + F   +   RL   P  +L+ T    
Sbjct: 242 SDYLLESAKMFNY----AGWKNTCNNI-----FIVFAIVFIITRLVILPFWILHCTLVYP 292

Query: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQV--HELKDLREYDTAEAQ 329
           L   P    Y+FFN+++ +L L++++W   I+  A K +TG++   E  D  E +++E +
Sbjct: 293 LELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGE 352

Query: 330 SLKPSKAEK--PLRNG 343
                   K  PL NG
Sbjct: 353 EAAAGGGAKSRPLANG 368


>gi|31077094 LAG1 longevity assurance 2 [Homo sapiens]
          Length = 380

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 74/256 (28%), Positives = 123/256 (48%), Gaps = 17/256 (6%)

Query: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151
           +P    K  E++W+F FYL   ++ A +    D P+F+D   V+  +     +P      
Sbjct: 126 RPSLLKKFREASWRFTFYL--IAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWY- 182

Query: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211
           Y+++ SFY  S+  ++  D  RKD    ++HHV T+ILI  S+   Y   G L++ LHD 
Sbjct: 183 YMIELSFYW-SLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDS 241

Query: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271
           SD  LE  K+  Y     G  +  + +      + F   +   RL   P  +L+ T    
Sbjct: 242 SDYLLESAKMFNY----AGWKNTCNNI-----FIVFAIVFIITRLVILPFWILHCTLVYP 292

Query: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQV--HELKDLREYDTAEAQ 329
           L   P    Y+FFN+++ +L L++++W   I+  A K +TG++   E  D  E +++E +
Sbjct: 293 LELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGE 352

Query: 330 SLKPSKAEK--PLRNG 343
                   K  PL NG
Sbjct: 353 EAAAGGGAKSRPLANG 368


>gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens]
          Length = 392

 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 68/219 (31%), Positives = 105/219 (47%), Gaps = 13/219 (5%)

Query: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151
           +P    K  ES W+F FYL  + Y    L+ +  P+F D    ++++ P   +   +   
Sbjct: 134 KPPTLTKFCESMWRFTFYLCIFCYGIRFLWSS--PWFWDIRQCWHNY-PFQPLSSGLYHY 190

Query: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211
           Y+++ +FY  S+  + + D  RKD ++M +HH+VT+ LI  SY      VG L++ LHD+
Sbjct: 191 YIMELAFYW-SLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDV 249

Query: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271
           SD  LE  KL  Y K     Y RL     D   + F   +   RL  +P  +L  T   S
Sbjct: 250 SDFLLEAAKLANYAK-----YQRL----CDTLFVIFSAVFMVTRLGIYPFWILNTTLFES 300

Query: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVL 310
              +     ++  N LLL L L+++ W   I   A K L
Sbjct: 301 WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKAL 339


>gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]
          Length = 383

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 69/265 (26%), Positives = 113/265 (42%), Gaps = 32/265 (12%)

Query: 92  QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151
           +P    K  E+ W+F FYL        ++      F +D P ++  W      P+     
Sbjct: 125 RPSRLKKFQEACWRFAFYL--------MITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLP 176

Query: 152 -----YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVL 206
                Y+L+ SFY  S+   L  D  RKD +  ++HH+  + L+  S+   Y   G LV+
Sbjct: 177 SQYWYYILEMSFYW-SLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVM 235

Query: 207 FLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWF--RLYWFPLKVL 264
            +HD++D+ LE  K+  Y                    L F FS  +F  RL  FP  +L
Sbjct: 236 IVHDVADIWLESAKMFSY-----------AGWTQTCNTLFFIFSTIFFISRLIVFPFWIL 284

Query: 265 YATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAK-VLTGQVHELK----D 319
           Y T    +  +     Y F N  L++L +++LYW  YI+    + +    + +++    D
Sbjct: 285 YCTLILPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDED 344

Query: 320 LREYDTAEAQSLKPSKAEKPLRNGL 344
             E +  E +     K    L+NGL
Sbjct: 345 YEEEEEEEEEEATKGKEMDCLKNGL 369


>gi|6912450 translocation-associated membrane protein 2 [Homo
           sapiens]
          Length = 370

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 35/158 (22%), Positives = 71/158 (44%), Gaps = 5/158 (3%)

Query: 52  HAHLAPPELLLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLG 111
           H H  P +L+ +         L +     +   ++KR  L     +K  ES    +F+  
Sbjct: 67  HYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFT 126

Query: 112 SWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDT 171
           S  +  Y++    Y    +P S++ D+ P + +P  +   YL Q +++ H++   LY   
Sbjct: 127 SVIWCFYVVVTEGY--LTNPRSLWEDY-PHVHLPFQVKFFYLCQLAYWLHAL-PELYFQK 182

Query: 172 WRKDSVVMLLHHV-VTLILIVSSYAFRYHNVGILVLFL 208
            RK+ +   L ++ + L+ I  +Y      +G+++L L
Sbjct: 183 VRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLL 220


