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Search of human proteins with 20336205
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20336205 transcriptional regulator ATRX isoform 2 [Homo
sapiens]
(2454 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 4873 0.0
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 4854 0.0
gi|168823443 RAD54-like 2 [Homo sapiens] 504 e-142
gi|216548193 RAD54-like protein [Homo sapiens] 166 2e-40
gi|216548186 RAD54-like protein [Homo sapiens] 166 2e-40
gi|4557565 excision repair cross-complementing rodent repair def... 138 6e-32
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 137 1e-31
gi|6912622 RAD54 homolog B [Homo sapiens] 137 2e-31
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 132 5e-30
gi|58331268 excision repair protein ERCC6-like [Homo sapiens] 129 5e-29
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 127 1e-28
gi|58219008 RAD26L hypothetical protein [Homo sapiens] 122 3e-27
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 120 2e-26
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 120 2e-26
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 120 2e-26
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 120 2e-26
gi|164419749 SWI/SNF-related matrix-associated actin-dependent r... 120 2e-26
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re... 119 4e-26
gi|21914927 helicase, lymphoid-specific [Homo sapiens] 119 4e-26
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 118 6e-26
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 116 2e-25
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 116 2e-25
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 116 3e-25
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 114 1e-24
gi|38708321 INO80 complex homolog 1 [Homo sapiens] 114 2e-24
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 113 2e-24
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 112 6e-24
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 112 6e-24
gi|21071044 SWI/SNF-related matrix-associated actin-dependent re... 111 8e-24
gi|87299628 biorientation of chromosomes in cell division 1-like... 110 1e-23
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 4873 bits (12639), Expect = 0.0
Identities = 2454/2454 (100%), Positives = 2454/2454 (100%)
Query: 1 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS 60
MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
Sbjct: 1 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS 60
Query: 61 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS 120
KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
Sbjct: 61 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS 120
Query: 121 LPKEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDE 180
LPKEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDE
Sbjct: 121 LPKEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDE 180
Query: 181 QCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVT 240
QCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVT
Sbjct: 181 QCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVT 240
Query: 241 ACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGS 300
ACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGS
Sbjct: 241 ACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGS 300
Query: 301 VTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSV 360
VTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSV
Sbjct: 301 VTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSV 360
Query: 361 LADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDIS 420
LADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDIS
Sbjct: 361 LADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDIS 420
Query: 421 KSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIV 480
KSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIV
Sbjct: 421 KSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIV 480
Query: 481 SVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKT 540
SVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKT
Sbjct: 481 SVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKT 540
Query: 541 TAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEH 600
TAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEH
Sbjct: 541 TAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEH 600
Query: 601 LVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKK 660
LVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKK
Sbjct: 601 LVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKK 660
Query: 661 DKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIH 720
DKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIH
Sbjct: 661 DKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIH 720
Query: 721 TNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYD 780
TNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYD
Sbjct: 721 TNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYD 780
Query: 781 SELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDD 840
SELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDD
Sbjct: 781 SELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDD 840
Query: 841 AERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRK 900
AERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRK
Sbjct: 841 AERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRK 900
Query: 901 VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF 960
VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF
Sbjct: 901 VAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDF 960
Query: 961 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1020
KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD
Sbjct: 961 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1020
Query: 1021 ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK 1080
ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK
Sbjct: 1021 ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMK 1080
Query: 1081 EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKA 1140
EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKA
Sbjct: 1081 EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKA 1140
Query: 1141 VIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSH 1200
VIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSH
Sbjct: 1141 VIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSH 1200
Query: 1201 TGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE 1260
TGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE
Sbjct: 1201 TGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE 1260
Query: 1261 GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT 1320
GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT
Sbjct: 1261 GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKT 1320
Query: 1321 KPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS 1380
KPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS
Sbjct: 1321 KPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS 1380
Query: 1381 YKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1440
YKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK
Sbjct: 1381 YKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1440
Query: 1441 KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLV 1500
KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLV
Sbjct: 1441 KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLV 1500
Query: 1501 LDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGL 1560
LDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGL
Sbjct: 1501 LDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGL 1560
Query: 1561 GKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELAT 1620
GKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELAT
Sbjct: 1561 GKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELAT 1620
Query: 1621 VKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVC 1680
VKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVC
Sbjct: 1621 VKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVC 1680
Query: 1681 DEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRN 1740
DEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRN
Sbjct: 1681 DEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRN 1740
Query: 1741 RFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVR 1800
RFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVR
Sbjct: 1741 RFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVR 1800
Query: 1801 MTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKEN 1860
MTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKEN
Sbjct: 1801 MTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKEN 1860
Query: 1861 KGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVW 1920
KGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVW
Sbjct: 1861 KGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVW 1920
Query: 1921 NSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSG 1980
NSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSG
Sbjct: 1921 NSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSG 1980
Query: 1981 KMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWL 2040
KMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWL
Sbjct: 1981 KMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWL 2040
Query: 2041 RNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDAS 2100
RNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDAS
Sbjct: 2041 RNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDAS 2100
Query: 2101 WNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERH 2160
WNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERH
Sbjct: 2101 WNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERH 2160
Query: 2161 FTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLL 2220
FTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLL
Sbjct: 2161 FTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLL 2220
Query: 2221 DHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSA 2280
DHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSA
Sbjct: 2221 DHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSA 2280
Query: 2281 MSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA 2340
MSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA
Sbjct: 2281 MSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQA 2340
Query: 2341 SQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMM 2400
SQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMM
Sbjct: 2341 SQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMM 2400
Query: 2401 PKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM 2454
PKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
Sbjct: 2401 PKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM 2454
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 4854 bits (12590), Expect = 0.0
Identities = 2454/2492 (98%), Positives = 2454/2492 (98%), Gaps = 38/2492 (1%)
Query: 1 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS 60
MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
Sbjct: 1 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS 60
Query: 61 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS 120
KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
Sbjct: 61 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS 120
Query: 121 LPK--------------------------------------EDGLHGIVSCTACGQQVNH 142
LPK EDGLHGIVSCTACGQQVNH
Sbjct: 121 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH 180
Query: 143 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC 202
FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
Sbjct: 181 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC 240
Query: 203 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV 262
KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
Sbjct: 241 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV 300
Query: 263 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI 322
DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
Sbjct: 301 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI 360
Query: 323 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM 382
ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
Sbjct: 361 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM 420
Query: 383 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT 442
DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
Sbjct: 421 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT 480
Query: 443 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS 502
EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
Sbjct: 481 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS 540
Query: 503 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI 562
SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
Sbjct: 541 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI 600
Query: 563 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK 622
KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
Sbjct: 601 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK 660
Query: 623 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK 682
TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
Sbjct: 661 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK 720
Query: 683 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK 742
QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
Sbjct: 721 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK 780
Query: 743 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR 802
RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
Sbjct: 781 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR 840
Query: 803 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT 862
IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
Sbjct: 841 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT 900
Query: 863 IMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDG 922
IMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
Sbjct: 901 IMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDG 960
Query: 923 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP 982
LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
Sbjct: 961 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP 1020
Query: 983 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK 1042
EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
Sbjct: 1021 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK 1080
Query: 1043 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL 1102
KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
Sbjct: 1081 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL 1140
Query: 1103 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI 1162
SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
Sbjct: 1141 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI 1200
Query: 1163 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1222
TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
Sbjct: 1201 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1260
Query: 1223 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1282
DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
Sbjct: 1261 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1320
Query: 1283 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE 1342
NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
Sbjct: 1321 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE 1380
Query: 1343 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1402
DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
Sbjct: 1381 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1440
Query: 1403 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE 1462
NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
Sbjct: 1441 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE 1500
Query: 1463 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL 1522
EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
Sbjct: 1501 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL 1560
Query: 1523 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS 1582
KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
Sbjct: 1561 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS 1620
Query: 1583 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI 1642
TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
Sbjct: 1621 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI 1680
Query: 1643 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS 1702
IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
Sbjct: 1681 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS 1740
Query: 1703 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM 1762
RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
Sbjct: 1741 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM 1800
Query: 1763 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN 1822
KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
Sbjct: 1801 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN 1860
Query: 1823 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM 1882
SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
Sbjct: 1861 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM 1920
Query: 1883 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS 1942
SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
Sbjct: 1921 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS 1980
Query: 1943 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF 2002
LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
Sbjct: 1981 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF 2040
Query: 2003 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE 2062
SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
Sbjct: 2041 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE 2100
Query: 2063 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV 2122
EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
Sbjct: 2101 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV 2160
Query: 2123 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS 2182
YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
Sbjct: 2161 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS 2220
Query: 2183 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA 2242
EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
Sbjct: 2221 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA 2280
Query: 2243 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN 2302
EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
Sbjct: 2281 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN 2340
Query: 2303 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM 2362
SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
Sbjct: 2341 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM 2400
Query: 2363 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY 2422
LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
Sbjct: 2401 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY 2460
Query: 2423 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM 2454
QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
Sbjct: 2461 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM 2492
>gi|168823443 RAD54-like 2 [Homo sapiens]
Length = 1467
Score = 504 bits (1297), Expect = e-142
Identities = 377/1162 (32%), Positives = 575/1162 (49%), Gaps = 194/1162 (16%)
Query: 1209 DEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQ 1268
DE+ S S P D + ++ E +++ +EE + DE+ DD EG G +
Sbjct: 3 DESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRD---DEEDLLDDPSLEGM--CGTE 57
Query: 1269 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV 1328
+ + D + + S + S SE S++ R RH+ E ++K+ + H
Sbjct: 58 HAQLGEDGQQPPRCTSTTSSQSEPSEQLR------RHQGKNLASEDPKKKRAQKPSHMR- 110
Query: 1329 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL-------------E 1375
RN RK+ ED Q V++ + E E+R R +K E
Sbjct: 111 --RNIRKLLRED------QLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEE 162
Query: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
R+ + R+ QE ++ S SE+E+ ++E E EE
Sbjct: 163 IALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSGEE------------- 209
Query: 1436 GKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPI 1495
D ++ ++ E++E E E+ + +V+ DA
Sbjct: 210 ------------DTLHIVDSSESVSEDDE------EEEKGGTHVNDVLNQRDA------- 244
Query: 1496 TTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILA 1555
+++++ + +E V + + +KPHQ+ G++F++D ES+++ K S G GCILA
Sbjct: 245 LGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILA 304
Query: 1556 HCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKW---QEGLKDDEK 1612
H MGLGKTLQV+SF+ +L T L + P+NT NW+ EF W E L D K
Sbjct: 305 HSMGLGKTLQVISFID--VLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNK 362
Query: 1613 LEVSELATVK---------RPQERSYMLQRWQEDGGVMIIGYEMYRNL------AQGRNV 1657
E + K R+ ++ W +GGV+++GYEMYR L A GR
Sbjct: 363 PEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPK 422
Query: 1658 KSRK-----------------LKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSI 1700
K++K + F KAL PGPD V+CDEGH +KN ++ S+A+ +I
Sbjct: 423 KTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNI 482
Query: 1701 RSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVR 1760
RSRRR++LTG PLQNNLIEY CMV+F++ + LG+ +EF N F PI NGQC DST DVR
Sbjct: 483 RSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVR 542
Query: 1761 VMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVG 1820
+M+ R+H+L+ +L G VQR+ +T L LP K E V+ VR++ IQ LY ++D G
Sbjct: 543 LMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCG 602
Query: 1821 NNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDET 1880
++ G G + F + +IW HP L E E +A++ D
Sbjct: 603 SS-----GWLGLNPLKAFCVCCKIWNHPDVLY-------------EALQKESLANEQDLD 644
Query: 1881 SMSLSSDDYTKK-KKKGKKGKKDSSSSGSGSDNDVEVIKVWNSR-SRGGGEGNVDETGNN 1938
L S + + +G KGK + S+ S + NS+ +G G E GNN
Sbjct: 645 VEELGSAGTSARCPPQGTKGKGEDSTLASSMG------EATNSKFLQGVGFNPFQERGNN 698
Query: 1939 PSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDK 1998
+W KD +T+ VLE+S KMVLLF ++ + ++GDK
Sbjct: 699 -------------------IVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDK 739
Query: 1999 VLVFSQSLISLDLIEDFL---ELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQ 2055
+LVFSQSL +L LIE+FL E+ TE +G KW+RNI Y+RLDGST A
Sbjct: 740 ILVFSQSLSTLALIEEFLGKREVPCPPGTEG-------QGAQKWVRNISYFRLDGSTPAF 792
Query: 2056 SRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYR 2115
R++ +FND +N+ LF++ST+AG LG+NL+ ANRV++FDASWNP +D Q++ RVYR
Sbjct: 793 ERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYR 852
Query: 2116 FGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPD 2175
+GQ KP Y+YR +A T+E KIYDRQ++KQ +S RVVD +FT E+ L F
Sbjct: 853 YGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHF--- 909
Query: 2176 LLDDPNSEKKKKRDTPMLP------KDTILAELLQIHKEHIVGYH--EHDSLLDHKEEEE 2227
+K P + K+++L +L + H++ EH+SLL ++++ +
Sbjct: 910 ---------VEKEPAPQVSLNVKGIKESVL-QLACLKYPHLITKEPFEHESLLLNRKDHK 959
Query: 2228 LTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLE 2287
LT+ E+KAA YE +K+ ++ + P+ P S S T ++ A S + +
Sbjct: 960 LTKAEKKAAKKSYEEDKR-TSVPYTRPSYAQYYPASDQSLT--------SIPAFSQRNWQ 1010
Query: 2288 DLINQGREKVVEATNSVTAVRI 2309
+ +G EK V + V + I
Sbjct: 1011 PTL-KGDEKPVASVRPVQSTPI 1031
Score = 37.4 bits (85), Expect = 0.18
Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 30/151 (19%)
Query: 1392 VQEDSSSENKSNSEEEEEEKEEEEEEEEEE-------EEEEEDENDDSKSPGKGRKKIRK 1444
+ ++S+S + + + + E ++ EEEEEEEE ++EED DD G + +
Sbjct: 1 MSDESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRDDEEDLLDDPSLEGMCGTEHAQ 60
Query: 1445 ILKD------------------DKLRTETQNALKEEEERRKRIAEREREREKLREVIEIE 1486
+ +D ++LR L E+ ++KR + R +R+++ +
Sbjct: 61 LGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLRED 120
Query: 1487 DASPTKCPITTKLVLDEDEETKEPLVQVHRN 1517
P TK E+ E ++ L Q ++
Sbjct: 121 QLEP-----VTKAAQQEELERRKRLEQQRKD 146
>gi|216548193 RAD54-like protein [Homo sapiens]
Length = 747
Score = 166 bits (421), Expect = 2e-40
Identities = 117/375 (31%), Positives = 189/375 (50%), Gaps = 30/375 (8%)
Query: 1494 PITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGS-GC 1552
P++ L D+E V V + L+PHQ +GV+F+W+C +++ PGS GC
Sbjct: 125 PLSAHDQLKLDKEKLPVHVVVDPILSKVLRPHQREGVKFLWECVT-----SRRIPGSHGC 179
Query: 1553 ILAHCMGLGKTLQVVSFLHTVLLCD---KLDFSTALVVCPLNTALNWMNEFEKWQEGLKD 1609
I+A MGLGKTLQ ++ + T+L K + A+VV P + NW NE KW G
Sbjct: 180 IMADEMGLGKTLQCITLMWTLLRQSPECKPEIDKAVVVSPSSLVKNWYNEVGKWLGGRIQ 239
Query: 1610 DEKLEVSELATVKRPQERSYMLQRWQE-DGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNK 1668
++ + + E +M QR ++II YE +R L G + K
Sbjct: 240 PLAIDGGSKDEIDQKLE-GFMNQRGARVSSPILIISYETFR-LHVG----------VLQK 287
Query: 1669 ALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIK 1728
V V+CDEGH LKN + +A++S+ + RR++++GTP+QN+L+EY +V+F+
Sbjct: 288 GSVG----LVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVN 343
Query: 1729 ENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKF 1788
+LG+ EF+ F PI G+ A ++ D ++ ++R L ++ C+ R+ L+K+
Sbjct: 344 SGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKY 403
Query: 1789 LPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHP 1848
LP K E V+ R+T +Q +LY+ +L E GK L ++ HP
Sbjct: 404 LPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLE---GKMSVSSLSSITSLKKLCNHP 460
Query: 1849 WCLQLDYISKENKGY 1863
L D +E G+
Sbjct: 461 -ALIYDKCVEEEDGF 474
Score = 130 bits (327), Expect = 2e-29
Identities = 80/212 (37%), Positives = 119/212 (56%), Gaps = 25/212 (11%)
Query: 1979 SGKMVLLFEILRMAEE-IGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEG 2037
SGKM++L IL + DKV++ S +LDL E
Sbjct: 495 SGKMLVLDYILAVTRSRSSDKVVLVSNYTQTLDLFEKLCRA------------------- 535
Query: 2038 KWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIF 2097
R Y RLDG+ + + R K E FN ++ +F++S+KAG G+NL+ ANR+++F
Sbjct: 536 ---RRYLYVRLDGTMSIKKRAKVVERFNSPSSP-DFVFMLSSKAGGCGLNLIGANRLVMF 591
Query: 2098 DASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQ- 2156
D WNP+ D Q++ RV+R GQ K Y+YR L+ GT+E+KI+ RQ K++LS VVD++Q
Sbjct: 592 DPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDEEQD 651
Query: 2157 VERHFTMNELTELYTFEPDLLDDPNSEKKKKR 2188
VERHF++ EL EL+ + L D + +R
Sbjct: 652 VERHFSLGELKELFILDEASLSDTHDRLHCRR 683
>gi|216548186 RAD54-like protein [Homo sapiens]
Length = 747
Score = 166 bits (421), Expect = 2e-40
Identities = 117/375 (31%), Positives = 189/375 (50%), Gaps = 30/375 (8%)
Query: 1494 PITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGS-GC 1552
P++ L D+E V V + L+PHQ +GV+F+W+C +++ PGS GC
Sbjct: 125 PLSAHDQLKLDKEKLPVHVVVDPILSKVLRPHQREGVKFLWECVT-----SRRIPGSHGC 179
Query: 1553 ILAHCMGLGKTLQVVSFLHTVLLCD---KLDFSTALVVCPLNTALNWMNEFEKWQEGLKD 1609
I+A MGLGKTLQ ++ + T+L K + A+VV P + NW NE KW G
Sbjct: 180 IMADEMGLGKTLQCITLMWTLLRQSPECKPEIDKAVVVSPSSLVKNWYNEVGKWLGGRIQ 239
Query: 1610 DEKLEVSELATVKRPQERSYMLQRWQE-DGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNK 1668
++ + + E +M QR ++II YE +R L G + K
Sbjct: 240 PLAIDGGSKDEIDQKLE-GFMNQRGARVSSPILIISYETFR-LHVG----------VLQK 287
Query: 1669 ALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIK 1728
V V+CDEGH LKN + +A++S+ + RR++++GTP+QN+L+EY +V+F+
Sbjct: 288 GSVG----LVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVN 343
Query: 1729 ENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKF 1788
+LG+ EF+ F PI G+ A ++ D ++ ++R L ++ C+ R+ L+K+
Sbjct: 344 SGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKY 403
Query: 1789 LPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHP 1848
LP K E V+ R+T +Q +LY+ +L E GK L ++ HP
Sbjct: 404 LPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLE---GKMSVSSLSSITSLKKLCNHP 460
Query: 1849 WCLQLDYISKENKGY 1863
L D +E G+
Sbjct: 461 -ALIYDKCVEEEDGF 474
Score = 130 bits (327), Expect = 2e-29
Identities = 80/212 (37%), Positives = 119/212 (56%), Gaps = 25/212 (11%)
Query: 1979 SGKMVLLFEILRMAEE-IGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEG 2037
SGKM++L IL + DKV++ S +LDL E
Sbjct: 495 SGKMLVLDYILAVTRSRSSDKVVLVSNYTQTLDLFEKLCRA------------------- 535
Query: 2038 KWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIF 2097
R Y RLDG+ + + R K E FN ++ +F++S+KAG G+NL+ ANR+++F
Sbjct: 536 ---RRYLYVRLDGTMSIKKRAKVVERFNSPSSP-DFVFMLSSKAGGCGLNLIGANRLVMF 591
Query: 2098 DASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQ- 2156
D WNP+ D Q++ RV+R GQ K Y+YR L+ GT+E+KI+ RQ K++LS VVD++Q
Sbjct: 592 DPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDEEQD 651
Query: 2157 VERHFTMNELTELYTFEPDLLDDPNSEKKKKR 2188
VERHF++ EL EL+ + L D + +R
Sbjct: 652 VERHFSLGELKELFILDEASLSDTHDRLHCRR 683
>gi|4557565 excision repair cross-complementing rodent repair
deficiency, complementation group 6 [Homo sapiens]
Length = 1493
Score = 138 bits (348), Expect = 6e-32
Identities = 77/200 (38%), Positives = 117/200 (58%), Gaps = 25/200 (12%)
Query: 1977 EHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGE 2036
+ SGKM+++ +L++ + G +VL+FSQS LD++E FL
Sbjct: 836 KRSGKMIVVESLLKIWHKQGQRVLLFSQSRQMLDILEVFLRA------------------ 877
Query: 2037 GKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVII 2096
+ Y ++DG+TT SR+ +N++T++ +F+++T+ G LG+NL ANRV+I
Sbjct: 878 ----QKYTYLKMDGTTTIASRQPLITRYNEDTSIF--VFLLTTRVGGLGVNLTGANRVVI 931
Query: 2097 FDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQ 2156
+D WNPS D Q+ R +R GQ K V VYR L GT+E+KIY RQ+ KQ L+ RV+ +
Sbjct: 932 YDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPK 991
Query: 2157 VERHFTMNELTELYTF-EPD 2175
R F N+L EL+T PD
Sbjct: 992 QRRFFKSNDLYELFTLTSPD 1011
Score = 128 bits (321), Expect = 8e-29
Identities = 124/508 (24%), Positives = 222/508 (43%), Gaps = 87/508 (17%)
Query: 1359 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQ-------------EDSSSENKSNSE 1405
+++ +P ++ ++ EE + + +K ++R ++ Q D E + +SE
Sbjct: 309 QNKNKPNKKARVLSKKEERLKKHIKKLQKRALQFQGKVGLPKARRPWESDMRPEAEGDSE 368
Query: 1406 EEEEEKEEEEEEEEEEEEEEEDENDDSKSPG---------KGRKKIRKI----LKDDKLR 1452
EE E EEEEEEE++E E D G KG K+ +K+ + DD
Sbjct: 369 GEESEYFPTEEEEEEEDDEVEGAEADLSGDGTDYELKPLPKGGKRQKKVPVQEIDDDFFP 428
Query: 1453 TETQNALK----------EEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLD 1502
+ + A + R + + + +++LR ++ K +L L+
Sbjct: 429 SSGEEAEAASVGEGGGGGRKVGRYRDDGDEDYYKQRLRRWNKLRLQDKEK-----RLKLE 483
Query: 1503 EDEETKEPLV----QVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCM 1558
+D E + +V + KL +Q GV+++W+ C+ +G IL M
Sbjct: 484 DDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQ---------AGGILGDEM 534
Query: 1559 GLGKTLQVVSFLHTVLLCDKL----------DFSTALVVCPLNTALNWMNEFEKWQEGLK 1608
GLGKT+Q+++FL L K+ ++VCP W+ EF W +
Sbjct: 535 GLGKTIQIIAFL-AGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQWVKEFHTWWPPFR 593
Query: 1609 DDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNK 1668
+ E + +E+ +++ G++I Y R +
Sbjct: 594 ---VAILHETGSYTHKKEK--LIRDVAHCHGILITSYSYIR---------------LMQD 633
Query: 1669 ALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIK 1728
+ +V+ DEGH ++N +AV+ A R+ RIIL+G+P+QNNL E + +FI
Sbjct: 634 DISRYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIF 693
Query: 1729 ENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQR--KDYTALT 1786
LG++ F +F PI G ++++ V V+ K A +L + + + R K ++
Sbjct: 694 PGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMS 753
Query: 1787 KFLPPKHEYVLAVRMTSIQCKLYQYYLD 1814
LP K+E VL R+T Q K+YQ ++D
Sbjct: 754 LSLPDKNEQVLFCRLTDEQHKVYQNFVD 781
Score = 35.8 bits (81), Expect = 0.53
Identities = 46/192 (23%), Positives = 82/192 (42%), Gaps = 40/192 (20%)
Query: 1254 SDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGE 1313
SD PE G+++E P +EE + + + ++++ S DG
Sbjct: 357 SDMRPEAEGDSEGEESEYFPTEEEEEEEDDEVEGAEADLS----------------GDG- 399
Query: 1314 SGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAE 1373
+ E K PK G+ ++KV ++ +D F SG E + S E R +
Sbjct: 400 TDYELKPLPKG-----GKRQKKVPVQEIDDDFFPSSGEEAEAA-SVGEGGGGGRKVGRYR 453
Query: 1374 LEENQRSYKQKKKR-RRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1432
+ ++ YKQ+ +R ++++Q ++EK + E++ EE + E DE
Sbjct: 454 DDGDEDYYKQRLRRWNKLRLQ--------------DKEKRLKLEDDSEESDAEFDEG--F 497
Query: 1433 KSPGKGRKKIRK 1444
K PG KK+ K
Sbjct: 498 KVPGFLFKKLFK 509
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 137 bits (346), Expect = 1e-31
Identities = 163/815 (20%), Positives = 287/815 (35%), Gaps = 45/815 (5%)
Query: 637 SNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEM 696
SN+ + N + + D NSSD + N N + S D + +SDE
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDES 498
Query: 697 L-----AILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD 751
+ K S+SDT+ ++ + N D K D GK K SS S S
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND---DNDKSDSGKGKSDSSDSDSS 555
Query: 752 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS 811
+ S+ SS + S+S + DS+ S S + N+ D
Sbjct: 556 DSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS---------NSSDSSD 606
Query: 812 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP 871
S D S D+ K+ + E S D++ K + +S++ + + D++
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD---SSNSS 663
Query: 872 KKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL 931
+S S+D D S + S +S +++ + S ++ D S +
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSS----DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Query: 932 KKDQSDETSED--DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 989
+ SD S + D S ++ +SSD ++ +
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Query: 990 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEK-STGKGDSCDSSEDKKSKNGA 1048
+ ++D S S + SD ++ S+ DS +SS+ S N +
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 1049 YGREKKRCKLLGKS-SRKRQDCS----SSDTEKYSMKEDGCNSSDKRLKRIELRERRNLS 1103
+ S S R D S SSD+ S D +SSD E + S
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN----ESSNSSDSS 895
Query: 1104 SKRNTKEIQS--GSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQAD 1161
N+ + S S+SSD+ +SS + + SS +S +S +D
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Query: 1162 ITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVD 1221
++SS S D +S SSD ++ SS + S D + S + D
Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD----SSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 1222 DDDDDN--DPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAK 1279
D N D N + ++ SSD SSD + ++ + + +
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 1280 NQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSE 1339
+ +S+S SE S + + S S + + + + SS+
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131
Query: 1340 DSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSE 1399
S+ SD S S + SES D + S+ ++ ++ S + S S
Sbjct: 1132 SSDSSDSSNSSDSSDSSESSDSS-DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190
Query: 1400 NKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKS 1434
+ S+S + + + + + + + D +D S S
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1225
Score = 137 bits (344), Expect = 2e-31
Identities = 152/791 (19%), Positives = 270/791 (34%), Gaps = 55/791 (6%)
Query: 660 KDKRNSSDS-AIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINE 718
K K +SSDS + D+ + S S++ D NS SD + + S S S SSD+ +
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD-SDSSDSSDSDSSDSSNSS 602
Query: 719 IHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSN 778
++ D + D KS + SD D+K S +S S + S+SSN
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS-SDSSN 661
Query: 779 YDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSS 838
+ + S S ++ + ++ D S + S D+ + +S +S
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 839 D--DAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSL 896
+ D++ ++ S+ + D++ +S S+D D + S +S
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS- 780
Query: 897 EVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKK 956
S + SD + D SD + D S
Sbjct: 781 -------NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 957 PSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTS 1016
S SSDG++ + + + +++S
Sbjct: 834 DSSNSSD----SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Query: 1017 KKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEK 1076
D + DS +SS+ S N + E SS SSD+
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Query: 1077 YSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSS 1136
S D NSSD + SS N+ + S+SSD+ +SS+ + SS
Sbjct: 950 SSNSSDSSNSSDS--------SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Query: 1137 KKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLV 1196
