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Search of human proteins with 21361709
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361709 regulation of nuclear pre-mRNA domain containing 1A
[Homo sapiens]
(312 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361709 regulation of nuclear pre-mRNA domain containing 1A ... 613 e-176
gi|11034845 Regulation of nuclear pre-mRNA domain containing 1B ... 412 e-115
gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ... 119 3e-27
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap... 46 5e-05
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 43 3e-04
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 43 3e-04
gi|62460633 RNA-binding motif protein 16 [Homo sapiens] 42 7e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.003
gi|93204881 Rab interacting lysosomal protein [Homo sapiens] 40 0.003
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 40 0.003
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 39 0.005
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 39 0.005
gi|195947367 golgi autoantigen, golgin subfamily a, 8B [Homo sap... 39 0.006
gi|31083099 golgi autoantigen, golgin subfamily a, 8A [Homo sapi... 39 0.006
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 38 0.013
gi|38044112 restin isoform b [Homo sapiens] 37 0.023
gi|4506751 restin isoform a [Homo sapiens] 37 0.023
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 36 0.050
gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo ... 35 0.086
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 35 0.086
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 35 0.11
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i... 34 0.15
gi|71061468 centromere protein E [Homo sapiens] 34 0.15
gi|55770834 centromere protein F [Homo sapiens] 34 0.15
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 34 0.19
gi|100814339 coiled-coil domain containing 146 [Homo sapiens] 33 0.25
gi|15431310 keratin 14 [Homo sapiens] 33 0.33
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens] 33 0.33
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens] 33 0.33
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens] 33 0.33
>gi|21361709 regulation of nuclear pre-mRNA domain containing 1A
[Homo sapiens]
Length = 312
Score = 613 bits (1582), Expect = e-176
Identities = 312/312 (100%), Positives = 312/312 (100%)
Query: 1 MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFL 60
MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFL
Sbjct: 1 MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFL 60
Query: 61 YLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYEND 120
YLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYEND
Sbjct: 61 YLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYEND 120
Query: 121 VLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGD 180
VLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGD
Sbjct: 121 VLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGD 180
Query: 181 AAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQL 240
AAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQL
Sbjct: 181 AAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQL 240
Query: 241 TRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHM 300
TRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHM
Sbjct: 241 TRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHM 300
Query: 301 HLPFAGDIYSED 312
HLPFAGDIYSED
Sbjct: 301 HLPFAGDIYSED 312
>gi|11034845 Regulation of nuclear pre-mRNA domain containing 1B
[Homo sapiens]
Length = 326
Score = 412 bits (1060), Expect = e-115
Identities = 213/326 (65%), Positives = 262/326 (80%), Gaps = 14/326 (4%)
Query: 1 MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFL 60
MS+FSE+ALEKKLSELSNSQQSVQTLSLWLIHHRKH+ PIV+VW RELRKAK NRKLTFL
Sbjct: 1 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL 60
Query: 61 YLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYEND 120
YLANDVIQNSKRKGPEFT++F V+V+AF HV+ E DE CKK L R+L+IW+ERSVY +
Sbjct: 61 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE 120
