Search of human proteins with 20336272

Search of human proteins with 20336272

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20336272 solute carrier family 26, member 1 isoform a [Homo
sapiens]
         (701 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47131207 solute carrier family 26, member 1 isoform a [Homo s...  1375   0.0  
gi|20336272 solute carrier family 26, member 1 isoform a [Homo s...  1375   0.0  
gi|100913030 solute carrier family 26 member 2 [Homo sapiens]         642   0.0  
gi|39752683 prestin isoform a [Homo sapiens]                          414   e-115
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s...   411   e-114
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s...   406   e-113
gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s...   405   e-113
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s...   405   e-113
gi|4505697 pendrin [Homo sapiens]                                     404   e-112
gi|45827800 prestin isoform b [Homo sapiens]                          400   e-111
gi|20336274 solute carrier family 26, member 1 isoform b [Homo s...   388   e-107
gi|4557535 solute carrier family 26, member 3 [Homo sapiens]          347   2e-95
gi|45827802 prestin isoform c [Homo sapiens]                          335   6e-92
gi|16418413 solute carrier family 26, member 9 isoform a [Homo s...   302   8e-82
gi|217272867 solute carrier family 26, member 9 isoform b [Homo ...   302   8e-82
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s...   262   7e-70
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s...   262   7e-70
gi|65506789 solute carrier family 26, member 10 [Homo sapiens]        239   8e-63
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s...   234   3e-61
gi|45827804 prestin isoform d [Homo sapiens]                          201   2e-51
gi|85540447 solute carrier family 26, member 11 [Homo sapiens]        176   5e-44
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s...   138   2e-32
gi|217272870 solute carrier family 26, member 9 isoform c [Homo ...   127   4e-29
gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [H...    34   0.40 
gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [H...    34   0.53 
gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo s...    31   3.4  
gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo s...    31   3.4  
gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo s...    31   3.4  
gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo sa...    31   3.4  
gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo s...    31   3.4  

>gi|47131207 solute carrier family 26, member 1 isoform a [Homo
           sapiens]
          Length = 701

 Score = 1375 bits (3560), Expect = 0.0
 Identities = 701/701 (100%), Positives = 701/701 (100%)

Query: 1   MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL 60
           MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL
Sbjct: 1   MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL 60

Query: 61  RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH 120
           RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH
Sbjct: 61  RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH 120

Query: 121 VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV 180
           VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV
Sbjct: 121 VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV 180

Query: 181 ATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQ 240
           ATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQ
Sbjct: 181 ATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQ 240

Query: 241 GPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIV 300
           GPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIV
Sbjct: 241 GPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIV 300

Query: 301 VATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLA 360
           VATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLA
Sbjct: 301 VATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLA 360

Query: 361 EMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSA 420
           EMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSA
Sbjct: 361 EMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSA 420

Query: 421 TVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAAT 480
           TVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAAT
Sbjct: 421 TVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAAT 480

Query: 481 CMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVF 540
           CMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVF
Sbjct: 481 CMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVF 540

Query: 541 RFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRA 600
           RFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRA
Sbjct: 541 RFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRA 600

Query: 601 ALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRG 660
           ALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRG
Sbjct: 601 ALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRG 660

Query: 661 GFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL 701
           GFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL
Sbjct: 661 GFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL 701


>gi|20336272 solute carrier family 26, member 1 isoform a [Homo
           sapiens]
          Length = 701

 Score = 1375 bits (3560), Expect = 0.0
 Identities = 701/701 (100%), Positives = 701/701 (100%)

Query: 1   MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL 60
           MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL
Sbjct: 1   MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL 60

Query: 61  RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH 120
           RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH
Sbjct: 61  RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH 120

Query: 121 VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV 180
           VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV
Sbjct: 121 VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV 180

Query: 181 ATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQ 240
           ATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQ
Sbjct: 181 ATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQ 240

Query: 241 GPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIV 300
           GPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIV
Sbjct: 241 GPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIV 300

Query: 301 VATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLA 360
           VATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLA
Sbjct: 301 VATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLA 360

Query: 361 EMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSA 420
           EMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSA
Sbjct: 361 EMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSA 420

Query: 421 TVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAAT 480
           TVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAAT
Sbjct: 421 TVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAAT 480

Query: 481 CMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVF 540
           CMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVF
Sbjct: 481 CMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVF 540

Query: 541 RFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRA 600
           RFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRA
Sbjct: 541 RFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRA 600

Query: 601 ALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRG 660
           ALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRG
Sbjct: 601 ALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRG 660

Query: 661 GFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL 701
           GFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL
Sbjct: 661 GFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL 701


>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
          Length = 739

 Score =  642 bits (1655), Expect = 0.0
 Identities = 321/673 (47%), Positives = 462/673 (68%), Gaps = 11/673 (1%)

Query: 17  VRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSG 76
           + RQ  +    +E +  +L  +C CS    + ++   LP  +WL +Y  ++ + GDVMSG
Sbjct: 56  IERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSG 115

Query: 77  LVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQV 136
           L++GI+LVPQ+IAYSLLAG +P+Y LYTSFFA++IYFL+GTSRH+SVGIF +LCLM+G+ 
Sbjct: 116 LIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGET 175

Query: 137 VDRELQLAGFDPSQDGLQPG--ANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVL 194
           VDRELQ AG+D +      G  +N STL    +   C + CYAI V + +T + G+YQV 
Sbjct: 176 VDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVA 235

Query: 195 MGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLR 254
           MG  ++GFVS YLS  LL GF  GAS TILTSQ K+LLG+ +PR  G G ++ TW+ + R
Sbjct: 236 MGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFR 295

Query: 255 GAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKR 314
              + N+CD++TS +CL VLL  KEL++ ++ +L+ P+P EL+V+V ATL SHFG+LH+ 
Sbjct: 296 NIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHEN 355

Query: 315 FGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRAN 374
           + SS+AG IPTGFMPP+VPE  L+  VA+DA+A++++  A ++SL+EMFA+ HGY+V+AN
Sbjct: 356 YNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKAN 415

Query: 375 QELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLF 434
           QE+ A+G CN++P+F HCF TSAALAK+LVK +TGC TQLS VV+A V+LLVLL +APLF
Sbjct: 416 QEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLF 475

Query: 435 HDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGV 494
           + LQ+SVL  + +V+LRGALRK  DLP++W +S  D ++W  T  +  L+STE GLL GV
Sbjct: 476 YSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGV 535

Query: 495 ILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFF 554
             S+  +  RTQ+P+++LL  + ++  +E  + ++ L  +PG+++FRF  PLYY NK+ F
Sbjct: 536 CFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECF 595

Query: 555 LQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAGFHTVVI 614
             +LY  T        A +K   ++  + E     G     +S + +  P     HT+VI
Sbjct: 596 KSALYKQTVNPILIKVAWKK--AAKRKIKEKVVTLGGIQDEMSVQLSHDPLE--LHTIVI 651

Query: 615 DCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEE 674
           DC+ + FLD AG+ TL+++RRDY A+GI +LLA C+P VRD L+ G +  +      EE 
Sbjct: 652 DCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKK-----EEEN 706

