Search of human proteins with 113427525

Search of human proteins with 113427525

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113427525 PREDICTED: similar to hCG2037003 [Homo sapiens]
         (196 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113427525 PREDICTED: similar to hCG2037003 [Homo sapiens]          410   e-115
gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]         54   7e-08
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi...    48   5e-06
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi...    48   5e-06
gi|169162742 PREDICTED: hypothetical protein [Homo sapiens]            46   2e-05
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    46   2e-05
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    46   2e-05
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    46   2e-05
gi|119395716 forkhead box C1 [Homo sapiens]                            45   3e-05
gi|208431817 protein kinase-like protein SgK493 [Homo sapiens]         45   3e-05
gi|33286436 gametogenetin [Homo sapiens]                               45   4e-05
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            44   9e-05
gi|239753493 PREDICTED: hypothetical protein [Homo sapiens]            44   1e-04
gi|239748056 PREDICTED: hypothetical protein XP_002346522 [Homo ...    44   1e-04
gi|239741949 PREDICTED: hypothetical protein XP_002342360 [Homo ...    44   1e-04
gi|28269693 xylosyltransferase I [Homo sapiens]                        43   2e-04
gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]            43   2e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    43   2e-04
gi|23510413 sorting nexin 26 [Homo sapiens]                            43   2e-04
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    43   2e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    43   2e-04
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    43   2e-04
gi|31442420 shroom family member 1 [Homo sapiens]                      43   2e-04
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          42   4e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         42   4e-04
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]      42   4e-04
gi|113416171 PREDICTED: hypothetical protein [Homo sapiens]            41   6e-04
gi|169166294 PREDICTED: hypothetical protein [Homo sapiens]            41   6e-04
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap...    41   6e-04
gi|238859651 pleckstrin homology domain containing family A memb...    41   7e-04

>gi|113427525 PREDICTED: similar to hCG2037003 [Homo sapiens]
          Length = 196

 Score =  410 bits (1054), Expect = e-115
 Identities = 196/196 (100%), Positives = 196/196 (100%)

Query: 1   MSCPARIPCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGE 60
           MSCPARIPCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGE
Sbjct: 1   MSCPARIPCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGE 60

Query: 61  PGSRGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAW 120
           PGSRGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAW
Sbjct: 61  PGSRGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAW 120

Query: 121 GSLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPPCAGSSSQLTE 180
           GSLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPPCAGSSSQLTE
Sbjct: 121 GSLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPPCAGSSSQLTE 180

Query: 181 PSVIQQPSISAPNMPN 196
           PSVIQQPSISAPNMPN
Sbjct: 181 PSVIQQPSISAPNMPN 196


>gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]
          Length = 261

 Score = 54.3 bits (129), Expect = 7e-08
 Identities = 53/147 (36%), Positives = 61/147 (41%), Gaps = 20/147 (13%)

Query: 19  PGPETPPPAPAPT------------ARPRLRLPAPDWRARRADLTRRKGLRRGE-PGSRG 65
           PGP  P P PA              ARP  R   P   AR   L   +  RR   PG   
Sbjct: 51  PGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFP 110

Query: 66  LGEG-PAAARRPQV-QSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSL 123
           L  G P  A RP   +S     +G  AP  +RAQRPG SG     +    PG     G++
Sbjct: 111 LAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSG---GRSHPGGPGSPRGGGTV 167

Query: 124 RPGKRQQALESEAGGRASREARAAEVR 150
            PG R  A  +  GGR  R  RAAE R
Sbjct: 168 GPGDRGPA--AADGGRPQRTVRAAETR 192


>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
           sapiens]
          Length = 678

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 12/151 (7%)

Query: 18  PPGPETPPPA-PAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
           PP P  PPPA P+P A P  R       ARR+D  ++ G        RGL  G  A    
Sbjct: 102 PPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLS 161

Query: 77  QVQSIDTTPSG-----EGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPG----K 127
              S     +G      G+P  S   +P      PSL   P+PG  +A  +  P      
Sbjct: 162 NGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPS 221

Query: 128 RQQALESEAGGRASREARAA--EVRERIPGG 156
           ++Q + +      S E R A   V E IP G
Sbjct: 222 QRQCVSAATSTNDSFEIRPAPKPVMETIPLG 252


>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
           sapiens]
          Length = 650

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 46/151 (30%), Positives = 60/151 (39%), Gaps = 12/151 (7%)

Query: 18  PPGPETPPPA-PAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
           PP P  PPPA P+P A P  R       ARR+D  ++ G        RGL  G  A    
Sbjct: 102 PPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLS 161

Query: 77  QVQSIDTTPSG-----EGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPG----K 127
              S     +G      G+P  S   +P      PSL   P+PG  +A  +  P      
Sbjct: 162 NGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPS 221

Query: 128 RQQALESEAGGRASREARAA--EVRERIPGG 156
           ++Q + +      S E R A   V E IP G
Sbjct: 222 QRQCVSAATSTNDSFEIRPAPKPVMETIPLG 252


>gi|169162742 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 382

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 57/190 (30%), Positives = 71/190 (37%), Gaps = 26/190 (13%)

Query: 8   PCNKILTNDGPPGPETPPPAPAPTARPRLRLPAP-----DWRARRADLTRRKGLRRGEP- 61
           P    L  D PP P   PP P   A  + R PA       +    A L R  G R G+  
Sbjct: 49  PLFSSLLLDSPPWPPACPPTPPAKASVQPRHPARYISLLRYSEAAAPLPRGGGGRGGQDI 108

Query: 62  ------GSRGLGEGPAAARRPQ-VQSIDTTPSGEGAPS----FSRAQRPGRSGPSPSLAS 110
                 G    G+  A   RPQ + +    P+   A +      R +   R GP PSL +
Sbjct: 109 SLRARRGGTRTGDRGAELTRPQSLLARGLGPNWLAAAAANQGLGRGRDQPRPGPLPSLRA 168

Query: 111 DPAPGRGAAWGSLR-PGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTP 169
             A  RG A G +   G R  A     G R S+   A   R  +PG  +WC   R     
Sbjct: 169 QEAGRRGNAVGGVTGTGSRLHA----PGARGSQRPSARGPRGPLPGLAAWCYRPR----A 220

Query: 170 PCAGSSSQLT 179
            CA S  Q T
Sbjct: 221 RCAASEPQQT 230


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 50/160 (31%), Positives = 61/160 (38%), Gaps = 14/160 (8%)

Query: 17   GPPGPETPPPAPAPTAR-PRLRLPAPDWRARRADLTRRKGLR--RGEPGSRGLGEGPAAA 73
            GPPGP+ PP  P P+ R  +L     +      DL   +G R   G PG  G+   P   
Sbjct: 861  GPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEP 920

Query: 74   RRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPS--PSLASDPA-PGRGAAWGSLRPGKRQQ 130
             R  V S D  P   G P       PGR GP   P L   P  PGR    G  R G++  
Sbjct: 921  GRFGVNSSD-VPGPAGLPGV-----PGREGPPGFPGLPGPPGPPGREGPPG--RTGQKGS 972

Query: 131  ALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPP 170
              E+ A G    +        R   G +  PG      PP
Sbjct: 973  LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 1012



 Score = 34.7 bits (78), Expect = 0.053
 Identities = 39/123 (31%), Positives = 43/123 (34%), Gaps = 25/123 (20%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPA----------PDW-RARRADLTR-RKGL--RRGEPG 62
            G PGP  PP  P P   P   LPA          P W  AR AD  +   GL   +G+PG
Sbjct: 1001 GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPG 1060

Query: 63   SRGLGEGPAAARRPQVQSIDTTPSGEG-----APSFSRAQR-----PGRSG-PSPSLASD 111
              GL           V      P  EG      P   R  R     PG+ G   P L   
Sbjct: 1061 VPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGP 1120

Query: 112  PAP 114
            P P
Sbjct: 1121 PGP 1123



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 40/128 (31%), Positives = 46/128 (35%), Gaps = 28/128 (21%)

Query: 15   NDGPPGP-----ETPPPAPA---PTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGL 66
            N GPPGP     E  PP P    P    +L       +  R D   +KG  RGEPG  G 
Sbjct: 1290 NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGD-AGQKG-ERGEPGGGGF 1347

Query: 67   -------GEGPAAAR------RPQVQSI---DTTPSGEGAPSFSRAQRPGRSGP--SPSL 108
                     GP   R       P+ +SI      P  +G P      R G  GP   P  
Sbjct: 1348 FGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGP 1407

Query: 109  ASDPAPGR 116
             S P P R
Sbjct: 1408 PSFPGPHR 1415



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 31/109 (28%), Positives = 33/109 (30%), Gaps = 4/109 (3%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
           GPPG   PP +P     P L  P          L    G  +G PG  G    P     P
Sbjct: 764 GPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG-PQGPPGPPGRDGTPGRDGEP 822

Query: 77  QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRP 125
                D  P   G   F     PG  GP      DP  G     G   P
Sbjct: 823 GDPGEDGKPGDTGPQGFPGT--PGDVGPKGD-KGDPGVGERGPPGPQGP 868



