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Search of human proteins with 21361499
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo
sapiens]
(574 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens] 1203 0.0
gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens] 306 4e-83
gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens] 170 4e-42
gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens] 147 2e-35
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 55 1e-07
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 55 1e-07
gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo ... 55 2e-07
gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo ... 55 2e-07
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 53 7e-07
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 52 2e-06
gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo sa... 51 3e-06
gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo sa... 51 3e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 49 1e-05
gi|38788260 bromodomain PHD finger transcription factor isoform ... 45 2e-04
gi|38788274 bromodomain PHD finger transcription factor isoform ... 45 2e-04
gi|31543392 peroxisome proliferator-activated receptor gamma, co... 44 4e-04
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 44 4e-04
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H... 44 4e-04
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 44 5e-04
gi|24431933 reticulon 4 isoform B [Homo sapiens] 43 7e-04
gi|47519490 reticulon 4 isoform D [Homo sapiens] 43 7e-04
gi|24431935 reticulon 4 isoform A [Homo sapiens] 43 7e-04
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 43 7e-04
gi|19115964 phospholipase C delta 3 [Homo sapiens] 43 9e-04
gi|164419758 bromodomain containing 2 [Homo sapiens] 43 9e-04
gi|4826806 bromodomain containing 2 [Homo sapiens] 43 9e-04
gi|24850133 protein inhibitor of activated STAT, 4 [Homo sapiens] 43 9e-04
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 43 9e-04
gi|6912492 mitogen-activated protein kinase 8 interacting protei... 43 9e-04
gi|7706537 mitogen-activated protein kinase 8 interacting protei... 43 9e-04
>gi|21361499 SUMO1/sentrin/SMT3 specific protease 3 [Homo sapiens]
Length = 574
Score = 1203 bits (3112), Expect = 0.0
Identities = 574/574 (100%), Positives = 574/574 (100%)
Query: 1 MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPA 60
MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPA
Sbjct: 1 MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPA 60
Query: 61 RRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRK 120
RRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRK
Sbjct: 61 RRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRK 120
Query: 121 TCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP 180
TCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP
Sbjct: 121 TCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVP 180
Query: 181 SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGL 240
SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGL
Sbjct: 181 SPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGL 240
Query: 241 LSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPG 300
LSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPG
Sbjct: 241 LSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPG 300
Query: 301 EKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV 360
EKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV
Sbjct: 301 EKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLV 360
Query: 361 LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPE 420
LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPE
Sbjct: 361 LQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPE 420
Query: 421 KVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITY 480
KVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITY
Sbjct: 421 KVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITY 480
Query: 481 FDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYC 540
FDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYC
Sbjct: 481 FDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYC 540
Query: 541 KHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV 574
KHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV
Sbjct: 541 KHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV 574
>gi|159032029 SUMO1/sentrin specific peptidase 5 [Homo sapiens]
Length = 755
Score = 306 bits (783), Expect = 4e-83
Identities = 148/274 (54%), Positives = 202/274 (73%), Gaps = 6/274 (2%)
Query: 300 GEKAGQHSPLREEHVT-CVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKG 358
G+ + + SP+ +E ++ C+ LDE ++ YGSL+PLS EV+ +L+D+F ++FS +RK
Sbjct: 485 GKNSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFS--NRKP 542
Query: 359 LVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTV 418
+ + I +Y+ FR+ Y +H+L MDDL TL GQNWLNDQV+NMYG+L+MD V
Sbjct: 543 FINREITNYRARHQKC---NFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAV 599
Query: 419 PEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTI 478
P+KVHFFNSFF+ +L TKGY+GVKRWTK VD+F K LLLIPIHLEVHWSLI+V + R I
Sbjct: 600 PDKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRII 659
Query: 479 TYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQ 538
+++DSQ + C ++I KYL EA +K+R +F QGW+ + +Q NDSDCG FVLQ
Sbjct: 660 SFYDSQGIHFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQ 719
Query: 539 YCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKL 572
YCK LAL QPF F+Q+DMP++R++IYKELC C+L
Sbjct: 720 YCKCLALEQPFQFSQEDMPRVRKRIYKELCECRL 753
>gi|7657550 sentrin/SUMO-specific protease 1 [Homo sapiens]
Length = 643
Score = 170 bits (430), Expect = 4e-42
Identities = 83/194 (42%), Positives = 124/194 (63%), Gaps = 6/194 (3%)
Query: 385 RHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEK----VHFFNSFFYDKLRTKGYDG 440
R +T D+ TL NWLND+++N Y +++M+ EK VH FN+FF+ KL+T GY
Sbjct: 449 RLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQA 508
Query: 441 VKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQ 500
VKRWTK VD+F+ ++LL+PIHL VHW L VD R++ ITY+DS +N + + +YL+
Sbjct: 509 VKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLK 568
Query: 501 AEAVKKDRLDFH-QGWKGYFKMN-VARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPK 558
E++ K R +F GW+ + K + + +Q N SDCG F +Y + +P +FTQQ MP
Sbjct: 569 QESIDKKRKEFDTNGWQLFSKKSQIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPY 628
Query: 559 LRRQIYKELCHCKL 572
R+++ E+ H KL
Sbjct: 629 FRKRMVWEILHRKL 642
>gi|54607091 SUMO1/sentrin/SMT3 specific protease 2 [Homo sapiens]
Length = 589
Score = 147 bits (372), Expect = 2e-35
Identities = 78/228 (34%), Positives = 132/228 (57%), Gaps = 19/228 (8%)
Query: 360 VLQLIQSYQRMPGNAMVRG-----FRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLV 414
+L+L + ++ NA+ G A+K + T D+ TL +WLND+V+N Y +L+
Sbjct: 365 LLELTEDMEKEISNALGHGPQDEILSSAFKLRI-TRGDIQTLKNYHWLNDEVINFYMNLL 423
Query: 415 MDTVPEK----VHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLIS 470
++ ++ +H F++FFY KL++ GY VKRWTK V++F +E++L+PIH +VHWSL+
Sbjct: 424 VERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVV 483
Query: 471 VDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDF------HQGWKGYFKMNVA 524
+D+R++ + Y DS R + + +YLQ E+ K D H K + +
Sbjct: 484 IDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPH---EIP 540
Query: 525 RQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKL 572
+Q N SDCG F +Y +++ +P +FTQ MP R+++ E+ H +L
Sbjct: 541 QQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQL 588
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 55.5 bits (132), Expect = 1e-07
Identities = 85/332 (25%), Positives = 119/332 (35%), Gaps = 59/332 (17%)
Query: 16 PGPGIPPAYSSPRRERLRWPPPPKP-RLKSGGGFGPD---------PGSGTTVPARRL-- 63
P G P + S R R + PPPP P RL S G P+ P G T P RR
Sbjct: 767 PARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLS 826
Query: 64 -------PVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLP-PRWSQLGTSQRPRPSR 115
P P+ AS+ EEEE E + LP L QRP+P+
Sbjct: 827 EPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAG 886