Query: 121 VLEQLKQALYGDKKPR----------KRTYEQIKVDENENCSSLGSPSEPPQ----TLDL 166
++QLK ++ K P KRT++QI+ +E+++ SP +P T +L
Sbjct: 121 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL 180
Query: 167 VRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADY 226
++ALQDLENAASGDA V Q+IASLP EVQ+VSLL+KITDKE+ ERLSK V++AC+LLA+Y
Sbjct: 181 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY 240
Query: 227 NGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSL 286
NGRLAAE++DR+QL RML ++ + QK+ L+EKE KLEEYK+KLARV+ VRKEL+S IQSL
Sbjct: 241 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL 300
Query: 287 PDLSRLPNVTGSHMHLPFAGDIYSED 312
PDLS LPNVTG LP AGD++S D
Sbjct: 301 PDLSLLPNVTGGLAPLPSAGDLFSTD 326
>gi|183396804 Regulation of nuclear pre-mRNA domain containing 2
[Homo sapiens]
Length = 1461
Score = 119 bits (298), Expect = 3e-27
Identities = 84/300 (28%), Positives = 143/300 (47%), Gaps = 15/300 (5%)
Query: 6 EAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLAND 65
E++L++K ++N+ +S+Q LS W I ++KH IV W + LR++ +L YLAND
Sbjct: 24 ESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLAND 83
Query: 66 VIQNSKRKGP-EFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQ 124
VIQN KRK F + FA V+ EA V D S K + R+ IWE+R+VY +++
Sbjct: 84 VIQNCKRKNAIIFRESFADVLPEAAALVK---DPSVSKSVERIFKIWEDRNVYPEEMIVA 140
Query: 125 LKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLD-----------LVRALQDL 173
L++AL K +K+ E + N+ + + P L L+ L
Sbjct: 141 LREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLY 200
Query: 174 ENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAE 233
+ + ++++++ V+V L + DK G++ SK E+A L ++ L +
Sbjct: 201 KRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQ 260
Query: 234 IDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLP 293
+ + LT L + + E + YK RV+ ++K+L +LPD P
Sbjct: 261 VKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESP 320
>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo
sapiens]
Length = 1555
Score = 45.8 bits (107), Expect = 5e-05
Identities = 31/117 (26%), Positives = 60/117 (51%), Gaps = 8/117 (6%)
Query: 10 EKKLSELS-NSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQ 68
+ L +L+ NS+ + L++ + ++ IV++ E + KA + KL +YL + +++
Sbjct: 23 QSSLEDLTFNSKPHINMLTILAEENLPFAKEIVSLIEAQTAKAPSSEKLPVMYLMDSIVK 82
Query: 69 NSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEE----RSVYENDV 121
N G E+ F +V F V + DE+ +K L ++ S W+E + +Y DV
Sbjct: 83 NV---GREYLTAFTKNLVATFICVFEKVDENTRKSLFKLRSTWDEIFPLKKLYALDV 136
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 43.1 bits (100), Expect = 3e-04
Identities = 30/130 (23%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 40 IVTVWERELRKAKPNRKLTFLYLANDVIQNSKRK--------GPEFTKDFAPVIVEAFKH 91
+V + E+ ++K KP K+ LY+ + +++ S+ + GP F+K+ I F++
Sbjct: 43 VVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKN----ITATFQY 98
Query: 92 VSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENC 151
+ E K + RVL++W++ V++ ++++ L G E + +E
Sbjct: 99 LYLCPSED-KSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAP-VAENVTNNEGSPP 156
Query: 152 SSLGSPSEPP 161
+ SEPP
Sbjct: 157 PPVKVSSEPP 166
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 43.1 bits (100), Expect = 3e-04
Identities = 30/130 (23%), Positives = 62/130 (47%), Gaps = 14/130 (10%)
Query: 40 IVTVWERELRKAKPNRKLTFLYLANDVIQNSKRK--------GPEFTKDFAPVIVEAFKH 91
+V + E+ ++K KP K+ LY+ + +++ S+ + GP F+K+ I F++
Sbjct: 43 VVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKN----ITATFQY 98
Query: 92 VSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENC 151
+ E K + RVL++W++ V++ ++++ L G E + +E
Sbjct: 99 LYLCPSED-KSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAP-VAENVTNNEGSPP 156
Query: 152 SSLGSPSEPP 161
+ SEPP
Sbjct: 157 PPVKVSSEPP 166
>gi|62460633 RNA-binding motif protein 16 [Homo sapiens]
Length = 1271
Score = 42.0 bits (97), Expect = 7e-04
Identities = 32/142 (22%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 35 KHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRK-GPE---FTKDFAPVIVEAFK 90