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 32/118 (27%), Positives = 37/118 (31%), Gaps = 25/118 (21%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
            GPPGP   P  P P                           RG+PG  G  +GP      
Sbjct: 1357 GPPGPRGYPGIPGPKGES----------------------IRGQPGPPG-PQGPPGIGYE 1393

Query: 77   QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDP--APGRGAAWGSLRPGKRQQAL 132
              Q     P   G PSF    R   S P P     P   PG   A   +R    +QA+
Sbjct: 1394 GRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAM 1451



 Score = 28.9 bits (63), Expect = 2.9
 Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 13/73 (17%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPA--AAR 74
            GPPGP  PP  P P  R  + +P P                 G PG+ G   G    A R
Sbjct: 1400 GPPGPPGPPSFPGP-HRQTISVPGPPGPPGPP----------GPPGTMGASSGVRLWATR 1448

Query: 75   RPQVQSIDTTPSG 87
            +  +  +   P G
Sbjct: 1449 QAMLGQVHEVPEG 1461



 Score = 27.3 bits (59), Expect = 8.5
 Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 7/89 (7%)

Query: 41  PDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRPQVQSID--TTPSGEGAPSFSRAQR 98
           P  R +   L  +KG   G PG  G    P +   P    +    +P G   P+      
Sbjct: 744 PGGRVKEGGLKGQKG-EPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTV-- 800

Query: 99  PGRSGPSPSLASDPAPGRGAAWGSLRPGK 127
           PG  GP      D  PGR    G   PG+
Sbjct: 801 PGPQGPPGPPGRDGTPGRDGEPGD--PGE 827



 Score = 27.3 bits (59), Expect = 8.5
 Identities = 41/155 (26%), Positives = 54/155 (34%), Gaps = 40/155 (25%)

Query: 8    PCNKILTNDGPPGPETPPPAPAPT-ARPRLRLPAPDWRARRADL---------------- 50
            P  + ++  GPPGP  PP  P    A   +RL    W  R+A L                
Sbjct: 1413 PHRQTISVPGPPGPPGPPGPPGTMGASSGVRL----WATRQAMLGQVHEVPEGWLIFVAE 1468

Query: 51   -----------TRRKGLRRGEPGSRGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRP 99
                        R+  L    P  RG     AA + P VQ  D+ P          A RP
Sbjct: 1469 QEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTA-RP 1527

Query: 100  GRSG---PSPSLASDPAPGRGA----AWGSLRPGK 127
             R+     SP    +P P  GA    ++  LRP +
Sbjct: 1528 WRADDILASPPRLPEPQPYPGAPHHSSYVHLRPAR 1562


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 50/160 (31%), Positives = 61/160 (38%), Gaps = 14/160 (8%)

Query: 17  GPPGPETPPPAPAPTAR-PRLRLPAPDWRARRADLTRRKGLR--RGEPGSRGLGEGPAAA 73
           GPPGP+ PP  P P+ R  +L     +      DL   +G R   G PG  G+   P   
Sbjct: 446 GPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEP 505

Query: 74  RRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPS--PSLASDPA-PGRGAAWGSLRPGKRQQ 130
            R  V S D  P   G P       PGR GP   P L   P  PGR    G  R G++  
Sbjct: 506 GRFGVNSSD-VPGPAGLPGV-----PGREGPPGFPGLPGPPGPPGREGPPG--RTGQKGS 557

Query: 131 ALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPP 170
             E+ A G    +        R   G +  PG      PP
Sbjct: 558 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 597



 Score = 34.7 bits (78), Expect = 0.053
 Identities = 39/123 (31%), Positives = 43/123 (34%), Gaps = 25/123 (20%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPA----------PDW-RARRADLTR-RKGL--RRGEPG 62
           G PGP  PP  P P   P   LPA          P W  AR AD  +   GL   +G+PG
Sbjct: 586 GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPG 645

Query: 63  SRGLGEGPAAARRPQVQSIDTTPSGEG-----APSFSRAQR-----PGRSG-PSPSLASD 111
             GL           V      P  EG      P   R  R     PG+ G   P L   
Sbjct: 646 VPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGP 705

Query: 112 PAP 114
           P P
Sbjct: 706 PGP 708



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 40/128 (31%), Positives = 46/128 (35%), Gaps = 28/128 (21%)

Query: 15   NDGPPGP-----ETPPPAPA---PTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGL 66
            N GPPGP     E  PP P    P    +L       +  R D   +KG  RGEPG  G 
Sbjct: 875  NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGD-AGQKG-ERGEPGGGGF 932

Query: 67   -------GEGPAAAR------RPQVQSI---DTTPSGEGAPSFSRAQRPGRSGP--SPSL 108
                     GP   R       P+ +SI      P  +G P      R G  GP   P  
Sbjct: 933  FGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGP 992

Query: 109  ASDPAPGR 116
             S P P R
Sbjct: 993  PSFPGPHR 1000



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 31/109 (28%), Positives = 33/109 (30%), Gaps = 4/109 (3%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
           GPPG   PP +P     P L  P          L    G  +G PG  G    P     P
Sbjct: 349 GPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG-PQGPPGPPGRDGTPGRDGEP 407

Query: 77  QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRP 125
                D  P   G   F     PG  GP      DP  G     G   P
Sbjct: 408 GDPGEDGKPGDTGPQGFPGT--PGDVGPKGD-KGDPGVGERGPPGPQGP 453



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 32/118 (27%), Positives = 37/118 (31%), Gaps = 25/118 (21%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
            GPPGP   P  P P                           RG+PG  G  +GP      
Sbjct: 942  GPPGPRGYPGIPGPKGES----------------------IRGQPGPPG-PQGPPGIGYE 978

Query: 77   QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDP--APGRGAAWGSLRPGKRQQAL 132
              Q     P   G PSF    R   S P P     P   PG   A   +R    +QA+
Sbjct: 979  GRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAM 1036



 Score = 28.9 bits (63), Expect = 2.9
 Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 13/73 (17%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPA--AAR 74
            GPPGP  PP  P P  R  + +P P                 G PG+ G   G    A R
Sbjct: 985  GPPGPPGPPSFPGP-HRQTISVPGPPGPPGPP----------GPPGTMGASSGVRLWATR 1033

Query: 75   RPQVQSIDTTPSG 87
            +  +  +   P G
Sbjct: 1034 QAMLGQVHEVPEG 1046



 Score = 27.3 bits (59), Expect = 8.5
 Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 7/89 (7%)

Query: 41  PDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRPQVQSID--TTPSGEGAPSFSRAQR 98
           P  R +   L  +KG   G PG  G    P +   P    +    +P G   P+      
Sbjct: 329 PGGRVKEGGLKGQKG-EPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTV-- 385

Query: 99  PGRSGPSPSLASDPAPGRGAAWGSLRPGK 127
           PG  GP      D  PGR    G   PG+
Sbjct: 386 PGPQGPPGPPGRDGTPGRDGEPGD--PGE 412



 Score = 27.3 bits (59), Expect = 8.5
 Identities = 41/155 (26%), Positives = 54/155 (34%), Gaps = 40/155 (25%)

Query: 8    PCNKILTNDGPPGPETPPPAPAPT-ARPRLRLPAPDWRARRADL---------------- 50
            P  + ++  GPPGP  PP  P    A   +RL    W  R+A L                
Sbjct: 998  PHRQTISVPGPPGPPGPPGPPGTMGASSGVRL----WATRQAMLGQVHEVPEGWLIFVAE 1053

Query: 51   -----------TRRKGLRRGEPGSRGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRP 99
                        R+  L    P  RG     AA + P VQ  D+ P          A RP
Sbjct: 1054 QEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTA-RP 1112

Query: 100  GRSG---PSPSLASDPAPGRGA----AWGSLRPGK 127
             R+     SP    +P P  GA    ++  LRP +
Sbjct: 1113 WRADDILASPPRLPEPQPYPGAPHHSSYVHLRPAR 1147


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1516

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 50/160 (31%), Positives = 61/160 (38%), Gaps = 14/160 (8%)

Query: 17  GPPGPETPPPAPAPTAR-PRLRLPAPDWRARRADLTRRKGLR--RGEPGSRGLGEGPAAA 73
           GPPGP+ PP  P P+ R  +L     +      DL   +G R   G PG  G+   P   
Sbjct: 626 GPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEP 685

Query: 74  RRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPS--PSLASDPA-PGRGAAWGSLRPGKRQQ 130
            R  V S D  P   G P       PGR GP   P L   P  PGR    G  R G++  
Sbjct: 686 GRFGVNSSD-VPGPAGLPGV-----PGREGPPGFPGLPGPPGPPGREGPPG--RTGQKGS 737

Query: 131 ALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPP 170
             E+ A G    +        R   G +  PG      PP
Sbjct: 738 LGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP 777



 Score = 34.7 bits (78), Expect = 0.053
 Identities = 39/123 (31%), Positives = 43/123 (34%), Gaps = 25/123 (20%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPA----------PDW-RARRADLTR-RKGL--RRGEPG 62
           G PGP  PP  P P   P   LPA          P W  AR AD  +   GL   +G+PG
Sbjct: 766 GAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPG 825