Query: 116 PTHRKT---------------------CSQRR--RRAMRAFRMLLYSKSTSLTFHWKLWG 152
P R+T C +R + A+ AF + + + G
Sbjct: 887 PPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPG 946
Query: 153 RHRGRRRGLAHPKNHLSPQQGGATPQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGS 212
L P+ P QG TP PSP + P PP P GL + +
Sbjct: 947 -ESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQ---PPVPPCPGPGLESSAASRWNGETE 1002
Query: 213 PPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPE-GERSLAPPDASILIS 271
PP ++ G PK P+ ++CT G + P G R + PP
Sbjct: 1003 PPAAPAALLKVPGAGTAPK-PVS-----VACTQLAFSGPKLAPRLGPRPVPPPRP----E 1052
Query: 272 NVCSIGDHVAQELFQGSDLGMAEEAERPGEKA 303
+ ++G AQ+ + + +A A R EK+
Sbjct: 1053 STGTVGPGQAQQRLEQTSSSLA-AALRAAEKS 1083
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 55.5 bits (132), Expect = 1e-07
Identities = 85/332 (25%), Positives = 119/332 (35%), Gaps = 59/332 (17%)
Query: 16 PGPGIPPAYSSPRRERLRWPPPPKP-RLKSGGGFGPD---------PGSGTTVPARRL-- 63
P G P + S R R + PPPP P RL S G P+ P G T P RR
Sbjct: 849 PARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLS 908
Query: 64 -------PVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLP-PRWSQLGTSQRPRPSR 115
P P+ AS+ EEEE E + LP L QRP+P+
Sbjct: 909 EPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAG 968
Query: 116 PTHRKT---------------------CSQRR--RRAMRAFRMLLYSKSTSLTFHWKLWG 152
P R+T C +R + A+ AF + + + G
Sbjct: 969 PPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPG 1028
Query: 153 RHRGRRRGLAHPKNHLSPQQGGATPQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGS 212
L P+ P QG TP PSP + P PP P GL + +
Sbjct: 1029 -ESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQ---PPVPPCPGPGLESSAASRWNGETE 1084
Query: 213 PPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPE-GERSLAPPDASILIS 271
PP ++ G PK P+ ++CT G + P G R + PP
Sbjct: 1085 PPAAPAALLKVPGAGTAPK-PVS-----VACTQLAFSGPKLAPRLGPRPVPPPRP----E 1134
Query: 272 NVCSIGDHVAQELFQGSDLGMAEEAERPGEKA 303
+ ++G AQ+ + + +A A R EK+
Sbjct: 1135 STGTVGPGQAQQRLEQTSSSLA-AALRAAEKS 1165
>gi|156105703 SUMO1/sentrin specific peptidase 6 isoform 2 [Homo
sapiens]
Length = 1105
Score = 54.7 bits (130), Expect = 2e-07
Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 20/104 (19%)
Query: 388 LTMDDLGTLYGQNWLNDQVMNMYGD-LVMDTVP----EKVHFFNSFFYDKL--------- 433
+T +DL L +LND +++ Y LV++ + +++H F+SFFY +L
Sbjct: 661 VTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHE 720
Query: 434 ------RTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISV 471
+ K + VK WT++VDIF K+ + +P++ HW L V
Sbjct: 721 TTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVV 764
Score = 34.3 bits (77), Expect = 0.32
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 466 WSLISVDVRRRTITYFDSQRTLNR-RCPKHIAKYLQAE-AVKK-DRLDFHQGWKGYFKMN 522
W L ++ I DS R +R K + +YL+ E VKK + F +
Sbjct: 954 WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1013
Query: 523 VARQNNDSDCGAFVLQYCKHLALSQPFSF 551
V +QNN SDCG +VLQY + + SF
Sbjct: 1014 VPQQNNFSDCGVYVLQYVESFFENPILSF 1042
>gi|156105701 SUMO1/sentrin specific peptidase 6 isoform 1 [Homo
sapiens]
Length = 1112
Score = 54.7 bits (130), Expect = 2e-07
Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 20/104 (19%)
Query: 388 LTMDDLGTLYGQNWLNDQVMNMYGD-LVMDTVP----EKVHFFNSFFYDKL--------- 433
+T +DL L +LND +++ Y LV++ + +++H F+SFFY +L
Sbjct: 668 VTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHE 727
Query: 434 ------RTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISV 471
+ K + VK WT++VDIF K+ + +P++ HW L V
Sbjct: 728 TTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVV 771
Score = 34.3 bits (77), Expect = 0.32
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 466 WSLISVDVRRRTITYFDSQRTLNR-RCPKHIAKYLQAE-AVKK-DRLDFHQGWKGYFKMN 522
W L ++ I DS R +R K + +YL+ E VKK + F +
Sbjct: 961 WHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPK 1020
Query: 523 VARQNNDSDCGAFVLQYCKHLALSQPFSF 551
V +QNN SDCG +VLQY + + SF
Sbjct: 1021 VPQQNNFSDCGVYVLQYVESFFENPILSF 1049
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 53.1 bits (126), Expect = 7e-07
