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Search of human proteins with 116295258
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116295258 integrin alpha 2 precursor [Homo sapiens]
(1181 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 2354 0.0
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 840 0.0
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 707 0.0
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 659 0.0
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 375 e-103
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 373 e-103
gi|34452173 integrin alpha X precursor [Homo sapiens] 371 e-102
gi|62548866 integrin, alpha D precursor [Homo sapiens] 340 5e-93
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 333 8e-91
gi|148728188 integrin, alpha E precursor [Homo sapiens] 300 7e-81
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 288 3e-77
gi|49170034 integrin, alpha 8 [Homo sapiens] 223 6e-58
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 216 1e-55
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 204 4e-52
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 204 4e-52
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 203 7e-52
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 201 4e-51
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 199 1e-50
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 199 1e-50
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 189 1e-47
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 171 3e-42
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 169 2e-41
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 168 2e-41
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 149 2e-35
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 145 2e-34
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 145 2e-34
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 90 1e-17
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 86 2e-16
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 80 1e-14
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 80 1e-14
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 2354 bits (6100), Expect = 0.0
Identities = 1181/1181 (100%), Positives = 1181/1181 (100%)
Query: 1 MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKG 60
MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKG
Sbjct: 1 MGPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKG 60
Query: 61 NWLLVGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILT 120
NWLLVGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILT
Sbjct: 61 NWLLVGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILT 120
Query: 121 RNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCD 180
RNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCD
Sbjct: 121 RNMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCD 180
Query: 181 ESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATS 240
ESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATS
Sbjct: 181 ESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATS 240
Query: 241 QTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCN 300
QTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCN
Sbjct: 241 QTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCN 300
Query: 301 HDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQ 360
HDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQ
Sbjct: 301 HDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQ 360
Query: 361 IFSIEGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFP 420
IFSIEGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFP
Sbjct: 361 IFSIEGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFP 420
Query: 421 KQAFDQILQDRNHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQ 480
KQAFDQILQDRNHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQ
Sbjct: 421 KQAFDQILQDRNHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQ 480
Query: 481 AHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQH 540
AHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQH
Sbjct: 481 AHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQH 540
Query: 541 QFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKY 600
QFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKY
Sbjct: 541 QFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKY 600
Query: 601 SQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEAS 660
SQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEAS
Sbjct: 601 SQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEAS 660
Query: 661 FTPEKITLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKEN 720
FTPEKITLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKEN
Sbjct: 661 FTPEKITLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKEN 720
Query: 721 NERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTSPALEAYSETAKV 780
NERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTSPALEAYSETAKV
Sbjct: 721 NERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTSPALEAYSETAKV 780
Query: 781 FSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTG 840
FSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTG
Sbjct: 781 FSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTG 840
Query: 841 IVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTINFDFNLQ 900
IVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTINFDFNLQ
Sbjct: 841 IVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTINFDFNLQ 900
Query: 901 NLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSI 960
NLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSI
Sbjct: 901 NLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSI 960
Query: 961 VHSFEDVGPKFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCN 1020
VHSFEDVGPKFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCN
Sbjct: 961 VHSFEDVGPKFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCN 1020
Query: 1021 ADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIW 1080
ADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIW
Sbjct: 1021 ADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIW 1080
Query: 1081 NGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSII 1140
NGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSII
Sbjct: 1081 NGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSII 1140
Query: 1141 AGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTELSS 1181
AGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTELSS
Sbjct: 1141 AGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTELSS 1181
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 840 bits (2171), Expect = 0.0
Identities = 476/1182 (40%), Positives = 697/1182 (58%), Gaps = 67/1182 (5%)
Query: 23 ILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYK 82
+L CC+++NV + + FSGP + FGY VQQ+ N +G W+L+GSP G P+NR GDVYK
Sbjct: 22 VLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYK 81
Query: 83 CPVDLSTAT-CEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGN 141
CPV + C KL+L +TSIPNVTE+K NM+ G L N GGFL CGPL+A +CG+
Sbjct: 82 CPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPN-GGFLACGPLYAYRCGH 140
Query: 142 QYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQG 201
+YTTG+CSD+SP FQ+ S +P Q C + +D+V+V D SNSIYPWD+V FL ++
Sbjct: 141 LHYTTGICSDVSPTFQVVNSIAPV-QECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLER 199
Query: 202 LDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARK 261
+DIGP +TQVG++QY N FNLN Y + EE++VA + Q GG T T I ARK
Sbjct: 200 MDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARK 259
Query: 262 YAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALD 321
A++ A G RR KVMV+VTDGESHD LK VI C +NI RF IA+LG NR L
Sbjct: 260 EAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLS 319
Query: 322 TKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV-QGGDNFQMEMSQ 380
T+ ++EIK+IAS PTE++FFNVSDE AL+ TLGE+IF++E T Q +F+MEMSQ
Sbjct: 320 TEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQ 379
Query: 381 VGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNH---SSYL 437
GFSA YS D +MLGAVGA+ W+GT+V + + +I P+ + + + +SYL
Sbjct: 380 TGFSAHYS--QDWVMLGAVGAYDWNGTVVMQKA-SQIIIPRNTTFNVESTKKNEPLASYL 436
Query: 438 GYSV-AAISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQIGSYFGSVLC 496
GY+V +A ++ ++AG PR N+TGQ+++Y + E+GNI ++Q G+QIGSYFGS+L
Sbjct: 437 GYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILT 495
Query: 497 SVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFLEGPE--------- 547
+ D+DKD+ TD+LLVGAPMYM K+E+G+VY++ + + LE +
Sbjct: 496 TTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQH 555
Query: 548 ---GIEN------TRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRT 598
EN RFG+AIAA+ D+N+DGFND+++G+PLE+ + GAVYIY+G TIR
Sbjct: 556 NSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRK 615
Query: 599 KYSQKI-LGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAI 657
+Y+Q+I G DG L++FG+S+ G DLNGD +TDV+IG G WS+ +A V +
Sbjct: 616 EYAQRIPSGGDG---KTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKV 672
Query: 658 EASFTPEKITLVNKNAQ--------IILKLCFSAKFRPTKQN-NQVAIVYNITLDADGFS 708
+F P K+ + KN I +CF K + + + + Y +TLD S
Sbjct: 673 TMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLD----S 728
Query: 709 SRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTS 768
R SR F ER +Q+N+ V +++ C +H Y+ + D +S+ + +D +L +P
Sbjct: 729 LRQISRSFFSGTQERKVQRNITVRKSE-CTKHSFYMLDKHDFQDSVRITLDFNLTDPENG 787
Query: 769 PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVT 828
P L+ + IPF KDCG CISDL L + ++ IV +QN + S+T
Sbjct: 788 PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSL---HVATTEKDLLIVRSQNDKFNVSLT 844
Query: 829 LKNKRESAYNTGIVVDFSENLFFASF-SLPVDGTEVTCQVAASQKSVACDVGYPALKREQ 887
+KN ++SAYNT +V +S NL F+ ++ D E S ++ C VGYP L+R +
Sbjct: 845 VKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCE-------SNHNITCKVGYPFLRRGE 897
Query: 888 QVTFTINFDFNLQNLQNQASLSFQALSESQE--ENKADNLVNLKIPLLYDAEIHLTRSTN 945
VTF I F FN L ++ A S+S+E E +DN+VN+ IP+ Y+ + S +
Sbjct: 898 MVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSAS 957
Query: 946 INFYEISSDGNVPSIVHSFEDVGPKF-IFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLM 1004
I+++ VP +++S ED+G + IF L +GS P+ + I P T P++
Sbjct: 958 EYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVL 1017
Query: 1005 YLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKD 1064
Y TG+ + + + + +P I + ++ +++ + L+C T + +TC L
Sbjct: 1018 YPTGLSSSENANCRPHIFEDPFSI-NSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTS 1076
Query: 1065 VHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTV-TIPLMIMK 1123
+ VNV+ +W TF S F ++ LT E+ + N + + N + + I K
Sbjct: 1077 SDISQ---VNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISK 1133
Query: 1124 PDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRKYEK 1165
VP VI+ S AG+LLL+ L+ LWK+GFFKR +K
Sbjct: 1134 DGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKK 1175
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 707 bits (1824), Expect = 0.0
Identities = 425/1176 (36%), Positives = 668/1176 (56%), Gaps = 73/1176 (6%)
Query: 30 YNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLST 89
+N+ + ++ G + FGY VQQ WL+VG+P + GDVYKCPV
Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPV--IH 80
Query: 90 ATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGVC 149
C KLNL T + NV+E K NM LGL L N FL C PLW+ +CG+ YYTTG+C
Sbjct: 81 GNCTKLNLGRVT-LSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMC 139
Query: 150 SDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKT 209
S ++ +F+ S + +PA Q C + +D+V+V D SNSIYPW V++FL ++ IGP +
Sbjct: 140 SRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVEVQHFLINILKKFYIGPGQI 199
Query: 210 QVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASG 269
QVG++QY + F+LN Y++ ++++ A S Q GG T T I++AR A+ G
Sbjct: 200 QVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--KG 257
Query: 270 GRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEI 329
GR+ A KVM+V+TDGESHD L+ VI Q DN+ R+ +AVLGY NR ++ + + EI
Sbjct: 258 GRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEI 317
Query: 330 KAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMSQVGFSADYSS 389
K IAS P +++FFNV+DEAAL + LG++IFS+EGT + +F +EMSQ GFS+
Sbjct: 318 KYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHV-- 375
Query: 390 QNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQD--RNHSSYLGYSV-AAIST 446
D ++LGAVGA+ W+G ++++TS G +I ++++ + + +NH +YLGY+V + +S+
Sbjct: 376 VEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSS 435
Query: 447 GESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTIT 506
+ +VAGAPR N+TG+++L++++ N ++T+ QA RG QIGSYFGS + SVD+D D +T
Sbjct: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
Query: 507 DVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFLEGPEGIENTRFGSAIAALSDINM 566
DVLLVGAPMY ++ +E G+VY++ +++ + + L+ +N RFGS+IA++ D+N
Sbjct: 496 DVLLVGAPMYFNE-GRERGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQ 554
Query: 567 DGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYG 626
D +NDV+VG+PLE+ ++GA+YI++G +G+I Q+I S+ A + LQYFG S+ G
Sbjct: 555 DSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELA--TGLQYFGCSIHGQL 612
Query: 627 DLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKITLVNKNAQ--------IILK 678
DLN D + D+++GA G V LWS+ + + F P KI + +++ + +
Sbjct: 613 DLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAF 672
