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Search of human proteins with 225543116
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
(663 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225543116 solute carrier organic anion transporter family, me... 1339 0.0
gi|8394291 solute carrier organic anion transporter family, memb... 1316 0.0
gi|225543118 solute carrier organic anion transporter family, me... 1173 0.0
gi|225543114 solute carrier organic anion transporter family, me... 938 0.0
gi|9790233 solute carrier organic anion transporter family, memb... 546 e-155
gi|225543525 solute carrier organic anion transporter family, me... 540 e-153
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 540 e-153
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 540 e-153
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 482 e-136
gi|222831575 solute carrier organic anion transporter family, me... 373 e-103
gi|222831573 solute carrier organic anion transporter family, me... 373 e-103
gi|188528663 solute carrier organic anion transporter family, me... 329 6e-90
gi|223634012 solute carrier organic anion transporter family, me... 300 4e-81
gi|6005820 solute carrier organic anion transporter family, memb... 300 4e-81
gi|38679890 solute carrier organic anion transporter family, mem... 288 9e-78
gi|225637473 solute carrier organic anion transporter family, me... 283 4e-76
gi|39777594 solute carrier organic anion transporter family memb... 281 1e-75
gi|225637475 solute carrier organic anion transporter family, me... 248 1e-65
gi|223634014 solute carrier organic anion transporter family, me... 233 6e-61
gi|225637477 solute carrier organic anion transporter family, me... 223 3e-58
gi|93277099 solute carrier organic anion transporter family, mem... 194 2e-49
gi|11863156 RECK protein precursor [Homo sapiens] 37 0.076
gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Ho... 32 1.4
gi|9945322 solute carrier family 17, member 7 [Homo sapiens] 32 1.9
gi|12383051 transmembrane protein with EGF-like and two follista... 31 4.2
gi|54873613 agrin [Homo sapiens] 30 5.5
gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo ... 30 5.5
gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [... 30 7.1
gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor [... 30 7.1
gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor [... 30 7.1
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 1339 bits (3466), Expect = 0.0
Identities = 663/663 (100%), Positives = 663/663 (100%)
Query: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE
Sbjct: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
Query: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG
Sbjct: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
Query: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNGCVQ 180
VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNGCVQ
Sbjct: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNGCVQ 180
Query: 181 TVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAA 240
TVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAA
Sbjct: 181 TVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAA 240
Query: 241 VPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNL 300
VPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNL
Sbjct: 241 VPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNL 300
Query: 301 FGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFS 360
FGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFS
Sbjct: 301 FGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFS 360
Query: 361 GGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHE 420
GGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHE
Sbjct: 361 GGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHE 420
Query: 421 RALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAAS 480
RALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAAS
Sbjct: 421 RALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAAS 480
Query: 481 KSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFAL 540
KSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFAL
Sbjct: 481 KSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFAL 540
Query: 541 GIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVIL 600
GIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVIL
Sbjct: 541 GIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVIL 600
Query: 601 GTVSILLSIAVLFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKE 660
GTVSILLSIAVLFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKE
Sbjct: 601 GTVSILLSIAVLFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKE 660
Query: 661 TQL 663
TQL
Sbjct: 661 TQL 663
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 1316 bits (3406), Expect = 0.0
Identities = 663/712 (93%), Positives = 663/712 (93%), Gaps = 49/712 (6%)
Query: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE
Sbjct: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
Query: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG
Sbjct: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
Query: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN---- 176
VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN
Sbjct: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV 180
Query: 177 ---------------------------------------------GCVQTVAIIGPIFGF 191
GCVQTVAIIGPIFGF
Sbjct: 181 DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF 240
Query: 192 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 251
LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP
Sbjct: 241 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 300
Query: 252 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 311
RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC
Sbjct: 301 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 360
Query: 312 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 371
TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS
Sbjct: 361 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 420
Query: 372 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 431
VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC
Sbjct: 421 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 480
Query: 432 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 491
KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR
Sbjct: 481 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 540
Query: 492 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 551
CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA
Sbjct: 541 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 600
Query: 552 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 611
GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV
Sbjct: 601 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAV 660
Query: 612 LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL 663
LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL
Sbjct: 661 LFILKKNYVSKHRSFITKRERTMVSTRFQKENYTTSDHLLQPNYWPGKETQL 712
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 1173 bits (3034), Expect = 0.0
Identities = 590/640 (92%), Positives = 591/640 (92%), Gaps = 49/640 (7%)
Query: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE
Sbjct: 1 MDTSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAE 60
Query: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG
Sbjct: 61 GYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMG 120
Query: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN---- 176
VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN
Sbjct: 121 VGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEV 180
Query: 177 ---------------------------------------------GCVQTVAIIGPIFGF 191
GCVQTVAIIGPIFGF
Sbjct: 181 DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGF 240
Query: 192 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 251
LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP
Sbjct: 241 LLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLP 300
Query: 252 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 311
RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC
Sbjct: 301 RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLC 360
Query: 312 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 371
TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS
Sbjct: 361 TSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRIS 420
Query: 372 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 431
VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC
Sbjct: 421 VCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRC 480
Query: 432 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 491
KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR
Sbjct: 481 KCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGR 540
Query: 492 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 551
CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA
Sbjct: 541 CQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLA 600
Query: 552 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRH 591
GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR+
Sbjct: 601 GIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 640
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 938 bits (2425), Expect = 0.0
Identities = 472/522 (90%), Positives = 473/522 (90%), Gaps = 49/522 (9%)
Query: 119 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN-- 176
MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISN
Sbjct: 1 MGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC 60
Query: 177 -----------------------------------------------GCVQTVAIIGPIF 189
GCVQTVAIIGPIF
Sbjct: 61 EVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIF 120
Query: 190 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 249
GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS
Sbjct: 121 GFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 180
Query: 250 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 309
LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY
Sbjct: 181 LPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLY 240
Query: 310 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 369
LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR
Sbjct: 241 LCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFR 300
Query: 370 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 429
ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS
Sbjct: 301 ISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNS 360
Query: 430 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 489
RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV
Sbjct: 361 RCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIV 420
Query: 490 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 549
GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV
Sbjct: 421 GRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRV 480
Query: 550 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRH 591
LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFR+
Sbjct: 481 LAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 522
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 546 bits (1408), Expect = e-155
Identities = 281/648 (43%), Positives = 403/648 (62%), Gaps = 53/648 (8%)
Query: 26 KTEYPSSEEKQPC--CGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGV 83
KT +S EK+ C K+FL ALSF Y AKAL +K +ITQIERRFDI SSL G+
Sbjct: 9 KTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGL 68
Query: 84 IDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER--- 140
IDGSFEIGNLLVI FVSYFG+KLHRPK+IG GC++MG G++L ++P FFM Y+Y +
Sbjct: 69 IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETH 128
Query: 141 YSPSSNSTLSISPCLL--------------------ESSSQLPVSVM------------- 167
+PS NST S+S CL+ ES S + + V
Sbjct: 129 INPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPI 188
Query: 168 ------------EKSKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITIT 215
++ S + G + + +IGP+ GF LGSL AK+YVDIG+V+L I IT
Sbjct: 189 VPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRIT 248
Query: 216 PKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID-DHT 274
PKD +WVGAWWLG+L++G+ S+++++PF++LPK+ + Q + S K D + T
Sbjct: 249 PKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDDRNQT 308
Query: 275 DYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQ 334
T QG+N + + F SLK++ NP+Y ++L + +Q +S G TY KY+EQQ
Sbjct: 309 ANLTNQGKN--VTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQ 366
Query: 335 YGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLF 394
YGQS+S ANF++G+I IP VA G+F GG ++KKF++S+ G AK +S+ +L L F
Sbjct: 367 YGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYF 426
Query: 395 ALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACL 454
L CE+ VAGLT++Y G V+ H S CNS C C E++WEP+CG NGITY+S CL
Sbjct: 427 PLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCL 486
Query: 455 AGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSY 514
AGC++S+ K+ +FYNC+CV + ++ N S +G C +DN C + F ++ I VI S