Identities = 73/250 (29%), Positives = 104/250 (41%), Gaps = 40/250 (16%)
Query: 76 EEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRM 135
EEEEEEEEEE+E+EEEE AA + LG PR + S R + +
Sbjct: 754 EEEEEEEEEEEEEEEEEEAAAAV-----ALGEVLGPRSGSSSEGSERSTDRSQEGAPSTL 808
Query: 136 LLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVPSPCCRFDSP---RGP 192
L + S RGR + L P++G T + SP SP
Sbjct: 809 LADDQKES-----------RGR---ASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELA 854
Query: 193 PPPRLGLLGALMAEDGVRGSPPVPSGPPME--EDG-----LRWTPKSPLDPDSGLLSCTL 245
P P LG L AL + P P+G ++ E G L+ PK P P +GL + T+
Sbjct: 855 PDPDLGTLAALTPQH----ERPQPTGSQLDVSEPGTLSSVLKSEPKPP-GPGAGLGAGTV 909
Query: 246 PNGFGG---QSGP--EGERSLAPPDASILISNVCSIGDHVAQELFQ-GSDLGMAEEAERP 299
G GG S P + ER+ ++ + S G + E F G +LG+ ++
Sbjct: 910 TTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGG 969
Query: 300 GEKAGQHSPL 309
+ G +PL
Sbjct: 970 AVEEGARAPL 979
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/88 (39%), Positives = 44/88 (50%), Gaps = 17/88 (19%)
Query: 13 PEPPGPGIPPAYSSPRRERL--------RWPPPPKPRLKSGGGFGPDPGSGTTVPARRLP 64
P PP P PPA +PR + + PPP P K + P +G+ P+
Sbjct: 209 PPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQK----YDPFEPTGSN-PSSSAG 263
Query: 65 VPRPSFDASASEEEEEEEEEEDEDEEEE 92
P P + EEEEEEEEEE+EDEEEE
Sbjct: 264 TPSPEEE----EEEEEEEEEEEEDEEEE 287
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/105 (36%), Positives = 43/105 (40%), Gaps = 19/105 (18%)
Query: 7 GTGSWGPEPP--------GPGIPPAYSSPRRERLRWPP----PPKPRLKSGGGFGPDPGS 54
GTG GP PP P P+ SSP PP PP PR F P +
Sbjct: 178 GTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEA 237
Query: 55 GTTVPARRLPV-------PRPSFDASASEEEEEEEEEEDEDEEEE 92
+ PA PS A EEEEEEEE+E+EEEE
Sbjct: 238 YSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEE 282
Score = 39.7 bits (91), Expect = 0.008
Identities = 52/174 (29%), Positives = 65/174 (37%), Gaps = 39/174 (22%)
Query: 74 ASEEEEEEEEEEDEDEEEE------------VAAWRLPP-----------------RWSQ 104
A EEEEEEEEEE+E+EEEE AA P R SQ
Sbjct: 1021 AEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQ 1080
Query: 105 LGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHP 164
L T P P C+ A+ A +L + +L K + + L+H
Sbjct: 1081 LPTLPPPMPWNLPAGVDCTTSGVLALTA--LLFKMEEANLASRAKAQELIQATNQILSHR 1138
Query: 165 KNHLSPQQGGATPQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSG 218
K P G TP P P S PP P LL + G +PP P+G
Sbjct: 1139 K---PPSSLGMTP-APVP----TSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTG 1184
Score = 32.7 bits (73), Expect = 0.93
Identities = 51/238 (21%), Positives = 78/238 (32%), Gaps = 40/238 (16%)
Query: 13 PEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDA 72
P P PP RRER R K S G P P P P +D+
Sbjct: 505 PAPAAAAGPPTRKKSRRERKR-SGEAKEAASSSSGTQPAP-----------PAPASPWDS 552
Query: 73 SASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRA 132
+ + + R R ++ + R + R ++RRR R+
Sbjct: 553 KKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRS 612
Query: 133 FRMLLYSKSTSLTFHWKLWGRHR---GRRRGLAHPKNHLSPQQGGATPQVPSP------- 182
+ S+S + + G+HR G ++ ++ + G + + P+P
Sbjct: 613 ASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGS 672
Query: 183 --CCRFDS-PRGPPPP--------------RLGLLGALMAEDGVRGSPPVPSGPPMEE 223
C DS RG PP R +G L D RG P P+ P E
Sbjct: 673 TSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSD-PRGPSPAPASSPKRE 729
>gi|116174736 sentrin/SUMO-specific protease 7 isoform 2 [Homo
sapiens]
Length = 985
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 21/102 (20%)
Query: 388 LTMDDLGTLYGQNWLNDQVMNMYGDLVM-----DTVPEKVHFFNSFFYDKLRTKG----- 437
+T +DL L +LND +++ Y ++ D + E+ H F+SFFY L K
Sbjct: 697 VTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTE 756
Query: 438 -----------YDGVKRWTKNVDIFNKELLLIPIHLEVHWSL 468
+ V+ WT++++IFNK+ + +P++ HW L
Sbjct: 757 DNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYL 798
>gi|116174746 sentrin/SUMO-specific protease 7 isoform 1 [Homo
sapiens]
Length = 1050
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 21/102 (20%)
Query: 388 LTMDDLGTLYGQNWLNDQVMNMYGDLVM-----DTVPEKVHFFNSFFYDKLRTKG----- 437
