Guide to the Human Genome
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Search of human proteins with 217272829

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|217272829 nuclear transcription factor Y, gamma isoform 3
[Homo sapiens]
         (334 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217272829 nuclear transcription factor Y, gamma isoform 3 [Ho...   651   0.0  
gi|11496978 nuclear transcription factor Y, gamma isoform 2 [Hom...   647   0.0  
gi|217272831 nuclear transcription factor Y, gamma isoform 1 [Ho...   635   0.0  
gi|217272835 nuclear transcription factor Y, gamma isoform 5 [Ho...   557   e-159
gi|217272833 nuclear transcription factor Y, gamma isoform 4 [Ho...   555   e-158
gi|38455394 DNA-directed DNA polymerase epsilon 4 [Homo sapiens]       64   1e-10
gi|8393116 chromatin accessibility complex 1 [Homo sapiens]            59   6e-09
gi|4505389 nuclear transcription factor Y, alpha isoform 1 [Homo...    59   8e-09
gi|18426973 DR1-associated protein 1 [Homo sapiens]                    56   5e-08
gi|221139761 zinc finger protein 853 [Homo sapiens]                    51   2e-06
gi|11496974 nuclear transcription factor Y, alpha isoform 2 [Hom...    50   4e-06
gi|44890059 involucrin [Homo sapiens]                                  48   1e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    46   4e-05
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   45   7e-05
gi|38788260 bromodomain PHD finger transcription factor isoform ...    45   7e-05
gi|38788274 bromodomain PHD finger transcription factor isoform ...    45   7e-05
gi|38570099 glutamine-rich 1 [Homo sapiens]                            45   9e-05
gi|38570097 glutamine-rich 1 [Homo sapiens]                            45   9e-05
gi|56549696 E1A binding protein p400 [Homo sapiens]                    44   3e-04
gi|110347429 mediator complex subunit 12 [Homo sapiens]                43   3e-04
gi|33286444 mastermind-like 2 [Homo sapiens]                           42   8e-04
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       42   8e-04
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       42   8e-04
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    42   0.001
gi|62865633 Sp3 transcription factor isoform 2 [Homo sapiens]          41   0.002
gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens]          41   0.002
gi|4506495 regulatory factor X3 isoform a [Homo sapiens]               40   0.004
gi|19743884 regulatory factor X3 isoform b [Homo sapiens]              40   0.004
gi|4758010 clock [Homo sapiens]                                        39   0.007
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   38   0.011

>gi|217272829 nuclear transcription factor Y, gamma isoform 3 [Homo
           sapiens]
          Length = 334

 Score =  651 bits (1680), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
           ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
Sbjct: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP
Sbjct: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQI 300
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQI
Sbjct: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQI 300

Query: 301 QQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 334
           QQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 301 QQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 334


>gi|11496978 nuclear transcription factor Y, gamma isoform 2 [Homo
           sapiens]
          Length = 335

 Score =  647 bits (1668), Expect = 0.0
 Identities = 334/335 (99%), Positives = 334/335 (99%), Gaps = 1/335 (0%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
           ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
Sbjct: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP
Sbjct: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG-QLYQ 299
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG QLYQ
Sbjct: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 300

Query: 300 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 334
           IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 301 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 335


>gi|217272831 nuclear transcription factor Y, gamma isoform 1 [Homo
           sapiens]
          Length = 354

 Score =  635 bits (1638), Expect = 0.0
 Identities = 334/354 (94%), Positives = 334/354 (94%), Gaps = 20/354 (5%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
           ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
Sbjct: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP
Sbjct: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQ-------------------QITQTE 281
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQ                   QITQTE
Sbjct: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQGQRNASQGKPRRCLKETLQITQTE 300

Query: 282 VQQGQQQFSQFTDG-QLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 334
           VQQGQQQFSQFTDG QLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 301 VQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 354


>gi|217272835 nuclear transcription factor Y, gamma isoform 5 [Homo
           sapiens]
          Length = 301

 Score =  557 bits (1436), Expect = e-159
 Identities = 299/335 (89%), Positives = 299/335 (89%), Gaps = 35/335 (10%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
           ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
Sbjct: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           A                         QPQ          GQTMQVMQQIITNTGEIQQIP
Sbjct: 181 A-------------------------QPQ---------QGQTMQVMQQIITNTGEIQQIP 206

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQ-LYQ 299
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQ LYQ
Sbjct: 207 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 266

Query: 300 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 334
           IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 267 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 301


>gi|217272833 nuclear transcription factor Y, gamma isoform 4 [Homo
           sapiens]
          Length = 297

 Score =  555 bits (1430), Expect = e-158
 Identities = 296/335 (88%), Positives = 296/335 (88%), Gaps = 39/335 (11%)

Query: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM 60
           MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVK 
Sbjct: 1   MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVK- 59

Query: 61  ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR 120
                                                RNDIAMAITKFDQFDFLIDIVPR
Sbjct: 60  -------------------------------------RNDIAMAITKFDQFDFLIDIVPR 82

Query: 121 DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 180
           DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
Sbjct: 83  DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII 142

Query: 181 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
           AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP
Sbjct: 143 AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 202

Query: 241 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG-QLYQ 299
           VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG QLYQ
Sbjct: 203 VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQ 262

Query: 300 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 334
           IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
Sbjct: 263 IQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD 297


>gi|38455394 DNA-directed DNA polymerase epsilon 4 [Homo sapiens]
          Length = 117

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 32/81 (39%), Positives = 49/81 (60%)

Query: 34  TVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKR 93
           +V   R+  LPLAR+K ++K D DV +   EA  + A+AA++F+  +   A+   +  KR
Sbjct: 32  SVPGARLSRLPLARVKALVKADPDVTLAGQEAIFILARAAELFVETIAKDAYCCAQQGKR 91

Query: 94  RTLQRNDIAMAITKFDQFDFL 114
           +TLQR D+  AI   D+F FL
Sbjct: 92  KTLQRRDLDNAIEAVDEFAFL 112


>gi|8393116 chromatin accessibility complex 1 [Homo sapiens]
          Length = 131

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 35/101 (34%), Positives = 56/101 (55%), Gaps = 8/101 (7%)

Query: 39  RVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQR 98
           R+  LPL+RI+ IMK   +V  I+ EA VL AKA ++F+  L   ++ H    +++ L  
Sbjct: 15  RLISLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQCLATYSYRHGSGKEKKVLTY 74

Query: 99  NDIAMAITKFDQFDFLIDIVPR--------DELKPPKRQEE 131
           +D+A    + + F FL DI+P+          LK  KR+E+
Sbjct: 75  SDLANTAQQSETFQFLADILPKKILASKYLKMLKEEKREED 115


>gi|4505389 nuclear transcription factor Y, alpha isoform 1 [Homo
           sapiens]
          Length = 347

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 56/174 (32%), Positives = 78/174 (44%), Gaps = 14/174 (8%)

Query: 150 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           QQ     VQ Q + Q  ++S   +Q  Q++  QP   Q +   +    GQ + +VQA P 
Sbjct: 26  QQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPI-MVQAVPG 84

Query: 210 GQAQQAQSGTGQTMQVMQQI-ITNTGEI-----QQIPVQLNAGQLQYIRLAQPVSGTQVV 263
           GQ Q          Q +QQI +   G+I     Q + VQ   GQ Q I + QP   T V 
Sbjct: 85  GQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQP--QTAVT 142

Query: 264 QGQIQT---LATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQP 314
            GQ QT   +A   QQ+ QT   +GQ    Q  +     +QQVT+P    +  P
Sbjct: 143 AGQTQTQQQIAVQGQQVAQT--AEGQTIVYQPVNADGTILQQVTVPVSGMITIP 194



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 54/194 (27%), Positives = 79/194 (40%), Gaps = 34/194 (17%)

Query: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
           T+ Q P +   QG QQ Q        IQ GQ +  Q QQGQT             QI+  
Sbjct: 89  TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ------------QIIIQ 135

Query: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI---PVQLNAGQLQYIRL---------A 254
           QPQ      Q+ T Q + V  Q +  T E Q I   PV  +   LQ + +         A
Sbjct: 136 QPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPA 195

Query: 255 QPVSGTQVVQGQIQTLATNAQQITQT--------EVQQGQQQFSQFTDGQLYQIQQVTMP 306
             ++G Q+VQ    T  T++ Q T T         V  G         G +  IQ++ +P
Sbjct: 196 ASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLP 255