>gi|145580602 translocation associated membrane protein 1-like 1
           [Homo sapiens]
          Length = 369

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 23/112 (20%), Positives = 50/112 (44%), Gaps = 3/112 (2%)

Query: 98  KMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGS 157
           K  ES    +FY  S  +  ++L   +       P++ +   P   +   +   Y+ Q +
Sbjct: 118 KFNESGQFSVFYFFSCIWGTFILISENCL---SDPTLIWKARPHSMMTFQMKFFYISQLA 174

Query: 158 FYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLH 209
           ++ H+     +  T ++D    L++  + L  I  +Y    +++G+L+L LH
Sbjct: 175 YWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLH 226


>gi|12545376 chorionic somatomammotropin hormone-like 1 isoform 1
           precursor [Homo sapiens]
          Length = 222

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 41/179 (22%), Positives = 62/179 (34%), Gaps = 40/179 (22%)

Query: 60  LLLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYL 119
           LL  AL  L W     A        L K   LQ   A ++    ++   ++ SW   AY+
Sbjct: 10  LLAFALLCLPWLQEAGAVQTVPLSRLFKEAMLQAHRAHQLAIDTYQE--FISSWGMEAYI 67

Query: 120 LFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVM 179
                Y F HD  + F                       +  SI  +  M+  ++ S + 
Sbjct: 68  TKEQKYSFLHDSQTSF----------------------CFSDSIPTSSNMEETQQKSNLE 105

Query: 180 LLHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHAL 238
           LLH  ++L+LI S               L  +  ++  FT   +Y  S    YH L  L
Sbjct: 106 LLH--ISLLLIESR--------------LEPVRFLRSTFTNNLVYDTSDSDDYHLLKDL 148


>gi|239754368 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 336

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 2   AAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLA 45
           A   P AGP  P P P  A+  +  W +A    RGC    WG A
Sbjct: 97  ADVSPPAGPV-PAPTPPRARNAETPWNAASLLNRGCC---WGAA 136


>gi|239748915 PREDICTED: hypothetical protein XP_002346855 [Homo
           sapiens]
          Length = 336

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 2   AAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLA 45
           A   P AGP  P P P  A+  +  W +A    RGC    WG A
Sbjct: 97  ADVSPPAGPV-PAPTPPRARNAETPWNAASLLNRGCC---WGAA 136


>gi|239742939 PREDICTED: hypothetical protein XP_002342693 [Homo
           sapiens]
          Length = 321

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 2   AAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLA 45
           A   P AGP  P P P  A+  +  W +A    RGC    WG A
Sbjct: 97  ADVSPPAGPV-PAPTPPRARNAETPWNAASLLNRGCC---WGAA 136


>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
           precursor [Homo sapiens]
          Length = 452

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 297 YWFLYIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLV 345
           +W  Y+  FAA V     H   D R+   A+ +  +P +AE  +RN +V
Sbjct: 314 FWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSRP-RAEMDVRNAIV 361


>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
          precursor [Homo sapiens]
          Length = 304

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 13/31 (41%), Positives = 15/31 (48%), Gaps = 1/31 (3%)

Query: 10 PTGPEPMPSYAQLVQRGWGSALAAARGCTDC 40
          PTG  P P     ++RGW   LA   GC  C
Sbjct: 27 PTGARPSPG-PDYLRRGWMRLLAEGEGCAPC 56


>gi|27894385 frizzled 5 precursor [Homo sapiens]
          Length = 585

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 3/80 (3%)

Query: 19  YAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPELLLLALGALGWTALRSAAT 78
           Y Q  +  W +AL  A    D G   A+    E+  L     + L +G      + S  T
Sbjct: 470 YEQHYRESWEAALTCACPGHDTGQPRAK---PEYWVLMLKYFMCLVVGITSGVWIWSGKT 526

Query: 79  ARLFRPLAKRCCLQPRDAAK 98
              +R    RCC +PR   K
Sbjct: 527 VESWRRFTSRCCCRPRRGHK 546


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 12/75 (16%)

Query: 36  GCTDCGWGLARRGLAEHAHLAPPELLLLAL--------GALGWTALRSAATARLFRPLAK 87
           GC  CG G  R     HA LA  ELL L L         A GW  L+         P A+
Sbjct: 529 GCPHCGLGGHRAHFLPHAGLAGTELLPLRLLAQLAPQGCAEGWLVLQGEGEG----PQAQ 584

Query: 88  RCCLQPRDAAKMPES 102
               + R+ ++ PE+
Sbjct: 585 GPLREGREVSQAPET 599


>gi|7657307 LIM domains containing 1 [Homo sapiens]
          Length = 676

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 10/103 (9%)

Query: 1   MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWG--LARRGLAEHAHLAPP 58
           ++++ P++ P G +         Q+G    L    GCTD G G  L+   L        P
Sbjct: 345 LSSSAPSSSPAGLDGS-------QQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLP 397

