Search of human proteins with 221139904

Search of human proteins with 221139904

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221139904 TBC1 domain family, member 7 isoform a [Homo
sapiens]
         (293 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221139907 TBC1 domain family, member 7 isoform a [Homo sapiens]    595   e-170
gi|221139904 TBC1 domain family, member 7 isoform a [Homo sapiens]    595   e-170
gi|7706041 TBC1 domain family, member 7 isoform a [Homo sapiens]      595   e-170
gi|221139909 TBC1 domain family, member 7 isoform b [Homo sapiens]    525   e-149
gi|34147456 TBC domain-containing protein kinase-like [Homo sapi...    40   0.002
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             39   0.005
gi|114688046 TBC1 domain family, member 4 [Homo sapiens]               39   0.007
gi|157388983 TBC1 domain family, member 19 [Homo sapiens]              35   0.060
gi|239755853 PREDICTED: TBC1 domain family, member 30 [Homo sapi...    35   0.078
gi|239750365 PREDICTED: TBC1 domain family, member 30 [Homo sapi...    35   0.078
gi|239744669 PREDICTED: TBC1 domain family, member 30 [Homo sapi...    35   0.078
gi|40068063 TBC1 domain family, member 22B [Homo sapiens]              35   0.078
gi|38348348 TBC1 domain family, member 10C [Homo sapiens]              35   0.078
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]               35   0.10 
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]             35   0.10 
gi|217035118 TBC1 domain family, member 23 [Homo sapiens]              35   0.10 
gi|229577000 ecotropic viral integration site 5-like isoform 1 [...    33   0.23 
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H...    33   0.23 
gi|13994322 TBC1 domain family, member 10A [Homo sapiens]              33   0.23 
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member...    33   0.23 
gi|190014603 TBC1 domain family, member 13 [Homo sapiens]              33   0.30 
gi|33563376 TBC1 domain family, member 16 [Homo sapiens]               30   1.9  
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]     30   2.5  
gi|62955805 vang-like 2 [Homo sapiens]                                 29   4.3  
gi|21536371 telomerase-associated protein 1 [Homo sapiens]             29   5.6  
gi|7662108 Cdc42 guanine exchange factor 9 [Homo sapiens]              29   5.6  
gi|29648315 small G protein signaling modulator 3 [Homo sapiens]       29   5.6  
gi|222352143 TBC1 domain family, member 2 [Homo sapiens]               28   7.3  

>gi|221139907 TBC1 domain family, member 7 isoform a [Homo sapiens]
          Length = 293

 Score =  595 bits (1535), Expect = e-170
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW 60
           MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW
Sbjct: 1   MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW 60

Query: 61  KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP 120
           KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP
Sbjct: 61  KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP 120

Query: 121 RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY 180
           RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY
Sbjct: 121 RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY 180

Query: 181 LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV 240
           LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV
Sbjct: 181 LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV 240

Query: 241 EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS 293
           EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS
Sbjct: 241 EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS 293


>gi|221139904 TBC1 domain family, member 7 isoform a [Homo sapiens]
          Length = 293

 Score =  595 bits (1535), Expect = e-170
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW 60
           MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW
Sbjct: 1   MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW 60

Query: 61  KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP 120
           KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP
Sbjct: 61  KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP 120

Query: 121 RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY 180
           RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY
Sbjct: 121 RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY 180

Query: 181 LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV 240
           LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV
Sbjct: 181 LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV 240

Query: 241 EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS 293
           EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS
Sbjct: 241 EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS 293


>gi|7706041 TBC1 domain family, member 7 isoform a [Homo sapiens]
          Length = 293

 Score =  595 bits (1535), Expect = e-170
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW 60
           MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW
Sbjct: 1   MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW 60

Query: 61  KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP 120
           KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP
Sbjct: 61  KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP 120

Query: 121 RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY 180
           RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY
Sbjct: 121 RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY 180

Query: 181 LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV 240
           LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV
Sbjct: 181 LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV 240

Query: 241 EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS 293
           EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS
Sbjct: 241 EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS 293


>gi|221139909 TBC1 domain family, member 7 isoform b [Homo sapiens]
          Length = 266

 Score =  525 bits (1353), Expect = e-149
 Identities = 266/293 (90%), Positives = 266/293 (90%), Gaps = 27/293 (9%)

Query: 1   MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVW 60
           MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRL                       
Sbjct: 1   MTEDSQRNFRSVYYEKVGFRGVEEKKSLEILLKDDRL----------------------- 37