Query: 307 AGQDL-AQPMFIQS 319
             + L  +P+++ +
Sbjct: 256 GAEMLEEEPLYVNA 269



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 40/130 (30%), Positives = 51/130 (39%), Gaps = 28/130 (21%)

Query: 226 MQQIITNTGE-IQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQI--QTLATNAQQITQTEV 282
           M+Q   N+    +QI VQ  AGQ+Q     Q   G   VQ Q   Q  + + QQ+   +V
Sbjct: 1   MEQYTANSNSSTEQIVVQ--AGQIQQ----QQQGGVTAVQLQTEAQVASASGQQVQTLQV 54

Query: 283 QQGQQQFSQFTDGQL------------------YQIQQVTMPAGQDLAQPMFIQSAN-QP 323
            QGQ    Q + GQL                    I QV +   Q L Q   +     Q 
Sbjct: 55  VQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQI 114

Query: 324 SDGQAPQVTG 333
             GQA QV G
Sbjct: 115 QGGQAVQVQG 124


>gi|18426973 DR1-associated protein 1 [Homo sapiens]
          Length = 205

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 27/75 (36%), Positives = 45/75 (60%)

Query: 44  PLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAM 103
           P ARIKKIM+ DE++  ++A  PV+ ++A ++F+  L  +A   T+    +T+  + +  
Sbjct: 13  PPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQ 72

Query: 104 AITKFDQFDFLIDIV 118
            I    QFDFL D+V
Sbjct: 73  CIELEQQFDFLKDLV 87


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 60/198 (30%), Positives = 80/198 (40%), Gaps = 21/198 (10%)

Query: 122 ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIA 181
           +L+  K Q    Q + P   + +      QP  VQ Q + Q QQ    T   Q  Q++  
Sbjct: 132 QLQQEKHQSVHHQELKPELQLMHQ-QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQ 190

Query: 182 QPQQGQTTP----VTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQ 237
           Q Q  Q       +  Q  + QQ Q++Q Q Q Q QQ Q    Q  Q+ QQ        Q
Sbjct: 191 QEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQ---QQEQLQQQ--------Q 239

Query: 238 QIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQL 297
           Q+ +    GQLQ   L Q     Q  Q Q Q L     Q+ Q  + Q Q+Q  Q    QL
Sbjct: 240 QLLLLQQQGQLQQQLLQQ-----QQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294

Query: 298 YQIQQVTMPAGQDLAQPM 315
            Q QQ  +   Q    P+
Sbjct: 295 LQQQQEQLQQQQLQPPPL 312



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 64/217 (29%), Positives = 90/217 (41%), Gaps = 8/217 (3%)

Query: 121 DELKPPKRQEEVRQSVTPAEPVQY-YFTLAQQPTA---VQVQGQQQGQQTTSSTTTIQPG 176
           +E +P +R+ +++Q     EP Q       QQP     +Q Q QQ GQQ  S     +  
Sbjct: 80  EETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQ 139

Query: 177 QIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEI 236
            +   + +         Q  + QQVQ  Q + Q Q +Q Q+   Q  QV+QQ      ++
Sbjct: 140 SVHHQELKPELQLMHQQQQLQPQQVQEQQ-RLQQQQEQLQTQQAQEQQVLQQQEQLQQQV 198

Query: 237 Q-QIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG 295
           Q Q  +Q    QLQ  +L Q     Q  Q Q Q      QQ      QQGQ Q  Q    
Sbjct: 199 QEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQ-QQLLQQ 257

Query: 296 QLYQIQQVTMPAGQ-DLAQPMFIQSANQPSDGQAPQV 331
           Q  Q+QQ  +   Q  L Q + +Q   Q    Q  Q+
Sbjct: 258 QQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294


>gi|11496974 nuclear transcription factor Y, alpha isoform 2 [Homo
           sapiens]
          Length = 318

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 54/194 (27%), Positives = 79/194 (40%), Gaps = 34/194 (17%)

Query: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
           T+ Q P +   QG QQ Q        IQ GQ +  Q QQGQT             QI+  
Sbjct: 60  TIMQVPVS-GTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQ------------QIIIQ 106

Query: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI---PVQLNAGQLQYIRL---------A 254
           QPQ      Q+ T Q + V  Q +  T E Q I   PV  +   LQ + +         A
Sbjct: 107 QPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPA 166

Query: 255 QPVSGTQVVQGQIQTLATNAQQITQT--------EVQQGQQQFSQFTDGQLYQIQQVTMP 306
             ++G Q+VQ    T  T++ Q T T         V  G         G +  IQ++ +P
Sbjct: 167 ASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLP 226

Query: 307 AGQDL-AQPMFIQS 319
             + L  +P+++ +
Sbjct: 227 GAEMLEEEPLYVNA 240



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 52/164 (31%), Positives = 65/164 (39%), Gaps = 28/164 (17%)

Query: 156 QVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQ--VGEGQQVQIVQAQPQGQAQ 213
           QVQGQ    Q +        GQ I+ Q   G      MQ  V   Q +Q +Q  P GQ  
Sbjct: 25  QVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQI- 83

Query: 214 QAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQT---L 270
           Q Q G                  Q + VQ   GQ Q I + QP   T V  GQ QT   +
Sbjct: 84  QIQGG------------------QAVQVQGQQGQTQQIIIQQP--QTAVTAGQTQTQQQI 123

Query: 271 ATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQP 314
           A   QQ+ QT   +GQ    Q  +     +QQVT+P    +  P
Sbjct: 124 AVQGQQVAQT--AEGQTIVYQPVNADGTILQQVTVPVSGMITIP 165


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 47/188 (25%), Positives = 85/188 (45%), Gaps = 18/188 (9%)

Query: 122 ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIA 181
           +L+ P++QE   Q   P +         QQ   +++  QQ+GQ         Q GQ+ + 
Sbjct: 222 QLELPEQQEG--QLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEH---QEGQLEVP 276

Query: 182 QPQQGQTTPVTMQVGEGQQVQIVQAQPQ------GQAQQAQSGTGQTMQVMQQIITNTGE 235
           + Q GQ   +  Q G+ + +   + QP+      GQ +  +   GQ   + QQ     G+
Sbjct: 277 EEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQ----EGQ 332

Query: 236 IQQIPVQLNAGQLQYIRLAQ-PVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTD 294
           ++Q+  Q   GQL+++   +  +   +  +GQ+        Q+ Q E QQGQ +  +  +
Sbjct: 333 LEQLEEQ--EGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEE 390

Query: 295 GQLYQIQQ 302
           GQL  + Q
Sbjct: 391 GQLKHLVQ 398



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 25/197 (12%)

Query: 122 ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIA 181
           +L+ P++QE   Q   P +         QQ   +++  QQ+GQ   S     Q GQ+ ++
Sbjct: 202 QLELPEQQEG--QLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQ---QEGQLELS 256

Query: 182 QPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPV 241
           + Q+GQ   +  Q G   Q+++ + Q  GQ +  +   GQ   + QQ      E Q    
Sbjct: 257 EQQEGQLKHLEHQEG---QLEVPEEQ-MGQLKYLEQQEGQLKHLDQQ------EKQPELP 306

Query: 242 QLNAGQLQYIRL--AQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQL-- 297
           +   GQL+++     QP    Q  +GQ++ L     Q+   E Q+GQ +  +  +GQL  
Sbjct: 307 EQQMGQLKHLEQQEGQPKHLEQQ-EGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGL 365

Query: 298 -----YQIQQVTMPAGQ 309
                 Q++Q+    GQ
Sbjct: 366 PEQQVLQLKQLEKQQGQ 382



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 30/192 (15%)

Query: 122 ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIA 181
           +LK   +QE  +Q   P + +     L QQ    +   QQ+GQ         Q GQ+   
Sbjct: 292 QLKHLDQQE--KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEE---QEGQLKHL 346

Query: 182 QPQQGQTTPVTMQVG-----EGQQVQIVQAQPQ-GQAQQAQSGTGQTMQVMQQIITNTGE 235
           + Q+GQ   +  Q G     E Q +Q+ Q + Q GQ +  +   GQ   ++QQ       
Sbjct: 347 EQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQ------- 399

