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Search of human proteins with 21218438
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21218438 GATA zinc finger domain containing 2B [Homo
sapiens]
(593 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21218438 GATA zinc finger domain containing 2B [Homo sapiens] 1165 0.0
gi|164519146 GATA zinc finger domain containing 2A [Homo sapiens] 376 e-104
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 41 0.003
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 41 0.003
gi|56549696 E1A binding protein p400 [Homo sapiens] 40 0.006
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 40 0.006
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 40 0.006
gi|223890225 POU class 6 homeobox 1 [Homo sapiens] 40 0.008
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 40 0.008
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 40 0.008
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 40 0.008
gi|4758472 G protein pathway suppressor 2 [Homo sapiens] 39 0.013
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 38 0.023
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 38 0.023
gi|119943102 CREB binding protein isoform b [Homo sapiens] 38 0.023
gi|119943104 CREB binding protein isoform a [Homo sapiens] 38 0.023
gi|51093863 hypothetical protein LOC64855 isoform 1 [Homo sapiens] 37 0.039
gi|79750824 hypothetical protein LOC64855 isoform 2 [Homo sapiens] 37 0.039
gi|150170729 microtubule associated serine/threonine kinase 3 [H... 37 0.039
gi|38569484 kinesin family member 21A [Homo sapiens] 37 0.067
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens] 36 0.087
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 36 0.087
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 36 0.087
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens] 36 0.087
gi|157266269 GATA like protein-1 [Homo sapiens] 36 0.087
gi|50345997 E1A binding protein p300 [Homo sapiens] 35 0.19
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 35 0.19
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 35 0.19
gi|148612879 polyhomeotic like 3 [Homo sapiens] 35 0.19
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 35 0.19
>gi|21218438 GATA zinc finger domain containing 2B [Homo sapiens]
Length = 593
Score = 1165 bits (3013), Expect = 0.0
Identities = 593/593 (100%), Positives = 593/593 (100%)
Query: 1 MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVP 60
MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVP
Sbjct: 1 MDRMTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVP 60
Query: 61 HELPTKQDGSGVKGYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPERGRLT 120
HELPTKQDGSGVKGYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPERGRLT
Sbjct: 61 HELPTKQDGSGVKGYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPERGRLT 120
Query: 121 PSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARL 180
PSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARL
Sbjct: 121 PSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARL 180
Query: 181 VLLKKLRQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLR 240
VLLKKLRQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLR
Sbjct: 181 VLLKKLRQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLR 240
Query: 241 TLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQP 300
TLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQP
Sbjct: 241 TLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQP 300
Query: 301 QSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQL 360
QSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQL
Sbjct: 301 QSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQL 360
Query: 361 EKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKSCASLLRVEPFVC 420
EKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKSCASLLRVEPFVC
Sbjct: 361 EKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKSCASLLRVEPFVC 420
Query: 421 AQCRTDFTPHWKQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQ 480
AQCRTDFTPHWKQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQ
Sbjct: 421 AQCRTDFTPHWKQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQRLQ 480
Query: 481 QQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRGIPTSARSMLSNFAQAPQLS 540
QQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRGIPTSARSMLSNFAQAPQLS
Sbjct: 481 QQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRGIPTSARSMLSNFAQAPQLS 540
Query: 541 VPGGLLGMPGVNIAYLNTGIGGHKGPSLADRQREYLLDMIPPRSISQSISGQK 593
VPGGLLGMPGVNIAYLNTGIGGHKGPSLADRQREYLLDMIPPRSISQSISGQK
Sbjct: 541 VPGGLLGMPGVNIAYLNTGIGGHKGPSLADRQREYLLDMIPPRSISQSISGQK 593
>gi|164519146 GATA zinc finger domain containing 2A [Homo sapiens]
Length = 633
Score = 376 bits (966), Expect = e-104
Identities = 268/669 (40%), Positives = 357/669 (53%), Gaps = 124/669 (18%)
Query: 4 MTEDALRLNLLKRSLDPADERDDVLAKRLKMEGHEAMERLKMLALLKRKDLANLEVPHEL 63
MTE+A R KR+L+ DDV +K++KME +LA D ++ V
Sbjct: 1 MTEEACRTRSQKRALERDPTEDDVESKKIKMERG-------LLASDLNTD-GDMRV---- 48