Query: 61  KVLLGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP 120
               GILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP
Sbjct: 38  ----GILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEVYLRMYQLESGKLP 93

Query: 121 RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY 180
           RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY
Sbjct: 94  RSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQY 153

Query: 181 LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV 240
           LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV
Sbjct: 154 LNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAV 213

Query: 241 EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS 293
           EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS
Sbjct: 214 EILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTPVHSS 266


>gi|34147456 TBC domain-containing protein kinase-like [Homo
           sapiens]
          Length = 830

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 4/113 (3%)

Query: 177 FEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILV 236
           F Q +   D  L  HL      P L    WF   F    P   +  +WD ++ G+     
Sbjct: 534 FSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPF 593

Query: 237 FVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCGTP 289
            + V IL   + +++A    E I  F  ++P+   +  V ++I+L+   C TP
Sbjct: 594 CIGVAILQQLRDRLLANGFNECILLF-SDLPEIDIERCVRESINLF---CWTP 642


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 5/96 (5%)

Query: 191 HLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKV 250
           HLR     P L    WF   FA  LP +S+ RVWD       KI+  VA+ +L      V
Sbjct: 508 HLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSV 567

Query: 251 MALNSAEKITKFLE---NIPQD--SSDAIVSKAIDL 281
             L S + + + +E   N+PQ     D +V +  +L
Sbjct: 568 EKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNL 603


>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
          Length = 1298

 Score = 38.5 bits (88), Expect = 0.007
 Identities = 25/92 (27%), Positives = 42/92 (45%)

Query: 188  LLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFK 247
            L  HL     +P L    WF   FA       + RV+D +     +++  VA+ +L + +
Sbjct: 1069 LYNHLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLSSQE 1128

Query: 248  IKVMALNSAEKITKFLENIPQDSSDAIVSKAI 279
              +M   S E I +FL+N   D + + + K I
Sbjct: 1129 TLIMECESFENIVEFLKNTLPDMNTSEMEKII 1160


>gi|157388983 TBC1 domain family, member 19 [Homo sapiens]
          Length = 526

 Score = 35.4 bits (80), Expect = 0.060
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%)

Query: 177 FEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVS-GSCKIL 235
           FE  L     +L  HLR   A P      W  R F+G L    L  +WD+++   S +IL
Sbjct: 418 FETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEIL 477

Query: 236 VFVAVEILLTFKIKVMALNS 255
             +A  +     + +M + S
Sbjct: 478 AVLAAAVFAFRAVNLMEVTS 497


>gi|239755853 PREDICTED: TBC1 domain family, member 30 [Homo
           sapiens]
          Length = 761

 Score = 35.0 bits (79), Expect = 0.078
 Identities = 15/64 (23%), Positives = 32/64 (50%)

Query: 206 WFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLEN 265
           WF   FA CLP  ++ ++WD V     +I++ V++ I      ++    +A++    +  
Sbjct: 269 WFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGR 328

Query: 266 IPQD 269
           + Q+
Sbjct: 329 LTQE 332


>gi|239750365 PREDICTED: TBC1 domain family, member 30 [Homo
           sapiens]
          Length = 761

 Score = 35.0 bits (79), Expect = 0.078
 Identities = 15/64 (23%), Positives = 32/64 (50%)

Query: 206 WFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLEN 265
           WF   FA CLP  ++ ++WD V     +I++ V++ I      ++    +A++    +  
Sbjct: 269 WFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGR 328

Query: 266 IPQD 269
           + Q+
Sbjct: 329 LTQE 332


>gi|239744669 PREDICTED: TBC1 domain family, member 30 [Homo
           sapiens]
          Length = 761

 Score = 35.0 bits (79), Expect = 0.078
 Identities = 15/64 (23%), Positives = 32/64 (50%)

Query: 206 WFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLEN 265
           WF   FA CLP  ++ ++WD V     +I++ V++ I      ++    +A++    +  
Sbjct: 269 WFLTLFATCLPNQTVLKIWDSVFFEGSEIILRVSLAIWAKLGEQIECCETADEFYSTMGR 328

Query: 266 IPQD 269
           + Q+
Sbjct: 329 LTQE 332


>gi|40068063 TBC1 domain family, member 22B [Homo sapiens]
          Length = 505