Query: 236 IQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDG 295
                     GQL++  L Q     +  + Q++ L     Q+   E Q+GQ +  +   G
Sbjct: 400 ---------EGQLKH--LVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQG 448

Query: 296 QL-YQIQQVTMP 306
           QL    QQV  P
Sbjct: 449 QLEVPEQQVGQP 460



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 40/173 (23%), Positives = 71/173 (41%), Gaps = 23/173 (13%)

Query: 155 VQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQ 214
           VQ +GQ + Q+        Q GQ+   + Q+GQ   +  Q G+ +  +    QP+   Q+
Sbjct: 407 VQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQE 466

Query: 215 AQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNA 274
            +      +++ +Q       +++   QL   + Q               GQ + L    
Sbjct: 467 EKQ-----LELPEQQEGQVKHLEKQEAQLELPEQQV--------------GQPKHLEQQE 507

Query: 275 QQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ 327
           + +   E Q GQ +  +  +GQL  ++Q     GQ L QP+F  +  Q  D Q
Sbjct: 508 KHLEHPEQQDGQLKHLEQQEGQLKDLEQ---QKGQ-LEQPVFAPAPGQVQDIQ 556



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 40/188 (21%), Positives = 74/188 (39%), Gaps = 10/188 (5%)

Query: 124 KPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQI----I 179
           K P+ QE  +Q     E  Q      QQ    + Q  QQ  +       +   Q+    +
Sbjct: 80  KEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELV 139

Query: 180 IAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ-GQAQQAQSGTGQT-MQVMQQIITNTGEIQ 237
               Q G      +++ E Q+  +   + Q GQ +  +   GQ  +   Q+      E Q
Sbjct: 140 KRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQ 199

Query: 238 QIPVQLNAGQLQYIRLAQPVSGT----QVVQGQIQTLATNAQQITQTEVQQGQQQFSQFT 293
           +  ++L   Q   + L +   G     +  +GQ++       Q+  +E Q+GQ + S+  
Sbjct: 200 EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQ 259

Query: 294 DGQLYQIQ 301
           +GQL  ++
Sbjct: 260 EGQLKHLE 267


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 56/211 (26%), Positives = 86/211 (40%), Gaps = 10/211 (4%)

Query: 119  PRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQI 178
            P+  + P   Q  + Q ++P  P      L     AV +Q Q  G           P + 
Sbjct: 3773 PQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAV-LQQQHPGALGPQG-----PHRQ 3826

Query: 179  IIAQPQQGQTTPVTMQVGEGQQV-QIVQAQPQGQAQQ-AQSGTGQTMQVMQQIITNTGEI 236
            ++    +  ++P   Q G+G    ++V AQ Q Q QQ  Q G+   +  +QQ + +    
Sbjct: 3827 VLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQ 3886

Query: 237  QQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFS-QFTDG 295
             ++  Q   G LQ ++  Q +   Q +Q Q Q      QQ+ Q ++QQ QQQ   Q    
Sbjct: 3887 PKLSAQ-PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQ 3945

Query: 296  QLYQIQQVTMPAGQDLAQPMFIQSANQPSDG 326
            Q  Q QQ  +   Q   Q  F Q   Q   G
Sbjct: 3946 QQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 62/197 (31%), Positives = 77/197 (39%), Gaps = 34/197 (17%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQP---------TAVQVQGQQQGQQTTSSTTTIQPG 176
            P RQ  + QS   + P      LAQQ          TA Q Q QQQ QQ  S        
Sbjct: 3823 PHRQVLMTQSRVLSSP-----QLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQ 3877

Query: 177  QIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEI 236
            Q +++    GQ       +G  QQ+Q  Q Q   Q QQ Q    Q +Q  QQ+     + 
Sbjct: 3878 QSLMSH--SGQPKLSAQPMGSLQQLQ--QQQQLQQQQQLQQQQQQQLQQQQQL-----QQ 3928

Query: 237  QQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQ 296
            QQ+  Q    QLQ           Q  Q Q+Q      QQ  Q + QQ QQQ  Q   G 
Sbjct: 3929 QQLQQQQQQQQLQ-----------QQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGL 3977

Query: 297  LYQIQQVTMPAGQDLAQ 313
            L Q + +  P  Q   Q
Sbjct: 3978 LNQSRTLLSPQQQQQQQ 3994



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 32/99 (32%), Positives = 39/99 (39%), Gaps = 6/99 (6%)

Query: 150  QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
            QQ    Q Q QQQ QQ       +Q  Q+   Q QQ       +Q  + QQ+Q  Q Q Q
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQ------QLQQQQQQQLQQQQQQLQ 3956

Query: 210  GQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQL 248
             Q QQ Q    Q  Q  Q  + N       P Q    Q+
Sbjct: 3957 QQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV 3995



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 67/272 (24%), Positives = 96/272 (35%), Gaps = 33/272 (12%)

Query: 86   IHTEDNKRRTLQRNDIAMAITKFDQFDF-LIDIVPRDELKPPKRQEEVRQSVTPAEPVQY 144
            +H +  K    ++     A  +F + D   + +V   + K  K+ ++VR+       +  
Sbjct: 3534 VHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMA 3593

Query: 145  YFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQ---IIIAQPQQGQTTP----VTMQVGE 197
             +   QQ    Q Q QQQ QQ  S+   + P Q   ++   P  GQ  P       Q   
Sbjct: 3594 EYRNKQQQ---QQQQQQQQQQQHSAVLALSPSQSPRLLTKLP--GQLLPGHGLQPPQGPP 3648

Query: 198  GQQVQIVQAQPQGQAQQAQSG-----TGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIR 252
            G Q   ++  P G A   Q G     T    Q  QQ     G +         G L    
Sbjct: 3649 GGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRS 3708

Query: 253  LAQPVSGTQVVQGQIQTLATN-AQQITQTEVQQGQQQF--------SQFTDGQLYQIQQV 303
            L       Q  Q Q+Q      AQ++ Q + QQ QQQ          Q   G   Q  Q 
Sbjct: 3709 LGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQA 3768

Query: 304  TMPAGQDLAQP-----MFIQSANQPSDGQAPQ 330
              P  Q L  P     + +Q  + P   Q PQ
Sbjct: 3769 LGPKPQGLMPPSSHQGLLVQQLS-PQPPQGPQ 3799



 Score = 32.3 bits (72), Expect = 0.61
 Identities = 53/232 (22%), Positives = 85/232 (36%), Gaps = 29/232 (12%)

Query: 119  PRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTT-IQPGQ 177
            P   L+  ++Q++++Q     +  Q      QQ    Q+Q QQQ QQ        +Q  Q
Sbjct: 3893 PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQ 3952

Query: 178  IIIAQPQQGQTTPVTMQVGEGQ-----QVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITN 232
              + Q QQ Q      Q  + Q     Q + + +  Q Q QQ   G G   + +Q   ++
Sbjct: 3953 QQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQH-FSS 4011

Query: 233  TGEIQQIPVQLNAGQLQY----IRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQ 288
             G +   P  L  G+ Q        ++   G    QG    + T  + +     + G+ +
Sbjct: 4012 PGALG--PTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA---TEPGEVK 4066

Query: 289  FSQFTDGQLYQIQQVTMP-------------AGQDLAQPMFIQSANQPSDGQ 327
             S   D QL  +Q    P              GQ   Q   + +A   S GQ
Sbjct: 4067 PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQ 4118


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 56/186 (30%), Positives = 71/186 (38%), Gaps = 26/186 (13%)

Query: 152 PTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQ 211
           P    +Q QQQ QQ        Q   ++  QPQQ       MQ+ + QQ QI Q QP  Q
Sbjct: 396 PETHMLQQQQQAQQQQ------QQHPVLHLQPQQ------IMQLQQQQQQQISQ-QPYPQ 442

Query: 212 A-------QQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQ 264
                   QQ Q       Q  QQ +    +    P QL+  Q Q     QP      +Q
Sbjct: 443 QPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQL----QPFQQQHALQ 498

Query: 265 GQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQPMFIQSANQPS 324
            Q   L  +  Q+ Q ++ Q QQQ S     Q  QIQQ  +       Q   +QS   P 
Sbjct: 499 QQFHQLQQH--QLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPH 556