Query: 675 QLFLSVHDAVQTA 687
            LF SV++A+  A
Sbjct: 707 LLFYSVYEAMAFA 719


>gi|39752683 prestin isoform a [Homo sapiens]
          Length = 744

 Score =  414 bits (1064), Expect = e-115
 Identities = 233/683 (34%), Positives = 389/683 (56%), Gaps = 49/683 (7%)

Query: 40  SCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPI 99
           +C+   +R ++   LP T+WL  Y+ +EY+ GD++SG+  G++ +PQ +A+++LA + PI
Sbjct: 51  TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPI 110

Query: 100 YSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANS 159
           + LY+SF+  ++Y  +GTSRH+S+G F+++ LM+G V  R +         D + PG  +
Sbjct: 111 FGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVP-------DDIVIPGGVN 163

Query: 160 STLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGA 219
           +T NG+ A     RD   ++VA ++TL++G+ Q  +GV R GFV+ YL++PL+ GF   A
Sbjct: 164 AT-NGTEA-----RDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217

Query: 220 SVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKE 279
           +V + TS LK+L GV+  R+ G   VV + +++L+     NVC +    +   +LL  KE
Sbjct: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277

Query: 280 LSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQ 339
            ++R++ +L  P+P E   +V+ T +S    L + +   V G +P G +PP  P+  L  
Sbjct: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337

Query: 340 RVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAAL 399
            V +DA+A+A+V  + +IS+A+  A  HGY V  NQEL+A+G CN + +    F+ S +L
Sbjct: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397

Query: 400 AKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWD 459
           ++SLV+  TG +TQL+  +++ ++LLV+LA   LF  L ++VL+ +++V+L+G   +  D
Sbjct: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457

Query: 460 LPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDT 519
           LP  WR S  +  +W  T  + + +  + GL+  VI++LL++  RTQ P   +L ++ +T
Sbjct: 458 LPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPET 517

Query: 520 AFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD-AGCMAARRK---- 574
             Y D   +E +   PG+++F+   P+YYAN D +  +L   TG++ A  M ARRK    
Sbjct: 518 DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRK 577

Query: 575 --------EGGSETGVGEGGPAQGEDLG------------PVSTRAAL-------VPAAA 607
                      + T V       GED              P+  ++         +P   
Sbjct: 578 YAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGD 637

Query: 608 GFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGP 667
             HTV++D   + F+D+ GV TL  + ++YG +GI + LA CS  V + L+R  F  E P
Sbjct: 638 NVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFF-ENP 696

Query: 668 GDTAEEEQLFLSVHDAVQTARAR 690
              A  E LF S+HDAV  ++ R
Sbjct: 697 ---ALWELLFHSIHDAVLGSQLR 716


>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
           sapiens]
          Length = 740

 Score =  411 bits (1056), Expect = e-114
 Identities = 236/692 (34%), Positives = 379/692 (54%), Gaps = 63/692 (9%)

Query: 34  RLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLL 93
           R W  CS +     AL+   LP   WL +Y  R++L GD++SGL + I+ +PQ +AY+LL
Sbjct: 57  RTWLQCSRAR--AYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALL 114

Query: 94  AGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGL 153
           AGL P++ LY+SF+   IYFL GTSRH+SVG F+++ +MVG V +              L
Sbjct: 115 AGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE-------------SL 161

Query: 154 QPGA-NSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLL 212
            P A N S +N +A      RD   ++VA+ L+++ GL+QV +G++  GFV  YLS+PL+
Sbjct: 162 APQALNDSMINETA------RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLV 215

Query: 213 DGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLA 272
            G+   A+V +  SQLK++ G+ +  H GP  ++ T L +     Q+ V  VVT+ V   
Sbjct: 216 RGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGV 275

Query: 273 VLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQV 332
           VL+  K L+D+ + +L +P+P ELL ++ AT +S+   L  RF   V G+IP G +PP  
Sbjct: 276 VLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVA 335

Query: 333 PEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHC 392
           P  +L  ++   A  +A+V  A +ISL ++FA  HGY V +NQEL+A+G  N++     C
Sbjct: 336 PNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQC 395

Query: 393 FATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRG 452
           F  S ++++SLV+ +TG  +Q++  +S+  +LL+++ L  LFHDL ++VLA +I+V+L+G
Sbjct: 396 FPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKG 455

Query: 453 ALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTAL 512
            LR++ D+  LW+ + AD L+W  T    +L++ + GL+  VI SLL +  RTQ P  ++
Sbjct: 456 MLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515

Query: 513 LARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD------- 565
           L ++ DT  Y D  E+       GV+VFR    +Y+AN +F+  +L    G+D       
Sbjct: 516 LGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQ 575

Query: 566 ------------------------------AGCMAARRKEGGSETGVGEGGPAQGEDLGP 595
                                         + C+A ++   G +         +      
Sbjct: 576 KKKLLKKQEQLKLKQLQKEEKLRKQAGPLLSACLAPQQVSSGDKMEDATANGQEDSKAPD 635

Query: 596 VSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRD 655
            ST  AL      FH++++D   L F+D   + +L+++  D+  + + + +A C  PV  
Sbjct: 636 GSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVS 695

Query: 656 ILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTA 687
            L  G F       +  ++ LF SVHDAV  A
Sbjct: 696 QLEAGHFFDA----SITKKHLFASVHDAVTFA 723


>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
           sapiens]
          Length = 758

 Score =  406 bits (1043), Expect = e-113
 Identities = 240/710 (33%), Positives = 383/710 (53%), Gaps = 81/710 (11%)

Query: 34  RLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLL 93
           R W  CS +     AL+   LP   WL +Y  R++L GD++SGL + I+ +PQ +AY+LL
Sbjct: 57  RTWLQCSRAR--AYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALL 114

Query: 94  AGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGL 153
           AGL P++ LY+SF+   IYFL GTSRH+SVG F+++ +MVG V +              L
Sbjct: 115 AGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE-------------SL 161

Query: 154 QPGA-NSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLL 212
            P A N S +N +A      RD   ++VA+ L+++ GL+QV +G++  GFV  YLS+PL+
Sbjct: 162 APQALNDSMINETA------RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLV 215

Query: 213 DGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLA 272
            G+   A+V +  SQLK++ G+ +  H GP  ++ T L +     Q+ V  VVT+ V   
Sbjct: 216 RGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGV 275

Query: 273 VLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQV 332
           VL+  K L+D+ + +L +P+P ELL ++ AT +S+   L  RF   V G+IP G +PP  
Sbjct: 276 VLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVA 335

Query: 333 PEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHC 392
           P  +L  ++   A  +A+V  A +ISL ++FA  HGY V +NQEL+A+G  N++     C
Sbjct: 336 PNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQC 395

Query: 393 FATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRG 452
           F  S ++++SLV+ +TG  +Q++  +S+  +LL+++ L  LFHDL ++VLA +I+V+L+G
Sbjct: 396 FPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKG 455

Query: 453 ALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTAL 512
            LR++ D+  LW+ + AD L+W  T    +L++ + GL+  VI SLL +  RTQ P  ++
Sbjct: 456 MLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515

