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Search of human proteins with 201023339
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
(588 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 1214 0.0
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 1177 0.0
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 1038 0.0
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 93 6e-19
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 93 8e-19
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 92 1e-18
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 84 3e-16
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 84 4e-16
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 84 4e-16
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 83 8e-16
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 82 1e-15
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 77 6e-14
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 76 1e-13
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 75 1e-13
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 75 1e-13
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 74 3e-13
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 74 3e-13
gi|146134388 YLP motif containing 1 [Homo sapiens] 74 4e-13
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 72 1e-12
gi|210032580 SET domain containing 1B [Homo sapiens] 72 2e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 71 2e-12
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 70 4e-12
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 69 1e-11
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 68 3e-11
gi|7662018 PHD finger protein 3 [Homo sapiens] 67 4e-11
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 67 6e-11
gi|52426743 cisplatin resistance-associated overexpressed protei... 67 6e-11
gi|19923485 cisplatin resistance-associated overexpressed protei... 67 6e-11
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 66 8e-11
gi|55750053 atrophin-1 [Homo sapiens] 65 1e-10
>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
Length = 588
Score = 1214 bits (3141), Expect = 0.0
Identities = 588/588 (100%), Positives = 588/588 (100%)
Query: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 60
MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
Sbjct: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 60
Query: 61 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 120
PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
Sbjct: 61 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 120
Query: 121 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 180
VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
Sbjct: 121 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 180
Query: 181 RMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKA 240
RMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKA
Sbjct: 181 RMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKA 240
Query: 241 EFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAID 300
EFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAID
Sbjct: 241 EFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAID 300
Query: 301 VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL 360
VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL
Sbjct: 301 VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL 360
Query: 361 PPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPY 420
PPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPY
Sbjct: 361 PPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPY 420
Query: 421 GNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERE 480
GNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERE
Sbjct: 421 GNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERE 480
Query: 481 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRS 540
RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRS
Sbjct: 481 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRS 540
Query: 541 NSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588
NSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
Sbjct: 541 NSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588
>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
Length = 594
Score = 1177 bits (3044), Expect = 0.0
Identities = 579/603 (96%), Positives = 579/603 (96%), Gaps = 24/603 (3%)
Query: 1 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP 45
MSAGEVERLVSELSGGTGGDEEEEWLYG DENEVERPEEENASANP
Sbjct: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 60
Query: 46 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 105
PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
Sbjct: 61 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 120
Query: 106 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 165
NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
Sbjct: 121 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 180
Query: 166 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR 225
NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR
Sbjct: 181 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR 240
Query: 226 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG 285
TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG
Sbjct: 241 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG 300
Query: 286 RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF 345
RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF
Sbjct: 301 RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF 360
Query: 346 PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESG 405
PPGAPPTHLPPPPFLPPPPTVSTAPPLI PPPGFPPPPGAPPPSLIPTIESG
Sbjct: 361 PPGAPPTHLPPPPFLPPPPTVSTAPPLI---------PPPGFPPPPGAPPPSLIPTIESG 411
Query: 406 HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER 465
HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER
Sbjct: 412 HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER 471
Query: 466 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER 525
DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER
Sbjct: 472 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER 531
Query: 526 RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT 585
RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT
Sbjct: 532 RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT 591
Query: 586 PAE 588
PAE
Sbjct: 592 PAE 594
>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
Length = 520
Score = 1038 bits (2684), Expect = 0.0
Identities = 520/588 (88%), Positives = 520/588 (88%), Gaps = 68/588 (11%)
Query: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 60
MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK
Sbjct: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPK 60
Query: 61 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 120
PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK
Sbjct: 61 PKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTK 120
Query: 121 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 180
VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI
Sbjct: 121 VKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRI 180
Query: 181 RMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKA 240
RMGLEVIPVTSTTNKIT VQQGRTGNSEKETALPSTKA
Sbjct: 181 RMGLEVIPVTSTTNKIT-----------------------VQQGRTGNSEKETALPSTKA 217
Query: 241 EFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAID 300
EFTSPPSLFKTGLPPSR RLPGAID
Sbjct: 218 EFTSPPSLFKTGLPPSR------------------------------------RLPGAID 241
Query: 301 VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL 360
VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL
Sbjct: 242 VIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL 301
Query: 361 PPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPY 420
PPPPTVSTAPPLIPPPG FPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPY
Sbjct: 302 PPPPTVSTAPPLIPPPG---------FPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPY 352
Query: 421 GNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERE 480
GNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERE
Sbjct: 353 GNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERE 412
Query: 481 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRS 540
RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRS
Sbjct: 413 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRS 472
Query: 541 NSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588
NSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
Sbjct: 473 NSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 520
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 93.2 bits (230), Expect = 6e-19
Identities = 52/119 (43%), Positives = 69/119 (57%), Gaps = 9/119 (7%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY-AERGY 509
RE++RDR+RDR +ERDRDRDRER+R R+RER D N D R R + ER
Sbjct: 343 RERERDRDRDRTKERDRDRDRERDRDRDRERSSDR-------NKDRSRSREKSRDRERER 395
Query: 510 ERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
ER R + ER RER R RE+E R + + +R E +E D++ R K ++ R KE
Sbjct: 396 EREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKE 454
Score = 77.0 bits (188), Expect = 4e-14
Identities = 52/124 (41%), Positives = 72/124 (58%), Gaps = 25/124 (20%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
RE++R+RER+R+RER+R+R+RERER RERERER+ D++R R E E YE
Sbjct: 393 RERERERERERERERERERERERERERERERERE---------KDKKRDR-EEDEEDAYE 442
Query: 511 R---HRASREKEERHRER----RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563
R R REKE ++ER RE+++TR E+E + RR K++K
Sbjct: 443 RRKLERKLREKEAAYQERLKNWEIRERKKTREYEK--------EAEREEERRREMAKEAK 494
Query: 564 RSKE 567
R KE
Sbjct: 495 RLKE 498
Score = 70.5 bits (171), Expect = 4e-12
Identities = 51/146 (34%), Positives = 76/146 (52%), Gaps = 20/146 (13%)
Query: 450 RREKDRDRERDRDRERDRDRD-RERERTRERERERDHSPTPSVFNSDEERYRYREYAERG 508
R+E +++R R+R+RER+R+R+ RERER RERERER+ ++ER R R ER
Sbjct: 302 RQEIEKER-RERERERERERERRERERERERERERE---------KEKERERER---ERD 348
Query: 509 YERHRASREKEERHRER---RHREKEETRHKS---SRSNSRRRHESEEGDSHRRHKHKKS 562
+R R +R RER R RE+ R+K SR SR R E + R + ++
Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE 408
Query: 563 KRSKEGKEAGSEPAPEQESTEATPAE 588
+ + +E E E+E + E
Sbjct: 409 REREREREREREREREREKDKKRDRE 434
Score = 61.6 bits (148), Expect = 2e-09
Identities = 43/142 (30%), Positives = 73/142 (51%), Gaps = 6/142 (4%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
+ SK D + + E+++ ++ +E +++R RER RERERER+ + ER
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKER---RERERERERERERRERERERERERERE 336
Query: 500 RYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 558
+ +E ER ER R +ER R+R R R+++ R +SS N R E+ R +
Sbjct: 337 KEKE-RERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER 395
Query: 559 HKKSKRSKEGKEAGSEPAPEQE 580
++ +R +E +E E E+E
Sbjct: 396 ERERERERE-RERERERERERE 416
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/158 (23%), Positives = 66/158 (41%), Gaps = 22/158 (13%)
Query: 443 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 502
K W+ ++R + R+ ++E +R+ +R RE +E +R ++ D + YR
Sbjct: 462 KNWEI-----RERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGS 516
Query: 503 EYAERGYERHRASREKEERHRERRHREKEETRHK--------------SSRSNSRRRHES 548
+R +R + E +ER R+R E EE R + + RR +
Sbjct: 517 ALQKRLRDREK-EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575
Query: 549 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATP 586
+ + ++ K+ KE K EP E+E E P
Sbjct: 576 QIKQEPESEEEEEEKQEKEEKR--EEPMEEEEEPEQKP 611
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 6/122 (4%)
Query: 466 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER 525
+ + D+ +RE + RD +E+ R ER RE+E R RER
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327
Query: 526 -----RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 580
R REKE+ R + R R R ++E D R + + + + + + + +E
Sbjct: 328 EREREREREKEKERER-ERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSRE 386
Query: 581 ST 582
+
Sbjct: 387 KS 388
Score = 33.9 bits (76), Expect = 0.43
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 6/60 (10%)
Query: 345 FPP--GAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTI 402
FPP PP +P P PPP PP + PPG P+ P P P L+PT+
Sbjct: 3 FPPHLNRPPMGIPALPPGIPPPQFPGFPPPV-PPGTPMIPVPMSIMAP---APTVLVPTV 58
Score = 30.0 bits (66), Expect = 6.2
Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 341 PPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGI 378
PPP FP G PP P P +P P ++ P + P +
Sbjct: 22 PPPQFP-GFPPPVPPGTPMIPVPMSIMAPAPTVLVPTV 58
>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
Length = 1337
Score = 92.8 bits (229), Expect = 8e-19
Identities = 85/264 (32%), Positives = 106/264 (40%), Gaps = 36/264 (13%)
Query: 342 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGIPITVPPPGFPP------PPG-- 392
PP FPP PP P P +P PP T P ++PPP +P PPP P PPG
Sbjct: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173
Query: 393 ---APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPG-SAPSWPSLVDTSKQWDYY 448
PPPS + ++ SS S + + P+ F HLP P PS
Sbjct: 174 HHNFPPPS-FNSFQNNPSSFLPSANNSSSPH----FRHLPPYPLPKAPS----------- 217
Query: 449 ARREKDRDRERDRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREY 504
RR +R + D R RD R ER R+ RER R D S + SD +R R
Sbjct: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPS 276
Query: 505 AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR--RHKHKKS 562
R YER R + RHR+ R E +K S R S E R K + S
Sbjct: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWS 336
Query: 563 KRSKEGKEAGSEPAPEQESTEATP 586
GK+ E+E E P
Sbjct: 337 DNQSSGKDKNYTSIKEKEPEETMP 360
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 92.0 bits (227), Expect = 1e-18
Identities = 56/147 (38%), Positives = 80/147 (54%), Gaps = 15/147 (10%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
D ++ + RE+ R+RER+R++ERDR+RDR+R+ RERERER+ + ++ER
Sbjct: 698 DREREKERELERERAREREREREKERDRERDRDRDHDRERERERER-------DREKERE 750
Query: 500 RYREYAERGYERHRASREKEERHRER-RHREKEETRHK------SSRSNSRRRHESEEGD 552
R RE ER ER R + ER RER R R+KE R + R + R + E D
Sbjct: 751 REREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRED 810
Query: 553 SHRRHKHKKSKRSKEGKEAGSEPAPEQ 579
+ R H + K K + GS P+P Q
Sbjct: 811 RNPRDGHDERKSKKRYRNEGS-PSPRQ 836
Score = 84.3 bits (207), Expect = 3e-16
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 12/141 (8%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
+ +++ D R+++R+RER+R+R+R+R+++RE ER R RERER+ D ER
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREK-----ERDRERD 728
Query: 500 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 558
R R++ ER ER R ++ ER RE R RE+E R + R E E + R K
Sbjct: 729 RDRDHDRERERERERDREKEREREREERERERERERER------ERERERERERARERDK 782
Query: 559 HKKSKRSKEGKEAGSEPAPEQ 579
++ +R E K+ G + E+
Sbjct: 783 ERERQRDWEDKDKGRDDRREK 803
Score = 77.8 bits (190), Expect = 3e-14
Identities = 51/131 (38%), Positives = 69/131 (52%), Gaps = 17/131 (12%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