Query: 325 DGQAPQ 330
             Q  Q
Sbjct: 557 LSQTSQ 562



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 57/194 (29%), Positives = 70/194 (36%), Gaps = 16/194 (8%)

Query: 155 VQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTT---PVTMQVGEG---QQVQIVQAQP 208
           +Q Q Q Q QQ       +QP QI+  Q QQ Q     P   Q       QQ Q  QA P
Sbjct: 401 LQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHP 460

Query: 209 QGQAQQAQSGTGQTMQVMQQI---------ITNTGEIQQIPVQLNAGQLQYIRLAQPVSG 259
              +QQ      Q +   QQ+               +QQ   QL   QLQ  +LAQ    
Sbjct: 461 HQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520

Query: 260 TQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQPMFIQS 319
             ++Q Q Q      QQ+ +   QQ QQQ    T   L Q  Q           P   Q 
Sbjct: 521 HSLLQQQ-QQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQ 579

Query: 320 ANQPSDGQAPQVTG 333
              P   Q  Q+ G
Sbjct: 580 QQPPPSPQQHQLFG 593



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 32/102 (31%), Positives = 44/102 (43%), Gaps = 8/102 (7%)

Query: 119 PRDELKPPKRQEEVRQSVTPAEP----VQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQ 174
           P+ +L+P ++Q  ++Q     +      Q    L QQ + +Q Q QQQ QQ        Q
Sbjct: 484 PQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQ 543

Query: 175 PGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQ 216
             Q    Q  Q QT P   Q  +  Q Q+   QP  Q QQ Q
Sbjct: 544 QQQ----QQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQ 581



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 18/111 (16%)

Query: 119 PRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQI 178
           P+ +L PP++    +Q +   +P Q    L QQ   +Q Q Q Q QQ       +Q    
Sbjct: 471 PQQQLHPPQQLHRPQQQL---QPFQQQHALQQQFHQLQ-QHQLQQQQLAQ----LQQQHS 522

Query: 179 IIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSG--TGQTMQVMQ 227
           ++ Q QQ Q         + QQ+Q +  Q Q Q  Q+Q+     QT Q +Q
Sbjct: 523 LLQQQQQQQI--------QQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQ 565


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 84/218 (38%), Gaps = 30/218 (13%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
            P   ++V   +   +PV    T    P  V     Q+   + +ST+ IQ       +PQQ
Sbjct: 2212 PGAPQQVMTQIIRGQPVS---TAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQ 2268

Query: 186  GQTTPVTMQVGE------GQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI 239
            GQ      Q+ +      G Q   V  Q QGQ       TGQ   + Q +    G  QQ+
Sbjct: 2269 GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQT------TGQLQLIPQGVTVLPGPGQQL 2322

Query: 240  -PVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLY 298
                +  G +Q   L  P++ T        T +T    ++ T    G+Q+ S+ +  Q+ 
Sbjct: 2323 MQAAMPNGTVQRF-LFTPLATTAT------TASTTTTTVSTTAAGTGEQRQSKLSP-QMQ 2374

Query: 299  QIQQVTMPAGQDL------AQPMFIQSANQPSDGQAPQ 330
              Q  T+P  Q        AQP   Q + QP     PQ
Sbjct: 2375 VHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQ 2412



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 18/103 (17%)

Query: 150  QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTP-----VTMQVGEGQQVQIV 204
            Q+PT +          T+S+T+TI P Q ++  P  G  T      +T +VG    V   
Sbjct: 2049 QKPTVIATSTTSP---TSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQ 2105

Query: 205  QAQPQGQ-----AQQAQSGTGQTMQVMQQII----TNTGEIQQ 238
            Q +   Q      +Q QS +G  +QV Q+++    ++TG  QQ
Sbjct: 2106 QNKNFHQTFATWVKQGQSNSG-VVQVQQKVLGIIPSSTGTSQQ 2147


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 56/218 (25%), Positives = 84/218 (38%), Gaps = 30/218 (13%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
            P   ++V   +   +PV    T    P  V     Q+   + +ST+ IQ       +PQQ
Sbjct: 2086 PGAPQQVMTQIIRGQPVS---TAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQ 2142

Query: 186  GQTTPVTMQVGE------GQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQI 239
            GQ      Q+ +      G Q   V  Q QGQ       TGQ   + Q +    G  QQ+
Sbjct: 2143 GQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQT------TGQLQLIPQGVTVLPGPGQQL 2196

Query: 240  -PVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLY 298
                +  G +Q   L  P++ T        T +T    ++ T    G+Q+ S+ +  Q+ 
Sbjct: 2197 MQAAMPNGTVQRF-LFTPLATTAT------TASTTTTTVSTTAAGTGEQRQSKLSP-QMQ 2248

Query: 299  QIQQVTMPAGQDL------AQPMFIQSANQPSDGQAPQ 330
              Q  T+P  Q        AQP   Q + QP     PQ
Sbjct: 2249 VHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQ 2286



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/177 (26%), Positives = 79/177 (44%), Gaps = 33/177 (18%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQ-QTTSSTTTIQPGQ----III 180
            P +Q +V+ + +   P+Q + +L      +  QGQ Q Q Q  SST T+  GQ    + +
Sbjct: 2361 PGQQSQVQTTTSQPIPIQPHTSLQ-----IPSQGQPQSQPQVQSSTQTLSSGQTLNQVTV 2415

Query: 181  AQP-----QQGQTTPVTMQVGE-GQQVQI---VQAQPQGQAQQAQSGTGQTMQVMQQIIT 231
            + P     Q  Q  P  + V +  QQVQ+   +Q+Q   Q Q  QSG  Q +++      
Sbjct: 2416 SSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKL------ 2469

Query: 232  NTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQ 288
                  Q+P+Q+   Q   ++  Q  +   V    +Q      QQ+   + ++ QQQ
Sbjct: 2470 ------QLPIQIQ--QSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQ 2518



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 53/206 (25%), Positives = 81/206 (39%), Gaps = 31/206 (15%)

Query: 125  PPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQ 184
            P + + + +  V     V  +     QPT  Q    Q   Q+   +       + +  P 
Sbjct: 2288 PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPS 2347

Query: 185  QGQ---TTPVTMQVGEGQQVQIVQAQP-------------QGQAQ---QAQSGTGQTM-- 223
            Q +   +TP  +  G+  QVQ   +QP             QGQ Q   Q QS T QT+  
Sbjct: 2348 QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSST-QTLSS 2406

Query: 224  -QVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEV 282
             Q + Q+  ++    Q+  Q+   Q Q I + Q     QV+  QIQ+      Q  Q+ V
Sbjct: 2407 GQTLNQVTVSSPSRPQL--QIQQPQPQVIAVPQLQQQVQVL-SQIQSQVVAQIQAQQSGV 2463

Query: 283  QQGQQ-----QFSQFTDGQLYQIQQV 303
             Q  +     Q  Q +  Q +QIQ V
Sbjct: 2464 PQQIKLQLPIQIQQSSAVQTHQIQNV 2489



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 18/103 (17%)

Query: 150  QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTP-----VTMQVGEGQQVQIV 204
            Q+PT +          T+S+T+TI P Q ++  P  G  T      +T +VG    V   
Sbjct: 1923 QKPTVIATSTTSP---TSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQ 1979

Query: 205  QAQPQGQ-----AQQAQSGTGQTMQVMQQII----TNTGEIQQ 238
            Q +   Q      +Q QS +G  +QV Q+++    ++TG  QQ
Sbjct: 1980 QNKNFHQTFATWVKQGQSNSG-VVQVQQKVLGIIPSSTGTSQQ 2021


>gi|38570099 glutamine-rich 1 [Homo sapiens]
          Length = 776

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 64/245 (26%), Positives = 93/245 (37%), Gaps = 40/245 (16%)

Query: 126 PKRQEEVRQSVTPAEPVQYYFTLAQQPTAV------------------QVQGQQQGQQTT 167
           P+ Q+E +  V   + VQ    + Q P  V                  QVQ Q QGQ   
Sbjct: 86  PQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQIQGQAPQ 145

Query: 168 SSTTTIQPGQIIIAQPQQGQTTPVTMQ-VGEGQQVQIVQAQPQ---GQAQQAQSGTGQTM 223
           S+  +IQ   +    P Q Q   + +Q V   QQ+Q  +   +    Q  QAQ   GQ++
Sbjct: 146 SAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSL 205