+T +DL L +LND +++ Y ++ D + E+ H F+SFFY L K
Sbjct: 762 VTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTE 821
Query: 438 -----------YDGVKRWTKNVDIFNKELLLIPIHLEVHWSL 468
+ V+ WT++++IFNK+ + +P++ HW L
Sbjct: 822 DNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYL 863
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 49.3 bits (116), Expect = 1e-05
Identities = 35/82 (42%), Positives = 39/82 (47%), Gaps = 11/82 (13%)
Query: 12 GPEPPGPGIPPAYSSPRRERLRWPPPPK-PRLKSGGGFGPDPGSGTTVPARRLPVPRPSF 70
GP PP P PP P + PPP P GGG P TV + S
Sbjct: 837 GPLPPPPPPPPPVPGP----VTLPPPQLVPEGTPGGGGPPALEEDLTV------ININSS 886
Query: 71 DASASEEEEEEEEEEDEDEEEE 92
D EEEEEEEEEE+E+EEEE
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEE 908
Score = 34.3 bits (77), Expect = 0.32
Identities = 21/60 (35%), Positives = 26/60 (43%)
Query: 16 PGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASAS 75
P P PP SP R PP P P + S GP P +G A +P RP +A+
Sbjct: 648 PAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTAN 707
Score = 33.9 bits (76), Expect = 0.42
Identities = 17/41 (41%), Positives = 23/41 (56%)
Query: 76 EEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRP 116
EEEEEEE+EE+E+E EEV ++ P P+ P
Sbjct: 943 EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLP 983
Score = 33.5 bits (75), Expect = 0.54
Identities = 17/27 (62%), Positives = 20/27 (74%), Gaps = 3/27 (11%)
Query: 70 FDASASEEE---EEEEEEEDEDEEEEV 93
F+ EEE EEEEEEEDE+EEEE+
Sbjct: 931 FEEEFEEEEGELEEEEEEEDEEEEEEL 957
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/91 (36%), Positives = 40/91 (43%), Gaps = 17/91 (18%)
Query: 7 GTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSG-----TTVPAR 61
G+ S PP P PP+ S+P R GGG G G G A
Sbjct: 70 GSSSRRKPPPPPPAPPSTSAPGRG------------GRGGGGGRTGGGGGGGHLARTTAA 117
Query: 62 RLPVPRPSFDASASEEEEEEEEEEDEDEEEE 92
R V + +D SEEEEEEE+ E+EEEE
Sbjct: 118 RRAVNKVVYDDHESEEEEEEEDMVSEEEEEE 148
Score = 30.4 bits (67), Expect = 4.6
Identities = 46/168 (27%), Positives = 56/168 (33%), Gaps = 39/168 (23%)
Query: 155 RGRRRGLAHPKNHLSPQQGGATPQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGS-- 212
RGRR PK +P P P P PPPP G +G L + RGS
Sbjct: 2 RGRRG--RPPKQPAAPAAERCAPAPPPP---------PPPPTSGPIGGLRSRH--RGSSR 48
Query: 213 --------PPVP----SGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERS 260
P S P R P P P S T G GG+ G G
Sbjct: 49 GRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPS-----TSAPGRGGRGGGGGRTG 103
Query: 261 -------LAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGE 301
LA A+ N DH ++E + D+ EE E G+
Sbjct: 104 GGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGD 151
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/91 (36%), Positives = 40/91 (43%), Gaps = 17/91 (18%)
Query: 7 GTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSG-----TTVPAR 61
G+ S PP P PP+ S+P R GGG G G G A
Sbjct: 70 GSSSRRKPPPPPPAPPSTSAPGRG------------GRGGGGGRTGGGGGGGHLARTTAA 117
Query: 62 RLPVPRPSFDASASEEEEEEEEEEDEDEEEE 92
R V + +D SEEEEEEE+ E+EEEE
Sbjct: 118 RRAVNKVVYDDHESEEEEEEEDMVSEEEEEE 148
Score = 30.4 bits (67), Expect = 4.6
Identities = 46/168 (27%), Positives = 56/168 (33%), Gaps = 39/168 (23%)
Query: 155 RGRRRGLAHPKNHLSPQQGGATPQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGS-- 212
RGRR PK +P P P P PPPP G +G L + RGS
Sbjct: 2 RGRRG--RPPKQPAAPAAERCAPAPPPP---------PPPPTSGPIGGLRSRH--RGSSR 48
Query: 213 --------PPVP----SGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERS 260
P S P R P P P S T G GG+ G G
Sbjct: 49 GRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPS-----TSAPGRGGRGGGGGRTG 103
Query: 261 -------LAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGE 301
LA A+ N DH ++E + D+ EE E G+
Sbjct: 104 GGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGD 151
>gi|31543392 peroxisome proliferator-activated receptor gamma,
coactivator 1 beta [Homo sapiens]
Length = 1023
Score = 43.9 bits (102), Expect = 4e-04
Identities = 87/340 (25%), Positives = 115/340 (33%), Gaps = 95/340 (27%)
Query: 13 PEPP-----GPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPR 67