Query: 63  SRGLGEGPAAARRPQVQSIDTTPSGEG-----APSFSRAQR-----PGRSG-PSPSLASD 111
             GL           V      P  EG      P   R  R     PG+ G   P L   
Sbjct: 826 VPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGP 885

Query: 112 PAP 114
           P P
Sbjct: 886 PGP 888



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 40/128 (31%), Positives = 46/128 (35%), Gaps = 28/128 (21%)

Query: 15   NDGPPGP-----ETPPPAPA---PTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGL 66
            N GPPGP     E  PP P    P    +L       +  R D   +KG  RGEPG  G 
Sbjct: 1055 NQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGD-AGQKG-ERGEPGGGGF 1112

Query: 67   -------GEGPAAAR------RPQVQSI---DTTPSGEGAPSFSRAQRPGRSGP--SPSL 108
                     GP   R       P+ +SI      P  +G P      R G  GP   P  
Sbjct: 1113 FGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGP 1172

Query: 109  ASDPAPGR 116
             S P P R
Sbjct: 1173 PSFPGPHR 1180



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 31/109 (28%), Positives = 33/109 (30%), Gaps = 4/109 (3%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
           GPPG   PP +P     P L  P          L    G  +G PG  G    P     P
Sbjct: 529 GPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPG-PQGPPGPPGRDGTPGRDGEP 587

Query: 77  QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRP 125
                D  P   G   F     PG  GP      DP  G     G   P
Sbjct: 588 GDPGEDGKPGDTGPQGFPGT--PGDVGPKGD-KGDPGVGERGPPGPQGP 633



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 32/118 (27%), Positives = 37/118 (31%), Gaps = 25/118 (21%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
            GPPGP   P  P P                           RG+PG  G  +GP      
Sbjct: 1122 GPPGPRGYPGIPGPKGES----------------------IRGQPGPPG-PQGPPGIGYE 1158

Query: 77   QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDP--APGRGAAWGSLRPGKRQQAL 132
              Q     P   G PSF    R   S P P     P   PG   A   +R    +QA+
Sbjct: 1159 GRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAM 1216



 Score = 28.9 bits (63), Expect = 2.9
 Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 13/73 (17%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPA--AAR 74
            GPPGP  PP  P P  R  + +P P                 G PG+ G   G    A R
Sbjct: 1165 GPPGPPGPPSFPGP-HRQTISVPGPPGPPGPP----------GPPGTMGASSGVRLWATR 1213

Query: 75   RPQVQSIDTTPSG 87
            +  +  +   P G
Sbjct: 1214 QAMLGQVHEVPEG 1226



 Score = 27.3 bits (59), Expect = 8.5
 Identities = 25/89 (28%), Positives = 32/89 (35%), Gaps = 7/89 (7%)

Query: 41  PDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRPQVQSID--TTPSGEGAPSFSRAQR 98
           P  R +   L  +KG   G PG  G    P +   P    +    +P G   P+      
Sbjct: 509 PGGRVKEGGLKGQKG-EPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTV-- 565

Query: 99  PGRSGPSPSLASDPAPGRGAAWGSLRPGK 127
           PG  GP      D  PGR    G   PG+
Sbjct: 566 PGPQGPPGPPGRDGTPGRDGEPGD--PGE 592



 Score = 27.3 bits (59), Expect = 8.5
 Identities = 41/155 (26%), Positives = 54/155 (34%), Gaps = 40/155 (25%)

Query: 8    PCNKILTNDGPPGPETPPPAPAPT-ARPRLRLPAPDWRARRADL---------------- 50
            P  + ++  GPPGP  PP  P    A   +RL    W  R+A L                
Sbjct: 1178 PHRQTISVPGPPGPPGPPGPPGTMGASSGVRL----WATRQAMLGQVHEVPEGWLIFVAE 1233

Query: 51   -----------TRRKGLRRGEPGSRGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRP 99
                        R+  L    P  RG     AA + P VQ  D+ P          A RP
Sbjct: 1234 QEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTA-RP 1292

Query: 100  GRSG---PSPSLASDPAPGRGA----AWGSLRPGK 127
             R+     SP    +P P  GA    ++  LRP +
Sbjct: 1293 WRADDILASPPRLPEPQPYPGAPHHSSYVHLRPAR 1327


>gi|119395716 forkhead box C1 [Homo sapiens]
          Length = 553

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 50/186 (26%), Positives = 72/186 (38%), Gaps = 21/186 (11%)

Query: 10  NKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEP----GSRG 65
           +++   + PP    PPPAP   A      P P    R  D+    G     P     +  
Sbjct: 187 DRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPP-PVRIQDIKTENGTCPSPPQPLSPAAA 245

Query: 66  LGEGPAAARRPQVQSIDTT----PSGEGAPSFSRAQRP-----GRSGPSPSLASDPAPGR 116
           LG G AAA  P+++S D++     SG   P    + RP       S P P   S P P  
Sbjct: 246 LGSGSAAA-VPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHH 304

Query: 117 GAAWG------SLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPP 170
              +       SLR   +  A E  +G  AS  A +          G++ PG+    + P
Sbjct: 305 SQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSP 364

Query: 171 CAGSSS 176
           C+ +SS
Sbjct: 365 CSQTSS 370


>gi|208431817 protein kinase-like protein SgK493 [Homo sapiens]
          Length = 493

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 36/107 (33%), Positives = 44/107 (41%), Gaps = 21/107 (19%)

Query: 19  PGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPG--SRGLGEGPAAARRP 76
           PG E P P  +P   P    P P  R  R +L R+   R  E    SRG G GP A R  
Sbjct: 28  PGSEPPRPGQSPEPSPA---PGPGRRGGRGELARQIRARYEEVQRYSRG-GPGPGAGRPE 83

Query: 77  QVQSIDTTPSG---------------EGAPSFSRAQRPGRSGPSPSL 108
           + + +D  P G               +GAP +  A  PG  GP P L
Sbjct: 84  RRRLMDLAPGGPGLPRPRPPWARPLSDGAPGWPPAPGPGSPGPGPRL 130



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 30/103 (29%), Positives = 35/103 (33%), Gaps = 12/103 (11%)

Query: 93  FSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEAGGRASREARAAEVRER 152
           F+    P R G SP  +  P PGR    G L    RQ     E   R SR          
Sbjct: 26  FAPGSEPPRPGQSPEPSPAPGPGRRGGRGEL---ARQIRARYEEVQRYSRGG-------- 74

Query: 153 IPGGGSWCPGRRDWLTPPCAGSSSQLTEPSVIQQPSISAPNMP 195
            PG G+  P RR  +     G       P   +  S  AP  P
Sbjct: 75  -PGPGAGRPERRRLMDLAPGGPGLPRPRPPWARPLSDGAPGWP 116


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 16/155 (10%)

Query: 8   PCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLG 67
           P N      GPPG +  PP P PT  P L+ PA           +   L    P + GLG
Sbjct: 421 PTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPA----------LQPTPLPVAPPLTPGLG 470

Query: 68  EGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGK 127
              +A       ++    + + AP+ S A  P  + PSP + S PAP         R  K
Sbjct: 471 HKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPV-SAPAPAAAPIKTRTRRNK 529

Query: 128 RQQALESEA-----GGRASREARAAEVRERIPGGG 157
             +A           G   RE   A V +   GGG
Sbjct: 530 GSRAARGATRKDGLHGDGPRERATATVPDSSGGGG 564



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 12/86 (13%)

Query: 13  LTNDGPPGPETPPPAPAPTA---RPRLRLPAPDWRARRADLTRRKGLR--RGEPGSRGL- 66
           L  D  P P    PAPAPT     P +  PAP     +    R KG R  RG     GL 
Sbjct: 488 LAADQAPAPS---PAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLH 544

Query: 67  GEGPAAARRPQVQSIDTTPSGEGAPS 92
           G+GP   R     ++  +  G G  S
Sbjct: 545 GDGP---RERATATVPDSSGGGGGGS 567



 Score = 28.9 bits (63), Expect = 2.9
 Identities = 50/197 (25%), Positives = 73/197 (37%), Gaps = 30/197 (15%)

Query: 4   PARIPCNKILTNDGPPGPE------TPPPAPAPTARP---RLRLPA--PDWRARRADLTR 52
           P+ +P      +   P PE       PPPAPA T  P   + + PA  P  R RR     
Sbjct: 70  PSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEAS 129

Query: 53  RKGLRRGEPGSRGLGEGPAAARRPQVQSIDTTP-----------SGEGAPSFSRAQRPGR 101
            +G  +G+P S    + P   R+  V+  DT P           + +  P     ++P  
Sbjct: 130 HRG--QGDPPSLRPLKPPPPPRQLSVK--DTVPRAPSQFPPPLETWKPPPPLPSERQPAD 185

Query: 102 SGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCP 161
              +P+LA+  +P   +  G    G+        A   A  E   A+  +   G    C 
Sbjct: 186 RRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAG-EGEMAQPADSESGLSLLCK 244

Query: 162 ---GRRDWLTPPCAGSS 175
                R  L PP A SS
Sbjct: 245 ITFKSRPSLAPPAASSS 261


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 43/146 (29%), Positives = 54/146 (36%), Gaps = 11/146 (7%)

