Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 23510410
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
(506 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 1037 0.0
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 944 0.0
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 698 0.0
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 464 e-130
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 238 1e-62
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 236 3e-62
gi|166064021 solute carrier family 22 (organic anion transporter... 220 2e-57
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 214 1e-55
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 211 2e-54
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 209 4e-54
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 209 4e-54
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 209 4e-54
gi|31542327 solute carrier family 22, member 16 [Homo sapiens] 201 2e-51
gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 193 3e-49
gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens] 192 5e-49
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 180 2e-45
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 180 3e-45
gi|211059435 solute carrier family 22, member 24 [Homo sapiens] 176 4e-44
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 175 1e-43
gi|157426885 organic cation transporter like 4 [Homo sapiens] 174 1e-43
gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 164 2e-40
gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 159 4e-39
gi|153791484 putative UST1-like organic anion transporter [Homo ... 137 2e-32
gi|42542386 solute carrier family 22 (organic anion/cation trans... 133 4e-31
gi|24308167 SV2 related protein [Homo sapiens] 123 3e-28
gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens] 110 3e-24
gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6... 108 9e-24
gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1... 106 6e-23
gi|63999576 solute carrier family 22, member 17 isoform b [Homo ... 103 4e-22
gi|170650643 solute carrier family 22, member 23 isoform a [Homo... 99 9e-21
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 1037 bits (2682), Expect = 0.0
Identities = 506/506 (100%), Positives = 506/506 (100%)
Query: 1 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ 60
MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
Sbjct: 1 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ 60
Query: 61 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP 120
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
Sbjct: 61 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP 120
Query: 121 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL 180
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
Sbjct: 121 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL 180
Query: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY 240
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
Sbjct: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY 240
Query: 241 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK 300
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
Sbjct: 241 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK 300
Query: 301 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL 360
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
Sbjct: 301 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL 360
Query: 361 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM 420
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
Sbjct: 361 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM 420
Query: 421 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPACRGSDATSSRDQG 480
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPACRGSDATSSRDQG
Sbjct: 421 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPACRGSDATSSRDQG 480
Query: 481 GRFARDHEGRREPWEKSKAQRKHDLP 506
GRFARDHEGRREPWEKSKAQRKHDLP
Sbjct: 481 GRFARDHEGRREPWEKSKAQRKHDLP 506
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 944 bits (2441), Expect = 0.0
Identities = 462/465 (99%), Positives = 463/465 (99%)
Query: 1 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ 60
MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
Sbjct: 1 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ 60
Query: 61 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP 120
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP
Sbjct: 61 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP 120
Query: 121 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL 180
CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL
Sbjct: 121 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL 180
Query: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY 240
GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY
Sbjct: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY 240
Query: 241 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK 300
QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK
Sbjct: 241 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK 300
Query: 301 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL 360
IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL
Sbjct: 301 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL 360
Query: 361 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM 420
YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM
Sbjct: 361 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM 420
Query: 421 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFV +G
Sbjct: 421 IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLG 465
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 698 bits (1801), Expect = 0.0
Identities = 329/463 (71%), Positives = 378/463 (81%)
Query: 3 TVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRC 62
TVDD+LE GE +FQKQ F +L LLSA FAPI VGIVFLGFTPDH C+SPGVAELS RC
Sbjct: 4 TVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHRCRSPGVAELSLRC 63
Query: 63 GWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQ 122
GWSPAEELNYTVPG GPAGEA QCRRYEVDWNQS CVDPLASL TNRS LPLGPC+
Sbjct: 64 GWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCR 123
Query: 123 DGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGT 182
DGWVY+TPGSSIVTEFNLVCA+SW LDLFQS +N GF GS+ +GY ADRFGRKLCLL T
Sbjct: 124 DGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTT 183
Query: 183 VLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQM 242
VL+NA +GVLMA SP Y ML+FRL+QGLVSK W+ GY LITEFVG RRTV I YQ+
Sbjct: 184 VLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTVGIFYQV 243
Query: 243 AFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIM 302