K + +V E+ ++K KP K+ LY+ + +++ S+ + G E F F+ I+ F+
Sbjct: 38 KFYKHVVQSVEKFIQKCKPEYKVPGLYVIDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQ 97
Query: 91 HVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENEN 150
++ + K + RVL++W++ +V+++++++ L G P N
Sbjct: 98 NLYRCPGDD-KSKIVRVLNLWQKNNVFKSEIIQPLLDMAAGIPPPVVTPVLASTTTAMSN 156
Query: 151 CSSLGSPSEPPQTLDLVRALQD 172
+ G+P P ++V+ L D
Sbjct: 157 --TPGTPVTPVTPANVVQGLPD 176
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 40.0 bits (92), Expect = 0.003
Identities = 59/278 (21%), Positives = 121/278 (43%), Gaps = 28/278 (10%)
Query: 10 EKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQN 69
E+K +++ Q+ +Q W HRK +R E ++A+ RKL + Q
Sbjct: 1555 EEKEQQVTEEQRHIQEEHKWARIHRKRAR-------AEKKRAQEERKLA--QEEEKLAQE 1605
Query: 70 SKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQAL 129
++ E K + +A+ ++ + E + G+ + EE + L Q + L
Sbjct: 1606 ERQLAQEERK-----LAQAYVKITQDDREMAQAE-GK-FAQKEETLAQRGEKLSQEAEKL 1658
Query: 130 YGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTL--DLVRALQDLENAASGDAAVHQRI 187
+K + +E++ +E + G +E L + Q +N + + Q +
Sbjct: 1659 AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL 1718
Query: 188 ASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLA-- 245
L +++E+S ++ ++E G K+VE+ LA+ LA + + + LA
Sbjct: 1719 EELEWDMEELSWKEEELNQEEG----KLVEEK-KKLAEEEEALAWQREKLSEEETKLAQE 1773
Query: 246 -DFLRCQKEALAEKEHKLEEYKRKLA--RVSLVRKELR 280
+ L +KE LA+ + K+ E + +L R L+ K+++
Sbjct: 1774 EELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMK 1811
Score = 30.4 bits (67), Expect = 2.1
Identities = 47/234 (20%), Positives = 93/234 (39%), Gaps = 33/234 (14%)
Query: 92 VSSETDESCKKHLGRVLSIWEERSVYENDVLEQLK-------QALYGDKKPRKRTYEQIK 144
++ E + +KH +L EE + E +V+ LK +A GDK P+++ Q+
Sbjct: 2160 MTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDK-PKEKFSSQVD 2218
Query: 145 ---------------VDENENCSSLGSPSEPPQTLDLVRALQDL-ENAASGDAAVHQRIA 188
+DE E SL S E + + R +++ E
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK 2278
Query: 189 SLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFL 248
+ E +E K KE + ++ E+ ++++ ++ ++ ++ + +
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVD 2338
Query: 249 RCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHL 302
R ++ EK+ KL+E + RK LR R + L L +P+ G + L
Sbjct: 2339 REKEILKKEKQFKLQEQR---------RKSLRGRERVLSILRGVPHGKGRAIRL 2383
>gi|93204881 Rab interacting lysosomal protein [Homo sapiens]
Length = 401
Score = 39.7 bits (91), Expect = 0.003
Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 13/121 (10%)
Query: 166 LVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLAD 225
+VRAL+ LE AA G A ++++ P E QE+ L + ++ E + E+ +L
Sbjct: 58 VVRALELLEQAAVGPAPDSLQVSAQPAE-QELRRLREENERLRRELRAGPQEERALL--- 113
Query: 226 YNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQS 285
R E+ DR++ D LR L ++ + E + +L R+ LV ELR ++ +
Sbjct: 114 ---RQLKEVTDRQR------DELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAA 164
Query: 286 L 286
+
Sbjct: 165 M 165
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 39.7 bits (91), Expect = 0.003
Identities = 19/77 (24%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 56 KLTFLYLANDVIQNSKRK-GPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEER 114
+L +YL NDV+ + +RK E V+V + +E ++ + R+L +WE+
Sbjct: 211 RLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKN 270
Query: 115 SVYENDVLEQLKQALYG 131
+++ +++QL+ G
Sbjct: 271 GYFDDSIIQQLQSPALG 287
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 39.3 bits (90), Expect = 0.005
Identities = 59/267 (22%), Positives = 117/267 (43%), Gaps = 52/267 (19%)
Query: 45 ERELRKAKPNRKLTFLYLANDVIQN-----SKRKG---PEFTKDFAPVIVEAFKHVSSET 96
E E+ K + N L + N V +N +K K P F K+ A +IV+ + ++ +T
Sbjct: 1576 EIEIVKEEFNEHLEVVDKINQVCKNLQFYLNKMKTFEEPPFEKE-ANIIVDRWLDINEKT 1634
Query: 97 DESCKKHLGRVLSIWEERSVYENDVLEQLKQALYG------DKKPRKRTYEQIKVDENE- 149
E ++LGR L++W++ +N + E ++AL ++ R+R E+++V E +
Sbjct: 1635 -EDYYENLGRALALWDKLFNLKNVIDEWTEKALQKMELHQLTEEDRERLKEELQVHEQKT 1693
Query: 150 --------NCSSLGSPSEPPQTLDLVRA-----LQDLENAASGDAAVHQRIASLPVEVQE 196