Query: 224 QVMQQI-ITNTGEIQQIPVQLNAGQLQYIRLA-----QPVSGTQVVQGQIQTLATNAQQI 277
              QQI I   G +   P Q  + +    R+      QPV   +V      + A + Q +
Sbjct: 206 AGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPV 265

Query: 278 -TQTEVQQGQQQ--------FSQFTDGQLYQIQ-QVTMPAGQDLAQPMFIQSANQPSDGQ 327
            T   + QGQQQ                LY     +T P G+    P++  SA    D Q
Sbjct: 266 ATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVY--SAQPRGDPQ 323

Query: 328 APQVT 332
              +T
Sbjct: 324 QQSIT 328



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 50/200 (25%), Positives = 79/200 (39%), Gaps = 34/200 (17%)

Query: 141 PVQYYFTLAQQPTAVQV---QGQQQGQQTTSSTTTIQPGQIIIAQPQ-QGQTTPVTMQVG 196
           P+   + ++ QP A  +   QGQQQ      S  +++P  + +        T  +T   G
Sbjct: 253 PITVSYAISGQPVATVLAIPQGQQQ------SYVSLRPDLLTVDSAHLYSATGTITSPTG 306

Query: 197 EGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQP 256
           E   + +  AQP+G  QQ       T   + Q   N   +   P  L A +L+  +  + 
Sbjct: 307 ETWTIPVYSAQPRGDPQQQSI----THIAIPQEAYNAVHVSGSPTALAAVKLEDDK-EKM 361

Query: 257 VSGTQVVQGQ----IQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAG--QD 310
           V  T VV+      +QTLA +                +QF +G ++    V   AG  Q+
Sbjct: 362 VGTTSVVKNSHEEVVQTLANSLFP-------------AQFMNGNIHIPVAVQAVAGTYQN 408

Query: 311 LAQPMFIQSANQPSDGQAPQ 330
            AQ + I    Q    Q PQ
Sbjct: 409 TAQTVHIWDPQQQPQQQTPQ 428



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 48/171 (28%), Positives = 69/171 (40%), Gaps = 7/171 (4%)

Query: 151 QPTAVQVQGQQQGQQTTSSTTTIQPGQII-IAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           Q TA      QQG     + +T   G ++ +A P      P T Q  + Q  Q  Q Q Q
Sbjct: 46  QQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQQEQQIQVQQPQQVQVQ 105

Query: 210 GQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQT 269
            Q QQ+       +     +   T +  Q+ VQ+   Q Q  + A P   T  +Q    +
Sbjct: 106 VQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQI---QGQAPQSAAPSIQTPSLQSPSPS 162

Query: 270 LATNAQQITQTEVQQGQQ-QFSQFTDGQL-YQIQQVTMPAGQDLAQPMFIQ 318
               A QI    VQ  QQ Q ++  +  + +Q  Q  + AGQ LA    IQ
Sbjct: 163 -QLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSLAGGQQIQ 212


>gi|38570097 glutamine-rich 1 [Homo sapiens]
          Length = 776

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 64/245 (26%), Positives = 93/245 (37%), Gaps = 40/245 (16%)

Query: 126 PKRQEEVRQSVTPAEPVQYYFTLAQQPTAV------------------QVQGQQQGQQTT 167
           P+ Q+E +  V   + VQ    + Q P  V                  QVQ Q QGQ   
Sbjct: 86  PQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQIQGQAPQ 145

Query: 168 SSTTTIQPGQIIIAQPQQGQTTPVTMQ-VGEGQQVQIVQAQPQ---GQAQQAQSGTGQTM 223
           S+  +IQ   +    P Q Q   + +Q V   QQ+Q  +   +    Q  QAQ   GQ++
Sbjct: 146 SAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSL 205

Query: 224 QVMQQI-ITNTGEIQQIPVQLNAGQLQYIRLA-----QPVSGTQVVQGQIQTLATNAQQI 277
              QQI I   G +   P Q  + +    R+      QPV   +V      + A + Q +
Sbjct: 206 AGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPV 265

Query: 278 -TQTEVQQGQQQ--------FSQFTDGQLYQIQ-QVTMPAGQDLAQPMFIQSANQPSDGQ 327
            T   + QGQQQ                LY     +T P G+    P++  SA    D Q
Sbjct: 266 ATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVY--SAQPRGDPQ 323

Query: 328 APQVT 332
              +T
Sbjct: 324 QQSIT 328



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 50/200 (25%), Positives = 79/200 (39%), Gaps = 34/200 (17%)

Query: 141 PVQYYFTLAQQPTAVQV---QGQQQGQQTTSSTTTIQPGQIIIAQPQ-QGQTTPVTMQVG 196
           P+   + ++ QP A  +   QGQQQ      S  +++P  + +        T  +T   G
Sbjct: 253 PITVSYAISGQPVATVLAIPQGQQQ------SYVSLRPDLLTVDSAHLYSATGTITSPTG 306

Query: 197 EGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQP 256
           E   + +  AQP+G  QQ       T   + Q   N   +   P  L A +L+  +  + 
Sbjct: 307 ETWTIPVYSAQPRGDPQQQSI----THIAIPQEAYNAVHVSGSPTALAAVKLEDDK-EKM 361

Query: 257 VSGTQVVQGQ----IQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAG--QD 310
           V  T VV+      +QTLA +                +QF +G ++    V   AG  Q+
Sbjct: 362 VGTTSVVKNSHEEVVQTLANSLFP-------------AQFMNGNIHIPVAVQAVAGTYQN 408

Query: 311 LAQPMFIQSANQPSDGQAPQ 330
            AQ + I    Q    Q PQ
Sbjct: 409 TAQTVHIWDPQQQPQQQTPQ 428



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 48/171 (28%), Positives = 69/171 (40%), Gaps = 7/171 (4%)

Query: 151 QPTAVQVQGQQQGQQTTSSTTTIQPGQII-IAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           Q TA      QQG     + +T   G ++ +A P      P T Q  + Q  Q  Q Q Q
Sbjct: 46  QQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQQEQQIQVQQPQQVQVQ 105

Query: 210 GQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQT 269
            Q QQ+       +     +   T +  Q+ VQ+   Q Q  + A P   T  +Q    +
Sbjct: 106 VQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQI---QGQAPQSAAPSIQTPSLQSPSPS 162

Query: 270 LATNAQQITQTEVQQGQQ-QFSQFTDGQL-YQIQQVTMPAGQDLAQPMFIQ 318
               A QI    VQ  QQ Q ++  +  + +Q  Q  + AGQ LA    IQ
Sbjct: 163 -QLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSLAGGQQIQ 212


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 51/196 (26%), Positives = 78/196 (39%), Gaps = 22/196 (11%)

Query: 128  RQEEVRQSVTPAEPVQYYFTLAQQPTA-VQVQGQQQGQQTTSSTTTI---QPGQIIIAQP 183
            + ++ +  + P  P     +   QPTA VQVQ  Q  QQ +   TT+   +PG ++    
Sbjct: 2782 KMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTG-- 2839

Query: 184  QQGQTTPVTMQVGEGQQVQIVQAQPQGQAQ-------QAQSGTGQTMQVMQQIITNTGEI 236
                TT   +QV    +V   Q Q QGQ Q       Q        + V   ++++ G +
Sbjct: 2840 ----TTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPG-V 2894

Query: 237  QQIPVQLNAGQLQYIRLAQPVSGTQVVQGQI---QTLATNAQQITQTEVQQGQQQFSQFT 293
              +P+ + AG    I   Q  +G  VV   +   Q L    Q + Q +  Q Q       
Sbjct: 2895 TTLPMNV-AGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAA 2953

Query: 294  DGQLYQIQQVTMPAGQ 309
              Q    QQ+T P  Q
Sbjct: 2954 VQQKITAQQITTPGAQ 2969



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 56/198 (28%), Positives = 75/198 (37%), Gaps = 13/198 (6%)

Query: 126  PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
            P  Q + +  +    P      LA+ P              T+    +    + I QPQ+
Sbjct: 2854 PTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQK 2913

Query: 186  --GQTT---PVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIP 240
              GQT    PV MQ     + Q VQ Q   Q Q AQ       ++  Q IT  G  Q++ 
Sbjct: 2914 AAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVA 2973