Sbjct: 487 AGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSL 546
Query: 515 TLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKR 574
+ GG +L ++ ++P+LK+ A+G ++ IR L GI AP+YFG LID +C+KW
Sbjct: 547 FSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNS 606
Query: 575 CGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSK 622
CG++G+CR+Y+S F +YLGL++ L +++L I +F +KK + K
Sbjct: 607 CGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGK 654
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 540 bits (1392), Expect = e-153
Identities = 274/642 (42%), Positives = 398/642 (61%), Gaps = 51/642 (7%)
Query: 30 PSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFE 89
PS +K C LK+FL ALS + AK L +KS+I IERRF+I SSLVG IDGSFE
Sbjct: 15 PSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFE 74
Query: 90 IGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER---YSPSSN 146
IGNLLVI FVSYFG+KLHRPK+IG GC IMG+G +L A+P FFM Y+Y + + S N
Sbjct: 75 IGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSEN 134
Query: 147 STLSISPCLL--------------------ESSSQLPVSVM------------------- 167
ST ++S CL+ ES S + + V
Sbjct: 135 STSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLS 194
Query: 168 ------EKSKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQW 221
++ S + G + +A+IGPI GF LGSL +K+YVDIG+V+L I ITP D +W
Sbjct: 195 YIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRW 254
Query: 222 VGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID-DHTDYQTPQ 280
VGAWWL +L++G+ S+++++PF++LP++ + Q ++ S + + D T T Q
Sbjct: 255 VGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQ 314
Query: 281 GENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSS 340
G+N I + F S K++ NP+Y +++ + +Q +S G TY KY+EQQYGQ SS
Sbjct: 315 GKN--ITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSS 372
Query: 341 RANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCEN 400
+AN ++G+I IP A G+F GG ++KKF+++ G AK ++V +L F + CEN
Sbjct: 373 KANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCEN 432
Query: 401 SDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTS 460
VAGLT++Y G PV+ H S CNS C C E++WEP+CG NGITY+S CLAGC++S
Sbjct: 433 KSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSS 492
Query: 461 NRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGG 520
+ + K I+FYNC+C+ + ++ N S +G C +D+ C + F +F+ I V+ + +LGG
Sbjct: 493 SGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGG 552
Query: 521 IPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGS 580
+L+++ ++P+LKS ALG +++ IR L GI AP+YFG LIDT+C+KW CG+RGS
Sbjct: 553 TSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGS 612
Query: 581 CRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSK 622
CR Y+S F +YLGL+ +L S++L I +++ +KK Y K
Sbjct: 613 CRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEK 654
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 540 bits (1390), Expect = e-153
Identities = 274/635 (43%), Positives = 394/635 (62%), Gaps = 55/635 (8%)
Query: 26 KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85
+TE + C +LK+FL A++ + +K L+ Y+ S +TQIER+F+IP+SLVG I+
Sbjct: 3 ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62
Query: 86 GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERY---- 141
GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G L ++P F M QY+YE
Sbjct: 63 GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122
Query: 142 -SPSSNSTLSI-------------SPCLLESSSQLPVSVM-------------------- 167
+ SSNS L + S C E S + V V+
Sbjct: 123 GNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISY 182
Query: 168 -----EKSKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWV 222
+ S + G V+T AIIGP+ G LL S CA +YVD GFVN D + ITP D +WV
Sbjct: 183 IEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWV 242
Query: 223 GAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE 282
GAWW G+LI +++L A+PF++LP +LP+ +++ I +++ D Q + +
Sbjct: 243 GAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDKQKEEVK 295
Query: 283 NAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRA 342
K + +DFLP +K+L NP+Y L++ S +QFN+ M+++ PKY+EQQYG SSS A
Sbjct: 296 KEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA 354
Query: 343 NFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSD 402
F++G+ N+P + +G GG++MKKF+I+V AA + S+ YLL+ F + CENS
Sbjct: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414
Query: 403 VAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNR 462
V G+ SY+G Y E +F+DCN C C W+P+CG NG++Y+SACLAGC+TS
Sbjct: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIG 474
Query: 463 SGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIP 522
+G N++F NC+C+ SGNSS ++G C K C M YFL++S ++S+ SL IP
Sbjct: 475 TGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIP 530
Query: 523 GYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCR 582
GY++LLRC+K + KS +G++T RV AGIPAP+YFG L+D++CL WG +CG G+CR
Sbjct: 531 GYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACR 590
Query: 583 LYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617
+YDS FR+IYLGL L S + ++ +L +L+K
Sbjct: 591 IYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 540 bits (1390), Expect = e-153
Identities = 274/635 (43%), Positives = 394/635 (62%), Gaps = 55/635 (8%)
Query: 26 KTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVID 85
+TE + C +LK+FL A++ + +K L+ Y+ S +TQIER+F+IP+SLVG I+
Sbjct: 3 ETEKRIETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFIN 62
Query: 86 GSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERY---- 141
GSFEIGNLL+I FVSYFG KLHRP +IG GCV+MG+G L ++P F M QY+YE
Sbjct: 63 GSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVS 122
Query: 142 -SPSSNSTLSI-------------SPCLLESSSQLPVSVM-------------------- 167
+ SSNS L + S C E S + V V+
Sbjct: 123 GNLSSNSFLCMENGTQILRPTQDPSECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISY 182
Query: 168 -----EKSKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWV 222
+ S + G V+T AIIGP+ G LL S CA +YVD GFVN D + ITP D +WV
Sbjct: 183 IEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWV 242
Query: 223 GAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE 282
GAWW G+LI +++L A+PF++LP +LP+ +++ I +++ D Q + +
Sbjct: 243 GAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD-------IIKNENEDKQKEEVK 295
Query: 283 NAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRA 342
K + +DFLP +K+L NP+Y L++ S +QFN+ M+++ PKY+EQQYG SSS A
Sbjct: 296 KEKY-GITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDA 354
Query: 343 NFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSD 402
