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Search of human proteins with 23238234
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
isoform 2 [Homo sapiens]
(225 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ... 438 e-123
gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ... 424 e-119
gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ... 282 2e-76
gi|21264311 membrane-spanning 4-domains, subfamily A, member 6E ... 144 6e-35
gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i... 133 1e-31
gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i... 133 1e-31
gi|46249347 membrane-spanning 4-domains, subfamily A, member 7 i... 77 2e-14
gi|46249359 membrane-spanning 4-domains, subfamily A, member 7 i... 77 2e-14
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A... 72 3e-13
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A... 72 3e-13
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A... 72 3e-13
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [... 72 3e-13
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [... 69 4e-12
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i... 68 6e-12
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i... 67 2e-11
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i... 67 2e-11
gi|149588599 membrane-spanning 4-domains, subfamily A, member 15... 63 2e-10
gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [... 56 3e-08
gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [... 56 3e-08
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is... 53 2e-07
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ... 52 5e-07
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ... 51 7e-07
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14... 48 8e-06
gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ... 47 1e-05
gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ... 42 6e-04
gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ... 42 6e-04
gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ... 42 6e-04
gi|73486653 membrane-spanning 4-domains, subfamily A, member 3 i... 40 0.002
gi|167466260 membrane-spanning 4-domains, subfamily A, member 10... 39 0.004
gi|16933561 sarcospan isoform 1 [Homo sapiens] 36 0.023
>gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
isoform 2 [Homo sapiens]
Length = 225
Score = 438 bits (1127), Expect = e-123
Identities = 225/225 (100%), Positives = 225/225 (100%)
Query: 1 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
Query: 61 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
Query: 121 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA 180
SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA 180
Query: 181 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGVSVLAGFT 225
SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGVSVLAGFT
Sbjct: 181 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGVSVLAGFT 225
>gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
isoform 1 [Homo sapiens]
Length = 248
Score = 424 bits (1090), Expect = e-119
Identities = 217/217 (100%), Positives = 217/217 (100%)
Query: 1 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
Query: 61 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
Query: 121 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA 180
SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA 180
Query: 181 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG 217
SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG
Sbjct: 181 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG 217
>gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
isoform 3 [Homo sapiens]
Length = 178
Score = 282 bits (721), Expect = 2e-76
Identities = 148/148 (100%), Positives = 148/148 (100%)
Query: 1 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