L SE P L ++ + ++ ++ +G++ H ++ E++E
Sbjct: 1694 SEFSRRVAEIQFLLQSSEIPLELQVMESSILNKMEHVQKCLTGESNCH-ALSGSTAELRE 1752
Query: 197 ------------VSLLDKITDKESGERLSKMVE---------DACMLLADYNGRLAAEID 235
SLL ++ +S E +K+ E + +LL + G L E+
Sbjct: 1753 DLDQAKTQIGMTESLLKALSPSDSLEIFTKLEEIQQQILQQKHSMILLENQIGCLTPELS 1812
Query: 236 DRKQLTRMLADFLRCQKEALAEKEHKL 262
+ K+ ++D +K L + KL
Sbjct: 1813 ELKKQYESVSDLFNTKKSVLQDHFSKL 1839
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 39.3 bits (90), Expect = 0.005
Identities = 59/267 (22%), Positives = 117/267 (43%), Gaps = 52/267 (19%)
Query: 45 ERELRKAKPNRKLTFLYLANDVIQN-----SKRKG---PEFTKDFAPVIVEAFKHVSSET 96
E E+ K + N L + N V +N +K K P F K+ A +IV+ + ++ +T
Sbjct: 1576 EIEIVKEEFNEHLEVVDKINQVCKNLQFYLNKMKTFEEPPFEKE-ANIIVDRWLDINEKT 1634
Query: 97 DESCKKHLGRVLSIWEERSVYENDVLEQLKQALYG------DKKPRKRTYEQIKVDENE- 149
E ++LGR L++W++ +N + E ++AL ++ R+R E+++V E +
Sbjct: 1635 -EDYYENLGRALALWDKLFNLKNVIDEWTEKALQKMELHQLTEEDRERLKEELQVHEQKT 1693
Query: 150 --------NCSSLGSPSEPPQTLDLVRA-----LQDLENAASGDAAVHQRIASLPVEVQE 196
L SE P L ++ + ++ ++ +G++ H ++ E++E
Sbjct: 1694 SEFSRRVAEIQFLLQSSEIPLELQVMESSILNKMEHVQKCLTGESNCH-ALSGSTAELRE 1752
Query: 197 ------------VSLLDKITDKESGERLSKMVE---------DACMLLADYNGRLAAEID 235
SLL ++ +S E +K+ E + +LL + G L E+
Sbjct: 1753 DLDQAKTQIGMTESLLKALSPSDSLEIFTKLEEIQQQILQQKHSMILLENQIGCLTPELS 1812
Query: 236 DRKQLTRMLADFLRCQKEALAEKEHKL 262
+ K+ ++D +K L + KL
Sbjct: 1813 ELKKQYESVSDLFNTKKSVLQDHFSKL 1839
>gi|195947367 golgi autoantigen, golgin subfamily a, 8B [Homo
sapiens]
Length = 603
Score = 38.9 bits (89), Expect = 0.006
Identities = 55/299 (18%), Positives = 127/299 (42%), Gaps = 26/299 (8%)
Query: 5 SEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWEREL--RKAKPNRKLTFLYL 62
+E LE ++ L+ ++ + T ++H KHS ++L R + ++++ L
Sbjct: 119 AERELEGQIQRLNTEKKKLNTD----LYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEW 174
Query: 63 ANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVL 122
+ + +++K P+ + +++ S K H+ ++ +E + +
Sbjct: 175 SLCAVAATQKKKPDGFSSRSKALLKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYA 234
Query: 123 EQLK-QALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDA 181
EQ+K + ++ RK + E + E + + + +L R+L L+N +
Sbjct: 235 EQIKGERAQWQQRMRKMSQEVCTLKEEKK-------HDTHRVEELERSLSRLKNQMAEPL 287
Query: 182 AVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLT 241
S VE+Q+ L K ++ +GE +++ + C+ L + +K+
Sbjct: 288 PPDAPAVSSEVELQD---LRKELERVAGELQAQVENNQCISLLNRG---------QKERL 335
Query: 242 RMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHM 300
R + L+ Q+E L E+E +L++ + + ++ E +S +Q + L G M
Sbjct: 336 REQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKELQEKLGQVM 394
Score = 30.0 bits (66), Expect = 2.8
Identities = 20/70 (28%), Positives = 31/70 (44%)
Query: 231 AAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLS 290
AA ++ R L D ++ K+ + EH+LEE K+ +EL +IQ L
Sbjct: 75 AAVLNSRSIKISRLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEK 134
Query: 291 RLPNVTGSHM 300
+ N HM
Sbjct: 135 KKLNTDLYHM 144
>gi|31083099 golgi autoantigen, golgin subfamily a, 8A [Homo
sapiens]
Length = 603
Score = 38.9 bits (89), Expect = 0.006
Identities = 55/299 (18%), Positives = 127/299 (42%), Gaps = 26/299 (8%)
Query: 5 SEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWEREL--RKAKPNRKLTFLYL 62
+E LE ++ L+ ++ + T ++H KHS ++L R + ++++ L
Sbjct: 119 AERELEGQIQRLNTEKKKLNTD----LYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEW 174
Query: 63 ANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVL 122
+ + +++K P+ + +++ S K H+ ++ +E + +
Sbjct: 175 SLCAVAATQKKKPDGFSSRSKALLKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYA 234
Query: 123 EQLK-QALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDA 181
EQ+K + ++ RK + E + E + + + +L R+L L+N +
Sbjct: 235 EQIKGERAQWQQRMRKMSQEVCTLKEEKK-------HDTHRVEELERSLSRLKNQMAEPL 287
Query: 182 AVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLT 241
S VE+Q+ L K ++ +GE +++ + C+ L + +K+
Sbjct: 288 PPDAPAVSSEVELQD---LRKELERVAGELQAQVENNQCISLLNRG---------QKERL 335
Query: 242 RMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHM 300