A+TVGL+ L G+AYALPHWRWLQ V+LP F FLLYYWC+PESPRWL+SQ +N EA++I+
Sbjct: 244 AYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAMRII 303
Query: 303 DHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQ 362
HIA+KNGK PA L+ L LEE+ +KL+PSF DL RTP++RK T ILMY WFT SVLYQ
Sbjct: 304 KHIAKKNGKSLPASLQRLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFTSSVLYQ 363
Query: 363 GLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIF 422
GLI+HMG N+YLDF YSALVE P AF+ ++TIDR+GR YP A SN++AGAACL +F
Sbjct: 364 GLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGAACLASVF 423
Query: 423 ISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
I DL WL III C+GRMGIT+A +++CLVNAELYPTF+ +G
Sbjct: 424 IPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLG 466
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 464 bits (1193), Expect = e-130
Identities = 232/479 (48%), Positives = 330/479 (68%), Gaps = 13/479 (2%)
Query: 1 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHH-CQSPGVAELS 59
MP+ D+ L++VGE G FQ++ FL+LCL FA + VG+VFLG PDH+ C+ P A L+
Sbjct: 1 MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALA 60
Query: 60 QRCGWSPAEELNYTVPGL-GPAGEAFLGQCRRYEVDWNQ------SALSCVDPLASLATN 112
+RCGWSP EE N T P GP G+C+RY ++ SALSC DPLA+ N
Sbjct: 61 ERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFP-N 119
Query: 113 RSHLPLGPCQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADR 172
RS PL PC+ GW Y S+IV+EF+LVC ++W LDL Q+ LN GFL G+ +GY ADR
Sbjct: 120 RS-APLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADR 178
Query: 173 FGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGS 232
+GR + L + L V+GV++AF+PN+ ++FR LQG+ KG WM Y ++TE VGS
Sbjct: 179 YGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQ 238
Query: 233 RRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQ 292
RR V I+ QM FT+G++ L G+AY +P+W+ +QLA++LP+FLFLLYYW VPESPRWL+++
Sbjct: 239 RRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITR 298
Query: 293 KRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMY 352
K+ +A++I+ IA+ NGK ++ +++ ++ E +PSF DL RTP++RK T ILM+
Sbjct: 299 KKGDKALQILRRIAKCNGKYLSSNYSEITVTDE--EVSNPSFLDLVRTPQMRKCTLILMF 356
Query: 353 LWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLL 412
WFT +V+YQGL++ +G GNLY+DF S +VE+PGA + L+TI+R+GR P A SN++
Sbjct: 357 AWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIV 416
Query: 413 AGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPA-CRG 470
AG ACLV F+ + WL + +GR+GIT+A +++ LVN+ELYPT + G + C G
Sbjct: 417 AGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSG 475
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 238 bits (606), Expect = 1e-62
Identities = 173/489 (35%), Positives = 251/489 (51%), Gaps = 30/489 (6%)
Query: 1 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAP---ICVGIVFLGFTPDHHCQSPGVAE 57
M D++ +GE G FQ+ LI LLSA+ P + VFL TP+H C+ P A
Sbjct: 1 MRDYDEVTAFLGEWGPFQR---LIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAAN 57
Query: 58 LSQRCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDW--NQSALSCVDPLASLATNRSH 115
LS W N+TVP G CRRY + N SAL ++P + +
Sbjct: 58 LSS--AWR-----NHTVPLRLRDGREVPHSCRRYRLATIANFSALG-LEPGRDV--DLGQ 107
Query: 116 LPLGPCQDGWVY--DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRF 173
L C DGW + D S+IVTE+NLVC D WK L S G L GS G +DRF
Sbjct: 108 LEQESCLDGWEFSQDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRF 167
Query: 174 GRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSR 233
GRK L T+ + L FS N+ ++ +L G+ N++A + L TE +G R
Sbjct: 168 GRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVR 227
Query: 234 ---RTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLL 290
T+ + AF G + L AY + WR L +A+++P L + +W +PESPRWL+
Sbjct: 228 IIFSTLGVCIFYAF--GYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLI 285
Query: 291 SQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPS--FADLFRTPRLRKRTF 348
SQ R EA I+ A+ NG + P+ + S +D++ K S DL RT +R T
Sbjct: 286 SQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTI 345
Query: 349 ILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAM 408
+ + LW T SV Y GL L G+++++ SA+VE+P +A + + + R Y MA
Sbjct: 346 MSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMAT 405
Query: 409 SNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPAC 468
+ L G+ L M + PDL++L +++ VG+ G+T A M+ + AELYPT V +G
Sbjct: 406 ALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGV-- 463
Query: 469 RGSDATSSR 477
G +T+SR
Sbjct: 464 -GVSSTASR 471
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 236 bits (603), Expect = 3e-62
Identities = 156/469 (33%), Positives = 234/469 (49%), Gaps = 31/469 (6%)
Query: 3 TVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRC 62
T +IL++VG G FQ IL L A + +F TP HHC+ P A
Sbjct: 2 TFSEILDRVGSMGHFQFLHVAILGLPILNMANHNLLQIFTAATPVHHCRPPHNASTGP-- 59
Query: 63 GWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQ 122
+ +P +GP G+ +C R+ V P + N + + PC
Sbjct: 60 ---------WVLP-MGPNGKP--ERCLRF-----------VHPPNASLPNDTQRAMEPCL 96
Query: 123 DGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGT 182
DGWVY++ SIVTE++LVC + ++ QS AG L G L +G +DRFGR+ L +
Sbjct: 97 DGWVYNSTKDSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVLGDLSDRFGRRPILTCS 156
Query: 183 VLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQM 242
L+ A SG AFSP + ++FR L G G ++ L E+V + R ++
Sbjct: 157 YLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVEWVPTRMRAIMSTALGY 216
Query: 243 AFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIM 302
+T G L GLAYA+P WRWLQL VS+P F+F L W PES RWL+ ++++A+KI+
Sbjct: 217 CYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPESIRWLVLSGKSSKALKIL 276
Query: 303 DHIAQKNGK------LPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT 356
+A NGK L +LK+ +E K + +DLFR P LR+ TF L WF
Sbjct: 277 RRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIPMLRRMTFCLSLAWFA 336
Query: 357 DSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAA 416
Y L + + NLY+ + V++P FI ++++ +GR A + LLAG A
Sbjct: 337 TGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLGRHTTQAAALLLAGGA 396
Query: 417 CLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
L + F+ DL + ++ G+ ++ + + L +ELYPT + G
Sbjct: 397 ILALTFVPLDLQTVRTVLAVFGKGCLSSSFSCLFLYTSELYPTVIRQTG 445
>gi|166064021 solute carrier family 22 (organic anion transporter),
member 13 [Homo sapiens]
Length = 551
Score = 220 bits (561), Expect = 2e-57
Identities = 153/463 (33%), Positives = 226/463 (48%), Gaps = 21/463 (4%)
Query: 7 ILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCGWSP 66
+L ++G+ G FQ Q ++LC+L+ VF+ HHC V + S
Sbjct: 7 VLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVK--NHTFNLSA 64