Query: 64 PTKQDGSGVKGYEEKLNGNLRPHGDNRTAGRPGKENINDEPVDMSARRSEPERGRLTPSP 123
T + G+G G LR A G+ + D PVDM S+ + R PSP
Sbjct: 49 -TPEPGAG------PTQGLLRATEATAMAMGRGEGLVGDGPVDMRTSHSDMKSERRPPSP 101
Query: 124 DIIVLSDNEA-SSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVL 182
D+IVLSDNE SSPR + LK + E EER+++IKQL++ELRLEEA+LVL
Sbjct: 102 DVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEERERMIKQLKEELRLEEAKLVL 161
Query: 183 LKKLRQSQLQKENVVQKT-------------------------PVVQNAA-----SIVQP 212
LKKLRQSQ+QKE QK P +Q ++ S++ P
Sbjct: 162 LKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPP 221
Query: 213 SPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQ 272
GQQ SKL + +Q V P +R Q IR ++T P +L++ R P+ Q
Sbjct: 222 PLVRGGQQASSKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPS-VQ 280
Query: 273 LQGQRGPPKPGLVRTTT-PNMNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNR 331
+QGQR + GL+R PN + +N + +S+ TS+ ++ P +V
Sbjct: 281 IQGQR-IIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATSAQ------ANSTPTSVAS 333
Query: 332 VSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYM 391
V + SP A+ QAAAKLALRKQLEKTLLEIPPPKPPAP ++FLPSAAN+EFIY+
Sbjct: 334 VVTSAESP------ASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYL 387
Query: 392 VGLEEVVQSVIDSQGK-SCASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCMTSNQK 450
VGLEEVVQ+++++QG+ S A++L EP++CAQC+TDFT W++EK+G I+CE CMT+NQK
Sbjct: 388 VGLEEVVQNLLETQGRMSAATVLSREPYMCAQCKTDFTCRWREEKSGAIMCENCMTTNQK 447
Query: 451 KALKAEHTNRLKNAFVKALQQEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQ 510
KALK EHT+RLK AFVKALQQEQEIEQRL QQ TAPA + T H L+Q
Sbjct: 448 KALKVEHTSRLKAAFVKALQQEQEIEQRLLQQG-----TAPA--QAKAEPTAAPHPVLKQ 500
Query: 511 APQPQ----------------------SSLQRGIPTSARSMLSNFAQAPQLSVPGGLLGM 548
+P+ S L RG T+ R +L F+ +P+L +
Sbjct: 501 VIKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRGVLHTFSPSPKLQNSASATAL 560
Query: 549 -----------------------------PGVNIAYLNTGIGGHKGPSLADRQREYLLDM 579
G +A+++ + HK S DRQREYLLDM
Sbjct: 561 VSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQREYLLDM 620
Query: 580 IPPRSISQS 588
IPPRSI QS
Sbjct: 621 IPPRSIPQS 629
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 41.2 bits (95), Expect = 0.003
Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 21/136 (15%)
Query: 233 GVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPK----------P 282
G+ Q + L+ + I+ T + +M + + AP P + Q+G PK P
Sbjct: 55 GINAQGMTHLEAQNKIKGCTGSL--NMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSP 112
Query: 283 GLVRTTTPNMNPAINYQPQSSSSVPCQRTTS--------SAIYMNLASHIQPGTVNRVSS 334
+ + T+ N N A N P+ SV + TS + + +SH P V V+
Sbjct: 113 AVSKVTSTN-NMAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTP 171
Query: 335 PLPSPSAMTDAANSQA 350
PL + S + AN A
Sbjct: 172 PLFAASGLHANANLSA 187
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 41.2 bits (95), Expect = 0.003
Identities = 67/268 (25%), Positives = 106/268 (39%), Gaps = 46/268 (17%)
Query: 110 RRSEPERGRLTPSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQL 169
+R E E+ +L L D +A R EER +A + +K K +EE++Q ++L
Sbjct: 412 QRREREQRKLQEKEQQRRLEDMQALR-----REEERRQAEREQEYKRKQLEEQRQ-SERL 465
Query: 170 RDELRLEEARL-VLLKKLRQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSR 228
+ +L+ E A L L ++ +Q QLQK+ Q P P + +G++
Sbjct: 466 QRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLP--------GDRKPLYHYGRGMNPADKP 517
Query: 229 PGAQGVEPQNLRTLQGHS-VIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRT 287
A+ VE + Q +S + +S +T P P Q GPP P +
Sbjct: 518 AWAREVEERTRMNKQQNSPLAKSKPGST-----------GPEPPIPQASPGPPGP---LS 563
Query: 288 TTPNMNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAAN 347
TP M + Q S+ Q T + A + ASH P A
Sbjct: 564 QTPPMQRPVEPQEGPHKSLQDQPTRNLAAFP--ASH--------------DPDPAIPAPT 607
Query: 348 SQAAAKLALRKQLEKTLLEIPPPKPPAP 375
+ +A+ A+ +Q E P P P P
Sbjct: 608 ATPSARGAVIRQNSDPTSEGPGPSPNPP 635
Score = 30.4 bits (67), Expect = 4.8
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 7/57 (12%)
Query: 432 KQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQ-RLQQQAALSP 487
+QE K L EQ + ++ L+ EH A++K+LQQ+Q+ +Q + QQQ L P
Sbjct: 448 EQEYKRKQLEEQRQSERLQRQLQQEH------AYLKSLQQQQQQQQLQKQQQQQLLP 498
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 40.0 bits (92), Expect = 0.006
Identities = 53/216 (24%), Positives = 78/216 (36%), Gaps = 28/216 (12%)
Query: 188 QSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSV 247
Q Q Q++ P VQNAAS+ P P G +LP L+ Q V
Sbjct: 528 QRQSQQQYDPSTGPPVQNAASLHTPLPQLPG-----RLPPAGVPTAALSSALQFAQQPQV 582
Query: 248 IRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPA------INYQPQ 301
+ + T +P V P P Q P +P + P ++ PQ
Sbjct: 583 VEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQ 642
Query: 302 SSSSV--------PCQR--TTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAA 351
+S PC R TSS + S PG SSP+ PS+ T+ A S
Sbjct: 643 MVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVT 702
Query: 352 AKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSE 387
++ ++ P KP +P + S +S+