Query: 513 LARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAAR 572
           L ++ DT  Y D  E+       GV+VFR    +Y+AN +F+  +L    G+D   + ++
Sbjct: 516 LGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQ 575

Query: 573 ----------------------RKEGGSETGVG--------------------------- 583
                                 RK+  S  G                             
Sbjct: 576 KKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMVSSG 635

Query: 584 ---EGGPAQGEDLGPV---STRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDY 637
              E   A G++       ST  AL      FH++++D   L F+D   + +L+++  D+
Sbjct: 636 DKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDF 695

Query: 638 GALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTA 687
             + + + +A C  PV   L  G F       +  ++ LF SVHDAV  A
Sbjct: 696 REIEVEVYMAACHSPVVSQLEAGHFFDA----SITKKHLFASVHDAVTFA 741


>gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo
           sapiens]
          Length = 738

 Score =  405 bits (1042), Expect = e-113
 Identities = 240/711 (33%), Positives = 383/711 (53%), Gaps = 82/711 (11%)

Query: 34  RLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLL 93
           R W  CS +     AL+   LP   WL +Y  R++L GD++SGL + I+ +PQ +AY+LL
Sbjct: 36  RTWLQCSRAR--AYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALL 93

Query: 94  AGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGL 153
           AGL P++ LY+SF+   IYFL GTSRH+SVG F+++ +MVG V +              L
Sbjct: 94  AGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE-------------SL 140

Query: 154 QPGA-NSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLL 212
            P A N S +N +A      RD   ++VA+ L+++ GL+QV +G++  GFV  YLS+PL+
Sbjct: 141 APQALNDSMINETA------RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLV 194

Query: 213 DGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLA 272
            G+   A+V +  SQLK++ G+ +  H GP  ++ T L +     Q+ V  VVT+ V   
Sbjct: 195 RGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGV 254

Query: 273 VLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQV 332
           VL+  K L+D+ + +L +P+P ELL ++ AT +S+   L  RF   V G+IP G +PP  
Sbjct: 255 VLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVA 314

Query: 333 PEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHC 392
           P  +L  ++   A  +A+V  A +ISL ++FA  HGY V +NQEL+A+G  N++     C
Sbjct: 315 PNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQC 374

Query: 393 FATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRG 452
           F  S ++++SLV+ +TG  +Q++  +S+  +LL+++ L  LFHDL ++VLA +I+V+L+G
Sbjct: 375 FPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKG 434

Query: 453 ALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTAL 512
            LR++ D+  LW+ + AD L+W  T    +L++ + GL+  VI SLL +  RTQ P  ++
Sbjct: 435 MLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 494

Query: 513 LARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAAR 572
           L ++ DT  Y D  E+       GV+VFR    +Y+AN +F+  +L    G+D   + ++
Sbjct: 495 LGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQ 554

Query: 573 ----------------------RKEGGSETGVG--------------------------- 583
                                 RK+  S  G                             
Sbjct: 555 KKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSS 614

Query: 584 ----EGGPAQGEDLGPV---STRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRD 636
               E   A G++       ST  AL      FH++++D   L F+D   + +L+++  D
Sbjct: 615 GDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHD 674

Query: 637 YGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTA 687
           +  + + + +A C  PV   L  G F       +  ++ LF SVHDAV  A
Sbjct: 675 FREIEVEVYMAACHSPVVSQLEAGHFFDA----SITKKHLFASVHDAVTFA 721


>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
           sapiens]
          Length = 759

 Score =  405 bits (1042), Expect = e-113
 Identities = 240/711 (33%), Positives = 383/711 (53%), Gaps = 82/711 (11%)

Query: 34  RLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLL 93
           R W  CS +     AL+   LP   WL +Y  R++L GD++SGL + I+ +PQ +AY+LL
Sbjct: 57  RTWLQCSRAR--AYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALL 114

Query: 94  AGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGL 153
           AGL P++ LY+SF+   IYFL GTSRH+SVG F+++ +MVG V +              L
Sbjct: 115 AGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE-------------SL 161

Query: 154 QPGA-NSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLL 212
            P A N S +N +A      RD   ++VA+ L+++ GL+QV +G++  GFV  YLS+PL+
Sbjct: 162 APQALNDSMINETA------RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLV 215

Query: 213 DGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLA 272
            G+   A+V +  SQLK++ G+ +  H GP  ++ T L +     Q+ V  VVT+ V   
Sbjct: 216 RGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGV 275

Query: 273 VLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQV 332
           VL+  K L+D+ + +L +P+P ELL ++ AT +S+   L  RF   V G+IP G +PP  
Sbjct: 276 VLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVA 335

Query: 333 PEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHC 392
           P  +L  ++   A  +A+V  A +ISL ++FA  HGY V +NQEL+A+G  N++     C
Sbjct: 336 PNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQC 395

Query: 393 FATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRG 452
           F  S ++++SLV+ +TG  +Q++  +S+  +LL+++ L  LFHDL ++VLA +I+V+L+G
Sbjct: 396 FPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKG 455

Query: 453 ALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTAL 512
            LR++ D+  LW+ + AD L+W  T    +L++ + GL+  VI SLL +  RTQ P  ++
Sbjct: 456 MLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515

Query: 513 LARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAAR 572
           L ++ DT  Y D  E+       GV+VFR    +Y+AN +F+  +L    G+D   + ++
Sbjct: 516 LGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQ 575

Query: 573 ----------------------RKEGGSETGVG--------------------------- 583
                                 RK+  S  G                             
Sbjct: 576 KKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSS 635

Query: 584 ----EGGPAQGEDLGPV---STRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRD 636
               E   A G++       ST  AL      FH++++D   L F+D   + +L+++  D
Sbjct: 636 GDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHD 695

Query: 637 YGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTA 687
           +  + + + +A C  PV   L  G F       +  ++ LF SVHDAV  A
Sbjct: 696 FREIEVEVYMAACHSPVVSQLEAGHFFDA----SITKKHLFASVHDAVTFA 742


>gi|4505697 pendrin [Homo sapiens]
          Length = 780

 Score =  404 bits (1037), Expect = e-112
 Identities = 227/700 (32%), Positives = 381/700 (54%), Gaps = 59/700 (8%)

Query: 28  REMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQA 87
           R+ L+  L   CSCS      +++ L+P   WL +YR +E+L  DV+SG+  G++   Q 
Sbjct: 43  RKTLRESLAKCCSCSRKRAFGVLKTLVPILEWLPKYRVKEWLLSDVISGVSTGLVATLQG 102

Query: 88  IAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFD 147
           +AY+LLA +   Y LY++FF  L YF+ GTSRH+SVG F ++ LMVG VV   L +A   
Sbjct: 103 MAYALLAAVPVGYGLYSAFFPILTYFIFGTSRHISVGPFPVVSLMVGSVV---LSMA--- 156

Query: 148 PSQDGLQPGANSSTLNGSAAMLD-CGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAY 206
           P +  L   +N + LN    M+D   RD   + +A+ALTL+ G+ Q++ G L++GF+  Y
Sbjct: 157 PDEHFLVSSSNGTVLN--TTMIDTAARDTARVLIASALTLLVGIIQLIFGGLQIGFIVRY 214