Query: 241  VQLN-AGQLQY----IRLAQPVSGTQVVQGQIQT--LATNAQQITQTEVQQGQQQFSQFT 293
                 A + Q+    I  AQ ++G Q VQ QIQ   L    QQ T     Q     SQ  
Sbjct: 2974 YAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQA 3033

Query: 294  DGQLYQIQQVTMPAGQDL 311
              Q   + Q T  AGQ +
Sbjct: 3034 SPQTVALTQAT-AAGQQV 3050



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 17/127 (13%)

Query: 118  VPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQ 177
            +   ++  P  Q++V  +  PA   Q+  T   Q  A ++ G QQ Q      T IQ  +
Sbjct: 2958 ITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQ--AQKLAGAQQVQ------TQIQVAK 3009

Query: 178  IIIAQPQQGQTTPVT--MQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGE 235
            +     QQ   TPV    QV    Q    QA PQ  A    +  GQ +Q++  +      
Sbjct: 3010 LPQVVQQQ---TPVASIQQVASASQ----QASPQTVALTQATAAGQQVQMIPAVTATAQV 3062

Query: 236  IQQIPVQ 242
            +QQ  +Q
Sbjct: 3063 VQQKLIQ 3069



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 51/173 (29%), Positives = 63/173 (36%), Gaps = 13/173 (7%)

Query: 135  SVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQ 194
            SVT +  V    T  Q P    V    Q         TI P    + + QQ Q      Q
Sbjct: 2671 SVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQ 2730

Query: 195  VGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA-GQLQYIRL 253
              + QQ Q  Q     Q QQ Q+ T   +QV Q      G+ Q  P Q+ A G+L    L
Sbjct: 2731 QQQQQQQQQQQ-----QQQQQQTTTTSQVQVPQ----IQGQAQS-PAQIKAVGKLTPEHL 2780

Query: 254  AQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMP 306
             +     Q +Q   Q     AQ        Q Q Q SQ    Q  Q+  VT P
Sbjct: 2781 IK--MQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAP 2831


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 59/216 (27%), Positives = 81/216 (37%), Gaps = 33/216 (15%)

Query: 119  PRDELKPPKRQEEVRQSVTPA------EPVQYYFTLAQQPTA-VQVQGQQQGQQTTSSTT 171
            P   + PP    +  QS  P+      +P ++   L Q+P+  V  Q    G   TS+  
Sbjct: 1959 PAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRH---LQQRPSGYVHQQAPTYGHGLTSTQR 2015

Query: 172  TIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIIT 231
                 Q +   P     TP++ Q G    V+     P+ Q QQ Q    Q  Q  QQ   
Sbjct: 2016 FSH--QTLQQTPMISTMTPMSAQ-GVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQ--- 2069

Query: 232  NTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQ 291
                      Q    Q  +IR  Q     Q+++ Q Q      QQ  Q + QQ QQQ  Q
Sbjct: 2070 ----------QQQQQQQYHIRQQQQ---QQILRQQQQ----QQQQQQQQQQQQQQQQQQQ 2112

Query: 292  FTDGQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQ 327
                Q  Q QQ   P  Q  +QP F +   Q +  Q
Sbjct: 2113 QQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQ 2148



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 14/123 (11%)

Query: 127  KRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQG 186
            ++Q++ +Q     +  QY+    QQ   ++ Q QQQ QQ                Q QQ 
Sbjct: 2060 QQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQ----------QQQQQQ 2109

Query: 187  QTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAG 246
            Q      Q  + QQ    Q QPQ Q Q  + G  QT Q  Q        ++Q+  QL+  
Sbjct: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQ----TAALVRQLQQQLSNT 2165

Query: 247  QLQ 249
            Q Q
Sbjct: 2166 QPQ 2168



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 39/127 (30%), Positives = 45/127 (35%), Gaps = 8/127 (6%)

Query: 156  QVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQA 215
            Q Q QQQ QQ        Q  Q  I Q QQ Q           QQ Q  Q Q Q Q QQ 
Sbjct: 2055 QQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILR--------QQQQQQQQQQQQQQQQQ 2106

Query: 216  QSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQ 275
            Q    Q  Q  QQ        Q  P      Q Q ++  Q    T  +  Q+Q   +N Q
Sbjct: 2107 QQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166

Query: 276  QITQTEV 282
                T +
Sbjct: 2167 PQPSTNI 2173



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 37/116 (31%), Positives = 45/116 (38%), Gaps = 4/116 (3%)

Query: 150  QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
            QQ    Q Q QQQ QQ        Q  QI+  Q QQ Q      Q  + QQ Q  Q   Q
Sbjct: 2059 QQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQ 2118

Query: 210  GQAQQAQSGTGQTM---QVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQV 262
             Q QQA     Q     Q  +Q +  T + QQ    +   Q Q +   QP   T +
Sbjct: 2119 QQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQ-QQLSNTQPQPSTNI 2173



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 32/127 (25%), Positives = 43/127 (33%), Gaps = 11/127 (8%)

Query: 204  VQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVV 263
            +Q +P G   Q     G  +   Q+    T  +QQ P+         I    P+S   V 
Sbjct: 1991 LQQRPSGYVHQQAPTYGHGLTSTQRFSHQT--LQQTPM---------ISTMTPMSAQGVQ 2039

Query: 264  QGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQPMFIQSANQP 323
             G   T     QQ  Q + QQ QQQ  Q    Q  Q   +     Q + +    Q   Q 
Sbjct: 2040 AGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQ 2099

Query: 324  SDGQAPQ 330
               Q  Q
Sbjct: 2100 QQQQQQQ 2106


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 46/163 (28%), Positives = 60/163 (36%), Gaps = 16/163 (9%)

Query: 182 QPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPV 241
           +P+QG T P+     +    Q+    P          T Q  Q  QQ      + QQ   
Sbjct: 550 EPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQ----QQQQQQQQQ 605

Query: 242 QLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQ 301
           Q    Q Q  +  Q  S     Q Q Q  + +AQQ  Q + QQ QQQ  Q    Q  Q Q
Sbjct: 606 QQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQ 665

Query: 302 QVTMPAGQDLAQP------------MFIQSANQPSDGQAPQVT 332
             + PA    +QP            +  Q  NQP  G   QV+
Sbjct: 666 PSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVS 708



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 39/121 (32%), Positives = 53/121 (43%), Gaps = 15/121 (12%)

Query: 150 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           QQ    Q Q QQQ QQ++           I AQ QQ Q + ++ Q  + QQ Q  Q Q Q
Sbjct: 606 QQQQQQQQQQQQQQQQSS-----------ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQ 654

Query: 210 GQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGT--QVVQGQI 267
            Q QQ Q     + Q  Q + +    + + P+ L    L      QP++G   QV Q Q 
Sbjct: 655 QQQQQQQQQQQPSSQPAQSLPSQ--PLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQR 712

Query: 268 Q 268
           Q
Sbjct: 713 Q 713



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 43/178 (24%), Positives = 64/178 (35%), Gaps = 25/178 (14%)

Query: 127 KRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQP--- 183
           ++Q++ + S++  +  Q      QQ    Q Q QQQ QQ +S      P Q ++  P   
Sbjct: 627 QQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPL 686

Query: 184 ------QQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQ 237
                 QQ Q  P+    G G QV   Q Q Q       +G   +        T +G + 
Sbjct: 687 QQKLLLQQMQNQPI---AGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMN 743

Query: 238 QIPVQLNAGQLQYIRLAQPVSGTQVVQGQI----QTLATNAQQITQTEVQQGQQQFSQ 291
                LN          Q +   Q +Q QI    Q L    Q +   E    Q Q ++
Sbjct: 744 SQQSLLN---------QQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINR 792


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 44/153 (28%), Positives = 52/153 (33%), Gaps = 8/153 (5%)

Query: 186 GQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA 245
           GQ  P T  +       +  A PQ Q Q  Q    Q  Q  Q        +QQ   Q   
Sbjct: 127 GQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ 186

Query: 246 GQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ--------ITQTEVQQGQQQFSQFTDGQL 297
            Q Q  + A       VVQ Q Q      QQ          Q ++QQ QQQ  +    QL
Sbjct: 187 QQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQL 246