 Score = 35.0 bits (79), Expect = 0.078
 Identities = 57/296 (19%), Positives = 107/296 (36%), Gaps = 52/296 (17%)

Query: 22  VEEKKSLEI---LLKDDRLDTEKLCTFSQRFP-LPSMYRALVWKVLLGILPPHHESHAKV 77
           V EK  LE    LL     D ++L   S  +P +P   R + W++L G LP + E     
Sbjct: 180 VREKTRLEKFRQLLSSQNTDLDELRKCS--WPGVPREVRPITWRLLSGYLPANTERRKLT 237

Query: 78  MMYRKEQYLDVL----------HALKVVRFVSDATPQA-------------EVYLRMYQL 114
           +  ++E+Y   +          H     R +    P+              E++ R+  +
Sbjct: 238 LQRKREEYFGFIEQYYDSRNEEHHQDTYRQIHIDIPRTNPLIPLFQQPLVQEIFERILFI 297

Query: 115 ESGKLPRS-----------PSFP------LEPDDEVFLAIAKAMEEMVEDSVDCYWITRR 157
            + + P S           P F       +E D E F     + + +     D +W   +
Sbjct: 298 WAIRHPASGYVQGINDLVTPFFVVFLSEYVEEDVENFDVTNLSQDMLRSIEADSFWCMSK 357

Query: 158 FVNQLNTKYRDSLPQLP---KAFEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGC 214
            ++ +   Y  + P +    KA E+ ++  D ++  H R            W        
Sbjct: 358 LLDGIQDNYTFAQPGIQKKVKALEELVSRIDEQVHNHFRRYEVEYLQFAFRWMNNLLMRE 417

Query: 215 LPESSLQRVWDKVVS---GSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIP 267
           LP     R+WD   S   G     ++V    L+ ++ +++     + +   L+N+P
Sbjct: 418 LPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLIKWRKEILDEEDFQGLLMLLQNLP 473


>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
          Length = 446

 Score = 35.0 bits (79), Expect = 0.078
 Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 191 HLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKV 250
           HL+     P L    WF   FA  LP  ++ RVWD  +S   ++L  V + ++       
Sbjct: 240 HLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGARVLFRVGLTLVR------ 293

Query: 251 MALNSAEK 258
           +AL +AE+
Sbjct: 294 LALGTAEQ 301


>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
          Length = 828

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 24/92 (26%), Positives = 39/92 (42%)

Query: 178 EQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVF 237
           E+ LN    +L  HL             WF +CF    P +   R+WD  +    ++L  
Sbjct: 239 EKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTA 298

Query: 238 VAVEILLTFKIKVMALNSAEKITKFLENIPQD 269
           ++  IL   K  +M L+  E +  F E + +D
Sbjct: 299 MSYTILKLHKKHLMKLSMEELVEFFQETLAKD 330


>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
          Length = 845

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 24/92 (26%), Positives = 39/92 (42%)

Query: 178 EQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVF 237
           E+ LN    +L  HL             WF +CF    P +   R+WD  +    ++L  
Sbjct: 256 EKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTA 315

Query: 238 VAVEILLTFKIKVMALNSAEKITKFLENIPQD 269
           ++  IL   K  +M L+  E +  F E + +D
Sbjct: 316 MSYTILKLHKKHLMKLSMEELVEFFQETLAKD 347


>gi|217035118 TBC1 domain family, member 23 [Homo sapiens]
          Length = 684

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 56/282 (19%), Positives = 96/282 (34%), Gaps = 37/282 (13%)

Query: 25  KKSLEILLKDDRLDTEKLCTFSQRFPLPSMYRALVWKVLLGI---------------LPP 69
           +K LE  L+    D E L    Q  PLP+  RA VWK+ L +               LP 
Sbjct: 19  EKDLEEALEAGGCDLETLRNIIQGRPLPADLRAKVWKIALNVAGKGDSLASWDGILDLPE 78

Query: 70  HHESHAKVMMYRKEQYLDVLHA--LKVVRFVSDATPQAEVYLRMYQLESGKLPRSPSFPL 127
            +  H   +     Q++D L     K    + D       Y +     S  +  S S   
Sbjct: 79  QNTIHKDCL-----QFIDQLSVPEEKAAELLLDIESVITFYCK-----SRNIKYSTSLS- 127

Query: 128 EPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGR 187
                 ++ + K +  +     D Y      +N+   +      +    F   +   +  
Sbjct: 128 ------WIHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFHLFRLLIQYHEPE 181

Query: 188 LLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFK 247
           L ++L      P      W    FA        Q +WD  +  +    ++  + I+L   
Sbjct: 182 LCSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYLQQADPFFIYFLMLIILVNA 241

Query: 248 IKVMAL---NSAEKITKFLENIPQDSSDAIVSKAIDLWHKHC 286
            +V+     +S E++ KFLEN P   +   +     L   +C
Sbjct: 242 KEVILTQESDSKEEVIKFLENTPSSLNIEDIEDLFSLAQYYC 283


>gi|229577000 ecotropic viral integration site 5-like isoform 1
           [Homo sapiens]
          Length = 805

 Score = 33.5 bits (75), Expect = 0.23
 Identities = 53/243 (21%), Positives = 89/243 (36%), Gaps = 32/243 (13%)

Query: 40  EKLCTFSQRFPLPSMYRALVWKVLLGILPPHHESHAKVMMYRKEQYLDVLHALK-----V 94
           EKL     R  +P  +RA+VW++L               M  K QY ++L         +
Sbjct: 105 EKLLKELIRKGIPHHFRAIVWQLLCSATD----------MPVKNQYSELLKMSSPCEKLI 154

Query: 95  VRFVSDATPQAEVYLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKA------MEEMVEDS 148
            R ++   P+ E +     L    L          D EV      A      + +M E+ 
Sbjct: 155 RRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEE 214

Query: 149 VDCYWITRRFVNQLNTKYRDSLPQLPKA---FEQYLNLEDGRLLTHLRMCSAAPKLPYDL 205
             C ++      +L   ++ S+ +L      FE  L  +   L TH R  S    +    
Sbjct: 215 AFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASS 274

Query: 206 WFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLEN 265
           WF   F    P     RV+D        I ++  +EI+    + ++ +N AE +   +E 
Sbjct: 275 WFLTLFLTTFPLPVATRVFD--------IFMYEGLEIVFRVGLALLQVNQAELMQLDMEG 326

Query: 266 IPQ 268
           + Q
Sbjct: 327 MSQ 329


>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
           sapiens]
          Length = 794

 Score = 33.5 bits (75), Expect = 0.23
 Identities = 53/243 (21%), Positives = 89/243 (36%), Gaps = 32/243 (13%)

Query: 40  EKLCTFSQRFPLPSMYRALVWKVLLGILPPHHESHAKVMMYRKEQYLDVLHALK-----V 94
           EKL     R  +P  +RA+VW++L               M  K QY ++L         +
Sbjct: 105 EKLLKELIRKGIPHHFRAIVWQLLCSATD----------MPVKNQYSELLKMSSPCEKLI 154

Query: 95  VRFVSDATPQAEVYLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKA------MEEMVEDS 148
            R ++   P+ E +     L    L          D EV      A      + +M E+ 
Sbjct: 155 RRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEE 214

Query: 149 VDCYWITRRFVNQLNTKYRDSLPQLPKA---FEQYLNLEDGRLLTHLRMCSAAPKLPYDL 205
             C ++      +L   ++ S+ +L      FE  L  +   L TH R  S    +    
Sbjct: 215 AFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASS 274

Query: 206 WFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLEN 265
           WF   F    P     RV+D        I ++  +EI+    + ++ +N AE +   +E 
Sbjct: 275 WFLTLFLTTFPLPVATRVFD--------IFMYEGLEIVFRVGLALLQVNQAELMQLDMEG 326

Query: 266 IPQ 268
           + Q
Sbjct: 327 MSQ 329


>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
          Length = 508

 Score = 33.5 bits (75), Expect = 0.23
 Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 6/69 (8%)

Query: 191 HLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKV 250
           HL      P L    WF   F+  LP SS+ RVWD       KI+  V + +L       
Sbjct: 259 HLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLL------K 312

Query: 251 MALNSAEKI 259
            AL S EK+
Sbjct: 313 HALGSPEKV 321


>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
            [Homo sapiens]
          Length = 1168

 Score = 33.5 bits (75), Expect = 0.23
 Identities = 20/78 (25%), Positives = 35/78 (44%)

Query: 188  LLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFK 247
            L  HL      P L    WF   FA   P   + RV+D +     +++  VA+ +L + K
Sbjct: 951  LYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHK 1010

Query: 248  IKVMALNSAEKITKFLEN 265
              ++   + E I  F+++
Sbjct: 1011 PLILQHENLETIVDFIKS 1028


>gi|190014603 TBC1 domain family, member 13 [Homo sapiens]
          Length = 400