Query: 207 LSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVT 266
           L+ PL+ GF   A+  +L SQLK +L V    + G   ++ T + + +  G  N+ D   
Sbjct: 215 LADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTLVEIFQNIGDTNLADFTA 274

Query: 267 STVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTG 326
             + + V +A KEL+DR+RH++ VP+P E++V ++AT +S+   L K + + +   IP G
Sbjct: 275 GLLTIVVCMAVKELNDRFRHKIPVPIPIEVIVTIIATAISYGANLEKNYNAGIVKSIPRG 334

Query: 327 FMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVL 386
           F+PP++P   L   +   + ++A+VA A ++S+ +++A  + Y++  NQE +A G  N+ 
Sbjct: 335 FLPPELPPVSLFSEMLAASFSIAVVAYAIAVSVGKVYATKYDYTIDGNQEFIAFGISNIF 394

Query: 387 PAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVI 446
             F  CF  + AL+++ V+ +TG +TQ++ ++SA +V++ +LAL  L   LQ+SVLA V+
Sbjct: 395 SGFFSCFVATTALSRTAVQESTGGKTQVAGIISAAIVMIAILALGKLLEPLQKSVLAAVV 454

Query: 447 VVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQ 506
           + +L+G   ++ D+PRLWR +  DA++W  T    +++  + GLLAG+I  LL++  R Q
Sbjct: 455 IANLKGMFMQLCDIPRLWRQNKIDAVIWVFTCIVSIILGLDLGLLAGLIFGLLTVVLRVQ 514

Query: 507 RPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDA 566
            P    L  I  T  Y+    ++ +    GV++ RF  P++Y N D F + + S  G DA
Sbjct: 515 FPSWNGLGSIPSTDIYKSTKNYKNIEEPQGVKILRFSSPIFYGNVDGFKKCIKSTVGFDA 574

Query: 567 GCMAARR-----------KEG---GSETGVGEGGPAQG---------EDLG--------- 594
             +  +R           K G    ++ G+     +           EDL          
Sbjct: 575 IRVYNKRLKALRKIQKLIKSGQLRATKNGIISDAVSTNNAFEPDEDIEDLEELDIPTKEI 634

Query: 595 ----------PVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISL 644
                     PV      VP     H++V+DC  + FLD  GV +L+ + +++  + +++
Sbjct: 635 EIQVDWNSELPVKVNVPKVP----IHSLVLDCGAISFLDVVGVRSLRVIVKEFQRIDVNV 690

Query: 645 LLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAV 684
             A     V + L + GF      D   ++  FL+VHDA+
Sbjct: 691 YFASLQDYVIEKLEQCGFF----DDNIRKDTFFLTVHDAI 726


>gi|45827800 prestin isoform b [Homo sapiens]
          Length = 685

 Score =  400 bits (1028), Expect = e-111
 Identities = 217/643 (33%), Positives = 368/643 (57%), Gaps = 45/643 (6%)

Query: 40  SCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPI 99
           +C+   +R ++   LP T+WL  Y+ +EY+ GD++SG+  G++ +PQ +A+++LA + PI
Sbjct: 51  TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPI 110

Query: 100 YSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANS 159
           + LY+SF+  ++Y  +GTSRH+S+G F+++ LM+G V  R +         D + PG  +
Sbjct: 111 FGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVP-------DDIVIPGGVN 163

Query: 160 STLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGA 219
           +T NG+ A     RD   ++VA ++TL++G+ Q  +GV R GFV+ YL++PL+ GF   A
Sbjct: 164 AT-NGTEA-----RDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217

Query: 220 SVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKE 279
           +V + TS LK+L GV+  R+ G   VV + +++L+     NVC +    +   +LL  KE
Sbjct: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277

Query: 280 LSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQ 339
            ++R++ +L  P+P E   +V+ T +S    L + +   V G +P G +PP  P+  L  
Sbjct: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337

Query: 340 RVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAAL 399
            V +DA+A+A+V  + +IS+A+  A  HGY V  NQEL+A+G CN + +    F+ S +L
Sbjct: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397

Query: 400 AKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWD 459
           ++SLV+  TG +TQL+  +++ ++LLV+LA   LF  L ++VL+ +++V+L+G   +  D
Sbjct: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457

Query: 460 LPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDT 519
           LP  WR S  +  +W  T  + + +  + GL+  VI++LL++  RTQ P   +L ++ +T
Sbjct: 458 LPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPET 517

Query: 520 AFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD-AGCMAARRK---- 574
             Y D   +E +   PG+++F+   P+YYAN D +  +L   TG++ A  M ARRK    
Sbjct: 518 DVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRK 577

Query: 575 --------EGGSETGVGEGGPAQGEDLG------------PVSTRAAL-------VPAAA 607
                      + T V       GED              P+  ++         +P   
Sbjct: 578 YAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGD 637

Query: 608 GFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCS 650
             HTV++D   + F+D+ GV TL  + ++YG +GI + LA CS
Sbjct: 638 NVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCS 680


>gi|20336274 solute carrier family 26, member 1 isoform b [Homo
           sapiens]
          Length = 224

 Score =  388 bits (996), Expect = e-107
 Identities = 193/196 (98%), Positives = 193/196 (98%)

Query: 1   MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL 60
           MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL
Sbjct: 1   MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWL 60

Query: 61  RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH 120
           RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH
Sbjct: 61  RQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRH 120

Query: 121 VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV 180
           VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV
Sbjct: 121 VSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRV 180

Query: 181 ATALTLMTGLYQVLMG 196
           ATALTLMTGLYQ   G
Sbjct: 181 ATALTLMTGLYQTSWG 196


>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
          Length = 764

 Score =  347 bits (891), Expect = 2e-95
 Identities = 191/527 (36%), Positives = 304/527 (57%), Gaps = 10/527 (1%)

Query: 39  CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQP 98
           CSCS    + +V  L P   WL  YR +E+L  D++SG+  GI+ V Q +A++LL  + P
Sbjct: 43  CSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPP 102

Query: 99  IYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGAN 158
           +Y LY SFF  +IY   GTSRH+SVG F +L +MVG  V   +  A  D +   L    N
Sbjct: 103 VYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNN 162

Query: 159 SSTLNGSAAMLDCGRDCYAIRVATA--LTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFA 216
           S+    ++++LD  R    +RVA A  +T+++G+ Q+  G+LR+GFV  YLS+ L+ GF 
Sbjct: 163 SN----NSSLLDDER----VRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFT 214

Query: 217 MGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLA 276
             A+V +L SQLK +  + +P H  P  +     S+     + N+ D+VT+ + L V+  
Sbjct: 215 TAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSI 274

Query: 277 AKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPR 336
            KE++ R++ +L VP+P E ++ V+A  VS+      RF  +V GD+  GF PP  P+  
Sbjct: 275 VKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVE 334

Query: 337 LMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATS 396
             Q    D   +A+VA A + S+A +++  + Y +  NQEL+A+G  N++      FA S
Sbjct: 335 TFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGS 394