+S +S +D ++SS S D +S S + + +
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 1197 LSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSD- 1255
SS + S D + S + D D N ++ + SSD SSD
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD----------SSDSSDSSDS 1111
Query: 1256 -DEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGES 1314
D + + ++ ++ + NS SDS ES + S S
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS-----------SDSSDSS 1160
Query: 1315 GEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED--EQRPRTRSAKKA 1372
+ + + + SS+ S+ SD +S S + S+S D + + S+ +
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Query: 1373 ELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN--- 1429
+ ++ S + + S S N S+S + + + + +E + + + N
Sbjct: 1221 DSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280
Query: 1430 --DDSKSPGKG 1438
DS S +G
Sbjct: 1281 NGSDSDSDSEG 1291
Score = 127 bits (319), Expect = 1e-28
Identities = 164/864 (18%), Positives = 298/864 (34%), Gaps = 35/864 (4%)
Query: 432 DSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIF 491
D + M + P +N + + + N+ E D S +D
Sbjct: 456 DDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDD-- 513
Query: 492 ENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVK 551
+ ++ + +S D G+G++G + +S S K S D+ S ++
Sbjct: 514 -DSDSTSDTNNS-DSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571
Query: 552 LTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLE 611
S S+S +D + D D S + + ++SD+ +++
Sbjct: 572 SDSNSSSDSDSSDSDSSD-SSDSDSSDSSNSSDSSDSSD-SSDSSDSSDSSDSKSDSSKS 629
Query: 612 ESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAID 671
ESD S + + ++ + NSD + S D +SSDS+
Sbjct: 630 ESDSSDSDSKSDSS---DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686
Query: 672 NPKPNKLPKSKQSETVDQN--SDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDL 729
+ + S SE+ D + SDSD + S S S SS++ + +N D
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746
Query: 730 KTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKS 789
+ D S++S S + S+ SS S + S S+ S S
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806
Query: 790 MSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERET 849
++ ++ N+ D +S D S D+ + S +GS D+ + +
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD---SSDGSDSDSSNRSDSS- 862
Query: 850 FSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSK 909
+S++ + D++ ++S S+D D + + + + S
Sbjct: 863 -NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921
Query: 910 HLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQ 969
+ SD + D SD ++ D S + SD
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS-SDSNSSDSSDSS 980
Query: 970 QYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKS 1029
SSD ++ + + ++D S S + SD ++ S
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 1030 TGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDK 1089
DS DSS+ S + + + SS SSD+ + S D NSSD
Sbjct: 1041 ----DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096
Query: 1090 RLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRN 1149
+ + + S ++ + S SS++ +SS+ + SS + +
Sbjct: 1097 S----DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 1150 SLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGD 1209
S +S +D + SS S D NS S + + + SS + S D
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212
Query: 1210 EALSKSVPVTVDDDD--DDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGK 1267
+ S + D D D N+ + + ++ SSD SSD T
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS--------TSD 1264
Query: 1268 QNEENPGDEEAKNQVNSESDSDSE 1291
N+E+ ++ N N+ SDSDS+
Sbjct: 1265 SNDESDSQSKSGNGNNNGSDSDSD 1288
Score = 125 bits (315), Expect = 4e-28
Identities = 164/861 (19%), Positives = 287/861 (33%), Gaps = 43/861 (4%)
Query: 502 SSVDHQGDGSSGTEQEVESSS---VKLNIS-SKDNRGGIKSKTTAKVTKELYVKLTPVSL 557
SS + G+ + +E + SSS N SKDN G SK +
Sbjct: 467 SSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD---------- 516
Query: 558 SNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRR 617
S S +D + +G N K + ++SD++ + S + SD
Sbjct: 517 STSDTNNSD-----SNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571
Query: 618 SPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNK 677
S ++ + +S+SD + + S D +SSDS D+ K
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 678 LPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDD 737
S S++ +SDS+ + S S +SS+ +D ++ + + + D
Sbjct: 632 --DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Query: 738 KGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAAR 797
+S+ SD + S S + S+SSN + S S +
Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749
Query: 798 TTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQE--GSSDDAERKQERETFSSAEG 855
+ ++ D +S D S D+ N S + SSD ++ ++ +S++
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 856 -----TVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKH 910
+ D D++ +S S+D D + S + R + S
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Query: 911 LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQ 970
+ SD E D SD ++ D S + SD +
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS-----DSSNSSDSSDSSNSSDSS 924
Query: 971 YESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKST 1030
S+S + + + S D + + SD + S+
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSD-SSNSS 983
Query: 1031 GKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKR 1090
DS DSS+ S + + + SS +SSD+ S D +SSD
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS- 1042
Query: 1091 LKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNS 1150
+ + S ++ S SSD+ +SS+ + SS+ +S
Sbjct: 1043 ------SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096
Query: 1151 LRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDE 1210
+S +D + SS S D NS S + + N SS + S D
Sbjct: 1097 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDS 1156
Query: 1211 ALSKSVPVTVD--DDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQ 1268
+ S + D D D +D N + ++ SSD SSD +
Sbjct: 1157 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1216
Query: 1269 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV 1328
++ + + + + ++ES S+ S + + S + + + K
Sbjct: 1217 SDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG 1276
Query: 1329 KGRNRRKVSSEDSEDSDFQES 1349
G N S DSE SD S
Sbjct: 1277 NGNNNGSDSDSDSEGSDSNHS 1297
Score = 117 bits (293), Expect = 1e-25
Identities = 164/851 (19%), Positives = 303/851 (35%), Gaps = 83/851 (9%)
Query: 383 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT 442
D N + N + D ++ + KG K D S S++ S DS + +
Sbjct: 520 DTNNSDSNGNGNNGNDDNDKSDSGKG-------KSDSSDSDSSDSSNSSDSSDSSDSDSS 572
Query: 443 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS 502
+ ++ S + SD + + +N+S+ D S SS D ++ ++ +
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD----SSDSSDSSDSSDSSDSKSDSSK 628
Query: 503 SVDHQGDGSSGTEQ-EVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSP 561
S D S ++ + SS N S D+ S ++ + + S S+
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS-----SDSSSSSDS 683
Query: 562 IKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRV 621
+D + + +S + + +S N + +++ S + SD S
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743
Query: 622 KTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKS 681
+ ++++ + +SD + + S D NSSDS N N S
Sbjct: 744 SDS-----SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS---NDSSNSSDSS 795
Query: 682 KQSETVDQNSDSDEMLAILKEVSRMSHSS-SSDTDINEIHTNHKTLYDLKTQAGKDDKGK 740
S + D ++ SD + S S+SS SS++ + +N D + D
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855
Query: 741 RKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTK 800
R S++ SD S+ SS S + S SN S S + + +
Sbjct: 856 SNRSDSSNSSD-------SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908
Query: 801 KRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKD 860
++ D +S D S DN + S + SSD ++ ++ +S++ + D
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD-SSDSSDSSNSSDSSNSSDSSNSSD 967
Query: 861 TTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQ 920
++ D +S S+D D + S +S + + + S +
Sbjct: 968 SSDSNSSD----SSDSSNSSDSSDSSDSSDSSDSS----DSSNSSDSSDSSDSSDSSNSS 1019
Query: 921 DGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEK 980
D S+ ++ D SD + D S ++ + SSD ++
Sbjct: 1020 DS-SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 981 LPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSE 1040
E ++D S S + SD ++ S DS DSS+
Sbjct: 1079 SDSSE---------------SSDSSDSSNSSDSSDSSDSSDSSDSSDSS----DSSDSSD 1119
Query: 1041 DKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERR 1100
S + + + SS SSD+ S D +SSD +
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS-------SDSS 1172
Query: 1101 NLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA 1160
+ S N+ + S SSD+ +SS+ + SS +S +S +
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS------------DSSDSSDSSDSS 1220
Query: 1161 DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTV 1220
D SS SSD D +++S SSD +++ S + S DE+ S+S
Sbjct: 1221 D--SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG 1278
Query: 1221 DDDDDDNDPEN 1231
+++ D+D ++
Sbjct: 1279 NNNGSDSDSDS 1289
Score = 103 bits (258), Expect = 2e-21
Identities = 143/708 (20%), Positives = 252/708 (35%), Gaps = 56/708 (7%)
Query: 764 IISKKKRQTQSE---SSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSS--EDEKHS 818
I SK+ ++E + D+ L+ S S GA + + +D ++ +D ++
Sbjct: 217 INSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNN 276
Query: 819 KKGMDNQGH--KNLKTSQEGSSDDAERKQERETFSSAEGTVDKD-TTIMELRDRLPKKQQ 875
KG + Q H ++ S G + D++ + E VD D T+ E +
Sbjct: 277 SKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDN 336
Query: 876 ASASTDGVDKLSGKEQSFTSLEVRKVAET------KEKSKHLK---------TKTCKKVQ 920
S + KL+ +E + K +ET ++K +K TK K
Sbjct: 337 GSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGN 396
Query: 921 DGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEK 980
+G D + + + + ++ + + G +K +P + KV +S+SDG +
Sbjct: 397 EGKEDKGQHGMILGKGNVKTQGEVVNIE-GPGQKSEPGN---KVGHSNTGSDSNSDGYDS 452
Query: 981 LP-EREEICHFPKGIKQIKNGTTDGEKKS---KKIRDKTSKKKDELSDYAEKSTGKG--- 1033
+ + + NG D +S R S DE D S KG
Sbjct: 453 YDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAED 512
Query: 1034 DSCDSSEDKKSK----NGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNS-SD 1088
D DS+ D + NG G + GK D SSD+ S D +S S
Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS 572
Query: 1089 KRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKR 1148
+ + SS + + S+SSD+ +SS+ + SS K+ K +
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 1149 NSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLS--SHTGFCQS 1206
+S + +K +D SS SSD D +S SSD +++ S S++
Sbjct: 633 SS-DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 1207 SGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTG 1266
S D + S + D D D+ + + + +N S D S+ + + +
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 1267 KQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHK 1326
+ + D NS SDS +S + + +S + +
Sbjct: 752 SSDSSDSSDSS-----NSSDSSDSSDSSD---------SSDSSNSSDSNDSSNSSDSSDS 797
Query: 1327 EVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKK 1386
+ S DS DS +S S + S S D S + + S
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857
Query: 1387 RRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKS 1434
R DSS + S++ + + + E + + + DS S
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Score = 102 bits (255), Expect = 4e-21
Identities = 136/741 (18%), Positives = 261/741 (35%), Gaps = 52/741 (7%)
Query: 739 GKRKRKSSTSGSDFDTKKGKSAKSSIISK-KKRQTQSESSNYDSELEKEIKSMSKIGAAR 797
G + + SG D D + G SS SK ++ Q + ++DS + + S SK
Sbjct: 250 GADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQN--SDSKEYYDP 307
Query: 798 TTKKRIPNTKDFDSSEDEKHSKKGM-DNQGHKNLKTSQEGSSDDAERKQERETFSSAEGT 856
K+ N D D + + + G+ ++ G + ++ +Q+ + +++R + R T S
Sbjct: 308 EGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHA 367
Query: 857 VDKDTTI-MELR-----DRLPKKQQASASTDGVDK-----LSGKEQSFTSLEVRKVAETK 905
V K +E++ +R K+ + DK + GK T EV +
Sbjct: 368 VGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPG 427
Query: 906 EKSKH-LKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKV 964
+KS+ K D SD + + D+S + + + G ++ SD
Sbjct: 428 QKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSS 487
Query: 965 -----IKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKK 1019
++ ++ + K E ++ NG + D K
Sbjct: 488 RGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547
Query: 1020 DELSDYAEKSTGKGDSCDSSE-DKKSKNGAYGREKKRCKLLGKSSRKRQDCS-SSDTEKY 1077
D + S+ DS DSS+ D N + + S D S SSD+
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607
Query: 1078 SMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSK 1137
S D +SSD + + + + SS ++K S S+SSD+ ++S+ + SS
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667
Query: 1138 KKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVL 1197
+S +S +D + SS+S D +S SSD
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD---------- 717
Query: 1198 SSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDE 1257
SS++ S + S D D +D N + ++ SSD SSD
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS---DSSDSSNSSDSSDSSDSS 774
Query: 1258 PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEE 1317
+ N+ + + + + +S+S + S+ S +S +
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS----------------DSSDSSDS 818
Query: 1318 KKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEEN 1377
+ + + SS+ S+ SD + S+ + S+ + + + +
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878
Query: 1378 QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGK 1437
+ DSS+ + S+S + + + + E + +D+S S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 1438 GRKKIRKILKDDKLRTETQNA 1458
D +++ N+
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNS 959
Score = 100 bits (248), Expect = 2e-20
Identities = 129/715 (18%), Positives = 252/715 (35%), Gaps = 39/715 (5%)
Query: 416 KKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKS-TGGEHKKSDRKEEPQYEPANTSED 474
K D SKSE+ S S+ N ++ S + SD + +++S D
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682
Query: 475 LDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRG 534
S SS + E+ +++ S D S+ + +SS+ + S ++
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 535 GIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQE 594
S ++ + + S S++ +D + D S N
Sbjct: 743 SSDSSDSSNSSDS-----SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 595 NSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLS 654
++ ++ ++ S + SD S ++ ++++ +SNS + + + S
Sbjct: 798 SNSSDSSNSSDSS---DSSDSSDSDSSNSSDSSNSSDSSD-SSNSSDSSDSSDSSDGSDS 853
Query: 655 VPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDT 714
+ D NSSDS+ + N S S++ + ++ SD + S S S SSD+
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS-----SDSSNSSDSDSSDS 908
Query: 715 DINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQS 774
+ ++ D + D S++S S + S+ SS S + S
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968
Query: 775 ESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQ 834
SN + S S + + ++ + S D S ++ N S
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 835 EGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFT 894
SSD ++ ++ S++ + D++ +S S+D D + S +
Sbjct: 1029 N-SSDSSDSSDSSDSSDSSDSSDSSDSS---------NSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 895 SLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEK 954
S + + +++ + S + D SD ++ D SD ++ D S ++
Sbjct: 1079 S-DSSESSDSSDSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 955 KKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDK 1014
+ SSD ++ + + ++D S
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 1015 TSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDT 1074
S + SD ++ S+ DS DSS+ S + + E SS SSD+
Sbjct: 1197 DSSDSSDSSDSSD-SSDSSDSSDSSDSSDSSDSSDSNE---------SSDSSDSSDSSDS 1246
Query: 1075 EKYSMKEDGCNSSDKRLKRIELRERRNLS--SKRNTKEIQSGSSSSDAEESSEDN 1127
S D +SSD + + ++ S N + S S SD+ S+ D+
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 85.1 bits (209), Expect = 8e-16
Identities = 122/710 (17%), Positives = 232/710 (32%), Gaps = 17/710 (2%)
Query: 340 TDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDA 399
+ NS SS + + S +D K E D + D+ + + +
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657
Query: 400 KFETKARKGEKPCALEKKDISKSE--AKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKK 457
+ + + + D S S + S S+ + + ++ ++ S +
Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717
Query: 458 SDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQE 517
S + +N+S+ D S SS D ++ ++ SS SS +
Sbjct: 718 SSNSNSSDSDSSNSSDSSD----SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 518 VESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGY 577
+SS + S D+ S ++ + + S +S ++ + D
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 578 KSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTS 637
S + + + SD++ ++ S + SD S + + + +S
Sbjct: 834 DSSNSSDSSDSSD-SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 638 NSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEML 697
+S + N + + S D NSSDS+ + + S S + D + SD
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS-- 950
Query: 698 AILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKG 757
S S+SS S + +N D + D S +S S +
Sbjct: 951 ---SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 758 KSAKSSIISKKK-RQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEK 816
S+ SS S S+SSN + S S + + N+ D S D
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 817 HSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQA 876
S D+ + S + SSD + ++ S++ + D++ +
Sbjct: 1068 DSSDSSDSSDSSDSSESSD-SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 877 SASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS 936
S S+D D S S S + + +++ + S + D SD ++ D S
Sbjct: 1127 SDSSDSSDS-SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS-SDSSDSSNSSDSS 1184
Query: 937 DETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQ 996
D + D S ++ SSD ++ E
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244
Query: 997 IKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKN 1046
+ ++D S D TS DE ++ G + DS D + +
Sbjct: 1245 DSSNSSDSSDSSDS-SDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1293
Score = 71.2 bits (173), Expect = 1e-11
Identities = 160/931 (17%), Positives = 298/931 (32%), Gaps = 104/931 (11%)
Query: 42 QNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDE 101
Q D S SN + NS+ + SSS S S SK + DD+ +
Sbjct: 461 QGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSD 520
Query: 102 TVNEDA----SNENSENDITMQSLPKEDGLHGIVSCTA-CGQQVNHFQKDSIYRHPSLQV 156
T N D+ +N N +ND + K D S ++ + DS + S
Sbjct: 521 TNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS--- 577
Query: 157 LICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELS 216
SD S DSD D ++ N + S
Sbjct: 578 -----------SDSDSSDSDSSDSSDSDSSDSSN---------------------SSDSS 605
Query: 217 TIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSR 276
D ++ D + +S ++ + + K DS SN +S
Sbjct: 606 DSSDSSDS-----------SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS--SDSSD 652
Query: 277 FSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFL 336
S SSN + D S S + S + + +++ + NSS
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS--------SNSSDSSDSSDSSNSS----- 699
Query: 337 KQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKV 396
+++D+S+ S + + S +D ++ + D ++ + D+ + ++
Sbjct: 700 -ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 397 IDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHK 456
D+ + + + + D S S N ++ S +
Sbjct: 759 SDS--SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 457 KSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQ 516
SD ++ S D S SS D ++ + S+ D S +
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876
Query: 517 EVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDG 576
S S N SS + S ++ + + SNS +D E D
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS----SDSSESSNSSDN 932
Query: 577 YKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVT 636
S + + ++ ++ ++ S + SD S ++ ++++ +
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 637 SNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEM 696
+SD + + S D NSSDS+ + N S S++ D + SD
Sbjct: 993 DSSDSSDSSNSSDSSDSS---DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Query: 697 LAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKK 756
+ S S SS +D ++ + + ++ D S+ SD
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 757 GKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEK 816
S S S+SS+ + S S + + ++ D S D
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 817 HSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQA 876
S D+ + S + SSD ++ ++ S++ + D++ +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSD-SSDSSDSSDSSDSSDSSDSSDSSDSS---------DSSDS 1219
Query: 877 SASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS 936
S S+D D E S +S +++ + S + D SD D+S
Sbjct: 1220 SDSSDSSDSSDSNESSDSS----DSSDSSDSSNSSDSSDSSDSSDSTSD------SNDES 1269
Query: 937 DETSE--------DDKKQSKKGTEEKKKPSD 959
D S+ D +G++ SD
Sbjct: 1270 DSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
Score = 66.2 bits (160), Expect = 4e-10
Identities = 146/843 (17%), Positives = 280/843 (33%), Gaps = 52/843 (6%)
Query: 25 SSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGS-------- 76
+SE +SS + N + K +G+GS+S E+ + TS + S S+G+
Sbjct: 478 NSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDN 537
Query: 77 --SRSKRKPSIVTKYVESDDEKPLD-DETVNEDASNENSENDITMQSLPKEDGLHGIVSC 133
S S + S + SD D ++ + D+S+ NS +D D S
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS-DSS 596
Query: 134 TACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLIC 193
+ + DS S K+ SD DS N
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656
Query: 194 CDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLL 253
D N+ + + S+ D +N D + NS +
Sbjct: 657 SD-SSNSSNSSDSSDSSDSSDSSSSSDSSNS--------SDSSDSSDSSNSSESSDSSDS 707
Query: 254 QQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKE 313
+ DS SN +S S SSN + D S S + S +
Sbjct: 708 SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS--SNSS 765
Query: 314 MIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEE 373
+ +++ + NSS ++D+S+ S+++ + S +D + +
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN-SSDSSDSSDSSDSDSSNSS 824
Query: 374 DLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKS----------- 422
D ++ + D+ N ++ D + + + + + D S S
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 423 --EAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDM--D 478
E+ S DS + + ++ ++ S+ + + + +N+S+ +
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 479 IVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKS 538
S SS D + +++ SS + D S + S S + SS + S
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004
Query: 539 KTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDN 598
++ + S S+ +D + D S + + + +
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 599 EHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVR 658
+ ++ S + SD S ++ ++++ + +SD + + S
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESS--DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 659 KKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINE 718
D +SSDS+ + N S SE+ D + SD S SSD+ +
Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS----------SDSSDSSDSSDSS 1172
Query: 719 IHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSN 778
++ D + D S +S S + S+ SS S + S SN
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232
Query: 779 YDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSS-EDEKHSKKGMDNQGHKNLKTSQEGS 837
S+ S ++ ++ + DS+ E + SK G N + + EGS
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGS 1292
Query: 838 SDD 840
+
Sbjct: 1293 DSN 1295
Score = 63.5 bits (153), Expect = 2e-09
Identities = 132/742 (17%), Positives = 263/742 (35%), Gaps = 117/742 (15%)
Query: 738 KGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAAR 797
+G R R+ +T D +G +K + + K T S +N + +E G
Sbjct: 63 EGDRGRQENTQ--DGHKGEGNGSKWAEVGGKSFSTYSTLANEEGNIE---------GWNG 111
Query: 798 TTKKRIPNTKDFDSSEDEKHSKKGM-------DNQGHKNLKTSQEGSSDDAERKQERETF 850
T K D ++E + G+ DN G N +++ G++D + T
Sbjct: 112 DTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATN-RSNTNGNTD-------KNTQ 163
Query: 851 SSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKL---SGKEQSFTSLEVRKVAETKEK 907
+ G + + +++ P+ ++ STD D++ S + + TS ++ +
Sbjct: 164 NGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNG 223
Query: 908 SKHLKTKTCKKVQDGLSDI----AEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKK 963
+K + GL + + +D+ + + +D+ +++ G + + +
Sbjct: 224 TKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQ 283
Query: 964 VIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELS 1023
E ++SS E + P+G K+ + DG+K SK + +D S
Sbjct: 284 DHGKEDDHDSSIGQNSDSKEYYD----PEG-KEDPHNEVDGDKTSKSEENSAGIPEDNGS 338
Query: 1024 DYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSS-SDTEKYSMKED 1082
E + + E K+ +N ++ +GKS K + S + KE
Sbjct: 339 QRIEDT----QKLNHRESKRVENRI--TKESETHAVGKSQDKGIEIKGPSSGNRNITKEV 392
Query: 1083 GCNSSDKRLKRIELRERRNLSSKRNTK-EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAV 1141
G + K K + + K N K + + + ++S NK T S +
Sbjct: 393 GKGNEGKEDKG----QHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNS- 447
Query: 1142 IVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHT 1201
+S K Q D +SS +DD NS + +S + S ++
Sbjct: 448 ----DGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDA--------SYNS 495
Query: 1202 GFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEG 1261
+ +G+ + SK DDD D N +SD +G+ ++ ++
Sbjct: 496 DESKDNGNGSDSKGAE---DDDSDSTSDTN---------------NSDSNGNGNNGNDDN 537
Query: 1262 KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1321
K + + + D ++ + NS SDS +S SD S + +
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS--------------SDSNSSSDSDSS 583
Query: 1322 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY 1381
+ + S DS+ SD S S + S+S D S K++ +++
Sbjct: 584 DSDSSD----------SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD- 632
Query: 1382 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1441
DS S++ S+ + + + + D +D S S
Sbjct: 633 -----------SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Query: 1442 IRKILKDDKLRTETQNALKEEE 1463
D +++ N+ + +
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSD 703
Score = 52.4 bits (124), Expect = 6e-06
Identities = 123/728 (16%), Positives = 242/728 (33%), Gaps = 52/728 (7%)
Query: 7 SESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTS 66
S+SK ++ + + S +S +++S + ++D S S ++SD ++S +S
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS-SNSSNSSDSSDSSDSSDSS 678
Query: 67 SSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKEDG 126
SS S +S S S ++ +S D D + + D+SN NS + + S D
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSD-SDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 127 LHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCA 186
+ S + + DS S S D S SD D
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSD------------SSDSSDSSDSSDSS----- 780
Query: 187 EGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVF 246
N+ + + S D +N D + +S
Sbjct: 781 ------------NSSDSNDSSNSSDSSDSSNSSDSSNS--------SDSSDSSDSSDSDS 820
Query: 247 ENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYS 306
N N S S+ S SSN + D S S + S
Sbjct: 821 SNSSD--SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878
Query: 307 ALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKK 366
+ ++N + S ++D+S+ S+++ +
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 367 AHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDIS----KS 422
++ + D + + D+ N ++ D+ + + + D S S
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 423 EAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSV 482
++ S DS + + + + + SD + ++ S D S
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 483 PSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTA 542
SS D ++ +++ SS + SS + +SS + S D+ S ++
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 543 KVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLV 602
+ + S S+ +D D +S + + + ++
Sbjct: 1119 DSSNS-----SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173
Query: 603 ENEVSLLLEESDLR-RSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKD 661
++ S + SD S ++ ++++ + +SD + + S +
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233
Query: 662 KRNSSDSAIDNPKPNKLPKSKQSETVDQNSDS-DEMLAILKEVSRMSHSSSSDTDINEIH 720
+SSDS+ + N S S++ D SDS DE + K + ++ S SD+D
Sbjct: 1234 SSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1293
Query: 721 TNHKTLYD 728
+NH T D
Sbjct: 1294 SNHSTSDD 1301
Score = 41.2 bits (95), Expect = 0.013
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Query: 1854 DYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDND 1913
D S ++ DS + +SDS ++S S S D + K K + DSS S S SD+
Sbjct: 584 DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSS 643
Query: 1914 VEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+S S + + +N S S +S +SSS+ SS + D
Sbjct: 644 DSN----SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Score = 40.4 bits (93), Expect = 0.022
Identities = 28/106 (26%), Positives = 44/106 (41%)
Query: 1857 SKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEV 1916
SK + + DS D SDS +++ S SSD+ DSS S SD+
Sbjct: 622 SKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Query: 1917 IKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+S S + + ++ S S + S ++ SSN +S D
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727
Score = 38.9 bits (89), Expect = 0.063
Identities = 26/106 (24%), Positives = 42/106 (39%)
Query: 1857 SKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEV 1916
S ++ D DS D +SDS ++S S S + + +SS S S +
Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953
Query: 1917 IKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
NS + D ++ S S +S +S S+ SS + D
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Score = 38.5 bits (88), Expect = 0.082
Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 6/109 (5%)
Query: 1854 DYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDND 1913
D S ++ D DS D SDS ++S S SSD DSS S SD+
Sbjct: 568 DSDSSDSNSSSDSDSSD----SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 1914 VEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ K + + D + +N S S +S +S+S+ SS + D
Sbjct: 624 SDSSK--SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670
Score = 38.1 bits (87), Expect = 0.11
Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 2/108 (1%)
Query: 1857 SKENKGYFDEDSMDEFIASDSDETSMSLSSD--DYTKKKKKGKKGKKDSSSSGSGSDNDV 1914
S N+ DS D +SDSD + S SSD D + + +S+ S S N
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 1915 EVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ +S + + D + ++ S +S +S+S+ SS + D
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Score = 37.7 bits (86), Expect = 0.14
Identities = 27/109 (24%), Positives = 44/109 (40%)
Query: 1854 DYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDND 1913
D S ++ + +S D ++ SD + S SSD DSS S + SD+
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 1914 VEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+S S + N ++ S S +S +S S+ SS + D
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Score = 37.4 bits (85), Expect = 0.18
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS S + SD+ NS
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS-------NSSDS 809
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ D +N S S +S +S+S+ SS + D
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Score = 37.4 bits (85), Expect = 0.18
Identities = 26/96 (27%), Positives = 40/96 (41%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS +S S +S D + +SS S SD+ +S S
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S +S +S S+ SS + D
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Score = 36.6 bits (83), Expect = 0.31
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS S SD+ +S S
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S ES +S S+ SS + D
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD 1164
Score = 36.2 bits (82), Expect = 0.41
Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Query: 1859 ENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSS-SSGSGSDNDVEVI 1917
++KG D+DS ++SD + +D K G KGK DSS S S S N +
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG-KGKSDSSDSDSSDSSNSSDSS 564
Query: 1918 KVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+S S + ++ ++ S +S +S+S+ SS + D
Sbjct: 565 DSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD 609
Score = 36.2 bits (82), Expect = 0.41
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 1/115 (0%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS S SD+ +S S
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1223
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSG 1980
+ + ++ S S +S +S S+ SS + D D ++D++ +G
Sbjct: 1224 DSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG 1278
Score = 35.8 bits (81), Expect = 0.53
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 8/111 (7%)
Query: 1860 NKGYFDEDSMD----EFIASDSDETSMSLSSDDY----TKKKKKGKKGKKDSSSSGSGSD 1911
N G D D D + +SDSD + S SSD + DSS S S
Sbjct: 531 NNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 590
Query: 1912 NDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+D + NS + D + ++ S K + SK+ S S+ S D
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641
Score = 35.8 bits (81), Expect = 0.53
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 7/96 (7%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++S S S ++ K DSS S S +D NS S
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD-------NSDSSD 658
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ ++ S S S +S+S+ SS + D
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694
Score = 35.8 bits (81), Expect = 0.53
Identities = 24/91 (26%), Positives = 40/91 (43%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS + +SDS +S S +S D + +SS S + SD+ +S S
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD 846
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPS 1957
+G+ ++ N S + S ++ SSN S
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Score = 35.4 bits (80), Expect = 0.70
Identities = 29/107 (27%), Positives = 41/107 (38%), Gaps = 1/107 (0%)
Query: 1857 SKENKGYFDEDSM-DEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVE 1915
SK D DS D ++ SD + S SSD DSS S S SD+
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686
Query: 1916 VIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+S S E + ++ S + S + SS + SS + D
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733
Score = 35.4 bits (80), Expect = 0.70
Identities = 25/92 (27%), Positives = 39/92 (42%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++S S S + + DSS S + SD+ +S S
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSS 1958
+ + +N S S +S +S S+ SS
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Score = 35.4 bits (80), Expect = 0.70
Identities = 28/97 (28%), Positives = 40/97 (41%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS S SD+ +S S
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S +S +S S+ SS + D
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Score = 35.0 bits (79), Expect = 0.91
Identities = 29/107 (27%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
Query: 1857 SKENKGYFDE-DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVE 1915
S +N D +S D +SDS +S S +S D + DSS S + SD
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD---- 984
Query: 1916 VIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+S S + + +N S S +S +S+S+ SS + D
Sbjct: 985 -----SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026
Score = 35.0 bits (79), Expect = 0.91
Identities = 25/96 (26%), Positives = 40/96 (41%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
+S D +SDS +++ S SSD DSS S S++ +S S
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S +S +S S+ SS + D
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053
Score = 34.7 bits (78), Expect = 1.2
Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 1/102 (0%)
Query: 1857 SKENKGYFDEDSMDEFIASDSDETS-MSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVE 1915
S ++ DS D +SDS ++S S SSD DSS S SD+
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 1916 VIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPS 1957
+S S + + +N S S +S + SSN S
Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824