F++G+ N+P + +G GG++MKKF+I+V AA + S+ YLL+ F + CENS
Sbjct: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414
Query: 403 VAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNR 462
V G+ SY+G Y E +F+DCN C C W+P+CG NG++Y+SACLAGC+TS
Sbjct: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIG 474
Query: 463 SGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIP 522
+G N++F NC+C+ SGNSS ++G C K C M YFL++S ++S+ SL IP
Sbjct: 475 TGINMVFQNCSCI----QTSGNSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIP 530
Query: 523 GYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCR 582
GY++LLRC+K + KS +G++T RV AGIPAP+YFG L+D++CL WG +CG G+CR
Sbjct: 531 GYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACR 590
Query: 583 LYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617
+YDS FR+IYLGL L S + ++ +L +L+K
Sbjct: 591 IYDSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 482 bits (1240), Expect = e-136
Identities = 243/606 (40%), Positives = 370/606 (61%), Gaps = 50/606 (8%)
Query: 63 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG 122
+K + TQIERRF+I SSLVG+IDGSFEIGNL VI FVSYFG+KLHRPK+IG GC +MG G
Sbjct: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
Query: 123 TLLIAMPQFFMEQYKYERYS---PSSNSTLSISPCLLE---SSSQLPVSVMEKSKSKISN 176
++L+A+P FFM Y+Y + + PS NST ++ CL+ S ++ P ++E+ K S
Sbjct: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG 120
Query: 177 ------------------------------------------GCVQTVAIIGPIFGFLLG 194
G V + + G +F F+LG
Sbjct: 121 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG 180
Query: 195 SLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQ 254
SL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++GI+S+++++PF++LP + P
Sbjct: 181 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLN-PNKP 239
Query: 255 SREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTST 314
+E S D I + F SLK++ NP+Y +++ +
Sbjct: 240 QKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTL 299
Query: 315 VQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCG 374
+ +S +TY K +EQQYG S+S+ NF++G++ +PAVA+G+FSGG ++KKF++S+ G
Sbjct: 300 LHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVG 359
Query: 375 AAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCS 434
AKL S+ L + F L CE+ VAGLT++Y G PV H S CNS C C
Sbjct: 360 LAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCD 419
Query: 435 ETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQK 494
E++WEP+CG NGITY+S CLAGC++S+ + + I+FYNC+CV + ++ N S +G C +
Sbjct: 420 ESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPR 479
Query: 495 DNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIP 554
D+ C + + VI V+ ++ ++G +L++R ++P+LK+ A+G +++ +R L GI
Sbjct: 480 DDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGIL 539
Query: 555 APVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTV-ILGTVSILLSIAVLF 613
P+YFG LIDT+C+KW CG+RG+CR+Y+S + GL V ++ V +LL++ +
Sbjct: 540 VPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFV 599
Query: 614 ILKKNY 619
+ KK++
Sbjct: 600 VRKKSH 605
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 373 bits (958), Expect = e-103
Identities = 215/662 (32%), Positives = 349/662 (52%), Gaps = 78/662 (11%)
Query: 33 EEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGN 92
++K C +K+FL + + A+ YL S +T +ERRF++ S+ VGVI SFEIGN
Sbjct: 30 KKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGN 89
Query: 93 LLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYE------------- 139
L +I FVSYFGA+ HRP++IG G ++M +G LL A+P+F QYKYE
Sbjct: 90 LALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDV 149
Query: 140 --------------------RYSPSSNSTLSISPCLLESSSQLPVSVM---------EKS 170
R + + L I +L PV + +
Sbjct: 150 CAANGSGGDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRK 209
Query: 171 KSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYL 230
S + G + T+ + GP GF+LGS C K+YVD F++ ++ ITP DP+W+GAWW G+L
Sbjct: 210 DSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFL 269
Query: 231 IAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGEN------- 283
+ G + +++ + P+SLP S + E + ++ + +Y+ P+ N
Sbjct: 270 LCGALLFFSSLLMFGFPQSLP-----PHSEPAMESEQAMLSER-EYERPKPSNGVLRHPL 323
Query: 284 -----AKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQS 338
A + R K+L NPV+ + + ++ + G + KY+EQQ+ +
Sbjct: 324 EPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLT 383
Query: 339 SSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGC 398
+S AN ++G+ IP LGIF GG+++KK +S GA ++ + ++ ++S LGC
Sbjct: 384 TSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGC 443
Query: 399 ENSDVAGLTVSY-QGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGC 457
+ VAG+TV Y T P S + +S CN+ C+C + P+CG +GITY+SAC AGC
Sbjct: 444 DTGPVAGVTVPYGNSTAPGSALDP--YSPCNNNCECQTDSFTPVCGADGITYLSACFAGC 501
Query: 458 QTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLS 517
++N +G C C+ ++ N++ + G+C GC + FL FL + I S +
Sbjct: 502 NSTNLTG-------CACLTTVPAE--NATVVPGKCPSP-GCQEAFLTFLCVMCICSLIGA 551
Query: 518 LGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGS 577
+ P I+L+R + P+LKS+ALG+ L +R+L IP P+ FG ID++CL W CG
Sbjct: 552 MAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGE 610
Query: 578 RGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSKHRSFITKRERTMVST 637
+G+C LYD+ V+R++Y+ + + L + + +L L+KNY + +I E + ++
Sbjct: 611 QGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNY----KRYIKNHEGGLSTS 666
Query: 638 RF 639
F
Sbjct: 667 EF 668
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 373 bits (957), Expect = e-103
Identities = 212/642 (33%), Positives = 341/642 (53%), Gaps = 74/642 (11%)
Query: 33 EEKQPCCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGN 92
++K C +K+FL + + A+ YL S +T +ERRF++ S+ VGVI SFEIGN
Sbjct: 30 KKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGN 89
Query: 93 LLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYE------------- 139
L +I FVSYFGA+ HRP++IG G ++M +G LL A+P+F QYKYE
Sbjct: 90 LALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDV 149
Query: 140 --------------------RYSPSSNSTLSISPCLLESSSQLPVSVM---------EKS 170
R + + L I +L PV + +
Sbjct: 150 CAANGSGGDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRK 209
Query: 171 KSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYL 230
S + G + T+ + GP GF+LGS C K+YVD F++ ++ ITP DP+W+GAWW G+L
Sbjct: 210 DSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFL 269
Query: 231 IAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGEN------- 283
+ G + +++ + P+SLP S + E + ++ + +Y+ P+ N