Query: 397 AALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRK 456
            AL++S V+ +TG +TQ++ ++ A +VL+V+LA+  L   LQ+SVLA + + +L+G L +
Sbjct: 395 TALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQ 454

Query: 457 VWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARI 516
             ++ RLWR    D L+W  T    +++    GL A V   LL++  RTQ P+ + LA I
Sbjct: 455 FAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANI 514

Query: 517 GDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTG 563
           G T  Y++  ++  +    GV++FR   P+Y+AN  FF + L    G
Sbjct: 515 GRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVG 561


>gi|45827802 prestin isoform c [Homo sapiens]
          Length = 516

 Score =  335 bits (860), Expect = 6e-92
 Identities = 170/476 (35%), Positives = 292/476 (61%), Gaps = 13/476 (2%)

Query: 40  SCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPI 99
           +C+   +R ++   LP T+WL  Y+ +EY+ GD++SG+  G++ +PQ +A+++LA + PI
Sbjct: 51  TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPI 110

Query: 100 YSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANS 159
           + LY+SF+  ++Y  +GTSRH+S+G F+++ LM+G V  R +         D + PG  +
Sbjct: 111 FGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVP-------DDIVIPGGVN 163

Query: 160 STLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGA 219
           +T NG+ A     RD   ++VA ++TL++G+ Q  +GV R GFV+ YL++PL+ GF   A
Sbjct: 164 AT-NGTEA-----RDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217

Query: 220 SVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKE 279
           +V + TS LK+L GV+  R+ G   VV + +++L+     NVC +    +   +LL  KE
Sbjct: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277

Query: 280 LSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQ 339
            ++R++ +L  P+P E   +V+ T +S    L + +   V G +P G +PP  P+  L  
Sbjct: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFH 337

Query: 340 RVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAAL 399
            V +DA+A+A+V  + +IS+A+  A  HGY V  NQEL+A+G CN + +    F+ S +L
Sbjct: 338 LVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSL 397

Query: 400 AKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWD 459
           ++SLV+  TG +TQL+  +++ ++LLV+LA   LF  L ++VL+ +++V+L+G   +  D
Sbjct: 398 SRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSD 457

Query: 460 LPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLAR 515
           LP  WR S  +  +W  T  + + +  + GL+  VI++LL++  RTQ   T +  R
Sbjct: 458 LPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSFHTEMTRR 513


>gi|16418413 solute carrier family 26, member 9 isoform a [Homo
           sapiens]
          Length = 791

 Score =  302 bits (773), Expect = 8e-82
 Identities = 166/525 (31%), Positives = 291/525 (55%), Gaps = 10/525 (1%)

Query: 41  CSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIY 100
           CS   ++A+V  LLP   WL +Y+ ++Y+  D++ GL  G I VPQ +A++LLA L  + 
Sbjct: 43  CSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVN 102

Query: 101 SLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSS 160
            LY+SFF  L YF +G    +  G F+++ ++VG +    LQLA    S+  +   A + 
Sbjct: 103 GLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNIC---LQLA--PESKFQVFNNATNE 157

Query: 161 TLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGAS 220
           +   +AAM     +   + V+  L  +T + Q+ +G ++ GFV+ YLS+  + GF   A 
Sbjct: 158 SYVDTAAM-----EAERLHVSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAG 212

Query: 221 VTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKEL 280
           + IL S LK++ G+ IP + GPG +V T++ + +     N+  ++ + +  A L+  KEL
Sbjct: 213 LQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKEL 272

Query: 281 SDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQR 340
           + RY H++R P+PTE++V+VVAT +S   ++ K++   + G+I  GF  P  P     + 
Sbjct: 273 NARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWKD 332

Query: 341 VALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALA 400
           +   A +LA+V+   ++++    A  HGY V +NQE++A+GC N   +F        AL+
Sbjct: 333 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 392

Query: 401 KSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDL 460
            +L     G ++Q++S+  + VV++ +L L    + L +SVL  +I V+L+ +L+++ D 
Sbjct: 393 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 452

Query: 461 PRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTA 520
             LWR S  D  +W  +  +   +S   G+  GV  S+L +  +TQ      LA++ DT 
Sbjct: 453 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 512

Query: 521 FYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD 565
            Y +   +       G+++  +  PLY+AN + F Q + + TG+D
Sbjct: 513 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMD 557



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 3/108 (2%)

Query: 587 PAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLL 646
           PA  E  G  S   A VP    FHT+++D + + F+D  G+  L  L   YG +G+ + L
Sbjct: 640 PASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFL 699

Query: 647 ACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHREL 694
                 V + +S GG   +G   + E + +F S+HDAV  A+A  R++
Sbjct: 700 VNIHAQVYNDISHGGVFEDG---SLECKHVFPSIHDAVLFAQANARDV 744


>gi|217272867 solute carrier family 26, member 9 isoform b [Homo
           sapiens]
          Length = 887

 Score =  302 bits (773), Expect = 8e-82
 Identities = 166/525 (31%), Positives = 291/525 (55%), Gaps = 10/525 (1%)

Query: 41  CSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIY 100
           CS   ++A+V  LLP   WL +Y+ ++Y+  D++ GL  G I VPQ +A++LLA L  + 
Sbjct: 43  CSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVN 102

Query: 101 SLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSS 160
            LY+SFF  L YF +G    +  G F+++ ++VG +    LQLA    S+  +   A + 
Sbjct: 103 GLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNIC---LQLA--PESKFQVFNNATNE 157

Query: 161 TLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGAS 220
           +   +AAM     +   + V+  L  +T + Q+ +G ++ GFV+ YLS+  + GF   A 
Sbjct: 158 SYVDTAAM-----EAERLHVSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAG 212

Query: 221 VTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKEL 280
           + IL S LK++ G+ IP + GPG +V T++ + +     N+  ++ + +  A L+  KEL
Sbjct: 213 LQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKEL 272

Query: 281 SDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQR 340
           + RY H++R P+PTE++V+VVAT +S   ++ K++   + G+I  GF  P  P     + 
Sbjct: 273 NARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWKD 332

Query: 341 VALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALA 400
           +   A +LA+V+   ++++    A  HGY V +NQE++A+GC N   +F        AL+
Sbjct: 333 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 392

Query: 401 KSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDL 460
            +L     G ++Q++S+  + VV++ +L L    + L +SVL  +I V+L+ +L+++ D 
Sbjct: 393 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 452

Query: 461 PRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTA 520
             LWR S  D  +W  +  +   +S   G+  GV  S+L +  +TQ      LA++ DT 
Sbjct: 453 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 512

Query: 521 FYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD 565
            Y +   +       G+++  +  PLY+AN + F Q + + TG+D
Sbjct: 513 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMD 557



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 3/108 (2%)

Query: 587 PAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLL 646
           PA  E  G  S   A VP    FHT+++D + + F+D  G+  L  L   YG +G+ + L
Sbjct: 640 PASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFL 699

Query: 647 ACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHREL 694
                 V + +S GG   +G   + E + +F S+HDAV  A+A  R++
Sbjct: 700 VNIHAQVYNDISHGGVFEDG---SLECKHVFPSIHDAVLFAQANARDV 744