R +R RERDR+RERDR+R+RERER R+RERE++ + ER R RE E
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKER---------ELERERARER-----E 716
Query: 511 RHRASREKEERHRERRH-REKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGK 569
R R ER R+R H RE+E R + R R R E R + ++ +R +E +
Sbjct: 717 REREKERDRERDRDRDHDRERERERER-DREKEREREREERERERERERERERERERE-R 774
Query: 570 EAGSEPAPEQE 580
E E E+E
Sbjct: 775 ERARERDKERE 785
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/154 (31%), Positives = 76/154 (49%), Gaps = 18/154 (11%)
Query: 446 DYYARREKDRDRERDRDRERDR-DRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 504
D+ RE++R+R+R+++RER+R +R+RERER RERERER+ D+ER R R++
Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERERE-RERARERDKERERQRDW 790
Query: 505 AERGYERHRASREKEERHRERRHREKEETRHKSSR-----------SNSRRRHESEEGDS 553
++ R ++EE +R R+ + R R S RRR S + D+
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDA 850
Query: 554 HRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPA 587
+ K K S+ QES +P+
Sbjct: 851 YNSGDDKNEKH-----RLLSQVVRPQESRSLSPS 879
Score = 70.5 bits (171), Expect = 4e-12
Identities = 54/132 (40%), Positives = 68/132 (51%), Gaps = 21/132 (15%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 509
R E+ DR DR ER R+RDRERER RERERER+ ER R RE ER
Sbjct: 660 REERRVDRVDDRRDERARERDRERERDRERERERER-----------ERDRERE-KEREL 707
Query: 510 ERHRASREKEERHRERRHREKEETRHKS-SRSNSRRRHESEEGDSHRRHKHKKSKRSKEG 568
ER RA RE+E R REKE R + R + R R E D + + ++ +R +E
Sbjct: 708 ERERA-RERE------REREKERDRERDRDRDHDRERERERERDREKEREREREERERE- 759
Query: 569 KEAGSEPAPEQE 580
+E E E+E
Sbjct: 760 RERERERERERE 771
Score = 60.1 bits (144), Expect = 6e-09
Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 8/132 (6%)
Query: 443 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 502
++WD A +KD R RDRDR R+R+R+RER++ R+ +RER+ + SV D +R R R
Sbjct: 1321 REWDRDA--DKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSV-ERDRDRDRDR 1377
Query: 503 EYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKS 562
+ E S ++ E E H E+ + S + + R + + G + KS
Sbjct: 1378 TFESSQIE----SVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKS 1433
Query: 563 KRSKEGKEAGSE 574
+R+ E EAG +
Sbjct: 1434 ERT-ESLEAGDD 1444
Score = 57.0 bits (136), Expect = 5e-08
Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 15/147 (10%)
Query: 448 YARREKDRDRERDRDRERDRD---RDRERERTRERERERDHSPTPSVFNSDEERYRYREY 504
+ RR +RDR +R+R++ R + R ER+ R+ V + +ER R R+
Sbjct: 622 FERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERD- 680
Query: 505 AERGYERHRASREKEERHRER-----------RHREKEETRHKSSRSNSRRRHESEEGDS 553
ER +R R + ER RER R RE+E + + + R H+ E
Sbjct: 681 RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740
Query: 554 HRRHKHKKSKRSKEGKEAGSEPAPEQE 580
R + K+ +R +E +E E E+E
Sbjct: 741 RERDREKEREREREERERERERERERE 767
Score = 54.7 bits (130), Expect = 2e-07
Identities = 42/149 (28%), Positives = 63/149 (42%), Gaps = 50/149 (33%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERE------------------------------ 480
RE++R+RER+R+RER R+RD+ERER R+ E
Sbjct: 762 RERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERK 821
Query: 481 ------------------RERDHSPTPSVFNS-DEERYRYREYAERGYERHRASREKEER 521
R R+HSP +NS D++ ++R ++ + S
Sbjct: 822 SKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHL 881
Query: 522 HRERRHREKEETRHKSSRSNSRRRHESEE 550
+R+ R KEE R K R S RR+E +E
Sbjct: 882 TEDRQGRWKEEDR-KPERKESSRRYEEQE 909
Score = 50.8 bits (120), Expect = 3e-06
Identities = 76/356 (21%), Positives = 133/356 (37%), Gaps = 50/356 (14%)
Query: 230 EKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAES 289
+KE + +++ + PSL K+ P R S+ S S RK ++ D+ +++
Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKT 253
Query: 290 PDLR----RLPGAIDVIGQTITIS-----------RVEGRRRANENSNIQVLSERSATEV 334
+ R P I + I + R+E + R ++ +R +
Sbjct: 254 NQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRD- 312
Query: 335 DNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAP 394
KP P G + + + S+ P P T P P +
Sbjct: 313 -----KPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRT-PSPSYQR----- 361
Query: 395 PPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKD 454
+L P + RSA +P +++ P S P S + + D+ R +
Sbjct: 362 --TLTPPLR---------RSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDH-ERTSQS 409
Query: 455 RDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRA 514
DR +R + RDRE++ ERE E+D S + + E R G +R R
Sbjct: 410 HDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPR--------DGRDR-RD 460
Query: 515 SREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 570
+R+ +R R R+ ++R R SR ES + R + R +EG++
Sbjct: 461 ARDTRDRRELRDSRDMRDSR--EMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRD 514
Score = 49.7 bits (117), Expect = 8e-06
Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Query: 435 WPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNS 494
WP D + + RE+D+ R+ DR+RER ER+R R+R+R + S SV
Sbjct: 1331 WPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESV--- 1387
Query: 495 DEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSH 554
+R + E + SR+ +ER ++ + + S R E GD
Sbjct: 1388 --KRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDE 1445
Query: 555 RRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
+ S S G+ G EP + E E
Sbjct: 1446 SKLDDAHSLGSGAGE--GYEPISDDELDE 1472
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/184 (24%), Positives = 74/184 (40%), Gaps = 26/184 (14%)
Query: 426 PHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRD-RERDRDRDRERERTRERERE-- 482
P P P P + K++ + KDR E+ RD ++R RD +R+RE+ R++ R
Sbjct: 261 PRTPSPPPPIPEDIALGKKYKE-KYKVKDRIEEKTRDGKDRGRDFERQREK-RDKPRSTS 318
Query: 483 ---RDHSPTPSVFNSDEERY-----------RYREYAERGYER------HRASREKEERH 522
+ HSP S +S + R + Y+R R++
Sbjct: 319 PAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHS 378
Query: 523 RERRHREKEETRHKSS-RSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQES 581
R++ RH+S R R HE RRH+ ++ R K +E S E E
Sbjct: 379 LSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQ 438
Query: 582 TEAT 585
+++
Sbjct: 439 DQSS 442
Score = 39.7 bits (91), Expect = 0.008
Identities = 42/140 (30%), Positives = 60/140 (42%), Gaps = 17/140 (12%)
Query: 446 DYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSD--EERYRYRE 503
D R E R DR R R + E +R+ HS + S + D +ER RY
Sbjct: 1252 DQLKRGEPSRSTSSDRQDSRSHS---SRRSSPESDRQV-HSRSGSFDSRDRLQERDRYEH 1307
Query: 504 YAERGYERHRASREKE---------ERHRER-RHREKEETRHKSSRSNSRRRHESEEGDS 553
ER ER R +R++E R+R+R R RE+E R + R + R E DS
Sbjct: 1308 DRERERER-RDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDS 1366
Query: 554 HRRHKHKKSKRSKEGKEAGS 573
R + + R+ E + S
Sbjct: 1367 VERDRDRDRDRTFESSQIES 1386
Score = 31.6 bits (70), Expect = 2.1
Identities = 27/141 (19%), Positives = 56/141 (39%), Gaps = 15/141 (10%)
Query: 458 ERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASRE 517
E + R ++ DR ER+ + R E++ S + E+ E + + +
Sbjct: 883 EDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942
Query: 518 KEERHRERRHREKEETRHKSSRSNSRRRHE-------------SEEGD--SHRRHKHKKS 562
E+R R ++ + + K + +++ E SE+G S ++ + KKS
Sbjct: 943 SEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKS 1002
Query: 563 KRSKEGKEAGSEPAPEQESTE 583
K K G ++E+ +
Sbjct: 1003 IEKKRKKSKGDSDISDEEAAQ 1023
Score = 30.4 bits (67), Expect = 4.7
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 19/145 (13%)
Query: 455 RDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRA 514
++ R R RE++ D +ERT E E E T + +SD Y E E R
Sbjct: 114 KESSRGRHREKE-DIKITKERTPESEEENVEWET-NRDDSDNGDINYDYVHELSLEMKRQ 171
Query: 515 SREKEERHRERRHREKEE------------TRHKSSRSNSRRRHESEEGDSHRRHKHKKS 562
++E E+ + EK E R K S S S R+ R+ K S
Sbjct: 172 KIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSK---SPKRKSSPKSS 228
Query: 563 KRSKEGKE--AGSEPAPEQESTEAT 585
SK+ ++ A S P +Q+ T
Sbjct: 229 SASKKDRKTSAVSSPLLDQQRNSKT 253
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 84.3 bits (207), Expect = 3e-16
Identities = 44/151 (29%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Query: 441 TSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 500
T ++ D R +++DR R RDR R+R RDRE+ER R+ +RERD E
Sbjct: 71 TERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130
Query: 501 YREYAERGYERHRASREKEERHRE---RRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 557
ERG +R + + ER R+ R R+ + R + + N ++ E E+ RR
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190
Query: 558 KHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588
+ ++ ++ + ++ SE E+E T E
Sbjct: 191 RERQREKENKTEDRHSERGRERERERETETE 221
Score = 80.9 bits (198), Expect = 3e-15
Identities = 50/141 (35%), Positives = 75/141 (53%), Gaps = 17/141 (12%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHS-PTPSVFNSDEERYRYREY---AE 506
RE +R RER R+RER+R+R+R+RER RERERER+ T + ER R R+ E
Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Query: 507 RGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEE------------GDS 553
R + R R + ER RER R R+++ R + R R R +E ++
Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414
Query: 554 HRRHKHKKSKRSKEGKEAGSE 574
++ + +K + S+ G+E G E
Sbjct: 415 EKQREREKDRESERGRERGRE 435
Score = 80.9 bits (198), Expect = 3e-15
Identities = 52/155 (33%), Positives = 83/155 (53%), Gaps = 19/155 (12%)
Query: 443 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRY- 501
+Q + RE++R RER+R+RER+R+R RE ER RE+ERER + D ER R
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM---DRERNRQT 359
Query: 502 ----REYAERGYERHR-----ASREKEERHRER---RHREKEETRHK---SSRSNSRRRH 546
R AER ER R ++RE+EER R+R R +E+E K R ++R
Sbjct: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419
Query: 547 ESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQES 581
++ +S R + + + ++G+E E ++++
Sbjct: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQA 454
Score = 79.3 bits (194), Expect = 9e-15
Identities = 49/139 (35%), Positives = 79/139 (56%), Gaps = 7/139 (5%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 509
+RE++R+RER+R+R+R+ +RDRE+ER R+R+R+ + + E R + ER
Sbjct: 316 KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
Query: 510 ERHRAS-REKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
ER R S RE+EER R+R R R+KE R + +R E + R K ++S+R +E
Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ----REREKDRESERGRE 431
Query: 568 -GKEAGSEPAPEQESTEAT 585
G+E + E++ T
Sbjct: 432 RGREREKQKGRERDRERQT 450
Score = 79.0 bits (193), Expect = 1e-14
Identities = 57/163 (34%), Positives = 82/163 (50%), Gaps = 27/163 (16%)
Query: 443 KQWDYYARREKDRDRERDRDRERDRDRDRERERT----------------RERERERDHS 486
+Q D RE+ DRERDR RE++R+R +ERER RERER+RD +
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRD-A 155
Query: 487 PTPSVFNSDEERYRYRE-YAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRR 545
+D ER R E ++ ER + +E+ ER R+R K E RH S R R R
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH-SERGRERER 214
Query: 546 HESEEGDSHR-------RHKHKKSKRSKEGKEAGSEPAPEQES 581
E ++ R R + +K++R +E K+A E A E+E+
Sbjct: 215 ERETETETERKRQTDRERDRQRKTERERE-KQAERERASERET 256
Score = 78.6 bits (192), Expect = 2e-14
Identities = 48/137 (35%), Positives = 73/137 (53%), Gaps = 7/137 (5%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 509
RR+K+R+R+ DR R+R +RDRE ER RER+RER+ N ER R R ER
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERER---NRKRERERER---ERER 327
Query: 510 ERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEG 568
ER R + E+ RER R R+ E R ++ ++ R ++E R + ++S R +E
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 569 KEAGSEPAPEQESTEAT 585
+E + ++E T
Sbjct: 388 RERDRDRDRQKERERQT 404
Score = 76.6 bits (187), Expect = 6e-14
Identities = 50/151 (33%), Positives = 77/151 (50%), Gaps = 12/151 (7%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHS---PTPSVFNSDE 496
+ KQ + E++ +R+++R+RERDRDRDR+R R +ERER+ D T ++
Sbjct: 241 EREKQAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRETER 299
Query: 497 ERYRYREYAERGYERHRASREKEERHRER-------RHREKEETRHKSSRSNSRRRHESE 549
+R R RE ER ER+R + ER RER R REKE R + ++ R +
Sbjct: 300 KRERQRE-RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 550 EGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 580
G RR ++ +R +E + E+E
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERE 389
Score = 74.7 bits (182), Expect = 2e-13
Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 5/133 (3%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
D K+ + RE+ R ER+R +ER+R+++R+ R RER+RE+++ ER
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 500 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSS-----RSNSRRRHESEEGDSH 554
R RE + + RE++ + + R REK+ R ++S R R R + D
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 555 RRHKHKKSKRSKE 567
RR K ++ + ++
Sbjct: 274 RRQKERERQTDRK 286
Score = 74.7 bits (182), Expect = 2e-13
Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 3/141 (2%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
+ +Q D R++ +RER++ ER+R +RE ER +ERERERD + ER
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 500 RYREYAERGYERHRASREKEERHRER-RHREKEETRHKS-SRSNSRRRHESEEGDSHRRH 557
R+ +R ER R + K ER RER R RE+ R + R R R E D +
Sbjct: 283 TDRK-RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
Query: 558 KHKKSKRSKEGKEAGSEPAPE 578
+ K+ ++++ +E + E
Sbjct: 342 ERKRKRQTEMDRERNRQTGRE 362
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/136 (33%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
REK +RER +RE +RD++RERER R+R+R+R +D +R R R +R E
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERER--QTDRKRQR-RTERDRETE 298
Query: 511 RHRASREKEERHRER---RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
R R + + ER RER R RE+E R + + + R E E +R +R+++
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 568 GKEAGSEPAPEQESTE 583
G A + E
Sbjct: 359 TGREGRRQAERERERE 374
Score = 70.5 bits (171), Expect = 4e-12
Identities = 48/165 (29%), Positives = 80/165 (48%), Gaps = 24/165 (14%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRE-------------RERERD-- 484
+ +Q D +R+ +R+R+++R+RE++R RERER RE RERER+
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 485 -HSPTPSVFNSDEERYRYRE---YAERGYERHRASREKEERHRER-----RHREKEETRH 535
+ T +D ER R R+ E+ ER RAS + ER +ER R R+++ +
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
Query: 536 KSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 580
+ R R+R E D K ++ + + +E + E+E
Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
Score = 69.7 bits (169), Expect = 7e-12
Identities = 41/143 (28%), Positives = 77/143 (53%), Gaps = 5/143 (3%)
Query: 442 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDE---ER 498
+K D ++ R ++R+RER+ + E +R R +RER R+R+ ER+ + E ER
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Query: 499 YRYREYAERGYERHRASREKE-ERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 557
+ RE ER +R R R+KE ER +R+ + + E ++ R R+R E + +R+
Sbjct: 259 DKERE-RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 558 KHKKSKRSKEGKEAGSEPAPEQE 580
+ ++ + + ++ +E E+E
Sbjct: 318 ERERERERERERQRETERDREKE 340
Score = 67.8 bits (164), Expect = 3e-11