Sbjct: 703 SR-------TPGVVASAPTKPQSPAQNATSSQDSSQ 731
Score = 31.6 bits (70), Expect = 2.2
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 14/102 (13%)
Query: 471 QEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRG------IPT 524
Q Q + QQ L+ TAP ++ T+ R P S LQ P
Sbjct: 2811 QVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQ 2870
Query: 525 SARSMLSNFAQAPQLSVPGGLLGMPGV-----NIAYLNTGIG 561
A+ L A+ P +SVP ++ PGV N+A ++ IG
Sbjct: 2871 PAQVAL---AKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIG 2909
Score = 30.8 bits (68), Expect = 3.7
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 7/69 (10%)
Query: 471 QEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRGIPTSARSML 530
Q ++ + Q Q P+T P V + + T + R P G+PT+A S
Sbjct: 521 QAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPA-------GVPTAALSSA 573
Query: 531 SNFAQAPQL 539
FAQ PQ+
Sbjct: 574 LQFAQQPQV 582
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 40.0 bits (92), Expect = 0.006
Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 12/119 (10%)
Query: 268 PNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSS------------VPCQRTTSSA 315
P PA L+ PP+P T MN +++ P ++ +P ++T
Sbjct: 1335 PPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYREN 1394
Query: 316 IYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPA 374
+ A P R SP P P+ + +A + A+ +L + +L+ PPP+P A
Sbjct: 1395 VGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAA 1453
Score = 34.7 bits (78), Expect = 0.25
Identities = 40/173 (23%), Positives = 61/173 (35%), Gaps = 18/173 (10%)
Query: 205 NAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQR 264
++A I+ +P VGQ L ++P A + Q+ G + TLP +
Sbjct: 537 HSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAV--- 593
Query: 265 VIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVPCQRTTSSAIYMNLASHI 324
A L G +P T P + QP + S+ + + L
Sbjct: 594 ------AMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQA----PPAVSTPLPLGLQ--- 640
Query: 325 QPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPKPPAPLL 377
QP +P P +A A Q + LA EK +L PP P +L
Sbjct: 641 QPQAQQPPQAPTPQAAAPPQATTPQPSPGLA--SSPEKIVLGQPPSATPTAIL 691
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 40.0 bits (92), Expect = 0.006
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 27/200 (13%)
Query: 199 KTPVVQNAAS--IVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSV-IRSATNTT 255
K+P + S + PS Q S++ P A P + G S+ +RS T +
Sbjct: 933 KSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPTGS- 991
Query: 256 LPHMLMSQRVIAPNPAQLQGQR-GPPKPGLVRTTTP--NMNPAINYQPQSSSSVPCQ--R 310
P L S + P+P + + P PG+ + P NMN + ++P R
Sbjct: 992 -PSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPR 1050
Query: 311 TTSSAIYMNLASHIQPGTVNRVSSPLPSPS------AMTDAANSQAAAKLALRKQLEKTL 364
++SSA N S + ++ SSP P+PS MT + + L KT+
Sbjct: 1051 SSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTI 1110
Query: 365 LE-----------IPPPKPP 373
+PPP PP
Sbjct: 1111 ATSDDELLPDRPLLPPPPPP 1130
>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
Length = 301
Score = 39.7 bits (91), Expect = 0.008
Identities = 40/172 (23%), Positives = 69/172 (40%), Gaps = 28/172 (16%)
Query: 196 VVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTT 255
V+ P V N+AS+ P+PA Q Q V PQ L QG + A++
Sbjct: 16 VIGTLPWVVNSASVAAPAPAQSLQ-----------VQAVTPQLLLNAQGQVIATLASSPL 64
Query: 256 LPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVP--CQRTTS 313
P + + + +PA+ + Q P P + + +PA +P +S+ +P C T
Sbjct: 65 PPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETP- 123
Query: 314 SAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLL 365
TV+++ S +PS D N + + A ++ + L
Sbjct: 124 --------------TVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSL 161
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 39.7 bits (91), Expect = 0.008
Identities = 67/273 (24%), Positives = 110/273 (40%), Gaps = 36/273 (13%)
Query: 110 RRSEPERGRLTPSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQL 169
+R E E+ +L L D +A R EER +A + +K K +EE++Q ++L
Sbjct: 412 QRREREQRKLQEKEQQRRLEDMQALR-----REEERRQAEREQEYKRKQLEEQRQ-SERL 465
Query: 170 RDELRLEEARL-VLLKKLRQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSR 228
+ +L+ E A L L ++ +Q QLQK+ Q P P + +G++
Sbjct: 466 QRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLP--------GDRKPLYHYGRGMNPADKP 517
Query: 229 PGAQGVEPQNLRTLQGHS-VIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRT 287
A+ VE + Q +S + +S +T P P Q GPP P +
Sbjct: 518 AWAREVEERTRMNKQQNSPLAKSKPGST-----------GPEPPIPQASPGPPGP---LS 563
Query: 288 TTPNMNPAINYQPQSSSSVPCQRTT----SSAIYMNLASHIQPGTVNRVSSPLP-SPSAM 342
TP M + Q S+ R ++ + + + QP T N + P P
Sbjct: 564 QTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQP-TRNLAAFPASHDPDPA 622
Query: 343 TDAANSQAAAKLALRKQLEKTLLEIPPPKPPAP 375
A + +A+ A+ +Q E P P P P
Sbjct: 623 IPAPTATPSARGAVIRQNSDPTSEGPGPSPNPP 655
Score = 30.4 bits (67), Expect = 4.8
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 7/57 (12%)
Query: 432 KQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQ-RLQQQAALSP 487