>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
           sapiens]
          Length = 656

 Score =  262 bits (670), Expect = 7e-70
 Identities = 164/597 (27%), Positives = 296/597 (49%), Gaps = 18/597 (3%)

Query: 54  LPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYF 113
           LP   W   Y  +E L  D +SG+++ +  V Q +A+++L+ + P++ LY S F  +IY 
Sbjct: 32  LPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYA 91

Query: 114 LMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGR 173
           + G   HV+ G F+L  L+    V+R +       +   L   +N+S L  S   +    
Sbjct: 92  IFGMGHHVATGTFALTSLISANAVERIVP-----QNMQNLTTQSNTSVLGLSDFEMQ--- 143

Query: 174 DCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLG 233
               I VA A++ + G+ QV M VL+LG  +  +++P++     GA+  ++TSQ+K+LLG
Sbjct: 144 ---RIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLG 200

Query: 234 VRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLP 293
           +++P   GP      +  +        +  ++ S + + VL+  KEL+++++ +++V LP
Sbjct: 201 MKMPYISGPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLP 260

Query: 294 TELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAA 353
            +L++I+ A+   +   +   +G  V G IP G   P+ P   ++  V  +A  +ALV  
Sbjct: 261 VDLVLIIAASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGY 320

Query: 354 AFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQ 413
             S++LA+  A+   YS+  NQE LA G  N++ +F  C  ++AA+ ++    +TG +TQ
Sbjct: 321 VASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQ 380

Query: 414 LSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALV 473
           ++ ++S   VL+V+ A+ PL + L   VLA +IVV L+G L +  DL + W +   D  +
Sbjct: 381 VACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGI 440

Query: 474 WAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVP 533
           W  T    +  +   GLL GV+ ++  + GR  R  T  +  + +  F +  TE +    
Sbjct: 441 WVSTYVFTICFAANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEMEF-KVKTEMDSETL 499

Query: 534 EPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDL 593
           +  V++     PL + N   F   L ++   +  C          E        + G   
Sbjct: 500 QQ-VKIISINNPLVFLNAKKFYTDLMNMIQKENACNQPLDDISKCEQNTLLNSLSNGNCN 558

Query: 594 GPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCS 650
              S      P    +  +++DC+   F D +GVS L ++  D     + +LLA C+
Sbjct: 559 EEASQSC---PNEKCY--LILDCSGFTFFDYSGVSMLVEVYMDCKGRSVDVLLAHCT 610


>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
           sapiens]
          Length = 663

 Score =  262 bits (670), Expect = 7e-70
 Identities = 164/597 (27%), Positives = 296/597 (49%), Gaps = 18/597 (3%)

Query: 54  LPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYF 113
           LP   W   Y  +E L  D +SG+++ +  V Q +A+++L+ + P++ LY S F  +IY 
Sbjct: 32  LPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYA 91

Query: 114 LMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGR 173
           + G   HV+ G F+L  L+    V+R +       +   L   +N+S L  S   +    
Sbjct: 92  IFGMGHHVATGTFALTSLISANAVERIVP-----QNMQNLTTQSNTSVLGLSDFEMQ--- 143

Query: 174 DCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLG 233
               I VA A++ + G+ QV M VL+LG  +  +++P++     GA+  ++TSQ+K+LLG
Sbjct: 144 ---RIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLG 200

Query: 234 VRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLP 293
           +++P   GP      +  +        +  ++ S + + VL+  KEL+++++ +++V LP
Sbjct: 201 MKMPYISGPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLP 260

Query: 294 TELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAA 353
            +L++I+ A+   +   +   +G  V G IP G   P+ P   ++  V  +A  +ALV  
Sbjct: 261 VDLVLIIAASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGY 320

Query: 354 AFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQ 413
             S++LA+  A+   YS+  NQE LA G  N++ +F  C  ++AA+ ++    +TG +TQ
Sbjct: 321 VASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQ 380

Query: 414 LSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALV 473
           ++ ++S   VL+V+ A+ PL + L   VLA +IVV L+G L +  DL + W +   D  +
Sbjct: 381 VACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGI 440

Query: 474 WAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVP 533
           W  T    +  +   GLL GV+ ++  + GR  R  T  +  + +  F +  TE +    
Sbjct: 441 WVSTYVFTICFAANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEMEF-KVKTEMDSETL 499

Query: 534 EPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDL 593
           +  V++     PL + N   F   L ++   +  C          E        + G   
Sbjct: 500 QQ-VKIISINNPLVFLNAKKFYTDLMNMIQKENACNQPLDDISKCEQNTLLNSLSNGNCN 558

Query: 594 GPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCS 650
              S      P    +  +++DC+   F D +GVS L ++  D     + +LLA C+
Sbjct: 559 EEASQSC---PNEKCY--LILDCSGFTFFDYSGVSMLVEVYMDCKGRSVDVLLAHCT 610


>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
          Length = 563

 Score =  239 bits (609), Expect = 8e-63
 Identities = 140/387 (36%), Positives = 224/387 (57%), Gaps = 18/387 (4%)

Query: 88  IAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFD 147
           +A++LLA + P++ LYTSFF  LIY L+GT RH+S G F++L LM G  V+R        
Sbjct: 42  MAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVER-------- 93

Query: 148 PSQDGLQPGANSSTLNG-SAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAY 206
                L P      L+G     LD  R    + VA A+   +G   + M VL+LG +S +
Sbjct: 94  -----LVPEPLVGNLSGIEKEQLDAQR----VGVAAAVAFGSGALMLGMFVLQLGVLSTF 144

Query: 207 LSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVT 266
           LS+P++     GA++ +L SQL  LLG+ +PR  G   +  T  SLL    +++  ++  
Sbjct: 145 LSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTI 204

Query: 267 STVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTG 326
           S + LA+L+  KEL+ R+R RL  P+P E++++++A+++     +  R+   + G +P G
Sbjct: 205 SALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGG 264

Query: 327 FMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVL 386
           F  P +P    + R+  D++ +ALV+ A S SLA + A  + Y++ +NQE LA G  N++
Sbjct: 265 FPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLI 324

Query: 387 PAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVI 446
            +   CF  SA LA + +    G +TQL+ + S TVVL VLL L P F+ L ++VLAC+ 
Sbjct: 325 SSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACIN 384

Query: 447 VVSLRGALRKVWDLPRLWRMSPADALV 473
           + S+R    ++ +LP+LW +S  D L+
Sbjct: 385 ISSMRQVFCQMQELPQLWHISRVDFLL 411


>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
           sapiens]
          Length = 970

 Score =  234 bits (596), Expect = 3e-61
 Identities = 138/523 (26%), Positives = 265/523 (50%), Gaps = 29/523 (5%)

Query: 39  CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAG--L 96
           C CS       V  + P   W+  YR +++L GD+++G+ +G++ VPQ +  SLLA   +
Sbjct: 62  CRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLI 121

Query: 97  QPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPG 156
            P+   Y +F +++IY + G+   +S+G F L+  ++  V+               + P 
Sbjct: 122 PPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLK--------------VSPF 167