R + L+ Q+E L E+E +L++ + + ++ E +S +Q + L G M
Sbjct: 336 REQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKELQEKLGQVM 394
Score = 30.0 bits (66), Expect = 2.8
Identities = 20/70 (28%), Positives = 31/70 (44%)
Query: 231 AAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLS 290
AA ++ R L D ++ K+ + EH+LEE K+ +EL +IQ L
Sbjct: 75 AAVLNSRSIKISRLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEK 134
Query: 291 RLPNVTGSHM 300
+ N HM
Sbjct: 135 KKLNTDLYHM 144
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 37.7 bits (86), Expect = 0.013
Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 14/120 (11%)
Query: 50 KAKPNRKLTFLYLANDVIQNSKRK--------GPEFTKDFAPVIVEAFKHVSSETDESCK 101
K KP K+ LY+ + +++ S+ + GP F+K+ I F+++ E K
Sbjct: 38 KCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKN----ITATFQYLYLCPSED-K 92
Query: 102 KHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPP 161
+ RVL++W++ V++ ++++ L G E + +E + SEPP
Sbjct: 93 SKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAP-VAENVTNNEGSPPPPVKVSSEPP 151
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 37.0 bits (84), Expect = 0.023
Identities = 50/254 (19%), Positives = 100/254 (39%), Gaps = 42/254 (16%)
Query: 43 VWERELRKAKPNRKLTFLYL--------ANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSS 94
V E +L+ K N +FL A Q + +K E K+ + + K + +
Sbjct: 912 VEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMET 971
Query: 95 ETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSL 154
++ C++ R E ++L+ L++ L T +++K EN L
Sbjct: 972 SHNQ-CQELKARYERATSETKTKHEEILQNLQKTLLD-------TEDKLKGAREENSGLL 1023
Query: 155 GSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSK 214
E + D +A Q E+A + +++++T KE E L+
Sbjct: 1024 QELEELRKQADKAKAAQTAEDA--------------------MQIMEQMT-KEKTETLAS 1062
Query: 215 MVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSL 274
+ ED N +L E+D K+ + L KE L + K+EE+++++ +
Sbjct: 1063 L-EDT----KQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1117
Query: 275 VRKELRSRIQSLPD 288
+ ++ +L +
Sbjct: 1118 AAAQKSQQLSALQE 1131
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 37.0 bits (84), Expect = 0.023
Identities = 50/254 (19%), Positives = 100/254 (39%), Gaps = 42/254 (16%)
Query: 43 VWERELRKAKPNRKLTFLYL--------ANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSS 94
V E +L+ K N +FL A Q + +K E K+ + + K + +
Sbjct: 947 VEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMET 1006
Query: 95 ETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSL 154
++ C++ R E ++L+ L++ L T +++K EN L
Sbjct: 1007 SHNQ-CQELKARYERATSETKTKHEEILQNLQKTLLD-------TEDKLKGAREENSGLL 1058
Query: 155 GSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSK 214
E + D +A Q E+A + +++++T KE E L+
Sbjct: 1059 QELEELRKQADKAKAAQTAEDA--------------------MQIMEQMT-KEKTETLAS 1097
Query: 215 MVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSL 274
+ ED N +L E+D K+ + L KE L + K+EE+++++ +
Sbjct: 1098 L-EDT----KQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1152
Query: 275 VRKELRSRIQSLPD 288
+ ++ +L +
Sbjct: 1153 AAAQKSQQLSALQE 1166
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 35.8 bits (81), Expect = 0.050
Identities = 52/215 (24%), Positives = 90/215 (41%), Gaps = 20/215 (9%)
Query: 87 EAFKHVSSETDESCKKHLGRVLSIWEER--SVYENDVLEQLKQALYGDKKPRKRTYEQIK 144
+ K V+ + + + + H ++ + EER S+ E D + +AL +K + +Q
Sbjct: 565 QQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQL 624
Query: 145 VDENENCSSLGSPSEPPQT--LDLVRALQDL----ENAASGDAAVHQRIASLPVEVQEVS 198
NE S + Q +L R +++L E A ++A L E+Q S
Sbjct: 625 QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL--ELQLRS 682
Query: 199 LLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFL----RCQKEA 254
K T+KE + +++ L + +++ K R AD L RC E
Sbjct: 683 EQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEK---RRAADALEEQQRCISEL 739
Query: 255 LAEKEHKLEEYKR---KLARVSLVRKELRSRIQSL 286
AE +E++KR +L RK L +R+Q L
Sbjct: 740 KAETRSLVEQHKRERKELEEERAGRKGLEARLQQL 774
>gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo
sapiens]
Length = 449