Score = 34.7 bits (78), Expect = 1.2
Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 7/96 (7%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
+S D +SDS ++ S SSD DSS S SD +S S
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS-------DSDSSN 857
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S SN SS + D
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Score = 34.7 bits (78), Expect = 1.2
Identities = 24/96 (25%), Positives = 41/96 (42%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS + +SDS +++ S +S D + DSS+S SD+ +S S
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ ++ S S S +S+S+ SS + D
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967
Score = 34.3 bits (77), Expect = 1.6
Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKK-DSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S S D + + DSS S + SD+ +S S
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S +S +S S+ SS + D
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSD 1146
Score = 33.9 bits (76), Expect = 2.0
Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1857 SKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEV 1916
S ++ +S D +SDSD + + SSD + DSS S + SD+
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSS 608
Query: 1917 IKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+S S + D + + S +SK+ SS + SS + D
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSS--DSDSKSDSSDSNSSDSSD 652
Score = 33.9 bits (76), Expect = 2.0
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 2/98 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSD--DYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRS 1924
DS D +SDS S SD D K DSS + SD+ +S S
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671
Query: 1925 RGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S +S +S S+ SS + D
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSD 709
Score = 33.9 bits (76), Expect = 2.0
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS +S S +S D + + SS S SD+ + NS S
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS-DSSDSSNSNSSD 725
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPS 1957
N ++ ++ + S + S +++SS+ S
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Score = 33.9 bits (76), Expect = 2.0
Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 3/101 (2%)
Query: 1857 SKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEV 1916
S ++ DS + +SDS +S S S D + + DSS+S SD+
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874
Query: 1917 IKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPS 1957
+S S + N ++ S S +S ++ SSN S
Sbjct: 875 N---SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Score = 33.9 bits (76), Expect = 2.0
Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 7/96 (7%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D SDSD ++ S SS+ DSS S +++ NS
Sbjct: 843 DSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS-------NSSDSS 895
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ D ++ S S +S +S S+ SS + D
Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Score = 33.9 bits (76), Expect = 2.0
Identities = 25/96 (26%), Positives = 38/96 (39%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
+S D +SDS +S S S+ DSS S SD+ +S S
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S +S +S S+ SS + D
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Score = 33.9 bits (76), Expect = 2.0
Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETS-MSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS+S S++ +S S
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S +S +S S+ SS + D
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Score = 33.9 bits (76), Expect = 2.0
Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++S S +S D DSS S SD+ +S S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSD--SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S+S+ SS + D
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131
Score = 33.9 bits (76), Expect = 2.0
Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++S S S D + DSS S SD+ +S S
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSD--SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S S+ SS + D
Sbjct: 1183 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1218
Score = 33.5 bits (75), Expect = 2.6
Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 1/96 (1%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++ S + K DS+SS S SDN +S S
Sbjct: 609 DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS-SDNSDSSDSSNSSNSSD 667
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S S+ SS + D
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703
Score = 33.5 bits (75), Expect = 2.6
Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 8/96 (8%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS + +SDS ++S S S D + DSS+S S SD+D +S S
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS-SDSD-------SSNSSD 733
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S S+ SS + D
Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769
Score = 33.5 bits (75), Expect = 2.6
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS + +SDS ++S S SSD + DSS+S SD+ +S S
Sbjct: 694 DSSNSSESSDSSDSSDSDSSD--SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + +N S S +S +S S+ SS + D
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Score = 33.5 bits (75), Expect = 2.6
Identities = 24/96 (25%), Positives = 41/96 (42%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +S+S ++S S S + + DSS+S SD+ +S S
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S S +S+S+ SS + D
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038
Score = 33.5 bits (75), Expect = 2.6
Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 4/100 (4%)
Query: 1867 DSMDEFIASDSDETS----MSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNS 1922
DS D +SDS ++S S SSD DSS S SD+ +S
Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1055
Query: 1923 RSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
S + + ++ S S +S +S S+ SS + D
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095
Score = 33.5 bits (75), Expect = 2.6
Identities = 26/96 (27%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++S S S D DSS S SD+ +S S
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S+S+ SS + D
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188
Score = 33.1 bits (74), Expect = 3.5
Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 1865 DEDSMDEFIASDS-DETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSR 1923
D +S D SDS D ++ S SSD DSS+S SD+ +S
Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703
Query: 1924 SRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
S + + ++ ++ + + +S +S S+ SS + D
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Score = 33.1 bits (74), Expect = 3.5
Identities = 22/91 (24%), Positives = 36/91 (39%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SD ++ S SD +SS S SD++ +S S
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPS 1957
+ + ++ N+ S S ++ SSN S
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930
Score = 33.1 bits (74), Expect = 3.5
Identities = 24/96 (25%), Positives = 40/96 (41%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS + +SDS ++S S S D + + SS+ S SD+ +S S
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S S +S S+ SS + D
Sbjct: 920 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Score = 33.1 bits (74), Expect = 3.5
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 1/107 (0%)
Query: 1857 SKENKGYFDEDSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVE 1915
S ++ DS D +SDS ++S S SSD DSS S + SD+
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Query: 1916 VIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+S S + + ++ S S S +S S+ SS + D
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Score = 33.1 bits (74), Expect = 3.5
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS S SD+ +S S
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S S+ SS + D
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128
Score = 33.1 bits (74), Expect = 3.5
Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++S S S D DSS S SD+ +S S
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSD--SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S S+ SS + D
Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158
Score = 33.1 bits (74), Expect = 3.5
Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS S SD+ +S S
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S + +S +S S+ SS + D
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD 1251
Score = 32.7 bits (73), Expect = 4.5
Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Query: 1868 SMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGG 1927
S D +SDS ++S S +S + + DSS S + + +D + +S
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739
Query: 1928 GEGNVDET-GNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ D + +N S S +S +S S+ SS + D
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Score = 32.7 bits (73), Expect = 4.5
Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
+S D +SDSD + S SS+ + DSS S + SD+ +S S
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSN--SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S SN SS + D
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793
Score = 32.7 bits (73), Expect = 4.5
Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS +S S +S D DSS S SD+ +S S
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSD--SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S ES +S S+ SS + D
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD 1098
Score = 32.7 bits (73), Expect = 4.5
Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 4/100 (4%)
Query: 1867 DSMDEFIASDS----DETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNS 1922
DS D +SDS D ++ S SSD DSS S + SD+ +S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 1923 RSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
S + + ++ S S +S +S S+ SS + D
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110
Score = 32.7 bits (73), Expect = 4.5
Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 4/100 (4%)
Query: 1867 DSMDEFIASDSDETSMSL----SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNS 1922
DS D +SDS ++S S SSD DSS S + SD+ +S
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 1923 RSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
S + + ++ S S +S +S S+ SS + D
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176
Score = 32.7 bits (73), Expect = 4.5
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS S + SD+ +S S
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S S +S S+ SS + D
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Score = 32.7 bits (73), Expect = 4.5
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS +S S SSD DSS S SD+ +S S
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S S+ SS + D
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1206
Score = 32.7 bits (73), Expect = 4.5
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD +SS S SD+ +S S
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S SN SS + D
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239
Score = 32.7 bits (73), Expect = 4.5
Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++S S S D DSS S SD+ +S S
Sbjct: 1152 DSSDSSDSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S S+ SS + D
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245
Score = 32.3 bits (72), Expect = 5.9
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 4/95 (4%)
Query: 1865 DEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRS 1924
DE + ++ S+SD S S Y + K DS G+ D+ NS S
Sbjct: 469 DESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSK--GAEDDDSDSTSDTNNSDS 526
Query: 1925 RGGGEGNVDETGNNPSVSLKLEESKATS--SSNPS 1957
G G D+ + S K + S + S SSN S
Sbjct: 527 NGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSS 561
Score = 32.3 bits (72), Expect = 5.9
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 1857 SKENKGYFDE-DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVE 1915
S +N D +S + +SDS ++S S SS D DSS+S SD+
Sbjct: 650 SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD--SSNSSDSSDSSDSSNSSESSDSSDS 707
Query: 1916 VIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ S + D +N S S S +S S+ SS + D
Sbjct: 708 SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754
Score = 32.3 bits (72), Expect = 5.9
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 1/97 (1%)
Query: 1867 DSMDEFIASDSDETSMSL-SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSR 1925
DS D +SDS ++S S SSD DSS S SD+ +S S
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100
Query: 1926 GGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S S +S S+ SS + D
Sbjct: 1101 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Score = 32.3 bits (72), Expect = 5.9
Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 2/96 (2%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS ++S S S D DSS S SD+ +S S
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSD--SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1191
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ + ++ S S +S +S S+ SS + D
Sbjct: 1192 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227
Score = 32.0 bits (71), Expect = 7.7
Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 9/92 (9%)
Query: 1867 DSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRG 1926
DS D +SDS+++S S S D DSS S SD+D +S S
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSD--SSNSSDSSNSSDSSDSSDSSDSD-------SSNSSD 825
Query: 1927 GGEGNVDETGNNPSVSLKLEESKATSSSNPSS 1958
+ +N S S +S S S+ S+
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN 857
Score = 32.0 bits (71), Expect = 7.7
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 11/100 (11%)
Query: 1867 DSMDEFIASDSDETSMSL----SSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNS 1922
DS D +SDS E+S S SSD +SS S + SD+ NS
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS-------NS 965
Query: 1923 RSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPD 1962
+ +N S S +S +S S+ SS + D
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
>gi|6912622 RAD54 homolog B [Homo sapiens]
Length = 910
Score = 137 bits (344), Expect = 2e-31
Identities = 99/313 (31%), Positives = 161/313 (51%), Gaps = 38/313 (12%)
Query: 1510 PLVQVHRN--MVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVV 1567
PLV V + +V L+PHQ +G+ F+++C V + + G ILA MGLGKTLQ +
Sbjct: 282 PLVDVVIDPYLVYHLRPHQKEGIIFLYEC----VMGMRMNGRCGAILADEMGLGKTLQCI 337
Query: 1568 SFLHTVLLCD-----KLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVK 1622
S + T L C K L+V P + NW EF+KW E++++ +
Sbjct: 338 SLIWT-LQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWL----GSERIKIFTVDQDH 392
Query: 1623 RPQERSYMLQRWQEDGGVMIIGYEMY-RNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCD 1681
+ +E + V+II YEM R+L Q +N+K D ++CD
Sbjct: 393 KVEEFIKSIFY-----SVLIISYEMLLRSLDQIKNIKF----------------DLLICD 431
Query: 1682 EGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNR 1741
EGH LKN A + A+ S+ +RIILTGTP+QN+L E+ +++F+ +LGS+ +R
Sbjct: 432 EGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKI 491
Query: 1742 FINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRM 1801
+ PI + ++ + + ++RA L + + R+ + K+LPPK E V+ R
Sbjct: 492 YEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRP 551
Query: 1802 TSIQCKLYQYYLD 1814
++Q +LY+ L+
Sbjct: 552 GALQIELYRKLLN 564
Score = 117 bits (292), Expect = 2e-25
Identities = 82/266 (30%), Positives = 138/266 (51%), Gaps = 40/266 (15%)
Query: 1930 GNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVT--DADAEVL----EHSGKMV 1983
G + + N+P + + K SS+ + YK ++ AD L + SGK+
Sbjct: 586 GALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQ 645
Query: 1984 LLFEILRMAEEIG--DKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLR 2041
+L ++L + E+ +KV++ S +L+++++ + K G
Sbjct: 646 VLSKLLAVIHELRPTEKVVLVSNYTQTLNILQE-----------------VCKRHG---- 684
Query: 2042 NIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASW 2101
Y RLDG T R++ + FN + + +F++S+KAG +G+NL+ + +I++D W
Sbjct: 685 -YAYTRLDGQTPISQRQQIVDGFNSQHS-SFFIFLLSSKAGGVGLNLIGGSHLILYDIDW 742
Query: 2102 NPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERH- 2160
NP+ DIQ++ RV+R GQ PV++YR L GT+E+KIY RQ++KQ L VVD + H
Sbjct: 743 NPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHI 802
Query: 2161 -FTMNELTELYTFEP-------DLLD 2178
F++ EL L+T DLLD
Sbjct: 803 QFSVEELKNLFTLHESSDCVTHDLLD 828
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 132 bits (331), Expect = 5e-30
Identities = 175/771 (22%), Positives = 322/771 (41%), Gaps = 114/771 (14%)
Query: 1088 DKRLKRIELRERRNLSSKRNTKEIQSGSSSSDA----EESSEDNKKKKQRTSSKKKAVIV 1143
++R +R E + R ++S K+++ S+ + ++ S +K+K+ ++
Sbjct: 180 EERARREEQAKLRRIASTM-AKDVRQFWSNVEKVVQFKQQSRLEEKRKKALDLHLDFIVG 238
Query: 1144 KEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGF 1203
+ +K + L + + + + + SS +G S+ P + L G
Sbjct: 239 QTEKYSDLLSQSLNQPLTSSKAGSSPC-------LGSSSAASSPPPPASR---LDDEDGD 288
Query: 1204 CQSSGDEALSKSVPVTVDDDDDDNDPEN--------RIAKKMLLEEIKANLS-------- 1247
Q DE + V++ + ND E R ++ LEE+ +L
Sbjct: 289 FQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLEGPS 348
Query: 1248 ------SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSES---DSDSEESKKPRY 1298
S D + D PEEG + Q E A Q N + D D EE
Sbjct: 349 SPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEE------ 402
Query: 1299 RHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSES 1358
T ++ E+ +E+ T E ++++G + E SE + E + E + +
Sbjct: 403 --------FTANEEEAEDEEDTIAAE-EQLEGEVDHAM--ELSELAREGELSMEELLQQY 451
Query: 1359 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV----QEDSSSENKSNSEEEEEEKEEE 1414
P + S++ + +E + + ++ QEDSSS++ S + E+E++E
Sbjct: 452 AGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEH 511
Query: 1415 EEEEEEE-----EEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEE-ERRKR 1468
EEEE EE E +E++D++S + ++ +DD E A EE+ E
Sbjct: 512 SEEEETSGSSASEESESEESEDAQSQSQADEEE----EDDDFGVEYLLARDEEQSEADAG 567
Query: 1469 IAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVD 1528
L EI D + + K + K P+ + R + + + +D
Sbjct: 568 SGPPTPGPTTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQLREYQHIGLD 627
Query: 1529 GVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVC 1588
+ M++ KK G ILA MGLGKT+Q +S L L C+K ++ L++
Sbjct: 628 WLVTMYE---------KKLNG---ILADEMGLGKTIQTISLL-AHLACEKGNWGPHLIIV 674
Query: 1589 PLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGG--VMIIGYE 1646
P + LNW E ++W K L +ER Q W + V I Y+
Sbjct: 675 PTSVMLNWEMELKRWCPSFKI--------LTYYGAQKERKLKRQGWTKPNAFHVCITSYK 726
Query: 1647 MYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRI 1706
+ Q K+ + +++ DE +KN S +++ + S+RR+
Sbjct: 727 LVLQDHQAFRRKNWR---------------YLILDEAQNIKNFKSQRWQSLLNFNSQRRL 771
Query: 1707 ILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRA 1766
+LTGTPLQN+L+E +++F+ ++ S +EF+ F NP+ G S + ++K+
Sbjct: 772 LLTGTPLQNSLMELWSLMHFLMPHVFQSHREFKEWFSNPL-TGMIEGSQEYNEGLVKR-- 828
Query: 1767 HILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLT 1817
L+++L + R+ + K +P K+E+V+ R++ Q LY ++ T
Sbjct: 829 --LHKVLRPFLLRRVKVDVEKQMPKKYEHVIRCRLSKRQRCLYDDFMAQTT 877
Score = 105 bits (263), Expect = 4e-22
Identities = 95/374 (25%), Positives = 167/374 (44%), Gaps = 67/374 (17%)
Query: 1980 GKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKW 2039
GK+ L +LR + G +VL+F+Q LD++E FL Y G
Sbjct: 2043 GKLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLT---------------YHGHL-- 2085
Query: 2040 LRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDA 2099
Y RLDGST + R+ E FN + + FI+ST++G +G+NL A+ V+ +D+
Sbjct: 2086 -----YLRLDGSTRVEQRQALMERFNADKRIF--CFILSTRSGGVGVNLTGADTVVFYDS 2138
Query: 2100 SWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQ-VE 2158
WNP+ D Q+ R +R GQT+ V++YR +++ T+E+ I + K+ L ++
Sbjct: 2139 DWNPTMDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTT 2198
Query: 2159 RHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDS 2218
+F + EL+ L++P+S P P++ E + + HI+ +
Sbjct: 2199 AYFKQQTIRELFDMP---LEEPSSS-----SVPSAPEEE--EETVASKQTHIL----EQA 2244
Query: 2219 LLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGAL 2278
L ++EE++ A + +AE+ FN G P G
Sbjct: 2245 LCRAEDEEDI------RAATQAKAEQVAELAEFNENDG--------------FPAGEGEE 2284
Query: 2279 SAMSNQQLEDLINQGRE--KVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALAL 2336
+ + E++ +E +VE + ++ LE + V +E + +E QV+A
Sbjct: 2285 AGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEA--- 2341
Query: 2337 SRQASQELDVKRRE 2350
A ++LD + E
Sbjct: 2342 ---ARKDLDQAKEE 2352
Score = 38.1 bits (87), Expect = 0.11
Identities = 65/368 (17%), Positives = 145/368 (39%), Gaps = 40/368 (10%)
Query: 709 SSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAK-SSIISK 767
+S+ D+ + +N + + K Q+ ++K ++K+ DF G++ K S ++S+
Sbjct: 195 ASTMAKDVRQFWSNVEKVVQFKQQSRLEEK---RKKALDLHLDFIV--GQTEKYSDLLSQ 249
Query: 768 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH 827
Q + S S +G++ P D + + ++ +
Sbjct: 250 SLNQPLTSSKAGSSPC---------LGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDE 300
Query: 828 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRL---PKKQQASASTDGVD 884
+ ++ ++ +DAE ++ EG + + + L +L P + S+ D
Sbjct: 301 ETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSD 360
Query: 885 KLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD- 943
G E+ E +V E K + + + D E+F ++ E ED
Sbjct: 361 TRDGPEEGAEE-EPPQVLEIKPPPSAVTQRNKQPWHPDEDD--EEFTANEEEAEDEEDTI 417
Query: 944 --KKQSKKGTEEKKKPSDFKKK-VIKME---QQYESS---SDGTEKLPEREEI------C 988
++Q + + + S+ ++ + ME QQY + G+ + + +E+ C
Sbjct: 418 AAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDC 477
Query: 989 HFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAE---KSTGKGDSCDSSEDKKSK 1045
++ + D +S + D++ ++DE S+ E S + + SED +S+
Sbjct: 478 EPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQ 537
Query: 1046 NGAYGREK 1053
+ A E+
Sbjct: 538 SQADEEEE 545
Score = 36.6 bits (83), Expect = 0.31
Identities = 51/220 (23%), Positives = 91/220 (41%), Gaps = 28/220 (12%)
Query: 1262 KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK 1321
K++T ++ + P +E + + V S + + EE+ + H +L L ++ E T+
Sbjct: 2202 KQQTIRELFDMPLEEPSSSSVPSAPEEE-EETVASKQTH-ILEQALCRAEDEEDIRAATQ 2259
Query: 1322 PKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSE--SEDEQRPRTRSAKKAELEENQR 1379
K + + +E +E+ F +G EE +EDE+ R A +E+
Sbjct: 2260 AKAEQVAE-------LAEFNENDGFP-AGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTP 2311
Query: 1380 SYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE-----EEEEEEDENDDSKS 1434
+ K ++E S E K E+ E +++ ++ +EE +EEEE D S
Sbjct: 2312 IERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEEEEGPGAGDESS 2371
Query: 1435 PGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERER 1474
G G R+ K K E R++ER R
Sbjct: 2372 CGTGGGTHRRSKK-----------AKAPERPGTRVSERLR 2400
Score = 35.8 bits (81), Expect = 0.53
Identities = 28/107 (26%), Positives = 54/107 (50%), Gaps = 4/107 (3%)
Query: 1878 DETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGN 1937
D +S S S +D ++ ++ ++++S S + +++ E + S+S+ E D+ G
Sbjct: 492 DSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGV 551
Query: 1938 NPSVSLKLEESKATSSSNPSSPAPDWY--KDFVTD--ADAEVLEHSG 1980
++ E+S+A + S P +P P K +TD A AE L+ G
Sbjct: 552 EYLLARDEEQSEADAGSGPPTPGPTTLGPKKEITDIAAAAESLQPKG 598
>gi|58331268 excision repair protein ERCC6-like [Homo sapiens]
Length = 1250
Score = 129 bits (323), Expect = 5e-29
Identities = 103/316 (32%), Positives = 158/316 (50%), Gaps = 43/316 (13%)
Query: 1950 ATSSSNPSSPAPDW-YKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLIS 2008
+ N +PD + D VTD ++E SGKM+ L ++L+ + G + LVFSQS
Sbjct: 431 SAQDGNEGEDSPDVDHIDQVTDDT--LMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQI 488
Query: 2009 LDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTT-AQSRKKWAEEFNDE 2067
L++IE L+ R+ R+DG+ T R+K F +
Sbjct: 489 LNIIERLLKN----------------------RHFKTLRIDGTVTHLLEREKRINLF--Q 524
Query: 2068 TNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRF 2127
N +F+++T+ G +G+ L AA RV+IFD SWNP+ D Q++ RVYR GQ + V VYR
Sbjct: 525 QNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRL 584
Query: 2128 LAQGTMEDKIYDRQVTKQSLSFRVV-DQQQVERHFTMNELTELYTFEPDLLDDPNSEKKK 2186
+ GT+E+KIY RQV K SL + +++ R+F+ EL EL+T E DL + + +
Sbjct: 585 ITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYFSKQELRELFTIE-DLQNSVTQLQLQ 643
Query: 2187 KRDTPMLPKDTILAE-LLQIHKEHIVGYHEHDSL----LDHKEEEELTEEE-------RK 2234
D L E + + I G +HD + L KEE ++ EE +K
Sbjct: 644 SLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYTCDLSVKEELDVVEESHYIQQRVQK 703
Query: 2235 AAW-AEYEAEKKGLTM 2249
A + E+E++ K M
Sbjct: 704 AQFLVEFESQNKEFLM 719
Score = 103 bits (257), Expect = 2e-21
Identities = 117/466 (25%), Positives = 203/466 (43%), Gaps = 88/466 (18%)
Query: 1457 NALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHR 1516
N K+ K ++ ++ +E L E+ E D DE + + ++R
Sbjct: 45 NLAKDIFPNEKVLSRIQKIQEALEELAEQGD--------------DEFTDVCNSGLLLYR 90
Query: 1517 NMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLC 1576
+ +L HQ +G+ F++ + K G ILA MGLGKT+Q+++FL +
Sbjct: 91 ELHNQLFEHQKEGIAFLYSLYRDGRK--------GGILADDMGLGKTVQIIAFLSGMF-- 140
Query: 1577 DKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQ--ERSYMLQRW 1634
D + L++ P N W+ EF KW G++ + T P ER+ L R
Sbjct: 141 DASLVNHVLLIMPTNLINTWVKEFIKWTPGMR---------VKTFHGPSKDERTRNLNRI 191
Query: 1635 QEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVS 1694
Q+ GV+I Y+M N Q +L + V D+V+ DE H +K ++ +
Sbjct: 192 QQRNGVIITTYQMLINNWQ-------QLSSFRGQEFVW---DYVILDEAHKIKTSSTKSA 241
Query: 1695 KAMNSIRSRRRIILTGTPLQNNLIEYHCMVNF-IKENLLGSIKEFRNRFINPIQNGQCAD 1753
+I + R++LTGTP+QNNL E + +F + +LLG++K F+ + NPI + D
Sbjct: 242 ICARAIPASNRLLLTGTPIQNNLQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKD 301
Query: 1754 STMVDVRVMKKRAHILYEMLAGC--------VQRK--------------DYTALTKF--L 1789
+T + + K + L ++ VQ+K D A+ + L
Sbjct: 302 ATPGEKALGFKISENLMAIIKPYFLRRTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSL 361
Query: 1790 PPKHEYVLAVRMTSIQCKLYQYY--LDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH 1847
K++ ++ +R+ +Q ++Y+ + LDH+ + + + G +L ++ H
Sbjct: 362 SRKNDLIIWIRLVPLQEEIYRKFVSLDHIKELLMETRSPLAELG--------VLKKLCDH 413
Query: 1848 PWCLQLDYISKENKGYFD-------EDSMD-EFIASDSDETSMSLS 1885
P L N G F EDS D + I +D+T M S
Sbjct: 414 PRLLSARACCLLNLGTFSAQDGNEGEDSPDVDHIDQVTDDTLMEES 459
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 127 bits (320), Expect = 1e-28
Identities = 249/1233 (20%), Positives = 475/1233 (38%), Gaps = 186/1233 (15%)
Query: 354 LKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCA 413
L K+ + + + + +++ + E +++ +K + K + K K + E+P
Sbjct: 202 LALLKAQIDPVLLKNSSQQDNSSRESPSLEDEETKKEEETPKQEEQKESEKMKSEEQPMD 261
Query: 414 LEKKDISKS-EAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTS 472
LE + + E +K+ + E +P + E KK ++E ++
Sbjct: 262 LENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFK--ENV 319
Query: 473 EDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDN 532
+ + +++ + P+D ++E + + G + + E S+ + D
Sbjct: 320 KPIKVEVKECRAD-PKDTKSSMEKPVAQEPERIEFGGNIKSSHEITEKSTEETEKLKNDQ 378
Query: 533 RGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKC--- 589
+ I K+ +KL+ +SP+KG C+ V K+ K + + E C
Sbjct: 379 QAKIP-------LKKREIKLSDDF--DSPVKGPLCKSVTPTKEFLKD-EIKQEEETCKRI 428
Query: 590 ----GLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNE 645
LG E + LV EVS D R +P KT P+ S S +
Sbjct: 429 STITALGHEG---KQLVNGEVS------DERVAPNFKTEPIETKFYETKEESYSPSKDRN 479
Query: 646 TVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSR 705
+ E + S +S I + K +L K ET D+D +++L+ S+
Sbjct: 480 IITEG----------NGTESLNSVITSMKTGELEK----ETAPLRKDADSSISVLEIHSQ 525
Query: 706 MSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKR-KRKSSTSGSDFDTKKGKSAKSSI 764
+ D +++T + K K++ S ++ T KG+ KS
Sbjct: 526 KAQIEEPDPP------------EMETSLDSSEMAKDLSSKTALSSTESCTMKGEE-KSPK 572
Query: 765 ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKH-SKKGMD 823
K KR E +LEK K+ A R + IP + E EK S + +
Sbjct: 573 TKKDKRPPILECLE---KLEKSKKTFLDKDAQRLSP--IPEEVPKSTLESEKPGSPEAAE 627
Query: 824 NQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRD-----RLPKKQQASA 878
N+ E + + E + + T S+ G K + L++ ++ +A
Sbjct: 628 TSPPSNIIDHCEKLASEKEVVECQST-STVGGQSVKKVDLETLKEDSEFTKVEMDNLDNA 686
Query: 879 STDGVDKLSGKEQSF--TSLEVRKVAETKEKSKHLKTKTCKKVQDGLS---DIAEKFLKK 933
T G+++ S + S + + + V E + + T ++ ++G+ I+ + K
Sbjct: 687 QTSGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKP 746
Query: 934 DQSDETSEDDKKQSKKGTEEKK-----------KPSDFKKKVIKMEQQYESSSDGTEKLP 982
D + E + KQ K EE+K + S KV ++ Q G +
Sbjct: 747 DSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPRISRPTAKVAEIRDQKADKKRGEGEDE 806
Query: 983 EREEICHFPKGIKQ--IKNGTTDGEKKSKKIRDK-----TSKKKDELSDYAEKSTGKGDS 1035
EE K K+ +K D K K++ K T + Y+ +G
Sbjct: 807 VEEESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKVRWTGSRTRGRWKYSSNDESEGSG 866
Query: 1036 CDSS-------EDKKSKNGAYGREKKRCKLLGKSSRKRQD--CSSSDTEKYS-------- 1078
+ S E+K+S+ + + CK G + C S D+ ++
Sbjct: 867 SEKSSAASEEEEEKESEEAILADDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLM 926
Query: 1079 MKEDG------------CNSSDKRLKRIELR-ERRNLSSKRNTKEIQSGSSSSDA----- 1120
+ DG C +++L+ +++ +++ + +R + + G S +
Sbjct: 927 IIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENIIPPQE 986
Query: 1121 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGE 1180
+ SED ++KK+ SKK + E++ R + + + IEDD + + G
Sbjct: 987 PDFSEDQEEKKK--DSKKSKANLLERRSTRTRKCISYRFDEFDEAIDEAIEDDIKEADGG 1044
Query: 1181 GSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLE 1240
G + I +T H G K + +D++ +N R A +
Sbjct: 1045 GVGRGKDISTIT------GHRG-----------KDISTILDEERKENKRPQRAAAARRKK 1087
Query: 1241 EIKAN-LSSDEDGSSDDEPEEGKKRTGKQNE-----ENPGDEEAKNQVNSESDSDSEESK 1294
+ N L SD + ++ +E K G Q+E ENP + E N +SD+D +
Sbjct: 1088 RRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEEDPPSNDDSDTDFCSRR 1147
Query: 1295 KPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSED---SDFQESGV 1351
R+ R +R + +KT K++ + + +S DSE DF + V
Sbjct: 1148 LRRHPSRPMRQSRRL-------RRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFV 1200
Query: 1352 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENK-----SNSEE 1406
S Q+ + + +E + +Q+S ++ K+ RR+ + SSSE++ NSE+
Sbjct: 1201 ETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSED 1260
Query: 1407 EEEEKEEE----------EEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQ 1456
+E KE + +E E +EEEEE+E S RK++ +I D++ +
Sbjct: 1261 DELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPS------RKRLHRIETDEEESCDNA 1314
Query: 1457 --NALKEEEERRKRIAEREREREKLREVIEIED 1487
+A + + + R+ E+E K IE ++
Sbjct: 1315 HGDANQPARDSQPRVLPSEQESTKKPYRIESDE 1347
Score = 81.3 bits (199), Expect = 1e-14
Identities = 245/1259 (19%), Positives = 451/1259 (35%), Gaps = 208/1259 (16%)
Query: 245 VFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYS 304
V LE+ L +N++K K+ E+S+ E+ K C + K S
Sbjct: 291 VIVKLEKPLPENEEK-KIIKEESDSFKENVKPI--KVEVKECRADPKDTKSSM------- 340
Query: 305 YSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADI 364
++ + + + IE N+ SS+ + +++T+ +E +LK + +
Sbjct: 341 -------EKPVAQEPERIEFGGNIKSSH-EITEKSTEETE--------KLKNDQQAKIPL 384
Query: 365 KKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEA 424
KK + L +D +S + TKE + K E + K +
Sbjct: 385 KKREIKLSDDFDSPVKG-PLCKSVTPTKEFLKDEIKQEEETCKRISTITA----LGHEGK 439
Query: 425 KLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPS 484
+L +V E + N TE T E S K+ N +E L+ I S+ +
Sbjct: 440 QLVNGEVSDERVAPNFKTEPIETKFYETKEESYSPSKDRNIITEGNGTESLNSVITSMKT 499
Query: 485 SVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKV 544
E E + SS+ +E S K I D S ++++
Sbjct: 500 GELEK--ETAPLRKDADSSIS-----------VLEIHSQKAQIEEPDPPEMETSLDSSEM 546
Query: 545 TKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLN--PKLEKCGLGQENSDNEHL- 601
K+L K S + +KG + + P+ K + L KLEK + D + L
Sbjct: 547 AKDLSSKTALSSTESCTMKGEE--KSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLS 604
Query: 602 -VENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVP---- 656
+ EV ES+ SP ET+P SN + C + EK+ +
Sbjct: 605 PIPEEVPKSTLESEKPGSPEA--------AETSP-PSNIIDHCEKLASEKEVVECQSTST 655
Query: 657 -----VRKKD----KRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS 707
V+K D K +S + ++ + S E + + K V
Sbjct: 656 VGGQSVKKVDLETLKEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEE 715
Query: 708 HSSSSDTDINEIHTNH--KTLYDLKTQAGKDDKGKR-----KRKSSTSGSDFDTKKGKSA 760
++S +T+I K + ++ K D + ++ T + T G++
Sbjct: 716 TTASENTEITSERQKEGIKLTIRISSRKKKPDSPPKVLEPENKQEKTEKEEEKTNVGRTL 775
Query: 761 KSS---------IISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS 811
+ S + + ++ + + E+E+E ++ K KK + KD +S
Sbjct: 776 RRSPRISRPTAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDKKEILKK---SEKDTNS 832
Query: 812 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDR-- 869
+ K + G + + S+D++E ++ +++E +K++ L D
Sbjct: 833 KVSKVKPKGKVRWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEKESEEAILADDDE 892
Query: 870 ------LPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKT-CKKVQDG 922
LP + D D SG + + + + + + K C+K+++
Sbjct: 893 PCKKCGLPNHPELILLCDSCD--SGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQ 950
Query: 923 LSDIAEKFLKKDQSDETSE--------------DDKKQSKKGTEEKKKPSDFKKKVIKME 968
L D+ KK++++ E + + EEKKK S K +
Sbjct: 951 LQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPDFSEDQEEKKKDSKKSKANLLER 1010
Query: 969 QQYESSSDGTEKLPEREEICHFPKGIKQ-IKNGTTDGEKKSKKIRDKTSKKKDELSDYAE 1027
+ + + + E +E + I+ IK G + K I T + ++S +
Sbjct: 1011 RSTRTRKCISYRFDEFDEA--IDEAIEDDIKEADGGGVGRGKDISTITGHRGKDISTILD 1068
Query: 1028 KSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTE---------KYS 1078
+ + E+K+ + A R KKR +L S D S+ E ++
Sbjct: 1069 E--------ERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFV 1120
Query: 1079 MKEDGCNSSD---------------KRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEES 1123
+ ++ + S+ +RL+R R R S + K + S D EE
Sbjct: 1121 VSDENPDESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQ-SRRLRRKTPKKKYSDDDEEEE 1179
Query: 1124 SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSS 1183
SE+N + + S + E +R R + KR Q + S SD Q S+ G
Sbjct: 1180 SEENSRDSESDFSDDFSDDFVETRRRRSRRNQKR-QINYKEDSESD---GSQKSLRRG-- 1233
Query: 1184 DEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1243
++I+ V + + SS S + LSK N ++ +AK+ K
Sbjct: 1234 --KEIRRVHKRRLSSSE------SEESYLSK------------NSEDDELAKESKRSVRK 1273
Query: 1244 ANLSSDEDGSSDDEPEE--GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHR 1301
S+DE +D+E EE GK + + +EE+ + + +++ + +S
Sbjct: 1274 RGRSTDEYSEADEEEEEEEGKPSRKRLHRIETDEEESCDNAHGDANQPARDS-------- 1325
Query: 1302 LLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDE 1361
+ + P E + K R E E+ DF+ G +
Sbjct: 1326 ---------------QPRVLPSEQESTKKPYR----IESDEEEDFENVGKVGSPLDYSLV 1366
Query: 1362 QRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1420
P T + EN K +K + K +S+ SN +E EEEE+E
Sbjct: 1367 DLPSTNGQSPGKAIENLIG-KPTEKSQTPKDNSTASASLASNGTSGGQEAGAPEEEEDE 1424
Score = 46.2 bits (108), Expect = 4e-04
Identities = 31/117 (26%), Positives = 60/117 (51%), Gaps = 18/117 (15%)
Query: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLR 1452
Q+D+SS + E+EE +KEEE ++EE++E E+ ++++ + R
Sbjct: 219 QQDNSSRESPSLEDEETKKEEETPKQEEQKESEKMKSEEQPMDLENR------------- 265
Query: 1453 TETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKE 1509
T N L+E ++++ E E+E KL ++++E P K++ +E + KE
Sbjct: 266 -STANVLEETTVKKEK--EDEKELVKLPVIVKLEKPLPEN--EEKKIIKEESDSFKE 317
>gi|58219008 RAD26L hypothetical protein [Homo sapiens]
Length = 712
Score = 122 bits (307), Expect = 3e-27
Identities = 78/204 (38%), Positives = 116/204 (56%), Gaps = 30/204 (14%)
Query: 1964 YKDFVT---DADAEVL---EHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLE 2017
+ DFV DA E L ++SGKM +L ++L + DKVL+FS S LD+++ +
Sbjct: 497 FPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNRDKVLLFSFSTKLLDVLQQYC- 555
Query: 2018 LASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFII 2077
+AS +DY RLDGST ++ R K +EFN +V + ++
Sbjct: 556 MAS---------------------GLDYRRLDGSTKSEERLKIVKEFNSTQDVN--ICLV 592
Query: 2078 STKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKI 2137
ST AG LG+N V AN V++FD +WNP+ D+Q+I R YR GQ + V V R ++ GT+E+ +
Sbjct: 593 STMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIM 652
Query: 2138 YDRQVTKQSLSFRVVDQQQVERHF 2161
Y RQ+ KQ L VV + +R+F
Sbjct: 653 YLRQIYKQQLHCVVVGSENAKRYF 676
Score = 100 bits (249), Expect = 2e-20