Sbjct: 270 LCGALLFFSSLLMFGFPQSLP-----PHSEPAMESEQAMLSER-EYERPKPSNGVLRHPL 323
Query: 284 -----AKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQS 338
A + R K+L NPV+ + + ++ + G + KY+EQQ+ +
Sbjct: 324 EPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLT 383
Query: 339 SSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGC 398
+S AN ++G+ IP LGIF GG+++KK +S GA ++ + ++ ++S LGC
Sbjct: 384 TSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGC 443
Query: 399 ENSDVAGLTVSY-QGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGC 457
+ VAG+TV Y T P S + +S CN+ C+C + P+CG +GITY+SAC AGC
Sbjct: 444 DTGPVAGVTVPYGNSTAPGSALDP--YSPCNNNCECQTDSFTPVCGADGITYLSACFAGC 501
Query: 458 QTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLS 517
++N +G C C+ ++ N++ + G+C GC + FL FL + I S +
Sbjct: 502 NSTNLTG-------CACLTTVPAE--NATVVPGKCPSP-GCQEAFLTFLCVMCICSLIGA 551
Query: 518 LGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGS 577
+ P I+L+R + P+LKS+ALG+ L +R+L IP P+ FG ID++CL W CG
Sbjct: 552 MAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGE 610
Query: 578 RGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNY 619
+G+C LYD+ V+R++Y+ + + L + + +L L+KNY
Sbjct: 611 QGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNY 652
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 329 bits (843), Expect = 6e-90
Identities = 191/629 (30%), Positives = 313/629 (49%), Gaps = 76/629 (12%)
Query: 40 GELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFV 99
G +KVF+ + + L Y KS++T IE+RF + SS G+I EI N ++I FV
Sbjct: 29 GNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFV 88
Query: 100 SYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPC----- 154
SYFG+++HRP++IG G + + G ++ +P F E Y+Y S +NS L C
Sbjct: 89 SYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRLQAELCQKHWQ 148
Query: 155 -----------------------------LLESSSQLPVSVM---------EKSKSKISN 176
LL +P+ E S S +
Sbjct: 149 DLPPSKCHSTTQNPQKETSSMWGLMVVAQLLAGIGTVPIQPFGISYVDDFSEPSNSPLYI 208
Query: 177 GCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIIS 236
+ +++ GP FG+LLGS+ +++VD G VN + + P DP+W+GAWWLG LI+ +
Sbjct: 209 SILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIGAWWLGLLISSALL 268
Query: 237 LLAAVPFWYLPKSLP----RSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARD 292
+L + PF++ P+++P R+ + D E++K +++ +
Sbjct: 269 VLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAK--------------SRGSLVDFIKR 314
Query: 293 FLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIP 352
F L N ++ L + + + G+ T+ K++E+QYG S++ ANF+IG +N+P
Sbjct: 315 FPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLP 374
Query: 353 AVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQG 412
A ALG+ GGI+MK+F S+ ++ +L + LF +GC VA + Y
Sbjct: 375 AAALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEV---YPP 431
Query: 413 TKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRS---GKNIIF 469
+ S H ++ C C C ++ + P+CG+NGI Y+S C AGC N S K +I+
Sbjct: 432 STSSSIHPQS--PACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIY 489
Query: 470 YNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLR 529
NC+CV G++S G C C L + + S + P Y+++LR
Sbjct: 490 LNCSCV-----TGGSASAKTGSCPVP--CAHFLLPAIFLISFVSLIACISHNPLYMMVLR 542
Query: 530 CIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVF 589
+ + KSFA+G+ L +R+LA +P+P +G+ ID SC++W G RG+C YD++
Sbjct: 543 VVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNSLCLGRRGACAYYDNDAL 602
Query: 590 RHIYLGLTVILGTVSILLSIAVLFILKKN 618
R YLGL + + +LL + + +KKN
Sbjct: 603 RDRYLGLQMGYKALGMLLLCFISWRVKKN 631
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 300 bits (767), Expect = 4e-81
Identities = 186/642 (28%), Positives = 315/642 (49%), Gaps = 80/642 (12%)
Query: 42 LKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+K+F+ S + A+ + GYLKS+I+ +E+RF + S G++ E+GN +I FVSY
Sbjct: 26 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 85
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSS 160
FG+++HRP++IG G +++ + LL+ +P F E Y+Y+ SP S CL +S+
Sbjct: 86 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 145
Query: 161 QLP------------------VSVM--------------------------EKSKSKISN 176
V +M S S +
Sbjct: 146 PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYL 205
Query: 177 GCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIIS 236
G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+LIA
Sbjct: 206 GILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAV 265
Query: 237 LLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDHTDYQTPQ 280
LAA+P+++ PK +P+ S +R+ +S S++S D
Sbjct: 266 ALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQI 325
Query: 281 GENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSS 340
N +++ + F L +P++ L + + + GM T+ PK++E+Q+ ++S
Sbjct: 326 APNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITAS 385
Query: 341 RANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCEN 400
AN +IG ++ P+V +GI GG+++K+ + G L L + L LF +GC +
Sbjct: 386 YANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSS 445
Query: 401 SDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT 459
+AG+T + ++ L C C C + P+C + Y++ C AGC +
Sbjct: 446 HQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSS 500
Query: 460 ----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYT 515
+ + NC+CV GN + G C D+ C + + FL++ + S
Sbjct: 501 WVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSAL 552
Query: 516 LSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRC 575
L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+ W C
Sbjct: 553 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-C 611
Query: 576 GSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617
G R CR Y++++ R+ ++GL T S++ VL +L++
Sbjct: 612 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 653
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 300 bits (767), Expect = 4e-81
Identities = 186/642 (28%), Positives = 315/642 (49%), Gaps = 80/642 (12%)
Query: 42 LKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+K+F+ S + A+ + GYLKS+I+ +E+RF + S G++ E+GN +I FVSY
Sbjct: 48 IKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSY 107
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSN-STLSISPCLLESSS 160
FG+++HRP++IG G +++ + LL+ +P F E Y+Y+ SP S CL +S+
Sbjct: 108 FGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSA 167
Query: 161 QLP------------------VSVM--------------------------EKSKSKISN 176
V +M S S +
Sbjct: 168 PASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYL 227
Query: 177 GCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIIS 236