Query: 679 LCFSAKF-RPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSC 737
LCF+ F P Q V I YN T+D R T R E +R + ++++ Q
Sbjct: 673 LCFTPIFLAPHFQTTTVGIRYNATMD----ERRYTPRAHLDEGGDRFTNRAVLLSSGQEL 728
Query: 738 PEHI-IYIQEPSDVVNSLDLRVDISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCI 796
E I ++ + +D V + V+ SLE+P P L+ T S+PF C ED C+
Sbjct: 729 CERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCV 788
Query: 797 SDLVLDVR-QIPAAQE----------------------QPFIVSNQNKRLTFSVTLKNKR 833
DLVLD R +P A E FI+ + +R+ TL+N+
Sbjct: 789 PDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRG 848
Query: 834 ESAYNTGIVVDFSENLFFASFSLPVD---GTEVTCQVAASQKSVACDVGYPALKREQQVT 890
E+AY+T + + S NL FAS D E + QK V C+V YP + + +V
Sbjct: 849 ENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQV-CNVSYPFFRAKAKVA 907
Query: 891 FTINFDFNLQNLQNQASLSFQALSESQEEN--KADNLVNLKIPLLYDAEIHLTRSTNINF 948
F ++F+F+ + + A S+S E + K DN+ L+ L Y+A++ TRS++++
Sbjct: 908 FRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSSSLSH 967
Query: 949 YEISSDGNVPSIVHSFEDVGPKF--IFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYL 1006
YE+ + S + ++ +GP F IF ++ G P+ + I IP T+ N L+ L
Sbjct: 968 YEVKPN----SSLERYDGIGPPFSCIFRIQ-NLGLFPIHGMMMKITIPIATRSGNRLLKL 1022
Query: 1007 TGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVH 1066
TD+A + SCN N + T E+ R +LN + ++ C ++ V
Sbjct: 1023 RDFLTDEA-NTSCNIWGNSTEYRPTP-----VEEDLRRAPQLNHSNSDVVSINCNIRLVP 1076
Query: 1067 MKGEYFVNVTTRIWNGTFASSTFQT--VQLTAAAEINTYNPEIYVIEDNTVTIPLMIMKP 1124
+ E ++ +W + + +++ + + AA + ++P I+ ED + I I K
Sbjct: 1077 NQ-EINFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISK- 1134
Query: 1125 DEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFK 1160
E +VP +I+GS + G+LLL LV LWKLGFF+
Sbjct: 1135 QEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 659 bits (1699), Expect = 0.0
Identities = 407/1179 (34%), Positives = 633/1179 (53%), Gaps = 63/1179 (5%)
Query: 11 LPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWS 70
LPL+ + L C +N+ ++F GP +FGY+V Q + W+LVG+PW
Sbjct: 11 LPLVFLTGL-------CSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWD 63
Query: 71 GFPENRMGDVYKCPVD-LSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFL 129
G +R GDVY+CPV A C K +L + N + NM LG+ L G GGF+
Sbjct: 64 GPSGDRRGDVYRCPVGGAHNAPCAKGHLG-DYQLGNSSHPAVNMHLGMSLLETDGDGGFM 122
Query: 130 TCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWD 189
C PLW++ CG+ +++G+C+ + FQ S +P Q CP+ +DVV+V D SNSIYPW
Sbjct: 123 ACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWS 182
Query: 190 AVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDL 249
V+ FL + V L I P + QVGL+QY +P ++L ++TKEE++ A S+ G
Sbjct: 183 EVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRE 242
Query: 250 TNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGI 309
T T AI A +S + GGR A +++VVVTDGESHDG L A + C + R+GI
Sbjct: 243 TKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGI 302
Query: 310 AVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGT-V 368
AVLG+ R D + ++EI+ IAS P ER+FFNV+DEAAL + LG++IF +EG+
Sbjct: 303 AVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHA 362
Query: 369 QGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFP-----KQA 423
+ +F +EMSQ+GFS D ++ G VGA+ W G+++ GH +FP +
Sbjct: 363 ENESSFGLEMSQIGFST--HRLKDGILFGMVGAYDWGGSVLW-LEGGHRLFPPRMALEDE 419
Query: 424 FDQILQDRNHSSYLGYSVAA-ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAH 482
F LQ NH++YLGYSV++ + G F++GAPR + G+++ + + ++G + V Q+
Sbjct: 420 FPPALQ--NHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSL 477
Query: 483 RGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQF 542
+G+QIGSYFGS LC +D D+D TDVLLV APM++ KE GRVY++ + + L Q
Sbjct: 478 QGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQG 537
Query: 543 LEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQ 602
PE ++ RFG A+ AL D+N DGF DV VG+PLE+ + GA+Y+Y+G Q +R +Q
Sbjct: 538 TLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQ 597
Query: 603 KILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFT 662
+I + + L YFGRS+DG DL+GD + DV++GA G + L S+ I + T
Sbjct: 598 RIAAA--SMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVT 655
Query: 663 PEKITLVNKNAQ--------IILKLCFSAKFR-PTKQNNQVAIVYNITLDADGFSSRVTS 713
P+ I++V ++ + + LCF R P + ++Q + + +LD +
Sbjct: 656 PQAISVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLD----EWTAGA 711
Query: 714 RGLFKENNERCLQKNMVVNQAQ-SCPEHIIYIQEPSDVVNSLDLRVDISLEN---PGTSP 769
R F + +R + + ++ +C + ++ + SD + + L V +L+N PG P
Sbjct: 712 RAAFDGSGQRLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPG--P 769
Query: 770 ALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVR-QIPAAQEQPFIVSNQNKRLTFSVT 828
L S T+ +PF KDCG D C++DLVL V I +++ PF+V +++ S T
Sbjct: 770 VLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTT 829
Query: 829 LKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAA-SQKSVACDVGYPALKREQ 887
L+N++E+AYNT + + FS NL AS + P + + + AA S + C VG+P +
Sbjct: 830 LENRKENAYNTSLSLIFSRNLHLASLT-PQRESPIKVECAAPSAHARLCSVGHPVFQTGA 888
Query: 888 QVTFTINFDFNLQNLQNQASLSFQALSESQEENKA--DNLVNLKIPLLYDAEIHLTRSTN 945
+VTF + F+F+ +L +Q + A S+S E N DN + Y+ + + +
Sbjct: 889 KVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSEST 948
Query: 946 INFYEISSDGNVPSIVHSFEDVGPKFIFSLKV-TTGSVPVSMATVIIHIPQYTKEKNPLM 1004
++ YE+ G +P GP+F +L+V G VS + +P N +
Sbjct: 949 LHRYEVHPYGTLP------VGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFL 1002
Query: 1005 YLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKD 1064
L+ V T+ A I N P E +HT LN C V C L
Sbjct: 1003 SLSQVITNNASCIVQNLTEPP--------GPPVHPEELQHTNRLNGSNTQCQVVRCHLGQ 1054
Query: 1065 VHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEI-YVIEDNTVTIPLMIMK 1123
+ E V + + N F + F+++ + + E+ T + + E + + L+ +
Sbjct: 1055 LAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVV 1114
Query: 1124 PDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRK 1162
+ ++IGS++ G+LLL LV LWKLGFF K
Sbjct: 1115 QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHK 1153
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 375 bits (964), Expect = e-103
Identities = 335/1201 (27%), Positives = 543/1201 (45%), Gaps = 128/1201 (10%)
Query: 24 LNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKC 83
L C +N+ A F ++ FG +V Q +G+ ++VG+P N+ G +Y+C
Sbjct: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSVVQL---QGSRVVVGAPQEIVAANQRGSLYQC 66
Query: 84 PVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQY 143
D ST +CE + LQ NMSLGL L L CGP Q C
Sbjct: 67 --DYSTGSCEPIRLQVPVEA-------VNMSLGLSLAATTSPPQLLACGPTVHQTCSENT 117
Query: 144 YTTGVCSDISPDF-QLSASFSPATQPCPSL-IDVVVVCDESNSIYPWD--AVKNFLEKFV 199
Y G+C + Q F A + CP D+ + D S SI P D +K F+ +
Sbjct: 118 YVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVM 177
Query: 200 QGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYA 259
+ L +KT L+QY+ R+ F ++ +Q G T+T I+
Sbjct: 178 EQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKV 234
Query: 260 RKYAYSAASGGRRSATKVMVVVTDGESHDGSM-LKAVIDQCNHDNILRFGIAVLGYLNRN 318
+ ++ +G R++A K++VV+TDGE + + VI + + + ++R+ I V +
Sbjct: 235 VRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGV-----GD 289
Query: 319 ALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDN-FQME 377
A ++ +E+ IAS P + F V++ AL L E+IF+IEGT G + F+ E
Sbjct: 290 AFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHE 349
Query: 378 MSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNHSSYL 437
MSQ GFSA +S +L VG++ W+G + TS F ++ D N +YL
Sbjct: 350 MSQEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINMT--RVDSDMN-DAYL 404
Query: 438 GYSVAAISTGESTHFVAGAPRANYTGQIVLYSVN-----ENGNITVIQAHRGDQIGSYFG 492
GY+ A I V GAPR + G + ++ N N N+ +G QIG+YFG
Sbjct: 405 GYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV------KGTQIGAYFG 458
Query: 493 SVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQ---FLEGPEGI 549
+ LCSVDVD + TD++L+GAP Y + G+V + + G + Q L G +G
Sbjct: 459 ASLCSVDVDSNGSTDLVLIGAPHYYEQTRG--GQVSVCPLPRGQRARWQCDAVLYGEQGQ 516
Query: 550 ENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGT-IRTKYSQKILGSD 608
RFG+A+ L D+N D DV +G+P E N GAVY+++G G+ I +SQ+I GS
Sbjct: 517 PWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSK 576
Query: 609 GAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKIT- 667
+ R LQYFG+SL G DL D + D+++GA G V+ L SQ + V F P ++
Sbjct: 577 LSPR--LQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVAR 634
Query: 668 -LVNKNAQII-------LKLCF----SAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRG 715
+ N Q++ +++C S + R + Q + Y++ LD S R SR
Sbjct: 635 NVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALD----SGRPHSRA 690
Query: 716 LFKENNERCLQKNMVVNQAQSCPEHIIYIQEPS---DVVNSLDLRVDISLENPGTS---- 768
+F E ++ V+ Q+C + +Q P+ D V+ + LR++ SL S
Sbjct: 691 VFNETKNSTRRQTQVLGLTQTC--ETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGN 748
Query: 769 --PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFS 826
P L ++ PF K+CG D +C DL + + +V + +
Sbjct: 749 LRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF----SFMSLDCLVVGGPREFNVT 804
Query: 827 VTLKNKRESAYNTGIVVDFSENLFFA------------SFSLPVDGTEVTCQVAASQKSV 874
VT++N E +Y T + F +L + S+ L + T +V+ + KS
Sbjct: 805 VTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASST-EVSGALKST 863
Query: 875 ACDVGYPALKREQQVTFTINFDFNLQ-NLQNQASLSFQALSESQEENKADNLVNLKIPLL 933
+C + +P +VTF I FD + + +L N+ L SE+ L++P+
Sbjct: 864 SCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVK 923
Query: 934 YDAEI----HLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVT-TGSVPVSM-A 987
Y + H + +NF + V + ++G + SL ++ VPV +
Sbjct: 924 YAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQR---SLPISLVFLVPVRLNQ 980
Query: 988 TVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKE 1047
TVI PQ T +N +C+ + S F +E R
Sbjct: 981 TVIWDRPQVTFSENL-------------SSTCHTK------ERLPSHSDFLAE-LRKAPV 1020
Query: 1048 LNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEI 1107
+NC A C + C + ++ E+ + + + ++ + + + AEI +
Sbjct: 1021 VNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVF 1080
Query: 1108 YVIEDNTVTIPLMIMKPDEKAEVPTGV--IIGSIIAGILLLLALVAILWKLGFFKRKYEK 1165
++ + E EVP + I+GS + G+LLL + A L+KLGFFKR+Y+
Sbjct: 1081 TLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKD 1140
Query: 1166 M 1166
M
Sbjct: 1141 M 1141
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 373 bits (957), Expect = e-103
Identities = 334/1200 (27%), Positives = 541/1200 (45%), Gaps = 127/1200 (10%)
Query: 24 LNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKC 83
L C +N+ A F ++ FG +V Q +G+ ++VG+P N+ G +Y+C
Sbjct: 11 LTLCHGFNLDTENAMTFQ-ENARGFGQSVVQL---QGSRVVVGAPQEIVAANQRGSLYQC 66
Query: 84 PVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQY 143
D ST +CE + LQ NMSLGL L L CGP Q C
Sbjct: 67 --DYSTGSCEPIRLQVPVEA-------VNMSLGLSLAATTSPPQLLACGPTVHQTCSENT 117
Query: 144 YTTGVCSDISPDF-QLSASFSPATQPCPSL-IDVVVVCDESNSIYPWD--AVKNFLEKFV 199
Y G+C + Q F A + CP D+ + D S SI P D +K F+ +
Sbjct: 118 YVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVM 177
Query: 200 QGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYA 259
+ L +KT L+QY+ R+ F ++ +Q G T+T I+
Sbjct: 178 EQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKV 234
Query: 260 RKYAYSAASGGRRSATKVMVVVTDGESHDGSM-LKAVIDQCNHDNILRFGIAVLGYLNRN 318
+ ++ +G R++A K++VV+TDGE + + VI + + + ++R+ I V +
Sbjct: 235 VRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGV-----GD 289
Query: 319 ALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTVQGGDN-FQME 377
A ++ +E+ IAS P + F V++ AL L E+IF+IEGT G + F+ E
Sbjct: 290 AFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHE 349
Query: 378 MSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNHSSYL 437
MSQ GFSA +S +L VG++ W+G + TS F ++ D N +YL
Sbjct: 350 MSQEGFSAAITSNGPLL--STVGSYDWAGGVFLYTSKEKSTFINMT--RVDSDMN-DAYL 404
Query: 438 GYSVAAISTGESTHFVAGAPRANYTGQIVLYSVN-----ENGNITVIQAHRGDQIGSYFG 492
GY+ A I V GAPR + G + ++ N N N+ +G QIG+YFG
Sbjct: 405 GYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANV------KGTQIGAYFG 458
Query: 493 SVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQH--QFLEGPEGIE 550
+ LCSVDVD + TD++L+GAP Y + G+V + + G L G +G
Sbjct: 459 ASLCSVDVDSNGSTDLVLIGAPHYYEQTRG--GQVSVCPLPRGRARWQCDAVLYGEQGQP 516
Query: 551 NTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGT-IRTKYSQKILGSDG 609
RFG+A+ L D+N D DV +G+P E N GAVY+++G G+ I +SQ+I GS
Sbjct: 517 WGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKL 576
Query: 610 AFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKIT-- 667
+ R LQYFG+SL G DL D + D+++GA G V+ L SQ + V F P ++
Sbjct: 577 SPR--LQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARN 634
Query: 668 LVNKNAQII-------LKLCF----SAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGL 716
+ N Q++ +++C S + R + Q + Y++ LD S R SR +
Sbjct: 635 VFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALD----SGRPHSRAV 690
Query: 717 FKENNERCLQKNMVVNQAQSCPEHIIYIQEPS---DVVNSLDLRVDISLENPGTS----- 768
F E ++ V+ Q+C + +Q P+ D V+ + LR++ SL S
Sbjct: 691 FNETKNSTRRQTQVLGLTQTC--ETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNL 748
Query: 769 -PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSV 827
P L ++ PF K+CG D +C DL + + +V + +V
Sbjct: 749 RPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF----SFMSLDCLVVGGPREFNVTV 804
Query: 828 TLKNKRESAYNTGIVVDFSENLFFA------------SFSLPVDGTEVTCQVAASQKSVA 875