Identities = 38/127 (29%), Positives = 62/127 (48%), Gaps = 9/127 (7%)
Query: 450 RREKDRDRERDRDRERDRDRDRER--ERTRERERERDHSPTPSVFNSDEERYRYREYAER 507
+RE++R R+ +++RER DR+R+R ER R++ERER+ N E R R R+ +
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREK-------NRQERRERERQREKE 198
Query: 508 GYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
R S ER RER + E + ++ R R+R E + + + ++
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Query: 568 GKEAGSE 574
KE E
Sbjct: 259 DKERERE 265
Score = 64.7 bits (156), Expect = 2e-10
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
D K+ + +R+ + DRER+R R+ R ERER RERER+R + D +R
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 500 RYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 558
R +E ER E+ R + + E+ RER + RE E R + ++ E + R
Sbjct: 396 RQKE-RERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQA 454
Query: 559 HKKSKRS 565
++ KRS
Sbjct: 455 GRQRKRS 461
Score = 64.3 bits (155), Expect = 3e-10
Identities = 44/133 (33%), Positives = 63/133 (47%), Gaps = 16/133 (12%)
Query: 451 REKDRDRERDR----DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAE 506
REK+R+R+R R DRER+R RE R ERERER+ + +R RE E
Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERER---------ERDRQSAREREE 387
Query: 507 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
R +R R +++ ER E+ + ET + R R ESE G R + K+ R +
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR---ESERGRERGREREKQKGRER 444
Query: 567 EGKEAGSEPAPEQ 579
+ + A Q
Sbjct: 445 DRERQTDRQAGRQ 457
Score = 63.2 bits (152), Expect = 7e-10
Identities = 46/154 (29%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Query: 440 DTSKQWDYYARREKDRDRERDRDR---------ERDRDRDRERERTRERERERDHSPTPS 490
+ ++Q RR+ +R+RER+R+R ER+RDRDR+R++ RER+ E+D
Sbjct: 354 ERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE 413
Query: 491 VFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSN-------SR 543
ER + RE +ERG ER R +++ R R+R + + + RS
Sbjct: 414 T-EKQREREKDRE-SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRT 471
Query: 544 RRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAP 577
R + D +R + + K S E +A S P
Sbjct: 472 ARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFP 505
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/163 (30%), Positives = 73/163 (44%), Gaps = 19/163 (11%)
Query: 428 LPGSAPSWPSL-VDTSKQWDYYARREKDRDRERDRD-----RERDRDRDRERERTRERER 481
+P +A +L V+ + D+ RR ++ R R ++ D D DRER R +ERER
Sbjct: 6 VPATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGD-DRERNRQKERER 64
Query: 482 ERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRS 540
R+ T +D +R R RE +RHR K +RHRER R REKE R
Sbjct: 65 RREKRQTER--ETDRKRERRRE-----KDRHR----KRDRHRERQRDREKERERQTDRER 113
Query: 541 NSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
+ +R E R ++ +R ++ + G Q E
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 84.0 bits (206), Expect = 4e-16
Identities = 52/152 (34%), Positives = 82/152 (53%), Gaps = 10/152 (6%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHS---PTPSVFNSDE 496
D ++ D REK+R+R+++RDR+R R+R+ ERE R+RER+R T + D
Sbjct: 41 DRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDR 100
Query: 497 ERYRYREYAERGYERHR-ASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR 555
+R R RE +R ER+R RE++++ R RE+E R + R R+R E D R
Sbjct: 101 DRERKRE-TDRNRERNRKGGRERDKQTERERDRERERQRQRE-RERQRQRERKRETDRER 158
Query: 556 RH----KHKKSKRSKEGKEAGSEPAPEQESTE 583
+ + +K +R KE K+ E E++ E
Sbjct: 159 QRWAEREERKKERKKERKKERKEKKKEEKRRE 190
Score = 75.5 bits (184), Expect = 1e-13
Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 5/138 (3%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDR--DRDRERERTRERERERDHSPTPSVFNSDEE 497
D +Q + RE +R RER R RER R DR+R+++R RER+RE D + + E
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN-RKGGRE 121
Query: 498 RYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRR 556
R + E ER ER R + + ER R+R R RE + R + + R++ +E R+
Sbjct: 122 RDKQTE-RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
Query: 557 HKHKKSKRSKEGKEAGSE 574
K K+ KR ++ K E
Sbjct: 181 EKKKEEKRREDKKRKWGE 198
Score = 74.3 bits (181), Expect = 3e-13
Identities = 54/172 (31%), Positives = 80/172 (46%), Gaps = 29/172 (16%)
Query: 440 DTSKQWDYYARRE-----KDRDRERDRDRERDRDRDRERERTRERERERDHS---PTPSV 491
+T ++ D RE ++R R+RDR RERDR DRE+ER R++ER+R T
Sbjct: 16 ETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERE 75
Query: 492 FNSDEERYRYREY-----AERGYERHRASREKEERHRER---------------RHREKE 531
ER R RE ER +R R + + +R+RER R RE+E
Sbjct: 76 TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
Query: 532 ETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
R + R R+R E D R+ ++ +R KE K+ + E++ E
Sbjct: 136 RQRQR-ERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEE 186
Score = 73.6 bits (179), Expect = 5e-13
Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 8/134 (5%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
R+++R RE DR +E +R+RDR+RER + ERE H D R R R+ +R E
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHR------QRDRHRERDRQ-TDREKE 55
Query: 511 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR-RHKHKKSKRSKEGK 569
R R +R RER + E + + R R+R E D R R + +++ R++E
Sbjct: 56 RERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
Query: 570 EAGSEPAPEQESTE 583
G +Q E
Sbjct: 116 RKGGRERDKQTERE 129
Score = 65.1 bits (157), Expect = 2e-10
Identities = 45/136 (33%), Positives = 72/136 (52%), Gaps = 13/136 (9%)
Query: 450 RREKDRDRE--RDRDRERDRDRDRERE---RTRERERERDHSPTPSVFNSDEERYRYREY 504
+RE DR +E R+RDR+R+R+ ERE R R+R RERD + ++ER R +E
Sbjct: 8 KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQT-----DREKERERQKE- 61
Query: 505 AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKR 564
+R +R R + + ER RER+ + + + + R R R E D R +++K R
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETD-RNRERNRKGGR 120
Query: 565 SKEGKEAGSEPAPEQE 580
++ K+ E E+E
Sbjct: 121 ERD-KQTERERDRERE 135
Score = 50.8 bits (120), Expect = 3e-06
Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 20/107 (18%)
Query: 464 ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHR 523
ER R+R RE +R +E ERERD R RE E ER R++ +RHR
Sbjct: 2 ERQRERKRETDRGKETERERD---------------RQRE-RENQTERENRHRQR-DRHR 44
Query: 524 ER---RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
ER REKE R K +R E+E +R + ++ +R ++
Sbjct: 45 ERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQ 91
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/76 (22%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Query: 510 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGK 569
ER R + + +R +E RE++ R + +++ RH + R + + K + K
Sbjct: 2 ERQRERKRETDRGKETE-RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 570 EAGSEPAPEQESTEAT 585
E + E+E+ T
Sbjct: 61 ERDRQRQRERETERET 76
>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
Length = 1374
Score = 84.0 bits (206), Expect = 4e-16
Identities = 74/222 (33%), Positives = 93/222 (41%), Gaps = 34/222 (15%)
Query: 342 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGIPITVPPPGFPP------PPG-- 392
PP FPP PP P P +P PP T P ++PPP +P PPP P PPG
Sbjct: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173
Query: 393 ---APPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPG-SAPSWPSLVDTSKQWDYY 448
PPPS + ++ SS S + + P+ F HLP P PS
Sbjct: 174 HHNFPPPS-FNSFQNNPSSFLPSANNSSSPH----FRHLPPYPLPKAPS----------- 217
Query: 449 ARREKDRDRERDRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREY 504
RR +R + D R RD R ER R+ RER R D S + SD +R R
Sbjct: 218 ERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPS 276
Query: 505 AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRH 546
R YER R + RHR+ R E +K S R +
Sbjct: 277 RHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSY 318
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 82.8 bits (203), Expect = 8e-16
Identities = 48/148 (32%), Positives = 81/148 (54%), Gaps = 11/148 (7%)
Query: 450 RREKDRDRERD--RDRERDRDRDRER--ERTRERERERDHSPTPSVFNSDEERYRYREYA 505
RR++DR+RE++ R R RDRD D+ER ER +ERER R+ S EE+ +
Sbjct: 349 RRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKD 408
Query: 506 ERGYERHRASREKEERH-----RERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHK 560
+R + + +KE++H RER+HR + +R+ RS SR + +S + K K
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSK--HKNESKEK 466
Query: 561 KSKRSKEGKEAGSEPAPEQESTEATPAE 588
+KRS+ G + ++ + + E +P++
Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKREHSPSK 494
Score = 76.3 bits (186), Expect = 8e-14
Identities = 50/143 (34%), Positives = 71/143 (49%), Gaps = 15/143 (10%)
Query: 439 VDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEER 498
++ K+ R K+R++ER R R DR +R R R+RER R R S D +R
Sbjct: 295 LEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR 354
Query: 499 YRYREY-----------AERGYERHRASREKEERHRERRHR-EKEETRHKSSRSNSRRRH 546
R +E ERG ER + ER +E+R R E EE +HK + + RRH
Sbjct: 355 EREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDD--RRH 412
Query: 547 ESEEGDSHRRHKHKKSKRSKEGK 569
++ DS + KH +S RS+E K
Sbjct: 413 RDDKRDSKKEKKHSRS-RSRERK 434
Score = 62.0 bits (149), Expect = 1e-09
Identities = 46/144 (31%), Positives = 66/144 (45%), Gaps = 29/144 (20%)
Query: 446 DYYARREKDRDRERDRDRER-----------------DRDRDRERERTRERERERDHSPT 488
DY R +R++ER+R RER D+D R R+ R+ ++E+ HS +
Sbjct: 369 DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRS 428
Query: 489 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 548
S R R R +R R S+EK +H+ E +E +K SRS S+ R +S
Sbjct: 429 RSRERKHRSRSRSRNAGKRSRSR---SKEKSSKHK----NESKEKSNKRSRSGSQGRTDS 481
Query: 549 EEGDSHRRH-----KHKKSKRSKE 567
E R H K +K RSKE
Sbjct: 482 VEKSKKREHSPSKEKSRKRSRSKE 505
Score = 60.5 bits (145), Expect = 4e-09
Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 12/129 (9%)
Query: 450 RREKDRDRERDR------DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYRE 503
RR + R R+ DRE +R+++R+R +ERE++ + S+ E R
Sbjct: 274 RRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERR----- 328
Query: 504 YAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563
R ERHR+ +R +RR R++E + R ++ E G+ + + + +
Sbjct: 329 -RSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRE 387
Query: 564 RSKEGKEAG 572
RSKE + G
Sbjct: 388 RSKEQRSRG 396
Score = 52.8 bits (125), Expect = 9e-07
Identities = 49/159 (30%), Positives = 66/159 (41%), Gaps = 24/159 (15%)
Query: 453 KDRDRERDRD-RERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYRE-------- 503
K R R+ +D +E + DR ER R R R SP S S R +RE
Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRS-RSRSHHREGHGSSSFD 292
Query: 504 -YAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR------- 555
ER ER R RE +ER +ERR + + RS SR RH S R
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR 352
Query: 556 -RHKHKKSKRSKE-----GKEAGSEPAPEQESTEATPAE 588
R + K+++R + KE G+E E+E + E
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRERSKE 391
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 453 KDRDRERDRDRERDRDRDRERERT-RERERERDHSPTPSVFNSDEERYRYREYAERGYER 511
+ RD +RD +E+ R R RER R R R R+ + ++ E E+ +R
Sbjct: 411 RHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR 470
Query: 512 HRAS----REKEERHRERRHREKEETRHKSSRSNSR--RRHESEEGDSHRRHKHKKSK 563
R+ + E+ ++R H +E K SRS R +R S+ D +H ++S+
Sbjct: 471 SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQ 528
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/122 (22%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRER-ERERDHSPTPSVFNSDEERYRYREYAERG 508
+R+ ++++ R R R+R + R R R+R +R R S S + +E + + + + G
Sbjct: 416 KRDSKKEKKHSRSRSRER-KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG 474
Query: 509 YERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEG 568
+ S EK ++ +EK R +S + +R H + S + + + +E
Sbjct: 475 SQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQES 534
Query: 569 KE 570
+E
Sbjct: 535 QE 536
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 30/141 (21%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERE--------------RDHSPTPSVFNSD 495
+ ++D+D R RD +RD ++++ R+R RER+ R S S + +
Sbjct: 402 KHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKN 461
Query: 496 EERYRYREYAERGYE------------RHRASREKEE---RHRERRH-REKEETRHKSSR 539
E + + + + G + H S+EK R +ER H R+ +++ +S +
Sbjct: 462 ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDK 521
Query: 540 SNSRRRHESEEGDSHRRHKHK 560
+ RR E+ ++HK+K
Sbjct: 522 HDRRRSQSIEQESQEKQHKNK 542
Score = 38.9 bits (89), Expect = 0.013
Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 15/78 (19%)
Query: 456 DRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 515
++ + R+ +++ R+R R++ER +RDHS + SD+ ++R R S
Sbjct: 483 EKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKD--QSDK------------HDRRR-S 527
Query: 516 REKEERHRERRHREKEET 533
+ E+ +E++H+ K+ET
Sbjct: 528 QSIEQESQEKQHKNKDET 545
Score = 33.9 bits (76), Expect = 0.43
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 439 VDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHS 486
V+ SK+ ++ +EK R R R ++R RD ++++ + +R R S
Sbjct: 482 VEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQS 529
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 82.0 bits (201), Expect = 1e-15
Identities = 53/156 (33%), Positives = 83/156 (53%), Gaps = 13/156 (8%)
Query: 441 TSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERD-HSPTPSVFNSDEERY 499
T + D ++K R+RERDR RER+RDRDRE+ER R+ E++RD T + D ER
Sbjct: 119 TEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRERE 178
Query: 500 RYRE-YAERGYERHRASREKEERHRER-RHREKE-------ETRHKSSRSNSRRR---HE 547
+ +E ER +R R + ++ ER +R R R+++ ET + R RRR +
Sbjct: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD 238
Query: 548 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
+ G R + +K +R KE K+ + E++ E
Sbjct: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEE 274
Score = 75.9 bits (185), Expect = 1e-13
Identities = 48/139 (34%), Positives = 71/139 (51%), Gaps = 16/139 (11%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
D Q + RE+DR+RE+ ++RE +RDRDR+R+ +ERER+ +D ER
Sbjct: 160 DRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQ-----------TDRERD 208
Query: 500 RYRE-YAERGYERHRASREKEERHRER---RHREKEETRHKSSRSNSRRRHESEEGDSHR 555
R R+ ER E R + +R RER R R KE R + R R++ +E R
Sbjct: 209 RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER-DRKEERKKERKKERKKER 267
Query: 556 RHKHKKSKRSKEGKEAGSE 574
+ K K+ KR ++ K E
Sbjct: 268 KEKKKEEKRREDKKRKWGE 286
Score = 69.3 bits (168), Expect = 9e-12
Identities = 43/134 (32%), Positives = 76/134 (56%), Gaps = 10/134 (7%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYRE-YAERG 508
R+EK+ +R RDR+++ + +RDRERE+ + RERERD + ER R RE ER
Sbjct: 104 RKEKETNRNRDREKQTEIERDREREKQKGRERERDR-------GRERERDRDREKERERQ 156
Query: 509 YERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
E+ R + + E RER R REK++ R ++ R R+R +E + + + ++++
Sbjct: 157 TEKDRDGQRETETERERDREREKQKER-ETERDRDRQRDTEKERERQTDRERDRQRKTQT 215
Query: 568 GKEAGSEPAPEQES 581
++ ++ E+E+
Sbjct: 216 ERQRETDREGERET 229
Score = 67.8 bits (164), Expect = 3e-11
Identities = 40/131 (30%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Query: 443 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 502