Query: 19  PGPETPPPAPAPTARPRLRLPAPDWRARR------ADLTRRKGLRRGEPGSRGLGEGPAA 72
           PGP+ PP  PAP A       A    A        A+   R      E G  G   GP A
Sbjct: 12  PGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEA 71

Query: 73  ARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQAL 132
             R    +   T + EGAP  +   + G            +PGRGA  G  R G+ Q+  
Sbjct: 72  EARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQ-GEPR-GEAQREP 129

Query: 133 ESEAGGRASREARAAEVRERIPGGGS 158
           E  A      E   AE R  +P G +
Sbjct: 130 EDSAAPERQEE---AEQRPEVPEGSA 152


>gi|239753493 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 254

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 51/176 (28%), Positives = 67/176 (38%), Gaps = 28/176 (15%)

Query: 4   PARIPCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGS 63
           PA    + +L N      E PPPAPAP    RLR P P+           +G+    PGS
Sbjct: 43  PASSHESHVLDNAPAAAREPPPPAPAPRCL-RLRPPFPE-----------EGV-AARPGS 89

Query: 64  RGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSL 123
             +G G   AR+ +     T   GEG    + A  P  +   P+L  D   GR +  G  
Sbjct: 90  CPVGWG---ARKLE----GTGVLGEGEKLVTWANLPQGNEELPALGRDRGAGRMSPHGKR 142

Query: 124 RPGKRQQALE--------SEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPPC 171
             G+ Q  L          + GG   R  R+ E+R      G   PG      P C
Sbjct: 143 ADGQAQGQLRLPPSTPRAPDRGGCEPRAPRSQELRSWAQPAGGRAPGCAAPWVPQC 198


>gi|239748056 PREDICTED: hypothetical protein XP_002346522 [Homo
           sapiens]
          Length = 254

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 51/176 (28%), Positives = 67/176 (38%), Gaps = 28/176 (15%)

Query: 4   PARIPCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGS 63
           PA    + +L N      E PPPAPAP    RLR P P+           +G+    PGS
Sbjct: 43  PASSHESHVLDNAPAAAREPPPPAPAPRCL-RLRPPFPE-----------EGV-AARPGS 89

Query: 64  RGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSL 123
             +G G   AR+ +     T   GEG    + A  P  +   P+L  D   GR +  G  
Sbjct: 90  CPVGWG---ARKLE----GTGVLGEGEKLVTWANLPQGNEELPALGRDRGAGRMSPHGKR 142

Query: 124 RPGKRQQALE--------SEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPPC 171
             G+ Q  L          + GG   R  R+ E+R      G   PG      P C
Sbjct: 143 ADGQAQGQLRLPPSTPRAPDRGGCEPRAPRSQELRSWAQPAGGRAPGCAAPWVPQC 198


>gi|239741949 PREDICTED: hypothetical protein XP_002342360 [Homo
           sapiens]
          Length = 254

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 51/176 (28%), Positives = 67/176 (38%), Gaps = 28/176 (15%)

Query: 4   PARIPCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGS 63
           PA    + +L N      E PPPAPAP    RLR P P+           +G+    PGS
Sbjct: 43  PASSHESHVLDNAPAAAREPPPPAPAPRCL-RLRPPFPE-----------EGV-AARPGS 89

Query: 64  RGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSL 123
             +G G   AR+ +     T   GEG    + A  P  +   P+L  D   GR +  G  
Sbjct: 90  CPVGWG---ARKLE----GTGVLGEGEKLVTWANLPQGNEELPALGRDRGAGRMSPHGKR 142

Query: 124 RPGKRQQALE--------SEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPPC 171
             G+ Q  L          + GG   R  R+ E+R      G   PG      P C
Sbjct: 143 ADGQAQGQLRLPPSTPRAPDRGGCEPRAPRSQELRSWAQPAGGRAPGCAAPWVPQC 198


>gi|28269693 xylosyltransferase I [Homo sapiens]
          Length = 959

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 35/95 (36%), Positives = 37/95 (38%), Gaps = 22/95 (23%)

Query: 20  GPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRPQVQ 79
           G E PPPAPAP  R R  LPA    AR            G  G  G G GP A  R    
Sbjct: 53  GGEQPPPAPAPR-RERRDLPAEPAAARGGG---------GGGGGGGGGRGPQARARG--- 99

Query: 80  SIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAP 114
                    G P   R Q+P   G  P+ A DP P
Sbjct: 100 ---------GGPGEPRGQQPASRGALPARALDPHP 125


>gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 370

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 48/149 (32%), Positives = 60/149 (40%), Gaps = 22/149 (14%)

Query: 19  PGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGE---GPAAARR 75
           P P  PPPAP     P    PA         LT  +   R    +RG GE   GP    R
Sbjct: 224 PAPCLPPPAPPAARTPSAHSPA----HTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGR 279

Query: 76  PQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESE 135
           P+ +  D+  S    P+      P    PS + A  P   RGA   + R G+R+Q     
Sbjct: 280 PENE--DSLASQTSPPA------PPAPVPSTARARSPGARRGARELAPRAGRRRQ----- 326

Query: 136 AGGRASREARA-AEVRERIPG-GGSWCPG 162
             GR S   RA  E R+R P   G+W  G
Sbjct: 327 PSGRTSWRRRARREQRDREPAVCGAWPRG 355


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 61/215 (28%), Positives = 81/215 (37%), Gaps = 41/215 (19%)

Query: 14  TNDGP---PGPETPPPAPAPTARPRLRLPAPDW--RARRADLTRRK----GLRRGEPGSR 64
           T+ GP   PG  +    P P  +  LR+ A +   R +  +  +R     G RR   G  
Sbjct: 100 TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 159

Query: 65  GLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLAS-------DPAPG-- 115
                PA ARR +      T  G   P+ S   RP   GP  S++S       +P+P   
Sbjct: 160 PGTPSPAMARRSRAAG---TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 216

Query: 116 -RGAAWGSL-RPGKRQQALESEAGGRASREARAAEVRERIPGGGSW-------------- 159
            R +A G L RP  R  +  +      +R   +A    R P   S               
Sbjct: 217 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 276

Query: 160 CPGRRDWLTPPCAG--SSSQLTEPSVIQQPSISAP 192
            P R+D    P  G  SSS L  PS    PS SAP
Sbjct: 277 TPPRKD--AAPALGPLSSSPLATPSPSAPPSPSAP 309



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 46/185 (24%), Positives = 60/185 (32%), Gaps = 17/185 (9%)

Query: 4   PARIPCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPG- 62
           P ++P +   +    P    PP AP P A P L+L  P  +A  A  T         P  
Sbjct: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 498

Query: 63  ---------SRGLGEGPAAARRPQVQSI------DTTPSGEGAPSFSRAQRPGRSGPSPS 107
                    S  L   P A   PQ   +         PS   +P+    +RP   GP  S
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 558

Query: 108 LASDPAPGRGAAWGSLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWL 167
           + S P      A G   P  R  +        A   + A    E + G  S   G     
Sbjct: 559 V-SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 617

Query: 168 TPPCA 172
            PP A
Sbjct: 618 PPPDA 622



 Score = 35.4 bits (80), Expect = 0.031
 Identities = 51/196 (26%), Positives = 68/196 (34%), Gaps = 33/196 (16%)

Query: 5   ARIPCNKI--LTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPG 62
           AR P  +   L    PPG   PPP   P A   LR+        R  L  R G       
Sbjct: 14  ARTPAARAPGLLTPRPPGSPRPPPPVTPAA---LRVLGAAGAVGRKPLAERAG------- 63

Query: 63  SRGLGEGPAAARRPQVQSIDTT-PSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWG 121
             G+G        P+     T+ P   G        R  R+ P+ + +  P    G A G
Sbjct: 64  --GIGGATIPESAPRAGPTRTSRPPASG--------RGERAPPAKNTSPGPVSSPGRASG 113

Query: 122 SLRPGK------RQQALESEAGGRAS----REARAAEVRERIPGGGSWCPGRRDWLTPPC 171
           + RPG       R  A E+ A G+A+    R A +A  R    G     P          
Sbjct: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173

Query: 172 AGSSSQLTEPSVIQQP 187
           AG+   L  P+   +P
Sbjct: 174 AGTEVGLPRPAPSARP 189



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 33/115 (28%), Positives = 43/115 (37%), Gaps = 28/115 (24%)

Query: 19  PGPET------------PPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRG-EPGSRG 65
           PGP+T            P P P P+  P   L  PD     +  T      RG + G  G
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612

Query: 66  LGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAW 120
              G AA+  P  +     P+     ++SR       GP+P LA   APG    W
Sbjct: 613 ---GAAASPPPDAELAACHPA-----AWSR-------GPAPPLAFRGAPGAPLPW 652


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 58/221 (26%), Positives = 81/221 (36%), Gaps = 38/221 (17%)

Query: 9   CNKILTNDGPPGPETPPPAPAP---TARPRLRLPAPDWRARR---ADLTRRKGLRRGEPG 62
           C+K+    GP GP+   P P P     RP    P P     R     L  R      +  
Sbjct: 696 CSKLRGAQGPLGPDMESPLPPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQS 755