T++N E +Y T + F +L + S+ L + T +V+ + KS +
Sbjct: 805 TVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASST-EVSGALKSTS 863
Query: 876 CDVGYPALKREQQVTFTINFDFNLQ-NLQNQASLSFQALSESQEENKADNLVNLKIPLLY 934
C + +P +VTF I FD + + +L N+ L SE+ L++P+ Y
Sbjct: 864 CSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKY 923
Query: 935 DAEI----HLTRSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVT-TGSVPVSM-AT 988
+ H + +NF + V + ++G + SL ++ VPV + T
Sbjct: 924 AVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQR---SLPISLVFLVPVRLNQT 980
Query: 989 VIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKEL 1048
VI PQ T +N +C+ + S F +E R +
Sbjct: 981 VIWDRPQVTFSENL-------------SSTCHTK------ERLPSHSDFLAE-LRKAPVV 1020
Query: 1049 NCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIY 1108
NC A C + C + ++ E+ + + + ++ + + + AEI +
Sbjct: 1021 NCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFT 1080
Query: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV--IIGSIIAGILLLLALVAILWKLGFFKRKYEKM 1166
++ + E EVP + I+GS + G+LLL + A L+KLGFFKR+Y+ M
Sbjct: 1081 LLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1140
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 371 bits (952), Expect = e-102
Identities = 347/1220 (28%), Positives = 543/1220 (44%), Gaps = 140/1220 (11%)
Query: 5 RTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLL 64
RT AA LLL AL+ L +N+ E F S+ FG +V Q+ N +W++
Sbjct: 3 RTRAA---LLLFTALATS-----LGFNLDTEELTAFRVDSAG-FGDSVVQYAN---SWVV 50
Query: 65 VGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMG 124
VG+P N+ G +Y+C ST CE + LQ V NMSLGL L
Sbjct: 51 VGAPQKITAANQTGGLYQC--GYSTGACEPIGLQ-------VPPEAVNMSLGLSLASTTS 101
Query: 125 TGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSLI-DVVVVCDESN 183
L CGP +CG Y TG+C + P QL+ + Q CP D+V + D S
Sbjct: 102 PSQLLACGPTVHHECGRNMYLTGLCFLLGPT-QLTQRLPVSRQECPRQEQDIVFLIDGSG 160
Query: 184 SIYP--WDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQ 241
SI + + NF+ + TQ L+Q++N + F ++ + +
Sbjct: 161 SISSRNFATMMNFVRAVISQFQ--RPSTQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLAS 218
Query: 242 TSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSM-LKAVIDQCN 300
Q G T T AIQ + A+ G RR A K+++V+TDG+ S+ K VI +
Sbjct: 219 VHQLQG-FTYTATAIQNVVHRLFHASYGARRDAAKILIVITDGKKEGDSLDYKDVIPMAD 277
Query: 301 HDNILRFGIAV-LGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGE 359
I+R+ I V L + NRN+ KE+ IAS P++ + F V D AL + L E
Sbjct: 278 AAGIIRYAIGVGLAFQNRNSW------KELNDIASKPSQEHIFKVEDFDALKDIQNQLKE 331
Query: 360 QIFSIEGT-VQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLI 418
+IF+IEGT +F++EM+Q GFSA ++ +L GAVG+F WSG G +
Sbjct: 332 KIFAIEGTETTSSSSFELEMAQEGFSAVFTPDGPVL--GAVGSFTWSG--------GAFL 381
Query: 419 FPKQ---AFDQILQDR--NHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSVNEN 473
+P F + Q+ SYLGYS V GAPR +TG+ V+++ +
Sbjct: 382 YPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQSLVLGAPRYQHTGKAVIFT-QVS 440
Query: 474 GNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIK 533
+ G QIGSYFG+ LCSVDVD D TD++L+GAP Y + G+V + +
Sbjct: 441 RQWRMKAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQTR--GGQVSVCPLP 498
Query: 534 EGILGQ--HQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNG 591
G L G +G RFG+A+ L D+N D DV++G+P E +N GAVY+++G
Sbjct: 499 RGWRRWWCDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHG 558
Query: 592 HQG-TIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQ 650
G +I +SQ+I GS S LQYFG++L G DL D + D+++GA GQV+ L ++
Sbjct: 559 VLGPSISPSHSQRIAGSQ--LSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQVLLLRTR 616
Query: 651 SIADVAIEASFTPEKI---------TLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNIT 701
+ V + F P +I +V++ + +C R + ++T
Sbjct: 617 PVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSSVT 676
Query: 702 LDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVNSLDLRVDI 760
LD R++ R F+E R L + V+ C + + D V + LR++
Sbjct: 677 LDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHCENFNLLLPSCVEDSVTPITLRLNF 736
Query: 761 SLENP------GTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPF 814
+L P L A ++ S+PF K+CG D +C +L + P +
Sbjct: 737 TLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISF-SFPGLKS--- 792
Query: 815 IVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTE--------VTCQ 866
++ N L V + N E +Y T I L S+ +G + +TC
Sbjct: 793 LLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGL---SYRYVAEGQKQGQLRSLHLTCD 849
Query: 867 VA--ASQK--SVACDVGYPALKREQQVTFTINFDFNLQN-LQNQASLSFQALSESQEENK 921
A SQ S +C + + + Q+TF FD + + L ++ L+ SE+
Sbjct: 850 SAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRT 909
Query: 922 ADNLVNLKIPLLYD----AEIHLTRSTNINFYEISSDGNVPSIVHSFE-------DVGPK 970
+ L++P+ Y H + +NF E S + +H ++ D+
Sbjct: 910 SKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSE-SEEKESHVAMHRYQVNNLGQRDLPVS 968
Query: 971 FIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQ-TDKAGDISCNADINPLKIG 1029
F + V V M + H PQ NP + + + A D + NP+
Sbjct: 969 INFWVPVELNQEAVWMDVEVSH-PQ-----NPSLRCSSEKIAPPASDFLAHIQKNPV--- 1019
Query: 1030 QTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTF 1089
L+C A C C + ++ E + + G
Sbjct: 1020 ------------------LDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 1061
Query: 1090 QTVQLTAAAEINTYNPEIYVI---EDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLL 1146
+ V + + AEI T++ +Y ++ + + K PT +I+GS I G+LLL
Sbjct: 1062 KKVSVVSVAEI-TFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLL 1120
Query: 1147 LALVAILWKLGFFKRKYEKM 1166
+ A+L+K+GFFKR+Y++M
Sbjct: 1121 ALITAVLYKVGFFKRQYKEM 1140
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 340 bits (872), Expect = 5e-93
Identities = 321/1214 (26%), Positives = 537/1214 (44%), Gaps = 134/1214 (11%)
Query: 13 LLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGF 72
LL VLA G +N+ + E IF + FG +V QF G+ L+VG+P
Sbjct: 8 LLSVLASYHG-------FNLDVEEPTIFQEDAGG-FGQSVVQF---GGSRLVVGAPLEVV 56
Query: 73 PENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCG 132
N+ G +Y C +T C+ + L ++ NMSLGL L + L CG
Sbjct: 57 AANQTGRLYDCAA--ATGMCQPIPL-------HIRPEAVNMSLGLTLAASTNGSRLLACG 107
Query: 133 PLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSL-IDVVVVCDESNSIYPWDAV 191
P + CG Y+ G C + +++ + AT CP +D+V + D S SI D
Sbjct: 108 PTLHRVCGENSYSKGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDF- 166
Query: 192 KNFLEKFVQGL--DIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDL 249
N ++ FVQ + T T L+QY+N ++ F ++T Q G L
Sbjct: 167 -NQMKGFVQAVMGQFEGTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKG-L 224
Query: 250 TNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESH-DGSMLKAVIDQCNHDNILRFG 308
T T I + +G R+SA K+++V+TDG+ + D VI Q I+R+
Sbjct: 225 TFTATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYA 284
Query: 309 IAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV 368
I V +A +E+ I+S P + + F V + AAL L E+I+++EGT
Sbjct: 285 IGV-----GHAFQGPTARQELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQ 339
Query: 369 -QGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQ---AF 424
+ +FQ EMSQ GFS + D L LGAVG+F WSG G ++P F
Sbjct: 340 SRASSSFQHEMSQEGFSTALTM--DGLFLGAVGSFSWSG--------GAFLYPPNMSPTF 389
Query: 425 DQILQDR--NHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSV-----NENGNIT 477
+ Q+ SYLGYS + V GAPR +TG+ V+++ + +T
Sbjct: 390 INMSQENVDMRDSYLGYSTELALWKGVQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVT 449
Query: 478 VIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGIL 537
G QIGSYFG+ LCSVDVD D TD++L+GAP Y + G+V + + G +
Sbjct: 450 ------GTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRGRV 501
Query: 538 GQH--QFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNG-HQG 594
L G +G RFG+A+ L D+N D DV +G+P E +N GAVY+++G +
Sbjct: 502 QWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASES 561
Query: 595 TIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIAD 654
I +SQ+I S LQYFG++L G DL D + D+++GA GQV+ L S +
Sbjct: 562 GISPSHSQRIASSQ--LSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSLPVLK 619
Query: 655 VAIEASFTPEKI-------------TLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNIT 701
V + F+P ++ L +A + L + S+ + Q ++ +++
Sbjct: 620 VGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSS--LDQLGDIQSSVRFDLA 677
Query: 702 LDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVNSLDLRVDI 760
LD R+TSR +F E L + + C + + + DVV+ + L ++
Sbjct: 678 LD----PGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNF 733
Query: 761 SL------ENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPF 814
SL P L S+ S+PF K+CG+DGLC DL + + +
Sbjct: 734 SLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTL----SFSGLQT 789
Query: 815 IVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFF-----ASFSLPVDGTEVTCQVAA 869
+ + L VT+ N E +Y T + + + L A + C+
Sbjct: 790 LTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVP 849
Query: 870 SQ----KSVACDVGYPALKREQQVTFTINFDFNLQ-NLQNQASLSFQALSESQEENKADN 924
++ +S C V +P TF + FD + + L ++ + A SE+ + + +
Sbjct: 850 TEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSKA 909
Query: 925 LVNLKIPLLYDAEIHLTR---STNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVTTGS 981
L++P+ Y ++R ST + S + + H + + +L +
Sbjct: 910 TFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYR------VNNLSQRDLA 963
Query: 982 VPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSEN 1041
+ ++ ++ N + V + + C ++ P + + +S
Sbjct: 964 ISINFWVPVL--------LNGVAVWDVVMEAPSQSLPCVSERKPPQHSDFLTQIS----- 1010
Query: 1042 FRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEIN 1101
+ L+C A C C + ++ E + + G + + V + + AEI
Sbjct: 1011 --RSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEI- 1067
Query: 1102 TYNPEIYVI---EDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGF 1158
T++ +Y ++ + + ++ +++ +I+GS + +LLL + A L+KLGF
Sbjct: 1068 TFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGF 1127
Query: 1159 FKRKYEKMTKNPDE 1172
FKR Y++M ++ E
Sbjct: 1128 FKRHYKEMLEDKPE 1141
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 333 bits (853), Expect = 8e-91
Identities = 327/1193 (27%), Positives = 543/1193 (45%), Gaps = 147/1193 (12%)
Query: 29 AYNVGLPEAKIFSGP-SSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDL 87
+YN+ + A+ FS P + FGY V Q GN ++VG+P G N G +Y+C
Sbjct: 25 SYNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQC--QS 75
Query: 88 STATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTG 147
T C + L+ S T+ LG+ L + G L C P ++ C Y +G
Sbjct: 76 GTGHCLPVTLRGSNY--------TSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSG 127
Query: 148 VCSDISPDFQ-LSASFSPATQPC-PSLIDVVVVCDESNSIYP--WDAVKNFLEKFVQGLD 203
+C + Q P Q C +D+V + D S S+ P + + +F++ ++ L
Sbjct: 128 LCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLS 187
Query: 204 IGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYA 263
T Q +Q++ + + F+ + Y +++ ++ LTNTFGAI Y
Sbjct: 188 --NTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHV-KHMLLLTNTFGAINYVATEV 244
Query: 264 YSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTK 323
+ G R ATKV++++TDGE+ D + A D I+R+ I + + TK
Sbjct: 245 FREELGARPDATKVLIIITDGEATDSGNIDAAKD------IIRYIIGIGKHFQ-----TK 293
Query: 324 NLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV-QGGDNFQMEMSQVG 382
+ + AS P + + L + L ++I+ IEGT Q +F ME+S G
Sbjct: 294 ESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSG 353
Query: 383 FSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAF--DQILQDRNHSSYLGYS 440
SAD S + ++ GAVGA W+G + + F ++ L + YLGY+
Sbjct: 354 ISADLSRGHAVV--GAVGAKDWAGGFLDLKAD----LQDDTFIGNEPLTPEVRAGYLGYT 407
Query: 441 VAAISTGESTHFVA-GAPRANYTGQIVLYSVNENG-NITVIQAHRGDQIGSYFGSVLCSV 498
V + + + T +A GAPR + G+++L+ + G + + +Q G QIGSYFG LC V
Sbjct: 408 VTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGV 467
Query: 499 DVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFLEGPEGIENTRFGSAI 558
DVD+D T++LL+GAP++ + + GRV+++ ++ + L+G G RFG AI
Sbjct: 468 DVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAI 525
Query: 559 AALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYF 618
AL+DIN DG DV VG+PLE Q GAVYI+NG G + + SQ+I G+ S +Q+F
Sbjct: 526 TALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQ--VLSGIQWF 581
Query: 619 GRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPEKI---------TLV 669
GRS+ G DL GD + DV++GA Q++ L S+ + D+ SF+P +I +
Sbjct: 582 GRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTS 641
Query: 670 NKNAQ-IILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKN 728
NK + + + +CF K + ++ TL DG +R RGLF L++N
Sbjct: 642 NKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTR--RRGLFPGGRHE-LRRN 698
Query: 729 MVVNQAQSCPEHIIYIQE-PSDVVNSLDLRVDISL-ENPGTS----------PALEAYSE 776
+ V + SC + + D+++ +++ ++ SL E GT P + S
Sbjct: 699 IAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSL 758
Query: 777 TAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESA 836
++ + IPF K+CGED C ++ L V PA + + + L+ ++L N E A
Sbjct: 759 HSETWEIPFEKNCGEDKKCEAN--LRVSFSPARSRALRLTAFAS--LSVELSLSNLEEDA 814
Query: 837 YNTGIVVDFSENLFFASF-------SLPVDGTEVTCQVAASQKSVACDVGYPALKREQQV 889
Y + + F L F +PV E+ + ++++C+V P K V
Sbjct: 815 YWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSV 874
Query: 890 TFTINFDFNLQNLQNQASLSFQALSESQEENK---ADNLVNLKIPLLYDAEIHLTRSTNI 946
+ F+ L N S+ A E+ DN IP+LY I
Sbjct: 875 ALQMMFN-TLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINI-------- 925