Query: 67 AEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGWV 126
AE+L +VP L AG C + A + + + S N + PC GW
Sbjct: 65 AEQLVLSVP-LDTAGHP--EPCLMFRPP---PANASLQDILSHRFNETQ----PCDMGWE 114
Query: 127 Y-DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLV 185
Y + S+ EFNLVC D QS AG L G+L G DR GRK +L +L+
Sbjct: 115 YPENRLPSLKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLL 174
Query: 186 NAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFT 245
+ G+ AF P++ + R G + TL+TE+VG R ++ Q F+
Sbjct: 175 FTLIGLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFS 234
Query: 246 VGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHI 305
+G + L GLAY +WR LQ+ + P L Y+W +PES RWLL++ R EAI+++
Sbjct: 235 LGQMVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKA 294
Query: 306 AQKN-GKLPPADLKMLSLEEDVTEKLSPS--FADLFRTPRLRKRTFILMYLWFTDSVLYQ 362
A N KL P + L V EK PS DLFR P+LRK T I+ +WF DS+ Y
Sbjct: 295 ASVNRRKLSPELMNQL-----VPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYY 349
Query: 363 GLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIF 422
GL L +G ++YL L VE+P ++ + R GR + + +L G C+++IF
Sbjct: 350 GLSLQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIF 409
Query: 423 ISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
I DL + ++ VG+M A + + +AEL+PT + G
Sbjct: 410 IPADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTG 452
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 214 bits (546), Expect = 1e-55
Identities = 165/486 (33%), Positives = 240/486 (49%), Gaps = 26/486 (5%)
Query: 1 MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPIC---VGIVFLGFTPDHHCQSPGVAE 57
M D+++ +GE G FQ+ LI LLSA+ P + +VFL TP+H C+ P A
Sbjct: 1 MRDYDEVIAFLGEWGPFQR---LIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAAN 57
Query: 58 LSQRCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDW--NQSALSCVDPLASLATNRSH 115
LS W N +VP G C RY + N SAL ++P + +
Sbjct: 58 LSS--AWR-----NNSVPLRLRDGREVPHSCSRYRLATIANFSALG-LEPGRDV--DLGQ 107
Query: 116 LPLGPCQDGWVY--DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRF 173
L C DGW + D S++VTE+NLVC D+WK+ L S G L GS G +DRF
Sbjct: 108 LEQESCLDGWEFSQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRF 167
Query: 174 GRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSR 233
GRK L T+ V L FS ++ + ++ G+ N++ + L TE +G R
Sbjct: 168 GRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVR 227
Query: 234 RTVAIMYQMAF-TVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQ 292
+ + F VG + L AY + WR L LA+++P L + +W +PESPRWL+SQ
Sbjct: 228 IIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQ 287
Query: 293 KRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFA-DLFRTPRLRKRTFILM 351
+R EA I+ A+ N PA + S+EE K +F DLFRT + T + +
Sbjct: 288 RRFREAEDIIQKAAKMNNIAVPAVI-FDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSL 346
Query: 352 YLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNL 411
LW SV Y L L G+ YL+ SAL+EIP A + + + R Y +A
Sbjct: 347 LLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLF 406
Query: 412 LAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPACRGS 471
G L + + D ++L+I ++ +G+ GIT A M+ + AELYPT V + G
Sbjct: 407 WGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAV---GV 463
Query: 472 DATSSR 477
+T+SR
Sbjct: 464 TSTASR 469
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 211 bits (536), Expect = 2e-54
Identities = 164/523 (31%), Positives = 238/523 (45%), Gaps = 42/523 (8%)
Query: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG- 63
+D+L+QVG G FQ+ ++ L A F P HHC+ P A LS+ G
Sbjct: 4 NDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGL 63
Query: 64 --WSPAEELNYTVPGLGPAGEAFLGQCRRY-EVDWNQSALSCVDPLASLATNRSHLPLGP 120
W P + C R+ W L+ + + AT P
Sbjct: 64 EVWLPRDRQGQPE------------SCLRFTSPQWGLPFLNGTEANGTGATE-------P 104
Query: 121 CQDGWVYD--TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLC 178
C DGW+YD T S+IVTE++LVC+ L QS G L G++ GY ADR GR+
Sbjct: 105 CTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKV 164
Query: 179 LLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAI 238
L+ L AVSG AF+PN+ FRLL G+ G + TL E++ +R V
Sbjct: 165 LILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGT 224
Query: 239 MYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEA 298
+ +++G L G+AYA+PHWR LQL VS P F F +Y W ES RW S R
Sbjct: 225 LIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLT 284
Query: 299 IKIMDHIAQKNGKLPP-ADLKM----LSLEEDVT-EKLSPSFADLFRTPRLRKRTFILMY 352
++ + +A+ NGK A L M SL++++T K S +L R P LR L
Sbjct: 285 LRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSM 344
Query: 353 LWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLL 412
LWF S Y GL++ + ++YL + V++P + + I+ +GR + LL
Sbjct: 345 LWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLL 404
Query: 413 AGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG---PACR 469
AG L+ I D + + +G+ + + I L ELYPT + V P
Sbjct: 405 AGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRAVTVLLPETL 464
Query: 470 G-------SDATSSRDQGGRFARDHEGRREPWEKSKAQRKHDL 505
G D S + + R ++H+ P + S AQ K+ L
Sbjct: 465 GQPLPDTVQDLESRKGKQTRQQQEHQKYMVPLQAS-AQEKNGL 506
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 209 bits (533), Expect = 4e-54
Identities = 152/472 (32%), Positives = 219/472 (46%), Gaps = 31/472 (6%)
Query: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG- 63
+D+L+QVG G FQ+ ++ L A F P HHC+ P A LS+ G
Sbjct: 4 NDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGL 63
Query: 64 --WSPAEELNYTVPGLGPAGEAFLGQCRRY-EVDWNQSALSCVDPLASLATNRSHLPLGP 120
W P + C R+ W L+ + + AT P
Sbjct: 64 EVWLPRDRQGQPE------------SCLRFTSPQWGLPFLNGTEANGTGATE-------P 104
Query: 121 CQDGWVYD--TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLC 178
C DGW+YD T S+IVTE++LVC+ L QS G L G++ GY ADR GR+
Sbjct: 105 CTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKV 164
Query: 179 LLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAI 238
L+ L AVSG AF+PN+ FRLL G+ G + TL E++ +R V
Sbjct: 165 LILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGT 224
Query: 239 MYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEA 298
+ +++G L G+AYA+PHWR LQL VS P F F +Y W ES RW S R
Sbjct: 225 LIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLT 284
Query: 299 IKIMDHIAQKNGKLPP-ADLKM----LSLEEDVT-EKLSPSFADLFRTPRLRKRTFILMY 352
++ + +A+ NGK A L M SL++++T K S +L R P LR L
Sbjct: 285 LRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSM 344
Query: 353 LWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLL 412
LWF S Y GL++ + ++YL + V++P + + I+ +GR + LL
Sbjct: 345 LWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLL 404
Query: 413 AGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGV 464