Query: 157 ANSSTLNGSAAMLDCGRDCY------AIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQP 210
            N   + GS    +     Y      ++ V    T +TG+ Q++MGVL LGF++ YL + 
Sbjct: 168 NNGQLVMGSFVKNEFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPES 227

Query: 211 LLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMV---VLTWLSLLRGAGQANVCDVVTS 267
            +  +    ++ I+ SQL  + G+ I  H GP      ++ +   L  A   ++   +T 
Sbjct: 228 AMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTV 287

Query: 268 TVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGF 327
            V L +    +   ++Y     +  P EL +I+  T++++   +      ++   IP  F
Sbjct: 288 VVALRINKCIRISFNQYP----IEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSF 343

Query: 328 MPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLP 387
           + P  P+  L+ ++ L A +L+LV++   I L +  A  H YSV +NQ+L+A+G CNV+ 
Sbjct: 344 LLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVS 403

Query: 388 AFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIV 447
           +F      + A+A+++++  +G R Q +S+V A V+LL+++ +   F+ L  +VLA +I+
Sbjct: 404 SFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIIL 463

Query: 448 VSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQR 507
            ++   L  + +LP LWR    D  +W  T ++ + +  + GL+  V+ +      R+ R
Sbjct: 464 SNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHR 523

Query: 508 PRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYAN 550
            +  LL +I +T  Y    ++  ++  PGV++F+    + + N
Sbjct: 524 AKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVN 566



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 9/114 (7%)

Query: 578 SETGVGEGGPAQGE-DLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRD 636
           S  G+ +   +QG   L P S  A+L+P+    HT+++D + + ++D+ G+  L+ +   
Sbjct: 693 SSPGLPDVAESQGRRSLIPYSD-ASLLPSV---HTIILDFSMVHYVDSRGLVVLRQICNA 748

Query: 637 YGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARAR 690
           +    I +L+A C   +     R  F   G   T    QLFLSVHDAV  A +R
Sbjct: 749 FQNANILILIAGCHSSIVRAFERNDFFDAGITKT----QLFLSVHDAVLFALSR 798


>gi|45827804 prestin isoform d [Homo sapiens]
          Length = 335

 Score =  201 bits (511), Expect = 2e-51
 Identities = 102/288 (35%), Positives = 176/288 (61%), Gaps = 13/288 (4%)

Query: 40  SCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPI 99
           +C+   +R ++   LP T+WL  Y+ +EY+ GD++SG+  G++ +PQ +A+++LA + PI
Sbjct: 51  TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPI 110

Query: 100 YSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANS 159
           + LY+SF+  ++Y  +GTSRH+S+G F+++ LM+G V  R +         D + PG  +
Sbjct: 111 FGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVP-------DDIVIPGGVN 163

Query: 160 STLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGA 219
           +T NG+ A     RD   ++VA ++TL++G+ Q  +GV R GFV+ YL++PL+ GF   A
Sbjct: 164 AT-NGTEA-----RDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAA 217

Query: 220 SVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKE 279
           +V + TS LK+L GV+  R+ G   VV + +++L+     NVC +    +   +LL  KE
Sbjct: 218 AVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKE 277

Query: 280 LSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGF 327
            ++R++ +L  P+P E   +V+ T +S    L + +   V G +P GF
Sbjct: 278 FNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGF 325


>gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
          Length = 606

 Score =  176 bits (447), Expect = 5e-44
 Identities = 142/494 (28%), Positives = 229/494 (46%), Gaps = 73/494 (14%)

Query: 45  CVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYT 104
           C  A +Q  LP   WL  Y   ++L  D ++GL +G+  +PQA+AY+ +AGL P Y LY+
Sbjct: 25  CSPAALQRRLPILAWLPSYS-LQWLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYS 83

Query: 105 SFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNG 164
           +F    +YF +GTSR V++G  +++ L+V      E                        
Sbjct: 84  AFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHE------------------------ 119

Query: 165 SAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTIL 224
                      YA+ +A     ++G  Q+ MGVLRLGF+  ++S P++ GF   A+VTI 
Sbjct: 120 ---------PAYAVLLA----FLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIG 166

Query: 225 TSQLKHLLGVR-IPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDR 283
             Q+K+LLG++ IPR       +  + + LR A +  V D V   VC+ +LL  K + D 
Sbjct: 167 FGQIKNLLGLQNIPRP----FFLQVYHTFLRIA-ETRVGDAVLGLVCMLLLLVLKLMRDH 221

Query: 284 YR--HRLRVP-------------LPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFM 328
               H    P                  LV+  A LV++  ++       + G+   G  
Sbjct: 222 VPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLP 281

Query: 329 PPQVPE------------PRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQE 376
           P ++P               ++Q +      + L+    SI++A+ FA  + Y + ANQE
Sbjct: 282 PVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQE 341

Query: 377 LLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHD 436
           LLA+G  N+L + +  +  + +  ++ V   +G  T    +V+  +VLL L  L  LF+ 
Sbjct: 342 LLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYY 401

Query: 437 LQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVIL 496
           + +S LA VI++++   L        LWR+   D L    T   C     + G+LAG ++
Sbjct: 402 IPKSALAAVIIMAV-APLFDTKIFRTLWRVKRLDLLPLCVTFLLCFW-EVQYGILAGALV 459

Query: 497 SLLSLAGRTQRPRT 510
           SLL L     RP T
Sbjct: 460 SLLMLLHSAARPET 473


>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
           sapiens]
          Length = 865

 Score =  138 bits (347), Expect = 2e-32
 Identities = 71/257 (27%), Positives = 142/257 (55%)

Query: 294 TELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAA 353
           T ++ I+  T++++   +      ++   IP  F+ P  P+  L+ ++ L A +L+LV++
Sbjct: 205 TGIIQIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSS 264

Query: 354 AFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQ 413
              I L +  A  H YSV +NQ+L+A+G CNV+ +F      + A+A+++++  +G R Q
Sbjct: 265 FLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQ 324

Query: 414 LSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALV 473
            +S+V A V+LL+++ +   F+ L  +VLA +I+ ++   L  + +LP LWR    D  +
Sbjct: 325 FASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCAL 384

Query: 474 WAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVP 533
           W  T ++ + +  + GL+  V+ +      R+ R +  LL +I +T  Y    ++  ++ 
Sbjct: 385 WMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIIT 444

Query: 534 EPGVRVFRFGGPLYYAN 550
            PGV++F+    + + N
Sbjct: 445 IPGVKIFQCCSSITFVN 461



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 40/164 (24%), Positives = 77/164 (46%), Gaps = 22/164 (13%)

Query: 39  CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAG--L 96
           C CS       +  + P   W+  YR +++L GD+++G+ +G++ VPQ +  SLLA   +
Sbjct: 62  CRCSWHRFLRCMLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLI 121

Query: 97  QPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPG 156
            P+   Y +F +++IY + G+   +S+G F L+  ++  V+               + P 
Sbjct: 122 PPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLK--------------VSPF 167

Query: 157 ANSSTLNGSAAMLDCGRDCY------AIRVATALTLMTGLYQVL 194
            N   + GS    +     Y      ++ V    T +TG+ Q++
Sbjct: 168 NNGQLVMGSFVKNEFSAPSYLMGYNKSLSVVATTTFLTGIIQII 211



