Guide to the Human Genome
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Search of human proteins with 23503299

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23503299 proline rich 22 isoform 2 [Homo sapiens]
         (420 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23503299 proline rich 22 isoform 2 [Homo sapiens]                  885   0.0  
gi|197245373 proline rich 22 isoform 1 [Homo sapiens]                 759   0.0  
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     56   5e-08
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     56   5e-08
gi|11386183 WAS protein family, member 2 [Homo sapiens]                56   5e-08
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    56   5e-08
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                56   5e-08
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 55   9e-08
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      54   2e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    54   2e-07
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    54   2e-07
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           54   3e-07
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         54   3e-07
gi|153792074 proline rich 12 [Homo sapiens]                            53   5e-07
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]     52   8e-07
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              52   1e-06
gi|210032580 SET domain containing 1B [Homo sapiens]                   52   1e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  51   2e-06
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     51   2e-06
gi|194353976 transcription factor AP-2 epsilon (activating enhan...    51   2e-06
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]            51   2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   2e-06
gi|55750053 atrophin-1 [Homo sapiens]                                  51   2e-06
gi|55750041 atrophin-1 [Homo sapiens]                                  51   2e-06
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         50   3e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    50   3e-06
gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]          50   3e-06
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          50   4e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          50   4e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          50   4e-06

>gi|23503299 proline rich 22 isoform 2 [Homo sapiens]
          Length = 420

 Score =  885 bits (2287), Expect = 0.0
 Identities = 420/420 (100%), Positives = 420/420 (100%)

Query: 1   MSPKDKLCVIHHPARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLP 60
           MSPKDKLCVIHHPARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLP
Sbjct: 1   MSPKDKLCVIHHPARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLP 60

Query: 61  PTGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYL 120
           PTGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYL
Sbjct: 61  PTGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYL 120

Query: 121 KAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAP 180
           KAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAP
Sbjct: 121 KAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAP 180

Query: 181 LPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPG 240
           LPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPG
Sbjct: 181 LPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPG 240

Query: 241 VPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEP 300
           VPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEP
Sbjct: 241 VPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEP 300

Query: 301 EGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALD 360
           EGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALD
Sbjct: 301 EGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALD 360

Query: 361 EEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATPH 420
           EEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATPH
Sbjct: 361 EEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATPH 420


>gi|197245373 proline rich 22 isoform 1 [Homo sapiens]
          Length = 422

 Score =  759 bits (1959), Expect = 0.0
 Identities = 360/361 (99%), Positives = 360/361 (99%)

Query: 60  PPTGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 119
           PP GFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY
Sbjct: 62  PPAGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY 121

Query: 120 LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA 179
           LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA
Sbjct: 122 LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPA 181

Query: 180 PLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARP 239
           PLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARP
Sbjct: 182 PLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARP 241

Query: 240 GVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASE 299
           GVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASE
Sbjct: 242 GVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASE 301

Query: 300 PEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKAL 359
           PEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKAL
Sbjct: 302 PEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKAL 361

Query: 360 DEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 419
           DEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP
Sbjct: 362 DEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 421

Query: 420 H 420
           H
Sbjct: 422 H 422


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 54/172 (31%), Positives = 61/172 (35%), Gaps = 32/172 (18%)

Query: 95  LAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYP------HYQQAPGGPQFLLP----- 143
           L   SG     P APG     P P    P  PP P           PGG     P     
Sbjct: 579 LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG 638

Query: 144 --YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP----KENKPPPVLIT 197
               PP  P PE +G    +       +P PP   G A +PPPPP        PPP    
Sbjct: 639 DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP-PP 697

Query: 198 LPAEPTLPPDAYSHLQGHLGHFPG-PEPLAFPVKELQGSGARPGVPLYPPGL 248
           LP E  +PP       G     PG P P  FP          PG+P  PPG+
Sbjct: 698 LPGEAGMPPPPPPLPGG-----PGIPPPPPFP--------GGPGIPPPPPGM 736



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 56/202 (27%), Positives = 68/202 (33%), Gaps = 65/202 (32%)

Query: 7   LCVIHHPARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLG-PSGSSCSQGTRLPPTGFQ 65
           +C+   P+      +  PP  P +G   +  P   P  G+G PS SS   GT +PP    
Sbjct: 616 VCISSPPSLPGGTAISPPP--PLSGDATIPPPPPLPE-GVGIPSPSSLPGGTAIPPP--- 669

Query: 66  MAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGL 125
                              P L  SA          P   P  PGS  + P P       
Sbjct: 670 -------------------PPLPGSARI--------PPPPPPLPGSAGIPPPP------- 695

Query: 126 PPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP 185
           PP P     P  P  L     P GPG                 +P PP   G   +PPPP
Sbjct: 696 PPLPGEAGMPPPPPPL-----PGGPG-----------------IPPPPPFPGGPGIPPPP 733

Query: 186 PKEN--KPPPVLITLPAEPTLP 205
           P      PPP    +PA P LP
Sbjct: 734 PGMGMPPPPPFGFGVPAAPVLP 755



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 14/93 (15%)

Query: 169 LPLPPLEEGPAPLPPPPPKENK-----PPPVL---ITLPAEPTLPPDAYSHLQGHL---- 216
           + +PP     AP+PP PP         PPP      T P  P  PP     L G +    
Sbjct: 561 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISS 620

Query: 217 -GHFPGPEPLAFPVKELQGSGARPGVPLYPPGL 248
               PG   ++ P   L G    P  P  P G+
Sbjct: 621 PPSLPGGTAIS-PPPPLSGDATIPPPPPLPEGV 652


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 54/172 (31%), Positives = 61/172 (35%), Gaps = 32/172 (18%)

Query: 95  LAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYP------HYQQAPGGPQFLLP----- 143
           L   SG     P APG     P P    P  PP P           PGG     P     
Sbjct: 588 LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG 647

Query: 144 --YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP----KENKPPPVLIT 197
               PP  P PE +G    +       +P PP   G A +PPPPP        PPP    
Sbjct: 648 DATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP-PP 706

Query: 198 LPAEPTLPPDAYSHLQGHLGHFPG-PEPLAFPVKELQGSGARPGVPLYPPGL 248
           LP E  +PP       G     PG P P  FP          PG+P  PPG+
Sbjct: 707 LPGEAGMPPPPPPLPGG-----PGIPPPPPFP--------GGPGIPPPPPGM 745



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 56/202 (27%), Positives = 68/202 (33%), Gaps = 65/202 (32%)

Query: 7   LCVIHHPARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLG-PSGSSCSQGTRLPPTGFQ 65
           +C+   P+      +  PP  P +G   +  P   P  G+G PS SS   GT +PP    
Sbjct: 625 VCISSPPSLPGGTAISPPP--PLSGDATIPPPPPLPE-GVGIPSPSSLPGGTAIPPP--- 678

Query: 66  MAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGL 125
                              P L  SA          P   P  PGS  + P P       
Sbjct: 679 -------------------PPLPGSARI--------PPPPPPLPGSAGIPPPP------- 704

Query: 126 PPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP 185
           PP P     P  P  L     P GPG                 +P PP   G   +PPPP
Sbjct: 705 PPLPGEAGMPPPPPPL-----PGGPG-----------------IPPPPPFPGGPGIPPPP 742

Query: 186 PKEN--KPPPVLITLPAEPTLP 205
           P      PPP    +PA P LP
Sbjct: 743 PGMGMPPPPPFGFGVPAAPVLP 764



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 14/93 (15%)

Query: 169 LPLPPLEEGPAPLPPPPPKENK-----PPPVL---ITLPAEPTLPPDAYSHLQGHL---- 216
           + +PP     AP+PP PP         PPP      T P  P  PP     L G +    
Sbjct: 570 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISS 629

Query: 217 -GHFPGPEPLAFPVKELQGSGARPGVPLYPPGL 248
               PG   ++ P   L G    P  P  P G+
Sbjct: 630 PPSLPGGTAIS-PPPPLSGDATIPPPPPLPEGV 661


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 37/111 (33%), Positives = 43/111 (38%), Gaps = 18/111 (16%)

Query: 102 PAGVPSAPGSYLLEPQPY---LKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFV 158
           PA  P  P    + P P      +PG PP P     P  P F  P  PP  P        
Sbjct: 320 PAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA------- 372

Query: 159 GDAGPAAFVELPLPPLEE---GPAPLPPPPPKENKPPPVLITLPAEPTLPP 206
                A +  LP PPL +   G  P PPPPP    PPP       +P +PP
Sbjct: 373 -----ADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPP 418



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 43/152 (28%), Positives = 50/152 (32%), Gaps = 28/152 (18%)

Query: 116 PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG---PEALGFVGDAGPAAFVELPLP 172
           P P      LPP P         +F  P     G G   P+    V  + P     L  P
Sbjct: 258 PSPSFSEDNLPPPP--------AEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSP 309

Query: 173 P-----LEEGPAPLPPPPPK---ENKPPPVLITLPAEPTLP-PDAYSHLQGHLGHFPGPE 223
           P         PAP PPPPP       PPPV    P  P  P P ++          P P 
Sbjct: 310 PGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPP 369

Query: 224 PLAF--------PVKELQGSGARPGVPLYPPG 247
           P A         P+ +  G    P  P  PPG
Sbjct: 370 PPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG 401



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 45/164 (27%), Positives = 50/164 (30%), Gaps = 49/164 (29%)

Query: 17  PKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPR 76
           PK     PP  PP    ++  P   P +G G      S GT  PP+     P        
Sbjct: 312 PKPGFAPPPAPPPPPPPMIGIPPPPPPVGFG------SPGTPPPPSPPSFPP-------- 357

Query: 77  IYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPG 136
                   PD                A  P  P      P P    P LPP P  Q   G
Sbjct: 358 -------HPDF---------------AAPPPPP------PPPAADYPTLPPPPLSQPTGG 389

Query: 137 GPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAP 180
            P    P  PP  PGP    F G  G  A      PPL +   P
Sbjct: 390 APP---PPPPPPPPGPPPPPFTGADGQPAIP----PPLSDTTKP 426



 Score = 28.9 bits (63), Expect = 9.1
 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 13/92 (14%)

Query: 331 EELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGP---PATNTPAPILSGKRKAST 387
           E + +  Y  P   D+ S+    F+    ++  PP P     P  N     L+G +++S 
Sbjct: 239 ENVDASSYPPPPQSDSASSPSPSFS----EDNLPPPPAEFSYPVDNQRGSGLAGPKRSSV 294

Query: 388 AKKGKPGRKARQPAGPASATPPGPREDLGATP 419
                P      P  P   +PPGP+      P
Sbjct: 295 VSPSHP------PPAPPLGSPPGPKPGFAPPP 320


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 48/140 (34%), Positives = 58/140 (41%), Gaps = 21/140 (15%)

Query: 86  DLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPY--LKAPGLPPYPHYQQAPGGPQFLLP 143
           D   S    L A   G  G+P+ P  +L  P P   L  P LPP P        P F+ P
Sbjct: 527 DTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPP--------PDFMEP 578

Query: 144 YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPT 203
             PP+   P    + G AG     ELP PP    PAP P P P   +PPP    +   P 
Sbjct: 579 --PPDFVPPPPPSYAGIAGS----ELPPPP-PPPPAPAPAPVPDSARPPP---AVAKRPP 628

Query: 204 LPPDAYSHLQGHLGHFPGPE 223
           +PP    +  GH G   G E
Sbjct: 629 VPPKRQEN-PGHPGGAGGGE 647



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 39/132 (29%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 129 PHYQQAPGGPQFLLPYFPP-------EGPGPEALGFVGDAG------PAAFVELPLPPLE 175
           P   +AP  P+  LP  PP        G     L   G  G      P  F+  P PP  
Sbjct: 503 PAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPP 562

Query: 176 EGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG-HLGHFPGPEPLAFPVKELQG 234
                LPPPPP   +PPP  +        PP +Y+ + G  L   P P P   P      
Sbjct: 563 LDDPELPPPPPDFMEPPPDFV------PPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDS 616

Query: 235 SGARPGVPLYPP 246
           +   P V   PP
Sbjct: 617 ARPPPAVAKRPP 628



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 17/47 (36%), Positives = 18/47 (38%), Gaps = 2/47 (4%)

Query: 362 EQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQ--PAGPASA 406
           E PP P PP    PAP+    R      K  P    RQ  P  P  A
Sbjct: 597 ELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGA 643


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 94/311 (30%), Positives = 108/311 (34%), Gaps = 64/311 (20%)

Query: 25  PKGPPNGKVLVASPKQAPRLG-LGPSGSSCSQGTRLP-----PTGFQMAPCGCFFDPRIY 78
           PKGPP G   V  P  A   G  GPSG+    GTR P     PTG+ M            
Sbjct: 271 PKGPP-GVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMP----------- 318

Query: 79  RIEWTTPDLGQSALYKLAASSGGPA--GVPSAPGSYLLEPQPYLKA----PGL--PPYPH 130
            +     D G + +  L    G P   G P   G   L   P L      PG   PP P 
Sbjct: 319 GLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPK 378

Query: 131 YQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEG-PAPLPPPPPKEN 189
            +  PGGP             P   G  GD GP+     P  P E G P    PP P   
Sbjct: 379 GEAGPGGP-------------PGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGP 425

Query: 190 KPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFP--VKELQGSGARPGVPLYPPG 247
           K  P     P  P +        +G LG  PG   L  P  +  LQG    P  P+ P G
Sbjct: 426 KGEPGFTGRPGGPGVA--GALGQKGDLG-LPGQPGLRGPSGIPGLQG----PAGPIGPQG 478

Query: 248 LSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEV 307
           L  LK      G   G G+A  P TA     P               PG + P G     
Sbjct: 479 LPGLKGEPGLPGP-PGEGRAGEPGTAGPTGPPG----------VPGSPGITGPPGP---- 523

Query: 308 PGPALPDSSGG 318
           PGP  P  + G
Sbjct: 524 PGPPGPPGAPG 534



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 94/357 (26%), Positives = 113/357 (31%), Gaps = 101/357 (28%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGP-GPEALGFVG 159
           GP G P  PG      +P +  PGL    H Q  P GP    P F   G  GP   G  G
Sbjct: 86  GPRGPPGPPG---FPGKPGMGKPGL----HGQPGPAGP----PGFSRMGKAGPP--GLPG 132

Query: 160 DAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLP----PDAYSHLQGH 215
             GP     L   P   G   L  PP     P P  IT+P +P       P  +    G 
Sbjct: 133 KVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGP 192

Query: 216 LGHFPGP---------EPLAFP-VKELQGSGARPGVPLYP-------PGLSELKVAEVKE 258
            G  PGP           +  P +    G G  PG P  P       PGL  L  A   +
Sbjct: 193 QGE-PGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDK 251

Query: 259 GALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTL----CEVPGPA-LP 313
           G   G      P+                       PGA  P+G        VPG A LP
Sbjct: 252 GE-SGPPGVPGPRGE---------------------PGAVGPKGPPGVDGVGVPGAAGLP 289