AG L+ I D + + +G+ + + I L ELYPT + V
Sbjct: 405 AGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRAV 456
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 209 bits (533), Expect = 4e-54
Identities = 152/473 (32%), Positives = 219/473 (46%), Gaps = 31/473 (6%)
Query: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG- 63
+D+L+QVG G FQ+ ++ L A F P HHC+ P A LS+ G
Sbjct: 4 NDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGL 63
Query: 64 --WSPAEELNYTVPGLGPAGEAFLGQCRRY-EVDWNQSALSCVDPLASLATNRSHLPLGP 120
W P + C R+ W L+ + + AT P
Sbjct: 64 EVWLPRDRQGQPE------------SCLRFTSPQWGLPFLNGTEANGTGATE-------P 104
Query: 121 CQDGWVYD--TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLC 178
C DGW+YD T S+IVTE++LVC+ L QS G L G++ GY ADR GR+
Sbjct: 105 CTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKV 164
Query: 179 LLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAI 238
L+ L AVSG AF+PN+ FRLL G+ G + TL E++ +R V
Sbjct: 165 LILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGT 224
Query: 239 MYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEA 298
+ +++G L G+AYA+PHWR LQL VS P F F +Y W ES RW S R
Sbjct: 225 LIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLT 284
Query: 299 IKIMDHIAQKNGKLPP-ADLKM----LSLEEDVT-EKLSPSFADLFRTPRLRKRTFILMY 352
++ + +A+ NGK A L M SL++++T K S +L R P LR L
Sbjct: 285 LRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSM 344
Query: 353 LWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLL 412
LWF S Y GL++ + ++YL + V++P + + I+ +GR + LL
Sbjct: 345 LWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLL 404
Query: 413 AGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
AG L+ I D + + +G+ + + I L ELYPT + G
Sbjct: 405 AGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTG 457
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 209 bits (533), Expect = 4e-54
Identities = 152/473 (32%), Positives = 219/473 (46%), Gaps = 31/473 (6%)
Query: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG- 63
+D+L+QVG G FQ+ ++ L A F P HHC+ P A LS+ G
Sbjct: 4 NDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGL 63
Query: 64 --WSPAEELNYTVPGLGPAGEAFLGQCRRY-EVDWNQSALSCVDPLASLATNRSHLPLGP 120
W P + C R+ W L+ + + AT P
Sbjct: 64 EVWLPRDRQGQPE------------SCLRFTSPQWGLPFLNGTEANGTGATE-------P 104
Query: 121 CQDGWVYD--TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLC 178
C DGW+YD T S+IVTE++LVC+ L QS G L G++ GY ADR GR+
Sbjct: 105 CTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKV 164
Query: 179 LLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAI 238
L+ L AVSG AF+PN+ FRLL G+ G + TL E++ +R V
Sbjct: 165 LILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGT 224
Query: 239 MYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEA 298
+ +++G L G+AYA+PHWR LQL VS P F F +Y W ES RW S R
Sbjct: 225 LIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLT 284
Query: 299 IKIMDHIAQKNGKLPP-ADLKM----LSLEEDVT-EKLSPSFADLFRTPRLRKRTFILMY 352
++ + +A+ NGK A L M SL++++T K S +L R P LR L
Sbjct: 285 LRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSM 344
Query: 353 LWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLL 412
LWF S Y GL++ + ++YL + V++P + + I+ +GR + LL
Sbjct: 345 LWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLL 404
Query: 413 AGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
AG L+ I D + + +G+ + + I L ELYPT + G
Sbjct: 405 AGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTG 457
>gi|31542327 solute carrier family 22, member 16 [Homo sapiens]
Length = 577
Score = 201 bits (510), Expect = 2e-51
Identities = 149/478 (31%), Positives = 224/478 (46%), Gaps = 32/478 (6%)
Query: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAE---LSQR 61
+ I + VG G FQ+ + I + + + VF+G TP H C+ PG
Sbjct: 7 EGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNH 66
Query: 62 CGWS--------PAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNR 113
WS + + +Y L L +C R + + N S+L ++
Sbjct: 67 SNWSLEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRE-NTSSLG-----YEYTGSK 120
Query: 114 SHLPLGPCQDGWVYD--TPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFAD 171
PC DG++YD T S+ VT++NLVC W L Q G L GS+ GYF+D
Sbjct: 121 KEF---PCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSD 177
Query: 172 RFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSG 231
R GR++ L T + G+ AF+ +Y + + R +V+ G + G+ + EF+G
Sbjct: 178 RLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMK 237
Query: 232 SRRTVAIMYQMAFTVG--LVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWL 289
SR ++ F VG LVALTG Y + W Q+ +S T F+L W +PE+P WL
Sbjct: 238 SRTWASVHLHSFFAVGTLLVALTG--YLVRTWWLYQMILSTVTVPFILCCWVLPETPFWL 295
Query: 290 LSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLE------EDVTEKLSPSFADLFRTPRL 343
LS+ R EA KI+D +A+ N ++LSL+ TE + + LF +
Sbjct: 296 LSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSI 355
Query: 344 RKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRI 403
KRT + +WFT S+ + L+ GN YL+ +VEIP I +D+VGR
Sbjct: 356 TKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRR 415
Query: 404 YPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFV 461
+A S + AC V++ I + L ++ VG+ I A +I L AELYPT V
Sbjct: 416 TVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIV 473
>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
Length = 555
Score = 193 bits (491), Expect = 3e-49
Identities = 146/476 (30%), Positives = 219/476 (46%), Gaps = 37/476 (7%)
Query: 6 DILEQVGESGWFQKQAFLILCLLSAAFAPICVGIV--FLGFTPDHHCQSPG---VAELSQ 60
D+L+ +G G FQ +L L A C + F P HHC+ P A +
Sbjct: 5 DLLDALGSMGRFQLNHTALLLLPCGLLA--CHNFLQNFTAAVPPHHCRGPANHTEASTND 62
Query: 61 RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP 120
W L T+P L G CRR+ P +L + S +P
Sbjct: 63 SGAW-----LRATIP-LDQLGAP--EPCRRF-----------TKPQWALLSPNSSIPGAA 103
Query: 121 ---CQDGWVYDTP--GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGR 175
C+DGWVY+ S+IV E++LVC DL QS AG L G+ G ADR G
Sbjct: 104 TEGCKDGWVYNRSVFPSTIVMEWDLVCEARTLRDLAQSVYMAGVLVGAAVFGSLADRLGC 163
Query: 176 KLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRT 235
K L+ + L A SG A+ ++ + +FR L G+ G + +L+ E++ + R
Sbjct: 164 KGPLVWSYLQLAASGAATAYFSSFSAYCVFRFLMGMTFSGIILNSVSLVVEWMPTRGRTV 223
Query: 236 VAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRN 295
I+ +FT+G + L G+AY + WR LQ A+S P +F LY W +PES RWLL ++
Sbjct: 224 AGILLGYSFTLGQLILAGVAYLIRPWRCLQFAISAPFLIFFLYSWWLPESSRWLLLHGKS 283
Query: 296 TEAIKIMDHIAQKNG------KLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFI 349
A++ + +A NG +L + E + S S DLFRTP +RK T
Sbjct: 284 QLAVQNLQKVAAMNGRKEEGERLTKEVMSSYIQSEFASVCTSNSILDLFRTPAIRKVTCC 343
Query: 350 LMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMS 409
