Guide to the Human Genome
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Search of human proteins with 23346427

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23346427 hypothetical protein LOC84221 isoform 2 [Homo
sapiens]
         (186 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|218749820 hypothetical protein LOC84221 isoform 1 [Homo sapiens]   370   e-103
gi|23346427 hypothetical protein LOC84221 isoform 2 [Homo sapiens]    370   e-103
gi|197276668 spermatogenesis and centriole associated 1 isoform ...   156   1e-38
gi|239754974 PREDICTED: similar to spermatogenesis and centriole...    99   2e-21
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    31   0.70 
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    31   0.70 
gi|40068475 twinfilin 1 [Homo sapiens]                                 31   0.70 
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni...    30   0.92 
gi|4502079 adenosine monophosphate deaminase 3 isoform 1A [Homo ...    28   4.6  
gi|70906428 adenosine monophosphate deaminase 3 isoform 1C [Homo...    28   4.6  
gi|70906426 adenosine monophosphate deaminase 3 isoform 1B [Homo...    28   4.6  
gi|33188443 microfilament and actin filament cross-linker protei...    28   5.9  
gi|33188445 microfilament and actin filament cross-linker protei...    28   5.9  
gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo sapi...    27   7.8  
gi|238624193 hypothetical protein LOC221545 isoform 2 [Homo sapi...    27   7.8  
gi|158262031 hypothetical protein LOC221545 isoform 1 [Homo sapi...    27   7.8  

>gi|218749820 hypothetical protein LOC84221 isoform 1 [Homo sapiens]
          Length = 340

 Score =  370 bits (950), Expect = e-103
 Identities = 186/186 (100%), Positives = 186/186 (100%)

Query: 1   MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPG 60
           MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPG
Sbjct: 155 MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPG 214

Query: 61  VTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAF 120
           VTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAF
Sbjct: 215 VTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAF 274

Query: 121 SEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDG 180
           SEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDG
Sbjct: 275 SEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDG 334

Query: 181 KPLFAW 186
           KPLFAW
Sbjct: 335 KPLFAW 340


>gi|23346427 hypothetical protein LOC84221 isoform 2 [Homo sapiens]
          Length = 186

 Score =  370 bits (950), Expect = e-103
 Identities = 186/186 (100%), Positives = 186/186 (100%)

Query: 1   MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPG 60
           MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPG
Sbjct: 1   MVRPKKVCFSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPG 60

Query: 61  VTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAF 120
           VTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAF
Sbjct: 61  VTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAF 120

Query: 121 SEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDG 180
           SEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDG
Sbjct: 121 SEFLINTYGILKQRPDLRANPLHSSPAALRKLVIDVVPPKFLGDSLLLLNCLCELSKEDG 180

Query: 181 KPLFAW 186
           KPLFAW
Sbjct: 181 KPLFAW 186


>gi|197276668 spermatogenesis and centriole associated 1 isoform 1
           [Homo sapiens]
          Length = 591

 Score =  156 bits (394), Expect = 1e-38
 Identities = 79/150 (52%), Positives = 108/150 (72%), Gaps = 5/150 (3%)

Query: 40  RVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQR 99
           R+VGEIAFQLDRRIL+ +FP   RLYGFTV+NIPEKI Q S    D  +DE+  + LTQR
Sbjct: 444 RLVGEIAFQLDRRILSSIFPERVRLYGFTVSNIPEKIIQASLNPSDHKLDEKLCQRLTQR 503

Query: 100 YLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDLRANPLHSSPAA---LRKLVIDV 156
           Y+++  RL+ LGY+  VHPA +E L+N YGIL++RP+L A+     P     L+++V++ 
Sbjct: 504 YVSVMNRLQSLGYNGRVHPALTEQLVNAYGILRERPELAAS--EGGPYTVDFLQRVVVET 561

Query: 157 VPPKFLGDSLLLLNCLCELSKEDGKPLFAW 186
           V P  L D+LLLL+CL +L+ +DGKP+F W
Sbjct: 562 VHPGMLADALLLLSCLSQLAHDDGKPMFIW 591


>gi|239754974 PREDICTED: similar to spermatogenesis and centriole
           associated 1 [Homo sapiens]
          Length = 113