Identities = 105/423 (24%), Positives = 175/423 (41%), Gaps = 84/423 (19%)
Query: 1522 LKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVL------- 1574
L+ +Q +G +F++ G GCIL MGLGKT+QV+SFL VL
Sbjct: 134 LRDYQREGTRFLYGHYIH---------GGGCILGDDMGLGKTVQVISFLAAVLHKKGTRE 184
Query: 1575 -------------LCDKLDFSTA----LVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSE 1617
+ + STA L+V PL+ NW +E + W V+
Sbjct: 185 DIENNMPEFLLRSMKKEPLSSTAKKMFLIVAPLSVLYNWKDELDTWGY-------FRVTV 237
Query: 1618 LATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDF 1677
L ++ E + QR E + + YE R N
Sbjct: 238 LHGNRKDNELIRVKQRKCE---IALTTYETLRLCLDELNSLEWSA--------------- 279
Query: 1678 VVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKE 1737
V+ DE H +KN + V++ M +++ RI LTGT LQNN+ E C++++ LLGS
Sbjct: 280 VIVDEAHRIKNPKARVTEVMKALKCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSGTY 339
Query: 1738 FRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVL 1797
F+ +F +P+++GQ +T ++ +K L + ++G R+ T + LP K + ++
Sbjct: 340 FKKQFSDPVEHGQRHTATKRELATGRKAMQRLAKKMSGWFLRRTKTLIKDQLPKKEDRMV 399
Query: 1798 AVRMTSIQCKLYQYYL--DHLTGVGNNSEGGRGKAGAK-----------------LFQDF 1838
+T Q +YQ L + +T + +SE ++G K L+ +
Sbjct: 400 YCSLTDFQKAVYQTVLETEDVTLILQSSEPCTCRSGQKRRNCCYKTNSHGETVKTLYLSY 459
Query: 1839 -QMLSRIWTHPWCLQLDYISKENKGYFDE------DSMDEFIASDSDETSMSLSSDDYTK 1891
+L ++ H LQ SK+ + +F+ D +LS Y+
Sbjct: 460 LTVLQKVANHVALLQAASTSKQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSG 519
Query: 1892 KKK 1894
K K
Sbjct: 520 KMK 522
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 120 bits (301), Expect = 2e-26
Identities = 163/681 (23%), Positives = 280/681 (41%), Gaps = 106/681 (15%)
Query: 843 RKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVA 902
+KQ+ ++ S + +D D E+ K+Q + G K K+Q F ++ K
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK-- 60
Query: 903 ETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKG---------TEE 953
E +E S + ++ +A K + ++ + TS+D KK+ +KG +EE
Sbjct: 61 ELEELSLE-----AQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115
Query: 954 KKKPSDFKKKVIKMEQQYESSSDGTE---KLPEREEICHFPKGIKQIKNGTTDG----EK 1006
+ KK K + + S SD + KLP++ KG Q N DG E
Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKA------KGKAQKSNKKWDGSEEDED 169
Query: 1007 KSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSED-KKSKNGAYGREKKRCKLLGKSSRK 1065
SKKI++++ + G+S D S++ +S+ G +KK K K
Sbjct: 170 NSKKIKERS------------RINSSGESGDESDEFLQSRKG----QKKNQK--NKPGPN 211
Query: 1066 RQDCSSSDTEKYSMKEDGCNSSDKRLKRIELR--ERRNLSSKRNTKEIQSGSSSSDAEES 1123
+ + D + +K ++K+ + + R E+ L + +E+++G D +
Sbjct: 212 IESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKK--DQSKQ 269
Query: 1124 SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSS 1183
E +K ++ T K V ++ ++A+ +++ D E D + +
Sbjct: 270 KESQRKFEEETVKSKVTV-------DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKK 322
Query: 1184 DEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1243
E++ K + S T + EAL+K + +++ + E RI + LEE++
Sbjct: 323 GEKEEKEKEKKKGPSKAT---VKAMQEALAK---LKEEEERQKREEEERIKR---LEELE 373
Query: 1244 ANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1303
A +E E+ K+ KQ E+ E K ++ E ++ ++ R R
Sbjct: 374 AKRKEEE------RLEQEKRERKKQKEK-----ERKERLKKEGKLLTKSQREARARAEAT 422
Query: 1304 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSS--EDSEDSDFQESGVSEEVSESEDE 1361
KL + G K + PK+ + + R+K+ E E S+ E + EV E
Sbjct: 423 L-KLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVP 481
Query: 1362 QRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN-------KSNSEEEEEEKEEE 1414
++ T + E EE+ +E E K N EEEEEE+EEE
Sbjct: 482 EKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEE 541
Query: 1415 EEEEEEEEEEEE---------DEND----DSKSPGKG-RKKIRKILKDDKLRTETQNALK 1460
EE+EE EEEEEE DE D D K GK KK K + D + K
Sbjct: 542 EEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK 601
Query: 1461 EE---EERRKRIAEREREREK 1478
EE ++ ++RI +R E K
Sbjct: 602 EERAYDKAKRRIEKRRLEHSK 622
Score = 111 bits (278), Expect = 8e-24
Identities = 161/751 (21%), Positives = 295/751 (39%), Gaps = 155/751 (20%)
Query: 659 KKDKRNSSDSAIDN------------------PKPNKLPKSKQSETVDQNSDSDEMLAIL 700
KK K S DS D+ +P K K+ E Q+ D D++L L
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 701 KEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSA 760
+E+S + +D + + + T K KG++ +K S +D + + K +
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEF-TSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121
Query: 761 KSSIISKKKRQTQSESSNYD--SELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHS 818
KS +K K + S S + D ++L K+ K G A+ + K+ +D SE+++
Sbjct: 122 KSKKTAKPKVEMYSGSDDDDDFNKLPKKAK-----GKAQKSNKK------WDGSEEDE-- 168
Query: 819 KKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASA 878
D++++ +ER +S+ + D+ ++ R K Q+
Sbjct: 169 --------------------DNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQK--- 205
Query: 879 STDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDE 938
+ G + SG E S +++ VA+ K + K + K D + L+K + E
Sbjct: 206 NKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKK--------RDEEKAKLRKLKEKE 257
Query: 939 TSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIK 998
E KK K E ++K F+++ +K + + T +P EE P +
Sbjct: 258 ELETGKKDQSKQKESQRK---FEEETVKSKVTVD-----TGVIPASEEKAETPTAAEDDN 309
Query: 999 NGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKL 1058
G + K KK +K K+K++ K+T K ++ K+ + E++R K
Sbjct: 310 EGDKKKKDKKKKKGEKEEKEKEKKKG-PSKATVKAMQEALAKLKEEEERQKREEEERIKR 368
Query: 1059 LGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSS 1118
L + KR++ + EK K+ K E +ER K TK + + +
Sbjct: 369 LEELEAKRKEEERLEQEKRERKKQ---------KEKERKERLKKEGKLLTKSQREARARA 419
Query: 1119 DA--EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQN 1176
+A + + + S KK I ++KKR + + K+ + + +E +Q
Sbjct: 420 EATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQ- 478
Query: 1177 SIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKK 1236
G ++++ P PV ++++D D
Sbjct: 479 ----GVPEKEETPP--------------------------PVEPEEEEDTED-------- 500
Query: 1237 MLLEEIKANLSSDEDGSSDDEPE--EGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK 1294
A L E +SD+E E EG K + +ENP +EE + + E D +SEE +
Sbjct: 501 -------AGLDDWEAMASDEETEKVEGNK-VHIEVKENP-EEEEEEEEEEEEDEESEEEE 551
Query: 1295 KPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEE 1354
+ S+G G+E+ K + K+ +K S E S DS++
Sbjct: 552 EEEGE----------SEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEY-------- 593
Query: 1355 VSESEDEQRPRTRSAKKAELEENQRSYKQKK 1385
+S+D++ R+ KA+ +R + K
Sbjct: 594 --DSDDDRTKEERAYDKAKRRIEKRRLEHSK 622
Score = 87.0 bits (214), Expect = 2e-16
Identities = 133/687 (19%), Positives = 267/687 (38%), Gaps = 87/687 (12%)
Query: 416 KKDISKSEAKLSRKQVDSEHMHQNVP----TEEQRTNKSTGGEHKKSDRKEEPQYEPANT 471
KK +KSE ++ +D + + + +EQ KS G + K+ +++ + +
Sbjct: 3 KKQKNKSEDS-TKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61
Query: 472 SEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKD 531
E+L ++ + + + E E +S D + G G +Q + + + + KD
Sbjct: 62 LEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSE-ELEDKD 120
Query: 532 NRGGIKSKTTAKVTKELYV---------KLTPVSLSNSPIKGADCQEVPQDKDGYKSCGL 582
+ KSK TAK E+Y KL + + +D+D K
Sbjct: 121 S----KSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKE 176
Query: 583 NPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEE 642
++ G + SD L +++ + K P N + N D++
Sbjct: 177 RSRINSSGESGDESD---------EFLQSRKGQKKNQKNKPGP-------NIESGNEDDD 220
Query: 643 CNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKE 702
+ +K + ++++++ + + K KL + ++ ET ++ + E
Sbjct: 221 ASFKIKTVAQKKAEKKERERKKRDE---EKAKLRKLKEKEELETGKKDQSKQKESQRKFE 277
Query: 703 VSRMSHSSSSDTDI---NEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKS 759
+ + DT + +E T + + K K K+K+K + + KKG S
Sbjct: 278 EETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS 337
Query: 760 -AKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHS 818
A + + + + E E E+ IK + ++ A R ++R+ K + EK
Sbjct: 338 KATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKER 397
Query: 819 KKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGT---VDKDTTIMELRDRLPKKQ- 874
K+ + +G L T K +RE + AE T + + +D LPKK+
Sbjct: 398 KERLKKEG--KLLT-----------KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRP 444
Query: 875 --QASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLK 932
+ +L KE S S+E+ E E+ K +T V+ + E
Sbjct: 445 IYEDKKRKKIPQQLESKEVS-ESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGL 503
Query: 933 KDQSDETSEDDKKQ---SKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 989
D S+++ ++ +K E K+ P + E++ E + E+ E EE
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEE--------EEEEEEEEEEDEESEEEEE--- 552
Query: 990 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAY 1049
++ ++ ++G+++ +K+ D+ K L K DS +D+ + AY
Sbjct: 553 -----EEGESEGSEGDEEDEKVSDEKDSGK-TLDKKPSKEMSSDSEYDSDDDRTKEERAY 606
Query: 1050 GREKKRCKLLGKSSRKRQDCSSSDTEK 1076
+ K+R + R+ + + +TEK
Sbjct: 607 DKAKRRIE-----KRRLEHSKNVNTEK 628
Score = 86.3 bits (212), Expect = 3e-16
Identities = 94/469 (20%), Positives = 194/469 (41%), Gaps = 42/469 (8%)
Query: 1065 KRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESS 1124
K+Q S D+ K + D + + + +E + K+ ++ + D +
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKEL 62
Query: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184
E+ + Q + ++ V VK + N ++K K+ +D+D + + S
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSK 122
Query: 1185 EQKI-KPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1243
+K KP E S +A K+ D + D +N K + E +
Sbjct: 123 SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN---SKKIKERSR 179
Query: 1244 ANLSSDEDGSSDDEPEEGKKRTGKQNEENPG--------DEEAKNQVNSESDSDSEESKK 1295
N SS E G DE + +K K + PG D++A ++ + + +E KK
Sbjct: 180 IN-SSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAE--KK 236
Query: 1296 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV---S 1352
R R + K + + EE +T K+ + K ++RK E + ++GV S
Sbjct: 237 ERERKKRDEEKAKLRKLKEKEELETGKKDQSKQK-ESQRKFEEETVKSKVTVDTGVIPAS 295
Query: 1353 EEVSES--------EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1404
EE +E+ E +++ + + KK E EE ++ K+ + +K +++ ++ K
Sbjct: 296 EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK--- 352
Query: 1405 EEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEE 1464
EEEE ++ EEEE ++ ++ K +++ + ++ K + E + + ++E
Sbjct: 353 --------EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404
Query: 1465 RRKRIAEREREREKLREVIEIEDAS----PTKCPITTKLVLDEDEETKE 1509
+ + R + +++ A P+K + K + ED++ K+
Sbjct: 405 GKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 453
Score = 60.5 bits (145), Expect = 2e-08
Identities = 125/645 (19%), Positives = 238/645 (36%), Gaps = 113/645 (17%)
Query: 243 NSVFENLEQLLQQNKKKIKVDSEK------SNKVYEHTSRFSPKKTSSNCNGEEKKLDDS 296
+ + + LE+L + + IK D E N E TS+ KK G+++ DD+
Sbjct: 56 DDILKELEELSLE-AQGIKADRETVAVKPTENNEEEFTSKDKKKKGQK---GKKQSFDDN 111
Query: 297 CSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKA 356
S + ++ K+KK + M S + D+ + + K + KA
Sbjct: 112 DSEEL----------EDKDSKSKKTAKPKVEMYSG-------SDDDDDFNKLPKKAKGKA 154
Query: 357 FKSVLADIKKAHLALEEDLNSEFRAMDAVNK--EKNTKEHKVIDAKFETKARKGEKPC-- 412
KS + K +ED + + + +N E + + + ++ K + KP
Sbjct: 155 QKS---NKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPN 211
Query: 413 ---------------ALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKK 457
+ +K K E + ++ + + + EE T K + K+
Sbjct: 212 IESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKE 271
Query: 458 SDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQE 517
S RK +E + +D +P+S E E ++ + +G + +
Sbjct: 272 SQRK----FEEETVKSKVTVDTGVIPAS---------EEKAETPTAAEDDNEGDKKKKDK 318
Query: 518 VESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGY 577
+ K + +G SK T K +E KL K + ++ ++++
Sbjct: 319 KKKKGEKEEKEKEKKKG--PSKATVKAMQEALAKL----------KEEEERQKREEEERI 366
Query: 578 KSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTS 637
K +LE+ + E +E E ++ + R R+K E +T
Sbjct: 367 K------RLEEL---EAKRKEEERLEQEKRERKKQKEKERKERLKK-------EGKLLTK 410
Query: 638 NSDE---ECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSD 694
+ E T+K Q V V KD ++ K K+P+ +S+ V S+S
Sbjct: 411 SQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEV---SESM 467
Query: 695 EMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDT 754
E+ A ++ + + E T AG DD SD +T
Sbjct: 468 ELCAAVEVMEQGVPEKEETPPPVEPEEEEDT-----EDAGLDDW-------EAMASDEET 515
Query: 755 KKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSED 814
+K + K I K+ + + E + E E+ + + G + ++ ++ + D
Sbjct: 516 EKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSE----GDEEDEKVSD 571
Query: 815 EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDK 859
EK S K +D + K + + E SDD K+ER + A+ ++K
Sbjct: 572 EKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEER-AYDKAKRRIEK 615
Score = 33.9 bits (76), Expect = 2.0
Identities = 29/112 (25%), Positives = 43/112 (38%), Gaps = 13/112 (11%)
Query: 1858 KENKGYFDEDSMDEFIASDSDET----------SMSLSSDDYTKKKKKGKKGKKDSSSSG 1907
K K FD++ +E DS S S DD+ K KK K + S+
Sbjct: 102 KGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKW 161
Query: 1908 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSP 1959
GS+ D + K RSR G E+G+ L+ + + + N P
Sbjct: 162 DGSEEDEDNSKKIKERSRINSSG---ESGDESDEFLQSRKGQKKNQKNKPGP 210
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 120 bits (300), Expect = 2e-26
Identities = 90/278 (32%), Positives = 141/278 (50%), Gaps = 30/278 (10%)
Query: 1975 VLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYK 2034
+++ SGK++LL ++LR +E G +VL+FSQ LDL+EDFL+ Y+
Sbjct: 1055 LIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLD---------------YE 1099
Query: 2035 GEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRV 2094
G Y R+DG T R++ + FN + F++ST+AG LGINL A+ V
Sbjct: 1100 G-------YKYERIDGGITGALRQEAIDRFN-APGAQQFCFLLSTRAGGLGINLATADTV 1151
Query: 2095 IIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQ 2154
IIFD+ WNP DIQ+ R +R GQ V +YRF+ + ++E++I K L+ VV
Sbjct: 1152 IIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRP 1211
Query: 2155 QQVERHFTMN--ELTELYTF-EPDLLDDPNSEKKKKRDTPMLPKDT-ILAELL---QIHK 2207
+ +M+ EL ++ F +L D N + K+ D+ ++ D +A LL Q
Sbjct: 1212 GLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDAT 1271
Query: 2208 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKK 2245
E + ++ L K + + EE K E E K+
Sbjct: 1272 EDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQ 1309
Score = 92.8 bits (229), Expect = 4e-18
Identities = 99/410 (24%), Positives = 170/410 (41%), Gaps = 52/410 (12%)
Query: 1456 QNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDED----EETKEPL 1511
Q+ +E+E E ++ + RE+I ED + + K L D T +P
Sbjct: 660 QSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPT 719
Query: 1512 VQVHRNMVI------KLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQ 1565
V+ L +Q++G+ ++ + + G+ ILA MGLGKT+Q
Sbjct: 720 VKYETQPRFITATGGTLHMYQLEGLNWL---------RFSWAQGTDTILADEMGLGKTIQ 770
Query: 1566 VVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQ 1625
+ FL++ L + LV PL+T +NW EF+ W + + R
Sbjct: 771 TIVFLYS-LYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIREN 829
Query: 1626 ERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGP------DFVV 1679
E S+ ED + G + + + VK L + +D +V
Sbjct: 830 EFSF------EDNAIK--GGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLV 881
Query: 1680 CDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFR 1739
DE H LKN S + +N + +++LTGTPLQNNL E ++NF+ +++ F
Sbjct: 882 VDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFL 941
Query: 1740 NRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAV 1799
F + + Q +KK L+++L + R+ + K +P K E ++ V
Sbjct: 942 EEFADISKEDQ-----------IKK----LHDLLGPHMLRRLKADVFKNMPAKTELIVRV 986
Query: 1800 RMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPW 1849
++ +Q K Y+Y L N+ GG + + D L + HP+
Sbjct: 987 ELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMD---LKKCCNHPY 1033
Score = 38.1 bits (87), Expect = 0.11
Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 8/113 (7%)
Query: 1323 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1382
+E +++ R + E++ D D+ E + + +++ K+ + N
Sbjct: 1294 REEDKIEEIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAA 1353
Query: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
Q+ +D+ SE SEEE+E+ +E E + + + +E D P
Sbjct: 1354 QE--------DQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPP 1398
Score = 37.7 bits (86), Expect = 0.14
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 7/57 (12%)
Query: 174 DSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYIC 230
+ D E CR C +GG L+CCD C +++ C+ L I N +W C C
Sbjct: 451 EEDDHMEYCRVCKDGGELLCCDACISSYHIHCL-----NPPLPDI--PNGEWLCPRC 500
Score = 36.6 bits (83), Expect = 0.31
Identities = 35/155 (22%), Positives = 72/155 (46%), Gaps = 17/155 (10%)
Query: 1310 SDGESGEEKKTKPKEHKEVKGR--NRRKVSSEDSEDSDFQES----GVSEEVSESEDEQR 1363
++GE+ EE + E R +R + ++ED++ + E V++ V ED+
Sbjct: 1241 NEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIE 1300
Query: 1364 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN--------KSNSEEEEEEKEEEE 1415
R K E E Y +K R + Q++ + N K + + +++++
Sbjct: 1301 EIEREIIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDN 1359
Query: 1416 EEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK 1450
+ E EEEDE+ D + +GR++ ++ L+++K
Sbjct: 1360 QSEYSVGSEEEDEDFDERP--EGRRQSKRQLRNEK 1392
Score = 35.4 bits (80), Expect = 0.70
Identities = 16/25 (64%), Positives = 21/25 (84%)
Query: 1405 EEEEEEKEEEEEEEEEEEEEEEDEN 1429
E +EEE+E EEE EEE E+EEED++
Sbjct: 431 EAKEEEEEYEEEGEEEGEKEEEDDH 455
Score = 34.7 bits (78), Expect = 1.2
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 6/92 (6%)
Query: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1375
+++K PK+ KE K RK DSE+ E E SES + K+
Sbjct: 48 KKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKR---R 104
Query: 1376 ENQRSYKQKKKRRRIKVQEDSSS---ENKSNS 1404
R K+KK +RR K + D E KS++
Sbjct: 105 RKHREKKEKKTKRRKKGEGDGGQKQVEQKSSA 136
Score = 34.7 bits (78), Expect = 1.2
Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 1384 KKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE--EEEEEEEEEEDENDDSKSPGKGRKK 1441
KK++R K Q+ ENK + ++++ EEE E +E E+ + G GRK+
Sbjct: 48 KKRKRGPKKQK----ENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKR 103
Query: 1442 IRKILKDDKLRTETQNALKEEEERRKRIAERE 1473
RK +K +T+ K E + ++ E++
Sbjct: 104 RRK--HREKKEKKTKRRKKGEGDGGQKQVEQK 133
Score = 34.3 bits (77), Expect = 1.6
Identities = 16/30 (53%), Positives = 22/30 (73%)
Query: 1401 KSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430
K + E +E+EEE EEE EEE E+E+E+D
Sbjct: 425 KEGVQWEAKEEEEEYEEEGEEEGEKEEEDD 454
Score = 34.3 bits (77), Expect = 1.6
Identities = 46/210 (21%), Positives = 85/210 (40%), Gaps = 18/210 (8%)
Query: 1182 SSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPV--------TVDDDDDDNDPENRI 1233
+S E++I V + ++ +H G +A S S T + D+N+ EN+
Sbjct: 1188 ASVEERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKE 1247
Query: 1234 AKKMLL----EEIKANLSSDEDGSSDDEPEEGKKRTGK-QNEENPGDEEAKNQVNSESDS 1288
++ E I L ++D + D + + + + + EE K +
Sbjct: 1248 EDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREII 1307
Query: 1289 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE 1348
EE+ P Y +LLRH + E+ + K V+ + ++++ +D+ +
Sbjct: 1308 KQEENVDPDYWEKLLRHHYE----QQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEY 1363
Query: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQ 1378
S SEE E DE RP R K +L +
Sbjct: 1364 SVGSEEEDEDFDE-RPEGRRQSKRQLRNEK 1392
Score = 33.5 bits (75), Expect = 2.6
Identities = 25/108 (23%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Query: 979 EKLPEREEICHFPK--GIKQIKNG------TTDGEKKSKKIRDKTSKKKDELSDYAEKST 1030
+++P++++I P G+K+ K G G+ + +K RD + E +Y EKS
Sbjct: 30 DRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSE 89
Query: 1031 GKGDSCDSSEDKKSKNGAYGREKKRCKLL----GKSSRKRQDCSSSDT 1074
G + +K + +++K+ K G +K+ + SS T
Sbjct: 90 SGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSAT 137
Score = 33.5 bits (75), Expect = 2.6
Identities = 15/24 (62%), Positives = 19/24 (79%)
Query: 1408 EEEKEEEEEEEEEEEEEEEDENDD 1431
E ++EEEE EEE EEE E++E DD
Sbjct: 431 EAKEEEEEYEEEGEEEGEKEEEDD 454
Score = 33.1 bits (74), Expect = 3.5
Identities = 37/191 (19%), Positives = 83/191 (43%), Gaps = 10/191 (5%)
Query: 1299 RHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE-SGVSEEVSE 1357
R +L H L V G + +E ++ ++ +++E + +E S V +E
Sbjct: 1200 RKMMLTH-LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNE 1258
Query: 1358 SEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV-QEDSSSENKSNSEEEEEEKEEEEE 1416
+ R + A + +N Y K + V +ED E + ++EE + +
Sbjct: 1259 AIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYW 1318
Query: 1417 EEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN-------ALKEEEERRKRI 1469
E+ E+ + D +++ GKG++ +++ +D + + N + +E+E+ +R
Sbjct: 1319 EKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERP 1378
Query: 1470 AEREREREKLR 1480
R + + +LR
Sbjct: 1379 EGRRQSKRQLR 1389
Score = 32.7 bits (73), Expect = 4.5
Identities = 16/54 (29%), Positives = 22/54 (40%), Gaps = 7/54 (12%)
Query: 180 EQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPE 233
+ C C +GG +I CD C A+ C+ L R +W C C E
Sbjct: 380 DYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRA-------PEGKWSCPHCEKE 426
Score = 32.7 bits (73), Expect = 4.5
Identities = 93/552 (16%), Positives = 205/552 (37%), Gaps = 87/552 (15%)
Query: 888 GKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS 947
G E+ F + E H + ++ D D E ++ ++ S K +
Sbjct: 1232 GTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSF--KVA 1289
Query: 948 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK 1007
+ E+ K + ++++IK E+ + D EKL H+ + + + G++
Sbjct: 1290 QYVVREEDKIEEIEREIIKQEENVDP--DYWEKLLRH----HYEQQQEDLARNLGKGKRV 1343
Query: 1008 SKKIR--DKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK----------- 1054
K++ D + +D S+Y+ S + + D + + ++ R +K
Sbjct: 1344 RKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPPLLARV 1403
Query: 1055 --RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSS-----KRN 1107
++LG ++R+R+ ++ ++ M ++ ++ + + + + R+
Sbjct: 1404 GGNIEVLGFNTRQRKAFLNA-VMRWGMPPQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRH 1462
Query: 1108 TKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSS 1167
E + S + A+ + ++Q + +VK+K + + + ++ S
Sbjct: 1463 LCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPS 1522
Query: 1168 SDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDN 1227
+D + + +S K P T ++S + S P T +
Sbjct: 1523 ADSKRSSR------ASSPTKTSPTTP-----------EASATNSPCTSKPATPAPSEKG- 1564
Query: 1228 DPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE----GKKRTGKQNEENP----GDEEAK 1279
E I+ L +E + +++PE+ G+K + + +P G+
Sbjct: 1565 ------------EGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEP 1612
Query: 1280 NQVNSESDSDS---EESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKV 1336
++ E + E +P YR + + GE GEEK +EH+E
Sbjct: 1613 RKIPLEDEVPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRE--------- 1663
Query: 1337 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDS 1396
+ E D G E+V + + E RP R ++ +R K +K R + +
Sbjct: 1664 -RPEGETGDL---GKREDV-KGDRELRPGPRDEPRS---NGRREEKTEKPRFMFNIADGG 1715
Query: 1397 SSENKSNSEEEE 1408
+E + + EE
Sbjct: 1716 FTELHTLWQNEE 1727
Score = 32.3 bits (72), Expect = 5.9
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 1395 DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKD 1448
D + E K + E+E + E +EEEEE EEE E + K + ++ KD
Sbjct: 411 DRAPEGKWSCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKD 464
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 120 bits (300), Expect = 2e-26
Identities = 90/278 (32%), Positives = 141/278 (50%), Gaps = 30/278 (10%)
Query: 1975 VLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYK 2034
+++ SGK++LL ++LR +E G +VL+FSQ LDL+EDFL+ Y+
Sbjct: 1055 LIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLD---------------YE 1099
Query: 2035 GEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRV 2094
G Y R+DG T R++ + FN + F++ST+AG LGINL A+ V
Sbjct: 1100 G-------YKYERIDGGITGALRQEAIDRFN-APGAQQFCFLLSTRAGGLGINLATADTV 1151
Query: 2095 IIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQ 2154
IIFD+ WNP DIQ+ R +R GQ V +YRF+ + ++E++I K L+ VV
Sbjct: 1152 IIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRP 1211
Query: 2155 QQVERHFTMN--ELTELYTF-EPDLLDDPNSEKKKKRDTPMLPKDT-ILAELL---QIHK 2207
+ +M+ EL ++ F +L D N + K+ D+ ++ D +A LL Q
Sbjct: 1212 GLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDAT 1271
Query: 2208 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKK 2245
E + ++ L K + + EE K E E K+
Sbjct: 1272 EDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQ 1309
Score = 92.8 bits (229), Expect = 4e-18
Identities = 99/410 (24%), Positives = 170/410 (41%), Gaps = 52/410 (12%)
Query: 1456 QNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDED----EETKEPL 1511
Q+ +E+E E ++ + RE+I ED + + K L D T +P
Sbjct: 660 QSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPT 719
Query: 1512 VQVHRNMVI------KLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQ 1565
V+ L +Q++G+ ++ + + G+ ILA MGLGKT+Q
Sbjct: 720 VKYETQPRFITATGGTLHMYQLEGLNWL---------RFSWAQGTDTILADEMGLGKTIQ 770
Query: 1566 VVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQ 1625
+ FL++ L + LV PL+T +NW EF+ W + + R
Sbjct: 771 TIVFLYS-LYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIREN 829
Query: 1626 ERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGP------DFVV 1679
E S+ ED + G + + + VK L + +D +V
Sbjct: 830 EFSF------EDNAIK--GGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLV 881
Query: 1680 CDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFR 1739
DE H LKN S + +N + +++LTGTPLQNNL E ++NF+ +++ F
Sbjct: 882 VDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFL 941
Query: 1740 NRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAV 1799
F + + Q +KK L+++L + R+ + K +P K E ++ V
Sbjct: 942 EEFADISKEDQ-----------IKK----LHDLLGPHMLRRLKADVFKNMPAKTELIVRV 986
Query: 1800 RMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPW 1849
++ +Q K Y+Y L N+ GG + + D L + HP+
Sbjct: 987 ELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMD---LKKCCNHPY 1033
Score = 38.1 bits (87), Expect = 0.11
Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 8/113 (7%)
Query: 1323 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1382
+E +++ R + E++ D D+ E + + +++ K+ + N
Sbjct: 1294 REEDKIEEIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAA 1353
Query: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
Q+ +D+ SE SEEE+E+ +E E + + + +E D P
Sbjct: 1354 QE--------DQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPP 1398
Score = 37.7 bits (86), Expect = 0.14
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 7/57 (12%)
Query: 174 DSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYIC 230
+ D E CR C +GG L+CCD C +++ C+ L I N +W C C
Sbjct: 451 EEDDHMEYCRVCKDGGELLCCDACISSYHIHCL-----NPPLPDI--PNGEWLCPRC 500
Score = 36.6 bits (83), Expect = 0.31
Identities = 35/155 (22%), Positives = 72/155 (46%), Gaps = 17/155 (10%)
Query: 1310 SDGESGEEKKTKPKEHKEVKGR--NRRKVSSEDSEDSDFQES----GVSEEVSESEDEQR 1363
++GE+ EE + E R +R + ++ED++ + E V++ V ED+
Sbjct: 1241 NEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIE 1300
Query: 1364 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN--------KSNSEEEEEEKEEEE 1415
R K E E Y +K R + Q++ + N K + + +++++
Sbjct: 1301 EIEREIIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDN 1359
Query: 1416 EEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK 1450
+ E EEEDE+ D + +GR++ ++ L+++K
Sbjct: 1360 QSEYSVGSEEEDEDFDERP--EGRRQSKRQLRNEK 1392
Score = 35.4 bits (80), Expect = 0.70
Identities = 16/25 (64%), Positives = 21/25 (84%)
Query: 1405 EEEEEEKEEEEEEEEEEEEEEEDEN 1429
E +EEE+E EEE EEE E+EEED++
Sbjct: 431 EAKEEEEEYEEEGEEEGEKEEEDDH 455
Score = 34.7 bits (78), Expect = 1.2
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 6/92 (6%)
Query: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1375
+++K PK+ KE K RK DSE+ E E SES + K+
Sbjct: 48 KKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKR---R 104
Query: 1376 ENQRSYKQKKKRRRIKVQEDSSS---ENKSNS 1404
R K+KK +RR K + D E KS++
Sbjct: 105 RKHREKKEKKTKRRKKGEGDGGQKQVEQKSSA 136
Score = 34.7 bits (78), Expect = 1.2
Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 1384 KKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE--EEEEEEEEEEDENDDSKSPGKGRKK 1441
KK++R K Q+ ENK + ++++ EEE E +E E+ + G GRK+
Sbjct: 48 KKRKRGPKKQK----ENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKR 103
Query: 1442 IRKILKDDKLRTETQNALKEEEERRKRIAERE 1473
RK +K +T+ K E + ++ E++
Sbjct: 104 RRK--HREKKEKKTKRRKKGEGDGGQKQVEQK 133
Score = 34.3 bits (77), Expect = 1.6
Identities = 16/30 (53%), Positives = 22/30 (73%)
Query: 1401 KSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430
K + E +E+EEE EEE EEE E+E+E+D
Sbjct: 425 KEGVQWEAKEEEEEYEEEGEEEGEKEEEDD 454
Score = 34.3 bits (77), Expect = 1.6
Identities = 46/210 (21%), Positives = 85/210 (40%), Gaps = 18/210 (8%)
Query: 1182 SSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPV--------TVDDDDDDNDPENRI 1233
+S E++I V + ++ +H G +A S S T + D+N+ EN+
Sbjct: 1188 ASVEERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKE 1247
Query: 1234 AKKMLL----EEIKANLSSDEDGSSDDEPEEGKKRTGK-QNEENPGDEEAKNQVNSESDS 1288
++ E I L ++D + D + + + + + EE K +
Sbjct: 1248 EDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREII 1307
Query: 1289 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE 1348
EE+ P Y +LLRH + E+ + K V+ + ++++ +D+ +
Sbjct: 1308 KQEENVDPDYWEKLLRHHYE----QQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEY 1363
Query: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQ 1378
S SEE E DE RP R K +L +
Sbjct: 1364 SVGSEEEDEDFDE-RPEGRRQSKRQLRNEK 1392
Score = 33.5 bits (75), Expect = 2.6
Identities = 25/108 (23%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Query: 979 EKLPEREEICHFPK--GIKQIKNG------TTDGEKKSKKIRDKTSKKKDELSDYAEKST 1030
+++P++++I P G+K+ K G G+ + +K RD + E +Y EKS
Sbjct: 30 DRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSE 89
Query: 1031 GKGDSCDSSEDKKSKNGAYGREKKRCKLL----GKSSRKRQDCSSSDT 1074
G + +K + +++K+ K G +K+ + SS T
Sbjct: 90 SGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSAT 137
Score = 33.5 bits (75), Expect = 2.6
Identities = 15/24 (62%), Positives = 19/24 (79%)
Query: 1408 EEEKEEEEEEEEEEEEEEEDENDD 1431
E ++EEEE EEE EEE E++E DD
Sbjct: 431 EAKEEEEEYEEEGEEEGEKEEEDD 454
Score = 33.1 bits (74), Expect = 3.5
Identities = 37/191 (19%), Positives = 83/191 (43%), Gaps = 10/191 (5%)
Query: 1299 RHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE-SGVSEEVSE 1357
R +L H L V G + +E ++ ++ +++E + +E S V +E
Sbjct: 1200 RKMMLTH-LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNE 1258
Query: 1358 SEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV-QEDSSSENKSNSEEEEEEKEEEEE 1416
+ R + A + +N Y K + V +ED E + ++EE + +
Sbjct: 1259 AIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYW 1318
Query: 1417 EEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN-------ALKEEEERRKRI 1469
E+ E+ + D +++ GKG++ +++ +D + + N + +E+E+ +R
Sbjct: 1319 EKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERP 1378
Query: 1470 AEREREREKLR 1480
R + + +LR
Sbjct: 1379 EGRRQSKRQLR 1389
Score = 32.7 bits (73), Expect = 4.5
Identities = 16/54 (29%), Positives = 22/54 (40%), Gaps = 7/54 (12%)
Query: 180 EQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPE 233
+ C C +GG +I CD C A+ C+ L R +W C C E
Sbjct: 380 DYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRA-------PEGKWSCPHCEKE 426
Score = 32.3 bits (72), Expect = 5.9
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 1395 DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKD 1448
D + E K + E+E + E +EEEEE EEE E + K + ++ KD
Sbjct: 411 DRAPEGKWSCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKD 464
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 120 bits (300), Expect = 2e-26
Identities = 90/278 (32%), Positives = 141/278 (50%), Gaps = 30/278 (10%)
Query: 1975 VLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYK 2034
+++ SGK++LL ++LR +E G +VL+FSQ LDL+EDFL+ Y+
Sbjct: 1114 LIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLD---------------YE 1158
Query: 2035 GEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRV 2094
G Y R+DG T R++ + FN + F++ST+AG LGINL A+ V
Sbjct: 1159 G-------YKYERIDGGITGALRQEAIDRFN-APGAQQFCFLLSTRAGGLGINLATADTV 1210
Query: 2095 IIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQ 2154
IIFD+ WNP DIQ+ R +R GQ V +YRF+ + ++E++I K L+ VV
Sbjct: 1211 IIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRP 1270
Query: 2155 QQVERHFTMN--ELTELYTF-EPDLLDDPNSEKKKKRDTPMLPKDT-ILAELL---QIHK 2207
+ +M+ EL ++ F +L D N + K+ D+ ++ D +A LL Q
Sbjct: 1271 GLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDAT 1330
Query: 2208 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKK 2245
E + ++ L K + + EE K E E K+
Sbjct: 1331 EDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQ 1368
Score = 92.8 bits (229), Expect = 4e-18
Identities = 99/410 (24%), Positives = 170/410 (41%), Gaps = 52/410 (12%)
Query: 1456 QNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDED----EETKEPL 1511
Q+ +E+E E ++ + RE+I ED + + K L D T +P
Sbjct: 719 QSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPT 778
Query: 1512 VQVHRNMVI------KLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQ 1565
V+ L +Q++G+ ++ + + G+ ILA MGLGKT+Q
Sbjct: 779 VKYETQPRFITATGGTLHMYQLEGLNWL---------RFSWAQGTDTILADEMGLGKTIQ 829
Query: 1566 VVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQ 1625
+ FL++ L + LV PL+T +NW EF+ W + + R
Sbjct: 830 TIVFLYS-LYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIREN 888
Query: 1626 ERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGP------DFVV 1679
E S+ ED + G + + + VK L + +D +V
Sbjct: 889 EFSF------EDNAIK--GGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLV 940
Query: 1680 CDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFR 1739
DE H LKN S + +N + +++LTGTPLQNNL E ++NF+ +++ F
Sbjct: 941 VDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFL 1000
Query: 1740 NRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAV 1799
F + + Q +KK L+++L + R+ + K +P K E ++ V
Sbjct: 1001 EEFADISKEDQ-----------IKK----LHDLLGPHMLRRLKADVFKNMPAKTELIVRV 1045
Query: 1800 RMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPW 1849
++ +Q K Y+Y L N+ GG + + D L + HP+
Sbjct: 1046 ELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMD---LKKCCNHPY 1092
Score = 44.7 bits (104), Expect = 0.001
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Query: 1390 IKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE--EEEEDENDDSKSPGKG 1438
++ +E+ E + EEEEEE+E +EEEEEE E +E+++E+DD G+G
Sbjct: 5 LRDEEEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRG 55
Score = 41.6 bits (96), Expect = 0.010
Identities = 19/47 (40%), Positives = 29/47 (61%)
Query: 1397 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR 1443
S E + EE +EE+EEE E +E++EE++DE + PG R + R
Sbjct: 18 SEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDR 64
Score = 39.3 bits (90), Expect = 0.048
Identities = 18/51 (35%), Positives = 30/51 (58%)
Query: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR 1443
+E+ + EEEE ++EEEEE E +E++EED+++ G G + R
Sbjct: 12 EEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGR 62
Score = 38.1 bits (87), Expect = 0.11
Identities = 48/196 (24%), Positives = 70/196 (35%), Gaps = 55/196 (28%)
Query: 1255 DDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK-----------KPRYRH--- 1300
++E EE ++ EE GDEE + +V + + D E+ + R RH
Sbjct: 9 EEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPP 68
Query: 1301 -----------------------------RLLRHKLTVSDGESGEEKKTKPKEHKEVKGR 1331
RLL L V +++K PK+ KE K
Sbjct: 69 GCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGV------KKRKRGPKKQKENKPG 122
Query: 1332 NRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIK 1391
RK DSE+ E E SES + K+ R K+KK +RR K
Sbjct: 123 KPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKR---RRKHREKKEKKTKRRKK 179
Query: 1392 VQEDSSS---ENKSNS 1404
+ D E KS++
Sbjct: 180 GEGDGGQKQVEQKSSA 195
Score = 38.1 bits (87), Expect = 0.11
Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 8/113 (7%)
Query: 1323 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1382
+E +++ R + E++ D D+ E + + +++ K+ + N
Sbjct: 1353 REEDKIEEIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAA 1412