Score = 35.0 bits (79), Expect = 0.086
Identities = 41/203 (20%), Positives = 81/203 (39%), Gaps = 20/203 (9%)
Query: 112 EERSVYENDVLEQLKQALYGDKK-------PRKRTYEQIKVDENENCSSLGSPSEPPQTL 164
+E V ND +++ + + DK+ P E + ENE +G+ L
Sbjct: 125 DESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE-EEIGNLELAWDML 183
Query: 165 DLVRAL---QDLENAASGDAAVHQRIASLPVE-------VQEVSLLDKITDK--ESGERL 212
DL + + Q+ + A A H ++ + VE V+E + ++ E+ +RL
Sbjct: 184 DLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRL 243
Query: 213 SKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARV 272
L YN + + + ++ + + E + E E EYK+++ +
Sbjct: 244 LAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEEL 303
Query: 273 SLVRKELRSRIQSLPDLSRLPNV 295
+ E+R +I+ + R NV
Sbjct: 304 KELLPEIREKIEDAKESQRSGNV 326
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 35.0 bits (79), Expect = 0.086
Identities = 68/330 (20%), Positives = 124/330 (37%), Gaps = 63/330 (19%)
Query: 1 MSAFSEAALEKK--LSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLT 58
++A E LEK+ +SEL + + + L +H +V+ ER LR R
Sbjct: 110 LNACREQLLEKEEEISELKAERNNTRLLL-------EHLECLVSRHERSLRMTVVKR--- 159
Query: 59 FLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKH---VSSETDESCKKHLGRVLSIWEERS 115
Q G + + F+H + + E + L RV ++ EE +
Sbjct: 160 ---------QAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELA 210
Query: 116 VYENDVLEQLKQALYGDKKPRKRT----YEQIKVDE-----NENCSSLGSPSEPPQTLDL 166
+++ +Q ++ +K E ++ E +E S GS +T +
Sbjct: 211 AANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQI 270
Query: 167 VRALQDLENAASGDAAVHQRIASLPVEVQEV------SLLDKITDKESGERLSKMVEDAC 220
V + LE A + +R+A+L V EV + D I +E + + + +A
Sbjct: 271 VELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAM 330
Query: 221 ML------------------------LADYNGRLAAEIDDRKQLTRMLADFLRCQKEALA 256
+ D N +L E+ +++ + R + + R +E L
Sbjct: 331 AQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLE 390
Query: 257 EKEHKLEEYKRKLARVSLVRKELRSRIQSL 286
E KL++ RK + V EL RI +L
Sbjct: 391 LAEQKLQQTMRKAETLPEVEAELAQRIAAL 420
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 34.7 bits (78), Expect = 0.11
Identities = 67/318 (21%), Positives = 130/318 (40%), Gaps = 54/318 (16%)
Query: 9 LEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRK-AKPNRKLTFLYLANDVI 67
+++ LSEL+ + +QT + L + IV+ R + + +L +
Sbjct: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKA 1326
Query: 68 QNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLS-----IWEERSVYENDVL 122
+N+ + ++ ++ E + E ++ K L R LS + + R+ YE D +
Sbjct: 1327 KNALAHALQSSRHDCDLLREQY-----EEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1381
Query: 123 EQLKQALYGDKKPRKRTYEQIKVDE--NENCSSLGSPSEPPQTLDLVRALQDLENAASGD 180
++ ++ KK +R + + E N C+SL + Q ++ + D+E A S
Sbjct: 1382 QRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQG-EVEDLMVDVERANSLA 1440
Query: 181 AAVHQRI------------------ASLPVEVQEV---------------SLLDKI-TDK 206
AA+ ++ A L ++E LD++ T K
Sbjct: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
Query: 207 ESGERLSKMVEDACMLLADYNGRLAAEID-DRKQLTRMLADFLRCQKEALAEKEHKLEEY 265
+ L + + D +A+ NG+ E++ RKQ+ AD + AL E E LE
Sbjct: 1501 RENKNLEQEIADLTEQIAE-NGKTIHELEKSRKQIELEKADI----QLALEEAEAALEHE 1555
Query: 266 KRKLARVSLVRKELRSRI 283
+ K+ R+ L +++S I
Sbjct: 1556 EAKILRIQLELTQVKSEI 1573
Score = 32.0 bits (71), Expect = 0.72
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 15/147 (10%)
Query: 169 ALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNG 228
A+Q E + QR+ +V+ V+ +K +RL VED + + N
Sbjct: 1380 AIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTK-QRLQGEVEDLMVDVERANS 1438
Query: 229 RLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEE--------------YKRKLARVSL 274
AA ++ ++LA++ +E+ AE E L+E Y+ L ++
Sbjct: 1439 LAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLET 1498
Query: 275 VRKELRSRIQSLPDLSRLPNVTGSHMH 301
V++E ++ Q + DL+ G +H
Sbjct: 1499 VKRENKNLEQEIADLTEQIAENGKTIH 1525
>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
isoform 1 [Homo sapiens]
Length = 721
Score = 34.3 bits (77), Expect = 0.15
Identities = 46/243 (18%), Positives = 99/243 (40%), Gaps = 32/243 (13%)