+QE K L EQ + ++ L+ EH A++K+LQQ+Q+ +Q + QQQ L P
Sbjct: 448 EQEYKRKQLEEQRQSERLQRQLQQEH------AYLKSLQQQQQQQQLQKQQQQQLLP 498
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 39.7 bits (91), Expect = 0.008
Identities = 67/273 (24%), Positives = 110/273 (40%), Gaps = 36/273 (13%)
Query: 110 RRSEPERGRLTPSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQL 169
+R E E+ +L L D +A R EER +A + +K K +EE++Q ++L
Sbjct: 412 QRREREQRKLQEKEQQRRLEDMQALR-----REEERRQAEREQEYKRKQLEEQRQ-SERL 465
Query: 170 RDELRLEEARL-VLLKKLRQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSR 228
+ +L+ E A L L ++ +Q QLQK+ Q P P + +G++
Sbjct: 466 QRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLP--------GDRKPLYHYGRGMNPADKP 517
Query: 229 PGAQGVEPQNLRTLQGHS-VIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRT 287
A+ VE + Q +S + +S +T P P Q GPP P +
Sbjct: 518 AWAREVEERTRMNKQQNSPLAKSKPGST-----------GPEPPIPQASPGPPGP---LS 563
Query: 288 TTPNMNPAINYQPQSSSSVPCQRTT----SSAIYMNLASHIQPGTVNRVSSPLP-SPSAM 342
TP M + Q S+ R ++ + + + QP T N + P P
Sbjct: 564 QTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQP-TRNLAAFPASHDPDPA 622
Query: 343 TDAANSQAAAKLALRKQLEKTLLEIPPPKPPAP 375
A + +A+ A+ +Q E P P P P
Sbjct: 623 IPAPTATPSARGAVIRQNSDPTSEGPGPSPNPP 655
Score = 30.4 bits (67), Expect = 4.8
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 7/57 (12%)
Query: 432 KQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQ-RLQQQAALSP 487
+QE K L EQ + ++ L+ EH A++K+LQQ+Q+ +Q + QQQ L P
Sbjct: 448 EQEYKRKQLEEQRQSERLQRQLQQEH------AYLKSLQQQQQQQQLQKQQQQQLLP 498
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 39.7 bits (91), Expect = 0.008
Identities = 67/273 (24%), Positives = 110/273 (40%), Gaps = 36/273 (13%)
Query: 110 RRSEPERGRLTPSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLIKQL 169
+R E E+ +L L D +A R EER +A + +K K +EE++Q ++L
Sbjct: 412 QRREREQRKLQEKEQQRRLEDMQALR-----REEERRQAEREQEYKRKQLEEQRQ-SERL 465
Query: 170 RDELRLEEARL-VLLKKLRQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSR 228
+ +L+ E A L L ++ +Q QLQK+ Q P P + +G++
Sbjct: 466 QRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLP--------GDRKPLYHYGRGMNPADKP 517
Query: 229 PGAQGVEPQNLRTLQGHS-VIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRT 287
A+ VE + Q +S + +S +T P P Q GPP P +
Sbjct: 518 AWAREVEERTRMNKQQNSPLAKSKPGST-----------GPEPPIPQASPGPPGP---LS 563
Query: 288 TTPNMNPAINYQPQSSSSVPCQRTT----SSAIYMNLASHIQPGTVNRVSSPLP-SPSAM 342
TP M + Q S+ R ++ + + + QP T N + P P
Sbjct: 564 QTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQP-TRNLAAFPASHDPDPA 622
Query: 343 TDAANSQAAAKLALRKQLEKTLLEIPPPKPPAP 375
A + +A+ A+ +Q E P P P P
Sbjct: 623 IPAPTATPSARGAVIRQNSDPTSEGPGPSPNPP 655
Score = 30.4 bits (67), Expect = 4.8
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 7/57 (12%)
Query: 432 KQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKALQQEQEIEQ-RLQQQAALSP 487
+QE K L EQ + ++ L+ EH A++K+LQQ+Q+ +Q + QQQ L P
Sbjct: 448 EQEYKRKQLEEQRQSERLQRQLQQEH------AYLKSLQQQQQQQQLQKQQQQQLLP 498
>gi|4758472 G protein pathway suppressor 2 [Homo sapiens]
Length = 327
Score = 38.9 bits (89), Expect = 0.013
Identities = 58/236 (24%), Positives = 84/236 (35%), Gaps = 34/236 (14%)
Query: 142 MEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVL----------LKKLRQSQL 191
ME+++K E K K +EER L + L+LEE L L LKK+ +
Sbjct: 40 MEQKMKEEQ-ERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEE 98
Query: 192 QKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSA 251
++ Q +A+ Q H G LS + PG P L +
Sbjct: 99 KRRRKEQSDLTTLTSAAYQQSLTVHTGTHLLS-MQGSPGGHN-RPGTLMAADRAKQMFGP 156
Query: 252 TNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVPCQRT 311
T H + S A P Q Q P G T P +Y P + P Q+
Sbjct: 157 QVLTTRHYVGSAAAFAGTPEHGQFQGSP--GGAYGTA----QPPPHYGPTQPAYSPSQQL 210
Query: 312 TSSAIYMNLASHIQPGTVNRVSSPLPSPSAM------TDAANSQAAAKLALRKQLE 361
+ + + V +S P P P A+ T Q L+L+KQ+E
Sbjct: 211 RAPSAF---------PAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGGALSLQKQME 257
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 38.1 bits (87), Expect = 0.023
Identities = 66/284 (23%), Positives = 113/284 (39%), Gaps = 55/284 (19%)
Query: 141 RMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQKENVVQKT 200
R EER +A + + +K K +EE++Q ++L+ +L+ E LV L Q Q Q++ V+K
Sbjct: 433 REEERRRAEHEQEYKRKQLEEQRQ-AERLQRQLKQERDYLVSL----QHQRQEQRPVEKK 487
Query: 201 PVVQNAASIVQPSPAHVGQQGLSKL-------PSRPGAQGVEPQNLRTLQGHSVIRSATN 253
P+ + PS + + L P+ +Q V Q + L G + A N
Sbjct: 488 PLYHYKEG-MSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSG---FQEALN 543
Query: 254 TTLPHMLMSQRVIAPN------PAQL----------QGQRGPPK---------PGLVRTT 288
T + M ++ P P ++ Q + PPK P L R
Sbjct: 544 VTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKN 603
Query: 289 TPN----MNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTD 344
+P + P + QP +S+ +RT I + G+ + S+P PS+
Sbjct: 604 SPGNGSALGPRLGSQPIRASNPDLRRT--EPILESPLQRTSSGSSSSSSTPSSQPSSQGG 661
Query: 345 A-ANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSE 387