Query: 61 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61 SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
Query: 121 SILSALSALVGFIILSVKQATLNPASLQ 148
SILSALSALVGFIILSVKQATLNPASLQ
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQ 148
>gi|21264311 membrane-spanning 4-domains, subfamily A, member 6E
[Homo sapiens]
Length = 147
Score = 144 bits (363), Expect = 6e-35
Identities = 77/111 (69%), Positives = 90/111 (81%), Gaps = 1/111 (0%)
Query: 100 SLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTR 159
SL + ++ + VHSSL GSILSALSALVGFI+LSV A LNPASLQC+LD+ +IPTR
Sbjct: 36 SLKKRLQAKVKVIGVHSSLAGSILSALSALVGFILLSVNPAALNPASLQCKLDEKDIPTR 95
Query: 160 SYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQ 210
+SY YH S YT DC+ AKASLAGTLSLML+ T+LEFCLAVLTAVL+WKQ
Sbjct: 96 LLLSYDYH-SPYTMDCHRAKASLAGTLSLMLVSTVLEFCLAVLTAVLQWKQ 145
Score = 94.0 bits (232), Expect = 9e-20
Identities = 47/74 (63%), Positives = 56/74 (75%)
Query: 1 MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
MTSQP+ NETII+LPSNVINFSQAEKPEPTNQGQDSLKK L A++KVIG L G ++
Sbjct: 1 MTSQPISNETIIMLPSNVINFSQAEKPEPTNQGQDSLKKRLQAKVKVIGVHSSLAGSILS 60
Query: 61 SLGIILASASFSPN 74
+L ++ S N
Sbjct: 61 ALSALVGFILLSVN 74
>gi|11139299 membrane-spanning 4-domains, subfamily A, member 7
isoform 1 [Homo sapiens]
Length = 240
Score = 133 bits (334), Expect = 1e-31
Identities = 80/202 (39%), Positives = 111/202 (54%), Gaps = 3/202 (1%)
Query: 19 INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78
I Q EKP Q +D L+ L E V+GT+QILC +++ SLG IL A + +F
Sbjct: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78
Query: 79 TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138
ST L S YPF+G F I+GSLSI + K+ TK SSL + +S+++A G +L+
Sbjct: 79 ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138
Query: 139 QATLNPASLQCELDKNNIPTRSYVSYFYHDSLY-TTDCYTAKASLAGTLSLMLICTLLEF 197
L AS C + + + + Y Y+Y +Y DC SL G L +MLI T+LE
Sbjct: 139 MVALRTASQHCGSEMDYLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLEL 196
Query: 198 CLAVLTAVLRWKQAYSDFPGVS 219
LA ++V WKQ YS+ PG S
Sbjct: 197 LLAAYSSVFWWKQLYSNNPGSS 218
>gi|46249357 membrane-spanning 4-domains, subfamily A, member 7
isoform 1 [Homo sapiens]
Length = 240
Score = 133 bits (334), Expect = 1e-31
Identities = 80/202 (39%), Positives = 111/202 (54%), Gaps = 3/202 (1%)
Query: 19 INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78
I Q EKP Q +D L+ L E V+GT+QILC +++ SLG IL A + +F
Sbjct: 19 ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78
Query: 79 TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138
ST L S YPF+G F I+GSLSI + K+ TK SSL + +S+++A G +L+
Sbjct: 79 ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138
Query: 139 QATLNPASLQCELDKNNIPTRSYVSYFYHDSLY-TTDCYTAKASLAGTLSLMLICTLLEF 197
L AS C + + + + Y Y+Y +Y DC SL G L +MLI T+LE
Sbjct: 139 MVALRTASQHCGSEMDYLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLEL 196
Query: 198 CLAVLTAVLRWKQAYSDFPGVS 219
LA ++V WKQ YS+ PG S
Sbjct: 197 LLAAYSSVFWWKQLYSNNPGSS 218
>gi|46249347 membrane-spanning 4-domains, subfamily A, member 7
isoform 2 [Homo sapiens]
Length = 195
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/126 (38%), Positives = 69/126 (54%), Gaps = 3/126 (2%)
Query: 95 FIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKN 154
F I+GSLSI + K+ TK SSL + +S+++A G +L+ L AS C + +
Sbjct: 50 FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMD 109
Query: 155 NIPTRSYVSYFYHDSLYTT-DCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYS 213
+ + Y Y+Y +Y DC SL G L +MLI T+LE LA ++V WKQ YS
Sbjct: 110 YLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWKQLYS 167
Query: 214 DFPGVS 219
+ PG S
Sbjct: 168 NNPGSS 173
>gi|46249359 membrane-spanning 4-domains, subfamily A, member 7
isoform 2 [Homo sapiens]
Length = 195
Score = 76.6 bits (187), Expect = 2e-14
Identities = 48/126 (38%), Positives = 69/126 (54%), Gaps = 3/126 (2%)