Query: 314 DSSGGNSADDIRSLCLPEELLS-FDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPAT 372
              G + A        P  L+    Y +P +                       PGP   
Sbjct: 290 GPQGPSGAKGEPGTRGPPGLIGPTGYGMPGL-----------------------PGPKGD 326

Query: 373 NTPA--PILSGKRKASTAKKGKPGRKARQPAG-----------PASATPPGPREDLG 416
             PA  P L G R     + G+PG +  Q  G           P    PPGP+ + G
Sbjct: 327 RGPAGVPGLLGDR-GEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG 382



 Score = 33.1 bits (74), Expect = 0.48
 Identities = 44/162 (27%), Positives = 55/162 (33%), Gaps = 50/162 (30%)

Query: 97  ASSGGPAGVPS--APGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEA 154
           ASSGG AG  +  AP  Y+   QP  K P  PP+                          
Sbjct: 26  ASSGGGAGGAAGYAPVKYI---QPMQKGPVGPPFRE------------------------ 58

Query: 155 LGFVGDAGPAAFVELPLP--PLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHL 212
                  G   ++E+PLP  P++    P PP  P    PP      P  P  P      L
Sbjct: 59  -------GKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGP----PGFPGKPGMGKPGL 107

Query: 213 QGHLGHFPGPEPLAFPVKELQGSGARPGVP--LYPPGLSELK 252
            G       P P   P     G    PG+P  + PPG   L+
Sbjct: 108 HGQ------PGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLR 143



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 34/104 (32%), Positives = 40/104 (38%), Gaps = 20/104 (19%)

Query: 87  LGQSALYKLAASSG--GPAGVPSAPG-SYLLEPQ--PYLKA-PGLPPYPHYQQA------ 134
           LGQ     L    G  GP+G+P   G +  + PQ  P LK  PGLP  P   +A      
Sbjct: 444 LGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTA 503

Query: 135 --------PGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELP 170
                   PG P    P  PP  PGP       D    A + LP
Sbjct: 504 GPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLP 547


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 57/174 (32%), Positives = 67/174 (38%), Gaps = 13/174 (7%)

Query: 97  ASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGP--EA 154
           ASS   A   S P S +  P P    P L P P     P GP   LP  PP G  P    
Sbjct: 386 ASSQQQAPPQSVPPSQIQAP-PMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRP 444

Query: 155 LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP-----KENKPPPVLITLPAEPTLPPDAY 209
            G  G  GP   +  P PP    P P P PPP        + PP  +  PA P +PP   
Sbjct: 445 PGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP 504

Query: 210 SHLQGHLGHFPGPEPLA-FPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALL 262
             ++  L    GP P   FP   L      PGV   PP L +   A+    A +
Sbjct: 505 GMMRPPLVPPLGPAPPGLFPPAPL----PNPGVLSAPPNLIQRPKADDTSAATI 554



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 18/49 (36%), Positives = 18/49 (36%), Gaps = 1/49 (2%)

Query: 364 PPHPGPPATNTPA-PILSGKRKASTAKKGKPGRKARQPAGPASATPPGP 411
           PP   PP    P  P L G           PGR    P GP    PPGP
Sbjct: 434 PPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGP 482


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 99/412 (24%), Positives = 127/412 (30%), Gaps = 122/412 (29%)

Query: 9   VIHHPARAPKQYLCRPPKGP-PNGKVLVASPKQAPRLGLGPS--GSSCSQGTRLPPTGFQ 65
           V   P  AP     RPP G  P G      P   P     P   G   S G+  PP   +
Sbjct: 87  VCPQPPTAPT----RPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICE 142

Query: 66  MAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGL 125
             P G    P+ Y  ++ + D+         A   GPAG P  PG     P      PG 
Sbjct: 143 SCPTG----PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPG-----PPGTSGHPGS 193

Query: 126 PPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP 185
           P  P YQ  PG P    P  PP  PG      +G +GPA          ++G +  P  P
Sbjct: 194 PGSPGYQGPPGEPGQAGPSGPPGPPGA-----IGPSGPAG---------KDGESGRPGRP 239

Query: 186 PKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYP 245
            +   P P                          PG          ++G    PG     
Sbjct: 240 GERGLPGP--------------------------PG----------IKGPAGIPGF---- 259

Query: 246 PGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLC 305
           PG+   +  + + G     G+  AP       LP +          +  PG   P G   
Sbjct: 260 PGMKGHRGFDGRNGE---KGETGAPGLKGENGLPGE----------NGAPGPMGPRGAPG 306

Query: 306 EVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPP 365
           E   P LP ++G    D  R                                   + QP 
Sbjct: 307 ERGRPGLPGAAGARGNDGARG---------------------------------SDGQPG 333

Query: 366 HPGPPAT----NTPAPILSGKRKASTAKKGKPGRKARQ-PAGPASAT-PPGP 411
            PGPP T     +P          S    G PG++    P G A A  PPGP
Sbjct: 334 PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP 385



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 113/421 (26%), Positives = 127/421 (30%), Gaps = 116/421 (27%)

Query: 25   PKGPPNGKVLVASPKQAPRLGL----GPSGSSCSQGTRLPP--TGFQMAPCGCFFDPRIY 78
            P GPP          +    GL    GP GS   +G   PP   GF  AP G   +P   
Sbjct: 766  PIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAP-GQNGEPGGK 824

Query: 79   RIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGP 138
                   + G+          GGP GV   PG            P  PP P   +   G 
Sbjct: 825  GERGAPGEKGE----------GGPPGVAGPPGG---------SGPAGPPGPQGVKGERGS 865

Query: 139  QFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPP---PPKENKPPPVL 195
                    P GPG  A GF G  G      LP PP   G    P P   P K+  P P  
Sbjct: 866  --------PGGPG--AAGFPGARG------LPGPPGSNGNPGPPGPSGSPGKDGPPGPAG 909

Query: 196  IT-LPAEPTLP-PDAYSHLQGHLGHFPG-------PEPLAFP----VKELQGSGARPGVP 242
             T  P  P +  P   +   G  G  PG       P PL        + L G    PG P
Sbjct: 910  NTGAPGSPGVSGPKGDAGQPGEKGS-PGAQGPPGAPGPLGIAGITGARGLAGPPGMPG-P 967

Query: 243  LYPPGLSELKVAEVKEGA--LLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEP 300
               PG   +K    K GA  L G      P+    LA        D     D LPG    
Sbjct: 968  RGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS 1027

Query: 301  EGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALD 360
             G   +      P + G                                           
Sbjct: 1028 PGGKGDRGENGSPGAPGA------------------------------------------ 1045

Query: 361  EEQPPHPGPPATNTPAPILSGKRKAS--TAKKGKPGRKARQPAGPASAT-PPGPREDLGA 417
               P HPGPP    PA   SG R  S      G PG     PAG   A  P GPR D G 
Sbjct: 1046 ---PGHPGPPGPVGPAG-KSGDRGESGPAGPAGAPG-----PAGSRGAPGPQGPRGDKGE 1096

Query: 418  T 418
            T
Sbjct: 1097 T 1097



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 88/337 (26%), Positives = 102/337 (30%), Gaps = 63/337 (18%)

Query: 25  PKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEWTT 84
           P+GPP GK     P+  P    GP+G    +G   PP      P G    P         
Sbjct: 604 PQGPP-GKNGETGPQGPP----GPTGPGGDKGDTGPP-----GPQGLQGLPGTGGPPGEN 653

Query: 85  PDLGQSALYKLAASSGGP-----AGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQ 139
              G+      A + G P     AG P   G   L   P L+    PP P   +   GP 
Sbjct: 654 GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP 713

Query: 140 FLLPYFPPEGPG-------PEALGFVGDAGPAAFVELPLPPLEEG-PAPLPPPPPKENKP 191
                 PP   G       P   G +G  GP      P  P  +G P    P  P     
Sbjct: 714 -----GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 192 PPVLITLPAE------PTLPPDAYSH-LQGHLGHFPGPEPLAFPVKELQ----------- 233
           PP     P +      P LP  A      G  G    P P  FP    Q           
Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828

Query: 234 -----GSGARPGV--------PLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPD 280
                G G  PGV        P  PPG   +K    + G+  G G A  P  AR L  P 
Sbjct: 829 APGEKGEGGPPGVAGPPGGSGPAGPPGPQGVK---GERGSPGGPGAAGFP-GARGLPGPP 884

Query: 281 KVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSG 317
                         PG   P G       P  P  SG
Sbjct: 885 GSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSG 921



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 101 GPAGVPSAPGSYLLE----PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALG 156
           GPAG P + G+        PQ +  A G P  P    +PGG   + P   P  PG   +G
Sbjct: 354 GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG--LMG 411

Query: 157 FVGDAGPA 164
             G  GPA
Sbjct: 412 ARGPPGPA 419



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 39/149 (26%), Positives = 47/149 (31%), Gaps = 18/149 (12%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKAP-GLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVG 159
           GP G+P   G       P    P G    P     PGGP        P GPG +      
Sbjct: 495 GPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK---- 550

Query: 160 DAGPAAFVELPLPPLEEGPAPLP-PPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGH 218
                     P PP  +G +  P PP P   +  P ++  P       D      G  G 
Sbjct: 551 ----------PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPK--GNDGAPGKNGERGG 598

Query: 219 FPGPEPLAFPVKELQGSGARPGVPLYPPG 247
             GP P   P K  +     P  P  P G
Sbjct: 599 PGGPGPQGPPGKNGETGPQGPPGPTGPGG 627



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 67/250 (26%), Positives = 83/250 (33%), Gaps = 48/250 (19%)

Query: 101  GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEG-PG-PEALGFV 158
            GPAG   APG     P     APG P  P   +   G +         G PG P A G  
Sbjct: 1068 GPAGPAGAPG-----PAGSRGAPG-PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP 1121

Query: 159  GDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGH 218
            G AG    +  P P    GP     PP K+                         GH G 
Sbjct: 1122 GPAGQQGAIGSPGPAGPRGPVGPSGPPGKDG----------------------TSGHPGP 1159

Query: 219  FPGPEPLA-FPVKELQGSGARPGV--PLYPPGLSELKVAEVKEGALLGAGKAKAPKTARA 275
               P P      +  +GS   PG   P  PPG        V   A+ G G  KA   A  
Sbjct: 1160 IGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPY 1219

Query: 276  LA---LPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSL--CLP 330
                 +  K+  ++ M     + G         ++     PD S  N A + R L  C P
Sbjct: 1220 YGDEPMDFKINTDEIMTSLKSVNG---------QIESLISPDGSRKNPARNCRDLKFCHP 1270

Query: 331  EELLSFDYSV 340
             EL S +Y V
Sbjct: 1271 -ELKSGEYWV 1279


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 74/257 (28%), Positives = 86/257 (33%), Gaps = 63/257 (24%)

Query: 95  LAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYP---------------HYQQAPG--- 136
           LAA +G   G    PG     P P    PG P  P               H+  AP    
Sbjct: 166 LAARAGPGPGPGPGPG-----PGP---GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL 217

Query: 137 ---GPQFLLPYFPPEGPGP--EALGFVGDAGPAAFVELPLPPLE---EGPAPLPPPPPKE 188
              GP  LLP   P  PG   +   FVG A P A    P PP       PA  PPPPP  
Sbjct: 218 VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA-PAAPSPPAAPAPAAPAAAPPPPP-- 274

Query: 189 NKPPPVLITLP---------AEPTLPPDAYSHLQGHLGHFPGPEPLA---FPVKELQGSG 236
             P P  +  P         A P +PP A +   G  G  P P P A     V    G G
Sbjct: 275 --PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPG 332

Query: 237 ARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPG 296
           A    P   PG+       V +          AP  A+ LA         +M +   + G
Sbjct: 333 AAAAAP--APGVKAESPKRVVQA---------APPAAQTLAASGPASTAASMVIGPTMQG 381

Query: 297 ASEPEGTLCEVPGPALP 313
           A  P       P P  P
Sbjct: 382 AL-PSPAAVPPPAPGTP 397



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 44/139 (31%), Positives = 48/139 (34%), Gaps = 34/139 (24%)

Query: 96  AASSGGPAGVPSAPGSYLLEPQPYLKA---------PGLPPYPHYQQAPGGPQ----FLL 142
           AA +G  A    APG+   EP P  +A         PG PP P     P GP      L 
Sbjct: 70  AAGAGPAAPAEGAPGA-APEPPPAGRARPGGGGPQRPG-PPSPRRPLVPAGPAPPAAKLR 127

Query: 143 PYFPPEG-----------------PGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP 185
           P  PPEG                 P P   G    AGPAA      P    GP P P P 
Sbjct: 128 P--PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185

Query: 186 PKENKPPPVLITLPAEPTL 204
           P +   P    TL     L
Sbjct: 186 PGKPAGPGAAQTLNGSAAL 204



 Score = 33.1 bits (74), Expect = 0.48
 Identities = 63/253 (24%), Positives = 77/253 (30%), Gaps = 42/253 (16%)

Query: 83  TTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLL 142
           T P +G +A    AA S   A  P+AP +    P P       PP       P GP    
Sbjct: 240 TPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP-----GHPAGPPTAA 294

Query: 143 PYFPP-------------EGPGPEA---LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP 186
           P  PP               P P A    G  G  GP A    P P ++        P  
Sbjct: 295 PAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK-----AESPKR 349

Query: 187 KENKPPPVLITL----PAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVP 242
                PP   TL    PA           +QG L     P P A P       G   G+P
Sbjct: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL-----PSPAAVPP---PAPGTPTGLP 401

Query: 243 LYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPG---ASE 299
               G     ++        G  +A    T  A  LP        ++ F   PG      
Sbjct: 402 KGAAGAVTQSLSRTPTATTSGI-RATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRS 460

Query: 300 PEGTLCEVPGPAL 312
             G L  +P  AL
Sbjct: 461 ENGQLLMIPQQAL 473



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 59/236 (25%), Positives = 76/236 (32%), Gaps = 31/236 (13%)

Query: 177 GPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSG 236
           G A   P  P E  P        A P  PP   +   G     PGP     P+  +    
Sbjct: 69  GAAGAGPAAPAEGAPG-------AAPEPPPAGRARPGGGGPQRPGPPSPRRPL--VPAGP 119

Query: 237 ARPGVPLYPPGLSEL-KVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLP 295
           A P   L PP        A V   A + AG   AP      A P  +            P
Sbjct: 120 APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG-----P 174

Query: 296 GASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFN 355
           G     G     PGP     +G  +A  +        LL+  ++    +  V+N      
Sbjct: 175 GPGPGPG-----PGPGPGKPAGPGAAQTLNGSAA---LLNSHHAAAPAVSLVNNGPAAL- 225

Query: 356 FKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGP 411
              L   +P  PG     TP P +      + A    P   A  PA PA+A PP P
Sbjct: 226 ---LPLPKPAAPGT-VIQTP-PFVGAAAPPAPAAPSPPAAPA--PAAPAAAPPPPP 274