+ SQA + E+T + +P+L P+ E
Sbjct: 662 SQPGSQAGSS-------ERTRVRANSKSEGSPVLPHEPAKVKPE 698
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 38.1 bits (87), Expect = 0.023
Identities = 66/284 (23%), Positives = 113/284 (39%), Gaps = 55/284 (19%)
Query: 141 RMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQKENVVQKT 200
R EER +A + + +K K +EE++Q ++L+ +L+ E LV L Q Q Q++ V+K
Sbjct: 433 REEERRRAEHEQEYKRKQLEEQRQ-AERLQRQLKQERDYLVSL----QHQRQEQRPVEKK 487
Query: 201 PVVQNAASIVQPSPAHVGQQGLSKL-------PSRPGAQGVEPQNLRTLQGHSVIRSATN 253
P+ + PS + + L P+ +Q V Q + L G + A N
Sbjct: 488 PLYHYKEG-MSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSG---FQEALN 543
Query: 254 TTLPHMLMSQRVIAPN------PAQL----------QGQRGPPK---------PGLVRTT 288
T + M ++ P P ++ Q + PPK P L R
Sbjct: 544 VTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKN 603
Query: 289 TPN----MNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTD 344
+P + P + QP +S+ +RT I + G+ + S+P PS+
Sbjct: 604 SPGNGSALGPRLGSQPIRASNPDLRRT--EPILESPLQRTSSGSSSSSSTPSSQPSSQGG 661
Query: 345 A-ANSQAAAKLALRKQLEKTLLEIPPPKPPAPLLHFLPSAANSE 387
+ SQA + E+T + +P+L P+ E
Sbjct: 662 SQPGSQAGSS-------ERTRVRANSKSEGSPVLPHEPAKVKPE 698
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 38.1 bits (87), Expect = 0.023
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 4/128 (3%)
Query: 190 QLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSR---PGAQGVEPQNLRTLQGHS 246
Q ++ ++Q+ + Q S QP+P Q LS P PG Q + +
Sbjct: 2251 QALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAP 2310
Query: 247 VIRSATNTTLPHMLMSQRVIA-PNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSS 305
V + PH S R+ P+P + Q G P PGL T +++ P+ S+
Sbjct: 2311 VQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAM 2370
Query: 306 VPCQRTTS 313
+P T S
Sbjct: 2371 LPQLNTPS 2378
Score = 34.7 bits (78), Expect = 0.25
Identities = 74/329 (22%), Positives = 117/329 (35%), Gaps = 46/329 (13%)
Query: 229 PGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTT 288
PG+Q + P +L + + V + +P M Q AP P Q P PGL R
Sbjct: 1953 PGSQ-MAPVSLNVPRPNQV----SGPVMPSMPPGQWQQAPLPQQ------QPMPGLPRPV 2001
Query: 289 TPNMNPAINYQPQSSSSVPCQRTTSSAIY---MNLASHIQPGTVNRVSSPLPSPSAMTDA 345
A P+ S P + + SA+ L S P +V + L S + A
Sbjct: 2002 ISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA 2061
Query: 346 ANSQAAAKLALRK--QLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVID 403
Q AK + + L+ P P P +H PS N + V + +
Sbjct: 2062 FIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQA----GVPRPGVP 2117
Query: 404 SQGKSCASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCMTSNQKKA-LKAEHTNRLK 462
Q ++ L G+ L N A + ++ L+
Sbjct: 2118 PQQQAMGGL---------------------NPQGQALNIMNPGHNPNMASMNPQYREMLR 2156
Query: 463 NAFVKALQQEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRGI 522
++ QQ+Q+ +Q+ QQQ S A ++ + + A Q Q +Q+ +
Sbjct: 2157 RQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHL 2216
Query: 523 PTSARSMLSNFAQAPQLSVPGGLLGMPGV 551
P SM AQ QL G +G PG+
Sbjct: 2217 PLQGSSMGQMAAQMGQL----GQMGQPGL 2241
Score = 30.0 bits (66), Expect = 6.3
Identities = 45/187 (24%), Positives = 68/187 (36%), Gaps = 38/187 (20%)
Query: 188 QSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSV 247
QSQ +N + P A S+ P Q G+S+ PGA P N+ Q
Sbjct: 752 QSQFLPQN---QFPSSSGAMSVGMGQPP--AQTGVSQ-GQVPGAALPNPLNMLGPQA--- 802
Query: 248 IRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVP 307
+ LP ++Q + P P G P L TT P M P QP + + P
Sbjct: 803 ------SQLPCPPVTQSPLHPTPPPASTAAG--MPSLQHTTPPGMTPP---QPAAPTQ-P 850
Query: 308 CQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEI 367
+SS +P P+P ++ A +Q+ + Q + T
Sbjct: 851 STPVSSSG-----------------QTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQ 893
Query: 368 PPPKPPA 374
P +PP+
Sbjct: 894 TPVQPPS 900
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 38.1 bits (87), Expect = 0.023
Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 4/128 (3%)
Query: 190 QLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSR---PGAQGVEPQNLRTLQGHS 246
Q ++ ++Q+ + Q S QP+P Q LS P PG Q + +
Sbjct: 2289 QALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAP 2348
Query: 247 VIRSATNTTLPHMLMSQRVIA-PNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSS 305
V + PH S R+ P+P + Q G P PGL T +++ P+ S+
Sbjct: 2349 VQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAM 2408
Query: 306 VPCQRTTS 313
+P T S
Sbjct: 2409 LPQLNTPS 2416
Score = 34.7 bits (78), Expect = 0.25
Identities = 74/329 (22%), Positives = 117/329 (35%), Gaps = 46/329 (13%)
Query: 229 PGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTT 288
PG+Q + P +L + + V + +P M Q AP P Q P PGL R
Sbjct: 1991 PGSQ-MAPVSLNVPRPNQV----SGPVMPSMPPGQWQQAPLPQQ------QPMPGLPRPV 2039
Query: 289 TPNMNPAINYQPQSSSSVPCQRTTSSAIY---MNLASHIQPGTVNRVSSPLPSPSAMTDA 345
A P+ S P + + SA+ L S P +V + L S + A
Sbjct: 2040 ISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA 2099
Query: 346 ANSQAAAKLALRK--QLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVID 403
Q AK + + L+ P P P +H PS N + V + +