 Score = 33.1 bits (74), Expect = 0.30
 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 6/121 (4%)

Query: 31  LLKDDRLDTEKLCTFS-QRFPLPSMYRALVWKVLLGILPPHHESHAKVMMYRKEQYLDVL 89
           +LK+  +  EKL   S    P     R L WK+LL  LP    S   ++  ++E Y   L
Sbjct: 15  VLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRELYAQFL 74

Query: 90  HALKVVRFVSDA---TPQAEVYLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVE 146
             + +   ++ A     + +V    + L     P S       D+EV L I K +  +  
Sbjct: 75  REMIIQPGIAKANMGVSREDVTFEDHPLNPN--PDSRWNTYFKDNEVLLQIDKDVRRLCP 132

Query: 147 D 147
           D
Sbjct: 133 D 133


>gi|33563376 TBC1 domain family, member 16 [Homo sapiens]
          Length = 767

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 12/97 (12%)

Query: 137 IAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCS 196
           +A  + E++++S D +W    FV  +      S P+     +Q L L +   LTH+R   
Sbjct: 537 VAPILAEVLDES-DTFWC---FVGLMQNTIFVSSPRDEDMEKQLLYLRELLRLTHVRFYQ 592

Query: 197 AAPKLPYD--------LWFKRCFAGCLPESSLQRVWD 225
               L  D         W   CF    PE+   R+W+
Sbjct: 593 HLVSLGEDGLQMLFCHRWLLLCFKREFPEAEALRIWE 629


>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
          Length = 336

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 16/65 (24%), Positives = 30/65 (46%)

Query: 206 WFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLEN 265
           WF   F   LP  ++ R+WD + +   KI+  VA+ ++   +  ++   S   I    + 
Sbjct: 233 WFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLIKQHQELILEATSVPDICDKFKQ 292

Query: 266 IPQDS 270
           I + S
Sbjct: 293 ITKGS 297


>gi|62955805 vang-like 2 [Homo sapiens]
          Length = 521

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 2/82 (2%)

Query: 101 ATPQAEVYLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVN 160
           A  +A  +++  Q E  K PR    P E    +F ++A+AM++ +  +    + T   + 
Sbjct: 362 AVEEAFTHIKRLQEEEQKNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESIL 421

Query: 161 QLNTKYRDSLPQLPKAF-EQYL 181
           Q + ++  +    PKAF E+YL
Sbjct: 422 Q-HLEFCITHDMTPKAFLERYL 442


>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
          Length = 2627

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 5/38 (13%)

Query: 41   KLCTF-----SQRFPLPSMYRALVWKVLLGILPPHHES 73
            +LCT+      +   LPS YR+LVW++   +LP   ES
Sbjct: 1217 RLCTYLRGQLKEPGALPSTYRSLVWELQQRLLPKSAES 1254


>gi|7662108 Cdc42 guanine exchange factor 9 [Homo sapiens]
          Length = 516

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 9/87 (10%)

Query: 150 DCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLL------THLRMCSAAPKLPY 203
           D Y     FV  L  +Y +  P L +    +L  +DG  +       HL  C    KL  
Sbjct: 154 DIYRFQMGFVRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKLMK 213

Query: 204 DLWFKRCFAGCLPESSLQRVWDKVVSG 230
           D  ++  F  C     LQ++ D  + G
Sbjct: 214 DSRYQHFFEAC---RLLQQMIDIAIDG 237


>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
          Length = 749

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 16/68 (23%), Positives = 30/68 (44%)

Query: 206 WFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLEN 265
           WF   FA  +    L R+WD       ++L  + + +L   + +++   ++  I   L +
Sbjct: 280 WFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSD 339

Query: 266 IPQDSSDA 273
           IP    DA
Sbjct: 340 IPSQMEDA 347


>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
          Length = 917

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 13/99 (13%)

Query: 127 LEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDG 186
           LE ++  F  +   +E ++     C  +T   V+Q             +  +  L+ +  
Sbjct: 726 LEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQ-------------RVLQDLLSEKLP 772

Query: 187 RLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWD 225
           RL+ HL        L    WF   FA  L  + L RVWD
Sbjct: 773 RLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWD 811


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,230,392
Number of Sequences: 37866
Number of extensions: 472996
Number of successful extensions: 1009
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 983
Number of HSP's gapped (non-prelim): 33
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.