LM +WF++SV Y GL + + +LYL ++ P +A T+ VGR +A
Sbjct: 344 LMVIWFSNSVAYYGLAMDLQKFGLSLYLVQALFGIINTPAMLVATATMIYVGRRATVASF 403
Query: 410 NLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
+LAG + +F+ L +G+ + + + L ELYPT + +G
Sbjct: 404 LILAGLMVIANMFVPEGTQILCTAQAALGKGCLASSFICVYLFTGELYPTEIRQMG 459
>gi|24497485 urate anion exchanger 1 isoform a [Homo sapiens]
Length = 553
Score = 192 bits (489), Expect = 5e-49
Identities = 151/469 (32%), Positives = 215/469 (45%), Gaps = 26/469 (5%)
Query: 6 DILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFT---PDHHCQSP----GVAEL 58
++L+ VG G FQ L L + +C + F+ P H C +P A+
Sbjct: 5 ELLDLVGGLGRFQ---VLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQA 61
Query: 59 SQRCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPL 118
S SP L ++P P QCRR+ Q +DP A+ AT+ S
Sbjct: 62 SILGSLSPEALLAISIP---PGPNQRPHQCRRFR----QPQWQLLDPNAT-ATSWSEADT 113
Query: 119 GPCQDGWVYDTP--GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRK 176
PC DGWVYD S+IV ++NLVC + QS AG L G+ G +DRFGR+
Sbjct: 114 EPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRR 173
Query: 177 LCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTV 236
L L + L AV G AF+P + LFR L G M TL+ E+ + +R V
Sbjct: 174 LVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLV 233
Query: 237 AIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNT 296
+ + F+ G +AY + W LQL VS+P FL LY W + ES RWLL+ R
Sbjct: 234 MTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLD 293
Query: 297 EAIKIMDHIAQKNGK------LPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFIL 350
++ + +A NGK L P L EE + S L R P LR RT I
Sbjct: 294 WGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCIS 353
Query: 351 MYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSN 410
WF + GL L + A N++L ++ +V+IP AL+ + +GR +A S
Sbjct: 354 TLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASL 413
Query: 411 LLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPT 459
LLAG L + ++ L + +G G+ A I + ++EL+PT
Sbjct: 414 LLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPT 462
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 180 bits (457), Expect = 2e-45
Identities = 139/461 (30%), Positives = 215/461 (46%), Gaps = 16/461 (3%)
Query: 7 ILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ-RCGWS 65
+LEQ G G FQ L L + F P H C + + S +
Sbjct: 6 LLEQAGGVGLFQTLQVLTFILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGSAVSTNMT 65
Query: 66 PAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGW 125
P L ++P P QCRR+ Q +DP A+ AT+ S PC DGW
Sbjct: 66 PKALLTISIP---PGPNQGPHQCRRFR----QPQWQLLDPNAT-ATSWSEADTEPCVDGW 117
Query: 126 VYDTP--GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTV 183
VYD S+IV +++LVC+ L QS +G L GS G + RFGRK L
Sbjct: 118 VYDRSVFTSTIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCC 177
Query: 184 LVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMA 243
L AV+G F+P ++ R + G +++ TL+ E+ + R + A
Sbjct: 178 LQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCA 237
Query: 244 FTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMD 303
F+ G AL GLA+AL WR LQLA S+P F L W +PES RWL+ + + +A++ +
Sbjct: 238 FSAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELR 297
Query: 304 HIAQKNG----KLPPADLKMLSLEEDVTEKLSP-SFADLFRTPRLRKRTFILMYLWFTDS 358
+A+ NG K ++ M S++E+V P S DLF P LR R+ ++ + F+
Sbjct: 298 KVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLL 357
Query: 359 VLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACL 418
+ Y GL+ + + +++L V+ G + + +GR A S +AG A L
Sbjct: 358 ISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAIL 417
Query: 419 VMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPT 459
+ + DL L ++ +G+ I++ + + AEL+PT
Sbjct: 418 ANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPT 458
>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
sapiens]
Length = 546
Score = 180 bits (456), Expect = 3e-45
Identities = 138/477 (28%), Positives = 209/477 (43%), Gaps = 33/477 (6%)
Query: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGV-AELSQRCG 63
+++LEQVG G FQ + +L L + +FL P H C PG A S +
Sbjct: 4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDV 63
Query: 64 WSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD 123
W A L + L C R+ + + S PC
Sbjct: 64 WLEAH--------LPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQ 115
Query: 124 GWVYDTP--GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLG 181
GW YD S+I TE++LVC + AG L G++ GY +DRFGR+ LL
Sbjct: 116 GWEYDHSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLV 175
Query: 182 TVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLIT-----EFVGSGSRRTV 236
+ V G+ A S +Y+ + R L G +AG+T+I E++ R
Sbjct: 176 AYVSTLVLGLASAASVSYVMFAITRTLTGSA-----LAGFTIIVMPLELEWLDVEHRTVA 230
Query: 237 AIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNT 296
++ +T G++ L + Y + WRWL LAV+LP +L W VPES RWLL+Q
Sbjct: 231 GVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVK 290
Query: 297 EAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLS--------PSFADLFRTPRLRKRTF 348
EA + + H A+ NG+ D S ++ K++ PS+ DLFRTPRLR +
Sbjct: 291 EAHRYLLHCARLNGRPVCED----SFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISL 346
Query: 349 ILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAM 408
+ +WF + Y GL L + N+Y L VE+P + +++ GR A
Sbjct: 347 CCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAG 406
Query: 409 SNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
+ L A + +S D+ + ++ +G+ A L +ELYPT + G
Sbjct: 407 TLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTG 463
>gi|211059435 solute carrier family 22, member 24 [Homo sapiens]
Length = 551
Score = 176 bits (446), Expect = 4e-44
Identities = 138/489 (28%), Positives = 213/489 (43%), Gaps = 31/489 (6%)
Query: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSP----GVAELSQ 60
D +L+QVG G FQ C+ + P V F FTP H C P +
Sbjct: 4 DVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLENFTAFTPSHRCWVPLLDNDTVSDND 63
Query: 61 RCGWSPAEELNYTVP---GLGPAGEAFLGQCRRY-EVDWNQSALSCVDPLASLATNRSHL 116
S + L ++P L P +C+R+ W L+ P N +
Sbjct: 64 TGTLSKDDLLRISIPLDSNLRPQ------KCQRFIHPQWQLLHLNGTFP------NTNEP 111
Query: 117 PLGPCQDGWVYDTPG--SSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFG 174
PC DGWVYD S+IVTE++LVC + QS AG L G L G+ +DR G
Sbjct: 112 DTEPCVDGWVYDRSSFLSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVG 171
Query: 175 RKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRR 234
RK+ L A+S AF+P ++ + R L G + + L E+ SR
Sbjct: 172 RKIICKLCFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRS 231
Query: 235 TVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKR 294