Sbjct: 2100 FIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQA----GVPRPGVP 2155
Query: 404 SQGKSCASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCMTSNQKKA-LKAEHTNRLK 462
Q ++ L G+ L N A + ++ L+
Sbjct: 2156 PQQQAMGGL---------------------NPQGQALNIMNPGHNPNMASMNPQYREMLR 2194
Query: 463 NAFVKALQQEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRGI 522
++ QQ+Q+ +Q+ QQQ S A ++ + + A Q Q +Q+ +
Sbjct: 2195 RQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHL 2254
Query: 523 PTSARSMLSNFAQAPQLSVPGGLLGMPGV 551
P SM AQ QL G +G PG+
Sbjct: 2255 PLQGSSMGQMAAQMGQL----GQMGQPGL 2279
Score = 30.0 bits (66), Expect = 6.3
Identities = 45/187 (24%), Positives = 68/187 (36%), Gaps = 38/187 (20%)
Query: 188 QSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSV 247
QSQ +N + P A S+ P Q G+S+ PGA P N+ Q
Sbjct: 790 QSQFLPQN---QFPSSSGAMSVGMGQPP--AQTGVSQ-GQVPGAALPNPLNMLGPQA--- 840
Query: 248 IRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVP 307
+ LP ++Q + P P G P L TT P M P QP + + P
Sbjct: 841 ------SQLPCPPVTQSPLHPTPPPASTAAG--MPSLQHTTPPGMTPP---QPAAPTQ-P 888
Query: 308 CQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEI 367
+SS +P P+P ++ A +Q+ + Q + T
Sbjct: 889 STPVSSSG-----------------QTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQ 931
Query: 368 PPPKPPA 374
P +PP+
Sbjct: 932 TPVQPPS 938
>gi|51093863 hypothetical protein LOC64855 isoform 1 [Homo sapiens]
Length = 746
Score = 37.4 bits (85), Expect = 0.039
Identities = 41/198 (20%), Positives = 82/198 (41%), Gaps = 12/198 (6%)
Query: 165 LIKQLRDELRLEEARLVLLKKLRQSQLQ-KENVVQKTPVVQNAAS----IVQPSPAHVGQ 219
L++ +E+ L+ +L+ ++++ +Q K N+ + + V+ N+ + + +P G+
Sbjct: 532 LVENTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGE 591
Query: 220 Q------GLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQL 273
+ G S PS P + + + R Q SV++ LP + +P +
Sbjct: 592 EYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDE-EVGLPFEASPESPPPASPDGV 650
Query: 274 QGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVS 333
RG GL + P P +N P S P +S+ + H+ PG +
Sbjct: 651 TEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLG 710
Query: 334 SPLPSPSAMTDAANSQAA 351
P PS + +S ++
Sbjct: 711 PPKPSDQETGEQVSSPSS 728
>gi|79750824 hypothetical protein LOC64855 isoform 2 [Homo sapiens]
Length = 733
Score = 37.4 bits (85), Expect = 0.039
Identities = 41/198 (20%), Positives = 82/198 (41%), Gaps = 12/198 (6%)
Query: 165 LIKQLRDELRLEEARLVLLKKLRQSQLQ-KENVVQKTPVVQNAAS----IVQPSPAHVGQ 219
L++ +E+ L+ +L+ ++++ +Q K N+ + + V+ N+ + + +P G+
Sbjct: 519 LVENTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGE 578
Query: 220 Q------GLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQL 273
+ G S PS P + + + R Q SV++ LP + +P +
Sbjct: 579 EYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDE-EVGLPFEASPESPPPASPDGV 637
Query: 274 QGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVS 333
RG GL + P P +N P S P +S+ + H+ PG +
Sbjct: 638 TEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLG 697
Query: 334 SPLPSPSAMTDAANSQAA 351
P PS + +S ++
Sbjct: 698 PPKPSDQETGEQVSSPSS 715
>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
sapiens]
Length = 1309
Score = 37.4 bits (85), Expect = 0.039
Identities = 42/195 (21%), Positives = 81/195 (41%), Gaps = 19/195 (9%)
Query: 199 KTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTT--- 255
+T ++N + V P+ +V + +++ R + + + + S S +T+
Sbjct: 1033 RTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKISKQTSVLHTSRSF 1092
Query: 256 ---LPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVP-CQRT 311
L H L S + +P P P TTP +PA + +++S P +
Sbjct: 1093 SSGLHHSLSSSESLPGSPTHSLS----PSP-----TTPCRSPAPDVPADTTASPPSASPS 1143
Query: 312 TSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPK 371
+SS A H +P +++ +++ L P T S ++ + L + PPP+
Sbjct: 1144 SSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPS---PLACPPISAPPPR 1200
Query: 372 PPAPLLHFLPSAANS 386
P+PL P+ A S
Sbjct: 1201 SPSPLPGHPPAPARS 1215
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 36.6 bits (83), Expect = 0.067
Identities = 39/170 (22%), Positives = 70/170 (41%), Gaps = 23/170 (13%)
Query: 40 MERLKMLALLKRKDLANLEVPHELPTKQDGSGVKGYEEKLNGNLRPHGDNRTAGRPGKEN 99
+E+LK K+K +A E T Q+ KG E+ N L + +E
Sbjct: 545 LEKLKRKEKRKKKSVAGKE--DNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEE 602
Query: 100 INDEPVDMSARRSEPERGRLTPSPDIIVLSDNEASSPRSSSRMEERLKAANLEM---FKG 156
+E D DI ++ S S + + AN+ K
Sbjct: 603 EEEEEED-----------------DIDGGESSDESDSESDEKANYQADLANITCEIAIKQ 645
Query: 157 KGIEERQQLIKQLRDELRLEEARLVLLK-KLRQSQLQKENVVQKTPVVQN 205
K I+E + K+L+ + E +L++L+ K+R +QL+++ V+Q V++
Sbjct: 646 KLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVES 695
>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
Length = 931
Score = 36.2 bits (82), Expect = 0.087
Identities = 56/239 (23%), Positives = 86/239 (35%), Gaps = 53/239 (22%)
Query: 296 INYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVN-----RVSSPLPSPSAMTDAANSQA 350
+NY + SS + ++ + ASH G+V RVS PL S T A+ +Q
Sbjct: 104 VNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSA---TSASPTQV 160