P PP PG P + E +R PK GP P + V R
Sbjct: 375 PRPPKDSQASPGRPSSV-----EEVRIAASPKST-------GPRPSLRPLRLEVKREVRR 422
Query: 68 PSFDASASEEEEEEEEEEDEDEEEEVAAW--RLPPR---WSQLGTSQRPRPSRPTHRKTC 122
P+ EE+EEEEEEE+E+E+EE W + P R W++LG R C
Sbjct: 423 PARLQQQEEEDEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLG--------RKLESSVC 474
Query: 123 SQRRRRAMR---------AFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQ-- 171
RR R + A L+ S+ L + R L P + S Q
Sbjct: 475 PVRRSRRLNPELGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQ 534
Query: 172 ---QGGATPQVPSPC---CRFDSPRGPPPPRLG-------LLGALMAEDGVRGS------ 212
+G P + SPC C D P P+L L+ AL D G
Sbjct: 535 QLLRGPQIPALESPCESGCG-DMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQT 593
Query: 213 -------------PPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGER 259
P P P EED + K L + LS P G ++ P
Sbjct: 594 LTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKEIA-LSLPSPEGLSLKATPGAAH 652
Query: 260 SLAP--PDASILISNV------------------CSIGDH 279
L P+ S L+S++ CS GDH
Sbjct: 653 KLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDH 692
Score = 35.8 bits (81), Expect = 0.11
Identities = 24/51 (47%), Positives = 32/51 (62%), Gaps = 4/51 (7%)
Query: 76 EEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRR 126
EEEEEE EEE+ED+EEE + + P S Q P PS+ +R+ CS+ R
Sbjct: 807 EEEEEEGEEEEEDDEEEDSG--VSPTCSDHCPYQSP-PSK-ANRQLCSRSR 853
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 43.9 bits (102), Expect = 4e-04
Identities = 36/113 (31%), Positives = 40/113 (35%), Gaps = 14/113 (12%)
Query: 9 GSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRP 68
G+ P+ PG G PPA PPPP PR + PDP S P L P P
Sbjct: 767 GAAAPQYPGRGPPPAPP---------PPPPPPRAPADPAASPDPPSAVASPGSGLSSPGP 817
Query: 69 SFDASASEEEEEEEEE-----EDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRP 116
S E E E EEE V R PP G + P P
Sbjct: 818 KPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGP 870
Score = 40.4 bits (93), Expect = 0.004
Identities = 77/281 (27%), Positives = 97/281 (34%), Gaps = 56/281 (19%)
Query: 11 WGPEPPGPGIPPAYSSPRR------ERLRWP--PPPKP---RLKSGGGF---GPDP---G 53
W P PG P A +P E P P P+P + + G F G DP G
Sbjct: 586 WDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRG 645
Query: 54 SGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRP 113
+G T+ V A EEEEEEEE E+ S LG R
Sbjct: 646 AGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDS-----------SSLGGGPSRRG 694
Query: 114 SRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPK---NHLSP 170
P CS+ A L + ++ WG H G HP + L
Sbjct: 695 PLPC--PLCSREG-----ACSCLPLERGDAVAG----WGGHPAL--GCPHPPEDDSSLRA 741
Query: 171 QQGGATPQVPSPCCRFDSPRGPPPPRLG-LLGALMAEDGVRGSPPVPSGPPMEEDGLRWT 229
++G +P P PP L L+GA + RG PP P PP
Sbjct: 742 ERGSLADLPMAP------PASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADP 795
Query: 230 PKSPLDPDSGLLS----CTLPNGFGGQSGPEGERSLAPPDA 266
SP DP S + S + P G SG E E +P A
Sbjct: 796 AASP-DPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGA 835
Score = 34.7 bits (78), Expect = 0.24
Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 30/80 (37%)
Query: 16 PGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASAS 75
PGPG PRR PP +G G G+G PA
Sbjct: 1273 PGPG-------PRR-------PPWEGADAGAAGGEAGGAGAPGPA--------------- 1303
Query: 76 EEEEEEEEEEDEDEEEEVAA 95
EE+ E+E+EDE+E+EE AA
Sbjct: 1304 -EEDGEDEDEDEEEDEEAAA 1322
>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
sapiens]
Length = 747
Score = 43.9 bits (102), Expect = 4e-04
Identities = 31/77 (40%), Positives = 35/77 (45%), Gaps = 15/77 (19%)
Query: 45 GGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEED-----EDEEEEVAAWRLP 99
GGG GP G A PV EEE+EEEEEED EDE+EE P
Sbjct: 48 GGGAGP----GGACKAEPRPVAASGGGPGGDEEEDEEEEEEDEEALLEDEDEE------P 97
Query: 100 PRWSQLGTSQRPRPSRP 116
P LG + +P P P
Sbjct: 98 PPAQALGQAAQPPPEPP 114
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 43.5 bits (101), Expect = 5e-04
Identities = 70/278 (25%), Positives = 96/278 (34%), Gaps = 49/278 (17%)
Query: 12 GPEPPGPGIPPAYSSPRRERLRWPPPPKPRL----KSGGGFGPDPGSGTTVPARR---LP 64