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 67/226 (29%), Positives = 76/226 (33%), Gaps = 34/226 (15%)

Query: 25  PKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEWTT 84
           P   P+G    A+P   P  G  P+G   S    +PPTG    P   F            
Sbjct: 46  PSSVPSGLPPSATPSTVP-FGPAPTGMYPS----VPPTGPPPGPPAPF------------ 88

Query: 85  PDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPY 144
           P  G S         GGP   P+ PG     P P    P  P  P    AP  P    P 
Sbjct: 89  PPSGPSC-----PPPGGPYPAPTVPGPGPTGPYPTPNMP-FPELPRPYGAPTDPAAAGPL 142

Query: 145 FP--PEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPV-LITLPAE 201
            P      GP A G +G   P   +  P P    GP P PPPP      PPV   T+P  
Sbjct: 143 GPWGSMSSGPWAPG-MGGQYPTPNMPYPSP----GPYPAPPPPQAPGAAPPVPWGTVPPG 197

Query: 202 PTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPG 247
              PP  Y       G +P P     P    Q      G P  P G
Sbjct: 198 AWGPPAPY---PAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPGG 240


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 85/323 (26%), Positives = 99/323 (30%), Gaps = 69/323 (21%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGD 160
           GP G P   G   +       APG P  P  +  PG P    P  PP    P   G  G+
Sbjct: 250 GPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGE 309

Query: 161 AGPAAFVELPLPPLEEGPAPLPPPP----PKENKPPPVLITLPAEPTLPPDAYSHLQGHL 216
            GPA     P    E+GPA LP  P    P  N  P     +P    LP        G  
Sbjct: 310 RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLP--------GPK 361

Query: 217 GHFPGPEPLAFP-VKELQGSGARPGVPLYP--PGLSELKVAEVKEGALLGAGKAKAPKTA 273
           G      P  +P  K  +GS    G P YP  PGL   K          G      PK  
Sbjct: 362 GETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPK----------GNPGLPGPKGD 411

Query: 274 RALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDI---RSLCLP 330
             +  P               PG   P G       P     +G   A  I   R    P
Sbjct: 412 PGVGGP---------------PGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGP 456

Query: 331 EELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKK 390
             +  F  S                     +  P  PGPP    PA I +      T   
Sbjct: 457 PGIPGFPGS---------------------KGDPGSPGPPG---PAGIATKGLNGPTGPP 492

Query: 391 GKPGRKAR--QPAGPASATPPGP 411
           G PG +    +P  P    PPGP
Sbjct: 493 GPPGPRGHSGEPGLPGPPGPPGP 515



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 80/315 (25%), Positives = 98/315 (31%), Gaps = 89/315 (28%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFP--PEGPGPEA-LGF 157
           GPAG    PG      +P   +PGL   P     PG      P  P  P  PG     G 
Sbjct: 66  GPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGP 125

Query: 158 VGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLG 217
            GD GPA             P P  PP P    P P  I++P +P           G  G
Sbjct: 126 KGDVGPAGL-----------PGPRGPPGP-PGIPGPAGISVPGKP-----------GQQG 162

Query: 218 HFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALA 277
               P P  FP     G    PGV    PG++  K  E+  GA    G+           
Sbjct: 163 PTGAPGPRGFP-----GEKGAPGV----PGMNGQK-GEMGYGAPGRPGERG--------- 203

Query: 278 LPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFD 337
                           LPG   P        GP+ P   G    + +      +  +  D
Sbjct: 204 ----------------LPGPQGP-------TGPSGPPGVGKRGENGVPG----QPGIKGD 236

Query: 338 YSVPEILDTVSNVDYFFNFKALDEEQPPHP-GPPATNTPAPILSGKRKASTAKKGKPGRK 396
              P  +  +                PP P GPP    P  I       +  + G PG K
Sbjct: 237 RGFPGEMGPIG---------------PPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTK 281

Query: 397 ARQPAGPASATPPGP 411
              P  P  A PPGP
Sbjct: 282 G-LPGAPGIAGPPGP 295



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 14/91 (15%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGD 160
           GP G P  PG+     +  +  PG+P +P  +  PG P           PGP  +   G 
Sbjct: 440 GPRGAPGIPGT-----RGPIGPPGIPGFPGSKGDPGSPG---------PPGPAGIATKGL 485

Query: 161 AGPAAFVELPLPPLEEGPAPLPPPPPKENKP 191
            GP      P P    G   LP PP     P
Sbjct: 486 NGPTGPPGPPGPRGHSGEPGLPGPPGPPGPP 516



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 6/110 (5%)

Query: 100 GGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG-PEALGFV 158
           GGP G+P   G     P      PG       + APG P    P  PP  PG P + G  
Sbjct: 415 GGPPGLPGPVG-----PAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDP 469

Query: 159 GDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDA 208
           G  GP     +    L     P  PP P+ +   P L   P  P  P  A
Sbjct: 470 GSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQA 519



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 43/152 (28%), Positives = 54/152 (35%), Gaps = 11/152 (7%)

Query: 96  AASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL 155
           A    GPAG+P  PG  L  P   +   G    P     PG      P  P   PG  A 
Sbjct: 321 AKGEQGPAGLPGKPG--LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPG--AK 376

Query: 156 GFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLP-PDAYSHLQG 214
           G  G  G       P  P  +GP   P  P  +  P      +   P LP P   +  +G
Sbjct: 377 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDP-----GVGGPPGLPGPVGPAGAKG 431

Query: 215 HLGHFPGPEPLAFP-VKELQGSGARPGVPLYP 245
             GH     P   P +   +G    PG+P +P
Sbjct: 432 MPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFP 463


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 59/217 (27%), Positives = 76/217 (35%), Gaps = 51/217 (23%)

Query: 85  PDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQP---YLKAPGL---------------- 125
           P LG  A     +   GP+  P  P   LL P P   +LK P                  
Sbjct: 448 PFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFG 507

Query: 126 ---------PPYPHYQQAPGGPQFLLP------YFPPEGPGPEALGFVGDAG-----PAA 165
                    PP PH +   G P           + PP  P P       ++G     PA 
Sbjct: 508 TEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAG 567

Query: 166 FVELPLPPL---EEGPAPLPPPPPKENKPPPVL-ITLPAEPTLPPDAYSHLQGHLGHFPG 221
            V  P PP       P P PP P +  + PP++ +TL   P  P   + +  G       
Sbjct: 568 PVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPES 627

Query: 222 PEP-LAFPVKELQGSGARPGVPL------YPPGLSEL 251
           P P ++FP     G G  PG PL       PPG+ EL
Sbjct: 628 PRPRVSFPKTPEVGPGPPPG-PLSKAPQPVPPGVGEL 663



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 34/105 (32%), Positives = 36/105 (34%), Gaps = 31/105 (29%)

Query: 169 LPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEP-----------TLPPDAYS------- 210
           LPLPP      PLPPPPP    PPP L  L   P           TL  DA+        
Sbjct: 244 LPLPP-----PPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSA 298

Query: 211 --------HLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPG 247
                   H   H   +P P   A P        A PG    PPG
Sbjct: 299 PPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPG 343



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 107/443 (24%), Positives = 145/443 (32%), Gaps = 94/443 (21%)

Query: 26  KGPPNGKVLVASPKQAPRLG-LGPSGSSCSQGTR---LPPTGFQMAPCGCFFDPRIYRIE 81
           +GPP      A P    R G LGP  S  S GT+    PPT                   
Sbjct: 509 EGPPRP----APPPLPHREGFLGPPASRFSVGTQDSHTPPTP------------------ 546

Query: 82  WTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYL--KAPGLPPYPHYQQAPGGPQ 139
             TP    S      ++SG  +  P+ P S+   P PYL      LP  P   Q P  P 
Sbjct: 547 -PTPTTSSSN-----SNSGSHSSSPAGPVSF--PPPPYLARSIDPLPRPPSPAQNPQDPP 598

Query: 140 FL-----LPYFPP--------------EGPGPE-ALGFVGDAGPAAFVELPLPPLEEGPA 179
            +     LP  PP              E P P  +     + GP      P  PL + P 
Sbjct: 599 LVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGP----PPGPLSKAPQ 654

Query: 180 PLPP--------PPPKENKPPPVL---ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFP 228
           P+PP         P   + PP  L      PAE  + PD  +++   L      E     
Sbjct: 655 PVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKE----E 710

Query: 229 VKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAM 288
            ++   +G  P  PL  P  + L+     + A      A A  T            E+  
Sbjct: 711 EQQQHEAGVAPQPPLKEP-FASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEK 769

Query: 289 KLFDCLPGASEPEGTLCEVPGPALPD---SSGGNSADDIRSLCLPEELLSFDY-----SV 340
           K     P A  P   L + P P+ P        + A  ++SL    E   + Y     +V
Sbjct: 770 K----PPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAV 825

Query: 341 PEILDTVSNVDYFFNFKALDEEQPP-HPGPPATNTPAPILSGKRKASTAKKGKP---GRK 396
                 +    Y     +     PP    P A  +P P  S   + ST+  G P    R+
Sbjct: 826 STRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTS--GGPWARERR 883

Query: 397 ARQPAGPASATPPGPREDLGATP 419
           A +   P   TP  P   L   P
Sbjct: 884 AGEEPVPGPMTPTQPPPPLSLPP 906



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 42/154 (27%), Positives = 52/154 (33%), Gaps = 32/154 (20%)

Query: 123 PGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL-------------GFVGDAGPAAFVEL 169
           P LPP P   + P   Q   P  PP  P P +L              + G     +    
Sbjct: 773 PALPPPPPLAKFPPPSQPQPP--PPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPG 830

Query: 170 PLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFP-------GP 222
           PLP  +  P     PP      PP      A+ +  P A S  Q      P       G 
Sbjct: 831 PLPTTQYSPG----PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE 886

Query: 223 EPLAFPVKELQGSGARPGVPL-YPPGLSELKVAE 255
           EP+  P+   Q     P  PL  PP  SE +V E
Sbjct: 887 EPVPGPMTPTQ-----PPPPLSLPPARSESEVLE 915


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 83/339 (24%), Positives = 111/339 (32%), Gaps = 104/339 (30%)

Query: 116  PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG--PEALGFVGDAGPAAF---VELP 170
            P P   A    P PH      G   L    PP  P   P  L       P+A    V L 
Sbjct: 765  PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824

Query: 171  LPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVK 230
             P   +G AP PPPPP    PPP        P +P    +HL+ H      P P   P +
Sbjct: 825  EPATRDG-APQPPPPPP---PPP--------PPMPLQLEAHLRSHGLEPAAPSPRLRPEE 872

Query: 231  ELQGSGARPGV-----PLYPPGLSELKV----AEVKEGALLGAGKAKAPKTARA------ 275
             L   GA   +     PL PP   +  V    +E K+ A  GA ++ +P+  +A      
Sbjct: 873  SLDPPGAMQELLGALEPL-PPAPGDTGVGPPNSEGKDPA--GAYRSPSPQGTKAPRFVPL 929

Query: 276  --LALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEEL 333
              +  PD +L ++    F                  P + +  GG +ADD      PE  
Sbjct: 930  TSICFPDSLLQDEERSFF------------------PTMEEMFGGGAADDYGKAGPPE-- 969

Query: 334  LSFDYSVPEILDTVSNVDYFFNFKALDEEQP-----PHPGPPATNTPAPILSGKRKASTA 388
                                      DE  P     P PGPPA +   P   G+   +  
Sbjct: 970  --------------------------DEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGP 1003

Query: 389  KKGKPGRKARQP----------------AGPASATPPGP 411
            +    G    +P                +GP  A PP P
Sbjct: 1004 ETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPP 1042



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 81/320 (25%), Positives = 97/320 (30%), Gaps = 56/320 (17%)

Query: 129  PHYQQAPGGPQFLLPYFPPEG-PGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPP- 186
            P     P GP    P  P    PGP  L  +  A      E PL  LEE P P PPP P 
Sbjct: 1413 PKDTSTPDGP----PLAPAAAVPGPPPLPGLPSANSNGTPEPPL--LEEKPPPTPPPAPT 1466

Query: 187  -KENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYP 245
             +   PPP     PA P+ PP     L       P P PL  P        A P  P  P
Sbjct: 1467 PQPQPPPPPPPPQPALPSPPP-----LVAPTPSSPPPPPLPPPPPP-----AMPSPPPPP 1516

Query: 246  PGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLC 305
            P  +    A  +E A       + P T R L L  K          D   G S  EG   
Sbjct: 1517 PPAAAPLAAPPEEPAAPSPEDPELPDT-RPLHLAKKQETAAVCGETDEEAGESGGEGIFR 1575

Query: 306  E----------VPGPALPDSSGGNS------------------ADDIRSLCLPEELLS-- 335
            E          +P   L   +G                      D  R  C     L   
Sbjct: 1576 ERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYF 1635

Query: 336  ------FDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAK 389
                  +     + L+ V+  DY          +PP P   +     P+ +G   A   K
Sbjct: 1636 GDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPK 1695

Query: 390  KGKPGRKARQPAGPASATPP 409
               P  K   P    S  PP
Sbjct: 1696 APAPPPKPETPEKTTSEKPP 1715



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 51/182 (28%), Positives = 60/182 (32%), Gaps = 22/182 (12%)

Query: 25   PKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEWTT 84
            P  P  G   V  P    +   G   S   QGT+ P   F      CF D  +   E + 
Sbjct: 889  PLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPR--FVPLTSICFPDSLLQDEERSF 946

Query: 85   PDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPY 144
                +      AA   G AG P   G       P    PG P Y  Y           PY
Sbjct: 947  FPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGP---PPGPPAYDPYG----------PY 993

Query: 145  FP--PEGPGPEALGFVGDAG-----PAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLIT 197
             P    G GPE  G   D       P+     PL  ++ GP    PPPP    PPP   +
Sbjct: 994  CPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPAS 1053

Query: 198  LP 199
             P
Sbjct: 1054 EP 1055



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 49/146 (33%), Positives = 56/146 (38%), Gaps = 30/146 (20%)

Query: 83   TTPDLGQSALYKLAASSGGPA--GVPSA-----PGSYLLEPQPYLKAPGLP-PYPHYQQA 134
            +TPD     L   AA  G P   G+PSA     P   LLE +P    P  P P P     
Sbjct: 1417 STPD--GPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP 1474

Query: 135  PGGPQFLLPYFPP-EGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPP-------PP 186
            P  PQ  LP  PP   P P +        P   +  P PP    P P PPP       PP
Sbjct: 1475 PPPPQPALPSPPPLVAPTPSS-------PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP 1527

Query: 187  KENKPPPVLITLPAEPTLPPDAYSHL 212
            +E   P      P +P LP     HL
Sbjct: 1528 EEPAAPS-----PEDPELPDTRPLHL 1548



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 50/196 (25%), Positives = 68/196 (34%), Gaps = 19/196 (9%)