Query: 351 AAKLAL-RKQLEKTLLEIPPPKPPAPLLHFLPSAANSEFIYMVGLEEVVQSVIDSQGKSC 409
++L + R E L PP PP PLL PS N I KS
Sbjct: 161 VSQLPMGRDSREMLFLAEQPPLPPPPLLP--PSLTNGTTI--------------PTAKST 204
Query: 410 ASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCMTSNQKKALKAEHTNRLKNAFVKAL 469
+L++ + K E+ S + K LK + VK L
Sbjct: 205 PTLIK-------------------QSQPKSASEKSQRSKKAKELKPK---------VKKL 236
Query: 470 QQEQEIEQRLQQQAALSPTTAPAVSSVSKQETIMRHHTLRQAPQPQSSLQRGIPTSARS 528
+ Q I +Q P + + +Q+ ++ L Q Q + Q +P +S
Sbjct: 237 KYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQQHHNYQAILPAPPKS 295
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 36.2 bits (82), Expect = 0.087
Identities = 44/189 (23%), Positives = 76/189 (40%), Gaps = 25/189 (13%)
Query: 141 RMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQKENVVQKT 200
R EER +A + + +K K +EE++Q ++L+ +L+ E LV L+ RQ Q
Sbjct: 433 REEERRRAEHEQEYKRKQLEEQRQ-AERLQRQLKQERDYLVSLQHQRQEQRP-------- 483
Query: 201 PVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQG-----HSVIRSATNTT 255
V+ P + ++G+S A+ VE ++ Q H V ++
Sbjct: 484 ---------VEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPN 534
Query: 256 LPHMLMSQRVIAPNPAQLQGQRGPPKPGLVR-TTTPNMNPAINYQPQSSSSVPCQRTTSS 314
LP S + PA+ P P + + PA+ QS P + +
Sbjct: 535 LPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALT-ASQSVHEQPTKGLSGF 593
Query: 315 AIYMNLASH 323
+N+ SH
Sbjct: 594 QEALNVTSH 602
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 36.2 bits (82), Expect = 0.087
Identities = 44/189 (23%), Positives = 76/189 (40%), Gaps = 25/189 (13%)
Query: 141 RMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQKENVVQKT 200
R EER +A + + +K K +EE++Q ++L+ +L+ E LV L+ RQ Q
Sbjct: 433 REEERRRAEHEQEYKRKQLEEQRQ-AERLQRQLKQERDYLVSLQHQRQEQRP-------- 483
Query: 201 PVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQG-----HSVIRSATNTT 255
V+ P + ++G+S A+ VE ++ Q H V ++
Sbjct: 484 ---------VEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPN 534
Query: 256 LPHMLMSQRVIAPNPAQLQGQRGPPKPGLVR-TTTPNMNPAINYQPQSSSSVPCQRTTSS 314
LP S + PA+ P P + + PA+ QS P + +
Sbjct: 535 LPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALT-ASQSVHEQPTKGLSGF 593
Query: 315 AIYMNLASH 323
+N+ SH
Sbjct: 594 QEALNVTSH 602
>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
Length = 525
Score = 36.2 bits (82), Expect = 0.087
Identities = 59/238 (24%), Positives = 98/238 (41%), Gaps = 42/238 (17%)
Query: 97 KENINDEPVDMSARRSEPE-----RGRLTPSPDIIVLSDNEASSPRSSSRMEERLKAANL 151
K N+ D+ V+ ++SEPE ++ + ++ D S P S ++ L ++
Sbjct: 271 KLNVIDDDVE-EIKKSEPEPVYIDEDKMDRALQVLQSIDPTDSKPDS----QDLLDLEDI 325
Query: 152 EMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQKENVVQKTPVVQNAASIVQ 211
G I+E+ + I + EL E + +L+ L +V + PV + S +
Sbjct: 326 CQQMGPMIDEKLEEIDRKHSEL--SELNVKVLEALELYN----KLVNEAPVY-SVYSKLH 378
Query: 212 PSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPA 271
P PAH P + GV P +Q H M Q + A
Sbjct: 379 P-PAHYP----------PASSGV-PMQTYPVQSHG-----------GNYMGQSIHQVTVA 415
Query: 272 QLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVPC-QRTTSSAIYMNLASHIQPGT 328
Q GP + G +R+ PN+N ++ QP +S + Q T S+ YMN S++Q T
Sbjct: 416 QSYSL-GPDQIGPLRSLPPNVNSSVTAQPAQTSYLSTGQDTVSNPTYMNQNSNLQSAT 472
>gi|157266269 GATA like protein-1 [Homo sapiens]
Length = 271
Score = 36.2 bits (82), Expect = 0.087
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 415 VEPFVCAQCRTDFTPHWKQEKNGKILCEQC 444
+EP CA CRT TP W+ ++G LC C
Sbjct: 201 LEPRRCASCRTQRTPLWRDAEDGTPLCNAC 230
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 35.0 bits (79), Expect = 0.19
Identities = 46/197 (23%), Positives = 73/197 (37%), Gaps = 21/197 (10%)
Query: 187 RQSQLQKENVVQKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQG-VEPQNLRTLQGH 245
+ S Q V ++TP +Q+ + QP + G +P QG PQ QG
Sbjct: 717 QMSMAQPPIVPRQTPPLQHHGQLAQPGALNP-PMGYGPRMQQPSNQGQFLPQTQFPSQGM 775
Query: 246 SVIRSATNTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNM-NPAINYQPQSSS 304
+V + +SQ ++ + + PP P + PA++ S S
Sbjct: 776 NVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN--SPS 833
Query: 305 SVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTL 364
VP + T ++ + P T + +P+P+P AM SQA
Sbjct: 834 PVPSRTPTPHHTPPSIGAQQPPATT--IPAPVPTPPAMPPGPQSQA-------------- 877
Query: 365 LEIPPPKPPAPLLHFLP 381
L PP + P P LP
Sbjct: 878 LHPPPRQTPTPPTTQLP 894
Score = 35.0 bits (79), Expect = 0.19
Identities = 43/194 (22%), Positives = 69/194 (35%), Gaps = 30/194 (15%)
Query: 197 VQKTPVVQNAASIVQPSPAHVGQQGLSKLPSR----PGAQGVEPQNLRTLQGHSVIRSAT 252
V P +QN + P A V + GL + + P G+ PQ + H+ + S
Sbjct: 2124 VHSNPAMQN----MNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQF 2179
Query: 253 NTTLPHMLMSQRVIAPNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSSSVPCQRTT 312
L M Q+ Q QG PG+ + Y PQ +
Sbjct: 2180 RDILRRQQMMQQ------QQQQGAGPGIGPGMANHNQFQQPQGVGYPPQQQQRM------ 2227
Query: 313 SSAIYMNLASHIQPGTVNRVSSPLPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPKP 372
+ +Q G + ++ LP A+ QA + L++Q+ + P P