Query: 63  SRGLGEGPAAARRPQVQSIDTT-------PSGEGAPSFSRAQRPGR--SGPSPSLASDPA 113
            +  G  P A++ P  +S+           SG G P  S A  PG    GP P L    +
Sbjct: 756 QQECGGTPPASQSPFHRSLSLEVGGEPLGTSGSGPPPNSLA-HPGAWVPGPPPYLPRQQS 814

Query: 114 PG--------RGAAWGSLR-PGKRQQALESEAGGRASREARA---AEVRERIPGGGSWCP 161
            G         G +   LR P +    L +  GGR + EA A     V  ++P  G + P
Sbjct: 815 DGSLLRSQRPMGTSRRGLRGPAQVSAQLRAGGGGRDAPEAAAQSPCSVPSQVPTPGFFSP 874

Query: 162 GRRDWLTP----------PCAGSSSQLTEPSVIQQPSISAP 192
             R+ L P          P    S Q + P+ + + S+  P
Sbjct: 875 APRECLPPFLGVPKPGLYPLGPPSFQPSSPAPVWRSSLGPP 915


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 48/155 (30%), Positives = 58/155 (37%), Gaps = 29/155 (18%)

Query: 17  GPPGPETP------PPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGP 70
           GPP P  P      PP P P A P    PAP     RA+    +    G P  R L    
Sbjct: 21  GPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGR-LRSRD 79

Query: 71  AAARRPQVQSIDTT----PSGE---GAPSFSRAQRPGRS-GPSPSL-----ASDPAPGRG 117
           ++  RP      +T    P+GE   G P  S A   G + GP  S      AS PAPG  
Sbjct: 80  SSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPG-- 137

Query: 118 AAWGSLRPGKRQQALESEAGGRASREARAAEVRER 152
                  PG  ++A   EAG         A   +R
Sbjct: 138 -------PGPAEEAGSEEAGPAGEPRGSQASFMQR 165



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 42/118 (35%), Positives = 49/118 (41%), Gaps = 22/118 (18%)

Query: 17  GPPGPETPPPAPAPTARPRLR----LPA-----PDWRARRADLTRRKGLRRGEPGSRGLG 67
           GPP P +PP APA    PR      LPA     P   ARR     R  L   +P      
Sbjct: 773 GPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRP-LSASQPSLPHGA 831

Query: 68  EGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRP 125
            GPAA+ RP   S   TP     P+ +RA     + PSP      +PG   A G L P
Sbjct: 832 PGPAASTRPASSS---TPRLGPTPA-ARA-----AAPSPDRRDSASPG---AAGGLDP 877



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 40/121 (33%), Positives = 47/121 (38%), Gaps = 13/121 (10%)

Query: 24  PPPAPAP-TARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAAR-----RPQ 77
           PPP PAP  A P    PA    A  +    R     G P +   G    A R     RP 
Sbjct: 761 PPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPL 820

Query: 78  VQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEAG 137
             S  + P   GAP  + + RP  S  +P L   PA  R AA     P +R  A    AG
Sbjct: 821 SASQPSLP--HGAPGPAASTRPA-SSSTPRLGPTPA-ARAAA---PSPDRRDSASPGAAG 873

Query: 138 G 138
           G
Sbjct: 874 G 874



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 35/121 (28%), Positives = 44/121 (36%), Gaps = 9/121 (7%)

Query: 62  GSRGLGEGPAAARRPQVQSIDTTP--SGEGAPSFSRAQRPGRSG--PSPSLASDPAPGRG 117
           GS  L   P     P   S    P  S  GAP+  RA R    G  P+  LA    P R 
Sbjct: 753 GSPRLVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARR 812

Query: 118 AAWGSLRPGKRQQALESEAGGRASREARAAEVRERI-----PGGGSWCPGRRDWLTPPCA 172
            +  S      Q +L   A G A+    A+    R+         +  P RRD  +P  A
Sbjct: 813 LSRASRPLSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAA 872

Query: 173 G 173
           G
Sbjct: 873 G 873


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 49/154 (31%), Positives = 56/154 (36%), Gaps = 22/154 (14%)

Query: 15  NDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLR-----RGEPGSRGLGEG 69
           NDG PGP  PP    P   P    P        A  T  +G       RGEPG+ G   G
Sbjct: 346 NDGQPGPAGPPGPVGPAGGP--GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG-SPG 402

Query: 70  PA-AARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKR 128
           PA A+  P    I       GAP  + A  PG  GP         PG   A G L P K 
Sbjct: 403 PAGASGNPGTDGIPGAKGSAGAPGIAGA--PGFPGPR------GPPGPQGATGPLGP-KG 453

Query: 129 QQALESEAGGRASREARAAEVRERIPGGGSWCPG 162
           Q      AG +  +  +     E  P G    PG
Sbjct: 454 QTGEPGIAGFKGEQGPKG----EPGPAGPQGAPG 483



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 40/146 (27%), Positives = 52/146 (35%), Gaps = 16/146 (10%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
           GP GP  PP  P          P  D  A +      K   RG PG +G    P     P
Sbjct: 237 GPMGPRGPPGPPGK--------PGDDGEAGKPG----KAGERGPPGPQGARGFPGTPGLP 284

Query: 77  QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEA 136
            V+     P  +GA     A  PG  G S S   + +PG     G   PG+R +   + A
Sbjct: 285 GVKGHRGYPGLDGAK--GEAGAPGVKGESGSPGENGSPGPMGPRG--LPGERGRTGPAGA 340

Query: 137 GGRASREARAAEVRERIPGGGSWCPG 162
            G    + +        P G +  PG
Sbjct: 341 AGARGNDGQPGPAGPPGPVGPAGGPG 366



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 35/119 (29%), Positives = 41/119 (34%), Gaps = 6/119 (5%)

Query: 15  NDGPPGPETPPPAPAPTARPRLRLPAP-DWRARRADLTRRKGLRRGEPGSRGLGEGPAAA 73
           N GPPGP  PP  P        ++    D +A  A L    G+ +G  G  G    P  A
Sbjct: 160 NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL----GVMQGPMGPMGPRGPPGPA 215

Query: 74  RRPQVQSIDTTPSGEGAPSFSRAQRP-GRSGPSPSLASDPAPGRGAAWGSLRPGKRQQA 131
             P  Q     P   G P  S    P G  GP      D   G+    G   P   Q A
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 274



 Score = 37.0 bits (84), Expect = 0.011
 Identities = 39/140 (27%), Positives = 47/140 (33%), Gaps = 14/140 (10%)

Query: 17   GPPGPETPPPAPAPTARP-RLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARR 75
            GPPGP  PP    P   P R   P  D    R      KG  RGE G+ G    P     
Sbjct: 1017 GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG-DRGETGAVGAPGAPGPPGS 1075

Query: 76   PQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESE 135
            P          G   P+  +  R       P   S PA  RG        G + +A   E
Sbjct: 1076 P----------GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA--GE 1123

Query: 136  AGGRASREARAAEVRERIPG 155
             G R  +  R     + +PG
Sbjct: 1124 PGERGLKGHRGFTGLQGLPG 1143



 Score = 34.3 bits (77), Expect = 0.070
 Identities = 48/181 (26%), Positives = 61/181 (33%), Gaps = 16/181 (8%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRAR-RADLTRRKGL--RRGEPGSRGLGEGPAAA 73
            G PGP+ P  AP P     +  P     A+     T   G   R G PGS G   GP   
Sbjct: 861  GAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG-NPGPPGP 919

Query: 74   RRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALE 133
              P  +       G+  P   RA  PG  GP+        PG     G+  P   Q    
Sbjct: 920  PGPSGKDGPKGARGDSGPP-GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ---- 974

Query: 134  SEAGGRASREARAAEVRERIPG--GGSWCPGRRDWLTPPCAGSSSQLTEPSVIQQPSISA 191
              AG R              PG  G S  PG++        G+S     P  +  P ++ 
Sbjct: 975  GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG-----APGASGDRGPPGPVGPPGLTG 1029

Query: 192  P 192
            P
Sbjct: 1030 P 1030



 Score = 32.0 bits (71), Expect = 0.35
 Identities = 39/140 (27%), Positives = 48/140 (34%), Gaps = 38/140 (27%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGL-------RRGEPGSRGL--- 66
           G PGP  P  AP P               +R       G+        RG PG+RG    
Sbjct: 471 GEPGPAGPQGAPGPAGE----------EGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQ 520

Query: 67  ----------GE-GPAAARRPQVQSIDTTPSGEGAPSFSRAQ----RPGRSGPSPSLASD 111
                     GE GP+    P+  + D  P   G P    A+    RPG +GP   +   
Sbjct: 521 DGLAGPKGAPGERGPSGLAGPKGANGD--PGRPGEPGLPGARGLTGRPGDAGPQGKVGPS 578

Query: 112 PAPGRGAAWGSLRP-GKRQQ 130
            APG     G   P G R Q
Sbjct: 579 GAPGEDGRPGPPGPQGARGQ 598



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 36/116 (31%), Positives = 43/116 (37%), Gaps = 12/116 (10%)