Query: 95 FIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKN 154
F I+GSLSI + K+ TK SSL + +S+++A G +L+ L AS C + +
Sbjct: 50 FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMD 109
Query: 155 NIPTRSYVSYFYHDSLYTT-DCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYS 213
+ + Y Y+Y +Y DC SL G L +MLI T+LE LA ++V WKQ YS
Sbjct: 110 YLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWKQLYS 167
Query: 214 DFPGVS 219
+ PG S
Sbjct: 168 NNPGSS 173
>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 1 [Homo sapiens]
Length = 243
Score = 72.4 bits (176), Expect = 3e-13
Identities = 58/173 (33%), Positives = 87/173 (50%), Gaps = 37/173 (21%)
Query: 38 KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
+K + KV+G ++IL +M LS+GII+ +FS P F V AY G
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112
Query: 93 FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD 152
FIIS SLS+A R TK LV SL +I S++ A+ G +I
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILI------------------ 154
Query: 153 KNNIPTRSYVSYFY----HDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
N + ++ S+ Y HD L +++CY + L GT ++L+ ++LEFC+AV
Sbjct: 155 --NAISLTFYSFRYHYCNHDQL-SSNCYMTMSILMGTDGMVLLLSVLEFCIAV 204
>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 72.4 bits (176), Expect = 3e-13
Identities = 58/173 (33%), Positives = 87/173 (50%), Gaps = 37/173 (21%)
Query: 38 KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
+K + KV+G ++IL +M LS+GII+ +FS P F V AY G
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112
Query: 93 FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD 152
FIIS SLS+A R TK LV SL +I S++ A+ G +I
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILI------------------ 154
Query: 153 KNNIPTRSYVSYFY----HDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
N + ++ S+ Y HD L +++CY + L GT ++L+ ++LEFC+AV
Sbjct: 155 --NAISLTFYSFRYHYCNHDQL-SSNCYMTMSILMGTDGMVLLLSVLEFCIAV 204
>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 72.4 bits (176), Expect = 3e-13
Identities = 58/173 (33%), Positives = 87/173 (50%), Gaps = 37/173 (21%)
Query: 38 KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
+K + KV+G ++IL +M LS+GII+ +FS P F V AY G
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112
Query: 93 FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD 152
FIIS SLS+A R TK LV SL +I S++ A+ G +I
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILI------------------ 154
Query: 153 KNNIPTRSYVSYFY----HDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
N + ++ S+ Y HD L +++CY + L GT ++L+ ++LEFC+AV
Sbjct: 155 --NAISLTFYSFRYHYCNHDQL-SSNCYMTMSILMGTDGMVLLLSVLEFCIAV 204
>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
[Homo sapiens]
Length = 267
Score = 72.4 bits (176), Expect = 3e-13
Identities = 56/164 (34%), Positives = 78/164 (47%), Gaps = 32/164 (19%)
Query: 44 EIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV---TSTLLNSAYPFIGPFFFIISGS 100
E K +G IQI+ G+M + GI+L SFS F +V ST + YPF G FIISGS
Sbjct: 87 EAKALGVIQIMVGLMHIGFGIVLCLISFS--FREVLGFASTAVIGGYPFWGGLSFIISGS 144
Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRS 160
LS++ K L++ LV SL +I+S++ A +G I+L V A
Sbjct: 145 LSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGVAGQD------------ 192
Query: 161 YVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTA 204
Y A S G + ++I +LLEF +A TA
Sbjct: 193 ---------------YWAVLSGKGISATLMIFSLLEFFVACATA 221
>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
[Homo sapiens]
Length = 200
Score = 68.6 bits (166), Expect = 4e-12
Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 4/138 (2%)
Query: 1 MTSQPVPNETIIVLPSNVI--NFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMM 58
M S + +V P + + E T Q L+K ++K++GTIQIL G+M
Sbjct: 1 MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM 60