Query: 947 NFYEISSDGNVPSIVHSFEDVGPKF-----IFSLKVTTGSVPVSMATV--IIHIPQYTKE 999
+ D ++ SF GPK ++ +++ ++ T+ ++ +PQ E
Sbjct: 926 ----LIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSE 981
Query: 1000 KNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVT 1059
P+ + VQ + + C ++ + L C
Sbjct: 982 -GPITHQWSVQMEP--PVPC---------------------HYEDLERLPDAAEPCLPGA 1017
Query: 1060 CWLKDVHMKGEYFVNV--TTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTVTI 1117
+ V + E V V T + ASS F L ++ I+ + + + + + ++
Sbjct: 1018 LFRCPVVFRQEILVQVIGTLELVGEIEASSMF---SLCSSLSISFNSSKHFHLYGSNASL 1074
Query: 1118 PLMIMKPD---EKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRKY-EKM 1166
++MK D EK + V+ G I G+LLLL + +L+K+GFFKR EKM
Sbjct: 1075 AQVVMKVDVVYEKQMLYLYVLSG--IGGLLLLLLIFIVLYKVGFFKRNLKEKM 1125
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 300 bits (767), Expect = 7e-81
Identities = 224/739 (30%), Positives = 352/739 (47%), Gaps = 51/739 (6%)
Query: 174 DVVVVCDESNSIYPWD--AVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKT 231
++ ++ D S SI P D K+F+ ++ + L+QY + F+L +
Sbjct: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
Query: 232 KEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSM 291
+ +Q G +T T A+Q+ ++++ G RR A+KVMVV+TDG + +
Sbjct: 262 VMASLARVQNITQVGS-VTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
Query: 292 -LKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAAL 350
L VI+ + RF I V + +E+ IAS P E + F V++ AL
Sbjct: 321 NLTTVINSPKMQGVERFAIGV-----GEEFKSARTARELNLIASDPDETHAFKVTNYMAL 375
Query: 351 LEKAGTLGEQIFSIEGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIV- 409
L I S+EGTV GD +++Q+GFSA + +L LGAVGAF WSG +
Sbjct: 376 DGLLSKLRYNIISMEGTV--GDALHYQLAQIGFSAQILDERQVL-LGAVGAFDWSGGALL 432
Query: 410 --QKTSHGHLIFPKQAFDQILQDRNHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVL 467
++ G + A + +S YLGY+VA + S ++AGAPR + G +
Sbjct: 433 YDTRSRRGRFLNQTAAAAADAEAAQYS-YLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFE 491
Query: 468 YSVNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRV 527
E + + G+Q+GSYFGS LC VD+D D TD LLV AP Y + EEGRV
Sbjct: 492 LQ-KEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEEGRV 548
Query: 528 YLFTIKE--GILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLE------ 579
Y++ + E G + L G G N RFG A+AA+ D++ D DV +G+PLE
Sbjct: 549 YVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADD 608
Query: 580 NQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIG 639
+ G+VYIYNGH + SQ+I S A LQYFG S+ G D++GD + D+++G
Sbjct: 609 GASFGSVYIYNGHWDGLSASPSQRIRASTVA--PGLQYFGMSMAGGFDISGDGLADITVG 666
Query: 640 AFGQVVQLWSQSIADVAIEASFTPEKITLVNKNAQIILKLCFSAKFRPTKQNNQV-AIVY 698
GQ V S+ + + + +FTP + + N + ++LCF T + + +
Sbjct: 667 TLGQAVVFRSRPVVRLKVSMAFTPSALP-IGFNGVVNVRLCFEISSVTTASESGLREALL 725
Query: 699 NITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE----PSDVVNSL 754
N TLD D R + + CL++ + +Q C + ++ E D ++
Sbjct: 726 NFTLDVDVGKQRRRLQCSDVRSCLGCLRE--WSSGSQLCEDLLLMPTEGELCEEDCFSNA 783
Query: 755 DLRVDISLENP-----GTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAA 809
++V L+ P P L+ Y+E +F +P+ K C C+++L Q+
Sbjct: 784 SVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAEL-----QLATT 838
Query: 810 QEQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTC---Q 866
Q +V K LT ++ L N E +Y T + +++ NL P + C Q
Sbjct: 839 VSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKP-PSPNIQCDDPQ 897
Query: 867 VAASQKSVACDVGYPALKR 885
AS + C +G+P LKR
Sbjct: 898 PVASVLIMNCRIGHPVLKR 916
Score = 43.5 bits (101), Expect = 0.001
Identities = 21/68 (30%), Positives = 43/68 (63%), Gaps = 5/68 (7%)
Query: 1102 TYNPEIYV---IEDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGF 1158
++N +Y E++ I ++ +K ++ +P +II + G+L+L+ ++ IL+K GF
Sbjct: 1094 SFNKSLYEGLNAENHRTKITVVFLKDEKYHSLP--IIIKGSVGGLLVLIVILVILFKCGF 1151
Query: 1159 FKRKYEKM 1166
FKRKY+++
Sbjct: 1152 FKRKYQQL 1159
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 288 bits (736), Expect = 3e-77
Identities = 273/967 (28%), Positives = 446/967 (46%), Gaps = 121/967 (12%)
Query: 249 LTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFG 308
LTNTFGAI Y + G R ATKV++++TDGE+ D + A D I+R+
Sbjct: 147 LTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKD------IIRYI 200
Query: 309 IAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV 368
I + + TK + + AS P + + L + L ++I+ IEGT
Sbjct: 201 IGIGKHFQ-----TKESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTS 255
Query: 369 -QGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAF--D 425
Q +F ME+S G SAD S + ++ GAVGA W+G + + F +
Sbjct: 256 KQDLTSFNMELSSSGISADLSRGHAVV--GAVGAKDWAGGFLDLKAD----LQDDTFIGN 309
Query: 426 QILQDRNHSSYLGYSVAAISTGESTHFVA-GAPRANYTGQIVLYSVNENG-NITVIQAHR 483
+ L + YLGY+V + + + T +A GAPR + G+++L+ + G + + +Q
Sbjct: 310 EPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIH 369
Query: 484 GDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFL 543
G QIGSYFG LC VDVD+D T++LL+GAP++ + + GRV+++ ++ + L
Sbjct: 370 GTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGE--QRGGRVFIYQRRQLGFEEVSEL 427
Query: 544 EGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQK 603
+G G RFG AI AL+DIN DG DV VG+PLE Q GAVYI+NG G + + SQ+
Sbjct: 428 QGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQR 485
Query: 604 ILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTP 663
I G+ S +Q+FGRS+ G DL GD + DV++GA Q++ L S+ + D+ SF+P
Sbjct: 486 IEGTQ--VLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSP 543
Query: 664 EKI---------TLVNKNAQ-IILKLCFSAKFRPTKQNNQVAIVYNITLDADGFSSRVTS 713
+I + NK + + + +CF K + ++ TL DG +R
Sbjct: 544 AEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTR--R 601
Query: 714 RGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVNSLDLRVDISL-ENPGTS--- 768
RGLF L++N+ V + SC + + D+++ +++ ++ SL E GT
Sbjct: 602 RGLFPGGRHE-LRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQ 660
Query: 769 ------PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKR 822
P + S ++ + IPF K+CGED C ++ L V PA + + +
Sbjct: 661 RAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEAN--LRVSFSPARSRALRLTAFAS-- 716
Query: 823 LTFSVTLKNKRESAYNTGIVVDFSENLFFASF-------SLPVDGTEVTCQVAASQKSVA 875
L+ ++L N E AY + + F L F +PV E+ + ++++
Sbjct: 717 LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALS 776
Query: 876 CDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENK---ADNLVNLKIPL 932
C+V P K V + F+ L N S+ A E+ DN IP+
Sbjct: 777 CNVSSPIFKAGHSVALQMMFN-TLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPI 835
Query: 933 LYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGPKF-----IFSLKVTTGSVPVSMA 987
LY I + D ++ SF GPK ++ +++ ++
Sbjct: 836 LYPINI------------LIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIP 883
Query: 988 TV--IIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHT 1045
T+ ++ +PQ E P+ + VQ + + C ++
Sbjct: 884 TLEAVVGVPQPPSE-GPITHQWSVQMEP--PVPC---------------------HYEDL 919
Query: 1046 KELNCRTASCSNVTCWLKDVHMKGEYFVNV--TTRIWNGTFASSTFQTVQLTAAAEINTY 1103
+ L C + V + E V V T + ASS F L ++ I+
Sbjct: 920 ERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIEASSMF---SLCSSLSISFN 976
Query: 1104 NPEIYVIEDNTVTIPLMIMKPD---EKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFK 1160
+ + + + + ++ ++MK D EK + V+ G I G+LLLL + +L+K+GFFK
Sbjct: 977 SSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSG--IGGLLLLLLIFIVLYKVGFFK 1034
Query: 1161 RKY-EKM 1166
R EKM
Sbjct: 1035 RNLKEKM 1041
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 223 bits (569), Expect = 6e-58
Identities = 235/886 (26%), Positives = 378/886 (42%), Gaps = 149/886 (16%)
Query: 380 QVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQD--------- 430
Q GFS D+ D L++G G+F W G ++ T+ I +F IL+
Sbjct: 201 QAGFSLDFYKNGD-LIVGGPGSFYWQGQVI--TASVADIIANYSFKDILRKLAGEKQTEV 257
Query: 431 ---RNHSSYLGYSVAAIS-TGESTH-FVAGAPRANYTGQIVLYSVNENGNITVIQAHRGD 485
SYLGYSVAA TG+S VAG PR V S+ + ++T IQ G+
Sbjct: 258 APASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYV--SIINSTDMTFIQNFTGE 315
Query: 486 QIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMS----DLKKEEGRVYLFTIKEGILGQH- 540
Q+ SYFG + DV+ D + DVL VGAP++M +E G++YL+ +L +
Sbjct: 316 QMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDP 374
Query: 541 QFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNS-GAVYIYNGHQGTIRTK 599
Q L G E RFGSA+A L D+N DG+ND+ +G P ++ G V IYNG++ + TK
Sbjct: 375 QILTGTETFG--RFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTK 432
Query: 600 YSQKILGSDGAFRSHL--QYFGRSLDGYGDLNGDSITDVSIGAF--GQVVQLWSQSIADV 655
SQ + G + SH FG +L G D++ + D+ +GAF G+V ++ + V
Sbjct: 433 PSQVL---QGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTV 489
Query: 656 AIEASFTPEKITLVNKNAQI----ILKLCFSAKFRPTKQNNQVA--IVYNITLDADGFSS 709
+ P I L NK Q+ CFS + + +A IV + D
Sbjct: 490 DAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQ 549
Query: 710 R-VTSRGLFKENNERCLQKNMVVNQAQS--CPEHIIYIQEPS---DVVNSLDLRVDISL- 762
+ R LF +N++ +V+ + +S C + I+Y+++ + D ++ +++ ++ SL
Sbjct: 550 KGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLD 609
Query: 763 -----ENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVS 817
E P L Y E DCGED LC+ DL L R + I+
Sbjct: 610 ESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSAR----PDKHQVIIG 665
Query: 818 NQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDG-TEVTCQVAASQ--KSV 874
++N L + +N+ E AY + V E + G ++C+ + V
Sbjct: 666 DEN-HLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMV 724
Query: 875 ACDVGYP-------------ALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENK 921
CD+G P A+ R ++ +INFD +++ S ++N
Sbjct: 725 VCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRS--------------SNKDNP 770
Query: 922 ADNLVNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSIV------------HSFEDVGP 969
N V+L+I + A++ EI + P IV H E+VGP
Sbjct: 771 DSNFVSLQINITAVAQV-----------EIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGP 819
Query: 970 --KFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISC--NADINP 1025
+ I+ L G +S + + P ++ L+Y+ +QT G + C N +INP
Sbjct: 820 LVEHIYELH-NIGPSTISDTILEVGWP-FSARDEFLLYIFHIQT--LGPLQCQPNPNINP 875
Query: 1026 LKIGQTSS-------SVSFKSENFRH-----------------TKELNCRTASCSNVTCW 1061
I +S S ++ H K LNC C ++C
Sbjct: 876 QDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCA 935
Query: 1062 LKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINT----YNPEIYVIEDNTVTI 1117
+ + + V +R+W TF L + Y + + + ++ I
Sbjct: 936 VGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAI 995
Query: 1118 PLMIM--KPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKR 1161
++ P+ +P VII +I+ G+L+L L LWK GFF R
Sbjct: 996 KTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDR 1041
Score = 45.4 bits (106), Expect = 3e-04
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 20/181 (11%)
Query: 2 GPERTGAAPLPLLLVLALSQGIL---NCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFI-N 57
GP + A + L A + G+L C A+N+ + + ++SGP FGYAV I +
Sbjct: 8 GPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67
Query: 58 PKGNWLLVGSPWSGFPENRM---GDVYKCPVDL-STATCEKLNLQTSTS-------IPNV 106
+ +LVG+P + + + G VY CP +A C ++ T+ +
Sbjct: 68 ARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEP 127
Query: 107 TEMKTNMSLGLILTRNMGTGGFLTCGPLW---AQQCGNQYYTTGVCSDISPDFQLSASFS 163
E K+N G + + G + C PL+ + + G C +F A FS
Sbjct: 128 IEFKSNQWFGATVKAHKGK--VVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFS 185
Query: 164 P 164
P
Sbjct: 186 P 186
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 216 bits (549), Expect = 1e-55
Identities = 210/838 (25%), Positives = 406/838 (48%), Gaps = 91/838 (10%)
Query: 392 DILMLGAVGAFGWSGTI--VQKTSHGHLIFPKQAFDQILQDRNHSSYLGYSVAA--ISTG 447
+++++GA G+F W+GTI + T + +L + D+++ +R ++ YLGY+V A S
Sbjct: 205 ELVVMGAPGSFYWAGTIKVLNLTDNTYL----KLNDEVIMNRRYT-YLGYAVTAGHFSHP 259
Query: 448 ESTHFVAGAPRANYTGQIVLYSVNE-NGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTIT 506
+ V GAP+ G++ ++ + +G + I G ++GSYFGS LC+VD++ D ++
Sbjct: 260 STIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLS 319
Query: 507 DVLLVGAPMYMSDLKKEEGRVYLFTIK-EGILGQHQFLEGPEGIENTRFGSAIAALSDIN 565
D LLVGAPM+ S+++ +EG+V ++ + G L + L G +G N FG +IA+L D++
Sbjct: 320 D-LLVGAPMF-SEIR-DEGQVTVYINRGNGALEEQLALTG-DGAYNAHFGESIASLDDLD 375
Query: 566 MDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGY 625
DGF DV +G+P E+ +GAVYIY+G G I +YS K+ G L+ FG+S+ G
Sbjct: 376 NDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQ--KINPVLRMFGQSISGG 433
Query: 626 GDLNGDSITDVSIGAF--GQVVQLWSQSIADVAIEASFTPEKITLVNKNAQ--------I 675
D++G+ DV++GAF VV L ++ + V + + F P I + +
Sbjct: 434 IDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDV-SIFLPGSINITAPQCHDGQQPVNCL 492
Query: 676 ILKLCFS--AKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQ 733
+ CFS K P + ++ ++ G RV L E + +K +
Sbjct: 493 NVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYF-VLLGETMGQVTEKLQLTYM 551
Query: 734 AQSCPEHIIYI-QEPSDVVNSLDLRVDISL----------ENPGTSPAL--EAYSETAKV 780
++C ++ ++ + DV++ + SL E P +P L + + A+
Sbjct: 552 EETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQK 611
Query: 781 FSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQP--FIVSNQNKRLTFSVTLKNKRESAYN 838
F ++C + C +DL L + + ++ ++ ++ K ++ ++++ N + AY+
Sbjct: 612 NQTVFERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYD 670
Query: 839 TGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTINFDFN 898
+ + S LFF + + ++C++ S + C VG+P ++ + + F++ FD +