Query: 47  GPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEWTTP--DLGQSALYKLAASSGGPAG 104
           GP  S  +  + L   G Q  P       +     W T     G + L+ ++ +  G + 
Sbjct: 83  GPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELF-ISGALPGSST 141

Query: 105 VPSA--------PGSYLLEPQPYLKAPGLPPYPHYQQAPG--GPQFLLPYFPPEGPG-PE 153
            PS+        P S+   P P   +  L   P    A G   P  +L   P + P  P 
Sbjct: 142 FPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPS 201

Query: 154 ALGFV-----GDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDA 208
           +LGF      G  GPA       PP   GP   PPPP        +L +  A       +
Sbjct: 202 SLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQS 261

Query: 209 YSHLQGHLGHFPGPEP 224
              L    G  PGP P
Sbjct: 262 SPQLYNFSGAAPGPPP 277



 Score = 33.1 bits (74), Expect = 0.48
 Identities = 66/236 (27%), Positives = 77/236 (32%), Gaps = 59/236 (25%)

Query: 24  PPKGPPNGKVLVAS-----PKQAPRLGLGPSGSSC-----SQGTRLPPTGFQMAPCGCFF 73
           P K  P+G    AS     P+ A   G G  G        S G +    G+  A  G   
Sbjct: 346 PSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGA-- 403

Query: 74  DPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQ 133
                    T P   +S       S GGPA   +             KA G         
Sbjct: 404 ---------TRPPPPRSTATPKCQSLGGPAAAYATG-----------KASGAGGAGGQAY 443

Query: 134 APGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPP 193
           +PG PQ LL        GP+A G     G A   +L   P   G     PP P    PPP
Sbjct: 444 SPGQPQGLL--------GPQAYGQGFGGGQAQ--DLSKAPSYSGG----PPQPPSGPPPP 489

Query: 194 VLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLS 249
            L T     +  PD    LQG L    G EP   P    Q      G+P   P LS
Sbjct: 490 GLATC---QSYSPD---QLQGQLYGVQG-EPYPGPAAHSQ------GLPTASPSLS 532



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 49/170 (28%), Positives = 63/170 (37%), Gaps = 43/170 (25%)

Query: 92  LYKLAASSGGPAGVPSAPGS------------------YLLEPQPYLKAPGLPPYPHYQQ 133
           L K  + SGGP   PS P                    Y ++ +PY   PG  P  H Q 
Sbjct: 469 LSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPY---PG--PAAHSQG 523

Query: 134 APGGPQFLLPYFPPEGP---------GPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPP 184
            P     L  Y     P         GP +LG  G+A P+  +     PL+  PA   PP
Sbjct: 524 LPTASPSL-SYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIR----PLQSPPATGRPP 578

Query: 185 PPKENKPPPVLIT--LPAEPTL-PPDAYSHLQ---GHLGHFPGPEPLAFP 228
                  P   ++  L + P L PP A S+     G+ G   G E LA P
Sbjct: 579 GVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGP 628


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 62/181 (34%), Positives = 72/181 (39%), Gaps = 29/181 (16%)

Query: 100 GGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL---- 155
           GGP G+P  PG     P     A GL   P +  A GGP    P   P   G E      
Sbjct: 683 GGPKGLPGLPG-----PPGPTGAKGLRGIPGFAGADGGPG---PRGLPGDAGREGFPGPP 734

Query: 156 GFVGDAGPAAFVELPLPPLEEGPAPLPPP--PPKENKPPPVLITLPAEPTLPPDAYSHLQ 213
           GF+G  G    V LP P    GP  LP P  PP E   P  +  L A+P    DA    Q
Sbjct: 735 GFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEV--LGAQPGPRGDAGVPGQ 792

Query: 214 GHLGHFPGPE-PLAFPVKE----LQGSGARPGVP-------LY-PPGLSELKVAEVKEGA 260
             L   PG   P  F   +    + G   +PG+P       LY PPGL     A  +EG 
Sbjct: 793 PGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGP 852

Query: 261 L 261
           L
Sbjct: 853 L 853



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 47/154 (30%), Positives = 55/154 (35%), Gaps = 32/154 (20%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKA--------PGLPPYPHYQQAPGGPQFLLPYFPPEGPGP 152
           G AG P  PG     P P L          PG    P  Q  PG P    P     G G 
Sbjct: 338 GEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGD 397

Query: 153 EALGFVGDAGPAAFVELP-LPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSH 211
           +  G  G+ GP  F+  P +P L  GP   P P  K   P P        P LP      
Sbjct: 398 QRRGLPGEMGPKGFIGDPGIPALYGGP---PGPDGKRGPPGP--------PGLPGP---- 442

Query: 212 LQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYP 245
                   PGP+   F +K  +G    PG+P  P
Sbjct: 443 --------PGPDGFLFGLKGAKGRAGFPGLPGSP 468



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 93/358 (25%), Positives = 120/358 (33%), Gaps = 68/358 (18%)

Query: 99  SGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPH--YQQAPGGPQFLLPYFPPEGPGPEALG 156
           S G  G P   G    + +PY     LP      Y+  PG P  +    PP  PG     
Sbjct: 152 SEGFTGPPGPQGPKGQKGEPY----ALPKEERDRYRGEPGEPGLVGFQGPPGRPG----- 202

Query: 157 FVGDAGPAAFVELPLPPLEEGP----------------------APLPPPPPKENKPPPV 194
            VG  GP      P PP   GP                       P P   P +   P  
Sbjct: 203 HVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHP-- 260

Query: 195 LITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVA 254
            I  P   T  PD Y   +G  G  PG   ++  +K  +G    PG+  Y PGLS  K +
Sbjct: 261 -IIAPTGVTFHPDQYKGEKGSEGE-PGIRGIS--LKGEEGIMGFPGLRGY-PGLSGEKGS 315

Query: 255 EVKEGA--LLG----------AGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEG 302
             ++G+  L G           G+A  P      A      L    +     PGA    G
Sbjct: 316 PGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPG 375

Query: 303 TLCEVPGPALPDSSGGNSADDIRSLCLPEEL----LSFDYSVPEILDTVSNVDYFFNFKA 358
           +  E   P LP   G +  D  +   LP E+       D  +P +       D     K 
Sbjct: 376 SQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPD----GKR 431

Query: 359 LDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLG 416
                P  PGPP    P   L G  K +  + G PG     P  P +  P G + D G
Sbjct: 432 GPPGPPGLPGPPG---PDGFLFG-LKGAKGRAGFPG----LPGSPGARGPKGWKGDAG 481



 Score = 35.8 bits (81), Expect = 0.075
 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)

Query: 101 GPAGVPSAPGSYLLE----PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALG 156
           G AGVP  PG   L     P  +  + G+P  P  +  PG P            GP   G
Sbjct: 785 GDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLP------------GPS--G 830

Query: 157 FVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKP 191
             G  GP      P  P +EGP  LP  P +E  P
Sbjct: 831 QPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLP 865



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 50/200 (25%), Positives = 64/200 (32%), Gaps = 32/200 (16%)

Query: 23   RPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEW 82
            R P GPP    L  S         G +G+  + GT  P T       G    P ++ +  
Sbjct: 1295 RGPPGPPGSAALPGSK--------GDTGNPGAPGT--PGTKGWAGDSGPQGRPGVFGLPG 1344

Query: 83   TTPDLGQSALYKLAASSG-----------GPAGVPSAPGSYLLE-----PQPYLKAPGLP 126
                 G+         +G           G  G P APG+         PQ     PG  
Sbjct: 1345 EKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTV 1404

Query: 127  PYPHYQQAPGGPQFLLPYFPPEGPG-PEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP 185
                 +  PG P  + P  PP  PG   A G  G  G      +P    +EGP     P 
Sbjct: 1405 GPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPI 1464

Query: 186  PKENKPPPVLITLPAEPTLP 205
             +E  P       P  P LP
Sbjct: 1465 GQEGAP-----GRPGSPGLP 1479



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 58/218 (26%), Positives = 66/218 (30%), Gaps = 45/218 (20%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGD 160
           G  G+P  PG  +  P      PG P YP      G P  +         GP  LG  G 
Sbjct: 584 GFPGLPGPPGDGIKGP------PGDPGYPGIPGTKGTPGEM---------GPPGLGLPGL 628

Query: 161 AGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFP 220
            G   F          G A LP PP     P P     P +     D    + G      
Sbjct: 629 KGQRGF---------PGDAGLPGPPGFLGPPGPA--GTPGQIDCDTDVKRAVGGDRQEAI 677

Query: 221 GPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPD 280
            P  +  P K L G    PG    P G   L+      GA  G G    P  A     P 
Sbjct: 678 QPGCIGGP-KGLPGLPGPPG----PTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPG 732

Query: 281 KVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGG 318
                         PG   P G+   V  P  PD S G
Sbjct: 733 P-------------PGFIGPRGSKGAVGLPG-PDGSPG 756


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 105/430 (24%), Positives = 142/430 (33%), Gaps = 90/430 (20%)

Query: 38  PKQAPRLGLGPS-GSSCSQGT-RLPPTGFQMAPC--GCFFDPRIYRI-EWTTPDLG-QSA 91
           P ++P   L PS G S   GT  LPP G    P   G    P+  R+    +P     S+
Sbjct: 570 PPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSS 629

Query: 92  LYKLAASSGGPAGVP-SAP-------GSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLP 143
           L  L +SS  PA    S P         +++ P P + AP  PP       P  P    P
Sbjct: 630 LTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPP----PSKPRSPNPAAP 685

Query: 144 YF--PPEGPGPEALGFVGDAGPAAFVELPLPPLEEGP------APLPPPPPKENKPPP-- 193
               P   PGP +        P    +  L PL+E P      +P P PPP  + PPP  
Sbjct: 686 ALAAPAVVPGPVSTTDASPQSPPT-PQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPT 744

Query: 194 ----VLITLPAE-------------PTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSG 236
               V++  P+              P  PP A       +  FP PE   F V     + 
Sbjct: 745 KKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSV-----AS 799

Query: 237 ARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPG 296
             P  P   P L     A       L      +P    A   P               P 
Sbjct: 800 PEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAP--------------APA 845

Query: 297 ASEPEGTLCEVP--GPALPDSSGGNSADDIRSLCLPEELLSF----DYSVPEILDTVSNV 350
           +S P G + ++P   P      GG   +D+ +  +   LL          P    T    
Sbjct: 846 SSAP-GHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT---- 900

Query: 351 DYFFNFKALDEEQPPHP-----GPPATNTPAP---ILSGKRKASTAKKGKPGRKARQPAG 402
                  AL    P  P        A+  PAP   + +  R  + +     G  + QP G
Sbjct: 901 ------PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNG 954

Query: 403 PASATPPGPR 412
           P  A P  P+
Sbjct: 955 PPEAEPRPPQ 964



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 94/397 (23%), Positives = 140/397 (35%), Gaps = 66/397 (16%)

Query: 39  KQAPRLGLGPS--GSSCSQGTRLPPTGFQ-----MAPCGCFFDPRIYRIEWTTPDLGQSA 91
           KQ P+L   P+  GS  +     PP         ++P G    PR       +P+   S 
Sbjct: 528 KQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPR-------SPERTLSP 580

Query: 92  LYKLAASSGGP-------AGVPSAPGSYLLEPQPY----LKAPGLPPYPHYQQAPGGPQF 140
               ++ SG P       AG P++PG     P+P     L++PG                
Sbjct: 581 SSGYSSQSGTPTLPPKGLAGPPASPGK-AQPPKPERVTSLRSPGASVSSSLTSLCSSSS- 638

Query: 141 LLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPA 200
                P +  GP+ L  +GD     FV   +PP  + PAP  PPP K   P P    L A
Sbjct: 639 --DPAPSDRSGPQILTPLGDR----FV---IPPHPKVPAPFSPPPSKPRSPNPAAPAL-A 688

Query: 201 EPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGA 260
            P + P   S         P P+    P++E          P  PP          K+  
Sbjct: 689 APAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPE 748

Query: 261 LLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNS 320
           ++     +AP  +     P    L+D        P   E + ++ + P P          
Sbjct: 749 VV----VEAPSASETAEEP----LQDPNWPPPPPPAPEEQDLSMADFPPP---------- 790

Query: 321 ADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILS 380
            +   S+  PE   +     PE++ + +          +     P P PPA   PAP   
Sbjct: 791 EEAFFSVASPEP--AGPSGSPELVSSPAASSSSATALQIQPPGSPDP-PPAPPAPAP--- 844

Query: 381 GKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGA 417
               AS+A         ++P G +    P PRED+GA
Sbjct: 845 ----ASSAPGHVAKLPQKEPVGCSKGGGP-PREDVGA 876



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 67/264 (25%), Positives = 86/264 (32%), Gaps = 95/264 (35%)

Query: 176 EGPAPLPPPPPKENKPPPVLITLPAEPT-----------LPPDAYSHLQGHLGHFPGPEP 224
           +GP  LPP P ++ +P      LP  PT            PP+  +     L       P
Sbjct: 516 DGPLGLPPKPERKQQP-----QLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRP 570

Query: 225 LAFPVKEL---QGSGARPGVPLYPP-GLSELKVAEVKEGALLGAGKAKAPKTARALALPD 280
              P + L    G  ++ G P  PP GL+         G     GKA+ PK  R  +L  
Sbjct: 571 PRSPERTLSPSSGYSSQSGTPTLPPKGLA---------GPPASPGKAQPPKPERVTSLRS 621

Query: 281 KVLLEDAMKLFDCLPGASEPEG--TLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDY 338
                         PGAS      +LC       P                       D 
Sbjct: 622 --------------PGASVSSSLTSLCSSSSDPAPS----------------------DR 645

Query: 339 SVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKAR 398
           S P+IL  +   D F          PPHP  PA  +P P              KP  ++ 
Sbjct: 646 SGPQILTPLG--DRFV--------IPPHPKVPAPFSPPP-------------SKP--RSP 680

Query: 399 QPAGPASATP---PGPREDLGATP 419
            PA PA A P   PGP     A+P
Sbjct: 681 NPAAPALAAPAVVPGPVSTTDASP 704



 Score = 35.4 bits (80), Expect = 0.098
 Identities = 89/423 (21%), Positives = 140/423 (33%), Gaps = 46/423 (10%)

Query: 5    DKLCVIHHPARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGF 64
            D+  +  HP + P  +   PP   P      A    AP +  GP  ++ +     P    
Sbjct: 656  DRFVIPPHP-KVPAPF--SPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQT 712

Query: 65   QMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPG 124
             + P     +  +   + + P     + +     +  P  V  AP +     +P L+ P 
Sbjct: 713  TLTPLQ---ESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEP-LQDPN 768

Query: 125  LPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPL------------- 171
             PP P    AP      +  FPP      ++     AGP+   EL               
Sbjct: 769  WPPPP--PPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQ 826