Query: 59 VLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSL 118
S G+I P + + L S YPF G FI SG+ IA +++ T+ L+ S
Sbjct: 61 TFSFGVIFLFTLLKP-YPRFPFIFL-SGYPFWGSVLFINSGAFLIAVKRKTTETLIILSR 118
Query: 119 VGSILSALSALVGFIILS 136
+ + LSAL A+ G I+L+
Sbjct: 119 IMNFLSALGAIAGIILLT 136
>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
isoform a [Homo sapiens]
Length = 214
Score = 68.2 bits (165), Expect = 6e-12
Identities = 56/186 (30%), Positives = 85/186 (45%), Gaps = 23/186 (12%)
Query: 27 PEPTN----QGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQ-VTST 81
PE N Q D + A+++V+G IQIL M+L+LG+ L S + +F +
Sbjct: 26 PEELNTSVYQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFF 85
Query: 82 LLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQAT 141
+ YP G FF SG+LS+ + T+ + +S +I SA ALVG LS+ A
Sbjct: 86 TFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAV 145
Query: 142 LNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLA-GTLSLMLICTLLEFCLA 200
+ C H S + D S++ G +SL+LI TLLE C+
Sbjct: 146 NIQSLRSC-----------------HSSSESPDLCNYMGSISNGMVSLLLILTLLELCVT 188
Query: 201 VLTAVL 206
+ T +
Sbjct: 189 ISTIAM 194
>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
isoform a [Homo sapiens]
Length = 220
Score = 66.6 bits (161), Expect = 2e-11
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 19/164 (11%)
Query: 38 KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFII 97
+K L E KV+G +QIL +M LS+GI + + + + S + Y G FII
Sbjct: 37 EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIG--YTIWGSVMFII 94
Query: 98 SGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIP 157
SGSLSIA R TK LV SL +I S++ A G +I + A + C
Sbjct: 95 SGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCN------- 147
Query: 158 TRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
+Y +S +C+ + L G ++L+ ++LEFC+AV
Sbjct: 148 -------YYGNS---NNCHGTMSILMGLDGMVLLLSVLEFCIAV 181
>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
isoform b [Homo sapiens]
Length = 239
Score = 66.6 bits (161), Expect = 2e-11
Identities = 53/164 (32%), Positives = 80/164 (48%), Gaps = 19/164 (11%)
Query: 38 KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFII 97
+K L E KV+G +QIL +M LS+GI + + + + S + Y G FII
Sbjct: 56 EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIG--YTIWGSVMFII 113
Query: 98 SGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIP 157
SGSLSIA R TK LV SL +I S++ A G +I + A + C
Sbjct: 114 SGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCN------- 166
Query: 158 TRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
+Y +S +C+ + L G ++L+ ++LEFC+AV
Sbjct: 167 -------YYGNS---NNCHGTMSILMGLDGMVLLLSVLEFCIAV 200
>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
isoform 1 [Homo sapiens]
Length = 240
Score = 63.2 bits (152), Expect = 2e-10
Identities = 47/131 (35%), Positives = 64/131 (48%), Gaps = 9/131 (6%)
Query: 10 TIIVLPSNVINFSQ----AEKPEPTNQGQ-DSLKKHLHAEIKVIGTIQILCGMMVLSLGI 64
T + P ++ F + A+ P T ++ L E KV+GT+QIL G++ L G
Sbjct: 31 TSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGS 90
Query: 65 ILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILS 124
+L V + PF G FIISGSLS+A EK T LV SSL +ILS
Sbjct: 91 VLLMVRRG----HVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILS 146
Query: 125 ALSALVGFIIL 135
++A G IL
Sbjct: 147 VMAAFAGTAIL 157
>gi|23110987 membrane-spanning 4-domains, subfamily A, member 1
[Homo sapiens]
Length = 297
Score = 55.8 bits (133), Expect = 3e-08
Identities = 50/183 (27%), Positives = 83/183 (45%), Gaps = 22/183 (12%)
Query: 44 EIKVIGTIQILCGMMVLSLG--IILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSL 101
E K +G +QI+ G+ ++LG +++ + ++P V YP G +IISGSL
Sbjct: 48 ESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVW-------YPLWGGIMYIISGSL 100
Query: 102 SIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSY 161
ATEK K LV ++ + LS +A+ G +ILS+ S +++ N R++