Sbjct: 671 ANVSFNVSRELFFINM-WQKEEMGISCELLESD-FLKCSVGFPFMRSKSKYEFSVIFDTS 728
Query: 899 LQNLQNQASLSFQALSES----QEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSD 954
+ + + LSF ++S + E+ DN + L +PL+++ + +T + +
Sbjct: 729 HLSGEEEV-LSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGES 787
Query: 955 GNVPSIVHSFEDVGPKF---IFSLKV-TTGSVPVSMATVIIHIPQYTKEKNPLMYLTG-- 1008
+ + + +D+ F +L+V TG + ++V I P M+
Sbjct: 788 VDAANFI-QLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEM 846
Query: 1009 VQTDKAGDISCNADINPLKIGQTSSSV-----SFKSENFRHTKE-----LNCRTASCSNV 1058
V + G+ S + P I Q ++ +F +++ R + ++C TA C N
Sbjct: 847 VVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHC-NF 905
Query: 1059 TCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIE-----DN 1113
+ K+ + ++ + T I + +Q + A++ +P + V+E
Sbjct: 906 SALAKEESRTIDIYMLLNTEI----LKKDSSSVIQFMSRAKVKV-DPALRVVEIAHGNPE 960
Query: 1114 TVTIPLMIMKPDEKAEVPTGVIIGSIIA-----GILLLLALVAILWKLGFFKRKYEKM 1166
VT+ + E P G ++G IIA GIL+ L L +LWK+GFF+R+Y+++
Sbjct: 961 EVTVVFEALHNLE----PRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEI 1014
Score = 39.3 bits (90), Expect = 0.022
Identities = 41/149 (27%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 7 GAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVG 66
GA L LL+ + GI AYN+ F GP+ FGYAV + + W+LVG
Sbjct: 9 GAGRLRALLLALVVAGIP--AGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVG 66
Query: 67 SPWSGFPEN----RMGDVYKCPVDLS-TATCEKLNL-----QTSTSIPNVTEMKTNMSLG 116
+P + + G V+KC V + C +L++ + ++ E + + +G
Sbjct: 67 APKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMG 126
Query: 117 LILTRN-MGTGGFLTCGPLWAQQCGNQYY 144
+ L R G L C W N YY
Sbjct: 127 VSLARQPKADGRVLACAHRWK----NIYY 151
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 204 bits (519), Expect = 4e-52
Identities = 218/905 (24%), Positives = 393/905 (43%), Gaps = 144/905 (15%)
Query: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAF 424
+G ++G + F Q G +A ++ ++ GA G + W G IV+ + F F
Sbjct: 176 DGRLRGHEKFGS--CQQGVAATFTKDFHYIVFGAPGTYNWKG-IVRVEQKNNTFFDMNIF 232
Query: 425 -------------DQILQDRNHSSYLGYSVAA----ISTGESTHFVAGAPRANYTGQIVL 467
D+ L +SYLG+S+ + +S E T FV+GAPRAN++G +VL
Sbjct: 233 EDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVL 291
Query: 468 YSVN-ENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGR 526
+ ++ ++ G+ + S FG + VD++KD D++ +GAP Y + G
Sbjct: 292 LKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGA 350
Query: 527 VYLFTIKEGILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAV 586
VY++ ++G + + G +++ FG A+ + DIN DG+ D+ VG+P ++ G V
Sbjct: 351 VYVYMNQQGRWNNVKPIR-LNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDL--GKV 407
Query: 587 YIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQ 646
+IY+G I TK +Q + G YFG S+ G DL+ +S DV++G+ V
Sbjct: 408 FIYHGSANGINTKPTQVLKGIS-------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVT 460
Query: 647 LW-SQSIADVAIEASFTPEKITLVNKNAQ-------IILKLCFSAKFRPTKQNNQVAIVY 698
++ S+ + ++ + TP +I L K A + +K CF P N ++IV
Sbjct: 461 IFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVG 520
Query: 699 NITLDADGFSSRVTSRGLFKENNE--RCLQKNMVVNQAQS-CPEHIIYIQEP-SDVVNSL 754
+ + + S ++SR F+ + Q+ + Q Q C E +++Q+ D + +
Sbjct: 521 TLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPI 580
Query: 755 DLRVDISLENPGTSPALEAYSETAKVFS----------IPFHKD-CGEDGLCISDLVLDV 803
+ + ++ P + + + E + + + F K+ CG+D +C S+L L+
Sbjct: 581 PITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEY 640
Query: 804 R------------QIPAAQEQPFIVSNQNKRLTFSVTLKNKR----------ESAYNTGI 841
+ +P + P +V K + +T+ N + A+ +
Sbjct: 641 KFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKL 700
Query: 842 VVDFSENLFFASFS--LPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTF-----TIN 894
+ F + L ++++ +++C + C++G P KR VTF T
Sbjct: 701 IATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNP-FKRNSNVTFYLVLSTTE 759
Query: 895 FDFNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSD 954
F+ +L L + S ++N A K+ + E+ L+ S ++
Sbjct: 760 VTFDTPDLDINLKLE----TTSNQDNLAPITAKAKVVI----ELLLSVSGVAKPSQVYFG 811
Query: 955 GNV--PSIVHSFEDVGPKFIFSLKVTTGSVPVS---MATVIIHIPQYTKEKNPLMYLTGV 1009
G V + S ++VG + +V P++ AT+ I P+ L+YL V
Sbjct: 812 GTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKV 871
Query: 1010 QTDKAGDISCNA--DINPLKIGQTSSSVS--------------FKSENFRHTKELNCRT- 1052
++ ++C +IN L + ++ +S F R + LNC
Sbjct: 872 ESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVN 931
Query: 1053 ASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQT----------VQLTAAAEINT 1102
+C N+ C L+ + K + +R+WN TF + + +TAAAE N
Sbjct: 932 VNCVNIRCPLRGLDSKASLILR--SRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAE-NI 988
Query: 1103 YNPE------IYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKL 1156
P + V TV + + VP +I+ +I+AGIL+L LV ILWK
Sbjct: 989 RLPNAGTQVRVTVFPSKTVA---------QYSGVPWWIILVAILAGILMLALLVFILWKC 1039
Query: 1157 GFFKR 1161
GFFKR
Sbjct: 1040 GFFKR 1044
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 204 bits (519), Expect = 4e-52
Identities = 218/905 (24%), Positives = 393/905 (43%), Gaps = 144/905 (15%)
Query: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAF 424
+G ++G + F Q G +A ++ ++ GA G + W G IV+ + F F
Sbjct: 176 DGRLRGHEKFGS--CQQGVAATFTKDFHYIVFGAPGTYNWKG-IVRVEQKNNTFFDMNIF 232
Query: 425 -------------DQILQDRNHSSYLGYSVAA----ISTGESTHFVAGAPRANYTGQIVL 467
D+ L +SYLG+S+ + +S E T FV+GAPRAN++G +VL
Sbjct: 233 EDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEIT-FVSGAPRANHSGAVVL 291
Query: 468 YSVN-ENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGR 526
+ ++ ++ G+ + S FG + VD++KD D++ +GAP Y + G
Sbjct: 292 LKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGA 350
Query: 527 VYLFTIKEGILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAV 586
VY++ ++G + + G +++ FG A+ + DIN DG+ D+ VG+P ++ G V
Sbjct: 351 VYVYMNQQGRWNNVKPIR-LNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDL--GKV 407
Query: 587 YIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQ 646
+IY+G I TK +Q + G YFG S+ G DL+ +S DV++G+ V
Sbjct: 408 FIYHGSANGINTKPTQVLKGIS-------PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVT 460
Query: 647 LW-SQSIADVAIEASFTPEKITLVNKNAQ-------IILKLCFSAKFRPTKQNNQVAIVY 698
++ S+ + ++ + TP +I L K A + +K CF P N ++IV
Sbjct: 461 IFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVG 520
Query: 699 NITLDADGFSSRVTSRGLFKENNE--RCLQKNMVVNQAQS-CPEHIIYIQEP-SDVVNSL 754
+ + + S ++SR F+ + Q+ + Q Q C E +++Q+ D + +
Sbjct: 521 TLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPI 580
Query: 755 DLRVDISLENPGTSPALEAYSETAKVFS----------IPFHKD-CGEDGLCISDLVLDV 803
+ + ++ P + + + E + + + F K+ CG+D +C S+L L+
Sbjct: 581 PITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEY 640
Query: 804 R------------QIPAAQEQPFIVSNQNKRLTFSVTLKNKR----------ESAYNTGI 841
+ +P + P +V K + +T+ N + A+ +
Sbjct: 641 KFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKL 700
Query: 842 VVDFSENLFFASFS--LPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTF-----TIN 894
+ F + L ++++ +++C + C++G P KR VTF T
Sbjct: 701 IATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNP-FKRNSNVTFYLVLSTTE 759
Query: 895 FDFNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSD 954
F+ +L L + S ++N A K+ + E+ L+ S ++
Sbjct: 760 VTFDTPDLDINLKLE----TTSNQDNLAPITAKAKVVI----ELLLSVSGVAKPSQVYFG 811
Query: 955 GNV--PSIVHSFEDVGPKFIFSLKVTTGSVPVS---MATVIIHIPQYTKEKNPLMYLTGV 1009
G V + S ++VG + +V P++ AT+ I P+ L+YL V
Sbjct: 812 GTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKV 871
Query: 1010 QTDKAGDISCNA--DINPLKIGQTSSSVS--------------FKSENFRHTKELNCRT- 1052
++ ++C +IN L + ++ +S F R + LNC
Sbjct: 872 ESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVN 931
Query: 1053 ASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQT----------VQLTAAAEINT 1102
+C N+ C L+ + K + +R+WN TF + + +TAAAE N
Sbjct: 932 VNCVNIRCPLRGLDSKASLILR--SRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAE-NI 988
Query: 1103 YNPE------IYVIEDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKL 1156
P + V TV + + VP +I+ +I+AGIL+L LV ILWK
Sbjct: 989 RLPNAGTQVRVTVFPSKTVA---------QYSGVPWWIILVAILAGILMLALLVFILWKC 1039
Query: 1157 GFFKR 1161
GFFKR
Sbjct: 1040 GFFKR 1044
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 203 bits (517), Expect = 7e-52
Identities = 225/858 (26%), Positives = 374/858 (43%), Gaps = 111/858 (12%)
Query: 380 QVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSH--GHLIFPKQAFDQI---LQDRNHS 434
Q GFSA+++ ++ LG G++ W G I+ T +P+ + + LQ R S
Sbjct: 206 QGGFSAEFTKTGRVV-LGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQAS 264
Query: 435 S-----YLGYSVAA--ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQI 487
S YLGYSVA S ++ FVAG P+ N T V ++ +I + G+Q+
Sbjct: 265 SIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYV--TILNGSDIRSLYNFSGEQM 322
Query: 488 GSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLK----KEEGRVYLFTIKEGILGQHQFL 543
SYFG + + DV+ D + D LLVGAP+ M +E GRVY++ L
Sbjct: 323 ASYFGYAVAATDVNGDGLDD-LLVGAPLLMDRTPDGRPQEVGRVYVY------------L 369
Query: 544 EGPEGIENT------------RFGSAIAALSDINMDGFNDVIVGSPLENQNS-GAVYIYN 590
+ P GIE T RFGS++ L D++ DG+NDV +G+P + G V+++
Sbjct: 370 QHPAGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFP 429
Query: 591 GHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG---QVVQ- 646
G G + +K SQ +L A +FG +L G DL+G+ D+ +G+FG VV
Sbjct: 430 GGPGGLGSKPSQ-VLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYR 488
Query: 647 ---LWSQSIADVAIEASFTPEKITLV---NKNAQIILKLCFSAKFRPTKQNNQVAIVYNI 700
+ S S + A F PE+ + N A I L C +A + + I + +
Sbjct: 489 GRPIVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADS----IGFTV 544
Query: 701 TLDADGFSSRV-TSRGLFKENNERCLQKNMVVNQA--QSCPEHIIYIQEPS---DVVNSL 754
L D + R LF + + L + +++ + C E IY++ S D ++ +
Sbjct: 545 ELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPI 604
Query: 755 DLRVDISLE------NPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPA 808
+ ++ SL+ + G PAL S++ DCGED +C+ DL L+V
Sbjct: 605 HIALNFSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEV----- 659
Query: 809 AQEQPFIVSNQNKRLTFSVTLKNKRES-AYNTGIVVDFSENLFFASFSL-PVDGTEVTCQ 866
EQ + L + +N E AY + V ++ P + + ++C
Sbjct: 660 FGEQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCD 719
Query: 867 VAASQKS--VACDVGYPALKREQQVTFTINFDF-NLQNLQNQASLSFQALSESQEENKAD 923
A +S + CD+G P +K + + F +L++ + FQ LS++ +++D
Sbjct: 720 YFAVNQSRLLVCDLGNP-MKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSD 778
Query: 924 NLVNLKIPLLYDAEIHLTRSTNINFYEIS-SDGNVPSIVHSFEDVGPKF--IFSLKVTTG 980
+V+ ++ + A++ L + SD + ED+GP ++ L + G
Sbjct: 779 -VVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYEL-INQG 836
Query: 981 SVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISC--NADINPLKIG--------- 1029
+S + + PQ E L+Y+T V ++C N INP +
Sbjct: 837 PSSISQGVLELSCPQ-ALEGQQLLYVTRVT-----GLNCTTNHPINPKGLELDPEGSLHH 890
Query: 1030 QTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTF 1089
Q +S + L C A C + C L +H + + + R+W TF
Sbjct: 891 QQKREAPSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREH 950
Query: 1090 QTVQLTAAAEINTYNPEIYVI------EDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGI 1143
Q L A ++ ++ V + K + VP +II +I+ G+
Sbjct: 951 QPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGL 1010
Query: 1144 LLLLALVAILWKLGFFKR 1161
LLL L+ IL+KLGFFKR
Sbjct: 1011 LLLGLLIYILYKLGFFKR 1028
Score = 33.1 bits (74), Expect = 1.6
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 10/106 (9%)
Query: 2 GPERTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINP--K 59
GP R LPLLL+L + +N+ + SGP FG++V +F P
Sbjct: 18 GPRRRPPL-LPLLLLLLPPPPRVG---GFNLDAEAPAVLSGPPGSFFGFSV-EFYRPGTD 72
Query: 60 GNWLLVGSPWSGFPENRM---GDVYKCPVDLSTATCEKLNLQTSTS 102
G +LVG+P + + + G VY CP S C + + S
Sbjct: 73 GVSVLVGAPKANTSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGS 118
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 201 bits (510), Expect = 4e-51
Identities = 213/870 (24%), Positives = 386/870 (44%), Gaps = 93/870 (10%)
Query: 371 GDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGT--IVQKTSHGHLIFPKQAFDQIL 428
G+NF Q G S+ Y+ D++++GA G+ W+G+ + T++ + +AF
Sbjct: 192 GENFAS--CQAGISSFYTK--DLIVMGAPGSSYWTGSLFVYNITTNKY-----KAFLDKQ 242
Query: 429 QDRNHSSYLGYSVAA--ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQ 486
SYLGYSV A + +T V GAP+ G+ ++S++E + ++ +G +
Sbjct: 243 NQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEK-ELNILHEMKGKK 301
Query: 487 IGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLF----------TIKEGI 536
+GSYFG+ +C+VD++ D +D LLVGAPM + +EEGRV+++ ++ +
Sbjct: 302 LGSYFGASVCAVDLNADGFSD-LLVGAPMQSTI--REEGRVFVYINSGSGAVMNAMETNL 358
Query: 537 LGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTI 596
+G ++ RFG +I L DI+ DGF DV +G+P E+ GA+YIYNG I
Sbjct: 359 VGSDKYA--------ARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGI 410
Query: 597 RTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVA 656
+ +SQ+I G L FG+S+ G D + + DV++GAF + ++ V
Sbjct: 411 SSTFSQRIEGLQ--ISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVI 468
Query: 657 IEASFT-PEKITLVN--------KNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDADGF 707
++AS + PE + + I L LCFS K + + + YN++LD +
Sbjct: 469 VDASLSHPESVNRTKFDCVENGWPSVCIDLTLCFSYKGKEVP--GYIVLFYNMSLDVNR- 525
Query: 708 SSRVTSRGLFKEN--NERCLQKNMVVNQAQSCPEHIIYI-QEPSDVVNSLDLRVDISL-- 762
+ R F N ++ V ++ +C H ++ ++ D++ + + L