GP PG G P SSP P PP R+ KS GP P + P P
Sbjct: 952 GPFNPGSGGPLPASSPAS--FDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAP 1009
Query: 65 VPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPR---WSQLGTSQRPRPSRPTHRKT 121
P+P + E E D+ A P W G S P P+H +
Sbjct: 1010 PPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGS 1069
Query: 122 CS----QRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLA-HPKNHLSPQQGGAT 176
+ A+R F++ + S ++ + RGR+ L K PQ+GG
Sbjct: 1070 AGGGGGSSQGPALRYFQLPPRAASAAMYVPAR---SGRGRKGPLVKQTKVEGEPQKGGGL 1126
Query: 177 PQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVP-----------SGPPMEEDG 225
P PSP SP P PP +A + S P+P SG +
Sbjct: 1127 PPAPSP----TSPASPQPP------PAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSS 1176
Query: 226 LRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAP 263
P + +P G G GG S P +++P
Sbjct: 1177 TEAEPPTQPEPTGG--------GGGGGSSPSPAPAMSP 1206
Score = 32.7 bits (73), Expect = 0.93
Identities = 24/69 (34%), Positives = 27/69 (39%), Gaps = 14/69 (20%)
Query: 8 TGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPR 67
+G P GPG+PP SPRR P P PR G +P LP P
Sbjct: 1506 SGRGPPSEDGPGVPPP--SPRRSVP--PSPTSPRASEENG----------LPLLVLPPPA 1551
Query: 68 PSFDASASE 76
PS D E
Sbjct: 1552 PSVDVEDGE 1560
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 43.1 bits (100), Expect = 7e-04
Identities = 23/56 (41%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 64 PVPRPSFD---ASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRP 116
P P+P+F E+EEEEEEEE+EDE+E++ + R G S P P+ P
Sbjct: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAP 72
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 43.1 bits (100), Expect = 7e-04
Identities = 23/56 (41%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 64 PVPRPSFD---ASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRP 116
P P+P+F E+EEEEEEEE+EDE+E++ + R G S P P+ P
Sbjct: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAP 72
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 43.1 bits (100), Expect = 7e-04
Identities = 23/56 (41%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 64 PVPRPSFD---ASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRP 116
P P+P+F E+EEEEEEEE+EDE+E++ + R G S P P+ P
Sbjct: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAP 72
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 43.1 bits (100), Expect = 7e-04
Identities = 26/67 (38%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 50 PDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQ 109
P P + + P PS EEEEEEEEEE E+EEEE + PP S
Sbjct: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP----- 344
Query: 110 RPRPSRP 116
P+P+ P
Sbjct: 345 -PQPASP 350
>gi|19115964 phospholipase C delta 3 [Homo sapiens]
Length = 789
Score = 42.7 bits (99), Expect = 9e-04
Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 27/128 (21%)
Query: 20 IPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEE 79
+ A SP E L P K R+ V ++LP R + S+ EE
Sbjct: 455 VTQALDSPNPEELPSPEQLKGRV--------------LVKGKKLPAARSEDGRALSDREE 500
Query: 80 EEEEEEDEDEEEEVAAWR-----LPPRWSQLGT--------SQRPRPSRPTHRKTCSQRR 126
EEE++E+E+EE E AA R + P S L + P P+ P + S
Sbjct: 501 EEEDDEEEEEEVEAAAQRRLAKQISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSE 560
Query: 127 RRAMRAFR 134
R+A + R
Sbjct: 561 RKAKKLIR 568
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 42.7 bits (99), Expect = 9e-04
Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 14/79 (17%)
Query: 27 PRRERLRWPPPPKPRLKSGG-----------GFGPDPGSGTTVPARRLPVPRPSFDASAS 75
PR R PP PK K+ G GFGP GSGT +P + P+
Sbjct: 576 PRAPR---PPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYD 632
Query: 76 EEEEEEEEEEDEDEEEEVA 94
EEEEE DE+ +++
Sbjct: 633 SEEEEESRPMSYDEKRQLS 651
Score = 37.7 bits (86), Expect = 0.029
Identities = 20/44 (45%), Positives = 24/44 (54%)
Query: 49 GPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEEEE 92
GP P S P S + S+SE EEEEEEDE++EEE
Sbjct: 461 GPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEE 504
Score = 36.6 bits (83), Expect = 0.064