Query: 15   NDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGL--RRGEPGSRGLGEGPAA 72
            N GPPGP  P P+     +       P  RA    L    G    +GEPG     +GP+ 
Sbjct: 913  NPGPPGP--PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD----DGPSG 966

Query: 73   ARRPQ-VQSIDTTPSGEGAPSFSRAQR--PGRSGPSPSLASDPAPGRGAAWGSLRP 125
            A  P   Q +       G P   R +R  PG  GPS       APG     G   P
Sbjct: 967  AEGPPGPQGLAGQRGIVGLPG-QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 49/154 (31%), Positives = 56/154 (36%), Gaps = 22/154 (14%)

Query: 15  NDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLR-----RGEPGSRGLGEG 69
           NDG PGP  PP    P   P    P        A  T  +G       RGEPG+ G   G
Sbjct: 277 NDGQPGPAGPPGPVGPAGGP--GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG-SPG 333

Query: 70  PA-AARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKR 128
           PA A+  P    I       GAP  + A  PG  GP         PG   A G L P K 
Sbjct: 334 PAGASGNPGTDGIPGAKGSAGAPGIAGA--PGFPGPR------GPPGPQGATGPLGP-KG 384

Query: 129 QQALESEAGGRASREARAAEVRERIPGGGSWCPG 162
           Q      AG +  +  +     E  P G    PG
Sbjct: 385 QTGEPGIAGFKGEQGPKG----EPGPAGPQGAPG 414



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 40/146 (27%), Positives = 52/146 (35%), Gaps = 16/146 (10%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
           GP GP  PP  P          P  D  A +      K   RG PG +G    P     P
Sbjct: 168 GPMGPRGPPGPPGK--------PGDDGEAGKPG----KAGERGPPGPQGARGFPGTPGLP 215

Query: 77  QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEA 136
            V+     P  +GA     A  PG  G S S   + +PG     G   PG+R +   + A
Sbjct: 216 GVKGHRGYPGLDGAK--GEAGAPGVKGESGSPGENGSPGPMGPRG--LPGERGRTGPAGA 271

Query: 137 GGRASREARAAEVRERIPGGGSWCPG 162
            G    + +        P G +  PG
Sbjct: 272 AGARGNDGQPGPAGPPGPVGPAGGPG 297



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 35/119 (29%), Positives = 41/119 (34%), Gaps = 6/119 (5%)

Query: 15  NDGPPGPETPPPAPAPTARPRLRLPAP-DWRARRADLTRRKGLRRGEPGSRGLGEGPAAA 73
           N GPPGP  PP  P        ++    D +A  A L    G+ +G  G  G    P  A
Sbjct: 91  NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL----GVMQGPMGPMGPRGPPGPA 146

Query: 74  RRPQVQSIDTTPSGEGAPSFSRAQRP-GRSGPSPSLASDPAPGRGAAWGSLRPGKRQQA 131
             P  Q     P   G P  S    P G  GP      D   G+    G   P   Q A
Sbjct: 147 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 205



 Score = 37.0 bits (84), Expect = 0.011
 Identities = 39/140 (27%), Positives = 47/140 (33%), Gaps = 14/140 (10%)

Query: 17   GPPGPETPPPAPAPTARP-RLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARR 75
            GPPGP  PP    P   P R   P  D    R      KG  RGE G+ G    P     
Sbjct: 948  GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG-DRGETGAVGAPGAPGPPGS 1006

Query: 76   PQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESE 135
            P          G   P+  +  R       P   S PA  RG        G + +A   E
Sbjct: 1007 P----------GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA--GE 1054

Query: 136  AGGRASREARAAEVRERIPG 155
             G R  +  R     + +PG
Sbjct: 1055 PGERGLKGHRGFTGLQGLPG 1074



 Score = 34.3 bits (77), Expect = 0.070
 Identities = 48/181 (26%), Positives = 61/181 (33%), Gaps = 16/181 (8%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPAPDWRAR-RADLTRRKGL--RRGEPGSRGLGEGPAAA 73
           G PGP+ P  AP P     +  P     A+     T   G   R G PGS G   GP   
Sbjct: 792 GAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG-NPGPPGP 850

Query: 74  RRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALE 133
             P  +       G+  P   RA  PG  GP+        PG     G+  P   Q    
Sbjct: 851 PGPSGKDGPKGARGDSGPP-GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQ---- 905

Query: 134 SEAGGRASREARAAEVRERIPG--GGSWCPGRRDWLTPPCAGSSSQLTEPSVIQQPSISA 191
             AG R              PG  G S  PG++        G+S     P  +  P ++ 
Sbjct: 906 GLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG-----APGASGDRGPPGPVGPPGLTG 960

Query: 192 P 192
           P
Sbjct: 961 P 961



 Score = 32.0 bits (71), Expect = 0.35
 Identities = 39/140 (27%), Positives = 48/140 (34%), Gaps = 38/140 (27%)

Query: 17  GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGL-------RRGEPGSRGL--- 66
           G PGP  P  AP P               +R       G+        RG PG+RG    
Sbjct: 402 GEPGPAGPQGAPGPAGE----------EGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQ 451

Query: 67  ----------GE-GPAAARRPQVQSIDTTPSGEGAPSFSRAQ----RPGRSGPSPSLASD 111
                     GE GP+    P+  + D  P   G P    A+    RPG +GP   +   
Sbjct: 452 DGLAGPKGAPGERGPSGLAGPKGANGD--PGRPGEPGLPGARGLTGRPGDAGPQGKVGPS 509

Query: 112 PAPGRGAAWGSLRP-GKRQQ 130
            APG     G   P G R Q
Sbjct: 510 GAPGEDGRPGPPGPQGARGQ 529



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 36/116 (31%), Positives = 43/116 (37%), Gaps = 12/116 (10%)

Query: 15  NDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGL--RRGEPGSRGLGEGPAA 72
           N GPPGP  P P+     +       P  RA    L    G    +GEPG     +GP+ 
Sbjct: 844 NPGPPGP--PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD----DGPSG 897

Query: 73  ARRPQ-VQSIDTTPSGEGAPSFSRAQR--PGRSGPSPSLASDPAPGRGAAWGSLRP 125
           A  P   Q +       G P   R +R  PG  GPS       APG     G   P
Sbjct: 898 AEGPPGPQGLAGQRGIVGLPG-QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952


>gi|31442420 shroom family member 1 [Homo sapiens]
          Length = 847

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 48/168 (28%), Positives = 61/168 (36%), Gaps = 33/168 (19%)

Query: 24  PPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGS-RGLGEGPAAARRPQVQSID 82
           PP  PA  A  R RL     R  R    +RK LR   P   R        A  P+  S+ 
Sbjct: 131 PPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASL- 189

Query: 83  TTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEAGGRASR 142
           + P GEG P+ SRA  PG +G        P   +   W    PGK  +       GR   
Sbjct: 190 SHPGGEGEPARSRAPAPGTAG------RGPLANQQRKWCFSEPGKLDRV------GR--- 234

Query: 143 EARAAEVRERIPGGGSWCPGRRDWLTPPCAGSSSQLTEPSVIQQPSIS 190
                       GGG      R+ L   C+ S     EP   Q P+++
Sbjct: 235 ------------GGGP----ARECLGEACSSSGLPGPEPLEFQHPALA 266


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 53/181 (29%), Positives = 64/181 (35%), Gaps = 33/181 (18%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
            GPPGP  P   P P   P L  P    +  + D        RGE G  G GEG  A   P
Sbjct: 1374 GPPGPRGPLGDPGPRGPPGL--PGTAMKGDKGD--------RGERGPPGPGEGGIAPGEP 1423

Query: 77   QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEA 136
             +  +  +P  +G         PG+ G     + D APG     GS  PG        E 
Sbjct: 1424 GLPGLPGSPGPQGP-----VGPPGKKGEKGD-SEDGAPGLPGQPGS--PG--------EQ 1467

Query: 137  GGRASREARAAEVRERIPG--GGSWCPGRRDWLTPPCAGSSSQLTEPSVIQQPSISAPNM 194
            G R    A   +     PG  G +   G R    PP    S  L  P V  +P    P  
Sbjct: 1468 GPRGPPGAIGPKGDRGFPGPLGEAGEKGERG---PPGPAGSRGL--PGVAGRPGAKGPEG 1522

Query: 195  P 195
            P
Sbjct: 1523 P 1523



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 53/192 (27%), Positives = 66/192 (34%), Gaps = 28/192 (14%)

Query: 17   GPPGPETPPPAPAPTARPRLR----LPAPDWRARRADLTRR-------KGLRRGEPGSRG 65
            G PGP  PP    P   P  R    LP    +  + D   R        G+  GEPG  G
Sbjct: 1368 GDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPG 1427

Query: 66   L--GEGPAAARRPQVQSIDTTPSGEGAPSF-SRAQRPGRSGP-SPSLASDPAPGRGAAWG 121
            L    GP     P  +  +   S +GAP    +   PG  GP  P  A  P   RG    
Sbjct: 1428 LPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGF--- 1484