Query: 69 NSKRKGPEFTKDFAPVIVEAFKH--------VSSETDESCKKHLGRVLSIWEERSVYEND 120
+S R P FT D IV + + VS+ S G V+S ++ S+ +
Sbjct: 231 SSARSSPGFTNDDTASIVSSDRASRGRRESVVSAADYFSRSNRRGSVVSEVDDISIPDLS 290
Query: 121 VLEQLKQALYGDK--KPRKRTYEQIKVDENENCSSLGSPS-----EPPQTLDLVRALQDL 173
L++ Y + +P R + N S GS +P +L +R + DL
Sbjct: 291 SLDEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDL 350
Query: 174 ENAAS--------GDAAVHQRIASLPVEVQEVSLLDKITDKESG------ERLSKMVEDA 219
++ G + + ++ + + ++ + + D E + L ++E+
Sbjct: 351 KDQIQDVEGRYMQGLKELKESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQ 410
Query: 220 CMLLADY---NGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVR 276
+A++ N + E++ +K + +L + KE L +++ +EE +R ++ +
Sbjct: 411 EEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQRDELIEEKQRMQQKIDTMT 470
Query: 277 KEL 279
KE+
Sbjct: 471 KEV 473
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 34.3 bits (77), Expect = 0.15
Identities = 45/182 (24%), Positives = 82/182 (45%), Gaps = 17/182 (9%)
Query: 120 DVLEQLKQALYGDKKPRKRTYEQIKVDENENCS-SLGSPSEPPQTLDL-------VRALQ 171
D EQL+ AL K+ + T +K +E S +L +T D + Q
Sbjct: 961 DTQEQLRNALESLKQ-HQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQ 1019
Query: 172 DLENAASGDAAVHQRIASLPVEVQEVSLLDKITDK-ESGERLSKMVEDACMLLADYNGRL 230
DLE A + + + Q+ + I +K E + L ++ + L D +
Sbjct: 1020 DLE--AKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENI 1077
Query: 231 AAEIDDRKQLTRMLADFLRCQKEALA-EKEHKLE---EYKRKLARVSLVRKELRSRIQSL 286
I+++++L R+L D L+ Q+E +A EK H ++ E R R++ V ++L+ + Q L
Sbjct: 1078 EMTIENQEEL-RLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQL 1136
Query: 287 PD 288
+
Sbjct: 1137 QE 1138
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 34.3 bits (77), Expect = 0.15
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 30/159 (18%)
Query: 165 DLVRALQDLENAASGDAAVHQRIASLP---------VEVQEVSLLDKITDKESG--ERLS 213
+LVR + A++ A+ Q++ L E SL KI +KE E LS
Sbjct: 342 ELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELS 401
Query: 214 KM------VEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKR 267
+ ++ C+ + RL E+ K + +L L + E+ LEE+K+
Sbjct: 402 RQQRSFQTLDQECIQM---KARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQ 458
Query: 268 KLARV-------SLVRKELRSRIQSLPDLSRLPNVTGSH 299
KL R + ELR +S+ ++ + N+ SH
Sbjct: 459 KLCRAEQAFQASQIKENELR---RSMEEMKKENNLLKSH 494
Score = 28.9 bits (63), Expect = 6.1
Identities = 40/179 (22%), Positives = 67/179 (37%), Gaps = 38/179 (21%)
Query: 122 LEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDA 181
+E+L+ + D+K + E++K E EN S L +++LE
Sbjct: 2121 IEKLRVRIEADEKKQLHIAEKLKERERENDS-------------LKDKVENLE------- 2160
Query: 182 AVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLT 241
R + E QE+ +LD K E L +E+ L + L +++ LT
Sbjct: 2161 ----RELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLT 2216
Query: 242 RMLAD----------FLRCQKEALAEKEHK----LEEYKRKLARVSLVRKELRSRIQSL 286
+ + + L K L EKE EE K + + KEL + +L
Sbjct: 2217 KQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL 2275
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 33.9 bits (76), Expect = 0.19
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 14/181 (7%)
Query: 92 VSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENC 151
+ +E ES K+L + +S EE + +K+ + + RK E+I+ + E
Sbjct: 1949 IKNELLESEMKNLKKCVSELEEEKQ------QLVKEKTKVESEIRKEYLEKIQGAQKEP- 2001
Query: 152 SSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQ-RIASLPVEVQEVSLLDKITDKE--- 207
G+ S + +L++ Q D +Q +I++L V+ + + + K+
Sbjct: 2002 ---GNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEI 2058
Query: 208 SGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKR 267
+ E L++ VE A+ D + + R+LAD L+ +KE + KE + K+
Sbjct: 2059 TKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ 2118
Query: 268 K 268
K
Sbjct: 2119 K 2119
Score = 31.2 bits (69), Expect = 1.2
Identities = 49/235 (20%), Positives = 94/235 (40%), Gaps = 50/235 (21%)
Query: 87 EAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVD 146
E+ K + DE ++ L + EE+ + E +++ AL +K + T +I+V