++ +++VG + L GLA+A+ W LQL VS P + L W + ES RWL+ +
Sbjct: 232 MTIMVLLCSYSVGQMLLGGLAFAIQDWHILQLTVSTPIIVLFLSSWKMVESARWLIINNQ 291
Query: 295 NTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEK------LSPSFADLFRTPRLRKRTF 348
E +K + +A NGK + L +K + S LFR P+LR R F
Sbjct: 292 LDEGLKELRRVAHINGKKNTEETLTTELVRSTMKKELDAVRIKTSIFSLFRAPKLRMRVF 351
Query: 349 ILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAM 408
L ++ F +V + GLIL++ N+ L + V ++L+T++ +GR +
Sbjct: 352 GLCFVRFAITVPFYGLILNLQHLGSNVSLFQILCGAVTFTARCVSLLTLNHMGRRISQIL 411
Query: 409 SNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPAC 468
G LV F+ ++ L +++ +G ++ A + + EL PT +
Sbjct: 412 FTFPVGLFILVNTFLPQEMQILRVVLATLGIGSVSAASNSASVHHNELVPTILRS---TV 468
Query: 469 RGSDATSSR 477
G +A S R
Sbjct: 469 AGINAVSGR 477
>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
sapiens]
Length = 548
Score = 175 bits (443), Expect = 1e-43
Identities = 138/479 (28%), Positives = 209/479 (43%), Gaps = 35/479 (7%)
Query: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGV-AELSQRCG 63
+++LEQVG G FQ + +L L + +FL P H C PG A S +
Sbjct: 4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDV 63
Query: 64 WSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD 123
W A L + L C R+ + + S PC
Sbjct: 64 WLEAH--------LPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQ 115
Query: 124 GWVYDTP--GSSIVTE--FNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCL 179
GW YD S+I TE ++LVC + AG L G++ GY +DRFGR+ L
Sbjct: 116 GWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLL 175
Query: 180 LGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLIT-----EFVGSGSRR 234
L + V G+ A S +Y+ + R L G +AG+T+I E++ R
Sbjct: 176 LVAYVSTLVLGLASAASVSYVMFAITRTLTGSA-----LAGFTIIVMPLELEWLDVEHRT 230
Query: 235 TVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKR 294
++ +T G++ L + Y + WRWL LAV+LP +L W VPES RWLL+Q
Sbjct: 231 VAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGH 290
Query: 295 NTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLS--------PSFADLFRTPRLRKR 346
EA + + H A+ NG+ D S ++ K++ PS+ DLFRTPRLR
Sbjct: 291 VKEAHRYLLHCARLNGRPVCED----SFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHI 346
Query: 347 TFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPM 406
+ + +WF + Y GL L + N+Y L VE+P + +++ GR
Sbjct: 347 SLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQ 406
Query: 407 AMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
A + L A + +S D+ + ++ +G+ A L +ELYPT + G
Sbjct: 407 AGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTG 465
>gi|157426885 organic cation transporter like 4 [Homo sapiens]
Length = 594
Score = 174 bits (442), Expect = 1e-43
Identities = 133/478 (27%), Positives = 222/478 (46%), Gaps = 35/478 (7%)
Query: 6 DILEQVGESGWFQKQ--AFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCG 63
++L+ VGE G FQ++ A + + +AF VF P +C + + +
Sbjct: 54 NLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKP--YCNTSWILAVGPHL- 110
Query: 64 WSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD 123
S AE+LN T+P P G +FL V WN +D + N + CQD
Sbjct: 111 -SKAEQLNLTIPQ-APNG-SFLTCFMYLPVPWN------LDSIIQFGLNDTDT----CQD 157
Query: 124 GWVY-DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGT 182
GW+Y D S++ EF+LVC K D Q AG GSL D+ GR +L +
Sbjct: 158 GWIYPDAKKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLS 217
Query: 183 VLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQM 242
+L + G AF ++ L FR G ++ +L TE++ R I+
Sbjct: 218 LLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHC 277
Query: 243 AFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIM 302
F VG V LTG+AY+LPHW+ L L + F+ Y W +PESPRWL+ + + EA +++
Sbjct: 278 FFAVGAVLLTGIAYSLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVL 337
Query: 303 DHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQ 362
+ A N K P++L + L+ + S D + +L K T ++ +WFT S Y
Sbjct: 338 CYAASVNKKTIPSNL-LDELQLPRKKVTRASVLDFCKNRQLCKVTLVMSCVWFTVSYTYF 396
Query: 363 GLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIF 422
L L M +++ + +++E+P + + ++GR + +A++ L A CL+++F
Sbjct: 397 TLSLRMRELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLF 456
Query: 423 I---------------SPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
+ + +L + I+++ + + + + L AEL PT + G
Sbjct: 457 LPEGEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATG 514
>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
Length = 547
Score = 164 bits (414), Expect = 2e-40
Identities = 135/473 (28%), Positives = 216/473 (45%), Gaps = 52/473 (10%)
Query: 4 VDDILEQVGESGWFQKQ-AFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRC 62
V++ + VGE G +Q FL+ LL A + I +G TP +H
Sbjct: 3 VEEAFQAVGEMGIYQMYLCFLLAVLLQLYVATEAILIALVGATPSYH------------- 49
Query: 63 GWSPAEELNYTVPGLGPAGE--AFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP 120
W AE L G AGE AF DW L N S +
Sbjct: 50 -WDLAELLPNQSHGNQSAGEDQAF--------GDW------------LLTANGSEI---- 84
Query: 121 CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL 180
+ + +SI +E+ L+ S+K+ S +G G + G +DRFGRK L
Sbjct: 85 -HKHVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYL 143
Query: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY 240
++ + + FSP+Y + R L G+++ G + + L+ E VG+ +
Sbjct: 144 TGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG 203
Query: 241 QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK 300
+ F VG+ L Y + WR L + V+L + L +PESPRWL SQ R +EA +
Sbjct: 204 GLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEE 263
Query: 301 IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL 360
+ IA++N KL L+ + + + + SF DLFR L T ILM++WF S++
Sbjct: 264 ALYLIAKRNRKLKCT--FSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLV 321
Query: 361 YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDR--VGRIYPMAMSNLLAGAACL 418
Y GL L G G++Y + S L+EIP + + I++ GR ++ L G ACL
Sbjct: 322 YYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACL 381
Query: 419 VMIFI--SPDLHWLNII----IMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
+++F+ D ++ + +G++ I+ A ++ + +ELYPT + VG
Sbjct: 382 IVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVG 434
>gi|148664184 solute carrier family 22, member 10 [Homo sapiens]
Length = 541
Score = 159 bits (403), Expect = 4e-39
Identities = 110/367 (29%), Positives = 179/367 (48%), Gaps = 13/367 (3%)
Query: 120 PCQDGWVYDTP--GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKL 177
PC DGWVYD S+IVT+++LVC + Q L G L G + G+ +DRFGR+
Sbjct: 115 PCVDGWVYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRF 174
Query: 178 CLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVA 237
L +L A++ AF+P + + R L G S ITE++ S+ V
Sbjct: 175 ILRWCLLQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVV 234