Query: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
Q+ +D+ SE SEEE+E+ +E E + + + +E D P
Sbjct: 1413 QE--------DQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPP 1457
Score = 37.7 bits (86), Expect = 0.14
Identities = 18/34 (52%), Positives = 23/34 (67%)
Query: 1397 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430
+S + EEEEE EEEEEEEEE +EE+E +
Sbjct: 2 ASPLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEE 35
Score = 37.7 bits (86), Expect = 0.14
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 7/57 (12%)
Query: 174 DSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYIC 230
+ D E CR C +GG L+CCD C +++ C+ L I N +W C C
Sbjct: 510 EEDDHMEYCRVCKDGGELLCCDACISSYHIHCL-----NPPLPDI--PNGEWLCPRC 559
Score = 36.6 bits (83), Expect = 0.31
Identities = 35/155 (22%), Positives = 72/155 (46%), Gaps = 17/155 (10%)
Query: 1310 SDGESGEEKKTKPKEHKEVKGR--NRRKVSSEDSEDSDFQES----GVSEEVSESEDEQR 1363
++GE+ EE + E R +R + ++ED++ + E V++ V ED+
Sbjct: 1300 NEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIE 1359
Query: 1364 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN--------KSNSEEEEEEKEEEE 1415
R K E E Y +K R + Q++ + N K + + +++++
Sbjct: 1360 EIEREIIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDN 1418
Query: 1416 EEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK 1450
+ E EEEDE+ D + +GR++ ++ L+++K
Sbjct: 1419 QSEYSVGSEEEDEDFDERP--EGRRQSKRQLRNEK 1451
Score = 36.2 bits (82), Expect = 0.41
Identities = 41/190 (21%), Positives = 74/190 (38%), Gaps = 33/190 (17%)
Query: 1306 KLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPR 1365
++ VS+ E EE++ +E +EV+ + +D ED D G D P
Sbjct: 14 EMVVSEEEEEEEEEGDEEEEEEVEAADE-----DDEEDDDEGVLGRGPGHDRGRDRHSPP 68
Query: 1366 --------------------TRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSE 1405
K ++ + KK++R K Q+ ENK
Sbjct: 69 GCHLFPPPPPPPPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQK----ENKPGKP 124
Query: 1406 EEEEEKEEEEE--EEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEE 1463
+ ++++ EEE E +E E+ + G GRK+ RK +K +T+ K E
Sbjct: 125 RKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRK--HREKKEKKTKRRKKGEG 182
Query: 1464 ERRKRIAERE 1473
+ ++ E++
Sbjct: 183 DGGQKQVEQK 192
Score = 35.4 bits (80), Expect = 0.70
Identities = 16/25 (64%), Positives = 21/25 (84%)
Query: 1405 EEEEEEKEEEEEEEEEEEEEEEDEN 1429
E +EEE+E EEE EEE E+EEED++
Sbjct: 490 EAKEEEEEYEEEGEEEGEKEEEDDH 514
Score = 34.3 bits (77), Expect = 1.6
Identities = 16/30 (53%), Positives = 22/30 (73%)
Query: 1401 KSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430
K + E +E+EEE EEE EEE E+E+E+D
Sbjct: 484 KEGVQWEAKEEEEEYEEEGEEEGEKEEEDD 513
Score = 34.3 bits (77), Expect = 1.6
Identities = 46/210 (21%), Positives = 85/210 (40%), Gaps = 18/210 (8%)
Query: 1182 SSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPV--------TVDDDDDDNDPENRI 1233
+S E++I V + ++ +H G +A S S T + D+N+ EN+
Sbjct: 1247 ASVEERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKE 1306
Query: 1234 AKKMLL----EEIKANLSSDEDGSSDDEPEEGKKRTGK-QNEENPGDEEAKNQVNSESDS 1288
++ E I L ++D + D + + + + + EE K +
Sbjct: 1307 EDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREII 1366
Query: 1289 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE 1348
EE+ P Y +LLRH + E+ + K V+ + ++++ +D+ +
Sbjct: 1367 KQEENVDPDYWEKLLRHHYE----QQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEY 1422
Query: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQ 1378
S SEE E DE RP R K +L +
Sbjct: 1423 SVGSEEEDEDFDE-RPEGRRQSKRQLRNEK 1451
Score = 33.5 bits (75), Expect = 2.6
Identities = 15/24 (62%), Positives = 19/24 (79%)
Query: 1408 EEEKEEEEEEEEEEEEEEEDENDD 1431
E ++EEEE EEE EEE E++E DD
Sbjct: 490 EAKEEEEEYEEEGEEEGEKEEEDD 513
Score = 33.1 bits (74), Expect = 3.5
Identities = 37/191 (19%), Positives = 83/191 (43%), Gaps = 10/191 (5%)
Query: 1299 RHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE-SGVSEEVSE 1357
R +L H L V G + +E ++ ++ +++E + +E S V +E
Sbjct: 1259 RKMMLTH-LVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENEGENKEEDSSVIHYDNE 1317
Query: 1358 SEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV-QEDSSSENKSNSEEEEEEKEEEEE 1416
+ R + A + +N Y K + V +ED E + ++EE + +
Sbjct: 1318 AIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYW 1377
Query: 1417 EEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN-------ALKEEEERRKRI 1469
E+ E+ + D +++ GKG++ +++ +D + + N + +E+E+ +R
Sbjct: 1378 EKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERP 1437
Query: 1470 AEREREREKLR 1480
R + + +LR
Sbjct: 1438 EGRRQSKRQLR 1448
Score = 32.7 bits (73), Expect = 4.5
Identities = 16/54 (29%), Positives = 22/54 (40%), Gaps = 7/54 (12%)
Query: 180 EQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYICHPE 233
+ C C +GG +I CD C A+ C+ L R +W C C E
Sbjct: 439 DYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRA-------PEGKWSCPHCEKE 485
Score = 32.7 bits (73), Expect = 4.5
Identities = 93/552 (16%), Positives = 205/552 (37%), Gaps = 87/552 (15%)
Query: 888 GKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS 947
G E+ F + E H + ++ D D E ++ ++ S K +
Sbjct: 1291 GTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSF--KVA 1348
Query: 948 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK 1007
+ E+ K + ++++IK E+ + D EKL H+ + + + G++
Sbjct: 1349 QYVVREEDKIEEIEREIIKQEENVDP--DYWEKLLRH----HYEQQQEDLARNLGKGKRV 1402
Query: 1008 SKKIR--DKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK----------- 1054
K++ D + +D S+Y+ S + + D + + ++ R +K
Sbjct: 1403 RKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPPLLARV 1462
Query: 1055 --RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSS-----KRN 1107
++LG ++R+R+ ++ ++ M ++ ++ + + + + R+
Sbjct: 1463 GGNIEVLGFNTRQRKAFLNA-VMRWGMPPQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRH 1521
Query: 1108 TKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSS 1167
E + S + A+ + ++Q + +VK+K + + + ++ S
Sbjct: 1522 LCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPS 1581
Query: 1168 SDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDN 1227
+D + + +S K P T ++S + S P T +
Sbjct: 1582 ADSKRSSR------ASSPTKTSPTTP-----------EASATNSPCTSKPATPAPSEKG- 1623
Query: 1228 DPENRIAKKMLLEEIKANLSSDEDGSSDDEPEE----GKKRTGKQNEENP----GDEEAK 1279
E I+ L +E + +++PE+ G+K + + +P G+
Sbjct: 1624 ------------EGIRTPLEKEEAENQEEKPEKNSRIGEKMETEADAPSPAPSLGERLEP 1671
Query: 1280 NQVNSESDSDS---EESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKV 1336
++ E + E +P YR + + GE GEEK +EH+E
Sbjct: 1672 RKIPLEDEVPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRE--------- 1722
Query: 1337 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDS 1396
+ E D G E+V + + E RP R ++ +R K +K R + +
Sbjct: 1723 -RPEGETGDL---GKREDV-KGDRELRPGPRDEPRS---NGRREEKTEKPRFMFNIADGG 1774
Query: 1397 SSENKSNSEEEE 1408
+E + + EE
Sbjct: 1775 FTELHTLWQNEE 1786
Score = 32.3 bits (72), Expect = 5.9
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 1395 DSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKD 1448
D + E K + E+E + E +EEEEE EEE E + K + ++ KD
Sbjct: 470 DRAPEGKWSCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKD 523
>gi|164419749 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform b [Homo sapiens]
Length = 1042
Score = 120 bits (300), Expect = 2e-26
Identities = 68/183 (37%), Positives = 104/183 (56%), Gaps = 23/183 (12%)
Query: 1972 DAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPL 2031
D ++ +SGKMV+L ++L +E G +VL+FSQ LD++ED+
Sbjct: 478 DEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYC--------------- 522
Query: 2032 IYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAA 2091
W R +Y RLDG T + R++ E FN N +F++ST+AG LGINL +A
Sbjct: 523 ------MW-RGYEYCRLDGQTPHEEREEAIEAFN-APNSSKFIFMLSTRAGGLGINLASA 574
Query: 2092 NRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRV 2151
+ VI++D+ WNP D+Q++ R +R GQ KPV V+R + T+E++I +R K L V
Sbjct: 575 DVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIV 634
Query: 2152 VDQ 2154
+ Q
Sbjct: 635 IQQ 637
Score = 92.8 bits (229), Expect = 4e-18
Identities = 124/526 (23%), Positives = 211/526 (40%), Gaps = 97/526 (18%)
Query: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL--EENQRSYKQKKKRRRIKVQ 1393
+ E S QE G + +E+ T + +K E E+N S++ K + K
Sbjct: 24 IEDEQPGPSTSQEEGAAAAATEA-------TAATEKGEKKKEKNVSSFQLKLAAKAPK-- 74
Query: 1394 EDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE-----DENDDSKSPGKGRKKIRKILKD 1448
SE + + E EE+ K + + E ++ E + KSP + L
Sbjct: 75 ----SEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSP---TSPLNMKLGR 127
Query: 1449 DKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETK 1508
+++ + + +L + R R E+E + E L E S + + +
Sbjct: 128 PRIKKDEKQSLISAGDYRHRRTEQEEDEELLSE-------SRKTSNVCIRFEVSPSYVKG 180
Query: 1509 EPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVS 1568
PL + +Q+ G+ ++ G ILA MGLGKTLQ ++
Sbjct: 181 GPL-----------RDYQIRGLNWLISLY---------ENGVNGILADEMGLGKTLQTIA 220
Query: 1569 FLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLK-----DDEKLEVSELATVKR 1623
L + + +V+ P +T NWMNEF++W L+ D+ + +
Sbjct: 221 LLGYLKHYRNIP-GPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMM 279
Query: 1624 PQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEG 1683
P E W V + YEM +K + + + F+ ++V DE
Sbjct: 280 PGE-------WD----VCVTSYEMV--------IKEKSVFKKFHWR-------YLVIDEA 313
Query: 1684 HILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFI 1743
H +KNE S +S+ + +S R++LTGTPLQNNL E ++NF+ ++ S +F + F
Sbjct: 314 HRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWF- 372
Query: 1744 NPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTS 1803
C +K L+ +L + R+ T + K LPPK E + + ++
Sbjct: 373 ---DTKNCLGD--------QKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSK 421
Query: 1804 IQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPW 1849
+Q + Y L V NS G K +L L + HP+
Sbjct: 422 MQREWYTKILMKDIDV-LNSSGKMDK--MRLLNILMQLRKCCNHPY 464
>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a5 [Homo sapiens]
Length = 1052
Score = 119 bits (298), Expect = 4e-26
Identities = 69/183 (37%), Positives = 103/183 (56%), Gaps = 23/183 (12%)
Query: 1972 DAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPL 2031
D ++ +SGKMV+L ++L +E G +VL+FSQ LD++ED+
Sbjct: 475 DMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYC--------------- 519
Query: 2032 IYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAA 2091
W RN +Y RLDG T R+ +N E N +F++ST+AG LGINL A
Sbjct: 520 ------MW-RNYEYCRLDGQTPHDERQDSINAYN-EPNSTKFVFMLSTRAGGLGINLATA 571
Query: 2092 NRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRV 2151
+ VI++D+ WNP D+Q++ R +R GQTK V V+RF+ T+E++I +R K L V
Sbjct: 572 DVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIV 631
Query: 2152 VDQ 2154
+ Q
Sbjct: 632 IQQ 634
Score = 94.7 bits (234), Expect = 1e-18
Identities = 116/481 (24%), Positives = 197/481 (40%), Gaps = 80/481 (16%)
Query: 1390 IKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDD 1449
+ Q +S+ + ++ E EE ++ +++E +E D + K + +LK
Sbjct: 40 VAAQAVASAVSAGPADAEMEEIFDDASPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQT 99
Query: 1450 KL--------RTETQNALKEEEERRKRIAERERE--------REKLREVIEIEDASPTKC 1493
+L +T + + + R RI + E++ R + E E E+
Sbjct: 100 ELFAHFIQPAAQKTPTSPLKMKPGRPRIKKDEKQNLLSVGDYRHRRTEQEEDEELLTESS 159
Query: 1494 PITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCI 1553
T ED + KL+ +QV G+ ++ G I
Sbjct: 160 KATNVCTRFEDSPSYVKWG--------KLRDYQVRGLNWLISLY---------ENGINGI 202
Query: 1554 LAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKD---- 1609
LA MGLGKTLQ +S L + + +V+ P +T NWM+EF++W L+
Sbjct: 203 LADEMGLGKTLQTISLLGYMKHYRNIP-GPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLI 261
Query: 1610 -DEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNK 1668
D++ + + V P E W V + YEM +K + + + FN
Sbjct: 262 GDKEQRAAFVRDVLLPGE-------WD----VCVTSYEML--------IKEKSVFKKFNW 302
Query: 1669 ALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIK 1728
++V DE H +KNE S +S+ + ++ R++LTGTPLQNNL E ++NF+
Sbjct: 303 R-------YLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLL 355
Query: 1729 ENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKF 1788
++ S +F + F N D +V+ M R +L R+ + K
Sbjct: 356 PDVFNSADDFDSWFDT---NNCLGDQKLVERLHMVLRPFLL---------RRIKADVEKS 403
Query: 1789 LPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHP 1848
LPPK E + V ++ +Q + Y L + NS G K +L L + HP
Sbjct: 404 LPPKKEVKIYVGLSKMQREWYTRILMKDIDI-LNSAGKMDK--MRLLNILMQLRKCCNHP 460
Query: 1849 W 1849
+
Sbjct: 461 Y 461
>gi|21914927 helicase, lymphoid-specific [Homo sapiens]
Length = 838
Score = 119 bits (298), Expect = 4e-26
Identities = 75/230 (32%), Positives = 121/230 (52%), Gaps = 29/230 (12%)
Query: 1972 DAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPL 2031
D E++ +SGK ++L +L ++ G KVL+FSQ LD++ D+ L
Sbjct: 591 DEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHL------------- 637
Query: 2032 IYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAA 2091
R+ ++ RLDGS + R+K FN + V +F++ST+AG LGINL AA
Sbjct: 638 ---------RDFNFSRLDGSMSYSEREKNMHSFNTDPEVF--IFLVSTRAGGLGINLTAA 686
Query: 2092 NRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRV 2151
+ VII+D+ WNP D+Q+ R +R GQTKPV VYR + T++ KI +R K+ L +
Sbjct: 687 DTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLI 746
Query: 2152 VDQQQVERHFTMNELTELYTFEPDLLD-----DPNSEKKKKRDTPMLPKD 2196
+ + + + L++ + +L++ D E K R+ + KD
Sbjct: 747 IHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKD 796
Score = 89.7 bits (221), Expect = 3e-17
Identities = 105/476 (22%), Positives = 202/476 (42%), Gaps = 89/476 (18%)
Query: 1347 QESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEE 1406
++S + + ++ EQ+ KK +LE + S K KK + I E+ K E
Sbjct: 73 EKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGRE 132
Query: 1407 EEE-------EKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNAL 1459
+E KEE ++ ++E EDEN S + + +D + + N++
Sbjct: 133 DESYNISEVMSKEEILSVAKKNKKENEDENSSSTN----------LCVEDLQKNKDSNSI 182
Query: 1460 KEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETK---EPLVQVHR 1516
++ R++E R+ TK D + P Q
Sbjct: 183 IKD-----RLSETVRQ--------------------NTKFFFDPVRKCNGQPVPFQQPKH 217
Query: 1517 NMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLC 1576
++ +QV+G++++ + G ILA MGLGKT+Q ++ T+ L
Sbjct: 218 FTGGVMRWYQVEGMEWL---------RMLWENGINGILADEMGLGKTVQCIA---TIALM 265
Query: 1577 DKLDFSTALVVC-PLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQ 1635
+ +VC PL+T NWM EF+++ ++ + +ER +++
Sbjct: 266 IQRGVPGPFLVCGPLSTLPNWMAEFKRFTP--------DIPTMLYHGTQEERQKLVRNIY 317
Query: 1636 EDGG------VMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNE 1689
+ G V+I +E+ + RN L+ + K +++ DEGH +KN
Sbjct: 318 KRKGTLQIHPVVITSFEI---AMRDRNA----LQHCYWK--------YLIVDEGHRIKNM 362
Query: 1690 ASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNG 1749
+ + + + +++LTGTPLQNNL E ++NF+ ++ +K F + F +
Sbjct: 363 KCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWF-DITSLS 421
Query: 1750 QCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQ 1805
+ A+ + R + H+L+++L + R+ + + +PPK E V+ ++ Q
Sbjct: 422 ETAEDIIAKER-EQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQ 476
Score = 35.4 bits (80), Expect = 0.70
Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 20/167 (11%)
Query: 1079 MKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKK 1138
M E S D+ I R ++L K N I S + E+ + +KKK++ KK
Sbjct: 48 MLEKARMSWDRESTEIRYRRLQHLLEKSN---IYSKFLLTKMEQQQLEEQKKKEKLERKK 104
Query: 1139 KAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLS 1198
+++ VK K +NS+ S ++ ED+ N I E S E+ + +N
Sbjct: 105 ESLKVK-KGKNSIDASEEKP----VMRKKRGREDESYN-ISEVMSKEEILSVAKKN---- 154
Query: 1199 SHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKAN 1245
+ ++ S S + V+D + D N I K L E ++ N
Sbjct: 155 ------KKENEDENSSSTNLCVEDLQKNKD-SNSIIKDRLSETVRQN 194
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 118 bits (296), Expect = 6e-26
Identities = 85/296 (28%), Positives = 142/296 (47%), Gaps = 55/296 (18%)
Query: 1975 VLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYK 2034
++ SGK++LL ++L E G++VL+FSQ + LD++ ++L +
Sbjct: 786 LIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTI---------------- 829
Query: 2035 GEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRV 2094
++ + RLDGS + RK+ + FN + + F++ST+AG LGINL +A+ V
Sbjct: 830 ------KHYPFQRLDGSIKGEIRKQALDHFNADGS-EDFCFLLSTRAGGLGINLASADTV 882
Query: 2095 IIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQ 2154
+IFD+ WNP D+Q+ R +R GQ K V +YR + +GT+E++I +R K L V+ +
Sbjct: 883 VIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQR 942
Query: 2155 QQV--------------ERHFTMNELTELYTF-EPDLLDDPNSEKKKKRDTPMLPKDTIL 2199
F ELT + F DL + E+ + P++ +
Sbjct: 943 MDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESE-------PQEMDI 995
Query: 2200 AELLQI--HKEHIVGYHEHDSLLDH--------KEEEELTEEERKAAWAEYEAEKK 2245
E+L++ +E+ V D LL E+EE EE W E E++
Sbjct: 996 DEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQ 1051
Score = 91.3 bits (225), Expect = 1e-17
Identities = 161/833 (19%), Positives = 306/833 (36%), Gaps = 130/833 (15%)
Query: 1007 KSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKR 1066
K K + +S + S A + DS SE ++ + G + SS
Sbjct: 5 KDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSES----NSSSESS 60
Query: 1067 QDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQS--GSSSSDAEESS 1124
+ S S++E K K ++ ++ R K+ +E G S+
Sbjct: 61 ESQSESESESAGSKSQPVLPEAK--EKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQE 118
Query: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184
K+ SS ++ K + + L+ K KQ ++ +Q + E +
Sbjct: 119 PSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQ-------EPSEDEQEQGTSAESEPE 171
Query: 1185 EQKIK---PVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEE 1241
++K+K PV V + K D D++D ++ K+
Sbjct: 172 QKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQ------DSSDEDDDDDEAPKRQTRRR 225
Query: 1242 IKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHR 1301
N+S ED + + ++ + TG+ DE+ N E DS KK
Sbjct: 226 AAKNVSYKEDDDFETDSDDLIEMTGE-----GVDEQQDNSETIEKVLDSRLGKKGATGAS 280
Query: 1302 LLRHKLTVSDGESG--EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVS-----EE 1354
+ + + SG + +K + + +K + + S + Q+ V E
Sbjct: 281 TTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLEN 340
Query: 1355 VSESEDEQRPRTRSAKKAELEE---NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK 1411
+ EDE + ++E Q + K+ +I + + +KS + +
Sbjct: 341 FKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPA 400
Query: 1412 EEEEEEEEEEEE----------EEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKE 1461
+ E E E D++ K + I + +T K
Sbjct: 401 HSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKA 460
Query: 1462 EEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIK 1521
++R + +A +++ E +E+ D
Sbjct: 461 LKQRPRFVALKKQPAYLGGENLELRD---------------------------------- 486
Query: 1522 LKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDF 1581
+Q++G+ ++ C++ + ILA MGLGKT+Q +SFL + +L +
Sbjct: 487 ---YQLEGLNWLAHSWCKN---------NSVILADEMGLGKTIQTISFLSYLFHQHQL-Y 533
Query: 1582 STALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYM-LQRWQEDGGV 1640
L+V PL+T +W EFE W + + + + +L + +E ++ Q +
Sbjct: 534 GPFLIVVPLSTLTSWQREFEIWAPEI--NVVVYIGDLMSRNTIREYEWIHSQTKRLKFNA 591
Query: 1641 MIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSI 1700
+I YE+ +K + + N A F+ DE H LKN+ S + K +
Sbjct: 592 LITTYEIL--------LKDKTVLGSINWA-------FLGVDEAHRLKNDDSLLYKTLIDF 636
Query: 1701 RSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVR 1760
+S R+++TGTPLQN+L E +++FI ++F +NG
Sbjct: 637 KSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGY---------- 686
Query: 1761 VMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYL 1813
L+++L + R+ + K LP K E +L V M+++Q + Y++ L
Sbjct: 687 ------QSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWIL 733
Score = 52.8 bits (125), Expect = 4e-06
Identities = 85/387 (21%), Positives = 147/387 (37%), Gaps = 82/387 (21%)
Query: 1103 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQR---TSSKKKAV----------IVKEKKRN 1149
S + ++ Q S+S E S+D+KK K+R S +K V +K K+
Sbjct: 1087 SDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKF 1146
Query: 1150 SL---RTSTKRKQADITSSSSSDI------------------EDDDQNSIGEGSSDEQKI 1188
L R + A++ S +D+ E+ + + EG ++
Sbjct: 1147 GLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRR 1206
Query: 1189 KPVTE--NLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANL 1246
P + + ++ + E L KS+PV DPE + K L +KA
Sbjct: 1207 GPTIKISGVQVNVKSIIQHEEEFEMLHKSIPV---------DPEEK-KKYCLTCRVKAAH 1256
Query: 1247 SSDEDGSSDD--------EPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRY 1298
E G DD E G K + E ++ + + + Y
Sbjct: 1257 FDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADY 1316
Query: 1299 RHRLLRHKL----TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEE 1354
+LLR L V+ GE + KK KP+ KE K + +E G+ E
Sbjct: 1317 LLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLK------------EEHGI--E 1362
Query: 1355 VSESEDEQRPRTRSAKKAE-LEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEE 1413
+S P K + LE++ KQKKK + ENK ++KE
Sbjct: 1363 LSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENK---------ENKEKQMSSRKDKEG 1413
Query: 1414 EEEEEEEEEEEEEDENDDSKSPGKGRK 1440
++E ++ ++++E+ ++ D+KS K ++
Sbjct: 1414 DKERKKSKDKKEKPKSGDAKSSSKSKR 1440
Score = 50.4 bits (119), Expect = 2e-05
Identities = 51/278 (18%), Positives = 121/278 (43%), Gaps = 45/278 (16%)
Query: 1268 QNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE 1327
+N++ +E++ N+ S S SEE+ G E ++
Sbjct: 3 RNKDKSQEEDSSLHSNASSHSASEEASGS-------------DSGSQSESEQGSDPGSGH 49
Query: 1328 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEEN---------- 1377
N SSE +S+ + +G + E +++P ++ + A++++
Sbjct: 50 GSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGV 109
Query: 1378 QRSYKQKKKRRRIKVQEDSSSENKSNSEE-------EEEEKEEEEEEEEEEEEEEEDEND 1430
+RS + +++ R ++E++SS ++S S + +++EK ++E E+E+E+ E++
Sbjct: 110 RRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE 169
Query: 1431 DSKSPGKGRK----------KIRKILKDDKLRTETQNALKE----EEERRKRIAERERER 1476
+ K R+ +++K K + + + Q++ E +E +++ R +
Sbjct: 170 PEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKN 229
Query: 1477 EKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQV 1514
+E + E S +T + V DE ++ E + +V
Sbjct: 230 VSYKEDDDFETDSDDLIEMTGEGV-DEQQDNSETIEKV 266
Score = 48.5 bits (114), Expect = 8e-05
Identities = 38/161 (23%), Positives = 71/161 (44%), Gaps = 14/161 (8%)
Query: 1311 DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSED--SDFQESGVSEEVSESEDEQRPRT-- 1366
+GE E ++ E + +VS+ +++ S F+ + + E E E+RP
Sbjct: 984 EGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDW 1043
Query: 1367 ------RSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1420
KK E EE Q+ ++ RI+ S+ + ++N + + E + + +
Sbjct: 1044 DEIIPEEQRKKVEEEERQKELEEIYMLPRIR---SSTKKAQTNDSDSDTESKRQAQRSSA 1100
Query: 1421 EEEEEEDENDDSKSPGKGR-KKIRKILKDDKLRTETQNALK 1460
E E ED +DD K +GR + +RK L + E + +K
Sbjct: 1101 SESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIK 1141
Score = 38.5 bits (88), Expect = 0.082
Identities = 120/637 (18%), Positives = 236/637 (37%), Gaps = 126/637 (19%)
Query: 885 KLSGKE---QSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSE 941
+L G+E Q E+ ++AET+E ++ +F K + T E
Sbjct: 982 ELEGEESEPQEMDIDEILRLAETRENEVSTSAT---------DELLSQF--KVANFATME 1030
Query: 942 DDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPK---GIKQIK 998
D++ E +++P ++I EQ+ + + +K E EEI P+ K+ +
Sbjct: 1031 DEE-------ELEERPHKDWDEIIPEEQRKKVEEEERQK--ELEEIYMLPRIRSSTKKAQ 1081
Query: 999 NGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKL 1058
+D + +SK+ ++S + E D + K S K G E +R
Sbjct: 1082 TNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIK 1141
Query: 1059 LGKS---SRKRQDCSSSDTEKYS-----MKEDG---CNSSDKRLKRIELRERRNLSSKRN 1107
K +R +C + D E +K G NS ++ E + + N S +
Sbjct: 1142 AYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKG 1201
Query: 1108 TKEIQSGS---SSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITS 1164
+ + + S S +++ K V +EKK+ L K D+
Sbjct: 1202 PGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEW 1261
Query: 1165 SSSSDIEDDDQNSIG---EGSSDEQKIKP-----VTENLV------------LSSHTGFC 1204
+EDD + +G G + + IK +T+ ++ L + +
Sbjct: 1262 G----VEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYL 1317
Query: 1205 QSSGDEALSKSVPVTVDDDDDDNDPENRIAKK----MLLEEIKANLSSDEDGSSDDEPEE 1260
+ L K VT ++ + R+ K+ L EE LSS SD+ EE
Sbjct: 1318 LKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRH--SDNPSEE 1375
Query: 1261 G-------------KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL 1307
G KK+ K+N+EN + Q++S D + ++ +K + + + K
Sbjct: 1376 GEVKDDGLEKSPMKKKQKKKENKENK-----EKQMSSRKDKEGDKERK---KSKDKKEKP 1427
Query: 1308 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR 1367
D +S + K G + ++ +D D E S ++ RP +
Sbjct: 1428 KSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLD------QETFSICKERMRPVKK 1481
Query: 1368 SAKKAELEENQRSYKQKKKRRR---IKVQEDSSSENKSNSEEEE---------------- 1408
+ K+ + + + +++ + R +K+ + + K+ S++E
Sbjct: 1482 ALKQLDKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFT 1541
Query: 1409 ----------EEKEEEEEEEEEEEEEEEDENDDSKSP 1435
+ ++ +EEEE++++D+ K P
Sbjct: 1542 EFDARKLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKP 1578
Score = 37.7 bits (86), Expect = 0.14
Identities = 52/274 (18%), Positives = 103/274 (37%), Gaps = 35/274 (12%)
Query: 706 MSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSII 765
M + S + + +H+N + + +G D SGS ++++G S
Sbjct: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSD-----------SGSQSESEQGSDPGSGHG 50
Query: 766 SKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHS---KKGM 822
S+ ++S S +SE E A ++ +P K+ +S+ E+ + K
Sbjct: 51 SESNSSSESSESQSESESE---------SAGSKSQPVLPEAKEKPASKKERIADVKKMWE 101
Query: 823 DNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDG 882
+ ++ S + + + E S +E K +L+ + KQ+ S
Sbjct: 102 EYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE 161
Query: 883 VDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSED 942
+ E ++ R+ + K + K K Q G K K+D SDE +D
Sbjct: 162 QGTSAESEPEQKKVKARRPVPRRTVPKP-RVKKQPKTQRG------KRKKQDSSDEDDDD 214
Query: 943 DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSD 976
D+ ++ K +K+ + +E+ SD
Sbjct: 215 DEAPKRQTRRRAAKNVSYKE-----DDDFETDSD 243
Score = 37.0 bits (84), Expect = 0.24
Identities = 104/535 (19%), Positives = 195/535 (36%), Gaps = 66/535 (12%)
Query: 594 ENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKL 653
E S+ + + +E+ L E + S L + N T +EE E +
Sbjct: 986 EESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDE 1045
Query: 654 SVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSD 713
+P ++ K + + + LP+ + S Q +DSD ++ R S S S
Sbjct: 1046 IIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESET 1105
Query: 714 TDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKG---KSAKSSIISKKK- 769
D DD K KR+ D +G + I + KK
Sbjct: 1106 ED-------------------SDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKF 1146
Query: 770 --RQTQSESSNYDSEL-EKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSK-KGMDNQ 825
+ E D+EL +K + + ++G + ++++ E S+ KG +
Sbjct: 1147 GLPLERLECIARDAELVDKSVADLKRLGEL-IHNSCVSAMQEYEEQLKENASEGKGPGKR 1205
Query: 826 GHKNLKTS--QEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQ---QASAST 880
+K S Q + ++E E + ++ L R+ +
Sbjct: 1206 RGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVED 1265
Query: 881 DGVDKLSGKEQSFTSLEVRKV-AETKEKSKHLKTKTCKKVQ--------DGLSDIAEKFL 931
D L E + + E+ K E K K L +T KK Q D L + K L
Sbjct: 1266 DSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGL 1325
Query: 932 KKDQSDETSEDDKKQSKKGT--EEKKKPSDFKKKVIKME---------QQYESSSDGTEK 980
+K + E+ K + +K +E K P ++ I++ ++ E DG EK
Sbjct: 1326 EKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEK 1385
Query: 981 LPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSE 1040
P +++ ++ K + EK+ +DK K+ + S ++ GD+ SS+
Sbjct: 1386 SPMKKK--------QKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSK 1437
Query: 1041 DKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIE 1095
K+S+ + +G+ + D E +S+ ++ K LK+++
Sbjct: 1438 SKRSQGPVHITAGSEPVPIGE-----DEDDDLDQETFSICKERMRPVKKALKQLD 1487
Score = 34.7 bits (78), Expect = 1.2
Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 9/96 (9%)
Query: 1382 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS--KSPGKGR 1439
K KK++ R+K ENK +EE E + EE + DD KSP K +
Sbjct: 1338 KLKKRKPRVK------KENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKK 1391
Query: 1440 KKIRKILKDDKLRTETQNALKEEEERRKRIAERERE 1475
+K +K K++K + + KE ++ RK+ +++ +
Sbjct: 1392 QK-KKENKENKEKQMSSRKDKEGDKERKKSKDKKEK 1426
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 116 bits (291), Expect = 2e-25
Identities = 136/552 (24%), Positives = 235/552 (42%), Gaps = 84/552 (15%)
Query: 1326 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY---- 1381
KE K R RRK +E E+++ ES + + ++ + K E + +
Sbjct: 554 KEKKKRRRRKKKAE--ENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEA 611
Query: 1382 -KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1440
K + +++ +S+SEE + + EEE+EEEE +E E+
Sbjct: 612 PKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEE------------- 658
Query: 1441 KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLV 1500
KIL D ++ K+ E K+ + E + A ++ T
Sbjct: 659 ---KILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQY--------SARGSQSYYTVAHA 707
Query: 1501 LDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGL 1560
+ E E + L+ + LK +Q+ G+++M ++ ILA MGL
Sbjct: 708 ISERVEKQSALL-----INGTLKHYQLQGLEWMVSLYNNNLNG---------ILADEMGL 753
Query: 1561 GKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELAT 1620
GKT+Q ++ + T L+ K L++ PL+T NW EF+KW + +++S T
Sbjct: 754 GKTIQTIALI-TYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSV-----VKISYKGT 807
Query: 1621 VKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVC 1680
RS + Q V++ YE +K + + L +++
Sbjct: 808 --PAMRRSLVPQLRSGKFNVLLTTYEYI--------IKDKHI-------LAKIRWKYMIV 850
Query: 1681 DEGHILKNEASAVSKAMNS-IRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFR 1739
DEGH +KN +++ +N+ + RRI+LTGTPLQN L E ++NF+ + S F
Sbjct: 851 DEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFE 910
Query: 1740 NRFINPI-QNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLA 1798
F P G+ D + ++ +R H ++L + R+ + LP K EYV+
Sbjct: 911 QWFNAPFAMTGERVDLNEEETILIIRRLH---KVLRPFLLRRLKKEVESQLPEKVEYVIK 967
Query: 1799 VRMTSIQCKLYQYYLDHLTGVG-----NNSEGGRGKAGAK-LFQDFQMLSRIWTHPWCLQ 1852
M+++Q LY+ H+ G + + +GK GAK L L +I HP+ Q
Sbjct: 968 CDMSALQKILYR----HMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQ 1023
Query: 1853 -LDYISKENKGY 1863
++ E+ GY
Sbjct: 1024 HIEESFAEHLGY 1035
Score = 97.1 bits (240), Expect = 2e-19
Identities = 79/285 (27%), Positives = 134/285 (47%), Gaps = 41/285 (14%)
Query: 1973 AEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLI 2032
AE+ SGK LL IL +VL+F Q + ++ED+
Sbjct: 1043 AELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAF-------------- 1088
Query: 2033 YKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAAN 2092
RN Y RLDG+T ++ R ++FN E + +F++ST+AG LG+NL AA+
Sbjct: 1089 --------RNFLYLRLDGTTKSEDRAALLKKFN-EPGSQYFIFLLSTRAGGLGLNLQAAD 1139
Query: 2093 RVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVV 2152
V+IFD+ WNP D+Q+ R +R GQ V V R ++E+KI K ++ +V+
Sbjct: 1140 TVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1199
Query: 2153 DQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVG 2212
++ + +E F +L+ + E+ ++ D +P D L +++ +E
Sbjct: 1200 QAGMFDQKSSSHERR---AFLQAILE--HEEENEEEDE--VPDDETLNQMIARREEEFDL 1252
Query: 2213 YHEHDSLLDHKEEE--------ELTEEERKAAW-AEYEAEKKGLT 2248
+ D +D + E+ L EE+ +W + +AE + LT
Sbjct: 1253 FMRMD--MDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLT 1295
Score = 48.9 bits (115), Expect = 6e-05
Identities = 52/245 (21%), Positives = 108/245 (44%), Gaps = 14/245 (5%)
Query: 1235 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEE--NPGDEEAKNQVNSESDSDSEE 1292
+++ L++ K + D+D + +D E+ KKR G+ E +P + Q+N+ D+
Sbjct: 1339 EEVRLKKRKRRRNVDKDPAKEDV-EKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINY 1397
Query: 1293 SKKPRYRHRLLRHKLTVSDGESGEE----------KKTKPKEHKEVKGRNRRKVSSEDSE 1342
+ +L + SG + +K P+ ++ ++ K E
Sbjct: 1398 KDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIR 1457
Query: 1343 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS 1402
+ ++ G E+ +T + + +++ E+ + K R K+ ++ SE++S
Sbjct: 1458 NHKYRSLGDLEK-DVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDES 1516
Query: 1403 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE 1462
N EEEEE++EE E E + + + + D K KG+ K R K ++ +E+
Sbjct: 1517 NEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQ 1576
Query: 1463 EERRK 1467
+ER +
Sbjct: 1577 DEREQ 1581
Score = 37.7 bits (86), Expect = 0.14
Identities = 52/255 (20%), Positives = 99/255 (38%), Gaps = 20/255 (7%)
Query: 933 KDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPK 992
KD + E E KK+ + EK P+ K+ +Q + D +R + P
Sbjct: 1354 KDPAKEDVEKAKKRRGRPPAEKLSPNP-----PKLTKQMNAIIDTVINYKDRCNVEKVPS 1408
Query: 993 GIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSED-KKSKNGAYGR 1051
+ G + G + S+ S+K EL +Y E D E + K + G
Sbjct: 1409 NSQLEIEGNSSGRQLSEVFIQLPSRK--ELPEYYELIRKPVDFKKIKERIRNHKYRSLGD 1466
Query: 1052 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTK-E 1110
+K LL C ++ T ++++ L+ + R+ ++ + ++ E
Sbjct: 1467 LEKDVMLL---------CHNAQT--FNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDE 1515
Query: 1111 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1170
D EES + K K + KK ++K + R + + + ++ S +
Sbjct: 1516 SNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEE 1575
Query: 1171 EDDDQNSIGEGSSDE 1185
+D+ + S G G+ DE
Sbjct: 1576 QDEREQSEGSGTDDE 1590
Score = 36.6 bits (83), Expect = 0.31
Identities = 49/290 (16%), Positives = 114/290 (39%), Gaps = 22/290 (7%)
Query: 1242 IKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHR 1301
++A L +E+ +DE + + +EE + + D E+++ P+ + R
Sbjct: 1217 LQAILEHEEENEEEDEVPDDETLNQMIARR---EEEFDLFMRMDMDRRREDARNPKRKPR 1273
Query: 1302 LLRHKLTVS---DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSES 1358
L+ S ++ E+ T +E +++ GR R+ D D+ ++ +
Sbjct: 1274 LMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWL------- 1326
Query: 1359 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE-EE 1417
R+ + LEE + + KK++RR V +D + E+ +++ E+
Sbjct: 1327 --------RAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEKLSP 1378
Query: 1418 EEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERERE 1477
+ ++ + D+ K R + K+ + +L E ++ ++ E ++ R+ E
Sbjct: 1379 NPPKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKELPE 1438
Query: 1478 KLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQV 1527
+ + D K I + K+ ++ H L+ Q+
Sbjct: 1439 YYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQI 1488
Score = 35.4 bits (80), Expect = 0.70
Identities = 21/88 (23%), Positives = 41/88 (46%)
Query: 1333 RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV 1392
R+K++ E+ + + E E+ ESE E + K + ++ R + KKR
Sbjct: 1503 RQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGK 1562
Query: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEE 1420
+ S+ S+ E++E E+ E ++E
Sbjct: 1563 AKPVVSDFDSDEEQDEREQSEGSGTDDE 1590
Score = 34.7 bits (78), Expect = 1.2
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 17/154 (11%)
Query: 1341 SEDSDFQESGVSEEVSESEDEQRPRTRSAKKAE----LEENQRSYKQKKKRRRIKVQEDS 1396
S+ +E+ ++E++ + + ++ R R K E + ++ + +K+ + K+Q+ S
Sbjct: 418 SKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLS 477
Query: 1397 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKIL-----KDDKL 1451
+ ++ E E+K+E E E+E E+++ +KK R++ D+ +
Sbjct: 478 KAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYV 537
Query: 1452 RTETQ--------NALKEEEERRKRIAERERERE 1477
T A KE+++RR+R + E E
Sbjct: 538 ANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENAE 571
Score = 33.9 bits (76), Expect = 2.0
Identities = 27/94 (28%), Positives = 36/94 (38%), Gaps = 17/94 (18%)
Query: 2368 QRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLI------------MNPSNYQQ 2415
Q+ ++ QQQ QQQQQQ QQ + P L+ PS Q+
Sbjct: 218 QQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQK 277
Query: 2416 IDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPGPS 2449
+ + P GG P A P + PGPS
Sbjct: 278 LPV-----PAPGGRPSPAPPAAAQPPAAAVPGPS 306
Score = 33.5 bits (75), Expect = 2.6
Identities = 20/97 (20%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 1329 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR 1388