Query: 172  --PPLEEGPAPLPPPPPKENKPPPVLITLP-AEPTLPPDAYSHLQGHLGHFPGPEPLAFP 228
              PP    P P PP P   +  P  +  LP  EP          +  +G  P   P    
Sbjct: 827  IQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVG-APLVTPSLLQ 885

Query: 229  VKELQGSGARPGVPLYPPGLSELKVAEVKEGALLG-AGKAKAPKTARALALPDKVLLEDA 287
            +  L+  GA  G P   P L      +    AL G A    AP +           L  A
Sbjct: 886  MVRLRSVGAPGGAP--TPALGPSAPQKPLRRALSGRASPVPAPSSG----------LHAA 933

Query: 288  MKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTV 347
            ++L  C   ASE   +  +  GP   +     S     S    +         P   +T 
Sbjct: 934  VRLKACSLAASEGLSS-AQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQ 992

Query: 348  SNV--DYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPAS 405
            +++  +     +++ E++PP     +   P P+    RK S      P   +   A P +
Sbjct: 993  ADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV---ARKPSVGVP-PPASPSYPRAEPLT 1048

Query: 406  ATP 408
            A P
Sbjct: 1049 APP 1051


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 82/331 (24%), Positives = 115/331 (34%), Gaps = 58/331 (17%)

Query: 102  PAGVPSAPGSYLLEPQPYLKAPG---LPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFV 158
            P GV     S     +P L   G   L P P  ++    P    P  P   P  +     
Sbjct: 1213 PVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP----PLSPERAPEHD---LE 1265

Query: 159  GDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGH 218
             +  P   + LPL P    P P P PP   + PP    T  + P++PP+  +  + H  H
Sbjct: 1266 VEPEPPMMLPLPLQP----PLPPPRPPRPPSPPPEPETTDASHPSVPPEPLA--EDHPPH 1319

Query: 219  FPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALAL 278
             PG   L   + + Q +   P  P   P LS          + L     + P +  +   
Sbjct: 1320 TPG---LCGSLAKSQSTETVPATPGGEPPLS-------GGSSGLSLSSPQVPGSPFSYPA 1369

Query: 279  PDKVLLEDAM-----KLFDCLPGASEPEGTL----CEVPGPALPDSSGGNSADDIRSLCL 329
            P   L    +     + F   P  SEP G L    C +P     + SG  ++  +    L
Sbjct: 1370 PSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGL 1429

Query: 330  PEEL---LSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKAS 386
            P  L   L    ++P +L                + + P P PP    PAP+ S      
Sbjct: 1430 PLPLPLPLPLPLALPAVLRA--------------QARAPTPLPPL--LPAPLAS----CP 1469

Query: 387  TAKKGKPGRKARQPAGPASATPPGPREDLGA 417
               K KPGR  R P    S   P  R   GA
Sbjct: 1470 PPMKRKPGRPRRSPPSMLSLDGPLVRPPAGA 1500



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 79/292 (27%), Positives = 99/292 (33%), Gaps = 53/292 (18%)

Query: 99  SGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPY------FPPEGPGP 152
           +GG +G P     +  +PQ        PP      APG      PY      FPP    P
Sbjct: 360 TGGSSGPP-----FKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEP 414

Query: 153 EALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYS-H 211
            A    G      F   P PP      PLPP  P   + P    T P  P  PPD  S  
Sbjct: 415 TATAAFGARDSGEFRRAPAPP------PLPPAEPLAKEKPG---TPPGPP--PPDTNSME 463

Query: 212 LQGHLGHFPGPEPLAFP-VKELQGSGARPGVPLYP-PGLSELKVAEVKEGALLGAGKAKA 269
           L G       PEP   P    L+ S A P  P        E+ + E +   L      + 
Sbjct: 464 LGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLF----LRE 519

Query: 270 PKTARALALPDKVLLEDAMKLFDCLP-GASEPEGTLCEVPGPALPDSSGGNSADDIRSLC 328
           P +   L +    +   + +L    P G +   G     P  + P S+G    +DI    
Sbjct: 520 PDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTG---LEDISPTP 576

Query: 329 LPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILS 380
           LP      D    E LD             L    PP PGPP    PA +LS
Sbjct: 577 LP------DSDEDEELDL-----------GLGPRPPPEPGPP---DPAGLLS 608



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 36/95 (37%), Positives = 41/95 (43%), Gaps = 8/95 (8%)

Query: 169 LPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFP 228
           LPLPP   G  PLPPPPP    PPP     P  P LPP        H      P PL  P
Sbjct: 679 LPLPP-PPGFPPLPPPPP----PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAP 733

Query: 229 VKELQGSGARPGVPLYPPGLSELKVAEVKEGALLG 263
              +      P +P +PPGL    V +V    +LG
Sbjct: 734 -PGVPPPPILPPLPPFPPGL--FPVMQVDMSHVLG 765



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 110/437 (25%), Positives = 133/437 (30%), Gaps = 147/437 (33%)

Query: 13   PARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCF 72
            P R P     RPP  PP  +   AS    P   L       + G            CG  
Sbjct: 1284 PPRPP-----RPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGL-----------CGSL 1327

Query: 73   FDPRIYRIEWTTPDLGQSALYKLAASSGGPAG-------VPSAPGSYLLEPQPYLKAPGL 125
               +       TP  G+  L      SGG +G       VP +P SY   P P L + GL
Sbjct: 1328 AKSQSTETVPATPG-GEPPL------SGGSSGLSLSSPQVPGSPFSYPA-PSPSLSSGGL 1379

Query: 126  PPYPHYQ-------QAPGGPQFLLPYFP------PEGPGPEALGFVGDAGPAAFVELPLP 172
            P  P            P GP  LLP  P       E  GP A   + + G    + LPLP
Sbjct: 1380 PRTPGRDFSFTPTFSEPSGP-LLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLP 1438

Query: 173  -PLE---------EGPAPLPP---------PPPKENKP-------------------PPV 194
             PL            P PLPP         PPP + KP                   PP 
Sbjct: 1439 LPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPA 1498

Query: 195  -------LITLPAEPTLPPDAYSH------LQGHLGHFPGP-----------------EP 224
                   L+ LP +P  P    +H      L       P P                 EP
Sbjct: 1499 GAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEP 1558

Query: 225  LAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLL 284
               P KEL        +P  P G  E+   E  E A       + PK             
Sbjct: 1559 TKLPFKELDNQWPSEAIPPGPRGRDEV-TEEYMELAKSRGPWRRPPKKRHE--------- 1608

Query: 285  EDAMKLFDCLPGASEPEGTLCEVPGPALPDSS-------------GGNSADDIRSLCLP- 330
                   D +P A  PE      P P     S             GG   +DIR LC+  
Sbjct: 1609 -------DLVPPAGSPE---LSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTY 1658

Query: 331  EELLSFDYSVPEILDTV 347
            E LL  D  +  + DT+
Sbjct: 1659 ERLLQQDNGMDWLNDTL 1675



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 50/163 (30%), Positives = 63/163 (38%), Gaps = 32/163 (19%)

Query: 102 PAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDA 161
           P     A  S L    P    PG PP P     P  PQ   P  PP  P P        A
Sbjct: 664 PGAAAVAAPSVLAPTLPLPPPPGFPPLPP-PPPPPPPQPGFPMPPPLPPPPPP---PPPA 719

Query: 162 GPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPG 221
            PA  V +P PPL        P PP    PPP+   LP  P  PP  +  +Q  + H  G
Sbjct: 720 HPA--VTVPPPPL--------PAPPGV-PPPPI---LPPLPPFPPGLFPVMQVDMSHVLG 765

Query: 222 PE----PLAFPVKE------LQGSGARPGVPLYPPGLSELKVA 254
            +    P++F ++       + G GA P    YPP ++    A
Sbjct: 766 GQWGGMPMSFQMQTQVLSRLMTGQGACP----YPPFMAAAAAA 804


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 70/252 (27%), Positives = 84/252 (33%), Gaps = 78/252 (30%)

Query: 175  EEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQG 234
            + GP  LPPPPP    PP  L  LP  P  PP+  +         P P  L  PV +LQG
Sbjct: 1185 QAGPPELPPPPPPAEPPPTDLAHLP--PLPPPEGEARKPAKPPVSPKP-VLTQPVPKLQG 1241

Query: 235  SGARPG--VPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFD 292
            S       VPL  PG  E+K A        G     +PK       P  V     +    
Sbjct: 1242 SPTPTSKKVPLPGPGSPEVKRAH-------GTPPPVSPKPPPPPTAPKPVKAVAGLPSGS 1294

Query: 293  CLPG-----ASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTV 347
              P      A +P   L + PG   P S G + A                          
Sbjct: 1295 AGPSPAPSPARQPPAALAKPPG--TPPSLGASPA-------------------------- 1326

Query: 348  SNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASAT 407
                           +PP PG PA + PA               KP R A   A  A+A 
Sbjct: 1327 ---------------KPPSPGAPALHVPA---------------KPPR-AAAAAAAAAAA 1355

Query: 408  PPGPREDLGATP 419
            PP P E  GA+P
Sbjct: 1356 PPAPPE--GASP 1365



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 54/193 (27%), Positives = 67/193 (34%), Gaps = 35/193 (18%)

Query: 96   AASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL 155
            A+   GP  +P  P      P      P LPP       P G +   P  PP  P P   
Sbjct: 1182 ASEQAGPPELPPPPPPAEPPPTDLAHLPPLPP-------PEG-EARKPAKPPVSPKP--- 1230

Query: 156  GFVGDAGPAAFVELPLPPLEEGP------APLPPPPPKENK-----PPPVLITLPAEPTL 204
                       +  P+P L+  P       PLP P   E K     PPPV    P  PT 
Sbjct: 1231 ----------VLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTA 1280

Query: 205  PPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGA 264
            P    + + G      GP P   P ++   + A+P  P  PP L          GA    
Sbjct: 1281 PKPVKA-VAGLPSGSAGPSPAPSPARQPPAALAKP--PGTPPSLGASPAKPPSPGAPALH 1337

Query: 265  GKAKAPKTARALA 277
              AK P+ A A A
Sbjct: 1338 VPAKPPRAAAAAA 1350



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 48/184 (26%), Positives = 63/184 (34%), Gaps = 39/184 (21%)

Query: 11   HHPARAPKQYLCRPPKGPP-NGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPC 69
            H P   P +   R P  PP + K ++  P   P+L   P+ +S  +   LP  G      
Sbjct: 1207 HLPPLPPPEGEARKPAKPPVSPKPVLTQP--VPKLQGSPTPTS--KKVPLPGPG------ 1256

Query: 70   GCFFDPRIYRIEWTTPDLGQSA---------LYKLAASSGGPAGVPSAPGSYLLEPQPYL 120
                 P + R   T P +             +  +A    G AG   AP      P    
Sbjct: 1257 ----SPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALA 1312

Query: 121  KAPGLPPY----PHYQQAPGGPQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEE 176
            K PG PP     P    +PG P   +P  PP             A  AA    P PP  E
Sbjct: 1313 KPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAA---------AAAAAAAAPPAPP--E 1361

Query: 177  GPAP 180
            G +P
Sbjct: 1362 GASP 1365



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 39/138 (28%), Positives = 49/138 (35%), Gaps = 34/138 (24%)

Query: 102  PAGVPSAPGSYLLEPQPYLKA-----------PGLPPYPHYQQAPGGPQFLLPYFPPEGP 150
            PA  P +P   L +P P L+            PG P  P  ++A G P  + P  PP   
Sbjct: 1221 PAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPG-PGSPEVKRAHGTPPPVSPKPPPPPT 1279

Query: 151  GPEALGFV-----GDAGP-----------AAFVELPLPPLEEGPAPLPPPPP------KE 188
             P+ +  V     G AGP           AA  + P  P   G +P  PP P        
Sbjct: 1280 APKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVP 1339

Query: 189  NKPPPVLITLPAEPTLPP 206
             KPP       A    PP
Sbjct: 1340 AKPPRAAAAAAAAAAAPP 1357



 Score = 32.7 bits (73), Expect = 0.63
 Identities = 91/409 (22%), Positives = 125/409 (30%), Gaps = 79/409 (19%)

Query: 59   LPPTGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQ- 117
            LPPT   M+P      P      +  P   +  +   AA    P  VP+A  +  L P+ 
Sbjct: 811  LPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGP-AAPGPAPPPVPTAVPTLCLPPEA 869

Query: 118  ------PYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVG-----------D 160
                  P  +A  L  Y      P   + L+P     GP       VG           D
Sbjct: 870  DAEPGRPKKRAHSLNRYAASDSEPERDELLVP--AAAGPYATVQRRVGRSHSVRAPAGAD 927

Query: 161  AGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFP 220
                      + P ++GP   PPPPPK +        L  EP    +    L G      
Sbjct: 928  KNVNRSQSFAVRPRKKGP---PPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCR 984

Query: 221  GPEPLAFPVK--------------ELQGSGA---------------RPGVPLYPPGLSEL 251
                LA  V               EL   G                RP  P   PG    
Sbjct: 985  RASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASP--EPGRVAT 1042

Query: 252  KVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPA 311
             +A VK    +G G  +     R L+ P   LL  A +     PG S         PGP 
Sbjct: 1043 VLASVKHKEAIGPG-GEVVNRRRTLSGPVTGLLATARR----GPGESAD-------PGPF 1090

Query: 312  LPDSSG---------GNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEE 362
            + D +G         G +  +   L   E   +    +    +   NV +        + 
Sbjct: 1091 VEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKR 1150

Query: 363  QPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGP 411
            +P      A   P P LS     +   + +P   A + AGP    PP P
Sbjct: 1151 RPKAKEREAGPEPPPPLSVYHNGTGTVRRRP---ASEQAGPPELPPPPP 1196



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 41/166 (24%), Positives = 53/166 (31%), Gaps = 33/166 (19%)

Query: 174 LEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQ 233
           L+EGPAP  PP           I   + P +P      L     HF  P+    P K   
Sbjct: 729 LDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQT---PTK--- 782

Query: 234 GSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDC 293
               RPG P                   LG     AP TA+    P  +   +       
Sbjct: 783 ---TRPGSP-----------------QALGGPHGPAPATAKVKPTPQLLPPTERPMSPRS 822

Query: 294 LPGASEPEGTLCEVP-------GPALPDSSGGNSADDIRSLCLPEE 332
           LP +    G    +P       GPA P  +       + +LCLP E
Sbjct: 823 LPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPE 868


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 63/244 (25%), Positives = 80/244 (32%), Gaps = 33/244 (13%)

Query: 14  ARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFF 73
           +R+P+    +P   PP G      P   P    GP     ++    PP G    P     
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP----- 162

Query: 74  DPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLP--PYPHY 131
                      P  G +      +  G P G P   G+   +PQ     PG P  P P  
Sbjct: 163 -----------PPQGDNKSRSSRSPPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQG 208

Query: 132 QQAPGGPQFLLPYFPPEGPGPEALGFVGDA-GPAAFVELPLPPLEEGPAPLPPPPPKENK 190
              P GP    P   P+GP P+       A  P    + P P     P   PPPP K   
Sbjct: 209 GNKPQGPP---PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 265