Sbjct: 2228 -----QHHMQQMQQGNMGQIGQ-LPQALGAEAGASLQAYQQRLLQQQMGSPV----QPNP 2277
Query: 373 PAPLLHFLPSAANS 386
+P H LP+ A S
Sbjct: 2278 MSPQQHMLPNQAQS 2291
Score = 32.7 bits (73), Expect = 0.97
Identities = 35/125 (28%), Positives = 57/125 (45%), Gaps = 7/125 (5%)
Query: 219 QQG-LSKLPSRPGAQGVEP-QNLRTLQGHSVIRSATNTTLPHMLMSQRVIAPNPAQ---L 273
QQG + ++ P A G E +L+ Q + + + P+ + Q+ + PN AQ L
Sbjct: 2235 QQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHL 2294
Query: 274 QGQRGPPK-PGLVRTTTPNMNPAINYQPQSSSSVPCQRTTSSAIYMN-LASHIQPGTVNR 331
QGQ+ P VR+ P +P QP SS P + S +++ S PG V
Sbjct: 2295 QGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAA 2354
Query: 332 VSSPL 336
++P+
Sbjct: 2355 QANPM 2359
Score = 31.2 bits (69), Expect = 2.8
Identities = 31/111 (27%), Positives = 41/111 (36%), Gaps = 4/111 (3%)
Query: 198 QKTPVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQNLRTLQGHS---VIRSATNT 254
Q+ + Q S VQP+P Q L P QG + N + Q S V +
Sbjct: 2261 QQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQS 2320
Query: 255 TLPHMLMSQRVIA-PNPAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQSSS 304
PH S R+ P+P + Q P PGLV M P +S
Sbjct: 2321 QPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNS 2371
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 35.0 bits (79), Expect = 0.19
Identities = 43/201 (21%), Positives = 88/201 (43%), Gaps = 20/201 (9%)
Query: 141 RMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQKENVVQKT 200
R EER +A + + + + +EE Q+ ++ L+ +L L E L+L K +Q + Q++ +
Sbjct: 433 REEERRRAEHEQEYIRRQLEEEQRQLEILQQQL-LHEQALLLEYKRKQLEEQRQAERLQR 491
Query: 201 PVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQN----LRTLQGHSVIRSATNTTL 256
+ Q +V Q+ + K P +G+ P + ++ S + ++ +
Sbjct: 492 QLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAM 551
Query: 257 PHMLMSQRVIAPN------PAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQ-----SSSS 305
PH ++ R+ PN + G + P ++R P + + + Q +S S
Sbjct: 552 PHK-VANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQS 610
Query: 306 VPCQRTTSSAIY---MNLASH 323
V Q T + + +N+ SH
Sbjct: 611 VHEQPTKGLSGFQEALNVTSH 631
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 35.0 bits (79), Expect = 0.19
Identities = 43/201 (21%), Positives = 88/201 (43%), Gaps = 20/201 (9%)
Query: 141 RMEERLKAANLEMFKGKGIEERQQLIKQLRDELRLEEARLVLLKKLRQSQLQKENVVQKT 200
R EER +A + + + + +EE Q+ ++ L+ +L L E L+L K +Q + Q++ +
Sbjct: 433 REEERRRAEHEQEYIRRQLEEEQRQLEILQQQL-LHEQALLLEYKRKQLEEQRQAERLQR 491
Query: 201 PVVQNAASIVQPSPAHVGQQGLSKLPSRPGAQGVEPQN----LRTLQGHSVIRSATNTTL 256
+ Q +V Q+ + K P +G+ P + ++ S + ++ +
Sbjct: 492 QLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAM 551
Query: 257 PHMLMSQRVIAPN------PAQLQGQRGPPKPGLVRTTTPNMNPAINYQPQ-----SSSS 305
PH ++ R+ PN + G + P ++R P + + + Q +S S
Sbjct: 552 PHK-VANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQS 610
Query: 306 VPCQRTTSSAIY---MNLASH 323
V Q T + + +N+ SH
Sbjct: 611 VHEQPTKGLSGFQEALNVTSH 631
>gi|148612879 polyhomeotic like 3 [Homo sapiens]
Length = 995
Score = 35.0 bits (79), Expect = 0.19
Identities = 59/284 (20%), Positives = 112/284 (39%), Gaps = 36/284 (12%)
Query: 107 MSARRSEPERGRLTPSPDIIVLSDNEASSPRSSSRMEERLKAANLEMFKGKGIEERQQLI 166
+S R PE + SP + ++ +++ +S + + + A+ + + + QQ I
Sbjct: 269 ISQRDPSPESNKKGESPSL----ESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQ-I 323
Query: 167 KQLRDELRLEEARLVLLKKLRQSQ-LQKENVVQKTPVVQNAASI----VQPSPAHVGQQG 221
++ +L+L ++ +Q Q + +N Q P Q+ + + P+P++ Q
Sbjct: 324 PLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQH 383
Query: 222 LSKLPSRPGAQGVEPQNLRTLQGHSVIRSATNTTLPH-----MLMSQRVIAPNPAQLQGQ 276
S + S P V P ++ Q SV+ S P ++ Q +I P+P L
Sbjct: 384 CSPIQSHPSPLTVSPNQSQSAQ-QSVVVSPPPPHSPSQSPTIIIHPQALIQPHP--LVSS 440
Query: 277 RGPPKPGLVRTTTPNMNPAINYQPQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSP- 335
P P L ++T + S +P HI P + + SP
Sbjct: 441 ALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVV----------HIGPVQQSALVSPG 490
Query: 336 --LPSPSAMTDAANSQAAAKLALRKQLEKTLLEIPPPK-PPAPL 376
+ SPS ++ + +A Q+ + PP + PP PL
Sbjct: 491 QQIVSPSHQQYSSLQSSPIPIASPPQMSTS----PPAQIPPLPL 530
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 394 LEEVVQSVIDSQGKSCASLLRVEPFVCAQCRTDFTPHWKQEKNGKILCEQCMTSNQKKAL 453
+++++ S D+ +L++ + C T + HWK E KIL + +K L
Sbjct: 1122 IQKLITSNTDASDGDSVALVKETVVISPPC-TGSSEHWKPELEEKILALEKEKEQLQKKL 1180
Query: 454 KAEHTNRLKNAFVKALQQEQEIEQRLQQQ 482
+ T+R K KA ++E+ + + L+QQ
Sbjct: 1181 QEALTSR-KAILKKAQEKERHLREELKQQ 1208
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,436,048
Number of Sequences: 37866
Number of extensions: 1272473
Number of successful extensions: 6963
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 237
Number of HSP's that attempted gapping in prelim test: 6538
Number of HSP's gapped (non-prelim): 704
length of query: 593
length of database: 18,247,518
effective HSP length: 108
effective length of query: 485
effective length of database: 14,157,990
effective search space: 6866625150
effective search space used: 6866625150
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.