 Score = 99.4 bits (246), Expect = 2e-21
 Identities = 49/112 (43%), Positives = 75/112 (66%), Gaps = 5/112 (4%)

Query: 78  QTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTYGILKQRPDL 137
           + S    D  +DE+  + LTQRY+++  RL+ LGY+  VHPA +E L+N YGIL++RP+L
Sbjct: 4   RASLNPSDHKLDEKLCQRLTQRYVSVMNRLQSLGYNGRVHPALTEQLVNAYGILRERPEL 63

Query: 138 RANPLHSSPAA---LRKLVIDVVPPKFLGDSLLLLNCLCELSKEDGKPLFAW 186
            A+     P     L+++V++ V P  L D+LLLL+CL +L+ +DGKP+F W
Sbjct: 64  AAS--EGGPYTVDFLQRVVVETVHPGMLADALLLLSCLSQLAHDDGKPMFIW 113


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 30.8 bits (68), Expect = 0.70
 Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 72  IPEKIEQTSTKSLDGSVDE--RKLRELTQRYLALSARLEKLGYSRD 115
           +P K+ +   KS D  +D+  RKL ++TQ+Y      +EKL    D
Sbjct: 732 VPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLEND 777


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 30.8 bits (68), Expect = 0.70
 Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 72  IPEKIEQTSTKSLDGSVDE--RKLRELTQRYLALSARLEKLGYSRD 115
           +P K+ +   KS D  +D+  RKL ++TQ+Y      +EKL    D
Sbjct: 745 VPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLEND 790


>gi|40068475 twinfilin 1 [Homo sapiens]
          Length = 384

 Score = 30.8 bits (68), Expect = 0.70
 Identities = 30/144 (20%), Positives = 59/144 (40%), Gaps = 7/144 (4%)

Query: 5   KKVCFSESS---LPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGV 61
           KK   S+SS   L   +   R   +NE+Q+  G +   + +  +AF + R      F  +
Sbjct: 169 KKYLLSQSSPAPLTAAEEELRQIKINEVQTDVGVDTKHQTLQGVAFPISRE----AFQAL 224

Query: 62  TRLYGFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFS 121
            +L    +  +  +I+  +   +  +    +L++L +R    SAR     Y       + 
Sbjct: 225 EKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDSARYHFFLYKHSHEGDYL 284

Query: 122 EFLINTYGILKQRPDLRANPLHSS 145
           E ++  Y +      +R   L+SS
Sbjct: 285 ESIVFIYSMPGYTCSIRERMLYSS 308


>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit
           9A [Homo sapiens]
          Length = 1098

 Score = 30.4 bits (67), Expect = 0.92
 Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 3/95 (3%)

Query: 16  TGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFTVANIPEK 75
           T ++ RR   L E Q +A  + D    GE A   +   +  V PG        V  +PE 
Sbjct: 606 TLEQERRQRELLE-QHYAQYDADDDETGEYATDEEEDEVGPVLPGSDM--AIEVFELPEN 662

Query: 76  IEQTSTKSLDGSVDERKLRELTQRYLALSARLEKL 110
            +  S   LD S    K +EL  ++    A ++KL
Sbjct: 663 EDMFSPSELDTSKLSHKFKELQIKHAVTEAEIQKL 697


>gi|4502079 adenosine monophosphate deaminase 3 isoform 1A [Homo
           sapiens]
          Length = 776

 Score = 28.1 bits (61), Expect = 4.6
 Identities = 28/120 (23%), Positives = 52/120 (43%), Gaps = 11/120 (9%)

Query: 9   FSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFT 68
           F+    P G    R  YL + +++ G E  AR+V E+A +L+     Y  P ++ +YG +
Sbjct: 398 FNSKYNPVGASELRDLYL-KTENYLGGEYFARMVKEVARELEESKYQYSEPRLS-IYGRS 455

Query: 69  VANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTY 128
               P         +L     + K+     R++    R+  +  S+ + P F + L N +
Sbjct: 456 PEEWP---------NLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIF 506


>gi|70906428 adenosine monophosphate deaminase 3 isoform 1C [Homo
           sapiens]
          Length = 774

 Score = 28.1 bits (61), Expect = 4.6
 Identities = 28/120 (23%), Positives = 52/120 (43%), Gaps = 11/120 (9%)