K+ + R++++ E +RDRER++ + RERER R RERERD D E+ R R
Sbjct: 105 KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDR---------DREKERER 155
Query: 503 EYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR-RHKHKK 561
+ E+ + R + + ER RER +++ ET R + + D R R + +
Sbjct: 156 Q-TEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQ 214
Query: 562 SKRSKEGKEAG 572
++R +E G
Sbjct: 215 TERQRETDREG 225
Score = 63.9 bits (154), Expect = 4e-10
Identities = 45/150 (30%), Positives = 75/150 (50%), Gaps = 14/150 (9%)
Query: 450 RREKDR-----DRERDRDRERDRDRDR-ERERTRERERERDHSPTPSVFNSDEERYRYRE 503
+RE+DR ++ERDRDR+RDR+R R E+E R R+RE+ T + + E+ + RE
Sbjct: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQ---TEIERDREREKQKGRE 134
Query: 504 -YAERGYERHRASREKEERHR----ERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 558
+RG ER R ++ER R +R + + ET + R +++ E D R+
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
Query: 559 HKKSKRSKEGKEAGSEPAPEQESTEATPAE 588
+K + + +E + + E T E
Sbjct: 195 TEKERERQTDRERDRQRKTQTERQRETDRE 224
Score = 63.2 bits (152), Expect = 7e-10
Identities = 43/121 (35%), Positives = 63/121 (52%), Gaps = 13/121 (10%)
Query: 451 REKDRDRERDR-DRERDRDRDRERERTR---ERERERDHSPTPSVFNSDEERYRYREYAE 506
R+++RDR R++ ++ERDRDR R+RER R E R RD + ER R RE +
Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEI-----ERDRERE-KQ 130
Query: 507 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
+G ER R + ER R+ REKE R + +R E+E R K K+ + +
Sbjct: 131 KGRERERDRGRERERDRD---REKERERQTEKDRDGQRETETERERDREREKQKERETER 187
Query: 567 E 567
+
Sbjct: 188 D 188
Score = 45.4 bits (106), Expect = 1e-04
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 7/124 (5%)
Query: 465 RDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRE 524
+D D D +R+R R+R RE+ T + D +R R R E+ R+R REK+
Sbjct: 70 KDADGD-DRQRERDRVREK----TEKERDRDRKRDRERRRKEKETNRNR-DREKQTEIER 123
Query: 525 RRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA 584
R REK++ R + R R R + + R + +K + + E E E+E +
Sbjct: 124 DREREKQKGRER-ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
Query: 585 TPAE 588
E
Sbjct: 183 RETE 186
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 76.6 bits (187), Expect = 6e-14
Identities = 51/128 (39%), Positives = 71/128 (55%), Gaps = 16/128 (12%)
Query: 448 YARREKDRDRE-RDRDRERDRDRDRERERT-RERERERDHSPTPSVFNSDEERYRYREYA 505
Y RE++R+RE R R+RER+R+RDRERER RERERER+H D+ER R +E
Sbjct: 401 YRERERERERENRQRERERERERDRERERRQREREREREH-------ERDKERQRRKE-- 451
Query: 506 ERGYERHRASREKEERHRERRHREKEETRHKSS---RSNSRRRHESEEGDSHRRHKHKKS 562
+ER RA R++++R R REKE + K RS ++E +
Sbjct: 452 --EWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQV 509
Query: 563 KRSKEGKE 570
KR+ E K+
Sbjct: 510 KRADEWKD 517
Score = 66.2 bits (160), Expect = 8e-11
Identities = 80/284 (28%), Positives = 110/284 (38%), Gaps = 67/284 (23%)
Query: 339 SKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSL 398
+K PF P GAPP L P P +P P I PP PP PP A L
Sbjct: 255 TKADPFPPNGAPP--LGPHPLMPANPWGGPVVDEILPP-------PPPEPPTESAWERGL 305
Query: 399 I----------------PTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTS 442
P E + R F N F P + DT
Sbjct: 306 RHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPR--DVRDTV 363
Query: 443 KQ------WDYYARR-------EKDRDRERDRD-----RERDRDRDRE-RERTRERERER 483
+ +DY R E R + + + RER+R+R+RE R+R RERERER
Sbjct: 364 LEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERER 423
Query: 484 DHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSR 543
D R RE +R ER R + ER +ER+ R++E R ++ R
Sbjct: 424 D---------------RERERRQRERERER----EHERDKERQRRKEEWERERAKRDEKD 464
Query: 544 RRHESEEGDSHR-RHKHKKSKRSKEGKEAGSEPAPEQESTEATP 586
R+H + + R + K K RS + +EP P++E+ P
Sbjct: 465 RQHRDRDREKEREKEKGKPKPRSPQPPSRQAEP-PKKEAATTGP 507
Score = 60.1 bits (144), Expect = 6e-09
Identities = 41/141 (29%), Positives = 73/141 (51%), Gaps = 8/141 (5%)
Query: 450 RREKDRDRERDRDRER---DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAE 506
+RE++R+RERDR+RER +R+R+RE ER +ER+R ++ DE+ ++R+ +
Sbjct: 414 QRERERERERDRERERRQREREREREHERDKERQRRKEEWERERA-KRDEKDRQHRD-RD 471
Query: 507 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
R ER + + + R + R+ E + +++ + + + E D RR KS + K
Sbjct: 472 REKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRR---SKSPKKK 528
Query: 567 EGKEAGSEPAPEQESTEATPA 587
G A + T A+ A
Sbjct: 529 LGVSVSPSRARRRRKTSASSA 549
Score = 50.1 bits (118), Expect = 6e-06
Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 25/153 (16%)
Query: 450 RREKDRDRERDRDRERDRDRDR-ERERTRERERERDH-------------------SPTP 489
+RE++R+RE +RD+ER R ++ ERER + E++R H SP P
Sbjct: 431 QREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQP 490
Query: 490 SVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESE 549
++ + +E A G + RA K+ R + ++K S S +RRR ++
Sbjct: 491 PSRQAEPPK---KEAATTGPQVKRADEWKDPWRRSKSPKKKLGV--SVSPSRARRRRKTS 545
Query: 550 EGDSHRRHKHKKSKRSKEGKEAGSEPAPEQEST 582
+ + + S RS +GS + + S+
Sbjct: 546 ASSASASNSSRSSSRSSSYSGSGSSRSRSRSSS 578
Score = 45.8 bits (107), Expect = 1e-04
Identities = 90/441 (20%), Positives = 157/441 (35%), Gaps = 95/441 (21%)
Query: 220 KVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGK 279
K +Q R + EKE K + SP PPSR + + + +T + + +
Sbjct: 463 KDRQHRDRDREKEREKEKGKPKPRSPQ-------PPSRQAEPPKKEAATTGPQVKRA-DE 514
Query: 280 WQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDN--- 336
W+D + R++SP + +G +++ SR RR+ + +S S RS++ +
Sbjct: 515 WKDPWRRSKSPKKK--------LGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSG 566
Query: 337 ----------------------------------NFSKPPPFFP--------------PG 348
+FS P P P
Sbjct: 567 SGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPA 626
Query: 349 APP-------THLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPT 401
PP P PP PP T +TAP +P P P P PP
Sbjct: 627 PPPGKAGEKSVKKPAPPPAPPQATKTTAP--VPEPTKPGDPREARRKERPARTPPRRRTL 684
Query: 402 IESGHSSG--YDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRER 459
SG SG Y S+R+ +V+ SA S S + D YA
Sbjct: 685 SGSGSGSGSSYSGSSSRSRSL-SVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSAS 743
Query: 460 DR-----DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRA 514
R +++ + ++ + +E +R+RD S P + + +++ +A
Sbjct: 744 SRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPP---KSAKPPAGGKSSQQPSTPQQA 800
Query: 515 SREKEERHRERRHRE-KEETRHKSSRSNSRRRHESEEGDSH-----RRHKHKKSKRSKEG 568
+ ++ H+E K +K++ SR+R+E + D +R + S++
Sbjct: 801 PPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDR 860
Query: 569 KEAG--SEPAPEQESTEATPA 587
K G P PE++ + + A
Sbjct: 861 KSGGRLGSPKPERQRGQNSKA 881
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 75.9 bits (185), Expect = 1e-13
Identities = 51/155 (32%), Positives = 76/155 (49%), Gaps = 21/155 (13%)
Query: 440 DTSKQWDYYARREKDRDRERD----------RDRERDRDRDRERERTRERERERD-HSPT 488
+ +Q D RE+DRDRER+ R+RERDRDR RE ER R++ERE D H+ T
Sbjct: 45 ERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTET 104
Query: 489 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 548
D ER + + ER ER R ++++ R + ET + R R R
Sbjct: 105 ------DRERQKQK---EREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETG 155
Query: 549 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
E + RH+ ++ +R +E +E E + T+
Sbjct: 156 RERKTEDRHRERERERKRE-RERKRETKERERHTD 189
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/152 (32%), Positives = 76/152 (50%), Gaps = 12/152 (7%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
+ +++ D REK DRE +R RER+RDRDR+RE RER++ER+ T +D ER
Sbjct: 53 ERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERE---TDRHTETDRERQ 109
Query: 500 RYREYA-ERGYERHRASREKEERHRER-----RHREKEETRHKSSRSNSRRRHESEEGDS 553
+ +E ER +R R +++ R R+ R RE++ R R R R +
Sbjct: 110 KQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAER---ERETGRERKTEDRHRE 166
Query: 554 HRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT 585
R + ++ +R +E KE E+E T
Sbjct: 167 RERERKRERERKRETKERERHTDMERERQRET 198
Score = 72.0 bits (175), Expect = 1e-12
Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 13/145 (8%)
Query: 450 RREKDRDRER-------DRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 502
RRE DR+R+R DR ERDR RDRER R R+R+RER+ T ER R R
Sbjct: 24 RRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE-KQTDREGERQRERERDR 82
Query: 503 EYAERGYERHRASREKEERH----RERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 558
+ +R ER R + +RH RER+ +++ E R +++ E + R
Sbjct: 83 D-RQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETD 141
Query: 559 HKKSKRSKEGKEAGSEPAPEQESTE 583
++ ++++ +E G E E E
Sbjct: 142 RERERQAERERETGRERKTEDRHRE 166
Score = 67.8 bits (164), Expect = 3e-11
Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 32/156 (20%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERE------------------------R 475
+ KQ D R+++R+R+RDR RE +R+RD+ERE R
Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
Query: 476 TRERERERDHSPTPSVFNSDEERYRYRE-YAERGYERHRASREKEERHRERRHREKEETR 534
RE+++E +D E R RE AER E R R+ E+RHRE R RE++ R
Sbjct: 123 EREKQKEMGRER-----QTDRETDRERERQAERERETGR-ERKTEDRHRE-RERERKRER 175
Query: 535 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 570
+ + R RH E + R K+ ++ + +E
Sbjct: 176 ERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
Score = 63.2 bits (152), Expect = 7e-10
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
D +Q E+ RDRER++ +E R+R +RE RERER+ + E+R+
Sbjct: 105 DRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRH 164
Query: 500 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGD 552
R RE ER ER R++E + RER + E + ++ R R+R E D
Sbjct: 165 RERE-RERKRER---ERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 62.4 bits (150), Expect = 1e-09
Identities = 43/134 (32%), Positives = 68/134 (50%), Gaps = 17/134 (12%)
Query: 456 DRERDRDRERDRDRDRERE-----RTRERERERDHSPTPSVFNSDEERYRYRE-YAERGY 509
DR+R+R RE DR+RDR +E R ER+R+RD N + +R R RE +R
Sbjct: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRER-----NRERDRDREREKQTDREG 72
Query: 510 ERHRASREKEERHRE---RRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
ER R +R RE R +E+E RH + R R + +E + R ++ K+ +
Sbjct: 73 ERQRERERDRDRQRETERERDKERETDRHTET---DRERQKQKEREMERVRDREREKQKE 129
Query: 567 EGKEAGSEPAPEQE 580
G+E ++ ++E
Sbjct: 130 MGRERQTDRETDRE 143
Score = 30.4 bits (67), Expect = 4.7
Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 517 EKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPA 576
E +R RERR RE + R ++ S + RH + R ++ + + K+ E
Sbjct: 15 ETMDRQRERR-RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGE 73
Query: 577 PEQE 580
++E
Sbjct: 74 RQRE 77
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 75.5 bits (184), Expect = 1e-13
Identities = 49/153 (32%), Positives = 75/153 (49%), Gaps = 27/153 (17%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
D ++ D +EKDR+RER+++ E+DRD+++E+E+ +E+ERE+D S DE+R
Sbjct: 418 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-----EIDEKRK 472
Query: 500 RYRE--YAERGYERHRASREKEERHRERRHREKEET-------RHKSSRSNS-------- 542
+ ++ R Y R SR R RR R + + KSSRS S
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 532
Query: 543 -----RRRHESEEGDSHRRHKHKKSKRSKEGKE 570
R H SE + R +KS ++GKE
Sbjct: 533 KKREKERDHISERRERERSTSMRKSSNDRDGKE 565
Score = 68.2 bits (165), Expect = 2e-11
Identities = 39/143 (27%), Positives = 77/143 (53%), Gaps = 14/143 (9%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
R K++DRE++R+RE++R++++ER + ++R++ER+ D ER R +E+ E+ +
Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK-EKDREREREKEH-EKDRD 446
Query: 511 RHRASREKEERHRER-RHREKEETRHKSSRS-------NSRRRHESEEGDSHRRHKHKKS 562
+ + + +E+ RE+ R +E +E R K +S N+ RR S + RR S
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 506
Query: 563 KRSKEGK----EAGSEPAPEQES 581
+ + K ++ P+P +
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRN 529
Score = 67.4 bits (163), Expect = 4e-11
Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 18/145 (12%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
+ KDRD+ER++DRE+D+++DRERER E+E E+D D+E+ R ++ ++ E
Sbjct: 413 KNKDRDKEREKDREKDKEKDRERER--EKEHEKDRDKEKEK-EQDKEKEREKDRSKEIDE 469
Query: 511 R-------------HRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 557
+ + ASR RERR R + + +S R++ + +S S R
Sbjct: 470 KRKKDKKSRTPPRSYNASRRSRSSSRERR-RRRSRSSSRSPRTSKTIKRKSSRSPSPRSR 528
Query: 558 KHKKSKRSKEGKEAGSEPAPEQEST 582
K KR KE ++ SE + ST
Sbjct: 529 NKKDKKREKE-RDHISERRERERST 552
Score = 67.0 bits (162), Expect = 5e-11
Identities = 38/146 (26%), Positives = 74/146 (50%), Gaps = 21/146 (14%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
+EKDR++ER+R++ER+++++R + + R++ERE+D + +++R R RE +
Sbjct: 391 KEKDREKEREREKEREKEKERGKNKDRDKEREKDREK-----DKEKDRERERE------K 439
Query: 511 RHRASREKEERHRERRHREKEETR----------HKSSRSNSRRRHESEEGDSHRRHKHK 560
H R+KE+ + + +E+E+ R K SR+ R + S S R + +
Sbjct: 440 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 499
Query: 561 KSKRSKEGKEAGSEPAPEQESTEATP 586
+ RS S+ + S +P
Sbjct: 500 RRSRSSSRSPRTSKTIKRKSSRSPSP 525
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/114 (31%), Positives = 68/114 (59%), Gaps = 11/114 (9%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 509
+R+ R++ ++++R +++DR++ERER +ERE+E++ N D ++ R ++ E+
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK-----NKDRDKEREKD-REKDK 429
Query: 510 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563
E+ R RE+E+ H + R +EKE+ + K R E +E +R K KKS+
Sbjct: 430 EKDR-EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE----KRKKDKKSR 478
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 3/136 (2%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
+ K R R +R R R +DR R + ++R + R+ + S +S ++R RE +
Sbjct: 330 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 389
Query: 511 RHRASREKEERHRERRHREKEETRHK---SSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
REKE + R +EKE ++K R R + + ++ + R +H+K + ++
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 568 GKEAGSEPAPEQESTE 583
KE E E++ ++
Sbjct: 450 EKEQDKEKEREKDRSK 465
Score = 61.2 bits (147), Expect = 3e-09
Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 30/162 (18%)
Query: 452 EKDRDRERDR--DRERDRDRDRERERTRERERERDHSPTPSVFN-------SDEERYRYR 502
EKDRD+E+++ D+E++R++DR +E +R++++ P +N S ER R R
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 501
Query: 503 EYAE--------------------RGYERHRASREKEERH-RERRHREKEETRHKSSRSN 541
+ R + REKE H ERR RE+ + KSS
Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 561
Query: 542 SRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
+ + S + +H K S KE + AP E +
Sbjct: 562 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/133 (23%), Positives = 58/133 (43%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
R + +DR R + + R + RER ++R R RD ++ER + ++ +
Sbjct: 342 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 401
Query: 511 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 570
+EKE + R +E+E+ R K + R E E + K K+ + KE ++
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461
Query: 571 AGSEPAPEQESTE 583
S+ E+ +
Sbjct: 462 DRSKEIDEKRKKD 474