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 16/75 (21%)
Query: 69 SFDASASEEEEEEEEEEDEDEE------EEVAAWRLPPRWSQL--------GTSQRP--R 112
S S+SEEEEEE+EE++E+EE EE A RL QL SQ P +
Sbjct: 485 SSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISK 544
Query: 113 PSRPTHRKTCSQRRR 127
P R +K ++R+
Sbjct: 545 PKRKREKKEKKKKRK 559
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 42.7 bits (99), Expect = 9e-04
Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 14/79 (17%)
Query: 27 PRRERLRWPPPPKPRLKSGG-----------GFGPDPGSGTTVPARRLPVPRPSFDASAS 75
PR R PP PK K+ G GFGP GSGT +P + P+
Sbjct: 576 PRAPR---PPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYD 632
Query: 76 EEEEEEEEEEDEDEEEEVA 94
EEEEE DE+ +++
Sbjct: 633 SEEEEESRPMSYDEKRQLS 651
Score = 37.7 bits (86), Expect = 0.029
Identities = 20/44 (45%), Positives = 24/44 (54%)
Query: 49 GPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEEEE 92
GP P S P S + S+SE EEEEEEDE++EEE
Sbjct: 461 GPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEE 504
Score = 36.6 bits (83), Expect = 0.064
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 16/75 (21%)
Query: 69 SFDASASEEEEEEEEEEDEDEE------EEVAAWRLPPRWSQL--------GTSQRP--R 112
S S+SEEEEEE+EE++E+EE EE A RL QL SQ P +
Sbjct: 485 SSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISK 544
Query: 113 PSRPTHRKTCSQRRR 127
P R +K ++R+
Sbjct: 545 PKRKREKKEKKKKRK 559
>gi|24850133 protein inhibitor of activated STAT, 4 [Homo sapiens]
Length = 510
Score = 42.7 bits (99), Expect = 9e-04
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 10/62 (16%)
Query: 38 PKPRLKSGGGFGPDPGSGTTVPARRLPVPRP-------SFDASASEEEEEEEEEEDEDEE 90
P P + G G G G P + +P + D+S+S E+EEEEEEE+EDE+
Sbjct: 434 PAPSVNGSGALGSTGGGG---PVGSMENGKPGADVVDLTLDSSSSSEDEEEEEEEEEDED 490
Query: 91 EE 92
EE
Sbjct: 491 EE 492
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 42.7 bits (99), Expect = 9e-04
Identities = 22/51 (43%), Positives = 29/51 (56%)
Query: 51 DPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPR 101
+ + ++ P+ V P D EEEEEEEEEE+E+EEEE PPR
Sbjct: 24 EAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPR 74
>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
isoform 1 [Homo sapiens]
Length = 824
Score = 42.7 bits (99), Expect = 9e-04
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 29/112 (25%)
Query: 13 PEPPGPGIPPAYSSPR------------------RERLRWPPPPKPRLKSGGGFGPDPGS 54
P PPG + PA + + E L PPPP P G P P
Sbjct: 377 PRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCL 436
Query: 55 GTTVPAR-----------RLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAA 95
+ P R R P + A+ SEEE+EE++EE+ED E+ +
Sbjct: 437 FLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGS 488
Score = 30.8 bits (68), Expect = 3.5
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 70 FDASASEEEEEEEEEEDEDEEEE 92
F+ EEE++E+EE+E+EEEE
Sbjct: 81 FEMIDDNEEEDDEDEEEEEEEEE 103
>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
isoform 2 [Homo sapiens]
Length = 797
Score = 42.7 bits (99), Expect = 9e-04
Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 29/112 (25%)
Query: 13 PEPPGPGIPPAYSSPR------------------RERLRWPPPPKPRLKSGGGFGPDPGS 54
P PPG + PA + + E L PPPP P G P P
Sbjct: 350 PRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCL 409
Query: 55 GTTVPAR-----------RLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAA 95
+ P R R P + A+ SEEE+EE++EE+ED E+ +
Sbjct: 410 FLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGS 461
Score = 30.8 bits (68), Expect = 3.5
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 70 FDASASEEEEEEEEEEDEDEEEE 92
F+ EEE++E+EE+E+EEEE
Sbjct: 54 FEMIDDNEEEDDEDEEEEEEEEE 76
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,566,293
Number of Sequences: 37866
Number of extensions: 1934118
Number of successful extensions: 31266
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 429
Number of HSP's successfully gapped in prelim test: 568
Number of HSP's that attempted gapping in prelim test: 19038
Number of HSP's gapped (non-prelim): 7766
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.