K ++ E+SED +EE E ++E+ + K +++ N++ K + K +
Sbjct: 1500 KSARQKIAKEEESEDES------NEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGK 1553
Query: 1389 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1425
K ++ + + +EE++E E+ E ++E
Sbjct: 1554 GKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE 1590
Score = 33.5 bits (75), Expect = 2.6
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 11/85 (12%)
Query: 631 ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQN 690
E+N DEE +E+ + K+ + + KKD D D K K P +++ V +
Sbjct: 1515 ESNEEEEEEDEEESESEAKSVKVKIKLNKKD-----DKGRDKGKGKKRPNRGKAKPVVSD 1569
Query: 691 SDSDEMLAILKEVSRMSHSSSSDTD 715
DSDE E S S TD
Sbjct: 1570 FDSDE------EQDEREQSEGSGTD 1588
Score = 32.7 bits (73), Expect = 4.5
Identities = 72/404 (17%), Positives = 149/404 (36%), Gaps = 54/404 (13%)
Query: 955 KKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDK 1014
+KP I E++Y + ++ E E + P + E K+ ++ +
Sbjct: 332 QKPQGLDPVEILQEREYRLQARIAHRIQELENL---PGSLPPDLRTKATVELKALRLLNF 388
Query: 1015 TSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDT 1074
+ + E+ + T + +S K+SK RE + + L K + Q+
Sbjct: 389 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTL-REARMTEKLEKQQKIEQE-----R 442
Query: 1075 EKYSMKEDGCNSSDKRLKRIELRERRNLSSK--RNTKEIQSGSSSSDAEESSEDNKKKKQ 1132
++ ++ NS + K + R+++ K + +K + + ++++ E+ E + +K+
Sbjct: 443 KRRQKHQEYLNSILQHAKDFK-EYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKE 501
Query: 1133 RT------SSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQ 1186
R + ++ +KK L ++ + + ++ E + E +
Sbjct: 502 RMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRR 561
Query: 1187 KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANL 1246
+ K EN G+ AL D +P I + + ++ +
Sbjct: 562 RKKKAEENA----------EGGESALGP-----------DGEP---IDESSQMSDLPVKV 597
Query: 1247 SSDEDGSSDDEPEEGK-KRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRH 1305
+ E G PE K + E NPG E A + ESDSD EE + R
Sbjct: 598 THTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSR---- 653
Query: 1306 KLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQES 1349
+ EEK +EV ++ +++ +D D + S
Sbjct: 654 -------QETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYS 690
Score = 32.3 bits (72), Expect = 5.9
Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 11/116 (9%)
Query: 1391 KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK 1450
KV + + KS+S E + E EEE EEE+E +D++ + R++
Sbjct: 1197 KVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARRE--------- 1247
Query: 1451 LRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEE 1506
E ++ + +RR+ A + + +L E E+ +L +E+EE
Sbjct: 1248 --EEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEE 1301
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 116 bits (291), Expect = 2e-25
Identities = 136/552 (24%), Positives = 235/552 (42%), Gaps = 84/552 (15%)
Query: 1326 KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSY---- 1381
KE K R RRK +E E+++ ES + + ++ + K E + +
Sbjct: 554 KEKKKRRRRKKKAE--ENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEA 611
Query: 1382 -KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1440
K + +++ +S+SEE + + EEE+EEEE +E E+
Sbjct: 612 PKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEE------------- 658
Query: 1441 KIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLV 1500
KIL D ++ K+ E K+ + E + A ++ T
Sbjct: 659 ---KILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQY--------SARGSQSYYTVAHA 707
Query: 1501 LDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGL 1560
+ E E + L+ + LK +Q+ G+++M ++ ILA MGL
Sbjct: 708 ISERVEKQSALL-----INGTLKHYQLQGLEWMVSLYNNNLNG---------ILADEMGL 753
Query: 1561 GKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELAT 1620
GKT+Q ++ + T L+ K L++ PL+T NW EF+KW + +++S T
Sbjct: 754 GKTIQTIALI-TYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSV-----VKISYKGT 807
Query: 1621 VKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVC 1680
RS + Q V++ YE +K + + L +++
Sbjct: 808 --PAMRRSLVPQLRSGKFNVLLTTYEYI--------IKDKHI-------LAKIRWKYMIV 850
Query: 1681 DEGHILKNEASAVSKAMNS-IRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFR 1739
DEGH +KN +++ +N+ + RRI+LTGTPLQN L E ++NF+ + S F
Sbjct: 851 DEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFE 910
Query: 1740 NRFINPI-QNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLA 1798
F P G+ D + ++ +R H ++L + R+ + LP K EYV+
Sbjct: 911 QWFNAPFAMTGERVDLNEEETILIIRRLH---KVLRPFLLRRLKKEVESQLPEKVEYVIK 967
Query: 1799 VRMTSIQCKLYQYYLDHLTGVG-----NNSEGGRGKAGAK-LFQDFQMLSRIWTHPWCLQ 1852
M+++Q LY+ H+ G + + +GK GAK L L +I HP+ Q
Sbjct: 968 CDMSALQKILYR----HMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQ 1023
Query: 1853 -LDYISKENKGY 1863
++ E+ GY
Sbjct: 1024 HIEESFAEHLGY 1035
Score = 97.1 bits (240), Expect = 2e-19
Identities = 79/285 (27%), Positives = 134/285 (47%), Gaps = 41/285 (14%)
Query: 1973 AEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLI 2032
AE+ SGK LL IL +VL+F Q + ++ED+
Sbjct: 1043 AELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAF-------------- 1088
Query: 2033 YKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAAN 2092
RN Y RLDG+T ++ R ++FN E + +F++ST+AG LG+NL AA+
Sbjct: 1089 --------RNFLYLRLDGTTKSEDRAALLKKFN-EPGSQYFIFLLSTRAGGLGLNLQAAD 1139
Query: 2093 RVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVV 2152
V+IFD+ WNP D+Q+ R +R GQ V V R ++E+KI K ++ +V+
Sbjct: 1140 TVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1199
Query: 2153 DQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVG 2212
++ + +E F +L+ + E+ ++ D +P D L +++ +E
Sbjct: 1200 QAGMFDQKSSSHERR---AFLQAILE--HEEENEEEDE--VPDDETLNQMIARREEEFDL 1252
Query: 2213 YHEHDSLLDHKEEE--------ELTEEERKAAW-AEYEAEKKGLT 2248
+ D +D + E+ L EE+ +W + +AE + LT
Sbjct: 1253 FMRMD--MDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLT 1295
Score = 47.8 bits (112), Expect = 1e-04
Identities = 55/237 (23%), Positives = 103/237 (43%), Gaps = 16/237 (6%)
Query: 1235 KKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEE--NPGDEEAKNQVNSESDSD-SE 1291
+++ L++ K + D+D + +D E+ KKR G+ E +P + Q+N+ D+ +
Sbjct: 1339 EEVRLKKRKRRRNVDKDPAKEDV-EKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINY 1397
Query: 1292 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR-KVSSEDSEDSDFQESG 1350
+ R + + + E KP + K++K R R K S + D
Sbjct: 1398 KDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLC 1457
Query: 1351 VSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEE 1410
+ + E Q + E+ + K R K+ ++ SE++SN EEEEE+
Sbjct: 1458 HNAQTFNLEGSQ-----------IYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEED 1506
Query: 1411 KEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRK 1467
+EE E E + + + + D K KG+ K R K ++ +E++ER +
Sbjct: 1507 EEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDEREQ 1563
Score = 45.1 bits (105), Expect = 9e-04
Identities = 76/391 (19%), Positives = 164/391 (41%), Gaps = 42/391 (10%)
Query: 943 DKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKN--G 1000
D+K + G ++K S ++ ++ ++E ++ +++P+ E + ++ +
Sbjct: 1195 DQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFM 1254
Query: 1001 TTDGEKKSKKIRDKTSK----KKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRC 1056
D +++ + R+ K ++DEL + K + + E+++
Sbjct: 1255 RMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEE------------- 1301
Query: 1057 KLLGKSSRKRQDCSSSD--TEKYSMK--EDGCNSSDKRLKRIELRERRNLSSKRNTKEIQ 1112
K+ G+ SR+R+D SD TEK ++ EDG + R++ R+RR K KE
Sbjct: 1302 KIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDV 1361
Query: 1113 SGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIED 1172
+ +E + + + A+I + + S+ R+ +++ S E
Sbjct: 1362 EKAKKRRGRPPAEKLSPNPPKLTKQMNAII---DTVINYKDSSGRQLSEVFIQLPSRKEL 1418
Query: 1173 DDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP--- 1229
+ + D +KIK N +S GD L K V + + N
Sbjct: 1419 PEYYELIRKPVDFKKIKERIRNHKY-------RSLGD--LEKDVMLLCHNAQTFNLEGSQ 1469
Query: 1230 --ENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESD 1287
E+ I + + + + ++ +E+ S D+ EE ++ +++E + K ++N + D
Sbjct: 1470 IYEDSIVLQSVFKSARQKIAKEEE-SEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDD 1528
Query: 1288 SDSEESKKPRYRHRLLRHKLTVSDGESGEEK 1318
++ K + +R + K VSD +S EE+
Sbjct: 1529 KGRDKGKGKKRPNRG-KAKPVVSDFDSDEEQ 1558
Score = 35.4 bits (80), Expect = 0.70
Identities = 33/177 (18%), Positives = 74/177 (41%), Gaps = 21/177 (11%)
Query: 1242 IKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHR 1301
++A L +E+ +DE + + +EE + + D E+++ P+ + R
Sbjct: 1217 LQAILEHEEENEEEDEVPDDETLNQMIARR---EEEFDLFMRMDMDRRREDARNPKRKPR 1273
Query: 1302 LLRHKLTVS---DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSES 1358
L+ S ++ E+ T +E +++ GR R+ D D+ ++ +
Sbjct: 1274 LMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWL------- 1326
Query: 1359 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE 1415
R+ + LEE + + KK++RR V +D + E+ +++ E+
Sbjct: 1327 --------RAIEDGNLEEMEEEVRLKKRKRRRNVDKDPAKEDVEKAKKRRGRPPAEK 1375
Score = 35.4 bits (80), Expect = 0.70
Identities = 21/88 (23%), Positives = 41/88 (46%)
Query: 1333 RRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV 1392
R+K++ E+ + + E E+ ESE E + K + ++ R + KKR
Sbjct: 1485 RQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGK 1544
Query: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEE 1420
+ S+ S+ E++E E+ E ++E
Sbjct: 1545 AKPVVSDFDSDEEQDEREQSEGSGTDDE 1572
Score = 34.7 bits (78), Expect = 1.2
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 17/154 (11%)
Query: 1341 SEDSDFQESGVSEEVSESEDEQRPRTRSAKKAE----LEENQRSYKQKKKRRRIKVQEDS 1396
S+ +E+ ++E++ + + ++ R R K E + ++ + +K+ + K+Q+ S
Sbjct: 418 SKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLS 477
Query: 1397 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKIL-----KDDKL 1451
+ ++ E E+K+E E E+E E+++ +KK R++ D+ +
Sbjct: 478 KAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYV 537
Query: 1452 RTETQ--------NALKEEEERRKRIAERERERE 1477
T A KE+++RR+R + E E
Sbjct: 538 ANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENAE 571
Score = 33.9 bits (76), Expect = 2.0
Identities = 27/94 (28%), Positives = 36/94 (38%), Gaps = 17/94 (18%)
Query: 2368 QRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLI------------MNPSNYQQ 2415
Q+ ++ QQQ QQQQQQ QQ + P L+ PS Q+
Sbjct: 218 QQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQK 277
Query: 2416 IDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPGPS 2449
+ + P GG P A P + PGPS
Sbjct: 278 LPV-----PAPGGRPSPAPPAAAQPPAAAVPGPS 306
Score = 33.5 bits (75), Expect = 2.6
Identities = 20/97 (20%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 1329 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRR 1388
K ++ E+SED +EE E ++E+ + K +++ N++ K + K +
Sbjct: 1482 KSARQKIAKEEESEDES------NEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGK 1535
Query: 1389 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1425
K ++ + + +EE++E E+ E ++E
Sbjct: 1536 GKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE 1572
Score = 33.5 bits (75), Expect = 2.6
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 11/85 (12%)
Query: 631 ETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQN 690
E+N DEE +E+ + K+ + + KKD D D K K P +++ V +
Sbjct: 1497 ESNEEEEEEDEEESESEAKSVKVKIKLNKKD-----DKGRDKGKGKKRPNRGKAKPVVSD 1551
Query: 691 SDSDEMLAILKEVSRMSHSSSSDTD 715
DSDE E S S TD
Sbjct: 1552 FDSDE------EQDEREQSEGSGTD 1570
Score = 33.1 bits (74), Expect = 3.5
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 11/131 (8%)
Query: 1353 EEVSESEDE-QRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK 1411
EE +E EDE T + A EE + + RR +ED+ + + EE+E
Sbjct: 1224 EEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRR---REDARNPKRKPRLMEEDEL 1280
Query: 1412 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQ------NALKEEEER 1465
+++ E E E ++ K G+G ++ R + D L TE Q + EE E
Sbjct: 1281 PSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDAL-TEKQWLRAIEDGNLEEMEE 1339
Query: 1466 RKRIAERERER 1476
R+ +R+R R
Sbjct: 1340 EVRLKKRKRRR 1350
Score = 32.7 bits (73), Expect = 4.5
Identities = 72/404 (17%), Positives = 149/404 (36%), Gaps = 54/404 (13%)
Query: 955 KKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDK 1014
+KP I E++Y + ++ E E + P + E K+ ++ +
Sbjct: 332 QKPQGLDPVEILQEREYRLQARIAHRIQELENL---PGSLPPDLRTKATVELKALRLLNF 388
Query: 1015 TSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDT 1074
+ + E+ + T + +S K+SK RE + + L K + Q+
Sbjct: 389 QRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTL-REARMTEKLEKQQKIEQE-----R 442
Query: 1075 EKYSMKEDGCNSSDKRLKRIELRERRNLSSK--RNTKEIQSGSSSSDAEESSEDNKKKKQ 1132
++ ++ NS + K + R+++ K + +K + + ++++ E+ E + +K+
Sbjct: 443 KRRQKHQEYLNSILQHAKDFK-EYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKE 501
Query: 1133 RT------SSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQ 1186
R + ++ +KK L ++ + + ++ E + E +
Sbjct: 502 RMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRR 561
Query: 1187 KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANL 1246
+ K EN G+ AL D +P I + + ++ +
Sbjct: 562 RKKKAEENA----------EGGESALGP-----------DGEP---IDESSQMSDLPVKV 597
Query: 1247 SSDEDGSSDDEPEEGK-KRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRH 1305
+ E G PE K + E NPG E A + ESDSD EE + R
Sbjct: 598 THTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSR---- 653
Query: 1306 KLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQES 1349
+ EEK +EV ++ +++ +D D + S
Sbjct: 654 -------QETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYS 690
Score = 32.3 bits (72), Expect = 5.9
Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 11/116 (9%)
Query: 1391 KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK 1450
KV + + KS+S E + E EEE EEE+E +D++ + R++
Sbjct: 1197 KVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARRE--------- 1247
Query: 1451 LRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEE 1506
E ++ + +RR+ A + + +L E E+ +L +E+EE
Sbjct: 1248 --EEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEE 1301
Score = 32.3 bits (72), Expect = 5.9
Identities = 19/83 (22%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 1109 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVK------EKKRNSLRTSTKRKQADI 1162
KE +S S++ EE ++ + + + S K K + K +K + R + + + +
Sbjct: 1490 KEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPVV 1549
Query: 1163 TSSSSSDIEDDDQNSIGEGSSDE 1185
+ S + +D+ + S G G+ DE
Sbjct: 1550 SDFDSDEEQDEREQSEGSGTDDE 1572
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 116 bits (290), Expect = 3e-25
Identities = 266/1294 (20%), Positives = 482/1294 (37%), Gaps = 196/1294 (15%)
Query: 254 QQNKKKIKVDSEKSNKVYE-----HTSRF--SPKKTSSNCNGEEKKLDDSCSGSVTYSYS 306
Q+ K K+K +K K E + +F S ++ S+ +GE+ + DS S S
Sbjct: 448 QKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDR--DSLGSSGCLKGS 505
Query: 307 ALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSV------ 360
L+ +K +A+ SS+ Q + S TK + +K++
Sbjct: 506 PLV-----LKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWS 560
Query: 361 ----LADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKAR-KGEKPCALE 415
L+D + L E D +SE +++++ + +EH+ + E K+ A+
Sbjct: 561 EVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVP 620
Query: 416 KKDISKSEAKLSRKQVDSEHMHQN-----VPTEEQRTNKSTGGEHKKSDRKEEPQYEPAN 470
K D E K+ +K ++H H+N ++ KS E++ S +K + N
Sbjct: 621 KLD---KEGKVVKKH-KTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLEN 676
Query: 471 ---TSEDL-----DMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSS 522
T L D D + + E E + + S+ D + +
Sbjct: 677 DLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEK 736
Query: 523 VKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGL 582
+ N + K+ +K K+ + LY + + P K ++ +DK
Sbjct: 737 DRSNKAEKER--SLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKI------- 787
Query: 583 NPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEE 642
+ + E + + + L +E R S DE
Sbjct: 788 ------------SKEKEKIFKEDKEKLKKEKVYRED------------------SAFDEY 817
Query: 643 CNETV---KEKQKLSVPVRKKDKRNS--SDSAIDNPKPNKLPKSKQSETVDQNSDSDEML 697
CN+ E K S+ ++D+ S SDS+ D K S ++ D SDS L
Sbjct: 818 CNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDF-KGEDSWDSPVTDYRDMKSDSVAKL 876
Query: 698 AILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKG 757
IL+ V S D+ E +++ + K DK KRK T +K
Sbjct: 877 -ILETVKEDSKERRRDSRARE-KRDYREPFFRKKDRDYLDKNSEKRKEQT-------EKH 927
Query: 758 KSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKH 817
KS + K K++ +S + D + E + G A+ + K+ K
Sbjct: 928 KSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKD 987
Query: 818 SKKGMDNQG------HKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP 871
G +G H + ++ D ERK++ + E + DKD + + ++
Sbjct: 988 KSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQ 1047
Query: 872 KKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL 931
K ++ DK + +K + K K H K K K D + EK
Sbjct: 1048 KDKE-------FDKC---------FKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAF 1091
Query: 932 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP 991
S++ SE KK KKG E+ +D + E +S K+ E ++
Sbjct: 1092 PGIISEDFSE--KKDDKKGKEKSWYIADIFTD--ESEDDRDSCMGSGFKMGEASDLPR-T 1146
Query: 992 KGIKQIKNGTTD-GEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYG 1050
G+++ + G + +K DK ++ + + ++ +G + D+ DKK K
Sbjct: 1147 DGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRG-AADAGRDKKEKVFEKH 1205
Query: 1051 REKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKE 1110
+EKK TEKY ++D R ++ S ++ K
Sbjct: 1206 KEKK---------------DKESTEKYKDRKD----------------RASVDSTQDKKN 1234
Query: 1111 IQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDI 1170
Q ++ + ++ED K K + S K+ KE+K + + K + + +
Sbjct: 1235 KQKLPEKAEKKHAAEDKAKSKHKEKSDKEHS--KERKSSRSADAEKSLLEKLEEEALHEY 1292
Query: 1171 EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKS--VPVTVDDDDDDND 1228
+D + I E SSD + L F + GD+ +S +P + + +
Sbjct: 1293 REDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERHRH 1352
Query: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKN-QVNSESD 1287
+ K E K + ++ +D E G ++ Q E++ + +A N ++D
Sbjct: 1353 SSSSSKKSHDRERAKKEKAEKKE-KGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKAD 1411
Query: 1288 SDSEESKKPRYRHRLLRHKLTVSDGESGE--EKKTKPK--------EHKEVKGRNRRKVS 1337
+ E K + K S+ E + EK+ KP + K+ + ++R K
Sbjct: 1412 IEDELDKTIELFSTEKKDK-NDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWR 1470
Query: 1338 SEDSEDSDFQESGV-----SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKV 1392
E D G+ E + DEQ+P TR + + R K K +
Sbjct: 1471 DEKERHRDRHADGLLRHHRDELLRHHRDEQKPATR-----DKDSPPRVLKDKSR------ 1519
Query: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR-KILKD-DK 1450
++ + +E+ ++ E+E+ + + D+ SK PGK + R K+L D D
Sbjct: 1520 -DEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSKDPGKKDARPREKLLGDGDL 1578
Query: 1451 LRTETQNALKEE----EERRKRIAEREREREKLR 1480
+ T + L ++ EER KR ER ++ EKLR
Sbjct: 1579 MMTSFERMLSQKDLEIEERHKRHKERMKQMEKLR 1612
Score = 100 bits (249), Expect = 2e-20
Identities = 190/970 (19%), Positives = 369/970 (38%), Gaps = 126/970 (12%)
Query: 619 PRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDS-----AIDNP 673
P+ T P++ E + + +++ V +K L RK+ K NS S
Sbjct: 336 PQKATAPVKDEYEFD---EDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYT 392
Query: 674 KPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQA 733
K N + K S + ++ +E ++ S+ + I KT +
Sbjct: 393 KNNTIAPKKASHRILSDTSDEEDASVTVGTGEKLRLSA-----HTILPGSKTREPSNAKQ 447
Query: 734 GKD-DKGKRKRKSSTSGSD--FDTKKGKSAKSSIISKKKRQTQSESSNYDSE-------- 782
K+ +K K+KRK T G + F + K S S+ + + + S
Sbjct: 448 QKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGSPL 507
Query: 783 LEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGM-DNQGHKNLKTSQEGSS--D 839
+ K+ S + A+ T+ + + S ++H+K DN + E SS D
Sbjct: 508 VLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSD 567
Query: 840 DAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVR 899
+ E+ S+EG+ + ++ +R R +++AS S LS E + L+
Sbjct: 568 STRTRLTSESDYSSEGSSVE--SLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKE 625
Query: 900 KVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSD 959
K K+KH K + G I+++ K + E + +K K E ++
Sbjct: 626 GKVVKKHKTKHKH----KNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTE 681
Query: 960 FKKKVIKMEQQYESSSDGTEK--LPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSK 1017
K KV+K ++ + + K L E+E + K +K+IK+ D + ++ +D+++K
Sbjct: 682 NKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNK 741
Query: 1018 ------------KKDELSDYAEKSTGKGDSCDSSEDKKS--KNGAYGREKKRCKLLGKSS 1063
K+++L Y E+ K S +KK+ K +EK++ K
Sbjct: 742 AEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEK 801
Query: 1064 RKRQDCSSSDT--EKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAE 1121
K++ D+ ++Y K + D + + + R S ++ G S D+
Sbjct: 802 LKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSP 861
Query: 1122 ESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDD--DQNSIG 1179
+ D + K + +K VKE + R S R++ D + D D+NS
Sbjct: 862 VT--DYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNS-- 917
Query: 1180 EGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLL 1239
EQ K + LS + S + + + + D + A + L
Sbjct: 918 -EKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREEL 976
Query: 1240 EEIKANLS----SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1295
+E SD D EP E ++ +++ D+E K + E + K
Sbjct: 977 KECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKD 1036
Query: 1296 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG---VS 1352
+ L + + + +EKK ++HK+ G+++ + +S D +++ +S
Sbjct: 1037 KSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIIS 1096
Query: 1353 EEVSESEDEQRPRTRSAKKAEL----------------------------------EENQ 1378
E+ SE +D+++ + +S A++ EE +
Sbjct: 1097 EDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGR 1156
Query: 1379 RSY-------------------KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEE 1419
+Y K+ + RR+ + D+ + K E+ +EK+++E E+
Sbjct: 1157 EAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEK 1216
Query: 1420 EEEEEE-------EDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAER 1472
++ ++ +D+ + K P K KK K E + +E + R A+
Sbjct: 1217 YKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADA 1276
Query: 1473 ERE-REKLRE 1481
E+ EKL E
Sbjct: 1277 EKSLLEKLEE 1286
Score = 95.9 bits (237), Expect = 4e-19
Identities = 190/896 (21%), Positives = 341/896 (38%), Gaps = 124/896 (13%)
Query: 646 TVKEKQKL-SVPVRKKDKRNSSDSAI----DNPKPNKLPKSKQSETVDQNSDS------D 694
++ ++ KL S +D + SD AI D NKL K + + +
Sbjct: 647 SISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLE 706
Query: 695 EMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDT 754
E + K+ + ++ DI+ ++ + K ++ K +K + ++ S
Sbjct: 707 EKEWLFKDEKSLKRIKDTNKDIS------RSFREEKDRSNKAEKERSLKEKSPKEEKLRL 760
Query: 755 KKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDF--DSS 812
K + K S K R ++ E N +L+++ S K + K+++ K + DS+
Sbjct: 761 YKEERKKKS----KDRPSKLEKKN---DLKEDKISKEKEKIFKEDKEKLKKEKVYREDSA 813
Query: 813 EDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAE--GTVDKDTTIMELRDRL 870
DE +K NQ +N T S D +R + SS + G D+ + + RD
Sbjct: 814 FDEYCNK----NQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDM- 868
Query: 871 PKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKF 930
+D V KL + S E R+ + +EK + + KK +D L +EK
Sbjct: 869 --------KSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEK- 919
Query: 931 LKKDQSDE-------TSEDDKKQS----------------KKGTEEKKKPSDFKKKVIK- 966
+K+Q+++ SE DKK+ K+ + + KP + ++ +K
Sbjct: 920 -RKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKE 978
Query: 967 --MEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSD 1024
E ++ SDG F KG++ + EK+ K DK K+K +
Sbjct: 979 CGCESGFKDKSDGD-----------FGKGLEPWERHHPAREKEKKDGPDKERKEKTKPER 1027
Query: 1025 YAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGC 1084
Y EKS+ K S S +K K+ + + K K + K +D D E+ + + G
Sbjct: 1028 YKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKK---DTKEKHKDTHGKDKERKASLDQGK 1084
Query: 1085 NSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN--------KKKKQRTSS 1136
+K I + + KE + +ES +D K +
Sbjct: 1085 EKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLP 1144
Query: 1137 KKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIED--DDQNSIGEGSSDEQKIKPVTEN 1194
+ + KE+ R + + RK +D ++ D + G + K + V E
Sbjct: 1145 RTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEK 1204
Query: 1195 LVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSS 1254
+ D SV T D + PE K ++ K+ D
Sbjct: 1205 HKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEH 1264
Query: 1255 DDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGES 1314
E + + +++ +EEA ++ +S+ E + R LT S
Sbjct: 1265 SKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVS 1324
Query: 1315 GEEKK--TKPKEH----KEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1368
E KP+E +++K + R + SS S+ +S D +R +
Sbjct: 1325 FTEPPGDDKPRESACLPEKLKEKERHRHSSSSSK--------------KSHDRERAKK-- 1368
Query: 1369 AKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE---EEE 1425
+KAE +E YK+ R+ E E + + + E+E ++ E E+
Sbjct: 1369 -EKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEK 1427
Query: 1426 EDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1481
+D+ND + P K KI K LK + N LKE+++R K + E+E+ R+
Sbjct: 1428 KDKNDSEREPSK---KIEKELKP--YGSSAINILKEKKKREKHREKWRDEKERHRD 1478
Score = 81.6 bits (200), Expect = 8e-15
Identities = 173/848 (20%), Positives = 314/848 (37%), Gaps = 137/848 (16%)
Query: 744 KSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRI 803
+SST S+ + + SS+ + +N DSE EK +K +K + +
Sbjct: 294 ESSTESSEEEDAPSFAPSSSV----------DGNNTDSEFEKGLKHKAKNPEPQKATAPV 343
Query: 804 PNTKDFDSSEDEKHSKKGMDNQG--HKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDT 861
+ +FD +DE+ +D++ K+ + + +S + K E ++++ K
Sbjct: 344 KDEYEFD-EDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIAPKKA 402
Query: 862 TIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAE-TKEKSKHLKTKTCKKVQ 920
+ L D ++ AS + +KL + + T L K E + K + K K KK +
Sbjct: 403 SHRILSD-TSDEEDASVTVGTGEKL--RLSAHTILPGSKTREPSNAKQQKEKNKVKKKRK 459
Query: 921 DGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEK----------------KKPSDFKKKV 964
+F K+ +SE + + S+ G +++ K PS F
Sbjct: 460 KETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSLS 519
Query: 965 IKMEQQYESSSD--------------------GTEKLPEREEICHFPKGIKQIKNGTTDG 1004
+ SS+ T P E+ + +D
Sbjct: 520 ASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDY 579
Query: 1005 EKKSKKIRD-KTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSS 1063
+ + K +K+ E A S K S+E K G+ K+ K K
Sbjct: 580 SSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHK 639
Query: 1064 RKRQ-DCSSSDTEKYSM----KEDGCNSSDK----------------------------R 1090
K + CS S K ED SDK +
Sbjct: 640 NKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEK 699
Query: 1091 LKRIELRER----RNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEK 1146
L +++L E+ ++ S + K+ S S EE NK +K+R+ +K KE+
Sbjct: 700 LSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSP---KEE 756
Query: 1147 KRNSLRTSTKRKQADITS--SSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFC 1204
K + K+K D S +D+++D + E E K K E +
Sbjct: 757 KLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYRE------ 810
Query: 1205 QSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSD-EDGSSDDEPEEGKK 1263
S+ DE +K+ + EN K L ++ + SD D S D + E+
Sbjct: 811 DSAFDEYCNKNQFL-----------ENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWD 859
Query: 1264 RTGKQNEENPGDEEAK------NQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEE 1317
+ D AK + + E DS +K YR R K ++ E+
Sbjct: 860 SPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEK 919
Query: 1318 KKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSE----EVSESEDEQRPRTRSAKKAE 1373
+K + ++HK V G +S +D + + E+G E + + R + A + E
Sbjct: 920 RKEQTEKHKSVPG----YLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREE 975
Query: 1374 LEE--NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431
L+E + +K K K E + + +E+++ ++E +E+ + E +E +D
Sbjct: 976 LKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDK 1035
Query: 1432 SKSPGKGRKKIRKILKDDKLRTETQNALK-------EEEERRKRIAEREREREKLREVIE 1484
KS +K +K + DK E ++ + +++ER+ + + + ++EK I
Sbjct: 1036 DKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGII 1095
Query: 1485 IEDASPTK 1492
ED S K
Sbjct: 1096 SEDFSEKK 1103
Score = 77.8 bits (190), Expect = 1e-13
Identities = 121/544 (22%), Positives = 221/544 (40%), Gaps = 74/544 (13%)
Query: 971 YESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDK-------TSKKKDELS 1023
Y SS + + + E E+ F N T +K K + K T+ KDE
Sbjct: 289 YTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKDE-- 346
Query: 1024 DYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDT--EKYSMKE 1081
Y + D +DK Y +E K + + + + ++T K +
Sbjct: 347 -YEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIAPKKASHR 405
Query: 1082 DGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSS---SDAEESSEDNKKKKQRTSSKK 1138
++SD+ + + L +T I GS + S+A++ E NK KK+R K
Sbjct: 406 ILSDTSDEEDASVTVGTGEKLRLSAHT--ILPGSKTREPSNAKQQKEKNKVKKKRKKETK 463
Query: 1139 KAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVT---ENL 1195
+ K+ + +S + S SS+ +DD++S+G SS K P+ +L
Sbjct: 464 GREVRFGKRSDKFCSSE-------SESESSESGEDDRDSLG--SSGCLKGSPLVLKDPSL 514
Query: 1196 VLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN--RIAK------KMLLEEIKANLS 1247
S S G A K P D +N I+ L + + L+
Sbjct: 515 FSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLT 574
Query: 1248 SDEDGSSDDEP----------EEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPR 1297
S+ D SS+ +E +KR +++P A+ V + D + + KK +
Sbjct: 575 SESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAV-PKLDKEGKVVKKHK 633
Query: 1298 YRHRLLRHKLTVSDGESGEEKKTKPK----EHKEVKGRNRRKVSSEDSEDSDFQESGVSE 1353
+H+ HK G+ ++ K K E+++ K ++ + + E+ ++ + +
Sbjct: 634 TKHK---HK-NKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKH 689
Query: 1354 EVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIK---------VQEDSSSENKSNS 1404
+ + E++ K +LEE + +K +K +RIK +E+ NK+
Sbjct: 690 DRDHFKKEEK-----LSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEK 744
Query: 1405 EEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEE 1464
E +EK +EE+ +EE + ++ D P K KK LK+DK+ E + KE++E
Sbjct: 745 ERSLKEKSPKEEKLRLYKEERKKKSKD--RPSKLEKK--NDLKEDKISKEKEKIFKEDKE 800
Query: 1465 RRKR 1468
+ K+
Sbjct: 801 KLKK 804
Score = 67.4 bits (163), Expect = 2e-10
Identities = 135/574 (23%), Positives = 233/574 (40%), Gaps = 77/574 (13%)
Query: 887 SGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQ 946
S +E S S E S T + + GL A+ + Q D+ +
Sbjct: 291 SSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKN--PEPQKATAPVKDEYE 348
Query: 947 SKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK 1006
+ E+ + P K ++K + + E+ S+ +P+ E + KN T +K
Sbjct: 349 FDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSY-------TKNNTIAPKK 401
Query: 1007 KSKKIRDKTSKKKD-----------ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKR 1055
S +I TS ++D LS + K +++ +K KN + KK
Sbjct: 402 ASHRILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKEKNKVKKKRKKE 461
Query: 1056 CKLLGKSSRKRQD--CSS-SDTEKYSMKEDGCNS--SDKRLKR--IELRERRNLSSKRNT 1108
K KR D CSS S++E ED +S S LK + L++ SS +
Sbjct: 462 TKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSAS 521
Query: 1109 KEIQSGSSSSDAEESSE-DNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSS 1167
GSS++ + S D K RT + K + +SL ST+ + +TS S
Sbjct: 522 STSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTR---LTSES- 577
Query: 1168 SDIEDDDQNSIGEGSSDEQKIKPVTEN------LVLSSHTGFCQSSGDEALSKSVPVTVD 1221
D +S EGSS E +KPV + LS SS + A+ K
Sbjct: 578 ------DYSS--EGSSVES-LKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKL------ 622
Query: 1222 DDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQ 1281
D E ++ KK + K + E G E K + E++ +++
Sbjct: 623 ------DKEGKVVKK---HKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSK--QKSDKA 671
Query: 1282 VNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPK-EHKEVKGRNRRKVSSED 1340
+ E+D +E K +L+H D EEK +K K E KE ++ + +
Sbjct: 672 ILLENDLSTENKLK------VLKHD---RDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIK 722
Query: 1341 SEDSDFQESGVSEE--VSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSS- 1397
+ D S E+ +++E E+ + +S K+ +L + K+K K R K+++ +
Sbjct: 723 DTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDL 782
Query: 1398 SENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431
E+K + E+E+ KE++E+ ++E+ E+ D+
Sbjct: 783 KEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDE 816
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 114 bits (285), Expect = 1e-24
Identities = 87/275 (31%), Positives = 136/275 (49%), Gaps = 40/275 (14%)
Query: 1975 VLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYK 2034
++ SGK++LL ++L+ +E G +VL+FSQ LDL+EDFLE YK
Sbjct: 1045 LIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHEG------------YK 1092
Query: 2035 GEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRV 2094
Y R+DG T R++ + FN + F++ST+AG LGINL A+ V
Sbjct: 1093 ----------YERIDGGITGNMRQEAIDRFN-APGAQQFCFLLSTRAGGLGINLATADTV 1141
Query: 2095 IIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQ 2154
II+D+ WNP DIQ+ R +R GQ K V +YRF+ + ++E++I K L+ VV
Sbjct: 1142 IIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHLVVRP 1201
Query: 2155 QQVERHFTMN--ELTELYTFEPDLL-----DDPNSEKKKKRDTPMLPKDTILAELL---- 2203
+ +M+ EL ++ F + L D + K+ D+ ++ D E L
Sbjct: 1202 GLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDRN 1261
Query: 2204 --QIHKEHIVGYHEHDSLLDHKE----EEELTEEE 2232
+ + G +E+ S + EEE+ EEE
Sbjct: 1262 QDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEE 1296
Score = 95.9 bits (237), Expect = 4e-19
Identities = 99/385 (25%), Positives = 165/385 (42%), Gaps = 51/385 (13%)
Query: 1480 REVIEIEDASPTKCPITTKL-VLDEDEETK--EPLVQVHRNMVI------KLKPHQVDGV 1530
RE++ E+ P K KL L+ ET +P V+ R L P+Q++G+
Sbjct: 675 RELMRGEEGRPGKKLKKVKLRKLERPPETPTVDPTVKYERQPEYLDATGGTLHPYQMEGL 734
Query: 1531 QFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPL 1590
++ + + G+ ILA MGLGKT+Q FL++ L + LV PL
Sbjct: 735 NWL---------RFSWAQGTDTILADEMGLGKTVQTAVFLYS-LYKEGHSKGPFLVSAPL 784
Query: 1591 NTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRN 1650
+T +NW EFE W + + + + R E S+ ED + G +
Sbjct: 785 STIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSF------EDNAIR--GGKKASR 836
Query: 1651 LAQGRNVKSRKLKEIFNKALVDPGP------DFVVCDEGHILKNEASAVSKAMNSIRSRR 1704
+ + +VK L + +D ++ DE H LKN S + +N +
Sbjct: 837 MKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQH 896
Query: 1705 RIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKK 1764
+++LTGTPLQNNL E ++NF+ +++ F F + + Q +KK
Sbjct: 897 KLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQ-----------IKK 945
Query: 1765 RAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSE 1824
L++ML + R+ + K +P K E ++ V ++ +Q K Y+Y L N
Sbjct: 946 ----LHDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARG 1001
Query: 1825 GGRGKAGAKLFQDFQMLSRIWTHPW 1849
GG + + D L + HP+
Sbjct: 1002 GGNQVSLLNVVMD---LKKCCNHPY 1023
Score = 52.0 bits (123), Expect = 7e-06
Identities = 41/141 (29%), Positives = 64/141 (45%), Gaps = 33/141 (23%)
Query: 1348 ESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQ-EDSSSENKSNSEE 1406
E E++SE+E + + + KK + +S +QKK+R + Q DSS E EE
Sbjct: 36 EEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEE 95
Query: 1407 EEE------------------------EKEEEEEEEEEEEEEEEDENDDSKSPGK----- 1437
EEE +KE++ + + +EEEEEED++DDSK P
Sbjct: 96 EEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLL 155
Query: 1438 ---GRKKIRKILKDDKLRTET 1455
G + I + ++ RT T
Sbjct: 156 EDWGMEDIDHVFSEEDYRTLT 176
Score = 42.0 bits (97), Expect = 0.007
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 19/124 (15%)
Query: 932 KKDQSDETSEDDKKQSKKGTEEKKKPSD---------FKKKVIKMEQQYESSSDGTEKLP 982
++D ++ SE + + KK ++ KKP D K++++ Q +SS +G E +
Sbjct: 36 EEDPEEDLSETETPKLKK-KKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVE 94
Query: 983 EREEICHFPKGIKQIKNGT--TDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSE 1040
E EE+ ++ G+ T G+KK KK+ K K+K S E+ + D DS E
Sbjct: 95 EEEEVA-----LRSDSEGSDYTPGKKKKKKLGPK--KEKKSKSKRKEEEEEEDDDDDSKE 147
Query: 1041 DKKS 1044
K S
Sbjct: 148 PKSS 151
Score = 40.4 bits (93), Expect = 0.022
Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 7/61 (11%)
Query: 170 DISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYCYI 229
D+ + D E CR C +GG L+CCD C +++ C+ N E+ N +W C