Score = 57.8 bits (138), Expect = 3e-08
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 10/121 (8%)
Query: 448 YARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAER 507
+ +R K R+R + R R RD+ R+ TRE+ +E++ V D E+ R RE ER
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDK---RKDTREKIKEKER-----VKEKDREKERERE-KER 405
Query: 508 GYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
E+ R + ++ RE+ R ++KE+ R + + + E+ + K ++ RSK
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465
Query: 567 E 567
E
Sbjct: 466 E 466
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 75.5 bits (184), Expect = 1e-13
Identities = 49/153 (32%), Positives = 75/153 (49%), Gaps = 27/153 (17%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
D ++ D +EKDR+RER+++ E+DRD+++E+E+ +E+ERE+D S DE+R
Sbjct: 302 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-----EIDEKRK 356
Query: 500 RYRE--YAERGYERHRASREKEERHRERRHREKEET-------RHKSSRSNS-------- 542
+ ++ R Y R SR R RR R + + KSSRS S
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 416
Query: 543 -----RRRHESEEGDSHRRHKHKKSKRSKEGKE 570
R H SE + R +KS ++GKE
Sbjct: 417 KKREKERDHISERRERERSTSMRKSSNDRDGKE 449
Score = 68.2 bits (165), Expect = 2e-11
Identities = 39/143 (27%), Positives = 77/143 (53%), Gaps = 14/143 (9%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
R K++DRE++R+RE++R++++ER + ++R++ER+ D ER R +E+ E+ +
Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK-EKDREREREKEH-EKDRD 330
Query: 511 RHRASREKEERHRER-RHREKEETRHKSSRS-------NSRRRHESEEGDSHRRHKHKKS 562
+ + + +E+ RE+ R +E +E R K +S N+ RR S + RR S
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 390
Query: 563 KRSKEGK----EAGSEPAPEQES 581
+ + K ++ P+P +
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRN 413
Score = 67.4 bits (163), Expect = 4e-11
Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 18/145 (12%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
+ KDRD+ER++DRE+D+++DRERER E+E E+D D+E+ R ++ ++ E
Sbjct: 297 KNKDRDKEREKDREKDKEKDRERER--EKEHEKDRDKEKEK-EQDKEKEREKDRSKEIDE 353
Query: 511 R-------------HRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 557
+ + ASR RERR R + + +S R++ + +S S R
Sbjct: 354 KRKKDKKSRTPPRSYNASRRSRSSSRERR-RRRSRSSSRSPRTSKTIKRKSSRSPSPRSR 412
Query: 558 KHKKSKRSKEGKEAGSEPAPEQEST 582
K KR KE ++ SE + ST
Sbjct: 413 NKKDKKREKE-RDHISERRERERST 436
Score = 67.0 bits (162), Expect = 5e-11
Identities = 38/146 (26%), Positives = 74/146 (50%), Gaps = 21/146 (14%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
+EKDR++ER+R++ER+++++R + + R++ERE+D + +++R R RE +
Sbjct: 275 KEKDREKEREREKEREKEKERGKNKDRDKEREKDREK-----DKEKDRERERE------K 323
Query: 511 RHRASREKEERHRERRHREKEETR----------HKSSRSNSRRRHESEEGDSHRRHKHK 560
H R+KE+ + + +E+E+ R K SR+ R + S S R + +
Sbjct: 324 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 383
Query: 561 KSKRSKEGKEAGSEPAPEQESTEATP 586
+ RS S+ + S +P
Sbjct: 384 RRSRSSSRSPRTSKTIKRKSSRSPSP 409
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/114 (31%), Positives = 68/114 (59%), Gaps = 11/114 (9%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 509
+R+ R++ ++++R +++DR++ERER +ERE+E++ N D ++ R ++ E+
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK-----NKDRDKEREKD-REKDK 313
Query: 510 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563
E+ R RE+E+ H + R +EKE+ + K R E +E +R K KKS+
Sbjct: 314 EKDR-EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE----KRKKDKKSR 362
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 3/136 (2%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
+ K R R +R R R +DR R + ++R + R+ + S +S ++R RE +
Sbjct: 214 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 273
Query: 511 RHRASREKEERHRERRHREKEETRHK---SSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
REKE + R +EKE ++K R R + + ++ + R +H+K + ++
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 568 GKEAGSEPAPEQESTE 583
KE E E++ ++
Sbjct: 334 EKEQDKEKEREKDRSK 349
Score = 61.2 bits (147), Expect = 3e-09
Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 30/162 (18%)
Query: 452 EKDRDRERDR--DRERDRDRDRERERTRERERERDHSPTPSVFN-------SDEERYRYR 502
EKDRD+E+++ D+E++R++DR +E +R++++ P +N S ER R R
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 385
Query: 503 EYAE--------------------RGYERHRASREKEERH-RERRHREKEETRHKSSRSN 541
+ R + REKE H ERR RE+ + KSS
Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 445
Query: 542 SRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
+ + S + +H K S KE + AP E +
Sbjct: 446 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/133 (23%), Positives = 58/133 (43%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
R + +DR R + + R + RER ++R R RD ++ER + ++ +
Sbjct: 226 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 285
Query: 511 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 570
+EKE + R +E+E+ R K + R E E + K K+ + KE ++
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345
Query: 571 AGSEPAPEQESTE 583
S+ E+ +
Sbjct: 346 DRSKEIDEKRKKD 358
Score = 57.8 bits (138), Expect = 3e-08
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 10/121 (8%)
Query: 448 YARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAER 507
+ +R K R+R + R R RD+ R+ TRE+ +E++ V D E+ R RE ER
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDK---RKDTREKIKEKER-----VKEKDREKERERE-KER 289
Query: 508 GYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
E+ R + ++ RE+ R ++KE+ R + + + E+ + K ++ RSK
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349
Query: 567 E 567
E
Sbjct: 350 E 350
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 74.3 bits (181), Expect = 3e-13
Identities = 77/248 (31%), Positives = 114/248 (45%), Gaps = 52/248 (20%)
Query: 351 PTHLPPPPFLPPPPTVSTAPPL--IPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSS 408
P++L P PF P + + L + P PI P PG+ PP L P+ H S
Sbjct: 148 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPI--------PTPGSLPP-LHPSAMHLHLS 198
Query: 409 GYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRD 468
G R + ++A H + L Q D RRE++R+RER+R+RE DR+
Sbjct: 199 GV--RYPPELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADRE 252
Query: 469 RDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRH 527
R++ERER RE+ERE+ ++ER R +E RE+E ER RE+R
Sbjct: 253 REKEREREREKEREQ-----------EKEREREKE------------RERELERQREQRA 289
Query: 528 REKEETRHKS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPE 578
REKE K+ + + R H +EE + + R+++ K+AG + P P
Sbjct: 290 REKELLAAKALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPV 347
Query: 579 QESTEATP 586
Q P
Sbjct: 348 QHPLHPVP 355
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 74.3 bits (181), Expect = 3e-13
Identities = 77/248 (31%), Positives = 114/248 (45%), Gaps = 52/248 (20%)
Query: 351 PTHLPPPPFLPPPPTVSTAPPL--IPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSS 408
P++L P PF P + + L + P PI P PG+ PP L P+ H S
Sbjct: 252 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPI--------PTPGSLPP-LHPSAMHLHLS 302
Query: 409 GYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRD 468
G R + ++A H + L Q D RRE++R+RER+R+RE DR+
Sbjct: 303 GV--RYPPELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADRE 356
Query: 469 RDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRH 527
R++ERER RE+ERE+ ++ER R +E RE+E ER RE+R
Sbjct: 357 REKEREREREKEREQ-----------EKEREREKE------------RERELERQREQRA 393
Query: 528 REKEETRHKS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPE 578
REKE K+ + + R H +EE + + R+++ K+AG + P P
Sbjct: 394 REKELLAAKALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPV 451
Query: 579 QESTEATP 586
Q P
Sbjct: 452 QHPLHPVP 459
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 73.9 bits (180), Expect = 4e-13
Identities = 67/242 (27%), Positives = 97/242 (40%), Gaps = 65/242 (26%)
Query: 339 SKPPPFFPPGAPPTHLPPPPFLPPPPTVST------------------------------ 368
++PP PP PP LPPPP + P T +
Sbjct: 1540 TRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSET 1599
Query: 369 ----APPLIPPPGIPITVPPPGFPP---PPGAPPPSLIPTIESGHSSGYDSRSARAFPYG 421
+ P++PPP + ++PPPG P PP + PP + T++ GH + PYG
Sbjct: 1600 AAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYG 1659
Query: 422 NVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERER 481
P P + E + +RDR DR+RDRE R+
Sbjct: 1660 E-RITLRPDPLPERSTF-------------ETEHAGQRDR---YDRERDREPYFDRQSNV 1702
Query: 482 ERDHSPTPSVFNSDEERYRYREYAERG---YERHRASREKEER-HRERRHREKEETRHKS 537
DH F D E +R R+ +RG Y+R R RE+ R R + +R+K++ H S
Sbjct: 1703 IADHRD----FKRDRETHRDRD-RDRGVIDYDRDRFDRERRPRDDRAQSYRDKKD--HSS 1755
Query: 538 SR 539
SR
Sbjct: 1756 SR 1757
Score = 69.3 bits (168), Expect = 9e-12
Identities = 33/75 (44%), Positives = 40/75 (53%), Gaps = 10/75 (13%)
Query: 337 NFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPP------- 389
N S PPPF P P PP P +PPP + PP + PP +P TVPPPG PP
Sbjct: 513 NMSMPPPFVPYSQMP---PPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSL 569
Query: 390 PPGAPPPSLIPTIES 404
P PPP + P++ S
Sbjct: 570 PTSVPPPGMPPSLSS 584
Score = 66.6 bits (161), Expect = 6e-11
Identities = 56/180 (31%), Positives = 86/180 (47%), Gaps = 30/180 (16%)
Query: 354 LPPPPFLPPPPTVSTAPPLIPPPG-IPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDS 412
+P P LPPPP S+ IPPPG +P+ +PP PPP + T++ GH +
Sbjct: 1602 IPSAPVLPPPPVHSS----IPPPGPVPMGMPPMSKPPP-------VQQTVDYGHGRDIST 1650
Query: 413 RSARAFPYGNVAFPHLPGSAPSWPSL-VDTSKQWDYYARREKDRDRERDRDRERD----- 466
PYG P P + + + Q D Y +++RDRE DR+ +
Sbjct: 1651 NKVEQIPYGE-RITLRPDPLPERSTFETEHAGQRDRY---DRERDREPYFDRQSNVIADH 1706
Query: 467 RDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERR 526
RD R+RE R+R+R+R V + D +R+ RE R +R ++ R+K++ RR
Sbjct: 1707 RDFKRDRETHRDRDRDR------GVIDYDRDRFD-RERRPRD-DRAQSYRDKKDHSSSRR 1758
Score = 63.2 bits (152), Expect = 7e-10
Identities = 46/114 (40%), Positives = 52/114 (45%), Gaps = 23/114 (20%)
Query: 339 SKPPPFFPPG----APPTHLPPP--------PFLPPPPTVSTAPP-LIPPPGIPITVPPP 385
S PPP PP PP LPPP P LPPP STAPP ++P P + PPP
Sbjct: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPP 631
Query: 386 GFPPP--PGAPPPSL----IPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAP 433
G PPP P PP L +P S SS + A V+F GSAP
Sbjct: 632 GIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF----GSAP 681
Score = 60.5 bits (145), Expect = 4e-09
Identities = 39/105 (37%), Positives = 51/105 (48%), Gaps = 13/105 (12%)
Query: 307 TISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLP--PPPFLPP-- 362
T S ++ + + +N Q + S +S+ PP P PP P PPP +PP
Sbjct: 492 TQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPAL 551
Query: 363 PPTVST--APPLIPPPGIPITVPPPGFP-------PPPGAPPPSL 398
P TV PP + PP +P +VPPPG P PPP PPPSL
Sbjct: 552 PATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSL 596
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/132 (27%), Positives = 49/132 (37%), Gaps = 39/132 (29%)
Query: 341 PPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPP--------------- 385
PPP PP + + PPP PP + +T PP IPPPG+P +PP
Sbjct: 601 PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSS 660
Query: 386 -----------------GFPPPPGAPPPSLIPTIESGHSSGYDSR---SARAFPYGNVAF 425
G PP P P +G S +S+ S A PY + +
Sbjct: 661 QVPEKPRPALLPTPVSFGSAPPTTYHP----PLQSAGPSEQVNSKAPLSKSALPYSSFSS 716
Query: 426 PHLPGSAPSWPS 437
G + + PS
Sbjct: 717 DQGLGESSAAPS 728
Score = 44.3 bits (103), Expect = 3e-04
Identities = 42/149 (28%), Positives = 56/149 (37%), Gaps = 52/149 (34%)
Query: 341 PPPFFPPGAPPTHLPPPPFLPPPPTVSTA-------------------PPLIP------- 374
PPP P G PPPP +PPPP + + P L+P
Sbjct: 88 PPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPP 147
Query: 375 -----PPG---------IPITVPPPGFPP--------PPGAPPPSLIPTIES--GHSSGY 410
PPG +P PPP + P PP P PS P +S + Y
Sbjct: 148 ESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSY 207
Query: 411 DSRSARAFPYGNVAFPHLPGS--APSWPS 437
S S+ + Y + + +LP S +PS PS
Sbjct: 208 SSSSSSSQSYLSHSQSYLPSSQASPSRPS 236
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 21/129 (16%)
Query: 445 WDYYARREKDRDRERDRDRERDRDRDRE----------RERTRERERERDHSPTPSVFNS 494
WD + E+D+D + D +RE +RD DR+ +R+ + E +RD+ +
Sbjct: 1265 WDDW---ERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYG---RPLDE 1318
Query: 495 DEERYRYREYAERG-----YERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESE 549
E ++R R+ R +++R RE R+RE R R R R E
Sbjct: 1319 QESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPE 1378
Query: 550 EGDSHRRHK 558
GD+ R +
Sbjct: 1379 RGDTWREKR 1387
Score = 39.7 bits (91), Expect = 0.008
Identities = 22/43 (51%), Positives = 24/43 (55%), Gaps = 9/43 (20%)
Query: 351 PTHLPPPPFLPPPPTVSTAPPLIPPPGI-PITVPPPGFPPPPG 392
P HLPPPP LPP PP++P G PPP PPPPG
Sbjct: 78 PHHLPPPP-LPP-------PPVMPGGGYGDWQPPPPPMPPPPG 112
Score = 32.3 bits (72), Expect = 1.2
Identities = 22/84 (26%), Positives = 26/84 (30%), Gaps = 37/84 (44%)
Query: 352 THLPPPPFLPPPPTVSTAPPLIPPPGIPITVPP--------------------------- 384
+H PPPP PPPP P P PG + P
Sbjct: 12 SHYPPPPVPPPPPV--ALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69
Query: 385 --------PGFPPPPGAPPPSLIP 400
P PPP PPP ++P
Sbjct: 70 KQMQCVLQPHHLPPPPLPPPPVMP 93
Score = 32.3 bits (72), Expect = 1.2
Identities = 29/107 (27%), Positives = 40/107 (37%), Gaps = 38/107 (35%)
Query: 346 PPGAPPTHLPPP---PFLPPP-PTVSTAPP----LIPPPG------------------IP 379
PP PP++ PP P+LPP P+ S +PP L P P +P
Sbjct: 167 PPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLP 226
Query: 380 ITVPPPG------------FPPPPGAPPPSLIPTIESGHSSGYDSRS 414
+ P PPPP APP + + SG ++S
Sbjct: 227 SSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKS 273
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 72.0 bits (175), Expect = 1e-12
Identities = 45/131 (34%), Positives = 71/131 (54%), Gaps = 10/131 (7%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDR------DRDRERERTRERERERDHSPTPSVFN 493
D + + RE+ RDR+R++DRER R D+DRE E ++R+RER+ T +
Sbjct: 115 DRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD 174
Query: 494 SDEERYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGD 552
+ ER + RE R +R R REKE+R R+R R +E+E+ R++ R R R + + +
Sbjct: 175 RERERQKQRE-TRRDRDRER-QREKEDRERDRDRQKEREKDRYR-ERETGRDRDKERDRE 231
Query: 553 SHRRHKHKKSK 563
R + K
Sbjct: 232 RQREKDRDRQK 242
Score = 71.6 bits (174), Expect = 2e-12
Identities = 44/149 (29%), Positives = 76/149 (51%), Gaps = 16/149 (10%)
Query: 440 DTSKQWDYYARREKDRDR------ERDRDRERDRDRDRERERTRERERERDHSPTPSV-- 491
D ++ D +R +DRDR +RDR+ E +R +RER+R R+RE++R+ +
Sbjct: 89 DRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGI 148
Query: 492 -----FNSDEERYRYREYAERGYERHR-ASREKEERHRERRHREKEETRHKSSRSNSRRR 545
++++R R RE E ER+R RE++++ RR R++E R K R R R
Sbjct: 149 DKDREIETEKDRDREREMGET--ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDR 206
Query: 546 HESEEGDSHRRHKHKKSKRSKEGKEAGSE 574
+ E D +R + + + + +E E
Sbjct: 207 QKEREKDRYRERETGRDRDKERDRERQRE 235
Score = 69.3 bits (168), Expect = 9e-12
Identities = 43/166 (25%), Positives = 81/166 (48%), Gaps = 14/166 (8%)
Query: 428 LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP 487
L GS + + + +Q + +R++ ++R R++DRE ++DRDR+R+R RER+R RD