G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+LIA
Sbjct: 228 GILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAV 287
Query: 237 LLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDHTDYQTPQ 280
LAA+P+++ PK +P+ S +R+ +S S++S D
Sbjct: 288 ALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQI 347
Query: 281 GENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSS 340
N +++ + F L +P++ L + + + GM T+ PK++E+Q+ ++S
Sbjct: 348 APNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITAS 407
Query: 341 RANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCEN 400
AN +IG ++ P+V +GI GG+++K+ + G L L + L LF +GC +
Sbjct: 408 YANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSS 467
Query: 401 SDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSACLAGCQT 459
+AG+T + ++ L C C C + P+C + Y++ C AGC +
Sbjct: 468 HQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSS 522
Query: 460 ----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYT 515
+ + NC+CV GN + G C D+ C + + FL++ + S
Sbjct: 523 WVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLLVSLGSAL 574
Query: 516 LSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRC 575
L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+ W C
Sbjct: 575 ACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALS-C 633
Query: 576 GSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617
G R CR Y++++ R+ ++GL T S++ VL +L++
Sbjct: 634 GRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 675
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 288 bits (738), Expect = 9e-78
Identities = 164/592 (27%), Positives = 298/592 (50%), Gaps = 54/592 (9%)
Query: 58 LAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCV 117
+ G + +I+ +E+R+++ SSL G+I S++I L+ FVS+FG + H+P+ +
Sbjct: 121 VVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAF 180
Query: 118 IMGVGTLLIAMPQFFMEQYKY-ERYSPSSNSTLSISPCLLESSS---------------- 160
++G+G L+ ++PQFF +YK + + +T + + C +SS
Sbjct: 181 MIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLG 240
Query: 161 -------QLPVSVMEKS----KSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNL 209
L + ++ S KS + G ++I+GP G++LG +Y+D+
Sbjct: 241 AGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMG-- 298
Query: 210 DHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFI 269
+ +T DP+W+GAWW+G+L++ I + +PF PK LP + + +S
Sbjct: 299 ESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQA----- 353
Query: 270 IDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPK 329
+Q+ + K + +DF +LKNL N V+ + +++ + G T+ PK
Sbjct: 354 ------HQSNSNADVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPK 407
Query: 330 YIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLL 389
+IE Q+G +SS A + G + IP ALG GG ++ KFR++ K L +S L
Sbjct: 408 FIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTL 467
Query: 390 FLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITY 449
CEN AG++ SY GT + L + CN+ C CS + + P+CG+ G+ Y
Sbjct: 468 SFVFMYAKCENEPFAGVSESYNGTGELGN----LIAPCNANCNCSRSYYYPVCGD-GVQY 522
Query: 450 VSACLAGCQTSNRSGKNIIFYNCTCVG-----IAASKSGNSSGIVGRCQKDNGCPQMFLY 504
S C AGC K ++YNC+C+ + +++ G+C+ C ++ ++
Sbjct: 523 FSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKCETH--CAKLPIF 580
Query: 505 FLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLID 564
+ ++ +T + G P + +LRC+ + +S ALGI + +R+L IP P+ FG ID
Sbjct: 581 LCIFFIVIIFTF-MAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTID 639
Query: 565 TSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILK 616
++C+ W CG +G+C +YD+ H+ + ++V +++ + +F+ K
Sbjct: 640 STCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYK 691
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 283 bits (724), Expect = 4e-76
Identities = 185/648 (28%), Positives = 299/648 (46%), Gaps = 88/648 (13%)
Query: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
Query: 153 P--------------------C--LLESSSQLPVSVM---------EKSKSKISNGCVQT 181
P C +L P+ + +K S + +
Sbjct: 248 PPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYV 307
Query: 182 VAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAV 241
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 308 MGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIF 363
Query: 242 PFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD-------YQTPQGENAKIMEMA---- 290
P + PK LP ++ +K KF +D +D + + K+ M
Sbjct: 364 PMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKD 417
Query: 291 -RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLI 349
RD + + N + + T + + +T+ PK+IE Q+G +S A+ G+I
Sbjct: 418 VRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVI 477
Query: 350 NIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVS 409
+P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE+ ++ G+ +
Sbjct: 478 IVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIP 537
Query: 410 YQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIF 469
Y ++ R L CN C C ++EP+CG +GITY + CLAGC S I
Sbjct: 538 YTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRN 597
Query: 470 Y-NCTCVG--------------------IAASKSGNSSGIVGRCQKDNGCPQMFLYFLVI 508
Y CTCV + + N + G+C++ C + FLV
Sbjct: 598 YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C-NTLIPFLVF 654
Query: 509 SVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCL 568
I ++ + I+ LR ++ + + FALG+ + +R LA IP P+YFG +IDT+C+
Sbjct: 655 LFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCM 714
Query: 569 KWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILK 616
W + CG +GSC Y+ FR +Y GL L V + + +K
Sbjct: 715 LWQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 761
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 281 bits (719), Expect = 1e-75
Identities = 181/602 (30%), Positives = 290/602 (48%), Gaps = 49/602 (8%)
Query: 45 FLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGA 104
FLCA +F+ G++ + IT +ERR+D+ S G+I S++I L +TFVSYFG
Sbjct: 108 FLCAAAFLQ--GMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCLTFVSYFGG 165
Query: 105 KLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYE-----RYSPSS------NSTLSISP 153
H+P+ +G G ++MG G+L+ A+P F +Y+ E R P++ +ST +S
Sbjct: 166 SGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELDAGVRTCPANPGAVCADSTSGLSR 225
Query: 154 C--------LLESSSQLPVSVM---------EKSKSKISNGCVQTVAIIGPIFGFLLGSL 196
L P+ + + S S + T AI+GP G+L+G
Sbjct: 226 YQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVYIAIFYTAAILGPAAGYLIGGA 285
Query: 197 CAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSR 256
+Y ++G +T + P WVGAWW+G+L +G + AVP P+ LP SQ