Sbjct: 440 DLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCL--NPPLPEI-----PNGEWLCPR 492
Query: 230 C 230
C
Sbjct: 493 C 493
Score = 38.1 bits (87), Expect = 0.11
Identities = 66/337 (19%), Positives = 133/337 (39%), Gaps = 40/337 (11%)
Query: 1067 QDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSED 1126
+D S ++T K K+ D ++ + + +++ + R Q G SS + E E+
Sbjct: 41 EDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCR-----QLGDSSGEGPEFVEE 95
Query: 1127 NKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQ 1186
++ R+ S+ +KK+ L ++K + +DDD + + S+
Sbjct: 96 EEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLL 155
Query: 1187 KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANL 1246
+ + + + S + + +A S+ V + +P+ ++K M++ L
Sbjct: 156 EDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLI----AAKNPKIAVSKMMMV------L 205
Query: 1247 SSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSES-------------DSDSEES 1293
+ S + P +G ++ V + + ++E
Sbjct: 206 GAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVAPPPPPVEVPIRKAKTKEG 265
Query: 1294 KKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHK-EVKGRNRRKVSSEDSE---DSDFQES 1349
K P R R + V D + + KK P + K G R++ SSED + +SDF ++
Sbjct: 266 KGPNAR-RKPKGSPRVPDAKKPKPKKVAPLKIKLGGFGSKRKRSSSEDDDLDVESDFDDA 324
Query: 1350 GVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKK 1386
++ S S+ +RS KK R+ K+KKK
Sbjct: 325 SIN-SYSVSDGSTSRSSRSRKKL------RTTKKKKK 354
Score = 37.4 bits (85), Expect = 0.18
Identities = 34/193 (17%), Positives = 84/193 (43%), Gaps = 35/193 (18%)
Query: 1261 GKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLT---VSDGESGEE 1317
G + G+ + D++A ++ + ++E+++ L K+ V + E GEE
Sbjct: 1236 GDNKEGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEE 1295
Query: 1318 KKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEEN 1377
++ + R + E+S D D+ E + + +++
Sbjct: 1296 EEVE-----------REIIKQEESVDPDYWEKLLRHHYEQQQEDLA-------------- 1330
Query: 1378 QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGK 1437
+ K +RI+ Q + + ++ + + ++++ + + + EE +ED ++ S++P
Sbjct: 1331 ----RNLGKGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDEDFDERSEAP-- 1384
Query: 1438 GRKKIRKILKDDK 1450
R+ RK L++DK
Sbjct: 1385 -RRPSRKGLRNDK 1396
Score = 36.6 bits (83), Expect = 0.31
Identities = 41/171 (23%), Positives = 77/171 (45%), Gaps = 11/171 (6%)
Query: 1311 DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAK 1370
DG EE K E + ++G K ++ ++ Q + E + E +
Sbjct: 1562 DGIKIEENSLK--EEESIEGEKEVKSTAPETAIECTQAPAPASEDEKVVVEPPEGEEKVE 1619
Query: 1371 KAELEENQRSYKQKKKRRRI---KVQEDSSSENKSNSEEEEEEKEEEEEEEE---EEEEE 1424
KAE++E + + + KV+E S+ + E++EEK+EEEE++E + E
Sbjct: 1620 KAEVKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVMLQNGET 1679
Query: 1425 EEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERE 1475
+D ND+ + ++ + I D TE ++L + EER + ++ E
Sbjct: 1680 PKDLNDEKQKKNIKQRFMFNIA--DGGFTEL-HSLWQNEERAATVTKKTYE 1727
Score = 35.8 bits (81), Expect = 0.53
Identities = 33/136 (24%), Positives = 56/136 (41%), Gaps = 23/136 (16%)
Query: 634 PVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETV------ 687
P ++E+ E + E + + +KK K+ P+ K+PKSK+ +
Sbjct: 30 PPHPENEEDPEEDLSETETPKLKKKKKPKK---------PRDPKIPKSKRQKKERMLLCR 80
Query: 688 ---DQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRK 744
D + + E + +EV+ S S SD + K L + K K KRK +
Sbjct: 81 QLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGK-----KKKKKLGPKKEKKSKSKRKEE 135
Query: 745 SSTSGSDFDTKKGKSA 760
D D+K+ KS+
Sbjct: 136 EEEEDDDDDSKEPKSS 151
Score = 34.7 bits (78), Expect = 1.2
Identities = 33/142 (23%), Positives = 55/142 (38%), Gaps = 11/142 (7%)
Query: 1212 LSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEE 1271
L P + +++D D + L N E+ S+ E + KK+ +
Sbjct: 5 LGSPSPCSAGSEEEDMDA---LLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPR 61
Query: 1272 NPGDEEAKNQVNSE-------SDSDSEESKKPRYRHRL-LRHKLTVSDGESGEEKKTKPK 1323
+P ++K Q DS E + + LR SD G++KK K
Sbjct: 62 DPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLG 121
Query: 1324 EHKEVKGRNRRKVSSEDSEDSD 1345
KE K +++RK E+ +D D
Sbjct: 122 PKKEKKSKSKRKEEEEEEDDDD 143
>gi|38708321 INO80 complex homolog 1 [Homo sapiens]
Length = 1556
Score = 114 bits (284), Expect = 2e-24
Identities = 85/338 (25%), Positives = 156/338 (46%), Gaps = 47/338 (13%)
Query: 1975 VLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYK 2034
++ SGK+ L +L + G +VL++SQ +DL+E+++ +Y
Sbjct: 1096 LITDSGKLYALDVLLTRLKSQGHRVLIYSQMTRMIDLLEEYM---------------VY- 1139
Query: 2035 GEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRV 2094
R Y RLDGS+ R+ +F + ++ +F++ST+AG LGINL AA+ V
Sbjct: 1140 ------RKHTYMRLDGSSKISERRDMVADFQNRNDIF--VFLLSTRAGGLGINLTAADTV 1191
Query: 2095 IIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQ 2154
I +D+ WNP+ D Q++ R +R GQTK V VYR + +GT+E++I R K + V+
Sbjct: 1192 IFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMVISG 1251
Query: 2155 QQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHKEHIVGYH 2214
F+PD L K K +L D L + L++ +E
Sbjct: 1252 G---------------NFKPDTL-------KPKEVVSLLLDDEELEKKLRLRQEEKRQQE 1289
Query: 2215 EHDSLLDHK-EEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPF 2273
E + + + K + E+ E+++K + + K+G+ + + +S + +I
Sbjct: 1290 ETNRVKERKRKREKYAEKKKKEDELDGKRRKEGVNLVIPFVPSADNSNLSADGDDSFISV 1349
Query: 2274 NLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP 2311
+ S S + ++ G + E+++ + + P
Sbjct: 1350 DSAMPSPFSEISISSELHTGSIPLDESSSDMLVIVDDP 1387
Score = 72.4 bits (176), Expect = 5e-12
Identities = 161/803 (20%), Positives = 307/803 (38%), Gaps = 142/803 (17%)
Query: 1051 REKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN-TK 1109
+E+ LLG++S SS YS+ +G S+ + + L L R K
Sbjct: 73 KEEPPNSLLGETSGAG---SSGMLNTYSL--NGVLQSESKCDKGNLYNFSKLKKSRKWLK 127
Query: 1110 EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSD 1169
I SS+A+ SED+ +++ S +E+ N LR +K S +
Sbjct: 128 SILLSDESSEADSQSEDDDEEELNLS--------REELHNMLRLHKYKKLHQNKYSKDKE 179
Query: 1170 IEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP 1229
++ S G +LS++ F + K
Sbjct: 180 LQQYQYYSAG----------------LLSTYDPFYEQQRHLLGPKKKKFK---------E 214
Query: 1230 ENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRT---GKQNEENPGDEEAKNQVNSES 1286
E ++ K L+++K DE+ SS++ P +T K + + P K ++ E
Sbjct: 215 EKKLKAK--LKKVKKKRRRDEELSSEESPRRHHHQTKVFAKFSHDAPPPGTKKKHLSIE- 271
Query: 1287 DSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKE-VKGRNRRKVSSEDSEDSD 1345
+ R K+ +S KK PK +K+ RN +S
Sbjct: 272 ------------QLNARRRKVWLSI-----VKKELPKANKQKASARNLFLTNSRKLAHQC 314
Query: 1346 FQE-SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1404
+E + + ++ E PR R K E+ + Y++ +K R + ++++ + K +
Sbjct: 315 MKEVRRAALQAQKNCKETLPRARRLTK-EMLLYWKKYEKVEKEHRKRAEKEALEQRKLDE 373
Query: 1405 EEEEEEKEEEEEE----EEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQ---- 1456
E E ++++ + + E D G + +RK L+D + +
Sbjct: 374 EMREAKRQQRKLNFLITQTELYAHFMSRKRDMGHDGIQEEILRK-LEDSSTQRQIDIGGG 432
Query: 1457 ---NALKEEEERRKRIAEREREREKLREVIEI------EDASPTKCPIT-----TKLVLD 1502
N +E+ + A+ + E + + EDA ++ +
Sbjct: 433 VVVNITQEDYDSNHFKAQALKNAENAYHIHQARTRSFDEDAKESRAAALRAANKSGTGFG 492
Query: 1503 EDEETKEPLVQVHRNMVI------KLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAH 1556
E P ++ ++ KLK +Q+ G+ ++ + G ILA
Sbjct: 493 ESYSLANPSIRAGEDIPQPTIFNGKLKGYQLKGMNWLANLY---------EQGINGILAD 543
Query: 1557 CMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVS 1616
MGLGKT+Q ++ L + + + + L++ P +T NW EF ++ K
Sbjct: 544 EMGLGKTVQSIALLAHLAERENI-WGPFLIISPASTLNNWHQEFTRFVPKFK-------- 594
Query: 1617 ELATVKRPQERSYMLQRWQEDG--------GVMIIGYEMY-RNLAQGRNVKSRKLKEIFN 1667
L P +R + + W + V+I Y++ +++ + VK +
Sbjct: 595 VLPYWGNPHDRKVIRRFWSQKTLYTQDAPFHVVITSYQLVVQDVKYFQRVKWQ------- 647
Query: 1668 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI 1727
++V DE LK+ +S K + + R R++LTGTP+QN + E +++FI
Sbjct: 648 ---------YMVLDEAQALKSSSSVRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFI 698
Query: 1728 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK 1787
L S +EF F I++ + + +D + + L+ +L + R+ +
Sbjct: 699 MPTLFDSHEEFNEWFSKDIES-HAENKSAIDENQLSR----LHMILKPFMLRRIKKDVEN 753
Query: 1788 FLPPKHEYVLAVRMTSIQCKLYQ 1810
L K E ++ ++TS Q LYQ
Sbjct: 754 ELSDKIEILMYCQLTSRQKLLYQ 776
Score = 43.5 bits (101), Expect = 0.003
Identities = 79/351 (22%), Positives = 131/351 (37%), Gaps = 32/351 (9%)
Query: 1151 LRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDE 1210
LR ++ +I+S S D DD + + ++K N +L +G S
Sbjct: 35 LRQTSAIFNRNISSDDSEDGLDDSNPLLPQSGDPLIQVKEEPPNSLLGETSGAGSSGMLN 94
Query: 1211 ALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE 1270
S + + + D + N K + +K+ L SDE +D + E+ + E
Sbjct: 95 TYSLNGVLQSESKCDKGNLYNFSKLKKSRKWLKSILLSDESSEADSQSEDDD-----EEE 149
Query: 1271 ENPGDEEAKNQVN---------SESDSDSEESKKPRYRHRLL----------RHKLTVSD 1311
N EE N + ++ D E + Y LL RH L
Sbjct: 150 LNLSREELHNMLRLHKYKKLHQNKYSKDKELQQYQYYSAGLLSTYDPFYEQQRHLLGPKK 209
Query: 1312 GESGEEKKTKPKEHKEVKGRNR-RKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAK 1370
+ EEKK K K K K R R ++SSE+S ++ V + S D P T K
Sbjct: 210 KKFKEEKKLKAKLKKVKKKRRRDEELSSEESPRRHHHQTKVFAKF--SHDAPPPGT---K 264
Query: 1371 KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430
K L Q + +++K I +E + + S + + +E
Sbjct: 265 KKHLSIEQLNARRRKVWLSIVKKELPKANKQKASARNLFLTNSRKLAHQCMKEVRRAALQ 324
Query: 1431 DSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1481
K+ + + R++ K+ L + K E+E RKR + E+ KL E
Sbjct: 325 AQKNCKETLPRARRLTKEMLLYWKKYE--KVEKEHRKRAEKEALEQRKLDE 373
Score = 37.0 bits (84), Expect = 0.24
Identities = 67/287 (23%), Positives = 112/287 (39%), Gaps = 44/287 (15%)
Query: 606 VSLLLEESDLRRSPRVKTTPLRRPTETNPV-------------TSNSDEECNETVKEKQK 652
VSLLL++ +L + R++ R+ ETN V DE + KE
Sbjct: 1265 VSLLLDDEELEKKLRLRQEEKRQQEETNRVKERKRKREKYAEKKKKEDELDGKRRKEGVN 1324
Query: 653 LSVP-VRKKDKRN----------SSDSAIDNP-KPNKLPKSKQSETVDQNSDSDEMLAIL 700
L +P V D N S DSA+ +P + + ++ + S +ML I+
Sbjct: 1325 LVIPFVPSADNSNLSADGDDSFISVDSAMPSPFSEISISSELHTGSIPLDESSSDMLVIV 1384
Query: 701 KE------VSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDF-D 753
+ SR ++S +S T N ++ ++ AG+ + + + SGS
Sbjct: 1385 DDPASSAPQSRATNSPASITGSVSDTVNGISIQEMPA-AGRGHSARSRGRPKGSGSTAKG 1443
Query: 754 TKKGKSAKS------SIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTK 807
KG+S KS ++ K + ++ Y + K +S +T+ R
Sbjct: 1444 AGKGRSRKSTAGSAAAMAGAKAGAAAASAAAYAAYGYNVSKGISASSPLQTSLVRPAGLA 1503
Query: 808 DFD----SSEDEKHSKKGMDNQGH-KNLKTSQEGSSDDAERKQERET 849
DF SS KG + G+ KNL + + D RKQ + T
Sbjct: 1504 DFGPSSASSPLSSPLSKGNNVPGNPKNLHMTSSLAPDSLVRKQGKGT 1550
Score = 32.3 bits (72), Expect = 5.9
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
Query: 1409 EEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRK- 1467
EE+ + +E+ E + + K K++ +L DD+ E + L++EE+R++
Sbjct: 1231 EERILQRAKEKSEIQRMVISGGNFKPDTLKPKEVVSLLLDDE-ELEKKLRLRQEEKRQQE 1289
Query: 1468 ---RIAEREREREKLREVIEIED 1487
R+ ER+R+REK E + ED
Sbjct: 1290 ETNRVKERKRKREKYAEKKKKED 1312
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 113 bits (283), Expect = 2e-24
Identities = 76/255 (29%), Positives = 127/255 (49%), Gaps = 49/255 (19%)
Query: 1974 EVLEH----SGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDK 2029
E L+H SGK++LL ++L E G++VL+FSQ + LD++ ++L+
Sbjct: 778 EALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKY----------- 826
Query: 2030 PLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLV 2089
R + RLDGS + RK+ + FN E + F++ST+AG LGINL
Sbjct: 827 -----------RQFPFQRLDGSIKGELRKQALDHFNAEGS-EDFCFLLSTRAGGLGINLA 874
Query: 2090 AANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSF 2149
+A+ V+IFD+ WNP D+Q+ R +R GQ K V +YR + +G++E+ I +R K L
Sbjct: 875 SADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDH 934
Query: 2150 RVVDQQQV--------------ERHFTMNELTELYTF-EPDLLDDPNSEKKKKRDTPMLP 2194
V+ + F EL+ + F +L +P E+++ P
Sbjct: 935 LVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQE-------P 987
Query: 2195 KDTILAELLQIHKEH 2209
++ + E+L+ + H
Sbjct: 988 QEMDIDEILKRAETH 1002
Score = 90.9 bits (224), Expect = 1e-17
Identities = 73/295 (24%), Positives = 140/295 (47%), Gaps = 44/295 (14%)
Query: 1520 IKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKL 1579
++L+ +Q++G+ ++ C+ G+ CILA MGLGKT+Q +SFL+ + +L
Sbjct: 479 LELRDYQLNGLNWLAHSWCK---------GNSCILADEMGLGKTIQTISFLNYLFHEHQL 529
Query: 1580 DFSTALVVCPLNTALNWMNEFEKWQEGLKDDEKL-EVSELATVKRPQERSYMLQRWQEDG 1638
+ L+V PL+T +W E + W + L +++ ++ + + +R + +
Sbjct: 530 -YGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFN- 587
Query: 1639 GVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMN 1698
+++ YE+ +K + N A F+ DE H LKN+ S + K +
Sbjct: 588 -ILLTTYEIL--------LKDKAFLGGLNWA-------FIGVDEAHRLKNDDSLLYKTLI 631
Query: 1699 SIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVD 1758
+S R+++TGTPLQN+L E +++FI S ++F + G +
Sbjct: 632 DFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYAS------ 685
Query: 1759 VRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYL 1813
L++ L + R+ + K LP K E +L + M+++Q + Y++ L
Sbjct: 686 ----------LHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWIL 730
Score = 58.2 bits (139), Expect = 1e-07
Identities = 60/270 (22%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 1163 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1222
+S SS +DD ++ G GS SS QS ++ S S + +
Sbjct: 13 SSGESSQSDDDSGSASGSGSGSSSGS---------SSDGSSSQSGSSDSDSGSESGSQSE 63
Query: 1223 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1282
+ D EN++ K + S + KK+ +Q ++ +A +
Sbjct: 64 SESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQ---HQASSNS 120
Query: 1283 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHK-EVKGRNRRKVSSEDS 1341
SE DS S E SD S E K+ K K+ ++ G S DS
Sbjct: 121 GSEEDSSSSED----------------SDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDS 164
Query: 1342 EDSDFQE-SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSEN 1400
E + +E S E S+ E + + ++R + +N + +KKR+ +ED E+
Sbjct: 165 ESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEED 224
Query: 1401 KSNSEEEEEEKEEEEEEEEEEEEEEEDEND 1430
N + + +E+EE + D +D
Sbjct: 225 YDNDKRSSRRQATVNVSYKEDEEMKTDSDD 254
Score = 57.8 bits (138), Expect = 1e-07
Identities = 54/261 (20%), Positives = 115/261 (44%), Gaps = 49/261 (18%)
Query: 1240 EEIKANLSSDEDGSSDDE----------PEEGKKRTGKQNEENPGDEEAKNQVNSESDSD 1289
+E SS E SDD+ G G ++ D ++ ++ S+S+S+
Sbjct: 6 DEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESE 65
Query: 1290 SEESKKPRYRHR---------------LLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR 1334
S+ S++ + + + +L + + + ++++ + + G
Sbjct: 66 SDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEED 125
Query: 1335 KVSSEDSEDS------------DFQESG---VSEEVSESEDEQRPRTRSAKKAELEENQR 1379
SSEDS+DS D+Q SG S+ S+SE E+ +K+ +E +
Sbjct: 126 SSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEE-----EREKSSCDETES 180
Query: 1380 SYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGR 1439
Y+ K K + K Q S S+ N ++ +K+ + + EE+++EE+ +ND S +
Sbjct: 181 DYEPKNKVKSRKPQNRSKSK---NGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQAT 237
Query: 1440 KKIRKILKDDKLRTETQNALK 1460
+ +D++++T++ + L+
Sbjct: 238 VNV-SYKEDEEMKTDSDDLLE 257
Score = 47.0 bits (110), Expect = 2e-04
Identities = 60/317 (18%), Positives = 126/317 (39%), Gaps = 69/317 (21%)
Query: 1251 DGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSE-SDSDSEESKKPRYRHRLLRHKLTV 1309
+G SD+E Q++++ G +S S SD S+
Sbjct: 2 NGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGS------------ 49
Query: 1310 SDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSA 1369
SD +SG E ++ + + N+ + + ++F +S S
Sbjct: 50 SDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPS----------------- 92
Query: 1370 KKAELEENQRSYKQKKKRRRIKVQ------------EDSSSENKSNSEEEEEEKEEEEE- 1416
+ QRS KK++++ + Q + SSSE+ +S E + K+ ++E
Sbjct: 93 ----ILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDED 148
Query: 1417 --------------EEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE 1462
+ E EEE E+ D+++S + + K++ + + R++++N K
Sbjct: 149 WQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKS--RKPQNRSKSKNGKKIL 206
Query: 1463 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETK---EPLVQVHRNMV 1519
+++++I E + + E D ++ T + EDEE K + L++V V
Sbjct: 207 GQKKRQIDSSEEDDD---EEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGEDV 263
Query: 1520 IKLKPHQVDGVQFMWDC 1536
+ + + + ++ DC
Sbjct: 264 PQPEEEEFETIERFMDC 280
Score = 45.8 bits (107), Expect = 5e-04
Identities = 81/371 (21%), Positives = 132/371 (35%), Gaps = 100/371 (26%)
Query: 1068 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN 1127
+ S SD + S G SS S + QSGSS SD+ S
Sbjct: 16 ESSQSDDDSGSASGSGSGSSS--------------GSSSDGSSSQSGSSDSDSGSESGSQ 61
Query: 1128 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK 1187
+ + TS + K V K K + A+ SS S + + + +Q+
Sbjct: 62 SESESDTSRENK-VQAKPPKVDG---------AEFWKSSPSILAVQRSAILKKQQQQQQQ 111
Query: 1188 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS 1247
H S +E S S +D DD+ E + K + +
Sbjct: 112 ----------QQHQASSNSGSEEDSSSS------EDSDDSSSEVKRKKHKDEDWQMSGSG 155
Query: 1248 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL 1307
S SD E EE ++++ +E D E KN+V +S+KP
Sbjct: 156 SPSQSGSDSESEEEREKS--SCDETESDYEPKNKV---------KSRKP----------- 193
Query: 1308 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR 1367
+ ++K K K++ G+ +R++ S SEE + ED +
Sbjct: 194 ---------QNRSKSKNGKKILGQKKRQIDS-------------SEEDDDEEDYDNDKRS 231
Query: 1368 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1427
S ++A + SYK+ E K++S++ E E+ + EEEE E +
Sbjct: 232 SRRQATVNV---SYKE-------------DEEMKTDSDDLLEVCGEDVPQPEEEEFETIE 275
Query: 1428 ENDDSKSPGKG 1438
D + KG
Sbjct: 276 RFMDCRIGRKG 286
Score = 43.5 bits (101), Expect = 0.003
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 28/271 (10%)
Query: 736 DDKGKRKRKSSTSGSDFDTKKGK---SAKSSIISKKKRQTQSESSNYDSELEKEIKSMSK 792
D++ R +S SD D+ S SS S +QS SS+ DS E +S S+
Sbjct: 6 DEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESE 65
Query: 793 IGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSS 852
+R K + K D +E K S + Q LK Q+ +++Q++ SS
Sbjct: 66 SDTSRENKVQAKPPK-VDGAEFWKSSPSILAVQRSAILKKQQQ------QQQQQQHQASS 118
Query: 853 AEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSK--- 909
G+ ++D++ E D + + D ++SG S + E +EKS
Sbjct: 119 NSGS-EEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDE 177
Query: 910 -------HLKTKTCKKVQDGLSDIAEKFL--KKDQSDETSEDDKKQSKKGTEEKKKPSDF 960
K K+ K S +K L KK Q D + EDD ++ + +
Sbjct: 178 TESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQAT 237
Query: 961 KKKVIKMEQQYESSSDGT-----EKLPEREE 986
K +++ ++ SD E +P+ EE
Sbjct: 238 VNVSYKEDEEMKTDSDDLLEVCGEDVPQPEE 268
Score = 39.7 bits (91), Expect = 0.037
Identities = 48/267 (17%), Positives = 97/267 (36%), Gaps = 27/267 (10%)
Query: 1003 DGEKKSKKIRDKTSKKKDELSDYAEKS-TGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1061
+G + +R+ + + D S +G G S SS D S + +
Sbjct: 2 NGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQ 61
Query: 1062 SSRKRQDCSSSDTEKYSMKEDGCN---SSDKRL---------KRIELRERRNLSSKRNTK 1109
S + + + K DG SS L K+ + ++++ + N+
Sbjct: 62 SESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSG 121
Query: 1110 EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSD 1169
+ SSS D+++SS + K+KK + + + + S S + ++ + SD
Sbjct: 122 SEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESD 181
Query: 1170 IEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP 1229
E +N + + + + K +L SS + DDD++D D
Sbjct: 182 YE--PKNKV-KSRKPQNRSKSKNGKKILGQKKRQIDSSEE-----------DDDEEDYDN 227
Query: 1230 ENRIAKKMLLEEIKANLSSDEDGSSDD 1256
+ R +++ + + SDD
Sbjct: 228 DKRSSRRQATVNVSYKEDEEMKTDSDD 254
Score = 38.5 bits (88), Expect = 0.082
Identities = 57/277 (20%), Positives = 94/277 (33%), Gaps = 49/277 (17%)
Query: 690 NSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSG 749
+SD + + E S+ S S + ++ + +Q+G D S S
Sbjct: 4 HSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSE 63
Query: 750 SDFDTKKGKSA-----------------------KSSIISKKKRQTQSESSNYDSELEKE 786
S+ DT + +S+I+ K+++Q Q + S E
Sbjct: 64 SESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSE 123
Query: 787 IKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE 846
S S ++D D S E KK D + S S D+E ++E
Sbjct: 124 EDSSS--------------SEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEE 169
Query: 847 RETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKE 906
RE S E D + +++ R P Q S S +G L K++ S E E +
Sbjct: 170 REKSSCDETESDYEPK-NKVKSRKP--QNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYD 226
Query: 907 KSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDD 943
K + K+D+ +T DD
Sbjct: 227 NDKRSSRRQA---------TVNVSYKEDEEMKTDSDD 254
Score = 38.1 bits (87), Expect = 0.11
Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 38/241 (15%)
Query: 876 ASASTDGVDKLSGKEQSFTSLEVRKVAETK-EKSKHLKTKTCKKVQDG----------LS 924
+ +S+DG SG S + E +E++ + S+ K + DG L+
Sbjct: 36 SGSSSDGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILA 95
Query: 925 DIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPER 984
LKK Q + + + S G+EE S E +SSS+ K +
Sbjct: 96 VQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSS---------EDSDDSSSEVKRKKHKD 146
Query: 985 EEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKS 1044
E+ G + + +S++ R+K+S + E SDY K+ K S KS
Sbjct: 147 EDWQMSGSG----SPSQSGSDSESEEEREKSSCDETE-SDYEPKN--KVKSRKPQNRSKS 199
Query: 1045 KNGAYGREKKRCKLLGKSSRKRQ-DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLS 1103
KNG K+LG+ +KRQ D S D ++ D +S + + +E +
Sbjct: 200 KNGK--------KILGQ--KKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYKEDEEMK 249
Query: 1104 S 1104
+
Sbjct: 250 T 250
Score = 35.4 bits (80), Expect = 0.70
Identities = 63/336 (18%), Positives = 122/336 (36%), Gaps = 51/336 (15%)
Query: 1134 TSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTE 1193
+S ++KA K K S++ + K S EDDD+ S + E+ K
Sbjct: 1328 SSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLSESKSDGRERSKKS--- 1384
Query: 1194 NLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA---NLSSDE 1250
+S +SG+ PV + ++ ++ D + K + +KA L E
Sbjct: 1385 --SVSDAPVHITASGE-------PVPISEESEELDQKTFSICKERMRPVKAALKQLDRPE 1435
Query: 1251 DGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESK----------KPRYRH 1300
G S+ E E ++ + ++ E K N E ++ R H
Sbjct: 1436 KGLSEREQLEHTRQCLIKIGDHI-TECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLH 1494
Query: 1301 RLLRH---KLTVSDGESGEEKKTKP-----KEHKEVKGRNRRKVSSEDSEDSD------- 1345
+L +H K S S + P + + +K SS DS SD
Sbjct: 1495 KLYKHAIKKRQESQQNSDQNSNLNPHVIRNPDVERLKENTNHDDSSRDSYSSDRHLTQYH 1554
Query: 1346 --FQESGVSEEVSESEDEQRPRTRSAKKAE------LEENQRSYKQKKKRRRIKVQEDSS 1397
++ + +S+ +RP + + + +++ R Y ++K R K+ + S
Sbjct: 1555 DHHKDRHQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHR--KLDDHRS 1612
Query: 1398 SENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSK 1433
+++SN E +++ + + D S+
Sbjct: 1613 RDHRSNLEGSLKDRSHSDHRSHSDHRLHSDHRSSSE 1648
Score = 35.0 bits (79), Expect = 0.91
Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 17/118 (14%)
Query: 25 SSEESEETSSPPRLAMNQNTD-KISGSGSNSDM---MENSKEEGTSSSEKSKSS------ 74
SSE+S+++SS + +++ D ++SGSGS S E+ +E SS ++++S
Sbjct: 128 SSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNK 187
Query: 75 -------GSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKED 125
S+SK I+ + D DD+ + D +S T+ KED
Sbjct: 188 VKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYKED 245
Score = 34.3 bits (77), Expect = 1.6
Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 23/103 (22%)
Query: 24 HSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKP 83
HS EES SS + ++ SGSGS S G+SS S SGS
Sbjct: 4 HSDEESVRNSSGESSQSDDDSGSASGSGSGS-------SSGSSSDGSSSQSGS------- 49
Query: 84 SIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKEDG 126
SD + + + +E S+ + EN + + PK DG
Sbjct: 50 --------SDSDSGSESGSQSESESDTSRENKVQAKP-PKVDG 83
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 112 bits (279), Expect = 6e-24
Identities = 126/599 (21%), Positives = 237/599 (39%), Gaps = 53/599 (8%)
Query: 904 TKEKSKHLKTKTCKKVQDGLSDIAEK--FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFK 961
+ EKS L +K Q + ++ + + D SDE E + + K ++ F
Sbjct: 510 SNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIF- 568
Query: 962 KKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKI----RDKTSK 1017
+ + E+ SD ++PE +E KG I+ + +++ K+ ++KT
Sbjct: 569 --MTQPATTIEAFSDEEVEIPEEKEGAEDSKG-NGIEEQEVEANEENVKVHGGRKEKTEI 625
Query: 1018 KKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKY 1077
D+L+D AE S GK S +ED G GR C+ + QD EK
Sbjct: 626 LSDDLTDKAEVSEGKAKSVGEAED-----GPEGRGDGTCEEGSSGAEHWQDEEREKGEKD 680
Query: 1078 S----MKEDGCNSSDKRLKRI---------ELRERRNLSSKRNTKEIQSGSSSS--DAEE 1122
M+ G + K E +ER K +E++ G + EE
Sbjct: 681 KGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEE 740
Query: 1123 SSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNS----I 1178
D ++++++ K+ +E + + +RK+ + E+ DQ
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEE 800
Query: 1179 GEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKML 1238
EG +E++ E + G + +E + ++++ + + E K
Sbjct: 801 TEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE 860
Query: 1239 LEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRY 1298
E E+G + E EEG+ ++ E +EE + + E + + EE +
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE---- 916
Query: 1299 RHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSES 1358
+G+ EE + E +E +G + + E+ + + G EE
Sbjct: 917 -----------GEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE 965
Query: 1359 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1418
+E+ + E EE + + +++ + +E+ E + E EEEE+ E E E
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEV 1025
Query: 1419 EEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERERE 1477
E EE E E E ++ + G+ R+K + ++ + R E + EEE + + E E ER+
Sbjct: 1026 EGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEE----EEEGKYQETGEEENERQ 1080
Score = 102 bits (253), Expect = 6e-21
Identities = 141/730 (19%), Positives = 279/730 (38%), Gaps = 105/730 (14%)
Query: 754 TKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR----------- 802
TK+ + SS + T + + L KS+ K+ + KK+
Sbjct: 479 TKEAEIDNSSTVESLGETTDILNMTHIMSLNSNEKSL-KLSPVQKQKKQQTIGELTQDTA 537
Query: 803 IPNTKDFDSSEDEKHSKKGMDNQGH--KNLKTSQEGSSDDAERKQERETFSSAEGTVDKD 860
+ D D E+ K+G + H + + +Q ++ +A +E E EG D
Sbjct: 538 LTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSK 597
Query: 861 TTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQ 920
+E +Q+ A+ + V K+ G + T + + + E S+ K K+ + +
Sbjct: 598 GNGIE-------EQEVEANEENV-KVHGGRKEKTEILSDDLTDKAEVSEG-KAKSVGEAE 648
Query: 921 DGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEK 980
DG + + D T E+ ++ +E+++ + K +ME+ E G ++
Sbjct: 649 DG---------PEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE----GEKE 695
Query: 981 LPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKK--DELSDYAEKSTGKGDSCDS 1038
L E+EE DGE++ +K R++ +K+ E+ + E+ G+G+ +
Sbjct: 696 LAEKEEW------------KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG 743
Query: 1039 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1098
+++ + G+E+ + E KE+G ++R + E E
Sbjct: 744 DREEEEEKEGEGKEEGE---------------GEEVEGEREKEEGERKKEERAGKEEKGE 788
Query: 1099 RRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1158
+ G EE +E ++K+ + + E+ + +
Sbjct: 789 -------------EEGDQGEGEEEETEGRGEEKEEGGEVEGGEV--EEGKGEREEEEEEG 833
Query: 1159 QADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPV 1218
+ + + E + + GEG +E+ G + G+E +
Sbjct: 834 EGEEEEGEGEEEEGEGEEEEGEGKGEEE------------GEEGEGEEEGEEGEGEG--- 878
Query: 1219 TVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD--E 1276
++++ + E + EE + +E+G + E EEG+ + ++ EE G+ E
Sbjct: 879 ----EEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 1277 EAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKV 1336
E + + + EE + +GE E+ E +E +G +
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEE 994
Query: 1337 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDS 1396
E+ E+ + G E E E+E+ + E E + ++ ++ + +E
Sbjct: 995 GEEEGEE---EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGE 1051
Query: 1397 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRK-ILKDDKLRTET 1455
EN+ N EEEEEE+ + +E EEE E ++ E S KG K K K T T
Sbjct: 1052 GEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNT 1111
Query: 1456 QNALKEEEER 1465
Q KE+ +
Sbjct: 1112 QGNGKEQRSK 1121
Score = 86.7 bits (213), Expect = 3e-16
Identities = 98/414 (23%), Positives = 181/414 (43%), Gaps = 45/414 (10%)
Query: 1085 NSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVK 1144
NS++K LK +++++ K+ G + D + D+ + + S K+ K
Sbjct: 509 NSNEKSLKLSPVQKQK--------KQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACK 560
Query: 1145 EKKRNSLRTSTKRKQADITSSSSSDIEDDDQ---NSIGEGSSDEQKIKPVTENLVLSSHT 1201
+ + + + S +I ++ + +S G G +EQ+++ EN+ + H
Sbjct: 561 QHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGI-EEQEVEANEENVKV--HG 617
Query: 1202 GFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSD---EDGSS---- 1254
G + E LS DD D + AK + E D E+GSS
Sbjct: 618 G--RKEKTEILS-------DDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEH 668
Query: 1255 --DDEPEEGKKRTGKQNEENPGDEE---AKNQVNSESDSDSEESKKPRYRHRLLRHKLTV 1309
D+E E+G+K G+ E PG+ E A+ + + D + +E K+ H+ R++
Sbjct: 669 WQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEME 728
Query: 1310 SDGES----GEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPR 1365
GE GEE++ +E +E +G + + E+ E +E G ++ + E++
Sbjct: 729 EGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGE 788
Query: 1366 TRSAK-KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE 1424
+ + E EE + ++K++ ++ E + + EEEE E EEEE E EEEE E
Sbjct: 789 EEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848
Query: 1425 EEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREK 1478
E+E + K +G + + ++ E + +EEE + E E E E+
Sbjct: 849 GEEEEGEGKGEEEGEEG-----EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Score = 73.9 bits (180), Expect = 2e-12
Identities = 113/564 (20%), Positives = 214/564 (37%), Gaps = 49/564 (8%)
Query: 921 DGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT-E 979
+G ++ FL SE + ++S ++ +P + + +M ++ E + T E
Sbjct: 432 EGTLGLSACFLPNSVFPRCSERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVE 491
Query: 980 KLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSS 1039
L E +I + + N +KS K+ +KK + + T ++ DS
Sbjct: 492 SLGETTDILNMTHIMSLNSN------EKSLKLSPVQKQKKQQTIGELTQDTALTENDDSD 545
Query: 1040 EDKKSKNGAYGREKKRCKLLGK-SSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1098
E ++ G+ K+ G ++ + E+ + E+ + D + IE +E
Sbjct: 546 EYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQE 605
Query: 1099 RRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1158
+++ N K G E S+D K + + K K+V E T +
Sbjct: 606 VE--ANEENVKV--HGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEE 661
Query: 1159 QADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPV 1218
SS ++ D++ GE +++ E G++ L++
Sbjct: 662 -----GSSGAEHWQDEEREKGEKDKGRGEMERPGE--------------GEKELAEKEEW 702
Query: 1219 TVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEP---EEGKKRTGKQNEENPGD 1275
D ++ E + + +E G ++E EE +++ G+ EE G+
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE 762
Query: 1276 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1335
E V E + + E KK R + + +G+ GE E +E +GR K
Sbjct: 763 E-----VEGEREKEEGERKK---EERAGKEEKGEEEGDQGEG------EEEETEGRGEEK 808
Query: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1395
+ E + +E E E E E ++ E E + + K + + + +
Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868
Query: 1396 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEND-DSKSPGKGRKKIRKILKDDKLRTE 1454
E EEEE + E EEE E E EEEE E + + + G+G ++ + +++
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928
Query: 1455 TQNALKEEEERRKRIAEREREREK 1478
+EE E E E E E+
Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEE 952
Score = 52.4 bits (124), Expect = 6e-06
Identities = 53/264 (20%), Positives = 109/264 (41%), Gaps = 5/264 (1%)
Query: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDS 1288
P + K+ + E+ + + E+ SD+ E + + GK +++ Q + ++
Sbjct: 519 PVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEA 578
Query: 1289 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQE 1348
S+E + + S G EE++ + E + VK RK +E D +
Sbjct: 579 FSDEEVEIPEE----KEGAEDSKGNGIEEQEVEANE-ENVKVHGGRKEKTEILSDDLTDK 633
Query: 1349 SGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEE 1408
+ VSE ++S E EE + + R K ++D E E
Sbjct: 634 AEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGE 693
Query: 1409 EEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKR 1468
+E E+EE ++ + EE+E + + + +++ + +++ E + +EEEE ++
Sbjct: 694 KELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEG 753
Query: 1469 IAEREREREKLREVIEIEDASPTK 1492
+ E E E++ E E+ K
Sbjct: 754 EGKEEGEGEEVEGEREKEEGERKK 777
Score = 32.3 bits (72), Expect = 5.9
Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Query: 407 KGEKPCALEKKDISKSEAKLSRKQVDSEHMHQ---NVPTEEQRTNKSTGGEHKKSDRKEE 463
+GEK A EK++ K + + ++Q + E HQ N EE + GE ++ DR+EE
Sbjct: 691 EGEKELA-EKEEWKKRDGE-EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Query: 464 PQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVE 519
+ E E ++ E+ E + + +GD G E+E E
Sbjct: 749 EEKEGEGKEEGEGEEVEG--EREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE 802
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 112 bits (279), Expect = 6e-24
Identities = 66/180 (36%), Positives = 101/180 (56%), Gaps = 23/180 (12%)
Query: 1973 AEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLI 2032
+ +++ SGK++LL ++L+ + G +VL+FSQ LDL+EDFLE
Sbjct: 1017 SSLVKSSGKLMLLQKMLKKLRDEGHRVLIFSQMTKMLDLLEDFLE--------------- 1061
Query: 2033 YKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAAN 2092
Y+G Y R+DG T R++ + FN + F++ST+AG LGINL A+
Sbjct: 1062 YEG-------YKYERIDGGITGGLRQEAIDRFN-APGAQQFCFLLSTRAGGLGINLATAD 1113
Query: 2093 RVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVV 2152
VII+D+ WNP DIQ+ R +R GQ K V +YRF+ + ++E++I K L+ VV
Sbjct: 1114 TVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVV 1173
Score = 97.1 bits (240), Expect = 2e-19
Identities = 88/334 (26%), Positives = 150/334 (44%), Gaps = 42/334 (12%)
Query: 1522 LKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDF 1581
L P+Q++G+ ++ + + G+ ILA MGLGKT+Q + FL++ L +
Sbjct: 700 LHPYQLEGLNWL---------RFSWAQGTDTILADEMGLGKTVQTIVFLYS-LYKEGHSK 749
Query: 1582 STALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVM 1641
LV PL+T +NW EFE W E +V R E S+ ED +
Sbjct: 750 GPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSF------EDNAIR 803
Query: 1642 IIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGP------DFVVCDEGHILKNEASAVSK 1695
G +++R + + +K L + +D +V DE H LKN S +
Sbjct: 804 S-GKKVFR-MKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQSKFFR 861
Query: 1696 AMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADST 1755
+NS + +++LTGTPLQNNL E ++NF+ +++ F F + + Q
Sbjct: 862 VLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQ----- 916
Query: 1756 MVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDH 1815
+KK L+++L + R+ + K +P K E ++ V ++ +Q K Y++ L
Sbjct: 917 ------IKK----LHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTR 966
Query: 1816 LTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPW 1849
N+ GG + + D L + HP+
Sbjct: 967 NFEALNSKGGGNQVSLLNIMMD---LKKCCNHPY 997
Score = 42.7 bits (99), Expect = 0.004
Identities = 46/201 (22%), Positives = 77/201 (38%), Gaps = 38/201 (18%)
Query: 57 MENSKEEGTSSSEKSKS----------SGSSRSKRKPSIVTKYVESDDEKPLDDETVNED 106
+ N +++G+SS E + S S RS+ ++ K +K +DD E
Sbjct: 281 ISNKRKKGSSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGYET 340
Query: 107 ASNENSENDITMQSLPKEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYY 166
+ E + ++ G I+ C C + + D C +C K
Sbjct: 341 DHQDYCE-------VCQQGG--EIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEG 391
Query: 167 MS-----DDISRDSDGMDEQ-------CRWCAEGGNLICCDFCHNAFCKKCILRNLGRKE 214
+ DD + G +E+ CR C +GG L+CCD C +++ C+ N E
Sbjct: 392 IQWEPKDDDDEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCL--NPPLPE 449
Query: 215 LSTIMDENNQWYCYICHPEPL 235
+ N +W C C PL
Sbjct: 450 I-----PNGEWLCPRCTCPPL 465
Score = 41.6 bits (96), Expect = 0.010
Identities = 24/95 (25%), Positives = 50/95 (52%), Gaps = 18/95 (18%)
Query: 1318 KKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEEN 1377
KK KPK+ KE K + +RK ++ G ++E+SE+E++ ++ S E
Sbjct: 49 KKKKPKKLKENKCKGKRK-----------KKEGSNDELSENEEDLEEKSES-------EG 90
Query: 1378 QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKE 1412