Sbjct: 47 LRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDR 106
Query: 488 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRER-------------RHREKEETR 534
+ + ER +R R + ER R+R + R++E
Sbjct: 107 KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREM 166
Query: 535 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 580
++ R R R ++ ++ RR + ++ +R KE +E + E+E
Sbjct: 167 GETERYRDRERERQKQRET-RRDRDRERQREKEDRERDRDRQKERE 211
Score = 68.9 bits (167), Expect = 1e-11
Identities = 49/149 (32%), Positives = 69/149 (46%), Gaps = 24/149 (16%)
Query: 451 REKDRDRERDRDRER--------DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 502
R++ RDRER R R+R DRDR+ E ER ERER+RD D ER R R
Sbjct: 90 RQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKR-----EKDRERQRQR 144
Query: 503 EY---------AERGYERHRASREKEE-RHRERRHREKEETRHKSSRSNSRRRHESEEGD 552
E E+ +R R E E R RER +++ ETR R R + + E
Sbjct: 145 EIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDR 204
Query: 553 SHRRHKHKKSKRSKE-GKEAGSEPAPEQE 580
++ + K R +E G++ E E++
Sbjct: 205 DRQKEREKDRYRERETGRDRDKERDRERQ 233
Score = 63.2 bits (152), Expect = 7e-10
Identities = 32/87 (36%), Positives = 49/87 (56%), Gaps = 1/87 (1%)
Query: 452 EKDRDRERDR-DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
EKDRDRER+ + ER RDR+RER++ RE R+RD + + +R R +E + Y
Sbjct: 157 EKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYR 216
Query: 511 RHRASREKEERHRERRHREKEETRHKS 537
R++++ R REK+ R K+
Sbjct: 217 ERETGRDRDKERDRERQREKDRDRQKA 243
Score = 62.4 bits (150), Expect = 1e-09
Identities = 41/151 (27%), Positives = 72/151 (47%), Gaps = 25/151 (16%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYRE------- 503
RE++R RER+R R+R ++R RE++R E++R+R D ER R+R+
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRK-------RDRERQRWRDRDRKRER 110
Query: 504 --------YAERGYERHRASREKEERHRERRHREK---EETRHKSSRSNSRRRHESEEGD 552
ER ER R K E+ RER+ + + ++ R + + R E E +
Sbjct: 111 WGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETE 170
Query: 553 SHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
+R + ++ K+ + ++ E E+E E
Sbjct: 171 RYRDRERERQKQRETRRDRDRERQREKEDRE 201
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/50 (46%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Query: 440 DTSKQWDYYARREKDRDRERD--RDRERDRDRDRERERTRERERERDHSP 487
D + D REKDR RER+ RDR+++RDR+R+RE+ R+R++ D P
Sbjct: 199 DRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAIDCVP 248
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 71.6 bits (174), Expect = 2e-12
Identities = 32/63 (50%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Query: 341 PPPFFPPGAPPTHLPPP-PFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLI 399
PPP FPP PP PPP P P PP + PP PP +TVPPP P PPG PPP ++
Sbjct: 683 PPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPIL 742
Query: 400 PTI 402
P +
Sbjct: 743 PPL 745
Score = 57.4 bits (137), Expect = 4e-08
Identities = 34/67 (50%), Positives = 39/67 (58%), Gaps = 8/67 (11%)
Query: 341 PPPFFPPGAP-PTHLPPPPFLPPP--PTVSTAPPLIP-PPGIPITVPPPGFPPPPGAPPP 396
PPP PG P P LPPPP PPP P V+ PP +P PPG+P PPP PP P PP
Sbjct: 695 PPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVP---PPPILPPLPPF-PP 750
Query: 397 SLIPTIE 403
L P ++
Sbjct: 751 GLFPVMQ 757
Score = 50.1 bits (118), Expect = 6e-06
Identities = 26/52 (50%), Positives = 28/52 (53%), Gaps = 4/52 (7%)
Query: 338 FSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPP 389
F PPP PP PP P +PPPP APP +PPP PI P P FPP
Sbjct: 703 FPMPPPLPPPPPPPPPAHPAVTVPPPPL--PAPPGVPPP--PILPPLPPFPP 750
Score = 40.8 bits (94), Expect = 0.004
Identities = 34/112 (30%), Positives = 43/112 (38%), Gaps = 32/112 (28%)
Query: 341 PPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPP--PGF----------- 387
P P PP PP PP P P T + P +PP + PP PG
Sbjct: 1275 PLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTE 1334
Query: 388 --PPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPS 437
P PG PP SG SSG +++ P +PGS S+P+
Sbjct: 1335 TVPATPGGEPPL------SGGSSGL-----------SLSSPQVPGSPFSYPA 1369
Score = 40.0 bits (92), Expect = 0.006
Identities = 45/212 (21%), Positives = 70/212 (33%), Gaps = 15/212 (7%)
Query: 388 PPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDY 447
P P L+ + G GY+ G + P P DT+ D
Sbjct: 922 PKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPP---DTTSSGDQ 978
Query: 448 YARREKDRDRERDRDRERDRDRD----------RERERTRERERERDHSPTPSVFNSDEE 497
R E D + ER+RDRD R+ + R R S DE+
Sbjct: 979 KRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEK 1038
Query: 498 RYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 557
E E E+EE + +++E+ + + E +EGDS
Sbjct: 1039 ESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEE 1098
Query: 558 KHK--KSKRSKEGKEAGSEPAPEQESTEATPA 587
SK SE + + S+E++P+
Sbjct: 1099 TVSIVTSKAEATSSSESSESSEFESSSESSPS 1130
Score = 38.5 bits (88), Expect = 0.017
Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 347 PGAPPTHLP-PPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESG 405
P AP T P P + P + A P + P +P+ PPPGFPP PPP P + G
Sbjct: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP-PPPGFPP---LPPPPPPPPPQPG 702
Score = 36.6 bits (83), Expect = 0.066
Identities = 47/174 (27%), Positives = 58/174 (33%), Gaps = 40/174 (22%)
Query: 256 SRNSTSSQ--SQTSTASRKANSSVGKWQDRYGRAE-------SPDLRRLPGAIDVI-GQT 305
SR T S SQ + KA K+ D Y R SP + + GA G +
Sbjct: 291 SRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSS 350
Query: 306 ITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPP------------FFPPGAPPTH 353
G + + + SAT PPP F P P H
Sbjct: 351 DLPFGAVGGTGGSSGPPFKAQPQDSATFAHT----PPPAQATPAPGFKSAFSPYQTPVAH 406
Query: 354 LPPPPFLPPPPTV-----------STAPPLIPPPGIPITVPPPGFPPPPGAPPP 396
PPPP P + APP +PP P+ PG PP G PPP
Sbjct: 407 FPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAE-PLAKEKPGTPP--GPPPP 457
Score = 35.8 bits (81), Expect = 0.11
Identities = 42/163 (25%), Positives = 54/163 (33%), Gaps = 30/163 (18%)
Query: 351 PTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPP-------PGFPPP------------P 391
PT LPP L P P S PP+ PG P PP P PP P
Sbjct: 1454 PTPLPP---LLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLP 1510
Query: 392 GAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDT-------SKQ 444
G P + P+ + D R+A P P P P P + T Q
Sbjct: 1511 GQPQTPVFPSTHDPRTVTLDFRNA-GIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQ 1569
Query: 445 WDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP 487
W A R R+ + + + R R ++R D P
Sbjct: 1570 WPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVP 1612
Score = 33.9 bits (76), Expect = 0.43
Identities = 19/52 (36%), Positives = 22/52 (42%)
Query: 347 PGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSL 398
PG P T + P P T+ IP P P+ PP PPPP P L
Sbjct: 1510 PGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKL 1561
Score = 32.0 bits (71), Expect = 1.6
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 6/72 (8%)
Query: 12 ELSGGTGGDE-----EEEWLYGDENEVERPEEENASANPPSGIEDETAENGVPKPKVTET 66
EL G DE EE+ +E E E EEE + S DE+ EN ++E
Sbjct: 1028 ELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDES-ENDDEDTALSEA 1086
Query: 67 EDDSDSDSDDDE 78
+ + DSD++E
Sbjct: 1087 SEKDEGDSDEEE 1098
Score = 30.4 bits (67), Expect = 4.7
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 6/46 (13%)
Query: 34 ERPEEENASANPPSGIEDETAENGVPKPKVTETEDDSDSDSDDDED 79
E E+E+ S S E+E AE + E EDD D DSDD ++
Sbjct: 1034 EEDEKESLSEEQESTEEEEEAE------EEEEEEDDDDDDSDDRDE 1073
Score = 30.0 bits (66), Expect = 6.2
Identities = 22/63 (34%), Positives = 25/63 (39%), Gaps = 8/63 (12%)
Query: 329 RSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFP 388
R+ T N P P PP PP PPP PPPP P +P + P P
Sbjct: 1525 RTVTLDFRNAGIPAP--PPPLPPQPPPPP---PPPP---VEPTKLPFKELDNQWPSEAIP 1576
Query: 389 PPP 391
P P
Sbjct: 1577 PGP 1579
Score = 29.6 bits (65), Expect = 8.1
Identities = 32/147 (21%), Positives = 46/147 (31%), Gaps = 9/147 (6%)
Query: 450 RREKDRDRERDRDRERD--------RDRDRERERTRERERERDHSPTPSVFNSDEERYRY 501
RR R E D E D ++ E E E E E D S + E
Sbjct: 1020 RRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE 1079
Query: 502 REYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKK 561
E+ ++EE + E T S +S SE S + +
Sbjct: 1080 DTALSEASEKDEGDSDEEETVSIVTSK-AEATSSSESSESSEFESSSESSPSSSEDEEEV 1138
Query: 562 SKRSKEGKEAGSEPAPEQESTEATPAE 588
R +E +E E E+ A P +
Sbjct: 1139 VAREEEEEEEEEEMVAEESMASAGPED 1165
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 3/154 (1%)
Query: 429 PGSAPSWPSLVDTSKQWDYYARRE--KDRDRERDRDRERDRDRDRERERTRERERERDHS 486
P + P W S + ++ + R+E K+R+ ER ++R R RERE+ R+RER +
Sbjct: 28 PCTQPGWQSEI-REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
Query: 487 PTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRH 546
E + R RE + E ++KE++ R R +E +E K R R+
Sbjct: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
Query: 547 ESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 580
+ + + + +K ++ +E K+ G + +E
Sbjct: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Score = 66.6 bits (161), Expect = 6e-11
Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 9/130 (6%)
Query: 442 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRY 501
+K+ + +R+K +ER R + ++R+R+ ER RE +ER+ EER +
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE--------RKKEEREKE 157
Query: 502 REYAERGYERHRASREKEERHRERRHRE-KEETRHKSSRSNSRRRHESEEGDSHRRHKHK 560
RE ER + EKEE +E+ +E K+ R++ R R R E E R+ K +
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEE 217
Query: 561 KSKRSKEGKE 570
+ K ++ ++
Sbjct: 218 RKKERQKDRQ 227
Score = 66.2 bits (160), Expect = 8e-11
Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 449 ARREKDRDRERDRDRERDRDRDRER-ERTRERER-ERDHSPTPSVFNSDEERYRYREYAE 506
++ K+R+R+ +R RE ++R+R++ ER +ERER ER V +EER
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 507 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
+ ER+R R+KE +ERR R+KE + K R R++ R K ++ +R K
Sbjct: 187 KKRERNRKERKKERERKERRERKKER-KKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 63.2 bits (152), Expect = 7e-10
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 509
++E+ R + ++RER +R RE + RER++E ER + E E
Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179
Query: 510 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE-G 568
E+ R R+K ER+R+ R +E+E K R + R + EE R+ + + R KE G
Sbjct: 180 EKERKERKKRERNRKERKKERE---RKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Query: 569 KEAGSE 574
K E
Sbjct: 237 KRERKE 242
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
+ K+ + R++++R + +++ ER +ER++ +ER +ER
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER-----------KKERE 201
Query: 500 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRR 544
R +E ER ER + K+ER ++R+ +E+ R K R ++
Sbjct: 202 R-KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 70.5 bits (171), Expect = 4e-12
Identities = 46/149 (30%), Positives = 75/149 (50%), Gaps = 16/149 (10%)
Query: 450 RREKDRDRERDRDRERDRDRD-------RERERTRERERERDHSPTPSVFNSDEER---- 498
RRE+++ R+R+R++ER R+R ++RER +ERER+R ++ER
Sbjct: 40 RREREK-RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
Query: 499 --YRYREYAERGYERHRASREKEERHRERRHR--EKEETRHKSSRSNSRRRHESEEGDSH 554
+ RE +RG + +E++ER RE + R K + R K R R+R +
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158
Query: 555 RRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
+R K KK +R K+ + E E+E E
Sbjct: 159 KRKKRKKEEREKKRERNRKERKKERERKE 187
Score = 68.9 bits (167), Expect = 1e-11
Identities = 35/122 (28%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERER-ERDHSPTPSVFNSDEERYRYREYAERG 508
RREK+R + + ++R+R + RER +++ER ER+ ++R + + ER
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 509 YERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEG 568
E+ R RE++ + R++ REK+ R++ R R R E E R+ + +K K K+
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Query: 569 KE 570
++
Sbjct: 209 RK 210
Score = 67.4 bits (163), Expect = 4e-11
Identities = 43/122 (35%), Positives = 66/122 (54%), Gaps = 6/122 (4%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAER-- 507
+RE +R +ER R+RE+ R R+RE+ER RER ++ + ER R +R
Sbjct: 31 QRESERKKER-REREK-RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE 88
Query: 508 GYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
E+ R R+KE++ RER+ R + E + K R R E+++ +R K +K KR KE
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKER--KERERENKQRRERKRKKRRKKKRRKE 146
Query: 568 GK 569
K
Sbjct: 147 RK 148
Score = 65.5 bits (158), Expect = 1e-10
Identities = 36/137 (26%), Positives = 66/137 (48%), Gaps = 4/137 (2%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
REK R R+++R + + ++RER + RER + ++ R R+ +R +
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
Query: 511 RHRASREKEE----RHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
+ R R++E+ R R+R+ R+KEE K R+ R+ E E + R K +K +R K
Sbjct: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Query: 567 EGKEAGSEPAPEQESTE 583
+ + Q ++
Sbjct: 202 KKERKKDRKTDRQTDSQ 218
Score = 63.9 bits (154), Expect = 4e-10
Identities = 41/125 (32%), Positives = 65/125 (52%), Gaps = 17/125 (13%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 509
RRE+ + +ER ++RER+ + RER+R + R+++R +ER R +E +R
Sbjct: 111 RRERKKKKER-KERERENKQRRERKRKKRRKKKRR-----------KERKREKERGKR-- 156
Query: 510 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGK 569
ER R R+KEER ++R KE K R RR +E RR K ++ K K +
Sbjct: 157 ERKRKKRKKEEREKKRERNRKE---RKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
Query: 570 EAGSE 574
+ S+
Sbjct: 214 QTDSQ 218
Score = 60.8 bits (146), Expect = 3e-09
Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 4/114 (3%)
Query: 461 RDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEE 520
R+ ER ++R +R RERE+ER ++R R +E + ER + +E+ E
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 521 RHRERRHREKEETRHKS----SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 570
+ R +R +EK++ K R + R E E + RR + +K +R K+ ++
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Score = 58.2 bits (139), Expect = 2e-08
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 9/120 (7%)
Query: 464 ERDRDRDRE------RERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASRE 517
+R+ +R +E R+R RE+ER+R+ ER + RE + E+ R R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 518 KEERHRERRHREKEETRHKSSRSNSRRRHESE---EGDSHRRHKHKKSKRSKEGKEAGSE 574
++ER + ++ ++K E + + R +++ E E R K KK ++ K KE E
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Score = 37.0 bits (84), Expect = 0.051
Identities = 16/56 (28%), Positives = 29/56 (51%)
Query: 515 SREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 570
++ + ER +ERR REK + + R R + E ++ R K ++ KR + K+
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Score = 32.0 bits (71), Expect = 1.6
Identities = 14/66 (21%), Positives = 30/66 (45%)
Query: 515 SREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE 574
S+ +R ER+ +E + K R R+R ++ R+ + + +R ++ KE +
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Query: 575 PAPEQE 580
+E
Sbjct: 86 RKERRE 91
Score = 30.4 bits (67), Expect = 4.7