Sbjct: 526 KAESPPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGP 585
Query: 763 ---------ENPGTSPALEAYSE-TAKVFSIPFHKDCGEDGLCISDLVLDVR--QIPAAQ 810
E P P L+ E +I F + C + C +DL + + + +
Sbjct: 586 HVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHE 644
Query: 811 EQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAAS 870
+ ++ K L +V+L N + AY T + V L+F L ++ ++ C+V +
Sbjct: 645 NKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKI-LELEEKQINCEVTDN 703
Query: 871 QKSVA--CDVGYPALKREQQVTFTINFDF-NLQNLQNQASLSFQALSESQEE--NKADNL 925
V C +GY + ++ + D +L + S++ A E++EE N +
Sbjct: 704 SGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSR 763
Query: 926 VNLKIPLLYDAEIHLTRSTN-INFYEISSDGNVPSIVHSFEDVGPKFIFSLKVTTGSVPV 984
V + IPL Y+ ++ + N +F S+D N P E + F + TG+
Sbjct: 764 VTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETC-MVEKMNLTFHV---INTGNSMA 819
Query: 985 SMATVIIHIP-QYTKEKNPLMYLTGVQTDKAGDIS-------CNADINPLKIGQTSSSVS 1036
+V I +P ++ + + L + VQT G+ C + + V
Sbjct: 820 PNVSVEIMVPNSFSPQTDKLFNILDVQT-TTGECHFENYQRVCALEQQKSAMQTLKGIVR 878
Query: 1037 FKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTR----IWNGTFASSTFQTV 1092
F S+ + C N C + E V++ I S+ +
Sbjct: 879 FLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEI 938
Query: 1093 QLTAAAEINTYNPEIYVIEDNTVTIPLMIMKPDEKAEVPTGVII-GSIIAGILLLLALVA 1151
+ T E N E+ ++N + L + T VII S++ G+++LL +
Sbjct: 939 RATGFPEPNPRVIELNK-DENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISY 997
Query: 1152 ILWKLGFFKRKYEKMTKNPDEIDETTELSS 1181
++WK GFFKR+Y+ + + + D + ++S
Sbjct: 998 VMWKAGFFKRQYKSILQEENRRDSWSYINS 1027
Score = 67.8 bits (164), Expect = 6e-11
Identities = 77/292 (26%), Positives = 111/292 (38%), Gaps = 54/292 (18%)
Query: 2 GPERTGAAP-LPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKG 60
GP R + LLL L + G YNV A ++ GP + FGY+V +
Sbjct: 10 GPRRAAVRETVMLLLCLGVPTG-----RPYNVDTESALLYQGPHNTLFGYSVVLHSHGAN 64
Query: 61 NWLLVGSPWSGFPEN----RMGDVYKCPVDLSTA-TCEKLNLQTSTSIP---NVTEMKTN 112
WLLVG+P + + N G +Y+C + + TCE+L L + P E + N
Sbjct: 65 RWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDN 124
Query: 113 MSLGLILTRNMG-TGGFLTCGPLWAQQCGNQYY-------TTGVCSDISPDFQLSASFSP 164
LG+ L+R G G +TCG W N +Y TG C + PD L S
Sbjct: 125 QWLGVTLSRQPGENGSIVTCGHRWK----NIFYIKNENKLPTGGCYGVPPD--LRTELSK 178
Query: 165 ATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQ---GLDIGPTKTQVGL----IQYA 217
PC D VK F E F G+ TK + + Y
Sbjct: 179 RIAPCYQ-----------------DYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYW 221
Query: 218 NNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASG 269
V+N+ T K K + ++G L + GA + ++ G
Sbjct: 222 TGSLFVYNITTNKYK--AFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGG 271
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 199 bits (507), Expect = 1e-50
Identities = 235/886 (26%), Positives = 386/886 (43%), Gaps = 121/886 (13%)
Query: 380 QVGFSADYSSQNDILMLGAVGAFGWSGTIVQKT----------SHGHLIFPKQAFDQILQ 429
Q GFS D++ + +L LG G+F W G ++ + + + Q + Q
Sbjct: 140 QGGFSIDFTKADRVL-LGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQ 198
Query: 430 DRNHSSYLGYSVAA--ISTGESTHFVAGAPRANYT-GQIVLYSVNENGNITVIQAHRGDQ 486
SYLGYSVA + FV+G PRA T G + +Y + N++ + G+Q
Sbjct: 199 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTGEQ 255
Query: 487 IGSYFGSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRVYLFTIKEGILGQHQF 542
+ +YFG + + D++ D DV +GAP++M SD K +E G+V + + Q
Sbjct: 256 MAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 314
Query: 543 LEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQN-SGAVYIYNGHQGTIRTKYS 601
L G E RFGSAIA L D++ DGFND+ + +P ++ G VYI+NG + S
Sbjct: 315 LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPS 372
Query: 602 QKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG--QVVQLWSQSIADVAIEA 659
Q IL A RS FG S+ G D++ + D+ +GAFG + + ++ + V
Sbjct: 373 Q-ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGL 431
Query: 660 SFTPEKITLVNKNAQI---ILKL-CFSAKF---------RPTKQNNQVAIVYNITLDADG 706
P + NK + LK+ CF+ +F P K N QV ++ + L G
Sbjct: 432 EVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKG 490
Query: 707 FSSRVTSRGLFKENNERCLQKNMVVNQA--QSCPEHIIYIQEPSDVVNSL-------DLR 757
R LF + KNM +++ C E I Y+++ S+ + L + R
Sbjct: 491 ----AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYR 546
Query: 758 VD--ISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFI 815
+D + + G P L ++ DCGED +C L ++ +Q I
Sbjct: 547 LDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL-----EVSVDSDQKKI 601
Query: 816 VSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKS-- 873
+ LT V +N+ E AY ++V A F V E +++ + K+
Sbjct: 602 YIGDDNPLTLIVKAQNQGEGAYEAELIVSIP---LQADFIGVVRNNEALARLSCAFKTEN 658
Query: 874 ----VACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLK 929
V CD+G P +K Q+ + F + Q+ + + + S +K +V+ K
Sbjct: 659 QTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHK 717
Query: 930 IPL--LYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGP--KFIFSLKVTTGSVPVS 985
+ L L EI S + F I + + + + EDVGP + I+ L+ + P S
Sbjct: 718 VDLAVLAAVEIRGVSSPDHIFLPIPNWEHKEN-PETEEDVGPVVQHIYELR---NNGPSS 773
Query: 986 MATVIIHIP-QYTKEKNPLMYLTGVQTDKAGDISCNAD--INPLKIGQTSSSVSFK---- 1038
+ ++H+ Y N L+Y+ D G ++C +D INPL+I +S + K
Sbjct: 774 FSKAMLHLQWPYKYNNNTLLYILHYDID--GPMNCTSDMEINPLRIKISSLQTTEKNDTV 831
Query: 1039 -----------------SENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWN 1081
SE HT L C A C + C + + + V + +W
Sbjct: 832 AGQGERDHLITKRDLALSEGDIHT--LGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWT 889
Query: 1082 GTFASSTFQ----TVQLTAAAEINTYNPEIYVIEDNT----VTIPLMIMKPDEKAEVPTG 1133
TF + Q +++ +A+ + + + IED T VT + VP
Sbjct: 890 ETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVW 949
Query: 1134 VIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTEL 1179
VII +++AG+LLL LV +++++GFFKR + P E E +L
Sbjct: 950 VIILAVLAGLLLLAVLVFVMYRMGFFKR-----VRPPQEEQEREQL 990
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 199 bits (507), Expect = 1e-50
Identities = 235/886 (26%), Positives = 386/886 (43%), Gaps = 121/886 (13%)
Query: 380 QVGFSADYSSQNDILMLGAVGAFGWSGTIVQKT----------SHGHLIFPKQAFDQILQ 429
Q GFS D++ + +L LG G+F W G ++ + + + Q + Q
Sbjct: 186 QGGFSIDFTKADRVL-LGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQ 244
Query: 430 DRNHSSYLGYSVAA--ISTGESTHFVAGAPRANYT-GQIVLYSVNENGNITVIQAHRGDQ 486
SYLGYSVA + FV+G PRA T G + +Y + N++ + G+Q
Sbjct: 245 AIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTGEQ 301
Query: 487 IGSYFGSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRVYLFTIKEGILGQHQF 542
+ +YFG + + D++ D DV +GAP++M SD K +E G+V + + Q
Sbjct: 302 MAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK 360
Query: 543 LEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQN-SGAVYIYNGHQGTIRTKYS 601
L G E RFGSAIA L D++ DGFND+ + +P ++ G VYI+NG + S
Sbjct: 361 LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPS 418
Query: 602 QKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG--QVVQLWSQSIADVAIEA 659
Q IL A RS FG S+ G D++ + D+ +GAFG + + ++ + V
Sbjct: 419 Q-ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGL 477
Query: 660 SFTPEKITLVNKNAQI---ILKL-CFSAKF---------RPTKQNNQVAIVYNITLDADG 706
P + NK + LK+ CF+ +F P K N QV ++ + L G
Sbjct: 478 EVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKG 536
Query: 707 FSSRVTSRGLFKENNERCLQKNMVVNQA--QSCPEHIIYIQEPSDVVNSL-------DLR 757
R LF + KNM +++ C E I Y+++ S+ + L + R
Sbjct: 537 ----AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYR 592
Query: 758 VD--ISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFI 815
+D + + G P L ++ DCGED +C L ++ +Q I
Sbjct: 593 LDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL-----EVSVDSDQKKI 647
Query: 816 VSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKS-- 873
+ LT V +N+ E AY ++V A F V E +++ + K+
Sbjct: 648 YIGDDNPLTLIVKAQNQGEGAYEAELIVSIP---LQADFIGVVRNNEALARLSCAFKTEN 704
Query: 874 ----VACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLK 929
V CD+G P +K Q+ + F + Q+ + + + S +K +V+ K
Sbjct: 705 QTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHK 763
Query: 930 IPL--LYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGP--KFIFSLKVTTGSVPVS 985
+ L L EI S + F I + + + + EDVGP + I+ L+ + P S
Sbjct: 764 VDLAVLAAVEIRGVSSPDHIFLPIPNWEHKEN-PETEEDVGPVVQHIYELR---NNGPSS 819
Query: 986 MATVIIHIP-QYTKEKNPLMYLTGVQTDKAGDISCNAD--INPLKIGQTSSSVSFK---- 1038
+ ++H+ Y N L+Y+ D G ++C +D INPL+I +S + K
Sbjct: 820 FSKAMLHLQWPYKYNNNTLLYILHYDID--GPMNCTSDMEINPLRIKISSLQTTEKNDTV 877
Query: 1039 -----------------SENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWN 1081
SE HT L C A C + C + + + V + +W
Sbjct: 878 AGQGERDHLITKRDLALSEGDIHT--LGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWT 935
Query: 1082 GTFASSTFQ----TVQLTAAAEINTYNPEIYVIEDNT----VTIPLMIMKPDEKAEVPTG 1133
TF + Q +++ +A+ + + + IED T VT + VP
Sbjct: 936 ETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVW 995
Query: 1134 VIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTEL 1179
VII +++AG+LLL LV +++++GFFKR + P E E +L
Sbjct: 996 VIILAVLAGLLLLAVLVFVMYRMGFFKR-----VRPPQEEQEREQL 1036
Score = 43.5 bits (101), Expect = 0.001
Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 18/156 (11%)
Query: 5 RTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGN--W 62
R G LPLLL S +L C A+N+ + +SGP FG+AV F+ + +
Sbjct: 10 RLGPRGLPLLL----SGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMF 65
Query: 63 LLVGSPWSGFPENRM---GDVYKCPVDLSTATCEKLNLQTS----TSIPNVTEMKTNMSL 115
LLVG+P + + + G V KC ST C+ + + + + E K++
Sbjct: 66 LLVGAPKANTTQPGIVEGGQVLKCDWS-STRRCQPIEFDATGNRDYAKDDPLEFKSHQWF 124
Query: 116 GLILTRNMGTGGFLTCGPL--WAQQCGNQYYTTGVC 149
G + L C PL W + + G C
Sbjct: 125 GASVRSKQDK--ILACAPLYHWRTEMKQEREPVGTC 158
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 189 bits (481), Expect = 1e-47
Identities = 221/821 (26%), Positives = 361/821 (43%), Gaps = 110/821 (13%)
Query: 435 SYLGYSVAA--ISTGESTHFVAGAPRANYT-GQIVLYSVNENGNITVIQAHRGDQIGSYF 491
SYLGYSVA + FV+G PRA T G + +Y + N++ + G+Q+ +YF
Sbjct: 214 SYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTGEQMAAYF 270
Query: 492 GSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRVYLFTIKEGILGQHQFLEGPE 547
G + + D++ D DV +GAP++M SD K +E G+V + + Q L G E
Sbjct: 271 GFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFE 329
Query: 548 GIENTRFGSAIAALSDINMDGFNDVIVGSPLENQN-SGAVYIYNGHQGTIRTKYSQKILG 606
RFGSAIA L D++ DGFND+ + +P ++ G VYI+NG + SQ IL
Sbjct: 330 VF--ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQ-ILE 386
Query: 607 SDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG--QVVQLWSQSIADVAIEASFTPE 664
A RS FG S+ G D++ + D+ +GAFG + + ++ + V P
Sbjct: 387 GQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS 446
Query: 665 KITLVNKNAQI---ILKL-CFSAKF---------RPTKQNNQVAIVYNITLDADGFSSRV 711
+ NK + LK+ CF+ +F P K N QV ++ + L G
Sbjct: 447 ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQKG----A 501
Query: 712 TSRGLFKENNERCLQKNMVVNQA--QSCPEHIIYIQEPSDVVNSL-------DLRVD--I 760
R LF + KNM +++ C E I Y+++ S+ + L + R+D
Sbjct: 502 IRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRT 561
Query: 761 SLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQN 820
+ + G P L ++ DCGED +C L ++ +Q I +
Sbjct: 562 AADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL-----EVSVDSDQKKIYIGDD 616
Query: 821 KRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKS------V 874
LT V +N+ E AY ++V A F V E +++ + K+ V
Sbjct: 617 NPLTLIVKAQNQGEGAYEAELIVSIP---LQADFIGVVRNNEALARLSCAFKTENQTRQV 673
Query: 875 ACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENKADNLVNLKIPL-- 932
CD+G P +K Q+ + F + Q+ + + + S +K +V+ K+ L
Sbjct: 674 VCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAV 732
Query: 933 LYDAEIHLTRSTNINFYEISSDGNVPSIVHSFEDVGP--KFIFSLKVTTGSVPVSMATVI 990
L EI S + F I + + + + EDVGP + I+ L+ + P S + +
Sbjct: 733 LAAVEIRGVSSPDHIFLPIPNWEHKEN-PETEEDVGPVVQHIYELR---NNGPSSFSKAM 788
Query: 991 IHIP-QYTKEKNPLMYLTGVQTDKAGDISCNAD--INPLKIGQTSSSVSFK--------- 1038
+H+ Y N L+Y+ D G ++C +D INPL+I +S + K
Sbjct: 789 LHLQWPYKYNNNTLLYILHYDID--GPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGE 846
Query: 1039 ------------SENFRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFAS 1086
SE HT L C A C + C + + + V + +W TF +
Sbjct: 847 RDHLITKRDLALSEGDIHT--LGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMN 904
Query: 1087 STFQ----TVQLTAAAEINTYNPEIYVIEDNT----VTIPLMIMKPDEKAEVPTGVIIGS 1138
Q +++ +A+ + + + IED T VT + VP VII +
Sbjct: 905 KENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILA 964
Query: 1139 IIAGILLLLALVAILWKLGFFKRKYEKMTKNPDEIDETTEL 1179
++AG+LLL LV +++++GFFKR + P E E +L
Sbjct: 965 VLAGLLLLAVLVFVMYRMGFFKR-----VRPPQEEQEREQL 1000
Score = 43.5 bits (101), Expect = 0.001
Identities = 42/156 (26%), Positives = 65/156 (41%), Gaps = 18/156 (11%)
Query: 5 RTGAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGN--W 62
R G LPLLL S +L C A+N+ + +SGP FG+AV F+ + +
Sbjct: 10 RLGPRGLPLLL----SGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMF 65
Query: 63 LLVGSPWSGFPENRM---GDVYKCPVDLSTATCEKLNLQTS----TSIPNVTEMKTNMSL 115
LLVG+P + + + G V KC ST C+ + + + + E K++
Sbjct: 66 LLVGAPKANTTQPGIVEGGQVLKCDWS-STRRCQPIEFDATGNRDYAKDDPLEFKSHQWF 124
Query: 116 GLILTRNMGTGGFLTCGPL--WAQQCGNQYYTTGVC 149
G + L C PL W + + G C
Sbjct: 125 GASVRSKQDK--ILACAPLYHWRTEMKQEREPVGTC 158
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 171 bits (434), Expect = 3e-42
Identities = 217/896 (24%), Positives = 367/896 (40%), Gaps = 125/896 (13%)