Query: 191 PPPVLITLPAEPTLP-----PDAYSHLQGHLGHFPGPEPLAFPVK---ELQGSGARPGVP 242
           PPP     P  P  P     P      +      P  +P   P +   + QG    PG P
Sbjct: 266 PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325

Query: 243 LYPP 246
             PP
Sbjct: 326 QGPP 329



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 85/341 (24%), Positives = 102/341 (29%), Gaps = 66/341 (19%)

Query: 96  AASSGG--PAGVPSAPGSYLLEPQPYLKAP-GLPPYPHYQQAP---GG--PQFLLPYFPP 147
           A   GG  P G PS PG     P      P G PP P   Q P   GG  PQ   P   P
Sbjct: 39  APPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 98

Query: 148 EGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLP-- 205
           +GP P+         P    + P P     P   PPPP K   PPP     P  P  P  
Sbjct: 99  QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 158

Query: 206 ---PDAYSHLQGHLGHFPGPEPLAFPVK---ELQGSGARPGVPLYPPGLSELK-VAEVKE 258
              P      +      P  +P   P +   + QG    PG P  PP     K       
Sbjct: 159 PQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 218

Query: 259 GALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGG 318
           G   G       K+  A + P K              G ++P+G       P  P   GG
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQ-------GGNQPQGPPPPPGKPQGPPPQGG 271

Query: 319 NSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPI 378
           N                                          + PP PG P    P P 
Sbjct: 272 NK----------------------------------------PQGPPPPGKP--QGPPPQ 289

Query: 379 LSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 419
              K ++S +  GKP     Q        PP P +  G  P
Sbjct: 290 GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 330



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 58/227 (25%), Positives = 72/227 (31%), Gaps = 38/227 (16%)

Query: 23  RPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEW 82
           +P   PP G      P   P    GP     ++    PP G    P              
Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-------------- 224

Query: 83  TTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLP--PYPHYQQAPGGPQF 140
             P  G +      +  G P G P   G+   +PQ     PG P  P P     P GP  
Sbjct: 225 --PPQGDNKSQSARSPPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQGGNKPQGPP- 278

Query: 141 LLPYFPPEGPGPE-ALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLP 199
             P   P+GP P+          P    + P P     P   PPPP K   PPP     P
Sbjct: 279 --PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 336

Query: 200 AEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPP 246
             P  P           G   GP P      + + + + PG P  PP
Sbjct: 337 QGPPPP-----------GKPQGPPPQG--GSKSRSARSPPGKPQGPP 370



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 48/184 (26%), Positives = 60/184 (32%), Gaps = 21/184 (11%)

Query: 23  RPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEW 82
           +P   PP G      P   P    GP     ++    PP G    P              
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-------------- 286

Query: 83  TTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLL 142
             P  G S      +  G P G P   G+    P P    P  PP P     P GP    
Sbjct: 287 --PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPP--- 340

Query: 143 PYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEP 202
           P   P+GP P+  G    +  +   +   PP +EG  P  PPPP    P         +P
Sbjct: 341 PPGKPQGPPPQG-GSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 399

Query: 203 TLPP 206
             PP
Sbjct: 400 QGPP 403



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 96/410 (23%), Positives = 119/410 (29%), Gaps = 97/410 (23%)

Query: 24  PPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQM----APCGCFFDPRIYR 79
           PP G P G      P Q      GP      QG   PP G +     +P G    P    
Sbjct: 73  PPPGKPQGP-----PPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQGP---- 121

Query: 80  IEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQ 139
                P  G +         G P G P   G+    P P    PG P  P  Q       
Sbjct: 122 -----PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPPPQGDNKSRS 172

Query: 140 FLLPYFPPEGPGPEALGFVGDAGPAAFVELPL-PPLEEGPAPLPPPPPKENK-PPPVLIT 197
              P   P+GP P+  G     GP      P  PP + G  P  PPPP + + PPP    
Sbjct: 173 SRSPPGKPQGPPPQ--GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN 230

Query: 198 LPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELK-VAEV 256
                  PP          G   GP P      + QG    PG P  PP     K     
Sbjct: 231 KSQSARSPP----------GKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278

Query: 257 KEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSS 316
             G   G       K+  + + P K              G ++P+G       P  P   
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ-------GGNQPQGPPPPPGKPQGPPPQ 331

Query: 317 GGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPA 376
           GGN                                          + PP PG P    P 
Sbjct: 332 GGNK----------------------------------------PQGPPPPGKP--QGPP 349

Query: 377 PILSGKRKASTAKKGKP-------GRKARQPAGPASATPPGPREDLGATP 419
           P    K +++ +  GKP       G   + P  PA   P  P+      P
Sbjct: 350 PQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 399


>gi|194353976 transcription factor AP-2 epsilon (activating enhancer
           binding protein 2 epsilon) [Homo sapiens]
          Length = 442

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 66/229 (28%), Positives = 87/229 (37%), Gaps = 38/229 (16%)

Query: 102 PAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPE-ALGFVGD 160
           P G+ +A G   L   P       PP  H   A    +F  PYFPP  P P    G   D
Sbjct: 12  PDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPD 71

Query: 161 AGPAAFVELPLPPLEEGPAPLPPPPP------------KENKPPPVLITLPAEP--TLPP 206
           A  AAF  L   P   G APL  P P            + ++ PP L+  PA      P 
Sbjct: 72  AA-AAFPHLAGDPY-GGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPR 129

Query: 207 DAYSHLQGHLGH--FPGPEPLAFPVKELQGSGARPGV----PLYPPGLSELKVAEVKEGA 260
             Y+     L H    G   LA     L G  A PG+     +  PG+S L  + +K   
Sbjct: 130 RDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIK--- 186

Query: 261 LLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPG 309
                  K P  ++A +L    L +D++     + G + P    C VPG
Sbjct: 187 -------KVPIPSKASSLSALSLAKDSL-----VGGITNPGEVFCSVPG 223


>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
          Length = 478

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 58/203 (28%), Positives = 75/203 (36%), Gaps = 26/203 (12%)

Query: 118 PYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPG--PEALGFVGDAGPAAFVELP---LP 172
           P +  PGLPP P     P G   L+P  PP  PG  P   G      P   +  P   +P
Sbjct: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIP 199

Query: 173 PLEEG-PAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPV-K 230
           PL  G P  +PPP P+   PP       A+    P   +         P P+P   PV K
Sbjct: 200 PLMPGMPPGMPPPVPRPGIPP----MTQAQAVSAPGILNRPPAPTATVPAPQP---PVTK 252

Query: 231 ELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKL 290
            L  S  + G P     ++    A     +L  + KA  P TA+A A     +  D   L
Sbjct: 253 PLFPSAGQMGTP-----VTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPL 307

Query: 291 FDCLPGASEPEGTLCEVPGPALP 313
                  +    T  E P P  P
Sbjct: 308 -------NSTPATTTEPPKPTFP 323



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 16/77 (20%)

Query: 125 LPPYPHYQQAPGGPQFLLPYFPPEGP-GPEALGFVGDAGPAAFVELPLPPLEEGPAPLP- 182
           +PP P   Q  G    + P  PP G  G    G  G      ++   +PP  +GP  +P 
Sbjct: 406 MPPQPGIPQQQG----MRPPMPPHGQYGGHHQGMPG------YLPGAMPPYGQGPPMVPP 455

Query: 183 ----PPPPKENKPPPVL 195
               PP P     PPV+
Sbjct: 456 YQGGPPRPPMGMRPPVM 472


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 106/439 (24%), Positives = 137/439 (31%), Gaps = 53/439 (12%)

Query: 13  PARAPKQYLCRPPKGPPNGKVLVASPKQA-PRLGLGPSGSSCSQGT---RLPPTGFQMAP 68
           P   P      PP+ PP    L + P Q  P   L P  +   Q      LPP     AP
Sbjct: 580 PPETPSSIATPPPQAPP---ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL---QAP 633

Query: 69  CGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPY 128
                 P +  +   +P    +    L  +   P   P     +     P +     PP 
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP- 692

Query: 129 PHYQQAPGGPQFLLP--YFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAP--LPPP 184
               QAP  P    P    PP  P    +       P A   L  PPL+  P+P   PP 
Sbjct: 693 ---SQAP--PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747

Query: 185 PPKENKPPPVLITLPAEP-TLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPL 243
            P    PP V   L A P  +PP   + L   +     P P A P        A P  P 
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLP--MSPLAKPPPQAPPALATPPLQALPSPPA 805

Query: 244 YPPGLSELKVAEVKEGALLGAGKAKAPKTARA--LALPDKVLLEDAMKLFDCLP------ 295
             PG +    +     + L     +AP    A  L +P        ++     P      
Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865

Query: 296 GASEPEGTLCEVPGPALPDSSGGNS--------ADDIRSLCLPEELLSFDYSVPE---IL 344
             S P  TL   PGP  P S   +S             +   PEEL  +D S PE     
Sbjct: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD-SGPEGGAAA 924

Query: 345 DTVSNVDYFFNFKALDEEQPPHP----GPPATNTPAPILSGKRKASTAKKGKPGRKARQP 400
               + +      A     P  P    G P    P P  +G   A             + 
Sbjct: 925 SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL------CTIYET 978

Query: 401 AGPASATPPGPREDLGATP 419
            GP SATP     D G +P
Sbjct: 979 EGPESATPAPGALDPGPSP 997



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 41/127 (32%), Positives = 54/127 (42%), Gaps = 10/127 (7%)

Query: 87  LGQSALYKLAASSGGPA--GVPSAPGSYLLEPQPY----LKAPGLPPYPHYQQAPG-GPQ 139
           L  SA    + +  GP+  G P AP ++  +P+P     L+ P + P P    AP  GP 
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAP-AHPSQPKPKGLQALRPPQVTP-PRKDAAPALGPL 299

Query: 140 FLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLP 199
              P   P   G +A         A  +   LPP      PLP  PP  + PP  L TLP
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS-LQTLP 358

Query: 200 AEPTLPP 206
           + P  PP
Sbjct: 359 SPPATPP 365



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 66/260 (25%), Positives = 85/260 (32%), Gaps = 25/260 (9%)

Query: 1   MSPKDKLCVIHHPARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLP 60
           MSP+     +  P+R        PP  PP    L        +  L P+ S  S    + 
Sbjct: 432 MSPRQTQASLTSPSRPAST----PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487

Query: 61  PTGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYL--LEPQP 118
           P   Q         P+        P L   +     +    PA + + P   L  L P P
Sbjct: 488 P--LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545

Query: 119 YLKAPGLPPYPHYQQAPGGPQFLL--PYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEE 176
              A      PH +  P      L  P  P   P PE    +    P A   L  PPL+ 
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605

Query: 177 GPAP------LPPP--------PPKENKP-PPVLITLPAEPTLPPDAYSHLQGHLGHFPG 221
            P+P       PPP        PP +  P PP    L    T  P A + L  HL   P 
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665

Query: 222 PEPLAFPVKELQGSGARPGV 241
             P + PV+      A P V
Sbjct: 666 SPPPSPPVQAPFSPPASPPV 685



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 93/394 (23%), Positives = 127/394 (32%), Gaps = 57/394 (14%)

Query: 36  ASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEWTTPDLGQSALYKL 95
           A+P  +P      SG S     R P    Q  P G     +  R    TP   + A   L
Sbjct: 246 ATPLSSP----ARSGPSARGTPRAPAHPSQPKPKGL----QALRPPQVTPPR-KDAAPAL 296

Query: 96  AASSGGPAGVPSAPGSYLLE-PQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEA 154
              S  P   PS  G+     P P   A  LP        P  P    P  P   P P A
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPA-----TLPPSPPLATP-LPLAPPSPSA 350

Query: 155 LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG 214
                   P +   LP PP      P    PP    PP  +   P+  T+PP    H   
Sbjct: 351 --------PPSLQTLPSPP----ATPPSQAPPSMTTPP--MQAPPSLQTIPPIQVPHSLT 396

Query: 215 HLGHFPGPEPLAFPVKELQGSGARPGVPLYPPGLSELKVAEVKEGALLGAGKAKA----- 269
                  P PLA  +  LQ + +  G P      S L ++  +  A L +    A     
Sbjct: 397 SPSLQAPPSPLA--LSSLQATTSL-GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453

Query: 270 -PKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLC 328
            P     L+LP    L+ ++      P  S     L   P  AL   +  +    + SL 
Sbjct: 454 SPPLQAPLSLPASPPLQTSLS-----PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508

Query: 329 LPEELLSFDYSVPEILDTVSNVDY--FFNFKALDEE---------QPPHPGPPATNTPAP 377
           +P        + P +    +++      N  +L              PH   P    P P
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568

Query: 378 ILSGKRKASTAKKGKPGRKARQP--AGPASATPP 409
           + +     +T     P   A  P  A PA A+PP
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 71/249 (28%), Positives = 88/249 (35%), Gaps = 54/249 (21%)

Query: 12  HP-ARAPKQYLCRP-PKGP-----PNGKVLV--ASPKQAPRLGLGPSGSSCSQGTR---- 58
           HP A +P     RP P GP     P+ +V    A P   P      S SS SQG+     
Sbjct: 528 HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSH 587

Query: 59  -LPPTGFQMAPCGCFFDPRIYRIEWTTPDL-----GQSALYKLAASSGGPAGVPSAP--G 110
             P  G Q AP      P +     T   +        A YK A+  G P     AP  G
Sbjct: 588 PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPG 647

Query: 111 SYLLEPQPYLKAPGLPPY------PHYQ--QAPGGPQFLLPYFPPEGPGPEALGFVGDAG 162
           +Y     P  K PG PP       P Y+    P GP    P  P  GPGP     +  AG
Sbjct: 648 AYKTATPPGYK-PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP-----LPPAG 701

Query: 163 PAAFVELPLPPLEEGPAP-------------------LPPPPPKENKPPPVLITLPAEPT 203
           P+    LP PP      P                    P PP +   PPP ++ +P+  +
Sbjct: 702 PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761

Query: 204 LPPDAYSHL 212
                  HL
Sbjct: 762 QSARFNKHL 770



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 77/299 (25%), Positives = 107/299 (35%), Gaps = 44/299 (14%)

Query: 123 PGLPPYPHYQQAPGGPQFLLPYFPPEGP-GPEALGFVGDAGPAAFVELPLPPLEEGPAPL 181
           PG PP PH Q  PGG   +L   PP GP G  A   VG          P  P+    +  
Sbjct: 210 PGAPP-PHPQLYPGGTGGVLS-GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267

Query: 182 PPPPPKENKPPPVLI---TLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGAR 238
              PP   KPP   +    LP+ P  PP  + H+  +L   P   PL        G GA+
Sbjct: 268 SGAPP--TKPPTTPVGGGNLPSAP--PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQ 323

Query: 239 PGVPLYPP-------GLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLF 291
           P +P + P       G+  L     K   L  +  +  P ++ A A P +          
Sbjct: 324 P-LPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR---------- 372