Sbjct: 101 LAATEKNSRKCLVKGKMIMNSLSLFAAISG-MILSIMDILNIKISHFLKMESLNF-IRAH 158
Query: 162 VSYF-----------YHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQ 210
Y +S T CY+ ++ G LS+MLI + + WK+
Sbjct: 159 TPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKR 218
Query: 211 AYS 213
S
Sbjct: 219 TCS 221
>gi|23110989 membrane-spanning 4-domains, subfamily A, member 1
[Homo sapiens]
Length = 297
Score = 55.8 bits (133), Expect = 3e-08
Identities = 50/183 (27%), Positives = 83/183 (45%), Gaps = 22/183 (12%)
Query: 44 EIKVIGTIQILCGMMVLSLG--IILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSL 101
E K +G +QI+ G+ ++LG +++ + ++P V YP G +IISGSL
Sbjct: 48 ESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVW-------YPLWGGIMYIISGSL 100
Query: 102 SIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSY 161
ATEK K LV ++ + LS +A+ G +ILS+ S +++ N R++
Sbjct: 101 LAATEKNSRKCLVKGKMIMNSLSLFAAISG-MILSIMDILNIKISHFLKMESLNF-IRAH 158
Query: 162 VSYF-----------YHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQ 210
Y +S T CY+ ++ G LS+MLI + + WK+
Sbjct: 159 TPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKR 218
Query: 211 AYS 213
S
Sbjct: 219 TCS 221
>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
isoform 1 [Homo sapiens]
Length = 244
Score = 52.8 bits (125), Expect = 2e-07
Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 17/161 (10%)
Query: 41 LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100
L E + +G QIL M+ L G ++ S + + + YPF G FF ISG
Sbjct: 54 LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113
Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRS 160
LSI +E+R LV SL + S+++ G IL + N + +
Sbjct: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII----------------NLKKSLA 157
Query: 161 YVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
Y+ + T C+ A S + +ML T+L AV
Sbjct: 158 YIHIHSCQKFFETKCFMASFS-TEIVVMMLFLTILGLGSAV 197
>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
isoform 2 [Homo sapiens]
Length = 195
Score = 51.6 bits (122), Expect = 5e-07
Identities = 32/97 (32%), Positives = 47/97 (48%)
Query: 41 LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100
L E + +G QIL M+ L G ++ S + + + YPF G FF ISG
Sbjct: 54 LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113
Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137
LSI +E+R LV SL + S+++ G IL +
Sbjct: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII 150
>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
[Homo sapiens]
Length = 250
Score = 51.2 bits (121), Expect = 7e-07
Identities = 34/92 (36%), Positives = 52/92 (56%), Gaps = 5/92 (5%)
Query: 44 EIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSI 103
E K +G IQI+ G+ + LG I+A+ + S +PF G +FIISGSLS+
Sbjct: 68 EGKTLGAIQIIIGLAHIGLGSIMATVLVG----EYLSISFYGGFPFWGGLWFIISGSLSV 123
Query: 104 ATEKR-LTKLLVHSSLVGSILSALSALVGFII 134
A E + + L+ SL +I+SA+ + VG I+
Sbjct: 124 AAENQPYSYCLLSGSLGLNIVSAICSAVGVIL 155
>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
isoform 1 [Homo sapiens]
Length = 679
Score = 47.8 bits (112), Expect = 8e-06
Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 6/105 (5%)
Query: 36 SLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFF 95
SL L E +V+G QIL ++++ G I A F+Q ++ + YPF G F
Sbjct: 33 SLLDFLKGEPRVLGATQILLALIIVGFGTIFALNYIG--FSQRLPLVVLTGYPFWGALIF 90
Query: 96 IISGSLSIATEKRLTKLLVHSSLVGSILSALSALVG--FIILSVK 138
I++G L++ +K +KLL +++S+L A+ G F ILS +
Sbjct: 91 ILTGYLTVTDKK--SKLLGQGVTGMNVISSLVAITGITFTILSYR 133
>gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
isoform 2 [Homo sapiens]
Length = 147
Score = 47.4 bits (111), Expect = 1e-05
Identities = 27/53 (50%), Positives = 32/53 (60%)
Query: 83 LNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135
+ PF G FIISGSLS+A EK T LV SSL +ILS ++A G IL
Sbjct: 12 IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64