Query: 372 DNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGT--IVQKTSHGHLIFPKQAFDQILQ 429
D + M Q+G S ++ QN + GA GA+ W G ++Q+ + +
Sbjct: 190 DYLETGMCQLGTSGGFT-QNTVYF-GAPGAYNWKGNSYMIQRKE-----WDLSEYSYKDP 242
Query: 430 DRNHSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQ 486
+ + Y+GY++ I ++ V GAPR + G + L S G++ Q G Q
Sbjct: 243 EDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302
Query: 487 IGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGI---LGQHQFL 543
+G+YFGS + D++ D D LLVGAP Y ++ G +Y+F + G L
Sbjct: 303 VGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLL 361
Query: 544 EGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIY-NGHQGTIRTKYSQ 602
GP G + FG ++A++ DIN DGF D+ VG+P E G VYIY + +G +R Q
Sbjct: 362 HGPSG---SAFGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSKGLLR--QPQ 414
Query: 603 KILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG-QVVQLWSQSIADVAIEASF 661
+++ + L FG SL G D++ + D+ +G+ +V L ++ + ++ + +
Sbjct: 415 QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI-VHKTL 473
Query: 662 TPEKI----TLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDAD----------GF 707
P L + + ++LCF+ N + I TL+AD
Sbjct: 474 VPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAG 533
Query: 708 SSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGT 767
S G F RC + +++ I I + + R + L +
Sbjct: 534 SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA 593
Query: 768 SPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQ--PFIVSNQNKRLTF 825
P L + F K+CG D C S+L + + Q++ S ++L
Sbjct: 594 YPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLL 653
Query: 826 SVTLKNKR------ESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVG 879
S+ + N R E A+ + + L +S P CQ + +++ C++G
Sbjct: 654 SINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPP-----GACQ---ANETIFCELG 705
Query: 880 YPALKREQQVTFTINFD-----FNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLY 934
P KR Q++ I F+ + ++LQ Q LS + DNL + + LL
Sbjct: 706 NP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLS--------TSSHQDNLWPMILTLLV 756
Query: 935 DAEIHLTRSTNINFYEISSDGNV--PSIVHSFEDVGPKFIFSLKV-TTGSVPVSMATVII 991
D + + S + + G V S + + EDVG + +V G V + T+++
Sbjct: 757 DYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVL 816
Query: 992 HI--PQYTKEKNPLMYLTGVQTDKAGDISCNAD---INPLKI------------------ 1028
+ P L+Y T + G C INPL +
Sbjct: 817 GLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQ 876
Query: 1029 -----GQTSSSVSF-KSENFRHTKELNCRT--ASCSNVTCWLKDVHMKGEYFVNVTTRIW 1080
GQ V+ ++ + L C T A C + C + D + V V R+W
Sbjct: 877 LDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTN--VTVKARVW 934
Query: 1081 NGTFASS--TFQTVQLT--AAAEINTYNPEIYVIEDNTVTIPLMI---MKPDEKAEVPTG 1133
N TF F V++ A + T P I +E+ T + I + + AE+
Sbjct: 935 NSTFIEDYRDFDRVRVNGWATLFLRTSIPTIN-MENKTTWFSVDIDSELVEELPAEIELW 993
Query: 1134 VIIGSIIAGILLLLALVAILWKLGFFKRK-----YE------KMTKNPDEIDETTE 1178
+++ ++ AG+LLL ++ +LWK GFFKR YE +M P E + T+
Sbjct: 994 LVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAEMKSQPSETERLTD 1049
Score = 40.4 bits (93), Expect = 0.010
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 15/173 (8%)
Query: 2 GPERTGAAPLPLLLVLALSQGILNCCL-AYNVGLPEAKIF-SGPSSEQFGYAV---QQFI 56
GP R AP +L LAL C + A+N+ + +G FGY+V +Q
Sbjct: 4 GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63
Query: 57 NPKGNWLLVGSPWS-GFPE---NRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTN 112
+ LL G+P P+ NR G VY CP+ CE++N+ + + +
Sbjct: 64 RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGH--HIIED 121
Query: 113 MSLGLILTRNMGTGGFLTCGPLWAQ----QCGNQYYTTGVCSDISPDFQLSAS 161
M LG+ + G L C + Q +Q G C D +L +S
Sbjct: 122 MWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSS 174
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 169 bits (427), Expect = 2e-41
Identities = 213/881 (24%), Positives = 370/881 (41%), Gaps = 106/881 (12%)
Query: 368 VQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKT--------SHGHLIF 419
V+ ++ + GFS+ + + L+LGA G + + G + Q G L++
Sbjct: 187 VENDFSWDKRYCEAGFSSVVTQAGE-LVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLW 245
Query: 420 PKQAFDQILQDRNHSSYLGYSVAAISTGE------STHFVAGAPRANYT-GQI-VLYSVN 471
+ N + GY +++ GE +T +V GAP ++T G + +L S
Sbjct: 246 HVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYY 305
Query: 472 ENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRV 527
+ + RG+Q+ SYFG + DV+ D D LLVGAP+YM +D K E GRV
Sbjct: 306 QR-----LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRV 359
Query: 528 YLFTIKEG--ILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNS-G 584
YLF G LG L + RFGSAIA L D++ DG+ND+ V +P + G
Sbjct: 360 YLFLQPRGPHALGAPSLLLTGTQLYG-RFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRG 418
Query: 585 AVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG-- 642
V ++ G +R++ SQ + D F + FG SL G D++ + D+ +GA+G
Sbjct: 419 QVLVFLGQSEGLRSRPSQVL---DSPFPTG-SAFGFSLRGAVDIDDNGYPDLIVGAYGAN 474
Query: 643 QV------------VQLWSQSIADVAIEASFTPEKITLVNKNAQIILKLCFSAKFRPTKQ 690
QV VQL Q + A+++ P+ T V+ +++C A T
Sbjct: 475 QVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSC---FNIQMCVGA----TGH 527
Query: 691 NNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQS--CPEHIIYIQEPS 748
N + N L D R R L + + N+ + S C + ++++ +
Sbjct: 528 NIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEA 587
Query: 749 DVVNSLD-----LRVDISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDV 803
D + L L V + G +PA+ + +T DCGED +C+ L L
Sbjct: 588 DFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTA 647
Query: 804 RQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTE- 862
+ P +V N L + N+ E AY + V + + V+G E
Sbjct: 648 ----SVTGSPLLVGADNV-LELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFER 702
Query: 863 VTCQVAASQKS--VACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEEN 920
+ C ++ V C++G P K Q + NL+ S Q S++ + N
Sbjct: 703 LICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQ-N 761
Query: 921 KADNLVNLKIPLLYDAEIHLT-RSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKV-T 978
+V L +P+ +A++ L S + + +G +S + GPK + ++
Sbjct: 762 PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQ--NSLDSWGPKVEHTYELHN 819
Query: 979 TGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISC--NADINPLKIGQ----TS 1032
G V+ + IH+P ++ + L+Y+ +Q G + C +NPLK+ S
Sbjct: 820 NGPGTVNGLHLSIHLPGQSQPSD-LLYILDIQPQ--GGLQCFPQPPVNPLKVDWGLPIPS 876
Query: 1033 SSVSFKSENFRHTKEL-----------------NCRTASCSNVTCWLKDVHMKGEYFVNV 1075
S + + R +++ +C +A C+ V C L+++ V V
Sbjct: 877 PSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV 936
Query: 1076 TTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYV----IEDNTVTIPLMIMKPDEKAEVP 1131
+W + L + A N + V + + +++ E+ +P
Sbjct: 937 LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIP 996
Query: 1132 TGVIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDE 1172
++ ++ G+LLL LV +WK+GFFKR + ++ +E
Sbjct: 997 IWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 168 bits (426), Expect = 2e-41
Identities = 213/877 (24%), Positives = 361/877 (41%), Gaps = 116/877 (13%)
Query: 372 DNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGT--IVQKTSHGHLIFPKQAFDQILQ 429
D + M Q+G S ++ QN + GA GA+ W G ++Q+ + +
Sbjct: 190 DYLETGMCQLGTSGGFT-QNTVYF-GAPGAYNWKGNSYMIQRKE-----WDLSEYSYKDP 242
Query: 430 DRNHSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQ 486
+ + Y+GY++ I ++ V GAPR + G + L S G++ Q G Q
Sbjct: 243 EDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302
Query: 487 IGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGI---LGQHQFL 543
+G+YFGS + D++ D D LLVGAP Y ++ G +Y+F + G L
Sbjct: 303 VGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLL 361
Query: 544 EGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIY-NGHQGTIRTKYSQ 602
GP G + FG ++A++ DIN DGF D+ VG+P E G VYIY + +G +R Q
Sbjct: 362 HGPSG---SAFGLSVASIGDINQDGFQDIAVGAPFE--GLGKVYIYHSSSKGLLR--QPQ 414
Query: 603 KILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG-QVVQLWSQSIADVAIEASF 661
+++ + L FG SL G D++ + D+ +G+ +V L ++ + ++ + +
Sbjct: 415 QVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI-VHKTL 473
Query: 662 TPEKI----TLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNITLDAD----------GF 707
P L + + ++LCF+ N + I TL+AD
Sbjct: 474 VPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAG 533
Query: 708 SSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGT 767
S G F RC + +++ I I + + R + L +
Sbjct: 534 SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDA 593
Query: 768 SPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQ--PFIVSNQNKRLTF 825
P L + F K+CG D C S+L + + Q++ S ++L
Sbjct: 594 YPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLL 653
Query: 826 SVTLKNKR------ESAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVG 879
S+ + N R E A+ + + L +S P CQ + +++ C++G
Sbjct: 654 SINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPP-----GACQ---ANETIFCELG 705
Query: 880 YPALKREQQVTFTINFD-----FNLQNLQNQASLSFQALSESQEENKADNLVNLKIPLLY 934
P KR Q++ I F+ + ++LQ Q LS + DNL + + LL
Sbjct: 706 NP-FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLS--------TSSHQDNLWPMILTLLV 756
Query: 935 DAEIHLTRSTNINFYEISSDGNV--PSIVHSFEDVGPKFIFSLKV-TTGSVPVSMATVII 991
D + + S + + G V S + + EDVG + +V G V + T+++
Sbjct: 757 DYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVL 816
Query: 992 HI--PQYTKEKNPLMYLTGVQTDKAGDISCNAD---INPLKI------------------ 1028
+ P L+Y T + G C INPL +
Sbjct: 817 GLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQ 876
Query: 1029 -----GQTSSSVSF-KSENFRHTKELNCRT--ASCSNVTCWLKDVHMKGEYFVNVTTRIW 1080
GQ V+ ++ + L C T A C + C + D + V V R+W
Sbjct: 877 LDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTN--VTVKARVW 934
Query: 1081 NGTFASS--TFQTVQLT--AAAEINTYNPEIYVIEDNTVTIPLMI---MKPDEKAEVPTG 1133
N TF F V++ A + T P I +E+ T + I + + AE+
Sbjct: 935 NSTFIEDYRDFDRVRVNGWATLFLRTSIPTIN-MENKTTWFSVDIDSELVEELPAEIELW 993
Query: 1134 VIIGSIIAGILLLLALVAILWKLGFFKRK--YEKMTK 1168
+++ ++ AG+LLL ++ +LWK FFKR Y+ M K
Sbjct: 994 LVLVAVGAGLLLLGLIILLLWKCDFFKRTRYYQIMPK 1030
Score = 40.4 bits (93), Expect = 0.010
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 15/173 (8%)
Query: 2 GPERTGAAPLPLLLVLALSQGILNCCL-AYNVGLPEAKIF-SGPSSEQFGYAV---QQFI 56
GP R AP +L LAL C + A+N+ + +G FGY+V +Q
Sbjct: 4 GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63
Query: 57 NPKGNWLLVGSPWS-GFPE---NRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTN 112
+ LL G+P P+ NR G VY CP+ CE++N+ + + +
Sbjct: 64 RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGH--HIIED 121
Query: 113 MSLGLILTRNMGTGGFLTCGPLWAQ----QCGNQYYTTGVCSDISPDFQLSAS 161
M LG+ + G L C + Q +Q G C D +L +S
Sbjct: 122 MWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSS 174
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 149 bits (375), Expect = 2e-35
Identities = 157/622 (25%), Positives = 268/622 (43%), Gaps = 84/622 (13%)
Query: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSG----TIVQKTSHGHLIF- 419
EG QG + F Q G +A +S + L+ GA G + W G T + + L++
Sbjct: 185 EGRPQGHEQFGF--CQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYK 242
Query: 420 ---PKQAFDQILQDRNHSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYSVNEN 473
P D +SYLG+S+ + + E FVAGAPRAN+ G +V+ +
Sbjct: 243 TLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSA 302
Query: 474 GNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIK 533
+ G+++ S FG L D++ D D L+VGAP + ++ G VY++ +
Sbjct: 303 SRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYLNQ 361
Query: 534 EGILGQHQFLEGPE---GIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYN 590
G H P G ++ FG ++A L D+N DGF D+ VG+P + G V+IY+
Sbjct: 362 GG----HWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFD--GDGKVFIYH 415
Query: 591 GHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLW-S 649
G + K SQ + G +S FG SL G D++G+ D+ +G+ L+ +
Sbjct: 416 GSSLGVVAKPSQVLEGEAVGIKS----FGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRA 471
Query: 650 QSIADVAIEASFTPEKITLVNKNAQ------IILKLCFSAKFRPTKQNNQVAIVYNITLD 703
+ I V+ E S P I L N + L++CFS P+ + VA+ Y + D
Sbjct: 472 RPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDAD 531
Query: 704 AD----GFSSRVT--SRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVNSLDL 756
D G RVT SR L + ++ + + C + + +QE D + ++ +
Sbjct: 532 TDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVV 591
Query: 757 RVDISLEN------------PGTSPALEAYSETAKVFSIPFHKD-CGEDGLCISDLVLDV 803
+ SL+ P +P L A+ + + I F K CGED +C S+L L V
Sbjct: 592 TLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL-V 650
Query: 804 R-----QIPAAQEQPFIVSNQNKRLTFSVT--------------------LKNKRESAYN 838
R ++ + QP + F+++ + + A+
Sbjct: 651 RARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHE 710
Query: 839 TGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTI---NF 895
++V ++L ++ + C + V C++G P +KR QVTF +
Sbjct: 711 AQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLILSTS 769
Query: 896 DFNLQNLQNQASLSFQALSESQ 917
+++ + + L +SE +
Sbjct: 770 GISIETTELEVELLLATISEQE 791
Score = 53.1 bits (126), Expect = 1e-06
Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 10/117 (8%)
Query: 1052 TASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFAS--STFQTVQLTAAAEINTYNP-EIY 1108
TA+C +C L ++V R+WN TF S +++++ A I + +
Sbjct: 954 TANCVVFSCPLYSFDRAA--VLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 1011