Query: 59  ELLLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPE 101
           EL     G LGW++  S  +  L  P + R  L  +     PE
Sbjct: 398 ELSCKE-GPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPE 439


>gi|154146231 DMRT-like family A2 [Homo sapiens]
          Length = 542

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 44/177 (24%), Positives = 60/177 (33%), Gaps = 13/177 (7%)

Query: 2   AAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPELL 61
           A  GPAA P   +     A      W S + AA        G       +    APP   
Sbjct: 360 AGLGPAAPPD--KAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHR 417

Query: 62  LLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESA-----WKFLFYLGSWSYS 116
            L  GA+   AL S ++   F PL         DA   P  A        L Y  + ++S
Sbjct: 418 PLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHS 477

Query: 117 AYLLFGTDY------PFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATL 167
             L F   Y      P     P + Y ++  M      AAA + +   YG  +Y  +
Sbjct: 478 RGLAFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSAAAAAAVHKEPTYGGGLYGPM 534


>gi|32455271 protein-O-mannosyltransferase 2 [Homo sapiens]
          Length = 750

 Score = 28.9 bits (63), Expect = 7.2
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 13/76 (17%)

Query: 40  CGWGLARRGLAEHAHLAPPELLLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKM 99
           C WGLA   LA   H+A   +L L LG        +A +  LF PLA          A+ 
Sbjct: 688 CAWGLASWPLARGIHVA--GILSLLLG--------TAYSFYLFHPLAYG---MVGPLAQD 734

Query: 100 PESAWKFLFYLGSWSY 115
           P+S    L +L SW +
Sbjct: 735 PQSPMAGLRWLDSWDF 750


>gi|121949817 DENN/MADD domain containing 2C [Homo sapiens]
          Length = 871

 Score = 28.9 bits (63), Expect = 7.2
 Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 5/58 (8%)

Query: 160 GHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLE 217
           GH++ ATLY  TW+   + +L   ++ ++   + +      +GIL   L  + D+ +E
Sbjct: 651 GHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFL-----IGILSCSLPQLQDLPIE 703


>gi|149193323 threonine synthase-like 2 [Homo sapiens]
          Length = 484

 Score = 28.9 bits (63), Expect = 7.2
 Identities = 11/20 (55%), Positives = 13/20 (65%)

Query: 83  RPLAKRCCLQPRDAAKMPES 102
           +P   RCCL P  AAK PE+
Sbjct: 408 QPSTPRCCLAPASAAKFPEA 427


>gi|239756274 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 775

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 31/86 (36%), Positives = 33/86 (38%), Gaps = 11/86 (12%)

Query: 28  GSALAAARGCT-DCGWGLARRGLAEHAHLAPPELLLLALGALGWTALRSAATARLFRPLA 86
           GSA AAA G   D GW          A  AP   LL   GA        AA  RL   L 
Sbjct: 681 GSAAAAAVGNPGDYGW----------AATAPRTRLLSNPGAASGLVPVYAAPRRLGLRLL 730

Query: 87  KRCCLQPRDAAKMPESAWKFLFYLGS 112
             C    R AA    +   FL Y+GS
Sbjct: 731 ASCSRPARSAATETCALGAFLIYIGS 756


>gi|239750811 PREDICTED: hypothetical protein XP_002347568 [Homo
           sapiens]
          Length = 765

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 31/86 (36%), Positives = 33/86 (38%), Gaps = 11/86 (12%)

Query: 28  GSALAAARGCT-DCGWGLARRGLAEHAHLAPPELLLLALGALGWTALRSAATARLFRPLA 86
           GSA AAA G   D GW          A  AP   LL   GA        AA  RL   L 
Sbjct: 671 GSAAAAAVGNPGDYGW----------AATAPRTRLLSNPGAASGLVPVYAAPRRLGLRLL 720

Query: 87  KRCCLQPRDAAKMPESAWKFLFYLGS 112
             C    R AA    +   FL Y+GS
Sbjct: 721 ASCSRPARSAATETCALGAFLIYIGS 746


>gi|239745171 PREDICTED: hypothetical protein XP_002343379 [Homo
           sapiens]
          Length = 765

 Score = 28.5 bits (62), Expect = 9.4
 Identities = 31/86 (36%), Positives = 33/86 (38%), Gaps = 11/86 (12%)

Query: 28  GSALAAARGCT-DCGWGLARRGLAEHAHLAPPELLLLALGALGWTALRSAATARLFRPLA 86
           GSA AAA G   D GW          A  AP   LL   GA        AA  RL   L 
Sbjct: 671 GSAAAAAVGNPGDYGW----------AATAPRTRLLSNPGAASGLVPVYAAPRRLGLRLL 720

Query: 87  KRCCLQPRDAAKMPESAWKFLFYLGS 112
             C    R AA    +   FL Y+GS
Sbjct: 721 ASCSRPARSAATETCALGAFLIYIGS 746


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.464 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,730,432
Number of Sequences: 37866
Number of extensions: 594947
Number of successful extensions: 2326
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2297
Number of HSP's gapped (non-prelim): 34
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.