Query: 298 YQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 330
            Q QQ      Q   Q +  Q   Q    Q PQ
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ 279



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 59/215 (27%), Positives = 82/215 (38%), Gaps = 19/215 (8%)

Query: 123 LKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQ 182
           L+  ++Q++ +Q       +Q  F    Q    Q Q QQQ QQ           Q  I Q
Sbjct: 177 LQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ---QQQLQQQQQQQQHLIKLHHQNQQQIQQ 233

Query: 183 PQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQ 242
            QQ       +Q+ + QQ Q  Q Q Q QA QAQ    Q    MQQ        Q +P Q
Sbjct: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ--PPMQQ--PQPPPSQALPQQ 289

Query: 243 LNAGQLQYIRLAQPVSGTQ---VVQGQIQTLATNAQQ---ITQTEVQQGQQQFSQFTDGQ 296
           L   Q+ + +  QP    Q   V Q Q   L   +Q    ++Q +   GQ  ++Q     
Sbjct: 290 LQ--QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ----P 343

Query: 297 LYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQV 331
             +  +  M   Q   QP   Q        QA Q+
Sbjct: 344 PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 56/210 (26%), Positives = 74/210 (35%), Gaps = 24/210 (11%)

Query: 126 PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
           P+ Q +++Q     +  Q  F   QQ    Q Q QQQ QQ  +  + +Q         QQ
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ---------QQ 199

Query: 186 GQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA 245
            Q       V + QQ+Q  Q Q Q   +       Q  Q  QQ+        Q   QL  
Sbjct: 200 FQAV-----VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL--------QRIAQLQL 246

Query: 246 GQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQ--IQQV 303
            Q Q  +  Q     Q +Q Q        QQ      Q   QQ  Q    Q +Q   Q  
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306

Query: 304 TMPAGQDLAQPMFIQSANQPSDGQAPQVTG 333
             P  Q+    +  QS  QP   QA  + G
Sbjct: 307 QPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 59/232 (25%), Positives = 81/232 (34%), Gaps = 40/232 (17%)

Query: 127 KRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQ--QGQQTTSSTTTIQPGQIIIAQ-- 182
           ++Q++ +Q++    P+Q       QP   Q   QQ  Q   T       QP Q  +AQ  
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 183 ----PQQGQTTPVTMQVGE--GQQ---------------VQIVQAQPQGQAQQAQSGTGQ 221
               P Q QT P+  Q     GQ                VQ    QPQ Q QQ    T Q
Sbjct: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374

Query: 222 TMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTE 281
             Q++         +Q I   L  G +       P +    +     ++    Q + Q  
Sbjct: 375 AAQMV------APGVQMITEALAQGGMHIRARFPPTTAVSAIPS--SSIPLGRQPMAQVS 426

Query: 282 VQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQPMFIQSANQP----SDGQAP 329
            Q      S  + GQ  Q  Q   P  Q   QP   Q ++QP    S G AP
Sbjct: 427 -QSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG--QPSSQPNSNVSSGPAP 475


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 44/153 (28%), Positives = 52/153 (33%), Gaps = 8/153 (5%)

Query: 186 GQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA 245
           GQ  P T  +       +  A PQ Q Q  Q    Q  Q  Q        +QQ   Q   
Sbjct: 127 GQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQ 186

Query: 246 GQLQYIRLAQPVSGTQVVQGQIQTLATNAQQ--------ITQTEVQQGQQQFSQFTDGQL 297
            Q Q  + A       VVQ Q Q      QQ          Q ++QQ QQQ  +    QL
Sbjct: 187 QQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQL 246

Query: 298 YQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 330
            Q QQ      Q   Q +  Q   Q    Q PQ
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQ 279



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 59/215 (27%), Positives = 82/215 (38%), Gaps = 19/215 (8%)

Query: 123 LKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQ 182
           L+  ++Q++ +Q       +Q  F    Q    Q Q QQQ QQ           Q  I Q
Sbjct: 177 LQQQQQQQQQQQFQAQQSAMQQQFQAVVQQ---QQQLQQQQQQQQHLIKLHHQNQQQIQQ 233

Query: 183 PQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQ 242
            QQ       +Q+ + QQ Q  Q Q Q QA QAQ    Q    MQQ        Q +P Q
Sbjct: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ--PPMQQ--PQPPPSQALPQQ 289

Query: 243 LNAGQLQYIRLAQPVSGTQ---VVQGQIQTLATNAQQ---ITQTEVQQGQQQFSQFTDGQ 296
           L   Q+ + +  QP    Q   V Q Q   L   +Q    ++Q +   GQ  ++Q     
Sbjct: 290 LQ--QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ----P 343

Query: 297 LYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQV 331
             +  +  M   Q   QP   Q        QA Q+
Sbjct: 344 PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 56/210 (26%), Positives = 74/210 (35%), Gaps = 24/210 (11%)

Query: 126 PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQ 185
           P+ Q +++Q     +  Q  F   QQ    Q Q QQQ QQ  +  + +Q         QQ
Sbjct: 149 PQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ---------QQ 199

Query: 186 GQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNA 245
            Q       V + QQ+Q  Q Q Q   +       Q  Q  QQ+        Q   QL  
Sbjct: 200 FQAV-----VQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQL--------QRIAQLQL 246

Query: 246 GQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQ--IQQV 303
            Q Q  +  Q     Q +Q Q        QQ      Q   QQ  Q    Q +Q   Q  
Sbjct: 247 QQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQ 306

Query: 304 TMPAGQDLAQPMFIQSANQPSDGQAPQVTG 333
             P  Q+    +  QS  QP   QA  + G
Sbjct: 307 QPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 30/106 (28%), Positives = 42/106 (39%), Gaps = 17/106 (16%)

Query: 125 PPKRQEEVRQSVTPAEPVQYYFT------------LAQQPTAVQVQGQQQGQQTTSSTTT 172
           PP+ Q +   S   A P Q  +T            + Q P   QVQ QQ   QT  +   
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378

Query: 173 IQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSG 218
           + PG + ++Q     + P+      GQQVQ  Q+ P       Q G
Sbjct: 379 VAPG-VQVSQ----SSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG 419



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 35/125 (28%), Positives = 47/125 (37%), Gaps = 25/125 (20%)

Query: 127 KRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQ--QGQQTTSSTTTIQPGQIIIAQ-- 182
           ++Q++ +Q++    P+Q       QP   Q   QQ  Q   T       QP Q  +AQ  
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 183 ----PQQGQTTPVTMQVGE--GQQ---------------VQIVQAQPQGQAQQAQSGTGQ 221
               P Q QT P+  Q     GQ                VQ    QPQ Q QQ    T Q
Sbjct: 315 PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374

Query: 222 TMQVM 226
             Q++
Sbjct: 375 AAQMV 379


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 59/214 (27%), Positives = 70/214 (32%), Gaps = 49/214 (22%)

Query: 119 PRDELKP--PKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPG 176
           P+ +  P  P  Q + +Q   P  P Q   T AQ   A Q Q   Q QQ           
Sbjct: 418 PKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPA-QAQATPQHQQ----------- 465

Query: 177 QIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEI 236
           Q+ + Q QQ Q  P   Q   G   Q    Q Q Q QQ Q+    T Q           I
Sbjct: 466 QLFLKQQQQQQQPPPAQQQPAGTFYQ----QQQAQTQQFQAVHPATQQPA---------I 512

Query: 237 QQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQ 296
            Q PV    G  Q +                       Q   Q + QQ QQQ  Q     
Sbjct: 513 AQFPVVSQGGSQQQLM----------------------QNFYQQQQQQQQQQQQQQLATA 550

Query: 297 LYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQ 330
           L+Q Q +T  A       M      QP    APQ
Sbjct: 551 LHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ 584


>gi|62865633 Sp3 transcription factor isoform 2 [Homo sapiens]
          Length = 713

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 60/217 (27%), Positives = 88/217 (40%), Gaps = 47/217 (21%)

Query: 164 QQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA-------------QPQG 210
           QQ T+S TT   GQ+  +  Q         +  + Q +Q+  A             QP  
Sbjct: 282 QQNTNSLTT-SSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTS 340