Query: 238 IMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTE 297
I+ A ++G + L GLAY W+ L + S+P F+F L + ES RWL+ + E
Sbjct: 235 ILSSGALSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDE 294
Query: 298 AIKIMDHIAQKNG-KLPPADLKMLSLEEDVTEKL-----SPSFADLFRTPRLRKRTFILM 351
+K + +A+ NG K L + + + E+L + DLFR P +RKR IL+
Sbjct: 295 GLKALRKVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILV 354
Query: 352 YLWFTDSVLYQGLILHMGATSGNLY-LDFLYSALVEIPGAFIALITIDRVGRIYPMAMSN 410
+L F +++ + G ++++ N++ L LY A+ I +AL+T++ +GR +
Sbjct: 355 FLRFANTIPFYGTMVNLQHVGSNIFLLQVLYGAVALIVRC-LALLTLNHMGRRISQILFM 413
Query: 411 LLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVGPACRG 470
L G + L F+ ++ L + + C+G + + EL PT + G
Sbjct: 414 FLVGLSILANTFVPKEMQTLRVALACLGIGCSAATFSSVAVHFIELIPTVLRA---RASG 470
Query: 471 SDATSSR 477
D T+SR
Sbjct: 471 IDLTASR 477
>gi|153791484 putative UST1-like organic anion transporter [Homo
sapiens]
Length = 547
Score = 137 bits (345), Expect = 2e-32
Identities = 125/492 (25%), Positives = 202/492 (41%), Gaps = 44/492 (8%)
Query: 6 DILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCGWS 65
D+L+QVG G FQ + L + + F F DH C W
Sbjct: 5 DLLDQVGGLGRFQILQMVFLIMFNVIVYHQTQLENFAAFILDHRC-------------WV 51
Query: 66 PAEELNYTVPGLGP---AGEAFLG------------QCRRY-EVDWNQSALSCVDPLASL 109
+ N T+P P + +A L +CRR+ W L+ P
Sbjct: 52 HILD-NDTIPDNDPGTLSQDALLRISIPFDSNLRPEKCRRFVHPQWKLIHLNGTFP---- 106
Query: 110 ATNRSHLPLGPCQDGWVYDTPG--SSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVG 167
N S PC DGWVYD S+IVT+++LVC + + AG + G G
Sbjct: 107 --NTSEPDTEPCVDGWVYDQSSFPSTIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYG 164
Query: 168 YFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEF 227
+ +DRFGRK L + L A+ G AF+P + R L G + + LI E+
Sbjct: 165 HLSDRFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEW 224
Query: 228 VGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPR 287
+ + A ++G + L LA+ + LQL +S P F+F L+ + ES R
Sbjct: 225 ITHQFCAMALTLTLCAASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESAR 284
Query: 288 WLLSQKRNTEAIKIMDHIAQKNGKLPPAD-LKMLSLEEDVTEKLSP-----SFADLFRTP 341
WL+ + E +K + A +NG D L M L+ + ++L S +L R P
Sbjct: 285 WLIINNKPEEGLKELRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIP 344
Query: 342 RLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVG 401
+ KR L ++ F ++ + GL LH+ N++L V + +A ++ +
Sbjct: 345 NICKRICFLSFVRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPWALNHMS 404
Query: 402 RIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFV 461
R + L L +IF+ ++ L +++ +G ++ I EL P+ +
Sbjct: 405 RRLSQMLLMFLLATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSII 464
Query: 462 SGVGPACRGSDA 473
G G+ A
Sbjct: 465 RGRATGITGNFA 476
>gi|42542386 solute carrier family 22 (organic anion/cation
transporter), member 9 [Homo sapiens]
Length = 553
Score = 133 bits (334), Expect = 4e-31
Identities = 100/386 (25%), Positives = 169/386 (43%), Gaps = 18/386 (4%)
Query: 87 QCRRY-EVDWNQSALSCVDPLASLATNRSHLPLGPCQDGWVYD--TPGSSIVTEFNLVCA 143
+CRR+ W L+ P N S + PC DGWVYD + S+IVTE++LVC
Sbjct: 87 KCRRFVHPQWQLLHLNGTFP------NTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCD 140
Query: 144 DSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSML 203
+ + AG + G + G+ +DRFGR+ L L A+ G A +P ++
Sbjct: 141 SQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYC 200
Query: 204 LFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRW 263
R L G+ + LI E+ + + + + L GLA+A+ W
Sbjct: 201 SLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCPSGIAFMTLAGLAFAIRDWHI 260
Query: 264 LQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSL- 322
LQL VS+P F+ L + ES RWL+ + E +K + A ++G D L +
Sbjct: 261 LQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMKNARDTLTLEIL 320
Query: 323 ------EEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLY 376
E + +K PS ++ P + KR +L + F + + Y GL LH+ N++
Sbjct: 321 KSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHLGNNVF 380
Query: 377 -LDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIM 435
L L+ A++ + +A + + R + L L +IF+ ++ L ++
Sbjct: 381 LLQTLFGAVILLANC-VAPWALKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLA 439
Query: 436 CVGRMGITIAIQMICLVNAELYPTFV 461
+G +A + E+ PT +
Sbjct: 440 TLGLGASALANTLAFAHGNEVIPTII 465
>gi|24308167 SV2 related protein [Homo sapiens]
Length = 548
Score = 123 bits (309), Expect = 3e-28
Identities = 99/351 (28%), Positives = 163/351 (46%), Gaps = 39/351 (11%)
Query: 145 SWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLL 204
SW++ L S + G + S G +D++GRK L +VL G+L AF+P Y +L+
Sbjct: 119 SWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILV 178
Query: 205 FRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLA-YALPH--W 261
R L G G TL EF+ +R ++ ++ + +G V LA + +P W
Sbjct: 179 LRGLVGF-GIGGVPQSVTLYAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSLGW 237
Query: 262 RWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLS 321
RWL + ++P LF + + +PES R+ + +AI + IA +NG P ++S
Sbjct: 238 RWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIIS 297
Query: 322 LEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLIL------HMGATSG-- 373
+ED DLF TP R T +L ++WF+++ Y GL+L G G
Sbjct: 298 RQED-----RGKMRDLF-TPHFRWTTLLLWFIWFSNAFSYYGLVLLTTELFQAGDVCGIS 351
Query: 374 -------------------NLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAG 414
Y+D L++ L E PG + L IDR+GR MA+ ++
Sbjct: 352 SRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIF- 410
Query: 415 AACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
+ C +++FI + L +++ + R I+ Q + E+YPT +G
Sbjct: 411 SFCSLLLFICVGRNVLTLLLF-IARAFISGGFQAAYVYTPEVYPTATRALG 460
>gi|24497487 urate anion exchanger 1 isoform b [Homo sapiens]
Length = 332
Score = 110 bits (275), Expect = 3e-24
Identities = 75/240 (31%), Positives = 113/240 (47%), Gaps = 6/240 (2%)
Query: 226 EFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPES 285
E+ + +R V + + F+ G +AY + W LQL VS+P FL LY W + ES
Sbjct: 2 EWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAES 61
Query: 286 PRWLLSQKRNTEAIKIMDHIAQKNGK------LPPADLKMLSLEEDVTEKLSPSFADLFR 339
RWLL+ R ++ + +A NGK L P L EE + S L R
Sbjct: 62 ARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLR 121
Query: 340 TPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDR 399
P LR RT I WF + GL L + A N++L ++ +V+IP AL+ +
Sbjct: 122 MPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH 181
Query: 400 VGRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPT 459
+GR +A S LLAG L + ++ L + +G G+ A I + ++EL+PT
Sbjct: 182 LGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPT 241
>gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6