Query: 122  SLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPP-CAGSSSQLTE 180
               PG        EAG +  R          +PG     PG +    PP   G   +  E
Sbjct: 1485 ---PGPL-----GEAGEKGERGPPGPAGSRGLPGVAG-RPGAKGPEGPPGPTGRQGEKGE 1535

Query: 181  PSVIQQPSISAP 192
            P     P++  P
Sbjct: 1536 PGRPGDPAVVGP 1547



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 46/156 (29%), Positives = 52/156 (33%), Gaps = 22/156 (14%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGL----GE---- 68
            GPPG   PP       RP    P P     R      KG   G PG  GL    GE    
Sbjct: 1604 GPPGDSGPPGEKGDPGRPGP--PGPVGPRGRDGEVGEKG-DEGPPGDPGLPGKAGERGLR 1660

Query: 69   GPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKR 128
            G    R P  +  D    GE   + S    PG SGP         PG         PG R
Sbjct: 1661 GAPGVRGPVGEKGDQGDPGEDGRNGS----PGSSGPKGDRGEPGPPGPPGRLVDTGPGAR 1716

Query: 129  QQALESEAGGRASREARAAEVRERIPGGGSWCPGRR 164
            +   + E G R     R  +    +PG     PG R
Sbjct: 1717 E---KGEPGDRGQEGPRGPKGDPGLPG----APGER 1745



 Score = 36.2 bits (82), Expect = 0.018
 Identities = 51/166 (30%), Positives = 60/166 (36%), Gaps = 25/166 (15%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
            GPPGP+  P    P      R P          L  R GL  G+PG+ G      AA + 
Sbjct: 1752 GPPGPQGDPGVRGPAGEKGDRGP--------PGLDGRSGL-DGKPGAAGPSGPNGAAGKA 1802

Query: 77   QVQSIDTTPSGEGAPSFSRAQ-RPGRSGPSPSLASDPA----PGRGAAWGSL-RPGKRQQ 130
                    P  +G P     Q  PG SGP P L   P     PG     G    PG+  +
Sbjct: 1803 ------GDPGRDGLPGLRGEQGLPGPSGP-PGLPGKPGEDGKPGLNGKNGEPGDPGEDGR 1855

Query: 131  ALESEAGGRASREARAAEVRER-IPG--GGSWCPGRRDWLTPPCAG 173
              E    G + RE R     ER  PG  G    PG    + PP  G
Sbjct: 1856 KGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQG 1901



 Score = 33.1 bits (74), Expect = 0.16
 Identities = 45/161 (27%), Positives = 55/161 (34%), Gaps = 15/161 (9%)

Query: 16   DGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLG-----EGP 70
            +G PGP  PP  P     P       D       L   +G  RGEPG RG       EGP
Sbjct: 2433 EGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRG-ERGEPGIRGEDGRPGQEGP 2491

Query: 71   AAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQ 130
                 P     +    G+       A   G  G S  +   P P RGA       G R  
Sbjct: 2492 RGLTGPPGSRGERGEKGD----VGSAGLKGDKGDSAVILGPPGP-RGAKGDMGERGPR-- 2544

Query: 131  ALESEAGGRASREARAAEVRERIPG--GGSWCPGRRDWLTP 169
             L+ + G R        +  +  PG  G +  PG R  L P
Sbjct: 2545 GLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGP 2585



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 46/162 (28%), Positives = 59/162 (36%), Gaps = 30/162 (18%)

Query: 20   GPETPPPAPAPTARPRLRLP-APDWRARRADL--TRRKGLRRGEPGSRGLGEGP------ 70
            GP+ PP  P P   P    P  P     + D   T  KG  +G PG RGL   P      
Sbjct: 1884 GPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKG-EQGLPGERGLRGEPGSVPNV 1942

Query: 71   ----------AAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAW 120
                      A+A R  V++ D + SG   P   R     R GP         PG+    
Sbjct: 1943 DRLLETAGIKASALREIVETWDES-SGSFLPVPER-----RRGPKGDSGEQGPPGKEGPI 1996

Query: 121  GSLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPG 162
            G   PG+R   L+ + G    +      + ER P G S   G
Sbjct: 1997 GF--PGER--GLKGDRGDPGPQGPPGLALGERGPPGPSGLAG 2034



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 31/118 (26%), Positives = 43/118 (36%), Gaps = 15/118 (12%)

Query: 57   RRGEPGSRGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQ----------RPGRSGPSP 106
            ++GEPG  GL         P +      P  +G P  + A+          RPG  G + 
Sbjct: 1255 QKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAG 1314

Query: 107  SLASDPAPGRGAAWGSLRPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRR 164
            +  +  APG   + G   PG R    E    G         +V   I G G   PGR+
Sbjct: 1315 NPGTPGAPGLKGSPG--LPGPRGDPGERGPRGPKGEPGAPGQV---IGGEGPGLPGRK 1367



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 19/103 (18%)

Query: 16   DGPPGPE-TPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLR--RGEPGSRGLGEGPAA 72
            DGPPG   TP P   P  +  +  P P     +       GL+  +GEPGS G  +GP  
Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGP----PGLKGAKGEPGSNG-DQGPKG 2129

Query: 73   AR----------RPQVQSIDTTPSGEGAPSFSRAQ-RPGRSGP 104
             R           P  +  D  P   G    +  + +PG  GP
Sbjct: 2130 DRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGP 2172



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 41/153 (26%), Positives = 53/153 (34%), Gaps = 22/153 (14%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPG-----SRGLGEGPA 71
            GPPGP      P P   P L  PA              GL +GEPG      RGL     
Sbjct: 2174 GPPGPVGGHGDPGPPGAPGLAGPAGP--------QGPSGL-KGEPGETGPPGRGLTGPTG 2224

Query: 72   AARRPQVQSIDTTPSGEGAPSF-------SRAQRPGRSGPSPSLASDPAPGRGAAWGSLR 124
            A   P           +G+P          +   PGR G S       +PG   + G   
Sbjct: 2225 AVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPG 2284

Query: 125  P-GKRQQALESEAGGRASREARAAEVRERIPGG 156
            P G + +   + A G+A      A+  +  PGG
Sbjct: 2285 PVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGG 2317


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 32/179 (17%)

Query: 4   PARIPCNKILTNDGPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGS 63
           P  +P    L    PP    PPP P P+       PA   ++  + L  +K   RG    
Sbjct: 772 PPALPPPPPLAKFPPPSQPQPPPPPPPS-------PASLLKSLASVLEGQKYCYRGT--- 821

Query: 64  RGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSL 123
                G A + RP    + TT    G PS + A  P  + PS             A GS 
Sbjct: 822 -----GAAVSTRPG--PLPTTQYSPGPPSGATALPPTSAAPS-------------AQGSP 861

Query: 124 RPGKRQQALESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPPCAGSSSQLTEPS 182
           +P     +  S +GG  +RE RA E  E +PG  +          PP    S  L E S
Sbjct: 862 QPSASSSSQFSTSGGPWARERRAGE--EPVPGPMTPTQPPPPLSLPPARSESEVLEEIS 918



 Score = 31.2 bits (69), Expect = 0.59
 Identities = 40/127 (31%), Positives = 44/127 (34%), Gaps = 33/127 (25%)

Query: 18  PPGPETPPPAPAP----TARPRLRLPAPDWRARRAD---------------------LTR 52
           PPGP +PPP P P       P   L  P  RA R D                     L  
Sbjct: 462 PPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPH 521

Query: 53  RKGLRRGEPGSRGLGEGPAAARRPQVQSIDTTP---SGEGAPSFSRAQRPGRSGPSPSLA 109
           R+G   G P SR    G   +  P      TT    S  G+ S S A  P    P P LA
Sbjct: 522 REGF-LGPPASR-FSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPA-GPVSFPPPPYLA 578

Query: 110 S--DPAP 114
              DP P
Sbjct: 579 RSIDPLP 585



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 13/56 (23%)

Query: 18   PPGPETPPPAPAPTARP------------RLRLPAPDWRARRADLTRRKGLRRGEP 61
            PP    PP APAP+A+P            R   P P     RAD+ + + L  G P
Sbjct: 1046 PPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPP-GVSRADMLKLRSLSEGPP 1100



 Score = 27.3 bits (59), Expect = 8.5
 Identities = 44/177 (24%), Positives = 55/177 (31%), Gaps = 18/177 (10%)

Query: 18  PPGPETPPPAPAPTARPRLRLPAPD-WRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
           PP P  PPP P     P  +L  P  W     D     G  R         +G A   R 
Sbjct: 256 PPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAW---GPER---------KGSAPPERQ 303

Query: 77  QVQSIDTTPSGEGAPSFSRAQRPG-RSGPSPSLASDPAPGRGAAWGSL---RPGKRQQAL 132
           + +     P    AP+++ A  PG R  P+      P P    + G L   RP       
Sbjct: 304 EQRHSLPHPYPYPAPAYT-AHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRE 362

Query: 133 ESEAGGRASREARAAEVRERIPGGGSWCPGRRDWLTPPCAGSSSQLTEPSVIQQPSI 189
                 R       A     +P   S  PG     T   + SSS      V   P I
Sbjct: 363 SRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGI 419