Identities = 10/41 (24%), Positives = 28/41 (68%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERE 480
+ K+ + RRE+ ++R+++R ++++R +DR+ +R + +
Sbjct: 178 ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo
sapiens]
Length = 1792
Score = 68.9 bits (167), Expect = 1e-11
Identities = 69/282 (24%), Positives = 107/282 (37%), Gaps = 56/282 (19%)
Query: 327 SERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIP--------PPGI 378
SERS + P F P +PPPP PPPP PP +P PPG
Sbjct: 539 SERSQRTQGPSLPATPVFVP-------VPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQ 591
Query: 379 P----ITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPS 434
P +VPPPGFPP AP P + SG + + + + P+
Sbjct: 592 PPPAGYSVPPPGFPP---APANLSTPWVSSGVQTAHSN------------------TIPT 630
Query: 435 WPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRE----RERTRERERERDHSPTP- 489
+ + +++ RR K+ ++++ + E D +E ++ +ER R S +P
Sbjct: 631 TQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPY 690
Query: 490 --SVFNSDEERY--------RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSR 539
S ++ Y R R Y+ R + R + RR R K SR
Sbjct: 691 SGSSYSRSSYTYSKSRSGSTRSRSYS-RSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSR 749
Query: 540 SNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQES 581
S+ R S R H +S ++ G+ P+ E+
Sbjct: 750 SHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGET 791
Score = 39.3 bits (90), Expect = 0.010
Identities = 25/105 (23%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
Query: 481 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEE-TRHKSSR 539
R + HS +PSV S + R + +S E ++ ++++ +EK++ +HK +
Sbjct: 1689 RNQSHS-SPSV--SPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHK 1745
Query: 540 SNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA 584
+ + E + ++HKHKK K+SK+ K+ E + + ++
Sbjct: 1746 KHKKHAGTEVELEKSQKHKHKK-KKSKKNKDKEKEKEKDDQKVKS 1789
Score = 34.3 bits (77), Expect = 0.33
Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 28/161 (17%)
Query: 447 YYARREKDRDR-ERDRDRERDRDRDRERER----------TRERERERDHSPTP----SV 491
YY R RD E++R RE +R E+ R + SP ++
Sbjct: 811 YYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNI 870
Query: 492 FNSDEERYRYREYAERGYERHRA----SREKEERHRERRHREKEETRHKSSRSNSRRRHE 547
NS R R +Y G + HR+ S E+ H +K+ T+ K S E
Sbjct: 871 RNSPFTRGRREDYV--GGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKES------E 922
Query: 548 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588
+ GD + +KHKK ++ ++G+E+ PE T E
Sbjct: 923 NAPGDG-KGNKHKKHRKRRKGEESEGFLNPELLETSRKSRE 962
Score = 33.5 bits (75), Expect = 0.56
Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 21/95 (22%)
Query: 473 RERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEE 532
R + + R HS + S S + S++K+++ +++H K+
Sbjct: 1702 RSHSPSGSQTRSHSSSASSAESQD------------------SKKKKKKKEKKKH--KKH 1741
Query: 533 TRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 567
+HK + ++ E E+ H +HK KKSK++K+
Sbjct: 1742 KKHKKHKKHAGTEVELEKSQKH-KHKKKKSKKNKD 1775
Score = 30.8 bits (68), Expect = 3.6
Identities = 29/154 (18%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Query: 441 TSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 500
T ++ D A +K+ + + + D +RER E ++ TP N+
Sbjct: 1019 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSS 1078
Query: 501 YREYAERGYERHRASREKEERHRERRHREKEETRH------KSSRSNSRRRHESEEGDSH 554
++ G R S+ +E H+E + ++E+ + KS + ++ + + +
Sbjct: 1079 QKDEKITGTPRKAHSKSAKE-HQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKN 1137
Query: 555 RRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588
+ +K KR ++ +E G + E S + + E
Sbjct: 1138 KPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLE 1171
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 67.8 bits (164), Expect = 3e-11
Identities = 65/223 (29%), Positives = 91/223 (40%), Gaps = 26/223 (11%)
Query: 371 PLIPPPGIPITVPPPGFPPP------PGAPPPSLIPTIESGHS-------SGYDSRSARA 417
P + PG + P PP A PPS + + G + D R +
Sbjct: 2016 PQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGKG 2075
Query: 418 FPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTR 477
Y N F ++ D R +DR RER+R R R+RD +R R
Sbjct: 2076 HEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREW 2135
Query: 478 ERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER-RHREKEETRHK 536
+R R++D S D +R R R A R ER ++ +R RER R+RE+E R +
Sbjct: 2136 DRHRDKDSS-------RDWDRNRERS-ANRDREREADRGKEWDRSRERSRNRERERDRRR 2187
Query: 537 S-SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPE 578
RS SR R + D R K +S KE+ +P PE
Sbjct: 2188 DRDRSRSRERDRDKARDRERGRDRKDRSKS---KESARDPKPE 2227
Score = 64.7 bits (156), Expect = 2e-10
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 16/109 (14%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 499
D+S+ WD R +RDRER+ DR ++ DR RER R RERER+R D +R
Sbjct: 2142 DSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDR---------RRDRDRS 2192
Query: 500 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 548
R R ER R ER R+R+ R K + + + + R ++
Sbjct: 2193 RSR-------ERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDA 2234
Score = 58.5 bits (140), Expect = 2e-08
Identities = 41/114 (35%), Positives = 58/114 (50%), Gaps = 7/114 (6%)
Query: 442 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRY 501
S++ D+ RE DR RD+D RD DR+RER R+RERE D ++ ER R
Sbjct: 2124 SRERDWDRPREWDRH--RDKDSSRDWDRNRERSANRDREREADRG---KEWDRSRERSRN 2178
Query: 502 REYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR 555
RE ER R R ER R++ R++E R + RS S+ + ++ R
Sbjct: 2179 RE-RERDRRRDRDRSRSRERDRDKA-RDRERGRDRKDRSKSKESARDPKPEASR 2230
Score = 57.8 bits (138), Expect = 3e-08
Identities = 42/128 (32%), Positives = 62/128 (48%), Gaps = 21/128 (16%)
Query: 443 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 502
+ WD R ++ DR RD+D RD DR+RER R+RERE D ++ ER R R
Sbjct: 2127 RDWD----RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKE---WDRSRERSRNR 2179
Query: 503 EYAERGYERHRASREKEERH-RER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHK 560
E RE++ R R+R R RE++ + + R+ S+ +S R K +
Sbjct: 2180 E------------RERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPE 2227
Query: 561 KSKRSKEG 568
S+ S G
Sbjct: 2228 ASRASDAG 2235
Score = 42.4 bits (98), Expect = 0.001
Identities = 46/178 (25%), Positives = 66/178 (37%), Gaps = 32/178 (17%)
Query: 346 PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGA------------ 393
PPG+PP PPP LP PP + L P P T A
Sbjct: 1257 PPGSPP----PPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTAS 1312
Query: 394 PPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLP-----GSAPSWPSLVDTSKQWDYY 448
P ++ T+ G +D SAR P P P P+ P L +Q+ +
Sbjct: 1313 PLEHILQTL-FGKKKSFDP-SAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQF 1370
Query: 449 ARREKDRDRERDRDRERDRDRDRER-------ERTRERERERDHSPTPSVFNSDEERY 499
++ + + E DR + + + D ER ER R E ER +P + +E Y
Sbjct: 1371 SKDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVER--APEAAAAEREEVAY 1426
>gi|7662018 PHD finger protein 3 [Homo sapiens]
Length = 2039
Score = 67.4 bits (163), Expect = 4e-11
Identities = 63/231 (27%), Positives = 99/231 (42%), Gaps = 36/231 (15%)
Query: 342 PPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPIT----VPPPGFPPPPGAPPPS 397
PP FP PP P F PP PPL+PPPG VP P PG P
Sbjct: 1812 PPGFPFPGPPNFPPQSMFGFPP---HLPPPLLPPPGFGFAQNPMVPWPPVVHLPGQPQRM 1868
Query: 398 LIPTIES----GHSSGYDSRSAR------AFPYG-----NVAFPHLPGSAPSWPSLVDT- 441
+ P ++ G + Y + R + P+G + P G D+
Sbjct: 1869 MGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSH 1928
Query: 442 -------SKQWDYYARREKDRDRERDRDRER----DRDRDRERERTRERERERDHSPTPS 490
K+W+ + R + RDR +D+DR+R + +D+ER R +R D +
Sbjct: 1929 HLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD 1988
Query: 491 VFNSDEERYRYR-EYAERGYERHRASREKEERHRERRHREKEET-RHKSSR 539
N D++ + + E E+ ER ++ + E+ R+R H++++ T R KS R
Sbjct: 1989 SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
Score = 58.2 bits (139), Expect = 2e-08
Identities = 62/272 (22%), Positives = 115/272 (42%), Gaps = 53/272 (19%)
Query: 349 APPTHLPPPPFLPPPPTVS---TAPPLIPPPGIPITVPPPGFPP------PPGAPPPSLI 399
+P T P P P + ++PP P PG PP FPP PP PPP L
Sbjct: 1788 SPRTSTNFSPMRPQQPNLQHLKSSPPGFPFPG------PPNFPPQSMFGFPPHLPPPLLP 1841
Query: 400 PTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQW----DYYARREKDR 455
P G+ P+ V HLPG + + ++ ++Y ++ R
Sbjct: 1842 P-------PGFGFAQNPMVPWPPVV--HLPGQPQRMMGPLSQASRYIGPQNFYQVKDIRR 1892
Query: 456 DRERDRD---RERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH 512
R D R+ + DR R + +R+R +S + + +R R+ + E+ ERH
Sbjct: 1893 PERRHSDPWGRQDQQQLDRPFNRGK-GDRQRFYSDSHHL-----KRERHEKEWEQESERH 1946
Query: 513 R-----ASREKEERHRERRHREKEETR---------HKSSRS--NSRRRHESEEGDSHRR 556
R ++++ + RE H++KE R K+SR N ++ + + + + +
Sbjct: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006
Query: 557 HKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588
K ++ + +EG++ +++ T+ T ++
Sbjct: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 66.6 bits (161), Expect = 6e-11
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Query: 440 DTSKQWDYYARREKDRDRE----RDRDRERDRDRDRERERTRERERERDHSPTPSVFNSD 495
D S+ Y R++ R R RD R R ++ R+R R+R +ERDHS S + +
Sbjct: 436 DCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSP-SKE 494
Query: 496 EERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRR-RHESEEGDSH 554
+ R R ++ R S KE HR R KE R +S N R R +S
Sbjct: 495 RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEE 554
Query: 555 RRHKHKKSKRSKEGKEAGSEPAPEQESTEA 584
R H+ +S + + P+ E+E ++
Sbjct: 555 REHRQSRSPSKERDRRRWRSPSKERERRQS 584
Score = 59.3 bits (142), Expect = 1e-08
Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 14/172 (8%)
Query: 429 PGSAPSWPSLVDTSKQWDYYARREKDRDRE--------RDRDRERDRDRDRERERTRERE 480
P L SK+ D+ R ++R+ ++RD R R +ER+R + R
Sbjct: 479 PSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRS 538
Query: 481 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRS 540
++ + S S+E +R + +R R +ER R + EE H SRS
Sbjct: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRS 598
Query: 541 NSRRRHESEEGDSHRRHKHKKSKR-SKEGKEAGS-----EPAPEQESTEATP 586
+++ S S + H +S+ SKEG + S E P Q + +P
Sbjct: 599 PNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSP 650
Score = 58.9 bits (141), Expect = 1e-08
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Query: 453 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTP------SVFNSDEERYRYREYAE 506
K RDR R R ++RD + ++ER+ R SP+ S +S E +R
Sbjct: 469 KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS 528
Query: 507 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 566
+ +R ++ +ER R + EE H+ SRS S+ R + + ++S+ S
Sbjct: 529 KERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSS 588
Query: 567 EGKEAGSEPAPEQESTEATP 586
E ++ +P ++S + P
Sbjct: 589 EERDHSRSRSPNKQSGYSRP 608
Score = 58.5 bits (140), Expect = 2e-08
Identities = 42/150 (28%), Positives = 65/150 (43%), Gaps = 6/150 (4%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRD----RERERTRERERERDHSPTPSVFNSD 495
D S+ Y R++ R R ++ R+ R R R+R R+R + RDHS + S N
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP-NKA 470
Query: 496 EERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR 555
+R R R ++ S KE HR R KE +S S+ R H S
Sbjct: 471 RDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKE 530
Query: 556 RHKHKKSKRSKEGKEAGS-EPAPEQESTEA 584
R + + +KE + S P+ E+E ++
Sbjct: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQS 560
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 15/160 (9%)
Query: 442 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRY 501
+KQ D+ R + ++ RDR R R + R+R R+R + RD S + S + + +
Sbjct: 396 NKQRDH--SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR 453
Query: 502 REYAERGYERHRASREKEERHR------ERRHRE----KEETRHKSSRSNSRRRHESEEG 551
R + R R+ + +R R ER H + +E H+ SRS S+ R +
Sbjct: 454 SPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSR 513
Query: 552 DSHRRHKHKKSKRSKEGKEAGSEPAPEQE---STEATPAE 588
S + H++S+ + ++ +P +E S +P+E
Sbjct: 514 SSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSE 553
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/137 (21%), Positives = 57/137 (41%), Gaps = 14/137 (10%)
Query: 450 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 509
R+ + ++ERDR + R +RE ++R +ERD R R+R +
Sbjct: 534 RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERD-------------RRRWRS-PSKER 579
Query: 510 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGK 569
ER ++ EER R +++ + R++S+ + S + H +S+ S +
Sbjct: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKES 639
Query: 570 EAGSEPAPEQESTEATP 586
+ P + +P
Sbjct: 640 DPSQSTVPRSPDWKRSP 656
Score = 43.9 bits (102), Expect = 4e-04
Identities = 79/362 (21%), Positives = 133/362 (36%), Gaps = 42/362 (11%)
Query: 228 NSEKETALPSTKAEFTSPPS----LFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDR 283
+S K T STK ++ PS + PSR ST ++ TS AS+ ++ + +
Sbjct: 60 SSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTR--TSKASKASDVRCHQRRGT 117
Query: 284 YGRAESPDLRRLPGAIDVIGQTITISRVEGR-RRANENSNIQVLSERSATEVDNNFSKPP 342
+ R +P R + + T R+ R S ++ + + ++ +P
Sbjct: 118 HSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPR 177
Query: 343 PFFPP--GAPPTHLPPPPFLPPPPT-VSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLI 399
+ P +L + PP + + + L P P G P + PS
Sbjct: 178 TSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPS-- 235
Query: 400 PTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRER 459
S S + YG + +P S+ +S+ Y + R +
Sbjct: 236 -----------PSSSRKVKSYGQMI---IPSREKSYSPTEMSSRVKSYNQASTRSRPQSH 281
Query: 460 DRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE 519
+ R R R ++RT R R N R R R+ RH SR
Sbjct: 282 SQSRSPRRSRSGSQKRTHSRVRSHSWKR-----NHSRARSRTRKGILSQMGRHSQSRS-- 334
Query: 520 ERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQ 579
H + + + + T + RS++ R+ S+E R H H +S SKE GS +P +
Sbjct: 335 --HSKGKSQNQSRTPRRG-RSHNWSRNPSKE----RSHSHSRSS-SKERDHRGSS-SPRK 385
Query: 580 ES 581
ES
Sbjct: 386 ES 387
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/169 (20%), Positives = 66/169 (39%), Gaps = 18/169 (10%)
Query: 430 GSAPSWPSLVDTSKQWDYYARREKDRD--------RERDRDRERDRDRDRERERTRERER 481
G + +W + + K+RD +E R + ++ R+ R+R +
Sbjct: 350 GRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK 409
Query: 482 ERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER---------RHREKEE 532
RD S + S + + + R R R+ + +R R R R R +
Sbjct: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK 469
Query: 533 TRHKS-SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 580
R +S SRS S+ R S+ G + H++S+ + ++ + +E
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
Score = 32.3 bits (72), Expect = 1.2
Identities = 21/112 (18%), Positives = 43/112 (38%)
Query: 475 RTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETR 534
R R R R + TPS ++D + + ++ + R + + R R + +
Sbjct: 77 RPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSP 136
Query: 535 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATP 586
++S R H + G + R ++ GK G +E +++ P
Sbjct: 137 SRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQP 188