[Homo sapiens]
Length = 560
Score = 108 bits (271), Expect = 9e-24
Identities = 119/463 (25%), Positives = 192/463 (41%), Gaps = 45/463 (9%)
Query: 27 LLSAAFAP-ICVGIVF-----LGFTPDHHCQ-SPGVAELSQRCGWSPAEELNYTVPGLGP 79
L SA++ P I +G+V L P HC+ P + + R PA L+ +P LGP
Sbjct: 21 LASASWVPCIVLGLVLSSEELLTAQPAPHCRPDPTLLPPALRALRGPAL-LDAAIPRLGP 79
Query: 80 AGEAFLGQCRRYEVDWNQSALSCVDPLASLATNR-SHLPLGPCQDGWVYDTPGSSIVTEF 138
++A C+ PL L+ + + L P W G++ +
Sbjct: 80 T----------------RAASPCL-PLGVLSPSYLAPLTRAPRPSSWA-SCSGAAAGPTW 121
Query: 139 NLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPN 198
NLVC D WK+ L Q G+L G + +G DRFGR+ + ++++ G A + +
Sbjct: 122 NLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAAS 181
Query: 199 YMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYAL 258
+ ++L+ RLL G G +A Y E R ++ + VG + L GLA +
Sbjct: 182 FPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALV 241
Query: 259 PHWRWLQLAVSLPTFLFLLYYW---CVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLP-- 313
WR LQ +L + L LL++ PESP WLL+ + A KI+ A+ +G P
Sbjct: 242 QDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGD 301
Query: 314 ----------PADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQG 363
+L MLS SP L RT + IL + +
Sbjct: 302 SSLEENSLATATELTMLSARSPQPRYHSP--LGLLRTRVTWRNGLILGFSSLVGGGIRAS 359
Query: 364 LILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFI 423
+ YL + A +E L+T D GR + + ++ G A L+++
Sbjct: 360 FRRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAG 419
Query: 424 SPDL-HWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
+ L W + + +G + + L AE++PT + G G
Sbjct: 420 AQYLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAG 462
>gi|239745643 PREDICTED: hypothetical protein LOC146429 isoform 1
[Homo sapiens]
Length = 558
Score = 106 bits (264), Expect = 6e-23
Identities = 117/462 (25%), Positives = 186/462 (40%), Gaps = 45/462 (9%)
Query: 27 LLSAAFAP-ICVGIVF-----LGFTPDHHCQ-SPGVAELSQRCGWSPAEELNYTVPGLGP 79
L SA++ P I +G+V L P HC+ P + + R PA L+ +P LGP
Sbjct: 21 LASASWVPCIVLGLVLSSEELLTAQPAPHCRPDPTLLPPALRALRGPAL-LDAAIPRLGP 79
Query: 80 AGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGWVYDTPGSSIVTEFN 139
AL + P R+ P W G++ +N
Sbjct: 80 TRAP-------------AEALGVLSPSYLAPLTRAPRP-----SSWA-SCSGAAAGPTWN 120
Query: 140 LVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNY 199
LVC D WK+ L Q G+L G + +G DRFGR+ + ++++ G A + ++
Sbjct: 121 LVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAASF 180
Query: 200 MSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALP 259
++L+ RLL G G +A Y E R ++ + VG + L GLA +
Sbjct: 181 PTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALVQ 240
Query: 260 HWRWLQLAVSLPTFLFLLYYW---CVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLP--- 313
WR LQ +L + L LL++ PESP WLL+ + A KI+ A+ +G P
Sbjct: 241 DWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDS 300
Query: 314 ---------PADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGL 364
+L MLS SP L RT + IL + +
Sbjct: 301 SLEENSLATATELTMLSARSPQPRYHSP--LGLLRTRVTWRNGLILGFSSLVGGGIRASF 358
Query: 365 ILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFIS 424
+ YL + A +E L+T D GR + + ++ G A L+++ +
Sbjct: 359 RRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGLASLLLLAGA 418
Query: 425 PDL-HWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVSGVG 465
L W + + +G + + L AE++PT + G G
Sbjct: 419 QYLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAG 460
>gi|63999576 solute carrier family 22, member 17 isoform b [Homo
sapiens]
Length = 520
Score = 103 bits (257), Expect = 4e-22
Identities = 103/364 (28%), Positives = 161/364 (44%), Gaps = 24/364 (6%)
Query: 121 CQDGWVYDTPGSSIVT-----EFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGR 175
C W Y+ G ++T +++LVC W++ L Q GF G L +GY ADRFGR
Sbjct: 70 CLKDWDYN--GLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGR 127
Query: 176 KLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRT 235
+ +L T+ + GV A + + ++ R L G + G + Y + E R
Sbjct: 128 RGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLR 187
Query: 236 VAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYW--CVPESPRWLLSQK 293
VA+ ++ G GLA WR+LQ ++ P LFL Y W ES RWL+ ++
Sbjct: 188 VALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKR 247
Query: 294 RNTEAIKIMDHIAQKN-------GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKR 346
+ EA ++ +A++N G+ L+ L + S SFA L + K
Sbjct: 248 QIEEAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLNYRNIWKN 307
Query: 347 TFILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIAL----ITIDRVGR 402
L+ L FT+ + + + G DF +L+ A +A +T+DR GR
Sbjct: 308 ---LLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGR 364
Query: 403 IYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCV-GRMGITIAIQMICLVNAELYPTFV 461
+ +S L G A LV++ + L+ I V G A + L+ AE+ PT V
Sbjct: 365 RGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTV 424
Query: 462 SGVG 465
G G
Sbjct: 425 RGRG 428
>gi|170650643 solute carrier family 22, member 23 isoform a [Homo
sapiens]
Length = 686
Score = 99.0 bits (245), Expect = 9e-21
Identities = 73/298 (24%), Positives = 131/298 (43%), Gaps = 9/298 (3%)
Query: 133 SIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVL 192
++V++++LVC ++WK+ + + L G +FG L G AD GR+ LL +++ + G+
Sbjct: 214 NVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLT 273
Query: 193 MAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALT 252
+A S N R +G G + Y L E G R + ++ G +
Sbjct: 274 VALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMP 333
Query: 253 GLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKL 312
GLA W+ LQ + P L LLY+ PES RWL++ ++ A +++ H QKN
Sbjct: 334 GLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKNRMN 393
Query: 313 PPADLK--MLSLEEDVTEK-LSPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMG 369
P D+K + LE++++ + + T L K +L T ++ M
Sbjct: 394 PEGDIKGVIPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMM 453
Query: 370 ATS------GNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMI 421
N Y D+ +A + + + + +GR + + +L A L+ +
Sbjct: 454 GHEVKVPLLENFYADYYTTASIALVSCLAMCVVVRFLGRRGGLLLFMILTALASLLQL 511
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,484,109
Number of Sequences: 37866
Number of extensions: 872196
Number of successful extensions: 2587
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2378
Number of HSP's gapped (non-prelim): 108
length of query: 506
length of database: 18,247,518
effective HSP length: 107
effective length of query: 399
effective length of database: 14,195,856
effective search space: 5664146544
effective search space used: 5664146544
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.