Query: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV----IIGSIIAGILLLLALVAILWKLGFFKR 1161
++ D + IP+M+ D A V GV I+ +++AG+L+L LV +LWK+GFFKR
Sbjct: 1012 MLRDASTVIPVMVYL-DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1067
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 145 bits (367), Expect = 2e-34
Identities = 159/626 (25%), Positives = 270/626 (43%), Gaps = 88/626 (14%)
Query: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTI-VQKTSHGHLIF---- 419
EG QG + F Q G +A +S + L+ GA G + W GT V+ + G
Sbjct: 88 EGRPQGHEQFGF--CQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLD 145
Query: 420 --PKQAFDQILQDRN-----HSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYS 469
P +A + QD +SY G+S+ + + E FVAGAPRAN+ G +V+
Sbjct: 146 DGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILR 205
Query: 470 VNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYL 529
+ + G+++ S FG L D++ D D L+VGAP + ++ G VY+
Sbjct: 206 KDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYV 264
Query: 530 FTIKEGILGQHQFLEGPE---GIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAV 586
+ + G H P G ++ FG ++A L D+N DGF D+ VG+P + G V
Sbjct: 265 YLNQGG----HWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFD--GDGKV 318
Query: 587 YIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQ 646
+IY+G + K SQ + G +S FG SL G D++G+ D+ +G+
Sbjct: 319 FIYHGSSLGVVAKPSQVLEGEAVGIKS----FGYSLSGSLDMDGNQYPDLLVGSLADTAV 374
Query: 647 LW-SQSIADVAIEASFTPEKITLVNKNAQ------IILKLCFSAKFRPTKQNNQVAIVYN 699
L+ ++ I V+ E S P I L N + L++CFS P+ + VA+ Y
Sbjct: 375 LFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYV 434
Query: 700 ITLDAD----GFSSRVT--SRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVN 752
+ D D G RVT SR L + ++ + + C + + +QE D +
Sbjct: 435 LDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLR 494
Query: 753 SLDLRVDISLEN------------PGTSPALEAYSETAKVFSIPFHKD-CGEDGLCISDL 799
++ + + SL+ P +P L A+ + + I F K CGED +C S+L
Sbjct: 495 AIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNL 554
Query: 800 VLDVR-----QIPAAQEQPFIVSNQNKRLTFSVT--------------------LKNKRE 834
L VR ++ + QP + F+++ + +
Sbjct: 555 QL-VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGD 613
Query: 835 SAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTI- 893
A+ ++V ++L ++ + C + V C++G P +KR QVTF +
Sbjct: 614 DAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLI 672
Query: 894 --NFDFNLQNLQNQASLSFQALSESQ 917
+++ + + L +SE +
Sbjct: 673 LSTSGISIETTELEVELLLATISEQE 698
Score = 53.1 bits (126), Expect = 1e-06
Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 10/117 (8%)
Query: 1052 TASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFAS--STFQTVQLTAAAEINTYNP-EIY 1108
TA+C +C L ++V R+WN TF S +++++ A I + +
Sbjct: 861 TANCVVFSCPLYSFDRAA--VLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 918
Query: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV----IIGSIIAGILLLLALVAILWKLGFFKR 1161
++ D + IP+M+ D A V GV I+ +++AG+L+L LV +LWK+GFFKR
Sbjct: 919 MLRDASTVIPVMVYL-DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 974
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 145 bits (367), Expect = 2e-34
Identities = 159/626 (25%), Positives = 270/626 (43%), Gaps = 88/626 (14%)
Query: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTI-VQKTSHGHLIF---- 419
EG QG + F Q G +A +S + L+ GA G + W GT V+ + G
Sbjct: 185 EGRPQGHEQFGF--CQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLD 242
Query: 420 --PKQAFDQILQDRN-----HSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYS 469
P +A + QD +SY G+S+ + + E FVAGAPRAN+ G +V+
Sbjct: 243 DGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILR 302
Query: 470 VNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYL 529
+ + G+++ S FG L D++ D D L+VGAP + ++ G VY+
Sbjct: 303 KDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYV 361
Query: 530 FTIKEGILGQHQFLEGPE---GIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAV 586
+ + G H P G ++ FG ++A L D+N DGF D+ VG+P + G V
Sbjct: 362 YLNQGG----HWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFD--GDGKV 415
Query: 587 YIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQ 646
+IY+G + K SQ + G +S FG SL G D++G+ D+ +G+
Sbjct: 416 FIYHGSSLGVVAKPSQVLEGEAVGIKS----FGYSLSGSLDMDGNQYPDLLVGSLADTAV 471
Query: 647 LW-SQSIADVAIEASFTPEKITLVNKNAQ------IILKLCFSAKFRPTKQNNQVAIVYN 699
L+ ++ I V+ E S P I L N + L++CFS P+ + VA+ Y
Sbjct: 472 LFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYV 531
Query: 700 ITLDAD----GFSSRVT--SRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVN 752
+ D D G RVT SR L + ++ + + C + + +QE D +
Sbjct: 532 LDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLR 591
Query: 753 SLDLRVDISLEN------------PGTSPALEAYSETAKVFSIPFHKD-CGEDGLCISDL 799
++ + + SL+ P +P L A+ + + I F K CGED +C S+L
Sbjct: 592 AIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNL 651
Query: 800 VLDVR-----QIPAAQEQPFIVSNQNKRLTFSVT--------------------LKNKRE 834
L VR ++ + QP + F+++ + +
Sbjct: 652 QL-VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGD 710
Query: 835 SAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTI- 893
A+ ++V ++L ++ + C + V C++G P +KR QVTF +
Sbjct: 711 DAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLI 769
Query: 894 --NFDFNLQNLQNQASLSFQALSESQ 917
+++ + + L +SE +
Sbjct: 770 LSTSGISIETTELEVELLLATISEQE 795
Score = 53.1 bits (126), Expect = 1e-06
Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 10/117 (8%)
Query: 1052 TASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFAS--STFQTVQLTAAAEINTYNP-EIY 1108
TA+C +C L ++V R+WN TF S +++++ A I + +
Sbjct: 958 TANCVVFSCPLYSFDRAA--VLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 1015
Query: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV----IIGSIIAGILLLLALVAILWKLGFFKR 1161
++ D + IP+M+ D A V GV I+ +++AG+L+L LV +LWK+GFFKR
Sbjct: 1016 MLRDASTVIPVMVYL-DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 90.1 bits (222), Expect = 1e-17
Identities = 55/180 (30%), Positives = 100/180 (55%), Gaps = 17/180 (9%)
Query: 170 PSLIDVVVVCDESNSI--YPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLN 227
P++ D+V++ D S SI + + V++FLE V D+G KT++GL QY+ +PR+ ++LN
Sbjct: 154 PAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLN 213
Query: 228 TYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESH 287
+ TK+E+I A GG+ T T A+ Y + ++ +G R +K+ +++TDG+S
Sbjct: 214 AFSTKDEVIEAVRNLPYKGGN-TLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQ 272
Query: 288 DGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNL-IKEIKAIASIPTERYFFNVSD 346
D + + N+ G+ + A+ KN + E++ IAS P + +NV++
Sbjct: 273 DDIIPPS-------RNLRESGVELF------AIGVKNADVNELQEIASEPDSTHVYNVAE 319
Score = 86.7 bits (213), Expect = 1e-16
Identities = 66/187 (35%), Positives = 96/187 (51%), Gaps = 17/187 (9%)
Query: 164 PATQPCPSL-IDVVVVCDESNSIYP--WDAVKNFLEKFVQGLD-IGPTKTQVGLIQYANN 219
PA + C + D+V + D S SI ++ + +FL V L+ IG TQV ++Q+ ++
Sbjct: 1021 PAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDD 1080
Query: 220 PRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMV 279
PR F LN YKTKE ++ A S GG+ T T AI+Y R ++A SG RR KV+V
Sbjct: 1081 PRTEFKLNAYKTKETLLDAIKHISYKGGN-TKTGKAIKYVRDTLFTAESGTRRGIPKVIV 1139
Query: 280 VVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTER 339
V+TDG S D + Q + +I G+A Y E+ +I S P+ R
Sbjct: 1140 VITDGRSQDDVNKISREMQLDGYSIFAIGVADADY------------SELVSIGSKPSAR 1187
Query: 340 YFFNVSD 346
+ F V D
Sbjct: 1188 HVFFVDD 1194
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor
[Homo sapiens]
Length = 3063
Score = 86.3 bits (212), Expect = 2e-16
Identities = 60/192 (31%), Positives = 100/192 (52%), Gaps = 15/192 (7%)
Query: 174 DVVVVCDESNSI--YPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKT 231
D+V + D S S+ + + +F+ V DIG KT+VG++QY+++ R FNLN Y
Sbjct: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQ 199
Query: 232 KEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSM 291
++E++ A + GG+ T T AI Y K ++ ++G R KV +++TDG+S D
Sbjct: 200 RDELLAAIKKIPYKGGN-TMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVE 258
Query: 292 LKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALL 351
+ A + G+ V L A D KE+K IAS P+ + FNV++ A++
Sbjct: 259 IPA-------RELRNVGVEVFS-LGIKAADA----KELKQIASTPSLNHVFNVANFDAIV 306
Query: 352 EKAGTLGEQIFS 363
+ + Q+ S
Sbjct: 307 DIQNEIISQVCS 318
Score = 84.7 bits (208), Expect = 5e-16
Identities = 58/176 (32%), Positives = 91/176 (51%), Gaps = 17/176 (9%)
Query: 174 DVVVVCDESNSIYPWDAVK--NFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKT 231
D+V + D S SI + VK FLE V+ +I P + Q+ L+QY+ +P F L + T
Sbjct: 440 DIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKF-T 498
Query: 232 KEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSM 291
K E I+ T Y G TNT A+ Y R+ + + G R + KVM+++TDG+S D
Sbjct: 499 KVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFR 558
Query: 292 LKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIK-EIKAIASIPTERYFFNVSD 346
A+ + + ++ F + V K+ ++ E++AIAS P E + F V D
Sbjct: 559 DPAI--KLRNSDVEIFAVGV-----------KDAVRSELEAIASPPAETHVFTVED 601
Score = 79.7 bits (195), Expect = 1e-14
Identities = 53/179 (29%), Positives = 98/179 (54%), Gaps = 15/179 (8%)
Query: 174 DVVVVCDESNSI--YPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKT 231
D+V++ D S SI + V++F+ + V+ DIGP + Q+ L QY+ +PR + LN ++
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
Query: 232 KEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSM 291
K+ ++ A + GG+ T T A+ + R+ + +G R A K+ V++TDG+S D
Sbjct: 1259 KKSLLQAVANLPYKGGN-TLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDD-- 1315
Query: 292 LKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAAL 350
++A + + + F I + +NA + E+K IA+ P + + +NV+D +L
Sbjct: 1316 VEAPSKKLKDEGVELFAIGI-----KNADEV-----ELKMIATDPDDTHAYNVADFESL 1364
Score = 75.9 bits (185), Expect = 2e-13
Identities = 60/187 (32%), Positives = 90/187 (48%), Gaps = 17/187 (9%)
Query: 164 PATQPCPSL-IDVVVVCDESNSIYP--WDAVKNFLEKFVQGLD-IGPTKTQVGLIQYANN 219
PA C D+V + D S SI ++ V F+ V G D I P QV +QY++
Sbjct: 2312 PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDE 2371
Query: 220 PRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMV 279
+ F LNTY K + + Q +Y G T T A+ + ++ + SG R++ KV+V
Sbjct: 2372 VKSEFKLNTYNDKA-LALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLV 2430
Query: 280 VVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTER 339
VVTDG S D A++ Q + ++ G+A + Y E+ IAS P+ER
Sbjct: 2431 VVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDY------------NELANIASKPSER 2478
Query: 340 YFFNVSD 346
+ F V D
Sbjct: 2479 HVFIVDD 2485
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 80.1 bits (196), Expect = 1e-14
Identities = 59/179 (32%), Positives = 91/179 (50%), Gaps = 17/179 (9%)
Query: 174 DVVVVCDESNSIYP--WDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKT 231
D+V + D S S+ P ++ VK +L + DIGP QVG++QY++ P + L +Y +
Sbjct: 37 DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96
Query: 232 KEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSM 291
E + A GG+ T T AIQ+A Y ++ +S R TK+ VV+TDG+S D
Sbjct: 97 GEHLTAAVESILYLGGN-TKTGKAIQFALDYLFAKSS---RFLTKIAVVLTDGKSQDD-- 150
Query: 292 LKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAAL 350
+K I F I V +T++ E++AIA+ P+ Y F V D A+
Sbjct: 151 VKDAAQAARDSKITLFAIGV-------GSETED--AELRAIANKPSSTYVFYVEDYIAI 200
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 79.7 bits (195), Expect = 1e-14
Identities = 53/179 (29%), Positives = 98/179 (54%), Gaps = 15/179 (8%)
Query: 174 DVVVVCDESNSI--YPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKT 231
D+V++ D S SI + V++F+ + V+ DIGP + Q+ L QY+ +PR + LN ++
Sbjct: 35 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 94
Query: 232 KEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSM 291
K+ ++ A + GG+ T T A+ + R+ + +G R A K+ V++TDG+S D
Sbjct: 95 KKSLLQAVANLPYKGGN-TLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDD-- 151
Query: 292 LKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAAL 350
++A + + + F I + +NA + E+K IA+ P + + +NV+D +L
Sbjct: 152 VEAPSKKLKDEGVELFAIGI-----KNADEV-----ELKMIATDPDDTHAYNVADFESL 200
Score = 75.9 bits (185), Expect = 2e-13
Identities = 60/187 (32%), Positives = 90/187 (48%), Gaps = 17/187 (9%)
Query: 164 PATQPCPSL-IDVVVVCDESNSIYP--WDAVKNFLEKFVQGLD-IGPTKTQVGLIQYANN 219
PA C D+V + D S SI ++ V F+ V G D I P QV +QY++
Sbjct: 1148 PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDE 1207
Query: 220 PRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMV 279
+ F LNTY K + + Q +Y G T T A+ + ++ + SG R++ KV+V
Sbjct: 1208 VKSEFKLNTYNDKA-LALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLV 1266
Query: 280 VVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTER 339
VVTDG S D A++ Q + ++ G+A + Y E+ IAS P+ER
Sbjct: 1267 VVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDY------------NELANIASKPSER 1314
Query: 340 YFFNVSD 346
+ F V D
Sbjct: 1315 HVFIVDD 1321
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,771,760
Number of Sequences: 37866
Number of extensions: 1826472
Number of successful extensions: 4292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3796
Number of HSP's gapped (non-prelim): 165
length of query: 1181
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1068
effective length of database: 13,968,660
effective search space: 14918528880
effective search space used: 14918528880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.