Sbjct: 286 LLNIYTEMG----RRTELTTESPLWVGAWWVGFLGSGAAAFFTAVPILGYPRQLPGSQRY 341
Query: 257 EDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQ 316
++ + D + N + RD S+ L NP + L +
Sbjct: 342 AVMRAAE------MHQLKDSSRGEASNPDFGKTIRDLPLSIWLLLKNPTFILLCLAGATE 395
Query: 317 FNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAA 376
+ GM T+ PK++E Q+ S+S A + G + +PA G F GG + K R+
Sbjct: 396 ATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLRLRGSAVI 455
Query: 377 KLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSET 436
K L +V LL + +F+L C + +AG+T SY G+ H L + CN+ C C
Sbjct: 456 KFCLFCTVVS-LLGILVFSLHCPSVPMAGVTASYGGSLLPEGHLN-LTAPCNAACSCQPE 513
Query: 437 KWEPMCGENGITYVSACLAGCQTSNRSGKN--IIFYNCTCVGIAASKSGNSSGIVGRCQK 494
+ P+CG +G+ Y S C AGC + + + ++ +C+C+ S SG G+C
Sbjct: 514 HYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRDCSCIPQNLS-SGFGHATAGKCTS 572
Query: 495 DNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIP 554
C + L + I V+ +T L IP LRC++ +SFALGI + +R+L GIP
Sbjct: 573 T--CQRKPLLLVFIFVVIFFTF-LSSIPALTATLRCVRDPQRSFALGIQWIVVRILGGIP 629
Query: 555 APVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFI 614
P+ FG +ID +CL W +CG +GSC +Y ++ L + ++ + +L F+
Sbjct: 630 GPIAFGWVIDKACLLWQ-DQCGQQGSCLVYQNSAMSRYILIMGLLYKVLGVLFFAIACFL 688
Query: 615 LK 616
K
Sbjct: 689 YK 690
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 248 bits (633), Expect = 1e-65
Identities = 177/636 (27%), Positives = 280/636 (44%), Gaps = 119/636 (18%)
Query: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
Query: 153 P--------------------C--LLESSSQLPVSVM---------EKSKSKISNGCVQT 181
P C +L P+ + +K S + +
Sbjct: 248 PPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYV 307
Query: 182 VAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAV 241
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 308 MGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIF 363
Query: 242 PFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLF 301
P + PK LP ++ +K KF +D +D + E + E A + S+ F
Sbjct: 364 PMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLK-EKSNNSEQADKKVSSMG--F 414
Query: 302 GNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSG 361
G V G+I +P+ +GI G
Sbjct: 415 GKDVR----------------------------------------GVIIVPSAGVGIVLG 434
Query: 362 GIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHER 421
G ++KK ++ +AKL + S L F +LF +GCE+ ++ G+ + Y ++ R
Sbjct: 435 GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHR 494
Query: 422 ALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFY-NCTCVG---- 476
L CN C C ++EP+CG +GITY + CLAGC S I Y CTCV
Sbjct: 495 NLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQV 554
Query: 477 ----------------IAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGG 520
+ + N + G+C++ C + FLV I ++ +
Sbjct: 555 ITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C-NTLIPFLVFLFIVTFITACAQ 611
Query: 521 IPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGS 580
I+ LR ++ + + FALG+ + +R LA IP P+YFG +IDT+C+ W + CG +GS
Sbjct: 612 PSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGS 670
Query: 581 CRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILK 616
C Y+ FR +Y GL L V + + +K
Sbjct: 671 CWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 706
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 233 bits (593), Expect = 6e-61
Identities = 140/469 (29%), Positives = 238/469 (50%), Gaps = 35/469 (7%)
Query: 170 SKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGY 229
S S + G + V ++GP F LGSL +LYVDI + I++T KDP+WVGAWWLG+
Sbjct: 77 SNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGF 136
Query: 230 LIAGIISLLAAVPFWYLPKSLPR----------------SQSREDSNSSSEKSKFIIDDH 273
LIA LAA+P+++ PK +P+ S +R+ +S S++S
Sbjct: 137 LIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKK 196
Query: 274 TDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQ 333
D N +++ + F L +P++ L + + + GM T+ PK++E+
Sbjct: 197 QDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLER 256
Query: 334 QYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSL 393
Q+ ++S AN +IG ++ P+V +GI GG+++K+ + G L L + L L
Sbjct: 257 QFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPL 316
Query: 394 FALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCG-ENGITYVSA 452
F +GC + +AG+T + ++ L C C C + P+C + Y++
Sbjct: 317 FFIGCSSHQIAGIT-----HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITP 371
Query: 453 CLAGCQT----SNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVI 508
C AGC + + + NC+CV GN + G C D+ C + + FL++
Sbjct: 372 CHAGCSSWVVQDALDNSQVFYTNCSCV-----VEGNPV-LAGSC--DSTCSHLVVPFLLL 423
Query: 509 SVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCL 568
+ S L P ++L+LR +K + K+ A+GI + +R+LA +P+PV G IDT+C+
Sbjct: 424 VSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCV 483
Query: 569 KWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKK 617
W CG R CR Y++++ R+ ++GL T S++ VL +L++
Sbjct: 484 HWALS-CGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQ 531
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 223 bits (569), Expect = 3e-58
Identities = 142/487 (29%), Positives = 227/487 (46%), Gaps = 64/487 (13%)
Query: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
Query: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
Query: 153 P--------------------C--LLESSSQLPVSVM---------EKSKSKISNGCVQT 181
P C +L P+ + +K S + +
Sbjct: 248 PPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYV 307
Query: 182 VAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAV 241
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 308 MGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIF 363
Query: 242 PFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD-------YQTPQGENAKIMEMA---- 290
P + PK LP ++ +K KF +D +D + + K+ M
Sbjct: 364 PMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKD 417
Query: 291 -RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLI 349
RD + + N + + T + + +T+ PK+IE Q+G +S A+ G+I
Sbjct: 418 VRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVI 477
Query: 350 NIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVS 409
+P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE+ ++ G+ +
Sbjct: 478 IVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIP 537
Query: 410 YQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIF 469
Y ++ R L CN C C ++EP+CG +GITY + CLAGC S I
Sbjct: 538 YTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRN 597
Query: 470 Y-NCTCV 475
Y CTCV
Sbjct: 598 YTECTCV 604