Query: 292 DCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILD-TVSNV 350
              P +S    +       A   SS  +S+         + L S+ +S P     +VSN 
Sbjct: 373 --FPYSSSSSSS-------AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQ 423

Query: 351 DYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKG--KPGRKARQPAGPASAT 407
              +   +L  +     GPP    P P        S A  G   P   A+  A P  +T
Sbjct: 424 PPKYTQPSLPSQAVWSQGPP----PPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVST 478



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 72/346 (20%), Positives = 112/346 (32%), Gaps = 70/346 (20%)

Query: 93  YKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGG-------PQFLLPYF 145
           +  ++SS   A   S+  S      P+  +  LP YPH    P         P++  P  
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432

Query: 146 PPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLIT-------L 198
           P      +A+   G   P  +  L L      P P PP    ++   P + T        
Sbjct: 433 P-----SQAVWSQGPPPPPPYGRL-LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQ 486

Query: 199 PAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPL-----------YPPG 247
             +           Q H G+   P P AFP   L+G  +    P            YPPG
Sbjct: 487 QQQQQQQQQQQQQQQQHHGNSGPPPPGAFP-HPLEGGSSHHAHPYAMSPSLGSLRPYPPG 545

Query: 248 LSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTL-CE 306
            + L      + +   AG    P ++ + +                   +S  +G+  C 
Sbjct: 546 PAHLPPPH-SQVSYSQAGPNGPPVSSSSNS------------------SSSTSQGSYPCS 586

Query: 307 VPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPH 366
            P P+            + ++      LS       ++ TV++    +         PP 
Sbjct: 587 HPSPSQGPQGAPYPFPPVPTVTTSSATLS------TVIATVASSPAGYK-----TASPPG 635

Query: 367 PGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPR 412
           P P     P+P   G  K +T     PG K   P    + TPPG R
Sbjct: 636 PPPYGKRAPSP---GAYKTAT----PPGYKPGSPPSFRTGTPPGYR 674


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 71/249 (28%), Positives = 88/249 (35%), Gaps = 54/249 (21%)

Query: 12  HP-ARAPKQYLCRP-PKGP-----PNGKVLV--ASPKQAPRLGLGPSGSSCSQGTR---- 58
           HP A +P     RP P GP     P+ +V    A P   P      S SS SQG+     
Sbjct: 528 HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSH 587

Query: 59  -LPPTGFQMAPCGCFFDPRIYRIEWTTPDL-----GQSALYKLAASSGGPAGVPSAP--G 110
             P  G Q AP      P +     T   +        A YK A+  G P     AP  G
Sbjct: 588 PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPG 647

Query: 111 SYLLEPQPYLKAPGLPPY------PHYQ--QAPGGPQFLLPYFPPEGPGPEALGFVGDAG 162
           +Y     P  K PG PP       P Y+    P GP    P  P  GPGP     +  AG
Sbjct: 648 AYKTATPPGYK-PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP-----LPPAG 701

Query: 163 PAAFVELPLPPLEEGPAP-------------------LPPPPPKENKPPPVLITLPAEPT 203
           P+    LP PP      P                    P PP +   PPP ++ +P+  +
Sbjct: 702 PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761

Query: 204 LPPDAYSHL 212
                  HL
Sbjct: 762 QSARFNKHL 770



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 77/299 (25%), Positives = 107/299 (35%), Gaps = 44/299 (14%)

Query: 123 PGLPPYPHYQQAPGGPQFLLPYFPPEGP-GPEALGFVGDAGPAAFVELPLPPLEEGPAPL 181
           PG PP PH Q  PGG   +L   PP GP G  A   VG          P  P+    +  
Sbjct: 210 PGAPP-PHPQLYPGGTGGVLS-GPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267

Query: 182 PPPPPKENKPPPVLI---TLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGAR 238
              PP   KPP   +    LP+ P  PP  + H+  +L   P   PL        G GA+
Sbjct: 268 SGAPP--TKPPTTPVGGGNLPSAP--PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQ 323

Query: 239 PGVPLYPP-------GLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLF 291
           P +P + P       G+  L     K   L  +  +  P ++ A A P +          
Sbjct: 324 P-LPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR---------- 372

Query: 292 DCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILD-TVSNV 350
              P +S    +       A   SS  +S+         + L S+ +S P     +VSN 
Sbjct: 373 --FPYSSSSSSS-------AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQ 423

Query: 351 DYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKKG--KPGRKARQPAGPASAT 407
              +   +L  +     GPP    P P        S A  G   P   A+  A P  +T
Sbjct: 424 PPKYTQPSLPSQAVWSQGPP----PPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVST 478



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 72/346 (20%), Positives = 112/346 (32%), Gaps = 70/346 (20%)

Query: 93  YKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGG-------PQFLLPYF 145
           +  ++SS   A   S+  S      P+  +  LP YPH    P         P++  P  
Sbjct: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432

Query: 146 PPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLIT-------L 198
           P      +A+   G   P  +  L L      P P PP    ++   P + T        
Sbjct: 433 P-----SQAVWSQGPPPPPPYGRL-LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQ 486

Query: 199 PAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGVPL-----------YPPG 247
             +           Q H G+   P P AFP   L+G  +    P            YPPG
Sbjct: 487 QQQQQQQQQQQQQQQQHHGNSGPPPPGAFP-HPLEGGSSHHAHPYAMSPSLGSLRPYPPG 545

Query: 248 LSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTL-CE 306
            + L      + +   AG    P ++ + +                   +S  +G+  C 
Sbjct: 546 PAHLPPPH-SQVSYSQAGPNGPPVSSSSNS------------------SSSTSQGSYPCS 586

Query: 307 VPGPALPDSSGGNSADDIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALDEEQPPH 366
            P P+            + ++      LS       ++ TV++    +         PP 
Sbjct: 587 HPSPSQGPQGAPYPFPPVPTVTTSSATLS------TVIATVASSPAGYK-----TASPPG 635

Query: 367 PGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPR 412
           P P     P+P   G  K +T     PG K   P    + TPPG R
Sbjct: 636 PPPYGKRAPSP---GAYKTAT----PPGYKPGSPPSFRTGTPPGYR 674


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 71/257 (27%), Positives = 92/257 (35%), Gaps = 35/257 (13%)

Query: 26  KGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFFDPRIYRIEWTTP 85
           KG P    L   P +    G+G  G     G   P         G +  P    ++    
Sbjct: 275 KGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGP-----RGDPGSYGSPGFPGLKGELG 329

Query: 86  DLGQSALYKLAASSGGPA--GVPSAPGSYLLEPQPYLKAPGLPPYP-HYQQA----PGGP 138
            +G   L+ L    G P   G P  PG  +  P P    PG P +P  Y +     P GP
Sbjct: 330 LVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGP 389

Query: 139 QFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEG-PAPLPPPPPKENKP-PPVLI 196
             LL       PG    G +G  GP  F  LP  P E G P      P K  KP  P L 
Sbjct: 390 PGLLGR-----PGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLP 444

Query: 197 TLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGAR------------PGVPLY 244
             P    LP  +  +    +G+ PGP+ +   V    G G +            PG P+ 
Sbjct: 445 GAPGLQGLPGSSVIYCS--VGN-PGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPG-PMG 500

Query: 245 PPGLSELKVAEVKEGAL 261
           PPG   L   +  +G L
Sbjct: 501 PPGPPGLPGRQGSKGDL 517



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 47/145 (32%), Positives = 55/145 (37%), Gaps = 10/145 (6%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPP--EGP-GPEALGF 157
           GP G P  PGS+  +     K    PP  H    PGG  F  P  PP   GP GP  LGF
Sbjct: 575 GPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGF 634

Query: 158 VGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLG 217
            G  G      +P  P   GP  L     K  K   +   +       P  +    G  G
Sbjct: 635 PGPPGERGHPGVPGHPGVRGPDGL-----KGQKGDTISCNVTYPGRHGPPGFDGPPGPKG 689

Query: 218 HFPGPEPLAFPVKELQGSGARPGVP 242
            FPGP+  A  +    G   RPG P
Sbjct: 690 -FPGPQG-APGLSGSDGHKGRPGTP 712



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 49/154 (31%), Positives = 59/154 (38%), Gaps = 22/154 (14%)

Query: 101  GPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVGD 160
            G  G+P  PG            PG P  P Y+  PG         P   PGP+  G  G 
Sbjct: 1292 GDCGLPGPPGP-----------PGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQ--GPHGF 1338

Query: 161  AGPAAFVELPLPPLEEGPAPLP-----PPPPKENKPPPVLITLPAEPTL-PPDAYSHLQG 214
             GP     LP PP  +GP  LP     P PP +    P +  LP  P +  P+    L G
Sbjct: 1339 PGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPG 1398

Query: 215  HLGHFPGPEPLAFP-VKELQGSGARPGVPLYPPG 247
              G   GP     P +   +G    PG P  PPG
Sbjct: 1399 MRGP-SGPGCKGEPGLDGRRGVDGVPGSP-GPPG 1430



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 37/108 (34%), Positives = 40/108 (37%), Gaps = 16/108 (14%)

Query: 101 GPAGVPSAPGSYLLEPQPYLKA-PGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEAL---- 155
           G  GVP  PG       P +   PGLP YP    APGG        PP   G + L    
Sbjct: 816 GFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLP 875

Query: 156 ---------GFVGDAGPAAFVELPLPPLEEGPAPLP--PPPPKENKPP 192
                    G  G  GP     LP PP  +GP  LP  P  P E   P
Sbjct: 876 GRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKP 923



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 48/178 (26%), Positives = 58/178 (32%), Gaps = 30/178 (16%)

Query: 99   SGGPAGVPSAPGSYLLEPQPYLKA----------PGLPPYPHYQQAPGGPQFLLPYFPPE 148
            S GP G P   G   L  QP              PG+P  P  +   G P     +    
Sbjct: 1125 SSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKG 1184

Query: 149  GPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLP---PPPPKENK-----------PPPV 194
              G +    + D GP   V +P    E G    P   PP P+  K           P P 
Sbjct: 1185 QKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPA 1244

Query: 195  LITLPAEPTLPPDAYSHLQGHLG-----HFPGPEPLAFPVKELQGSGARPGVPLYPPG 247
              T  A   +P       QG  G       PGP  L   V  L+G     G+P  PPG
Sbjct: 1245 GATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLP-GPPG 1301


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 66/250 (26%), Positives = 81/250 (32%), Gaps = 43/250 (17%)

Query: 14  ARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFF 73
           +R+P+    +P   PP G      P   P    GP     ++    PP G    P     
Sbjct: 87  SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP----- 141

Query: 74  DPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQ 133
                      P  G  +      S   P G P  P      PQ   +  G PP P   Q
Sbjct: 142 -----------PPQGDKS-----RSPRSPPGKPQGP-----PPQGGNQPQGPPPPPGKPQ 180

Query: 134 AP---GG--PQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKE 188
            P   GG  PQ   P   P+GP P+         P    + P P     P   PPPP K 
Sbjct: 181 GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP 240

Query: 189 NKPPPVLITLPAEPTLP-----PDAYSHLQGHLGHFPGPEPLAFPVKE---LQG----SG 236
             PPP     P  P  P     P A    +      P  +P   P +E    QG    +G
Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 300

Query: 237 ARPGVPLYPP 246
             P  P  PP
Sbjct: 301 GNPQQPQAPP 310



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 45/148 (30%), Positives = 54/148 (36%), Gaps = 20/148 (13%)

Query: 100 GGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQAPGGPQFLLPYFPPEGPGPEALGFVG 159
           G P G P   G+    P P  K  G PP     ++P  P        P+GP P+  G   
Sbjct: 55  GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP-----GKPQGPPPQ--GGNQ 107

Query: 160 DAGPAAFVELPL-PPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQGHLGH 218
             GP      P  PP + G  P  PPPP + + PP        P  PP          G 
Sbjct: 108 PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPP----------GK 157

Query: 219 FPGPEPLAFPVKELQGSGARPGVPLYPP 246
             GP P      + QG    PG P  PP
Sbjct: 158 PQGPPPQG--GNQPQGPPPPPGKPQGPP 183



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 53/198 (26%), Positives = 66/198 (33%), Gaps = 32/198 (16%)

Query: 14  ARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCFF 73
           +R+P+    +P   PP G      P   P    GP      +    PP G    P     
Sbjct: 148 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP----- 202

Query: 74  DPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPYPHYQQ 133
                      P  G  +      SS  P G P  P      PQ   +  G PP P   Q
Sbjct: 203 -----------PPQGDKS-----RSSQSPPGKPQGP-----PPQGGNQPQGPPPPPGKPQ 241

Query: 134 AP---GG--PQFLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKE 188
            P   GG  PQ   P   P+GP P   G    +  +   +   PP +EG  P  PPPP  
Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGP-PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAG 300

Query: 189 NKPPPVLITLPAEPTLPP 206
             P         +P  PP
Sbjct: 301 GNPQQPQAPPAGQPQGPP 318



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 16/58 (27%), Positives = 22/58 (37%)

Query: 362 EQPPHPGPPATNTPAPILSGKRKASTAKKGKPGRKARQPAGPASATPPGPREDLGATP 419
           ++P  P PP      P    K ++S +  GKP     Q        PP P +  G  P
Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245


>gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]
          Length = 494

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 63/238 (26%), Positives = 86/238 (36%), Gaps = 47/238 (19%)

Query: 85  PDLGQSALYKLAASSGGPAGVPSA-PGSYLLEPQPYLKAPGLPPYPHYQ----QAPGGPQ 139
           P + Q  L  +  + G P G+P   PG   L P      PG+PP  H+Q    Q+  G  
Sbjct: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGEN 199

Query: 140 FLLPY--FPPEGPGPEALGFVGDAGPAAFVELPLPPLEEG-PAPLPPPPPKENKPPPVLI 196
            ++P     P GPG                   +PPL  G P  +PPP P+   PP    
Sbjct: 200 IMMPMGGMMPPGPG-------------------IPPLMPGMPPGMPPPVPRPGIPP---- 236

Query: 197 TLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPV-KELQGSGARPGVPLYPPGLSELKVAE 255
              A+    P   +         P P+P   PV K L  S  + G P     ++    A 
Sbjct: 237 MTQAQAVSAPGILNRPPAPTATVPAPQP---PVTKPLFPSAGQMGTP-----VTSSSTAS 288

Query: 256 VKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALP 313
               +L  + KA  P TA+A A     +  D   L       +    T  E P P  P
Sbjct: 289 SNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPL-------NSTPATTTEPPKPTFP 339



 Score = 29.3 bits (64), Expect = 7.0
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 16/77 (20%)

Query: 125 LPPYPHYQQAPGGPQFLLPYFPPEGP-GPEALGFVGDAGPAAFVELPLPPLEEGPAPLP- 182
           +PP P   Q  G    + P  PP G  G    G  G      ++   +PP  +GP  +P 
Sbjct: 422 MPPQPGIPQQQG----MRPPMPPHGQYGGHHQGMPG------YLPGAMPPYGQGPPMVPP 471