Query: 9   FSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFT 68
           F+    P G    R  YL + +++ G E  AR+V E+A +L+     Y  P ++ +YG +
Sbjct: 396 FNSKYNPVGASELRDLYL-KTENYLGGEYFARMVKEVARELEESKYQYSEPRLS-IYGRS 453

Query: 69  VANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTY 128
               P         +L     + K+     R++    R+  +  S+ + P F + L N +
Sbjct: 454 PEEWP---------NLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIF 504


>gi|70906426 adenosine monophosphate deaminase 3 isoform 1B [Homo
           sapiens]
          Length = 767

 Score = 28.1 bits (61), Expect = 4.6
 Identities = 28/120 (23%), Positives = 52/120 (43%), Gaps = 11/120 (9%)

Query: 9   FSESSLPTGDRTRRSYYLNEIQSFAGAEKDARVVGEIAFQLDRRILAYVFPGVTRLYGFT 68
           F+    P G    R  YL + +++ G E  AR+V E+A +L+     Y  P ++ +YG +
Sbjct: 389 FNSKYNPVGASELRDLYL-KTENYLGGEYFARMVKEVARELEESKYQYSEPRLS-IYGRS 446

Query: 69  VANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLINTY 128
               P         +L     + K+     R++    R+  +  S+ + P F + L N +
Sbjct: 447 PEEWP---------NLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIF 497


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 27.7 bits (60), Expect = 5.9
 Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 66   GFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLI 125
            G  V ++    ++    S  G++ + KL++ T+RY AL ++  +LG       +    L+
Sbjct: 2381 GQKVLDMENSFKEGKEPSEIGNLVKDKLKDATERYTALHSKCTRLG-------SHLNMLL 2433

Query: 126  NTYGILKQRPDLRANPLHSSPAALRKLVIDVV 157
              Y   +   D     + +  A + KL+ D V
Sbjct: 2434 GQYHQFQNSADSLQAWMQACEANVEKLLSDTV 2465


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 27.7 bits (60), Expect = 5.9
 Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 66   GFTVANIPEKIEQTSTKSLDGSVDERKLRELTQRYLALSARLEKLGYSRDVHPAFSEFLI 125
            G  V ++    ++    S  G++ + KL++ T+RY AL ++  +LG       +    L+
Sbjct: 1879 GQKVLDMENSFKEGKEPSEIGNLVKDKLKDATERYTALHSKCTRLG-------SHLNMLL 1931

Query: 126  NTYGILKQRPDLRANPLHSSPAALRKLVIDVV 157
              Y   +   D     + +  A + KL+ D V
Sbjct: 1932 GQYHQFQNSADSLQAWMQACEANVEKLLSDTV 1963


>gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo
           sapiens]
          Length = 496

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 14/49 (28%), Positives = 26/49 (53%), Gaps = 6/49 (12%)

Query: 112 YSRD------VHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVI 154
           Y RD       + A+S F +N+ G++ +    +  P HS P  ++KL++
Sbjct: 427 YKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLV 475


>gi|238624193 hypothetical protein LOC221545 isoform 2 [Homo
           sapiens]
          Length = 181

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 14/49 (28%), Positives = 26/49 (53%), Gaps = 6/49 (12%)

Query: 112 YSRD------VHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVI 154
           Y RD       + A+S F +N+ G++ +    +  P HS P  ++KL++
Sbjct: 112 YKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLV 160


>gi|158262031 hypothetical protein LOC221545 isoform 1 [Homo
           sapiens]
          Length = 315

 Score = 27.3 bits (59), Expect = 7.8
 Identities = 14/49 (28%), Positives = 26/49 (53%), Gaps = 6/49 (12%)

Query: 112 YSRD------VHPAFSEFLINTYGILKQRPDLRANPLHSSPAALRKLVI 154
           Y RD       + A+S F +N+ G++ +    +  P HS P  ++KL++
Sbjct: 246 YKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLV 294


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,800,776
Number of Sequences: 37866
Number of extensions: 267533
Number of successful extensions: 571
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 565
Number of HSP's gapped (non-prelim): 16
length of query: 186
length of database: 18,247,518
effective HSP length: 96
effective length of query: 90
effective length of database: 14,612,382
effective search space: 1315114380
effective search space used: 1315114380
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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