>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
          Length = 1159

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 40/124 (32%), Positives = 47/124 (37%), Gaps = 14/124 (11%)

Query: 19  PGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRPQV 78
           P P  PPP  +P +RP L L         A        R  EPG   LG      R P+ 
Sbjct: 20  PSPGAPPPPRSPRSRPLLLLLLLLGACGAAG-------RSPEPGR--LGPHAQLTRVPRS 70

Query: 79  QSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEAGG 138
                   G G    +R   PG  GPSP     PAPG G   G+   G R+    +   G
Sbjct: 71  PPAGRAEPGGGEDRQARGTEPGAPGPSPG----PAPGPGED-GAPAAGYRRWERAAPLAG 125

Query: 139 RASR 142
            ASR
Sbjct: 126 VASR 129


>gi|113416171 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 265

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 46/177 (25%), Positives = 65/177 (36%), Gaps = 38/177 (21%)

Query: 22  ETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRPQVQSI 81
           ET   +   +A PR  L +P  R    +L RR  L +G P      +G        V + 
Sbjct: 5   ETNKGSIGQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKG-------SVSTA 57

Query: 82  DTTPSGEGAPSFS----------RAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQA 131
             T SG  AP  +          RA  P         A+ PAP R        P +++  
Sbjct: 58  TVTSSGASAPGSADPTLGSTAARRASAPWACPAGCCRANAPAPAR-------NPRRKEPR 110

Query: 132 LESEAGGRASREARAAEV--------------RERIPGGGSWCPGRRDWLTPPCAGS 174
            +S A G+++R  RA                 R R   G ++C G R    PP +GS
Sbjct: 111 RQSRATGKSARTRRACASPCRPGRHCGPETARRPRPLAGTTFCGGARVLSNPPPSGS 167


>gi|169166294 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 265

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 44/172 (25%), Positives = 65/172 (37%), Gaps = 28/172 (16%)

Query: 22  ETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRPQVQSI 81
           ET   + + +A PR  L +P  R    +L RR  L +G P      +G  +     V S 
Sbjct: 5   ETNKGSISQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVST--ATVTSF 62

Query: 82  DTTPSGEGAPSFS-----RAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEA 136
             +  G   P+       RA  P         A+ PAP R        P +++   +S A
Sbjct: 63  GASAPGSADPTLGSTAARRASAPWACPAGCCRANAPAPAR-------NPRRKEPRRQSRA 115

Query: 137 GGRASREARAAEV--------------RERIPGGGSWCPGRRDWLTPPCAGS 174
            G+++R  RA                 R R   G ++C G R    PP +GS
Sbjct: 116 TGKSARTRRACASPCRPGRHCGPETARRPRPLAGTTFCGGARVLSNPPPSGS 167


>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo
           sapiens]
          Length = 1747

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 51/170 (30%), Positives = 69/170 (40%), Gaps = 30/170 (17%)

Query: 18  PPGPET-PPPAPAP-----TARPRLRLPAPDWRAR-------RADLTRRKGLRRG---EP 61
           PP P+T PPP PAP        P    P P  RA        +  L  R G       EP
Sbjct: 830 PPPPQTAPPPPPAPYYFDSGPPPAFSPPPPPGRAYDTVRSSFKPGLEARLGAGAAGLYEP 889

Query: 62  GSRGLGEGPAAARRPQVQSI----DTTPSGEGA----PSFSRAQRPGRSGPSPSLASDPA 113
           G+  LG  P   R+ + +S+    D+ P    A    P+ +  +RP R  P P     P 
Sbjct: 890 GA-ALGPLPYPERQKRARSMIILQDSAPESGDAPRPPPAATPPERPKRR-PRPPGPDSPY 947

Query: 114 PGRGAAWGSL----RPGKRQQALESEAGGRASREARAAEVRERIPGGGSW 159
              GA   SL    +P +R+  L  +     ++E  A  V    PGGGS+
Sbjct: 948 ANLGAFSASLFAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPGGGSF 997



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 58/200 (29%), Positives = 74/200 (37%), Gaps = 24/200 (12%)

Query: 12   ILTNDGPPGPETP--PPAPAPTARP--RLRLPAPD-----WRARRADL-TRRKGLRRGEP 61
            IL +  P   + P  PPA  P  RP  R R P PD       A  A L    K  RR  P
Sbjct: 910  ILQDSAPESGDAPRPPPAATPPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSP 969

Query: 62   GSRGLGEGPAAARRPQVQSIDTTPSGEGAPSFSRAQRPGRSGPSP-SLASDPAPGRGAAW 120
              + L    A  R     ++     G G  SF+R   P   GP P  L      G G A+
Sbjct: 970  LVKQLQVEDAQERA----ALAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGAGDGPGLAF 1025

Query: 121  GSLRPGKRQQALESEAGGRASREARAAEVRERIPGGG--SWCPGR----RDWLTPPCAGS 174
            G   P K ++  E     R++       +    PG    S  P R    R   T P AG 
Sbjct: 1026 GGPGPAKDRRLEERR---RSTVFLSVGAIEGSAPGADLPSLQPSRSIDERLLGTGPTAGR 1082

Query: 175  SSQLTEPSVIQQPSISAPNM 194
               L  P    +P +S P++
Sbjct: 1083 DLLLPSPVSALKPLVSGPSL 1102



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 46/167 (27%), Positives = 61/167 (36%), Gaps = 33/167 (19%)

Query: 17   GPPGPETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRP 76
            G PGPE   P        RL+    D R+             GE    GLG     A++ 
Sbjct: 1498 GLPGPEDDKPTVISELSSRLQQLNKDTRSL------------GEEPVGGLGSLLDPAKKS 1545

Query: 77   QVQSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEA 136
             + +     S     S S  + PG             PG GA++ S+RP  R        
Sbjct: 1546 PIAAARLFSSLGELSSISAQRSPG------------GPGGGASY-SVRPSGRYPVAR--- 1589

Query: 137  GGRASREARAAEVRERIPG--GGSWCPGRRDWLTPPCAGSSSQLTEP 181
              RA    + A + ER+ G   G+   GR   LTPP    SS L+ P
Sbjct: 1590 --RAPSPVKPASL-ERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIP 1633



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 10/123 (8%)

Query: 21   PETPPPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGSRGLGEGPAAARRPQVQS 80
            P TP  APAP     +  P P  RA+            G P   G G+G +      V +
Sbjct: 1248 PGTPELAPAPMQSAAVAEPLPSPRAQPPG---------GTPADAGPGQGSSEEEPELVFA 1298

Query: 81   IDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRPGKRQQALESEAGGRA 140
            ++  P+   +      +   R G  P    + A G   A     PG     + S A G+ 
Sbjct: 1299 VNLPPAQLSSSDEETREELARIGLVPP-PEEFANGVLLATPLAGPGPSPTTVPSPASGKP 1357

Query: 141  SRE 143
            S E
Sbjct: 1358 SSE 1360



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 35/104 (33%), Positives = 40/104 (38%), Gaps = 12/104 (11%)

Query: 25   PPAPAPTARPRLRLPAPDWRARRADLTRRKGLRRGEPGS-RGLGEGPAAARRPQVQSIDT 83
            P    P AR   R P+P    + A L R +GL  G  G+ R  G  P    +    SI  
Sbjct: 1581 PSGRYPVAR---RAPSP---VKPASLERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPH 1634

Query: 84   TPSGEG--APSFSRAQRPGRSGPSPSLASDPAPGRGAAWGSLRP 125
             P        S S   R     P PS AS P PG   A G  RP
Sbjct: 1635 EPKEVRFVVRSVSARSRSPSPSPLPSPASGPGPG---APGPRRP 1675


>gi|238859651 pleckstrin homology domain containing family A member
           4 isoform 1 [Homo sapiens]
          Length = 779

 Score = 40.8 bits (94), Expect = 7e-04
 Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 8/115 (6%)

Query: 4   PARIPCNKILTNDGPPGP--ETPPPAPAPTARPRLRLPAP-DWRARRADLTRRKGLRRGE 60
           P  +P  +      PP P  +T PPA   T   R+ +  P DW  +R  L+R    RRG 
Sbjct: 242 PLSLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGP 301

Query: 61  PGSRGLGEGPAAARRPQVQSID-TTPSGEGAPSFSRAQRPGRSGPSPSLASDPAP 114
           P   G G+ P   R PQ  S +  T +  G+P++ +   P   G   S+   P P
Sbjct: 302 PSEAGGGKPP---RSPQHWSQEPRTQAHSGSPTYLQLP-PRPPGTRASMVLLPGP 352


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,579,740
Number of Sequences: 37866
Number of extensions: 793444
Number of successful extensions: 10794
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 215
Number of HSP's successfully gapped in prelim test: 1219
Number of HSP's that attempted gapping in prelim test: 6963
Number of HSP's gapped (non-prelim): 4089
length of query: 196
length of database: 18,247,518
effective HSP length: 97
effective length of query: 99
effective length of database: 14,574,516
effective search space: 1442877084
effective search space used: 1442877084
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.