Query: 211 QAQQAQSGTGQTMQVMQQIITNTGE--IQQIPVQLNAG----QLQYIRLAQPVS-GTQVV 263
           QAQ  Q  T QT+  +Q    N  +  +Q + +QLN G    Q Q +  +  V+  T  V
Sbjct: 341 QAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQVTWQTFQV 400

Query: 264 QG-----QIQTLATNAQQITQTEVQQ---GQQQFS--------QFTDGQLYQIQQVTMPA 307
           QG      +Q   T AQQIT T VQ    GQ              + GQL  +Q VT+ +
Sbjct: 401 QGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNLQTVTVNS 460

Query: 308 ----------GQDLAQPMFIQSANQPSDGQAPQVTGD 334
                     G++   P  I+   +  D +  Q++GD
Sbjct: 461 IDSAGIQLHPGENADSPADIRIKEEEPDPEEWQLSGD 497


>gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens]
          Length = 781

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 60/217 (27%), Positives = 88/217 (40%), Gaps = 47/217 (21%)

Query: 164 QQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA-------------QPQG 210
           QQ T+S TT   GQ+  +  Q         +  + Q +Q+  A             QP  
Sbjct: 350 QQNTNSLTT-SSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTS 408

Query: 211 QAQQAQSGTGQTMQVMQQIITNTGE--IQQIPVQLNAG----QLQYIRLAQPVS-GTQVV 263
           QAQ  Q  T QT+  +Q    N  +  +Q + +QLN G    Q Q +  +  V+  T  V
Sbjct: 409 QAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQVTWQTFQV 468

Query: 264 QG-----QIQTLATNAQQITQTEVQQ---GQQQFS--------QFTDGQLYQIQQVTMPA 307
           QG      +Q   T AQQIT T VQ    GQ              + GQL  +Q VT+ +
Sbjct: 469 QGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNLQTVTVNS 528

Query: 308 ----------GQDLAQPMFIQSANQPSDGQAPQVTGD 334
                     G++   P  I+   +  D +  Q++GD
Sbjct: 529 IDSAGIQLHPGENADSPADIRIKEEEPDPEEWQLSGD 565


>gi|4506495 regulatory factor X3 isoform a [Homo sapiens]
          Length = 707

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 7/97 (7%)

Query: 211 QAQQAQSGTGQTM----QVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQV--VQ 264
           Q  +  S TG T+     V  Q    T  +QQ+PVQ    Q+Q ++  Q V   QV  V+
Sbjct: 2   QTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYVE 61

Query: 265 GQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQ 301
           G   T+ TN    T T      Q +SQ T G  +  Q
Sbjct: 62  GS-DTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQ 97


>gi|19743884 regulatory factor X3 isoform b [Homo sapiens]
          Length = 749

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 32/97 (32%), Positives = 43/97 (44%), Gaps = 7/97 (7%)

Query: 211 QAQQAQSGTGQTM----QVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQV--VQ 264
           Q  +  S TG T+     V  Q    T  +QQ+PVQ    Q+Q ++  Q V   QV  V+
Sbjct: 2   QTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYVE 61

Query: 265 GQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQ 301
           G   T+ TN    T T      Q +SQ T G  +  Q
Sbjct: 62  GS-DTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQ 97


>gi|4758010 clock [Homo sapiens]
          Length = 846

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 53/178 (29%), Positives = 70/178 (39%), Gaps = 34/178 (19%)

Query: 164 QQTTSSTTTIQPGQIIIAQPQQ----GQT----------TPVTMQVGEGQQVQIVQAQPQ 209
           QQT  ST+T     ++    QQ     QT          T V  Q   G  VQI  + PQ
Sbjct: 625 QQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAPLYNTMVISQPAAGSMVQIPSSMPQ 684

Query: 210 GQAQQAQSGT-GQTMQVM----QQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQ 264
              Q A   T  Q  Q+     QQ++T   ++   PV   A     + +   +   QVV 
Sbjct: 685 NSTQSAAVTTFTQDRQIRFSQGQQLVT---KLVTAPVACGA-----VMVPSTMLMGQVVT 736

Query: 265 GQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQP--MFIQSA 320
               T AT  QQ     V Q QQQ S     Q  Q+  V  P+   L QP   F+Q++
Sbjct: 737 A-YPTFATQQQQSQTLSVTQQQQQQS----SQEQQLTSVQQPSQAQLTQPPQQFLQTS 789



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 50/176 (28%), Positives = 64/176 (36%), Gaps = 36/176 (20%)

Query: 144 YYFTLAQQPTA---VQVQGQ--QQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEG 198
           Y   +  QP A   VQ+     Q   Q+ + TT  Q  QI  +Q QQ  T  VT  V  G
Sbjct: 662 YNTMVISQPAAGSMVQIPSSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVACG 721

Query: 199 QQV--------QIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQY 250
             +        Q+V A P    QQ QS   QT+ V QQ    + + QQ+       Q Q 
Sbjct: 722 AVMVPSTMLMGQVVTAYPTFATQQQQS---QTLSVTQQQQQQSSQEQQLTSVQQPSQAQ- 777

Query: 251 IRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMP 306
             L QP                  QQ  QT         +Q      + +QQ T P
Sbjct: 778 --LTQP-----------------PQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFP 814



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 1/79 (1%)

Query: 151 QPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQ-PQQGQTTPVTMQVGEGQQVQIVQAQPQ 209
           Q  +V  Q QQQ  Q    T+  QP Q  + Q PQQ   T   +      Q+ +  A P 
Sbjct: 749 QTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPL 808

Query: 210 GQAQQAQSGTGQTMQVMQQ 228
            Q+   QS   Q     QQ
Sbjct: 809 QQSTFPQSHHQQHQSQQQQ 827


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 42/144 (29%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 123 LKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQ-----QGQQTTSSTTTIQPGQ 177
           + P + Q+ ++Q V   + +Q    L QQ  AV +Q QQ     + QQ       +Q  Q
Sbjct: 99  ITPQQMQQILQQQVLSPQQLQ---ALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155

Query: 178 IIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQ 237
               Q QQ Q      Q  + QQ Q  Q Q Q Q QQ   G     Q  QQ        Q
Sbjct: 156 Q--QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 213

Query: 238 QIPVQLNAGQLQYIRLAQPVSGTQ 261
           Q+  Q    Q+Q ++  Q +   Q
Sbjct: 214 QLVFQQQLLQMQQLQQQQHLLSLQ 237



 Score = 35.8 bits (81), Expect = 0.055
 Identities = 44/181 (24%), Positives = 66/181 (36%), Gaps = 7/181 (3%)

Query: 147 TLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQA 206
           TL+ Q  A    G+  G  T+S  +T++     +   QQ Q      Q+   QQ   +++
Sbjct: 22  TLSSQLDAGSRDGRSSGD-TSSEVSTVE-----LLHLQQQQALQAARQLLLQQQTSGLKS 75

Query: 207 QPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQ 266
                 Q+          +  Q+IT   ++QQI  Q      Q   L Q      + Q Q
Sbjct: 76  PKSSDKQRPLQVPVSVAMMTPQVITPQ-QMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ 134

Query: 267 IQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQDLAQPMFIQSANQPSDG 326
           +Q      Q+    ++ Q QQQ  Q    Q  Q QQ      Q   Q    Q   Q   G
Sbjct: 135 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 194

Query: 327 Q 327
           +
Sbjct: 195 K 195



 Score = 28.9 bits (63), Expect = 6.7
 Identities = 47/175 (26%), Positives = 61/175 (34%), Gaps = 23/175 (13%)

Query: 150 QQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQ--------- 200
           Q+P  V V       Q  +     Q  Q  +  PQQ Q      Q    QQ         
Sbjct: 82  QRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKK 141

Query: 201 ------VQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLA 254
                 +Q++Q Q Q Q QQ Q    Q  Q  QQ        QQ   Q    Q Q     
Sbjct: 142 QQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQHPG 194

Query: 255 QPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQIQQVTMPAGQ 309
           +     Q  Q Q Q LA   Q + Q ++ Q QQ   Q     L +   +++P GQ
Sbjct: 195 KQAKEQQQQQQQQQQLAAQ-QLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQ 248


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.128    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,415,228
Number of Sequences: 37866
Number of extensions: 485260
Number of successful extensions: 2417
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 1852
Number of HSP's gapped (non-prelim): 387
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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