Query: 183 ----PPPPKENKPPPVL 195
               PP P     PPV+
Sbjct: 472 YQGGPPRPPMGMRPPVM 488


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 59/226 (26%), Positives = 79/226 (34%), Gaps = 34/226 (15%)

Query: 13  PARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCF 72
           PA     ++  PP  P        + K  P L  GPS  S +     PP    ++     
Sbjct: 366 PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS-GPSPFSMNANLPPPPALKPLSSLSTH 424

Query: 73  FDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAP-GL------ 125
             P  +      P L      +   SS  PA  P    S  L P P    P GL      
Sbjct: 425 HPPSAH-----PPPLQLMPQSQPLPSS--PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ 477

Query: 126 PPYPHYQQAPGGPQFLLP------YFPPEGPG----PEALGFVGDAG--------PAAFV 167
           PP+  +   PGGP  + P        PP GPG    P   G     G        P   V
Sbjct: 478 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 537

Query: 168 ELPLPPLEEGPAP-LPPPPPKENKPPPVLITLPAEPTLPPDAYSHL 212
           ++    L++   P  PPPPP+   P P ++  P+  +     Y HL
Sbjct: 538 QIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 583



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 83/317 (26%), Positives = 109/317 (34%), Gaps = 71/317 (22%)

Query: 101 GPAGVPSAP-------------GSYLLEPQPYLKAPG------LPPYPHYQQAPGG--PQ 139
           G AG PSAP             G + L+  P L+ PG      LPP     QAP G  P 
Sbjct: 277 GSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPA 336

Query: 140 FLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP---------PKENK 190
              P+   + P  ++        P    E PLPP       + PPP         P+ +K
Sbjct: 337 AAYPHTSLQLPASQS-ALQSQQPPR---EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 392

Query: 191 PPPVL---------ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGV 241
            PP L           LP  P L P   S L  H  H P   P   P++ +  S   P  
Sbjct: 393 HPPHLSGPSPFSMNANLPPPPALKP--LSSLSTH--HPPSAHPP--PLQLMPQSQPLPSS 446

Query: 242 PLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPE 301
           P  PPGL+        +   L    A  P T      P     +        +PG   P 
Sbjct: 447 PAQPPGLT--------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPF-----VPGGPPPI 493

Query: 302 GTLCEVPGPALPDSSGGNSAD-DIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALD 360
            T    P  + P +  G SA             ++   S P  L TV         +ALD
Sbjct: 494 -TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPTVQ-----IKEEALD 545

Query: 361 EEQPPHPGPPATNTPAP 377
           + + P   PP   +P+P
Sbjct: 546 DAEEPESPPPPPRSPSP 562



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 84/322 (26%), Positives = 109/322 (33%), Gaps = 55/322 (17%)

Query: 97  ASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPY--PHYQQAPGGPQFLLPYFPPEGPGPEA 154
           A S  P G P  P      P P   A  +PP   P   QAP  PQ       P  P P  
Sbjct: 196 APSSAPPGTPQLP-----TPGPTPSATAVPPQGSPTASQAPNQPQ------APTAPVPHT 244

Query: 155 LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG 214
              +  A PA   + P       P+P PPP P  + P   L     +P+ P  A   L G
Sbjct: 245 --HIQQA-PALHPQRP-------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 294

Query: 215 HLGHFPGPEPL-AFPVKELQGSGARPGVPLYPPGLSELKVAEVKEG-ALLGAGKAKA-PK 271
                PGP  L A P+ +       PG P  P GL      +  +G A LG   A A P 
Sbjct: 295 Q--GPPGPHSLQAGPLLQ------HPGPP-QPFGLP----PQASQGQAPLGTSPAAAYPH 341

Query: 272 TARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPE 331
           T+  L      L          LP A      +   P   +P      +      L  P 
Sbjct: 342 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 401

Query: 332 EL-LSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKK 390
              ++ +   P  L  +S         +L    PP   PP    P  ++   +   ++  
Sbjct: 402 PFSMNANLPPPPALKPLS---------SLSTHHPPSAHPP----PLQLMPQSQPLPSSPA 448

Query: 391 GKPGRKARQ--PAGPASATPPG 410
             PG    Q  P  PAS  P G
Sbjct: 449 QPPGLTQSQNLPPPPASHPPTG 470



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 10/72 (13%)

Query: 358 ALDEEQPPHPGPPATNTP----APILSGKRKASTAKKGKPGRKARQPAGPAS--ATP--- 408
           AL  ++PP P PP   +P     P+     + S     +P    + P GP S  A P   
Sbjct: 251 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 310

Query: 409 -PGPREDLGATP 419
            PGP +  G  P
Sbjct: 311 HPGPPQPFGLPP 322


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 59/226 (26%), Positives = 79/226 (34%), Gaps = 34/226 (15%)

Query: 13   PARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCF 72
            PA     ++  PP  P        + K  P L  GPS  S +     PP    ++     
Sbjct: 920  PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS-GPSPFSMNANLPPPPALKPLSSLSTH 978

Query: 73   FDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAP-GL------ 125
              P  +      P L      +   SS  PA  P    S  L P P    P GL      
Sbjct: 979  HPPSAH-----PPPLQLMPQSQPLPSS--PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ 1031

Query: 126  PPYPHYQQAPGGPQFLLP------YFPPEGPG----PEALGFVGDAG--------PAAFV 167
            PP+  +   PGGP  + P        PP GPG    P   G     G        P   V
Sbjct: 1032 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 1091

Query: 168  ELPLPPLEEGPAP-LPPPPPKENKPPPVLITLPAEPTLPPDAYSHL 212
            ++    L++   P  PPPPP+   P P ++  P+  +     Y HL
Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 1137



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 83/317 (26%), Positives = 109/317 (34%), Gaps = 71/317 (22%)

Query: 101  GPAGVPSAP-------------GSYLLEPQPYLKAPG------LPPYPHYQQAPGG--PQ 139
            G AG PSAP             G + L+  P L+ PG      LPP     QAP G  P 
Sbjct: 831  GSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPA 890

Query: 140  FLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP---------PKENK 190
               P+   + P  ++        P    E PLPP       + PPP         P+ +K
Sbjct: 891  AAYPHTSLQLPASQS-ALQSQQPPR---EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 946

Query: 191  PPPVL---------ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGV 241
             PP L           LP  P L P   S L  H  H P   P   P++ +  S   P  
Sbjct: 947  HPPHLSGPSPFSMNANLPPPPALKP--LSSLSTH--HPPSAHPP--PLQLMPQSQPLPSS 1000

Query: 242  PLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPE 301
            P  PPGL+        +   L    A  P T      P     +        +PG   P 
Sbjct: 1001 PAQPPGLT--------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPF-----VPGGPPPI 1047

Query: 302  GTLCEVPGPALPDSSGGNSAD-DIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALD 360
             T    P  + P +  G SA             ++   S P  L TV         +ALD
Sbjct: 1048 -TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPTVQ-----IKEEALD 1099

Query: 361  EEQPPHPGPPATNTPAP 377
            + + P   PP   +P+P
Sbjct: 1100 DAEEPESPPPPPRSPSP 1116



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 84/322 (26%), Positives = 109/322 (33%), Gaps = 55/322 (17%)

Query: 97   ASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPY--PHYQQAPGGPQFLLPYFPPEGPGPEA 154
            A S  P G P  P      P P   A  +PP   P   QAP  PQ       P  P P  
Sbjct: 750  APSSAPPGTPQLP-----TPGPTPSATAVPPQGSPTASQAPNQPQ------APTAPVPHT 798

Query: 155  LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG 214
               +  A PA   + P       P+P PPP P  + P   L     +P+ P  A   L G
Sbjct: 799  --HIQQA-PALHPQRP-------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 848

Query: 215  HLGHFPGPEPL-AFPVKELQGSGARPGVPLYPPGLSELKVAEVKEG-ALLGAGKAKA-PK 271
                 PGP  L A P+ +       PG P  P GL      +  +G A LG   A A P 
Sbjct: 849  Q--GPPGPHSLQAGPLLQ------HPGPP-QPFGLP----PQASQGQAPLGTSPAAAYPH 895

Query: 272  TARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPE 331
            T+  L      L          LP A      +   P   +P      +      L  P 
Sbjct: 896  TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955

Query: 332  EL-LSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKK 390
               ++ +   P  L  +S         +L    PP   PP    P  ++   +   ++  
Sbjct: 956  PFSMNANLPPPPALKPLS---------SLSTHHPPSAHPP----PLQLMPQSQPLPSSPA 1002

Query: 391  GKPGRKARQ--PAGPASATPPG 410
              PG    Q  P  PAS  P G
Sbjct: 1003 QPPGLTQSQNLPPPPASHPPTG 1024



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 10/72 (13%)

Query: 358 ALDEEQPPHPGPPATNTP----APILSGKRKASTAKKGKPGRKARQPAGPAS--ATP--- 408
           AL  ++PP P PP   +P     P+     + S     +P    + P GP S  A P   
Sbjct: 805 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864

Query: 409 -PGPREDLGATP 419
            PGP +  G  P
Sbjct: 865 HPGPPQPFGLPP 876


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 59/226 (26%), Positives = 79/226 (34%), Gaps = 34/226 (15%)

Query: 13   PARAPKQYLCRPPKGPPNGKVLVASPKQAPRLGLGPSGSSCSQGTRLPPTGFQMAPCGCF 72
            PA     ++  PP  P        + K  P L  GPS  S +     PP    ++     
Sbjct: 920  PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS-GPSPFSMNANLPPPPALKPLSSLSTH 978

Query: 73   FDPRIYRIEWTTPDLGQSALYKLAASSGGPAGVPSAPGSYLLEPQPYLKAP-GL------ 125
              P  +      P L      +   SS  PA  P    S  L P P    P GL      
Sbjct: 979  HPPSAH-----PPPLQLMPQSQPLPSS--PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQ 1031

Query: 126  PPYPHYQQAPGGPQFLLP------YFPPEGPG----PEALGFVGDAG--------PAAFV 167
            PP+  +   PGGP  + P        PP GPG    P   G     G        P   V
Sbjct: 1032 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 1091

Query: 168  ELPLPPLEEGPAP-LPPPPPKENKPPPVLITLPAEPTLPPDAYSHL 212
            ++    L++   P  PPPPP+   P P ++  P+  +     Y HL
Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHL 1137



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 83/317 (26%), Positives = 109/317 (34%), Gaps = 71/317 (22%)

Query: 101  GPAGVPSAP-------------GSYLLEPQPYLKAPG------LPPYPHYQQAPGG--PQ 139
            G AG PSAP             G + L+  P L+ PG      LPP     QAP G  P 
Sbjct: 831  GSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPA 890

Query: 140  FLLPYFPPEGPGPEALGFVGDAGPAAFVELPLPPLEEGPAPLPPPP---------PKENK 190
               P+   + P  ++        P    E PLPP       + PPP         P+ +K
Sbjct: 891  AAYPHTSLQLPASQS-ALQSQQPPR---EQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 946

Query: 191  PPPVL---------ITLPAEPTLPPDAYSHLQGHLGHFPGPEPLAFPVKELQGSGARPGV 241
             PP L           LP  P L P   S L  H  H P   P   P++ +  S   P  
Sbjct: 947  HPPHLSGPSPFSMNANLPPPPALKP--LSSLSTH--HPPSAHPP--PLQLMPQSQPLPSS 1000

Query: 242  PLYPPGLSELKVAEVKEGALLGAGKAKAPKTARALALPDKVLLEDAMKLFDCLPGASEPE 301
            P  PPGL+        +   L    A  P T      P     +        +PG   P 
Sbjct: 1001 PAQPPGLT--------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPF-----VPGGPPPI 1047

Query: 302  GTLCEVPGPALPDSSGGNSAD-DIRSLCLPEELLSFDYSVPEILDTVSNVDYFFNFKALD 360
             T    P  + P +  G SA             ++   S P  L TV         +ALD
Sbjct: 1048 -TPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCP--LPTVQ-----IKEEALD 1099

Query: 361  EEQPPHPGPPATNTPAP 377
            + + P   PP   +P+P
Sbjct: 1100 DAEEPESPPPPPRSPSP 1116



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 84/322 (26%), Positives = 109/322 (33%), Gaps = 55/322 (17%)

Query: 97   ASSGGPAGVPSAPGSYLLEPQPYLKAPGLPPY--PHYQQAPGGPQFLLPYFPPEGPGPEA 154
            A S  P G P  P      P P   A  +PP   P   QAP  PQ       P  P P  
Sbjct: 750  APSSAPPGTPQLP-----TPGPTPSATAVPPQGSPTASQAPNQPQ------APTAPVPHT 798

Query: 155  LGFVGDAGPAAFVELPLPPLEEGPAPLPPPPPKENKPPPVLITLPAEPTLPPDAYSHLQG 214
               +  A PA   + P       P+P PPP P  + P   L     +P+ P  A   L G
Sbjct: 799  --HIQQA-PALHPQRP-------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHG 848

Query: 215  HLGHFPGPEPL-AFPVKELQGSGARPGVPLYPPGLSELKVAEVKEG-ALLGAGKAKA-PK 271
                 PGP  L A P+ +       PG P  P GL      +  +G A LG   A A P 
Sbjct: 849  Q--GPPGPHSLQAGPLLQ------HPGPP-QPFGLP----PQASQGQAPLGTSPAAAYPH 895

Query: 272  TARALALPDKVLLEDAMKLFDCLPGASEPEGTLCEVPGPALPDSSGGNSADDIRSLCLPE 331
            T+  L      L          LP A      +   P   +P      +      L  P 
Sbjct: 896  TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955

Query: 332  EL-LSFDYSVPEILDTVSNVDYFFNFKALDEEQPPHPGPPATNTPAPILSGKRKASTAKK 390
               ++ +   P  L  +S         +L    PP   PP    P  ++   +   ++  
Sbjct: 956  PFSMNANLPPPPALKPLS---------SLSTHHPPSAHPP----PLQLMPQSQPLPSSPA 1002

Query: 391  GKPGRKARQ--PAGPASATPPG 410
              PG    Q  P  PAS  P G
Sbjct: 1003 QPPGLTQSQNLPPPPASHPPTG 1024



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 10/72 (13%)

Query: 358 ALDEEQPPHPGPPATNTP----APILSGKRKASTAKKGKPGRKARQPAGPAS--ATP--- 408
           AL  ++PP P PP   +P     P+     + S     +P    + P GP S  A P   
Sbjct: 805 ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ 864

Query: 409 -PGPREDLGATP 419
            PGP +  G  P
Sbjct: 865 HPGPPQPFGLPP 876


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.139    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,838,571
Number of Sequences: 37866
Number of extensions: 2128223
Number of successful extensions: 21110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 353
Number of HSP's successfully gapped in prelim test: 1080
Number of HSP's that attempted gapping in prelim test: 10150
Number of HSP's gapped (non-prelim): 6843
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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