>gi|169202868 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 41.6 bits (96), Expect = 6e-04
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 48 IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
+GT + + +L +G+ ++ +P S YP G +I+SGSLS+ K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201
Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
+ +V+SS+ +I+SAL A G I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229
>gi|169203526 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 41.6 bits (96), Expect = 6e-04
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 48 IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
+GT + + +L +G+ ++ +P S YP G +I+SGSLS+ K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201
Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
+ +V+SS+ +I+SAL A G I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229
>gi|169202217 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 41.6 bits (96), Expect = 6e-04
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 48 IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
+GT + + +L +G+ ++ +P S YP G +I+SGSLS+ K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201
Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
+ +V+SS+ +I+SAL A G I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229
>gi|73486653 membrane-spanning 4-domains, subfamily A, member 3
isoform b [Homo sapiens]
Length = 168
Score = 39.7 bits (91), Expect = 0.002
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 18/113 (15%)
Query: 95 FIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKN 154
F SG+LS+ + T+ + +S +I SA ALVG LS+ A + C
Sbjct: 53 FCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSC----- 107
Query: 155 NIPTRSYVSYFYHDSLYTTDCYTAKASLA-GTLSLMLICTLLEFCLAVLTAVL 206
H S + D S++ G +SL+LI TLLE C+ + T +
Sbjct: 108 ------------HSSSESPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAM 148
>gi|167466260 membrane-spanning 4-domains, subfamily A, member 10
[Homo sapiens]
Length = 267
Score = 38.9 bits (89), Expect = 0.004
Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 37/195 (18%)
Query: 23 QAEKPEPTNQGQDSLKKHLHAE-------IKVIGTIQILCGMMVLSLGIILASASFSPNF 75
Q P+ T Q + L H H + +K +G I ++ L G LAS
Sbjct: 29 QTSAPQNTTQPK-LLAPHQHEKSQKKSSLLKELGAFHITIALLHLVFGGYLASI-----V 82
Query: 76 TQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135
+ +L S YPF G F+ISG L+I + L L+ +++S L G ++
Sbjct: 83 KNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142
Query: 136 SVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLIC-TL 194
S K L P S + Y +S L L L+C T+
Sbjct: 143 S-KDLFLES------------PFESPIWRMYPNSTVHIQ----------RLELALLCFTV 179
Query: 195 LEFCLAVLTAVLRWK 209
LE L V TAV W+
Sbjct: 180 LELFLPVPTAVTAWR 194
>gi|16933561 sarcospan isoform 1 [Homo sapiens]
Length = 243
Score = 36.2 bits (82), Expect = 0.023
Identities = 39/176 (22%), Positives = 72/176 (40%), Gaps = 13/176 (7%)
Query: 47 VIGTIQILCGMMVLSLGIILASASFS--PNFTQVTSTLLNSAYPFIGPFFFIISGSLSIA 104
++ +Q+ G+ V +G ++AS S S T + ++ ++G F +S +
Sbjct: 55 LLALLQLALGIAVTVVGFLMASISSSLLVRDTPFWAGIIVCLVAYLGLFMLCVSYQVDER 114
Query: 105 TEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPA-----SLQCELDKNNIPTR 159
T + + L++ L L+ V F Q T S QC+L + +R
Sbjct: 115 TCIQFSMKLLYFLLSALGLTVCVLAVAFAAHHYSQLTQFTCETTLDSCQCKLPSSEPLSR 174
Query: 160 SYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDF 215
++V Y D TDC + + L + +I L+ + +L + WK Y F
Sbjct: 175 TFV---YRD---VTDCTSVTGTFKLFLLIQMILNLVCGLVCLLACFVMWKHRYQVF 224
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,622,783
Number of Sequences: 37866
Number of extensions: 281867
Number of successful extensions: 692
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 632
Number of HSP's gapped (non-prelim): 41
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.