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 194 bits (494), Expect = 2e-49
Identities = 138/615 (22%), Positives = 270/615 (43%), Gaps = 57/615 (9%)
Query: 38 CCGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVIT 97
CC ++ F+ + + + G + +I ++ + + + ++ S++I + LV
Sbjct: 101 CCNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAI 160
Query: 98 FVSYFGAKLHRPKIIG--AGCVIMGVGTLLIAMPQF-------------FMEQYKYERYS 142
F++++G R K+I A ++G+G+LL A P E+ K
Sbjct: 161 FIAFYG---DRKKVIWFVASSFLIGLGSLLCAFPSINEENKQSKVGIEDICEEIKVVSGC 217
Query: 143 PSSNSTLS---ISPCLLESSSQ---------LPVSVMEKS----KSKISNGCVQTVAIIG 186
SS + +S +L + Q L ++ ++++ + I G + ++IG
Sbjct: 218 QSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIAECTSMIG 277
Query: 187 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 246
G++LG+ K V + + T+ P+W+ WW+ +L A +++ +P
Sbjct: 278 YALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLIPLSCF 335
Query: 247 PKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVY 306
P ++P S + + K D ++ K+ +D +L L NPV
Sbjct: 336 PNNMPGSTRIK---ARKRKQLHFFDSRL-------KDLKLGTNIKDLCAALWILMKNPVL 385
Query: 307 FLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMK 366
+ ++ + G + P Y+E Q+ + + A + GL+ IP ALG GG+++
Sbjct: 386 ICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVS 445
Query: 367 KFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSD 426
+S + + +SV +L + + + C AG+ Y GT + L +
Sbjct: 446 TLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKLGN----LTAP 501
Query: 427 CNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVG---IAASKSG 483
CN +C+CS + + +CG + I Y S C AGC S + ++YNC+C+ I A G
Sbjct: 502 CNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQKKMYYNCSCIKEGLITADAEG 561
Query: 484 NS-SGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGI 542
+ G+C +F+ F+ ++I S G+P + + R + +L+S ALG+
Sbjct: 562 DFIDARPGKCDAKCYKLPLFIAFIFSTLIFS---GFSGVPIVLAMTRVVPDKLRSLALGV 618
Query: 543 YTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGT 602
+ +R+ IP P F + +TSC+ +CG G C +Y+ + +G+ +
Sbjct: 619 SYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMAFLLVGICFLCKL 678
Query: 603 VSILLSIAVLFILKK 617
+I+ + FI K+
Sbjct: 679 CTIIFTTIAFFIYKR 693
>gi|11863156 RECK protein precursor [Homo sapiens]
Length = 971
Score = 36.6 bits (83), Expect = 0.076
Identities = 14/27 (51%), Positives = 21/27 (77%), Gaps = 1/27 (3%)
Query: 431 CKCSETKWEPMCGENGITYVSACLAGC 457
C C++ ++ P+CG+NG TY SAC+A C
Sbjct: 633 CNCAD-QFVPVCGQNGRTYPSACIARC 658
Score = 33.5 bits (75), Expect = 0.64
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 13/77 (16%)
Query: 406 LTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGK 465
L YQ K +SY C C+ +E P+CG NG TY S C A S+R
Sbjct: 734 LCTLYQRGKSLSYK-----GPCQPFCRATE----PVCGHNGETYSSVCAA---YSDRVAV 781
Query: 466 NIIFYNCTCVGIAASKS 482
+ + +C VG+ + S
Sbjct: 782 D-YYGDCQAVGVLSEHS 797
>gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Homo
sapiens]
Length = 856
Score = 32.3 bits (72), Expect = 1.4
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 4/68 (5%)
Query: 341 RANFVIGLINIP-AVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLF---AL 396
+ + ++G+I++ V LGIF+ KKF I + +L +FGYL+F+ +
Sbjct: 553 KMSVILGIIHMTFGVILGIFNHLHFRKKFNIYLVSIPELLFMLCIFGYLIFMIFYKWLVF 612
Query: 397 GCENSDVA 404
E S VA
Sbjct: 613 SAETSRVA 620
>gi|9945322 solute carrier family 17, member 7 [Homo sapiens]
Length = 560
Score = 32.0 bits (71), Expect = 1.9
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 243 FWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLFG 302
FWYL L +S S SE+ + I+D GE+AK+M F + F
Sbjct: 247 FWYLFWLLVSYESPALHPSISEEERKYIEDAI------GESAKLMNPLTKFSTPWRRFFT 300
Query: 303 NPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGL 348
+ + + + + + + ++ +P Y E+ +G S+ V L
Sbjct: 301 SMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSAL 346
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 30.8 bits (68), Expect = 4.2
Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 427 CNSRCKCSETKWEPMCGENGITYVSACL---AGCQTSNR 462
C CS+T + P+C +G +Y +AC A CQ +
Sbjct: 180 CVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEK 218
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 30.4 bits (67), Expect = 5.5
Identities = 11/26 (42%), Positives = 19/26 (73%), Gaps = 3/26 (11%)
Query: 431 CKCSE---TKWEPMCGENGITYVSAC 453
C+C + + ++P+CG +G+TY SAC
Sbjct: 488 CECLQACSSLYDPVCGSDGVTYGSAC 513
>gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo
sapiens]
Length = 918
Score = 30.4 bits (67), Expect = 5.5
Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 18/144 (12%)
Query: 240 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGE----NAKIMEMAR---D 292
A+ F K PR RED NS +++ D+ ++Q + + K++E+A
Sbjct: 187 ALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDATKHKLIEIANYVDK 246
Query: 293 FLPSLK---NLFGNPVY-FLYLC-TSTVQFNSLFGMVTYKPKYIEQQYGQSS------SR 341
F SL L G V+ +C S +++L+ ++++ K + Q+Y ++ S
Sbjct: 247 FYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRRKLLAQKYHDNAQLITGMSF 306
Query: 342 ANFVIGLINIPAVALGIFSGGIVM 365
IGL + A+ SGG+ M
Sbjct: 307 HGTTIGLAPLMAMCSVYQSGGVNM 330
>gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor
[Homo sapiens]
Length = 1338
Score = 30.0 bits (66), Expect = 7.1
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 442 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 501
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 502 FLYFLVISVI 511
+Y + +I
Sbjct: 137 EMYSEIPEII 146
>gi|229892220 fms-related tyrosine kinase 1 isoform 2 precursor
[Homo sapiens]
Length = 687
Score = 30.0 bits (66), Expect = 7.1
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 442 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 501
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 502 FLYFLVISVI 511
+Y + +I
Sbjct: 137 EMYSEIPEII 146
>gi|229892302 fms-related tyrosine kinase 1 isoform 4 precursor
[Homo sapiens]
Length = 541
Score = 30.0 bits (66), Expect = 7.1
Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 442 CGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQM 501
CG NG + S +N +G FY+C + + SK + + D G P +
Sbjct: 81 CGRNGKQFCSTLTLNTAQANHTG----FYSCKYLAVPTSKKKETESAIYIFISDTGRPFV 136
Query: 502 FLYFLVISVI 511
+Y + +I
Sbjct: 137 EMYSEIPEII 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,850,246
Number of Sequences: 37866
Number of extensions: 1032105
Number of successful extensions: 2508
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2391
Number of HSP's gapped (non-prelim): 66
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.