KKK++++K +++ ++ K E+E++ +
Sbjct: 91 SDYSPNKKKKKKLKDKKEKKAKRKKKDEDEDDNDD 125
Score = 41.6 bits (96), Expect = 0.010
Identities = 28/122 (22%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Query: 1309 VSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1368
+ + + G +K +P E + + R V SED +S + EE E ++ P
Sbjct: 1576 MDEKDPGAQKPRQPLEVQALPAALDR-VESEDKHESPASKERAREERPEETEKAPPSPEQ 1634
Query: 1369 AKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1428
+ E+ + K + I + DSS +++ EE+E E ++ ++EE++E +
Sbjct: 1635 LPREEVLPEKEKILDKLELSLIHSRGDSSELRPDDTKAEEKEPIETQQNGDKEEDDEGKK 1694
Query: 1429 ND 1430
D
Sbjct: 1695 ED 1696
Score = 40.0 bits (92), Expect = 0.028
Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 17/134 (12%)
Query: 1340 DSEDSDFQESGVS--EEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSS 1397
+ E S+ ++ G+ ++ E P+ + KK L+EN+ K+KKK
Sbjct: 22 EDEMSEEEDGGLEAFDDFFPVEPVSLPKKKKPKK--LKENKCKGKRKKKEG--------- 70
Query: 1398 SENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN 1457
SN E E E++ EE+ E E + ++ K K KK ++ KD+
Sbjct: 71 ----SNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKKAKRKKKDEDEDDNDDG 126
Query: 1458 ALKEEEERRKRIAE 1471
LKE + + +AE
Sbjct: 127 CLKEPKSSGQLMAE 140
Score = 39.7 bits (91), Expect = 0.037
Identities = 76/382 (19%), Positives = 148/382 (38%), Gaps = 43/382 (11%)
Query: 905 KEKSKHLKTKTCKKVQ-------DGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKP 957
K+K K LK CK + D LS+ E +K +S+ + K+ KK ++KK+
Sbjct: 50 KKKPKKLKENKCKGKRKKKEGSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEK 109
Query: 958 SDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSK 1017
K K K ++ + + DG K P+ G + G D + + T
Sbjct: 110 ---KAKRKKKDEDEDDNDDGCLKEPK-------SSGQLMAEWGLDDVDYLFSEEDYHTLT 159
Query: 1018 KKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGRE-KKRCKLLGKSSRKRQDCSSSDTEK 1076
S + K + + GA RE G S+ ++ E
Sbjct: 160 NYKAFSQFLRPLIAKKNPKIPMSKMMTVLGAKWREFSANNPFKGSSAAAAAAAVAAAVET 219
Query: 1077 YSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSS 1136
++ S + + + +R K TKE + + S + KK K + ++
Sbjct: 220 VTISPPLAVSPPQVPQPVPIR-------KAKTKEGKGPGVRKKIKGSKDGKKKGKGKKTA 272
Query: 1137 KKK---AVIVKEKKRNSLRTSTKRKQADITSSS--SSDIEDDDQNSIGEGSSDEQKIKPV 1191
K I ++K+ S +R+++D S+S S+ + + ++G+ S +K K +
Sbjct: 273 GLKFRFGGISNKRKKGSSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRI 332
Query: 1192 TE-NLVLSSHTGF---CQSSGDEALSKSVP----VTVDDDDDDNDPENR-----IAKKML 1238
+ + + H + CQ G+ L + P + D + + PE + K+ +
Sbjct: 333 DDGDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGI 392
Query: 1239 LEEIKANLSSDEDGSSDDEPEE 1260
E K + +E+G ++E ++
Sbjct: 393 QWEPKDDDDEEEEGGCEEEEDD 414
Score = 37.0 bits (84), Expect = 0.24
Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 15/136 (11%)
Query: 950 GTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSK 1009
GTEE+ P F +++ ++ E G E + + P + + K E K K
Sbjct: 6 GTEEEL-PRLFAEEMENEDEMSEEEDGGLEAFDDFFPV--EPVSLPKKKKPKKLKENKCK 62
Query: 1010 KIRDKTSKKKDELS----DYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRK 1065
R K DELS D EKS +G D S +KK K +++K+ K RK
Sbjct: 63 GKRKKKEGSNDELSENEEDLEEKSESEGS--DYSPNKKKKKKLKDKKEKKAK------RK 114
Query: 1066 RQDCSSSDTEKYSMKE 1081
++D D + +KE
Sbjct: 115 KKDEDEDDNDDGCLKE 130
Score = 35.8 bits (81), Expect = 0.53
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 17/85 (20%)
Query: 1259 EEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEK 1318
+E K + ++ +E DE ++N+ + E S+SE S D ++K
Sbjct: 57 KENKCKGKRKKKEGSNDELSENEEDLEEKSESEGS-----------------DYSPNKKK 99
Query: 1319 KTKPKEHKEVKGRNRRKVSSEDSED 1343
K K K+ KE K + ++K ED D
Sbjct: 100 KKKLKDKKEKKAKRKKKDEDEDDND 124
Score = 35.8 bits (81), Expect = 0.53
Identities = 22/113 (19%), Positives = 46/113 (40%), Gaps = 1/113 (0%)
Query: 1323 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1382
+E V+ R + E++ D D+ E + + +++ K+ + N
Sbjct: 1296 REEDGVEEVEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDAS 1355
Query: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
Q+ + + ++ D+ SE SE+E+E+ EE E + + D P
Sbjct: 1356 QEDQEWQDELS-DNQSEYSIGSEDEDEDFEERPEGQSGRRQSRRQLKSDRDKP 1407
Score = 34.7 bits (78), Expect = 1.2
Identities = 32/167 (19%), Positives = 72/167 (43%), Gaps = 17/167 (10%)
Query: 1309 VSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRS 1368
V + G + K+H + + V EDS + ++ +S+ + ++D +
Sbjct: 1222 VQSSKGGNLAASAKKKHGSTPPGDNKDV--EDSSVIHYDDAAISKLLDRNQD-------A 1272
Query: 1369 AKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1428
EL+ K + + +ED E + ++EE + + E+ E+ +
Sbjct: 1273 TDDTELQNMNEYLSSFKVAQYVVREEDGVEEVEREIIKQEENVDPDYWEKLLRHHYEQQQ 1332
Query: 1429 NDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAERERE 1475
D +++ GKG K+IRK + +A +E++E + +++ + E
Sbjct: 1333 EDLARNLGKG-KRIRK-------QVNYNDASQEDQEWQDELSDNQSE 1371
Score = 34.7 bits (78), Expect = 1.2
Identities = 29/143 (20%), Positives = 62/143 (43%), Gaps = 4/143 (2%)
Query: 1321 KPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRS 1380
KP++ EV+ + + E D ES S+E + E + +L +
Sbjct: 1585 KPRQPLEVQAL---PAALDRVESEDKHESPASKERAREERPEETEKAPPSPEQLPREEVL 1641
Query: 1381 YKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRK 1440
+++K ++++ S + S ++ + EE+E E ++ ++E++++ K KG+
Sbjct: 1642 PEKEKILDKLELSLIHSRGDSSELRPDDTKAEEKEPIETQQNGDKEEDDEGKKEDKKGKF 1701
Query: 1441 KIRKILKDDKLRTETQNALKEEE 1463
K + D TE + EE
Sbjct: 1702 KFMFNIADGGF-TELHTLWQNEE 1723
Score = 33.1 bits (74), Expect = 3.5
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 12/112 (10%)
Query: 1347 QESGVSE---EVSESEDEQRPR-----TRSAKKAELEENQRSYKQKKKRRRIKVQEDSSS 1398
+E GV E E+ + E+ P R + + E+ R+ + K+ R+ D+S
Sbjct: 1297 EEDGVEEVEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDASQ 1356
Query: 1399 ENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK 1450
E++ +E + + E E+E+E+ E+ + GR++ R+ LK D+
Sbjct: 1357 EDQEWQDELSDNQSEYSIGSEDEDEDFEERPEGQ----SGRRQSRRQLKSDR 1404
Score = 32.7 bits (73), Expect = 4.5
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 5/86 (5%)
Query: 1407 EEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERR 1466
EE E E+E EEE+ E D+ + +KK K LK++K + + K++E
Sbjct: 17 EEMENEDEMSEEEDGGLEAFDDFFPVEPVSLPKKKKPKKLKENKCKGKR----KKKEGSN 72
Query: 1467 KRIAEREREREKLREVIEIEDASPTK 1492
++E E + E+ E E D SP K
Sbjct: 73 DELSENEEDLEEKSE-SEGSDYSPNK 97
>gi|21071044 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform a [Homo sapiens]
Length = 1054
Score = 111 bits (278), Expect = 8e-24
Identities = 67/194 (34%), Positives = 104/194 (53%), Gaps = 33/194 (17%)
Query: 1972 DAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPL 2031
D ++ +SGKMV+L ++L +E G +VL+FSQ LD++ED+
Sbjct: 478 DEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYC--------------- 522
Query: 2032 IYKGEGKWLRNIDYYRLDGSTTAQSRK-----------KWAEEFNDETNVRGRLFIISTK 2080
W R +Y RLDG T + R+ + A E + N +F++ST+
Sbjct: 523 ------MW-RGYEYCRLDGQTPHEEREDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTR 575
Query: 2081 AGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDR 2140
AG LGINL +A+ VI++D+ WNP D+Q++ R +R GQ KPV V+R + T+E++I +R
Sbjct: 576 AGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVER 635
Query: 2141 QVTKQSLSFRVVDQ 2154
K L V+ Q
Sbjct: 636 AEIKLRLDSIVIQQ 649
Score = 92.8 bits (229), Expect = 4e-18
Identities = 124/526 (23%), Positives = 211/526 (40%), Gaps = 97/526 (18%)
Query: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL--EENQRSYKQKKKRRRIKVQ 1393
+ E S QE G + +E+ T + +K E E+N S++ K + K
Sbjct: 24 IEDEQPGPSTSQEEGAAAAATEA-------TAATEKGEKKKEKNVSSFQLKLAAKAPK-- 74
Query: 1394 EDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE-----DENDDSKSPGKGRKKIRKILKD 1448
SE + + E EE+ K + + E ++ E + KSP + L
Sbjct: 75 ----SEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSP---TSPLNMKLGR 127
Query: 1449 DKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETK 1508
+++ + + +L + R R E+E + E L E S + + +
Sbjct: 128 PRIKKDEKQSLISAGDYRHRRTEQEEDEELLSE-------SRKTSNVCIRFEVSPSYVKG 180
Query: 1509 EPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVS 1568
PL + +Q+ G+ ++ G ILA MGLGKTLQ ++
Sbjct: 181 GPL-----------RDYQIRGLNWLISLY---------ENGVNGILADEMGLGKTLQTIA 220
Query: 1569 FLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGLK-----DDEKLEVSELATVKR 1623
L + + +V+ P +T NWMNEF++W L+ D+ + +
Sbjct: 221 LLGYLKHYRNIP-GPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMM 279
Query: 1624 PQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEG 1683
P E W V + YEM +K + + + F+ ++V DE
Sbjct: 280 PGE-------WD----VCVTSYEMV--------IKEKSVFKKFHWR-------YLVIDEA 313
Query: 1684 HILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFI 1743
H +KNE S +S+ + +S R++LTGTPLQNNL E ++NF+ ++ S +F + F
Sbjct: 314 HRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWF- 372
Query: 1744 NPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTS 1803
C +K L+ +L + R+ T + K LPPK E + + ++
Sbjct: 373 ---DTKNCLGD--------QKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSK 421
Query: 1804 IQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTHPW 1849
+Q + Y L V NS G K +L L + HP+
Sbjct: 422 MQREWYTKILMKDIDV-LNSSGKMDK--MRLLNILMQLRKCCNHPY 464
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 110 bits (276), Expect = 1e-23
Identities = 188/901 (20%), Positives = 358/901 (39%), Gaps = 108/901 (11%)
Query: 639 SDEECNETVKEKQKLSVPVR-----KKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDS 693
S E N E+ +P + DK +S+ D K + ET ++ +
Sbjct: 221 STETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEF 280
Query: 694 DEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKD-DKGKRKRKSSTSGSDF 752
++ ++E+ + + N I N + Q K DKG++K S+ G
Sbjct: 281 SDLPCPVEEIKNYTKEHN-----NLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERK 335
Query: 753 DTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTK-KRIPNTKDFDS 811
KK K+ K SKK TQ ++ EKE++S+ + K K + TK+ S
Sbjct: 336 KEKKEKTEKKFDHSKKSEDTQKVKDEKQAK-EKEVESLKLPSEKNSNKAKTVEGTKEDFS 394
Query: 812 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP 871
D G+ + ++ TS S ++ ++ + S EG + D
Sbjct: 395 LIDS--DVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDE--------E 444
Query: 872 KKQQASASTDGVDKLSGKEQSFTSLEVRK-VAETKEKSKHLKTKTCKKVQDGLS-DIAEK 929
K +Q T D GK +S V K +K S T ++ + ++ + E+
Sbjct: 445 KNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEER 504
Query: 930 FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICH 989
L++ + E E+ +KQ + T+ K + V ESS+ E R +
Sbjct: 505 LLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSV----DLEESSTKSLEPKAARIKEVL 560
Query: 990 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKN--- 1046
+ + + K + KK + ++ SKKK + + ++++ + C+ + SK
Sbjct: 561 KERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKH 620
Query: 1047 -GAYGREKKRCKLLGKS-------------SRKRQDCSSSDTEKYSMKEDGCNSSDKR-L 1091
A K + L +S R+ + +S+ ++E+ KR +
Sbjct: 621 VHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQV 680
Query: 1092 KRIEL---RERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKR 1148
+R E+ ++ S+ +N K ++ D+E + KK+ SSK+K +EK
Sbjct: 681 ERSEICTEEPQKQKSTLKNEKHLKK----DDSETPHLKSLLKKEVKSSKEKPE--REKTP 734
Query: 1149 NSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSS- 1207
+ + S K K + D + + +S +G E+ I+ ++ LSS + S
Sbjct: 735 SEDKLSVKHKYKGDCMHKTGD--ETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSK 792
Query: 1208 ----------GDEALSKSVPVTVDDDD---DDNDPENRIAKKMLLEEIKANLSSDEDGSS 1254
G + S + D++ ++N E R++ + E K+ SSD
Sbjct: 793 HRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQK 852
Query: 1255 DDEPEEGKKRTG----KQNEENPGDEEAKNQVNSESDSDSEE--SKKPRYRHRLLRHKLT 1308
D G K+ G +++E D+ + N +S+ EE K+ R LL KL
Sbjct: 853 DSL---GSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLV 909
Query: 1309 VS------------------DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG 1350
+ +G + + KP + K + + K ED F+E+G
Sbjct: 910 LKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETG 969
Query: 1351 VSEEVSESEDEQRPRTR--SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS--EE 1406
V E V E+ T+ S+ +A+L + YK K +++ S +KS S
Sbjct: 970 V-EPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHS 1028
Query: 1407 EEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG---RKKIRKILKDDKLRTETQNALKEEE 1463
++ K+++E + ++++ +E D + + K+ G KK+ + L +++ + +Q K EE
Sbjct: 1029 SKDIKKKDENKSDDKDGKEVDSSHE-KARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEE 1087
Query: 1464 E 1464
+
Sbjct: 1088 K 1088
Score = 97.8 bits (242), Expect = 1e-19
Identities = 209/1060 (19%), Positives = 399/1060 (37%), Gaps = 147/1060 (13%)
Query: 374 DLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDS 433
D S + ++N+E + + +T R +K + D S + + S D
Sbjct: 200 DAMSILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADK 259
Query: 434 EHMHQNVPTEEQRTNKSTGGEHKKSDRKEE-------PQYEPANTSEDLDMDIVSVPSSV 486
E ++ +GGE ++ K E P E N +++ + +++ + V
Sbjct: 260 E-----------KSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHN-NLILLNKDV 307
Query: 487 PEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTK 546
+ E++ + S D +G+ + ++ E K + K KS+ T KV
Sbjct: 308 QQ------ESSEQKNKSTD-KGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKD 360
Query: 547 ELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEV 606
E K K + ++P +K+ K+ + E L +SD + L + V
Sbjct: 361 EKQAKE----------KEVESLKLPSEKNSNKAKTVEGTKEDFSL--IDSDVDGLTDITV 408
Query: 607 SLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSS 666
S + SDL + TE VTS+S EE T +++K + K K +S
Sbjct: 409 SSV-HTSDL--------SSFEEDTEEEVVTSDSMEEGEITSDDEEKNK---QNKTKTQTS 456
Query: 667 DSAIDNPKPNKLPKSKQSETVDQN-SDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKT 725
DS+ K + + + SDSD+ L + E R S + + + N +
Sbjct: 457 DSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTV--EQRRQSIAKEKEERLLRRQINREK 514
Query: 726 LYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEK 785
L + + Q + K + + S D + KS + K+ + + L K
Sbjct: 515 LEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSK 574
Query: 786 EIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQ 845
+ K S+ + KK+ ED K + K ++ + + +S+E A+ +
Sbjct: 575 KRKKDSRNVEENSKKKQ-------QYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEP 627
Query: 846 ERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETK 905
+ +E D E +L ++ + ST + + G ++ + +V++ E
Sbjct: 628 SKPARRLSESLHVVDENKNE--SKLEREHKRRTSTPVI--MEGVQEETDTRDVKRQVERS 683
Query: 906 EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETS-----EDDKKQSKKGTEEKKKPSDF 960
E + T+ +K + L + EK LKKD S+ + + K SK+ E +K PS+
Sbjct: 684 E----ICTEEPQKQKSTLKN--EKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSED 737
Query: 961 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1020
K V +++ D K + E+ KG+K +N ++ DKT +K
Sbjct: 738 KLSV-----KHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSK 792
Query: 1021 ELSDYAEKSTGK-GDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSM 1079
++ GK G K +N KK +L + ++ S K +
Sbjct: 793 HRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSK--I 850
Query: 1080 KEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDNKKK--------- 1130
++D S + +RR+ S + ++ S + S+ + +K+K
Sbjct: 851 QKDSLGSKQHGITL----QRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEE 906
Query: 1131 ------KQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184
K +T K+ V+ E + + + +T K ++ +D E ++ + + +
Sbjct: 907 KLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFE 966
Query: 1185 EQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKA 1244
E ++PV E S+H+ + D + +P+ + D D + ++ L + K+
Sbjct: 967 ETGVEPVLETASSSAHS----TQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKS 1022
Query: 1245 ---------------NLSSDEDGSSDDEPEEG-----------------KKRTGKQNEEN 1272
N S D+DG D E + R G ++E
Sbjct: 1023 RSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEM 1082
Query: 1273 PGDEE--AKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKG 1330
EE A N +++ S S + KK + + D E G E + K
Sbjct: 1083 AKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVS-----KT 1137
Query: 1331 RNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAK 1370
++ R +S+ DS+ + S V +DE R T +K
Sbjct: 1138 QDNRNNNSQQDIDSENMKQKTSATV--QKDELRTCTADSK 1175
Score = 94.7 bits (234), Expect = 1e-18
Identities = 159/830 (19%), Positives = 328/830 (39%), Gaps = 112/830 (13%)
Query: 776 SSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQE 835
S N ++ + S + K++P+ D+S D++ + + M ++ K++ +
Sbjct: 210 SLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKE----KSTAD 265
Query: 836 GSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTS 895
+ E + E FS D + E+++ + V + S ++++ ++
Sbjct: 266 SGGEGLETAPKSEEFS------DLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKST 319
Query: 896 LEVRKVAETKEKS---KHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTE 952
+ K ++ EK K K KT KK KK + + +D+K+ +K E
Sbjct: 320 DKGEKKPDSNEKGERKKEKKEKTEKKFDHS---------KKSEDTQKVKDEKQAKEKEVE 370
Query: 953 EKKKPSDFKKKVIK-----------MEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGT 1001
K PS+ K ++ + +D T ++ F + ++ + T
Sbjct: 371 SLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEE-EVVT 429
Query: 1002 TDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK-KSKNGAYGREKKRCKLLG 1060
+D ++ + D K K + K + DSSE K KS AY + L
Sbjct: 430 SDSMEEGEITSDDEEKNKQNKT--------KTQTSDSSEGKTKSVRHAYVHKPY---LYS 478
Query: 1061 KSSRKRQDCSSSDTEKYSM-KEDGCNSSDKRLKRIELRERRNLSSKR--NTKEIQSGSSS 1117
K D + + + S+ KE +++ R +L E+R +++ ++K G SS
Sbjct: 479 KYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSS 538
Query: 1118 SDAEESSEDNKKKK---------QRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSS 1168
D EESS + + K +R +KK + K++K++S K+ S
Sbjct: 539 VDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSK 598
Query: 1169 DIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDND 1228
+ ++ E S +++K V H S LS+S+ V D+N
Sbjct: 599 ETLKTSEHCEKEKISSSKELKHV--------HAKSEPSKPARRLSESLHVV-----DENK 645
Query: 1229 PENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE---ENPGDEEAKNQVNSE 1285
E+++ ++ + + + +G ++ KR +++E E P ++ K+ + +E
Sbjct: 646 NESKLERE---HKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEP--QKQKSTLKNE 700
Query: 1286 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1345
++S+ P + L K S E E +KT ++ VK + + + ++++
Sbjct: 701 KHLKKDDSETPHLKSLL--KKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETE 758
Query: 1346 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKK-----------KRRRIKVQE 1394
S +V E+ +Q +T+ + + E + ++K IK E
Sbjct: 759 LHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDE 818
Query: 1395 DSSSENKSNSEEEEEEKEEEEEEEEEEEEEE-EDENDDSKSPGKGRKKIRKILKDDKLRT 1453
+ EN EK + E + + + + ++ SK G ++ + +DK
Sbjct: 819 NVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDM 878
Query: 1454 ETQN---------ALKEEEERRKRIAE-------REREREKLREVIEIE-DASPTKCPIT 1496
++ N + +E+ R K + E + + + K +V+E E TK T
Sbjct: 879 DSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATT 938
Query: 1497 TKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKK 1546
K D+++ T+E + R ++ KP + GV+ + + S T+K
Sbjct: 939 PKP--DKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQK 986
Score = 88.2 bits (217), Expect = 9e-17
Identities = 223/1188 (18%), Positives = 450/1188 (37%), Gaps = 196/1188 (16%)
Query: 325 TANMNSSYVKFLKQATD-NSEISSATKLRQLKAFKSVLADIKK--AHLALEEDLNSEFRA 381
+AN+ + + L+ T N E S+A + K+ KK + + + E +
Sbjct: 194 SANVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTS 253
Query: 382 MDAVNKEKNTKEHKVIDAKFETKARK-GEKPCALEK-KDISKSEAKL-----SRKQVDSE 434
D +KEK+T + + K+ + + PC +E+ K+ +K L +Q SE
Sbjct: 254 EDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSE 313
Query: 435 HMHQNVPTEEQRTNKSTGGEHKKSDR-KEEPQYEPANTSEDL------------DMDIVS 481
+++ E++ + + GE KK + K E +++ + SED +++ +
Sbjct: 314 QKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLK 373
Query: 482 VPSSVPEDIFENLETAMEVQSSVDHQGDG-----------------SSGTEQEVESSSV- 523
+PS + + +E E S +D DG TE+EV +S
Sbjct: 374 LPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSM 433
Query: 524 ---KLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSC 580
++ ++ K+KT + E K + + P + D+
Sbjct: 434 EEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDE------ 487
Query: 581 GLNPKLEKCGLGQENSDNEHLVENEVSL-LLEESDLRRSPRVKTTPLRRPTETNPVTSNS 639
L + + + +E E L+ +++ LEE +++ + K++ + ++ S
Sbjct: 488 -LTVEQRRQSIAKEKE--ERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEES 544
Query: 640 DEEC--------NETVKEKQKLSVPV-----RKKDKRNSSDSA----------------I 670
+ E +KE++ L V RKKD RN +++
Sbjct: 545 STKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTS 604
Query: 671 DNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLK 730
++ + K+ SK+ + V S+ + L E + + +++ + H +T +
Sbjct: 605 EHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREH-KRRTSTPVI 663
Query: 731 TQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKK-RQTQSESSNYDSELEKEIKS 789
+ +++ R K S+ T++ + KS++ ++K ++ SE+ + S L+KE+KS
Sbjct: 664 MEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKS 723
Query: 790 MSKIGAARTTKKRIPNTKDFDSSEDE---KHSKKG--MDNQGHKN-LKTSQEGSS-DDAE 842
+ + +++ P SED+ KH KG M G + L +S++G ++
Sbjct: 724 SKE----KPEREKTP-------SEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENI 772
Query: 843 RKQERETFSSAEGTVDKDTTIMELR-------DRLPKKQQASASTDGVDKLSGKEQSFTS 895
+KQ ++T S++ ++ + R D P + + + V K + K++ S
Sbjct: 773 QKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLS 832
Query: 896 LEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKK 955
E +TK + K ++ K +D L + +S+ SED +
Sbjct: 833 AE-----KTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNL 887
Query: 956 KPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQI---------KNGTTDGEK 1006
KP + K ++ + S EKL + + K +K + K TT
Sbjct: 888 KPEEVVHK-----EKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPD 942
Query: 1007 KSKKIRDKTSKK--KDELSDYAEKSTGKG---DSCDSSEDKKSKNGAYGREKKRCKLLGK 1061
K K + S+K K ++ D + TG ++ SS K+ ++ + K K
Sbjct: 943 KEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYK 1002
Query: 1062 SS---------RKRQDCSSSDTEKYSMKE----DGCNSSDKRLKRIE-----LRERRNLS 1103
S RK D S + K+S K+ D S DK K ++ R +L
Sbjct: 1003 SDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLM 1062
Query: 1104 SKRNTKEIQSGSSSSDAEESSEDNKKKKQRT-SSKKKAVIVKEKKRNSLRTSTKRKQADI 1162
K+ ++ + S ++E ++ +K T S+ + + + KK + +++ +I
Sbjct: 1063 EKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEI 1122
Query: 1163 TSSSSSDI------EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSV 1216
S + D++N+ + D + +K T V C +
Sbjct: 1123 DSEPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQKDELRTCTADSKATAPAYK 1182
Query: 1217 P---VTVDDDDDDN-DPENRIAKKMLLEEIKANLSSDEDG-------------------- 1252
P V+ + + + D + + KKM ++ + ++ E
Sbjct: 1183 PGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVNIDSETVHRML 1242
Query: 1253 ----SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRL------ 1302
S +D ++ K T + GD ++ N +S R
Sbjct: 1243 LSAPSENDRVQKNLKNTAAEEHVAQGDATLEHSTNLDSSPSLSSVTVVPLRESYDPDVIP 1302
Query: 1303 LRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESG 1350
L K TV +G + T P +H + ++ SE + SD +E G
Sbjct: 1303 LFDKRTVLEGSTAS---TSPADHSALPNQSLTVRESEVLKTSDSKEGG 1347
Score = 70.1 bits (170), Expect = 3e-11
Identities = 107/539 (19%), Positives = 208/539 (38%), Gaps = 73/539 (13%)
Query: 1002 TDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGK 1061
T +++ R T + S+ A K + D+S DK+ + ++K G
Sbjct: 209 TSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGG 268
Query: 1062 SSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIEL-RERRNLSSKRNTKEIQSGSSSSDA 1120
+ S ++ E+ N + + I L ++ + SS++ K G D+
Sbjct: 269 EGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDS 328
Query: 1121 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGE 1180
E E K+KK++T KK K + ++ + K+ ++ S ++ ++ E
Sbjct: 329 NEKGERKKEKKEKTE-KKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVE 387
Query: 1181 GSSDE-----QKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1235
G+ ++ + +T+ V S HT D + D E
Sbjct: 388 GTKEDFSLIDSDVDGLTDITVSSVHTS------------------DLSSFEEDTE----- 424
Query: 1236 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSE---------- 1285
EE+ + S +E + D+ E+ K+ K + + + K+ ++
Sbjct: 425 ----EEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKY 480
Query: 1286 -SDSDSEESKKPRYR-------HRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVS 1337
SDSD E + + R + RLLR ++ E ++K + + + KG+ R V
Sbjct: 481 YSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVD 540
Query: 1338 SEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSS 1397
E+S + + + ++ + R KK L S K+KK R + + +
Sbjct: 541 LEESSTKSLEP-----KAARIKEVLKERKVLEKKVAL-----SKKRKKDSRNV----EEN 586
Query: 1398 SENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQN 1457
S+ K EE+ +E + E E+E+ E + + K R++ + + E +N
Sbjct: 587 SKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKN 646
Query: 1458 ALKEEEERRKR-----IAEREREREKLREVIEIEDASP--TKCPITTKLVLDEDEETKE 1509
K E E ++R I E +E R+V + S T+ P K L ++ K+
Sbjct: 647 ESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKK 705
Score = 55.8 bits (133), Expect = 5e-07
Identities = 132/645 (20%), Positives = 240/645 (37%), Gaps = 86/645 (13%)
Query: 846 ERETFSSAEGTVDKDTTIMELRDR-LPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAET 904
++E S GT +T R L + A G ++ SG+ S+ +R +A
Sbjct: 2470 QKEDKSPETGTAGGSSTASYSAGRGLEGNANSPAHLRGPEQTSGQTAKDPSVSIRYLAAV 2529
Query: 905 KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKK----GTEEKKKPSDF 960
+ +K VQ +++ FL +Q + SED+ K S G E K PS
Sbjct: 2530 NTGA--IKADDMPPVQGTVAE--HSFLPAEQ--QGSEDNLKTSTTKCITGQESKIAPS-- 2581
Query: 961 KKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKD 1020
+ T + C IK +G + ++K D S +K
Sbjct: 2582 ----------HTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQASAEKTGDDNSTRKS 2631
Query: 1021 --ELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEK-- 1076
E D + + + CD ++ N G L K++ K + S+ EK
Sbjct: 2632 FPEEGDIMVTVSSEENVCDIGNEESPLNVLGG-------LKLKANLKMEAYVPSEEEKNG 2684
Query: 1077 --YSMKEDGCNSSDKRLKRIE-----LRERRNLSSK--RNTKEIQSGS-SSSDAEESSED 1126
+ E C + ++ + E N+ + R +EI S S + + +D
Sbjct: 2685 EILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSESYNKGEISSGRKD 2744
Query: 1127 NKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQ 1186
N + S + V+E++R+ + KRKQ + SS D DD+ + + Q
Sbjct: 2745 NAEAISGHSVEADPKEVEEEERHMPKR--KRKQHYL---SSEDEPDDNPDVLDSRIETAQ 2799
Query: 1187 KIKPVTENLVLSSHTGFCQSSGD-EALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKAN 1245
+ P TE H ++S D E L K+ + N +R+ ++
Sbjct: 2800 RQCPETE-----PHDTKEENSRDLEELPKT-------SSETNSTTSRVMEE--------- 2838
Query: 1246 LSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRH 1305
DE SS+ TG++ E+N D+ K+Q E + K+ R R +
Sbjct: 2839 --KDEYSSSET--------TGEKPEQND-DDTIKSQ--EEDQPIIIKRKRGRPRKYPVET 2885
Query: 1306 KLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESE--DEQR 1363
L + D + ++ + + E ++ QE +S + E + R
Sbjct: 2886 TLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVR 2945
Query: 1364 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE 1423
R R K++ + + +++R+ V + + + S+EEEEE+EE+E
Sbjct: 2946 RRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRS 3005
Query: 1424 EEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKR 1468
E SK+ K ++ + RT Q ++E ++ +
Sbjct: 3006 TTRSEAQRSKTQLSPSIKRKREVSPPGARTRGQQRVEEAPVKKAK 3050
Score = 51.6 bits (122), Expect = 9e-06
Identities = 109/549 (19%), Positives = 203/549 (36%), Gaps = 132/549 (24%)
Query: 437 HQNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPE-----DIF 491
H +P E+Q + + K +E + P++T + SV P+ I
Sbjct: 2549 HSFLPAEQQGSEDNLKTSTTKCITGQESKIAPSHTM--IPPATYSVALLAPKCEQDLTIK 2606
Query: 492 ENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDN-------------RGGIKS 538
+ Q+S + GD +S + E + + +SS++N GG+K
Sbjct: 2607 NDYSGKWTDQASAEKTGDDNSTRKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKL 2666
Query: 539 KTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDN 598
K K+ E YV + K + P+ G K G+
Sbjct: 2667 KANLKM--EAYV-------PSEEEKNGEILAPPESLCGGKPSGI-----------AELQR 2706
Query: 599 EHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVK------EKQK 652
E L+ NE SL +E S R + + + + ++ N++ +V+ E+++
Sbjct: 2707 EPLLVNE-SLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPKEVEEEE 2765
Query: 653 LSVPVRKKDKR--NSSDSAIDNP---------KPNKLPKSKQSETVDQNSDSDEMLAILK 701
+P RK+ + +S D DNP + P+++ +T ++NS L+
Sbjct: 2766 RHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRD------LE 2819
Query: 702 EVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAK 761
E+ + S ++S T + + + + + G++ + +D DT K +
Sbjct: 2820 ELPKTSSETNS--------TTSRVMEEKDEYSSSETTGEKPEQ-----NDDDTIKSQEED 2866
Query: 762 SSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKG 821
II K+KR Y E ++K SK T ++ P++ + ++ +K+
Sbjct: 2867 QPIIIKRKR---GRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKET 2923
Query: 822 MDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTD 881
+ Q + S+DD E +K T + R R PK+
Sbjct: 2924 ANLQ-------ERSISNDDGE---------------EKIVTSVRRRGRKPKR-------- 2953
Query: 882 GVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSE 941
SL V AE+ E + K K V D + D K+ +SDE E
Sbjct: 2954 -------------SLTVSDDAESSEPER----KRQKSVSDPVED-----KKEQESDEEEE 2991
Query: 942 DDKKQSKKG 950
++++ G
Sbjct: 2992 EEEEDEPSG 3000
Score = 51.6 bits (122), Expect = 9e-06
Identities = 79/339 (23%), Positives = 139/339 (41%), Gaps = 55/339 (16%)
Query: 1205 QSSGDEALSKSVP------VTVDDDDDDNDPENRIAKKMLLE--EIKANLSSDEDGSSDD 1256
++ D + KS P VTV +++ D N + +L ++KANL + S++
Sbjct: 2621 KTGDDNSTRKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKLKANLKMEAYVPSEE 2680
Query: 1257 E--------PEE--GKKRTG-------------KQNEENPGDEEAKNQVNSESDSDSE-E 1292
E PE G K +G N EN G +++SES + E
Sbjct: 2681 EKNGEILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFR-TNEEIHSESYNKGEIS 2739
Query: 1293 SKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVS 1352
S + + H + E EE++ PK + R + +SSED D + V
Sbjct: 2740 SGRKDNAEAISGHSVEADPKEVEEEERHMPK-----RKRKQHYLSSEDEPDDN---PDVL 2791
Query: 1353 EEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKE 1412
+ E+ Q P T EEN R ++ K +SSE S + EEK+
Sbjct: 2792 DSRIETAQRQCPETEPHDTK--EENSRDLEELPK---------TSSETNSTTSRVMEEKD 2840
Query: 1413 EEEEEEEEEEEEEEDENDDSKSPGKGRKKI--RKILKDDKLRTETQNALKEEEERRKRIA 1470
E E E+ E++++D KS + + I RK + K ET +K++ + I
Sbjct: 2841 EYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIV 2900
Query: 1471 EREREREKLR-EVIEIEDASPTKCPITTKLVLDEDEETK 1508
E+ + +V++ ++++ + + + ++D E K
Sbjct: 2901 TVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEK 2939
Score = 49.7 bits (117), Expect = 4e-05
Identities = 71/338 (21%), Positives = 137/338 (40%), Gaps = 49/338 (14%)
Query: 734 GKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKI 793
G+ G++ + SG + + + K+++ Q S+ D + S+I
Sbjct: 2736 GEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRI 2795
Query: 794 GAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSA 853
T +++ P T+ D+ E+ + + KTS E +S + +E++ +SS+
Sbjct: 2796 ---ETAQRQCPETEPHDTKEENSRDLEELP-------KTSSETNSTTSRVMEEKDEYSSS 2845
Query: 854 EGTVDK-----DTTIMELRDRLP---KKQQASASTDGVD-KLSGKEQSFTSLEVRKVAET 904
E T +K D TI + P K+++ V+ L K+ S T + V ++
Sbjct: 2846 ETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQS 2905
Query: 905 KEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDE-----------------TSEDDKKQS 947
SK LK + +++ E+ + D +E T DD + S
Sbjct: 2906 PSSSK-LKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESS 2964
Query: 948 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK 1007
+ + +K SD +E + E SD E+ E +E P G ++ T ++
Sbjct: 2965 EPERKRQKSVSD------PVEDKKEQESDEEEEEEEEDE----PSG-ATTRSTTRSEAQR 3013
Query: 1008 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSK 1045
SK + K+K E+S ++ G+ + + KK+K
Sbjct: 3014 SKTQLSPSIKRKREVSPPGARTRGQ-QRVEEAPVKKAK 3050
Score = 46.6 bits (109), Expect = 3e-04
Identities = 52/289 (17%), Positives = 114/289 (39%), Gaps = 30/289 (10%)
Query: 1239 LEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRY 1298
+ E A L+ E+GS + P++ K T + P + N N
Sbjct: 155 VHEFLATLNHKEEGSGNTAPDDEKPDTSLITQGVPTPGPSANVANDAMS----------- 203
Query: 1299 RHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSES 1358
+ +T + E+ + + + + R +K+ S+ + D+ + SE++++
Sbjct: 204 ----ILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADK 259
Query: 1359 E----DEQRPRTRSAKKAE--------LEENQRSYKQKKK---RRRIKVQEDSSSENKSN 1403
E D +A K+E +EE + K+ + QE S +NKS
Sbjct: 260 EKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKST 319
Query: 1404 SEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEE 1463
+ E++ E+ E ++E++E+ ++ D + +K++ + + E+ E+
Sbjct: 320 DKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKN 379
Query: 1464 ERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLV 1512
+ + E +E L + T + T + +E+T+E +V
Sbjct: 380 SNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVV 428
Score = 43.5 bits (101), Expect = 0.003
Identities = 35/210 (16%), Positives = 93/210 (44%), Gaps = 7/210 (3%)
Query: 1224 DDDNDPENRIAKKMLLEEIKANLSSDE----DGSSDDEPEEGKKRTGKQNEENPGDEEAK 1279
DD+ + I + + AN+++D + + E R + E A
Sbjct: 175 DDEKPDTSLITQGVPTPGPSANVANDAMSILETITSLNQEASAARASTETSNAKTSERAS 234
Query: 1280 NQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSE 1339
++ S+ +D+ K+ + K T G G E K +E ++ ++ +
Sbjct: 235 KKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVE-EIKNY 293
Query: 1340 DSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSE 1399
E ++ ++++V + EQ+ ++ + + + N++ ++K+K+ + + + D S +
Sbjct: 294 TKEHNNLIL--LNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKK 351
Query: 1400 NKSNSEEEEEEKEEEEEEEEEEEEEEEDEN 1429
++ + ++E++ +E+E E + E++ N
Sbjct: 352 SEDTQKVKDEKQAKEKEVESLKLPSEKNSN 381
Score = 42.0 bits (97), Expect = 0.007
Identities = 53/279 (18%), Positives = 109/279 (39%), Gaps = 44/279 (15%)
Query: 1241 EIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRH 1300
EI + + + S E K ++ P + ++ ++SE + D
Sbjct: 2737 EISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPD------- 2789
Query: 1301 RLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1360
+L ++ + + E T+P + KE R+ ++ SE + + E+ S
Sbjct: 2790 -VLDSRIETAQRQCPE---TEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSS 2845
Query: 1361 E---QRPRTRSAKKAELEENQRSYKQKKKRRR---------IKVQEDSSS-------ENK 1401
E ++P + +E + K+KR R +K+++DS + E
Sbjct: 2846 ETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQS 2905
Query: 1402 SNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP------GKGRKKIRKILKDDKLRTET 1455
+S + + + +E +E +E NDD + +GRK R + D +
Sbjct: 2906 PSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESS- 2964
Query: 1456 QNALKEEEERRKRIA---EREREREKLREVIEIEDASPT 1491
+ E +R+K ++ E ++E+E E E E+ P+
Sbjct: 2965 ----EPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPS 2999
Score = 36.2 bits (82), Expect = 0.41
Identities = 46/205 (22%), Positives = 80/205 (39%), Gaps = 26/205 (12%)
Query: 1869 MDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGG 1928
++E I S +T LSSDD T++K K + +K S G +IK
Sbjct: 768 VEENIQKQSQQTK--LSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKT--------- 816
Query: 1929 EGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMV----L 1984
+ NV + N L E++KA S SS + + L+ +
Sbjct: 817 DENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKC 876
Query: 1985 LFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNID 2044
+ M + + +V + + L+E+ L L S+ KT +GK ++ ++
Sbjct: 877 DMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKT-----------QGKQVKVVE 925
Query: 2045 YYRLDGSTTAQSRKKWAEEFNDETN 2069
+G+T + K +E N E N
Sbjct: 926 TELQEGATKQATTPKPDKEKNTEEN 950
Score = 32.3 bits (72), Expect = 5.9
Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query: 1822 NSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETS 1881
NS + G K +DF ++ + + + + F+ED+ +E + SDS E
Sbjct: 379 NSNKAKTVEGTK--EDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEG 436
Query: 1882 MSLSSDDYTKKKKKGKKGKKDSSSSG 1907
++SDD K K+ K + SS G
Sbjct: 437 -EITSDDEEKNKQNKTKTQTSDSSEG 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,024,341
Number of Sequences: 37866
Number of extensions: 4811635
Number of successful extensions: 125823
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1279
Number of HSP's successfully gapped in prelim test: 1486
Number of HSP's that attempted gapping in prelim test: 33237
Number of HSP's gapped (non-prelim): 34808
length of query: 2454
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2335
effective length of database: 13,741,464
effective search space: 32086318440
effective search space used: 32086318440
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.