Sbjct: 2110 ESVKSQMKQKDEDLERRLEQA----EEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVT 2165
Query: 147 ENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEV--------- 197
N+ + ++ + ++L++ + AA + ++SL + V
Sbjct: 2166 LNK------------KDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWER 2213
Query: 198 SLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRK------------------- 238
D I KE RL ED C +L D +++ +++ K
Sbjct: 2214 KFSDAIQSKEEEIRLK---EDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQT 2270
Query: 239 --QLTRMLADFLRCQ-KEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLS 290
QL + + D L+ + KE L++ E Y ++ + EL+S L DLS
Sbjct: 2271 EVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLS 2325
>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
Length = 955
Score = 33.5 bits (75), Expect = 0.25
Identities = 31/115 (26%), Positives = 59/115 (51%), Gaps = 8/115 (6%)
Query: 168 RALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYN 227
R L ++E D+ + +R L EV EV+ + K E SK+VE LA+ N
Sbjct: 387 RLLLEMEAIPKDDSTLSERRRELHKEV-EVAKRNLAQQKIISEMESKLVEQQ---LAEEN 442
Query: 228 GRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSR 282
+L E ++ K+L + + LR + + EKE K +++ + + + + KE++++
Sbjct: 443 -KLLKEQENMKEL---VVNLLRMTQIKIDEKEQKSKDFLKAQQKYTNIVKEMKAK 493
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 33.1 bits (74), Expect = 0.33
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 16/128 (12%)
Query: 164 LDLVRALQDLENAASGDAAVHQRI---ASLPVEVQEVSLLDKITDKESGERLSKMVEDAC 220
LD VRAL++ A+ D V R P E+++ S K + + L+ V++A
Sbjct: 130 LDKVRALEE----ANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATVDNAN 185
Query: 221 MLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELR 280
+LL N RLAA+ K T + LR EA + +R L ++L R +L
Sbjct: 186 VLLQIDNARLAADDFRTKYETEL---NLRMSVEA------DINGLRRVLDELTLARADLE 236
Query: 281 SRIQSLPD 288
+I+SL +
Sbjct: 237 MQIESLKE 244
>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
Length = 541
Score = 33.1 bits (74), Expect = 0.33
Identities = 24/120 (20%), Positives = 57/120 (47%), Gaps = 12/120 (10%)
Query: 171 QDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACML-------- 222
Q+L++ S H+ + L +V+E + + E + L K+ E+ C+L
Sbjct: 59 QELKSLRSQLDVTHKEVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQ 118
Query: 223 ---LADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKEL 279
+ ++ G +DR ++ R+ A ++++L ++ +L Y+++++ + RK L
Sbjct: 119 KKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRL-IYQQQVSSLEAQRKAL 177
>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
Length = 703
Score = 33.1 bits (74), Expect = 0.33
Identities = 24/120 (20%), Positives = 57/120 (47%), Gaps = 12/120 (10%)
Query: 171 QDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACML-------- 222
Q+L++ S H+ + L +V+E + + E + L K+ E+ C+L
Sbjct: 59 QELKSLRSQLDVTHKEVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQ 118
Query: 223 ---LADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKEL 279
+ ++ G +DR ++ R+ A ++++L ++ +L Y+++++ + RK L
Sbjct: 119 KKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRL-IYQQQVSSLEAQRKAL 177
>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
Length = 475
Score = 33.1 bits (74), Expect = 0.33
Identities = 24/120 (20%), Positives = 57/120 (47%), Gaps = 12/120 (10%)
Query: 171 QDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACML-------- 222
Q+L++ S H+ + L +V+E + + E + L K+ E+ C+L
Sbjct: 59 QELKSLRSQLDVTHKEVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQ 118
Query: 223 ---LADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKEL 279
+ ++ G +DR ++ R+ A ++++L ++ +L Y+++++ + RK L
Sbjct: 119 KKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRL-IYQQQVSSLEAQRKAL 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,395,833
Number of Sequences: 37866
Number of extensions: 480809
Number of successful extensions: 2067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 125
Number of HSP's that attempted gapping in prelim test: 1920
Number of HSP's gapped (non-prelim): 253
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.