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 9/114 (7%)

Query: 578 SETGVGEGGPAQGE-DLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRD 636
           S  G+ +   +QG   L P S  A+L+P+    HT+++D + + ++D+ G+  L+ +   
Sbjct: 588 SSPGLPDVAESQGRRSLIPYSD-ASLLPSV---HTIILDFSMVHYVDSRGLVVLRQICNA 643

Query: 637 YGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARAR 690
           +    I +L+A C   +     R  F   G   T    QLFLSVHDAV  A +R
Sbjct: 644 FQNANILILIAGCHSSIVRAFERNDFFDAGITKT----QLFLSVHDAVLFALSR 693


>gi|217272870 solute carrier family 26, member 9 isoform c [Homo
           sapiens]
          Length = 459

 Score =  127 bits (319), Expect = 4e-29
 Identities = 66/221 (29%), Positives = 119/221 (53%)

Query: 345 AVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLV 404
           A +LA+V+   ++++    A  HGY V +NQE++A+GC N   +F        AL+ +L 
Sbjct: 5   AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64

Query: 405 KTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLW 464
               G ++Q++S+  + VV++ +L L    + L +SVL  +I V+L+ +L+++ D   LW
Sbjct: 65  VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124

Query: 465 RMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYED 524
           R S  D  +W  +  +   +S   G+  GV  S+L +  +TQ      LA++ DT  Y +
Sbjct: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184

Query: 525 ATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLD 565
              +       G+++  +  PLY+AN + F Q + + TG+D
Sbjct: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMD 225



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 3/108 (2%)

Query: 587 PAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLL 646
           PA  E  G  S   A VP    FHT+++D + + F+D  G+  L  L   YG +G+ + L
Sbjct: 308 PASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFL 367

Query: 647 ACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHREL 694
                 V + +S GG   +G   + E + +F S+HDAV  A+A  R++
Sbjct: 368 VNIHAQVYNDISHGGVFEDG---SLECKHVFPSIHDAVLFAQANARDV 412


>gi|239746976 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
           sapiens]
          Length = 601

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 46/174 (26%), Positives = 61/174 (35%), Gaps = 16/174 (9%)

Query: 470 DALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFE 529
           D  V AG    C + ++  G   G   +          P    L   G    +    E +
Sbjct: 42  DPRVTAGALGRCQIAASAVGARGGPGPAQGPQREEEGAPGCRSLVGRGWGVGWAAVAEVQ 101

Query: 530 GLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARR-KEGGSETGVGEGGPA 588
           G V E G   F  G  L  A           + G + GC   R+ K G S+ G G    A
Sbjct: 102 GTVGERGALAFGGGRGLLAAG----------VGGAEGGCQVTRKIKRGRSKEGGGSWFGA 151

Query: 589 QGEDLGPVST----RAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYG 638
            G++ G VS         V      HT + D AP L   A  ++ LQD  R  G
Sbjct: 152 -GKETGEVSLLPFCSLGCVRDCNSQHTFLSDQAPSLKSSAIALAMLQDWCRRMG 204


>gi|169217313 PREDICTED: similar to paraneoplastic antigen MA1 [Homo
           sapiens]
          Length = 601

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 46/174 (26%), Positives = 61/174 (35%), Gaps = 16/174 (9%)

Query: 470 DALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFE 529
           D  V AG    C + ++  G   G   +          P    L   G    +    E +
Sbjct: 42  DPRVTAGALGRCQIAASAVGARGGPGPAQGPQREEEGAPGCRSLVGRGWGVGWAAVAEVQ 101

Query: 530 GLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARR-KEGGSETGVGEGGPA 588
           G V E G   F  G  L  A           + G + GC   R+ K G S+ G G    A
Sbjct: 102 GTVGERGACAFGGGRGLLAAG----------VGGAEGGCQVTRKIKRGRSKEGGGSWFGA 151

Query: 589 QGEDLGPVST----RAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYG 638
            G++ G VS         V      HT + D AP L   A  ++ LQD  R  G
Sbjct: 152 -GKETGEVSLLPFCSLGCVRDCNSQHTFLSDQAPSLKSSAIALAMLQDWCRRMG 204


>gi|223468674 carnitine palmitoyltransferase 1B isoform d [Homo
           sapiens]
          Length = 691

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 293 PTELLVIVVATLVSHFGQLHKRFG--SSVAGDIPTGFMPPQVPEPRLMQRVALDAVALAL 350
           PT  LV+++AT+ S F  +    G  S +   +P G  P Q P+ R +  +A+ +  + +
Sbjct: 59  PTSWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWV 118

Query: 351 VAAAFSISLAEMFARSHGY 369
               F     ++    HG+
Sbjct: 119 TGIFFFRQTLKLLLCYHGW 137


>gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 293 PTELLVIVVATLVSHFGQLHKRFG--SSVAGDIPTGFMPPQVPEPRLMQRVALDAVALAL 350
           PT  LV+++AT+ S F  +    G  S +   +P G  P Q P+ R +  +A+ +  + +
Sbjct: 59  PTSWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWV 118

Query: 351 VAAAFSISLAEMFARSHGY 369
               F     ++    HG+
Sbjct: 119 TGIFFFRQTLKLLLCYHGW 137


>gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo
           sapiens]
          Length = 738

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 293 PTELLVIVVATLVSHFGQLHKRFG--SSVAGDIPTGFMPPQVPEPRLMQRVALDAVALAL 350
           PT  LV+++AT+ S F  +    G  S +   +P G  P Q P+ R +  +A+ +  + +
Sbjct: 59  PTSWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWV 118

Query: 351 VAAAFSISLAEMFARSHGY 369
               F     ++    HG+
Sbjct: 119 TGIFFFRQTLKLLLCYHGW 137


>gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 293 PTELLVIVVATLVSHFGQLHKRFG--SSVAGDIPTGFMPPQVPEPRLMQRVALDAVALAL 350
           PT  LV+++AT+ S F  +    G  S +   +P G  P Q P+ R +  +A+ +  + +
Sbjct: 59  PTSWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWV 118

Query: 351 VAAAFSISLAEMFARSHGY 369
               F     ++    HG+
Sbjct: 119 TGIFFFRQTLKLLLCYHGW 137


>gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 293 PTELLVIVVATLVSHFGQLHKRFG--SSVAGDIPTGFMPPQVPEPRLMQRVALDAVALAL 350
           PT  LV+++AT+ S F  +    G  S +   +P G  P Q P+ R +  +A+ +  + +
Sbjct: 59  PTSWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWV 118

Query: 351 VAAAFSISLAEMFARSHGY 369
               F     ++    HG+
Sbjct: 119 TGIFFFRQTLKLLLCYHGW 137


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,161,251
Number of Sequences: 37866
Number of extensions: 1164350
Number of successful extensions: 3842
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3749
Number of HSP's gapped (non-prelim): 54
length of query: 701
length of database: 18,247,518
effective HSP length: 109
effective length of query: 592
effective length of database: 14,120,124
effective search space: 8359113408
effective search space used: 8359113408
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.