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 66.6 bits (161), Expect = 6e-11
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 24/156 (15%)
Query: 451 REKDRDRERDR----------DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 500
REK+R+RER+ +RE++R RDRER R R R R R S T SD R
Sbjct: 257 REKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRT-----SDRRCSR 310
Query: 501 YREYAERGYERHRASREKEER------HRERRHREKEETRHKS-SRSNSRRRHESEEGDS 553
R++ R SR ++ R ER+HR + R +S SR +H S+ D
Sbjct: 311 SRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDR 370
Query: 554 HRRHKHK-KSKRSKEGKEAGSEPAPEQESTEATPAE 588
+ K K K KR + K++ + ++ +E T E
Sbjct: 371 EQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTE 406
Score = 63.9 bits (154), Expect = 4e-10
Identities = 47/132 (35%), Positives = 63/132 (47%), Gaps = 22/132 (16%)
Query: 453 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH 512
+ R E DRD +++ ER +ERERER+ + ER R RE ER ER
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKERERERE----------ERERKRRREEEEREKERA 284
Query: 513 RASREKEERHRER-RHREKEETR-------HKSSRSNSRRRHESEE---GDSHRRHKHKK 561
R RE+ +R R R RH + R HK SRS RRR S + SH R + K
Sbjct: 285 R-DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 562 SKRSKEGKEAGS 573
RS++ + + S
Sbjct: 344 RSRSRDRRRSKS 355
Score = 61.6 bits (148), Expect = 2e-09
Identities = 39/130 (30%), Positives = 59/130 (45%), Gaps = 15/130 (11%)
Query: 446 DYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYA 505
D ++EK ER+++RER+R+ ERER R RE E ++ER R RE
Sbjct: 244 DERLKKEKQEREEREKERERERE---ERERKRRREEEE----------REKERARDRERR 290
Query: 506 ERGYERHRASREKEERH--RERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563
+R R R S +R R R H+ + SRS RRR S + + + +
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
Query: 564 RSKEGKEAGS 573
R + ++ S
Sbjct: 351 RRSKSRDRKS 360
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 1/134 (0%)
Query: 442 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNS-DEERYR 500
S+ ++ R DR R RD +R R R+R R R+R+R R R H + S +R R
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR 352
Query: 501 YREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHK 560
+ + Y+ SR++E+ + + ++ KSS + R +SE+ ++ +
Sbjct: 353 SKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDT 412
Query: 561 KSKRSKEGKEAGSE 574
K++ + ++ SE
Sbjct: 413 KNEVNGTSEDIKSE 426
Score = 60.5 bits (145), Expect = 4e-09
Identities = 43/132 (32%), Positives = 56/132 (42%), Gaps = 27/132 (20%)
Query: 452 EKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYER 511
E+ +++ R R E DRD ++E+ ERE+ ER R RE ER R
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREK-------------EREREREERERKRRR 274
Query: 512 HRASREKEE-RHRERRHREKEETRHKS-------------SRSNSRRRHESEEGDSHRRH 557
REKE R RERR R + +RH S RS SR R S D R
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 558 KHKKSKRSKEGK 569
H +S+R +
Sbjct: 335 SHDRSERKHRSR 346
Score = 56.2 bits (134), Expect = 8e-08
Identities = 45/151 (29%), Positives = 67/151 (44%), Gaps = 26/151 (17%)
Query: 450 RREKDRDRERDRDRER---------------DRDRDRERERTRERERERDHSPTPSVFNS 494
R E++R++ER RDRER DR R R+ R R RER S +
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR-----SR 328
Query: 495 DEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKS-SRSNSRRRHESEE-GD 552
D R R + +ER +HR SR ++ R + R R+ + R KS R R+ E E+ G
Sbjct: 329 DRRRSRSHDRSER---KHR-SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS 384
Query: 553 SHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
++ K R K+ ++ +E E
Sbjct: 385 DDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
Score = 30.4 bits (67), Expect = 4.7
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 440 DTSKQWDYYARREKDRDRERDRD--RERDRDRDRERER-TRERERERDHSPTPSVFNSDE 496
D S++ R++ R + RDR + R + RDRE++R ++E+E+ SV +
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
Query: 497 ER 498
E+
Sbjct: 397 EK 398
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 66.6 bits (161), Expect = 6e-11
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 24/156 (15%)
Query: 451 REKDRDRERDR----------DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 500
REK+R+RER+ +RE++R RDRER R R R R R S T SD R
Sbjct: 257 REKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRT-----SDRRCSR 310
Query: 501 YREYAERGYERHRASREKEER------HRERRHREKEETRHKS-SRSNSRRRHESEEGDS 553
R++ R SR ++ R ER+HR + R +S SR +H S+ D
Sbjct: 311 SRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDR 370
Query: 554 HRRHKHK-KSKRSKEGKEAGSEPAPEQESTEATPAE 588
+ K K K KR + K++ + ++ +E T E
Sbjct: 371 EQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTE 406
Score = 63.9 bits (154), Expect = 4e-10
Identities = 47/132 (35%), Positives = 63/132 (47%), Gaps = 22/132 (16%)
Query: 453 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH 512
+ R E DRD +++ ER +ERERER+ + ER R RE ER ER
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKERERERE----------ERERKRRREEEEREKERA 284
Query: 513 RASREKEERHRER-RHREKEETR-------HKSSRSNSRRRHESEE---GDSHRRHKHKK 561
R RE+ +R R R RH + R HK SRS RRR S + SH R + K
Sbjct: 285 R-DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 562 SKRSKEGKEAGS 573
RS++ + + S
Sbjct: 344 RSRSRDRRRSKS 355
Score = 61.6 bits (148), Expect = 2e-09
Identities = 39/130 (30%), Positives = 59/130 (45%), Gaps = 15/130 (11%)
Query: 446 DYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYA 505
D ++EK ER+++RER+R+ ERER R RE E ++ER R RE
Sbjct: 244 DERLKKEKQEREEREKERERERE---ERERKRRREEEE----------REKERARDRERR 290
Query: 506 ERGYERHRASREKEERH--RERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 563
+R R R S +R R R H+ + SRS RRR S + + + +
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
Query: 564 RSKEGKEAGS 573
R + ++ S
Sbjct: 351 RRSKSRDRKS 360
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 1/134 (0%)
Query: 442 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNS-DEERYR 500
S+ ++ R DR R RD +R R R+R R R+R+R R R H + S +R R
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR 352
Query: 501 YREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHK 560
+ + Y+ SR++E+ + + ++ KSS + R +SE+ ++ +
Sbjct: 353 SKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDT 412
Query: 561 KSKRSKEGKEAGSE 574
K++ + ++ SE
Sbjct: 413 KNEVNGTSEDIKSE 426
Score = 60.5 bits (145), Expect = 4e-09
Identities = 43/132 (32%), Positives = 56/132 (42%), Gaps = 27/132 (20%)
Query: 452 EKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYER 511
E+ +++ R R E DRD ++E+ ERE+ ER R RE ER R
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREK-------------EREREREERERKRRR 274
Query: 512 HRASREKEE-RHRERRHREKEETRHKS-------------SRSNSRRRHESEEGDSHRRH 557
REKE R RERR R + +RH S RS SR R S D R
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 558 KHKKSKRSKEGK 569
H +S+R +
Sbjct: 335 SHDRSERKHRSR 346
Score = 56.2 bits (134), Expect = 8e-08
Identities = 45/151 (29%), Positives = 67/151 (44%), Gaps = 26/151 (17%)
Query: 450 RREKDRDRERDRDRER---------------DRDRDRERERTRERERERDHSPTPSVFNS 494
R E++R++ER RDRER DR R R+ R R RER S +
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR-----SR 328
Query: 495 DEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKS-SRSNSRRRHESEE-GD 552
D R R + +ER +HR SR ++ R + R R+ + R KS R R+ E E+ G
Sbjct: 329 DRRRSRSHDRSER---KHR-SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS 384
Query: 553 SHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 583
++ K R K+ ++ +E E
Sbjct: 385 DDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
Score = 30.4 bits (67), Expect = 4.7
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 440 DTSKQWDYYARREKDRDRERDRD--RERDRDRDRERER-TRERERERDHSPTPSVFNSDE 496
D S++ R++ R + RDR + R + RDRE++R ++E+E+ SV +
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
Query: 497 ER 498
E+
Sbjct: 397 EK 398
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 66.2 bits (160), Expect = 8e-11
Identities = 43/133 (32%), Positives = 68/133 (51%), Gaps = 11/133 (8%)
Query: 451 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 510
R DR+R+RDRDR+ +DR+R R+R+R R S + S S E R++E ER E
Sbjct: 24 RTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKE-RERDKE 82
Query: 511 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 570
R R K++R R++ +++ R +SS S R G + K + SK+ +E +
Sbjct: 83 R---DRNKKDRDRDKDGHRRDKDRKRSSLSPGR-------GKDFKSRKDRDSKKDEEDEH 132
Query: 571 AGSEPAPEQESTE 583
+P + S E
Sbjct: 133 GDKKPKAQPLSLE 145
Score = 64.3 bits (155), Expect = 3e-10
Identities = 45/143 (31%), Positives = 66/143 (46%), Gaps = 21/143 (14%)
Query: 452 EKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYER 511
+KDRD ++ +R R R RER+R+RD +PS D +R+R R+ RG R
Sbjct: 8 KKDRDASPSKE-----ERKRSRTPDRERDRDRDRKSSPS---KDRKRHRSRD-RRRGGSR 58
Query: 512 HRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKK--------SK 563
R+ + RERRH+E+E + + R R + D HRR K +K K
Sbjct: 59 SRSRSRSKSAERERRHKERERDKERDRNKKDRDR----DKDGHRRDKDRKRSSLSPGRGK 114
Query: 564 RSKEGKEAGSEPAPEQESTEATP 586
K K+ S+ E E + P
Sbjct: 115 DFKSRKDRDSKKDEEDEHGDKKP 137
Score = 52.4 bits (124), Expect = 1e-06
Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 13/144 (9%)
Query: 440 DTSKQWDYYARREKDRDRERDRDRERDR--DRDRERERTRERERERDHSPTPSVFNSDEE 497
D + D + +DR+R R R+R R R R R R++ ERER H D+E
Sbjct: 27 DRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKER----ERDKE 82
Query: 498 RYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 557
R R ++ +R + HR R ++R+ R K +S R + +E D H
Sbjct: 83 RDRNKKDRDRDKDGHR-------RDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDK 135
Query: 558 KHKKSKRSKEGKEAGSEPAPEQES 581
K K S E A + E E+
Sbjct: 136 KPKAQPLSLEELLAKKKAEEEAEA 159
Score = 43.1 bits (100), Expect = 7e-04
Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 35/155 (22%)
Query: 451 REKDRDRERDR---DRERDRD---RDRERERT-------------RERERERDHSPT--- 488
+E++RD+ERDR DR+RD+D RD++R+R+ ++R+ ++D
Sbjct: 75 KERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGD 134
Query: 489 --PSVFNSDEERYRYREYAERGYERHRASREKEERHRE---RRHREKEETRHKSSRSNSR 543
P E ++ AE E K ER E RR +E EE + +
Sbjct: 135 KKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKK 194
Query: 544 RRHESEEG--------DSHRRHKHKKSKRSKEGKE 570
R+ + G + RR + ++ +R G E
Sbjct: 195 RKQFQDLGRKMLEDPQERERRERRERMERETNGNE 229
Score = 32.3 bits (72), Expect = 1.2
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 16/101 (15%)
Query: 470 DRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHRE 529
+RE E + R++E + +EER + +++ + G + +E+E R ERR R
Sbjct: 168 EREAEALKRRQQEVEERQRML----EEERKKRKQFQDLGRKMLEDPQERERR--ERRERM 221
Query: 530 KEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 570
+ ET +E EEG R + KSK KE
Sbjct: 222 ERET----------NGNEDEEGRQKIREEKDKSKELHAIKE 252
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 65.5 bits (158), Expect = 1e-10
Identities = 59/191 (30%), Positives = 87/191 (45%), Gaps = 50/191 (26%)
Query: 342 PPFFPPGAPP---THLPP------PP-----FLPPPPTV----------STAPPLIPPPG 377
PP + PG+PP T PP PP F P PTV S P L PPP
Sbjct: 654 PPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPA 713
Query: 378 IPITVPP----------------PGFPPPPG---APPPSLIPT-IESGHSSGYDSRSARA 417
P + PP P P PP +PPP ++ + S+ ++ R
Sbjct: 714 APASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRG 773
Query: 418 F---PYGNVAFPHLPGS--APSWPSLVD-TSKQWDYYARREKDRDRERDRDRERDRDRDR 471
F ++ F L GS A LV+ ++ + AR EK+R+RER+R++ER+R+++R
Sbjct: 774 FNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKER 833
Query: 472 ERERTRERERE 482
E ER+ + +E
Sbjct: 834 ELERSVKLAQE 844
Score = 45.1 bits (105), Expect = 2e-04
Identities = 54/231 (23%), Positives = 80/231 (34%), Gaps = 77/231 (33%)
Query: 327 SERSATEVDNNFSKPPPFFPPGAPPTHLPPPPF---LPPPPTVSTAPP------------ 371
S + + V + P + +PP PPP+ P P TA P
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPG---PPPYGKRAPSPGAYKTATPPGYKPGSPPSFR 666
Query: 372 LIPPPGIPITVPP--------------------------PGFPPPPGAP---PPSLIPTI 402
PPG T PP P PPPP AP PP I
Sbjct: 667 TGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQI 726
Query: 403 ESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSL-----------VDTSKQWDYY--- 448
+ + Y++ + P + + P PS S ++ + D Y
Sbjct: 727 KQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVP 786
Query: 449 ----------------ARREKDRDRERDRDRERDRDRDRERERTRERERER 483
RRE ++ +++RER+R+R++ERER +ERE ER
Sbjct: 787 LEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELER 837
Score = 42.7 bits (99), Expect = 0.001
Identities = 44/146 (30%), Positives = 54/146 (36%), Gaps = 37/146 (25%)
Query: 339 SKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPP--------GFPPP 390
S PPP P P +LPPPP L P S +PP + +P +P P G PP
Sbjct: 287 SAPPPANFPHVTP-NLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345
Query: 391 PG-----APPPSLIPTIES---------------------GHSSGYDSRSARAFPYGNVA 424
P AP P +P S SS S SA FP + A
Sbjct: 346 PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP-ASQA 404
Query: 425 FPHLPGSAPSWPSLVDTSKQWDYYAR 450
P P S P P+ + S Q Y +
Sbjct: 405 LPSYPHSFPP-PTSLSVSNQPPKYTQ 429
Score = 40.4 bits (93), Expect = 0.005
Identities = 50/195 (25%), Positives = 73/195 (37%), Gaps = 25/195 (12%)
Query: 227 GNSEKET-ALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANS--------SV 277
G +EK + E S P + K G S + S+S+ + A +K + S
Sbjct: 45 GKAEKSRQTAKKARVEEASTPKVNKQGR--SEEISESESEETNAPKKTKTEQELPRPQSP 102
Query: 278 GKWQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNN 337
GR+ + D P ID ++ + S N++ + LS+ A
Sbjct: 103 SDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARP---- 158
Query: 338 FSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPG---FPPPPGAP 394
+ PP F P PP P P P P + P G + PP F PPGAP
Sbjct: 159 YHPPPLFPPSPQPPDSTPRQPEASFEP-----HPSVTPTGYHAPMEPPTSRMFQAPPGAP 213
Query: 395 PPSLIPTIESGHSSG 409
PP P + G + G
Sbjct: 214 PPH--PQLYPGGTGG 226
Score = 32.7 bits (73), Expect = 0.96
Identities = 45/132 (34%), Positives = 51/132 (38%), Gaps = 41/132 (31%)
Query: 341 PPPFFP--------PGAPPTHLPPPPF----LP--PPPT--VSTAPPLIPPPGI-PI--- 380
PPP P GAPPT P P LP PPP P L PPP + P+
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA 313
Query: 381 --------TVPPPGFPPPP--------GAPP-PSLIPTI-ESGHSSGYDSRSARAFPYGN 422
P PG P P G PP P PT+ S HS S SA A P
Sbjct: 314 SASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP--- 370
Query: 423 VAFPHLPGSAPS 434
+ FP+ S+ S
Sbjct: 371 MRFPYSSSSSSS 382
Score = 30.0 bits (66), Expect = 6.2
Identities = 23/69 (33%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 327 SERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPT---VSTAPPLIPPPGIPI-TV 382
S S+ ++ S P LP P PPPT VS PP P +P V
Sbjct: 378 SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAV 437
Query: 383 PPPGFPPPP 391
G PPPP
Sbjct: 438 WSQGPPPPP 446
Score = 30.0 bits (66), Expect = 6.2
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 14/75 (18%)
Query: 345 FPPGAPPTHLPPP----------PFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAP 394
+PPG P HLPPP P PP + S + P + P P P GAP
Sbjct: 542 YPPG--PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS-QGPQGAP 598
Query: 395 PP-SLIPTIESGHSS 408
P +PT+ + ++
Sbjct: 599 YPFPPVPTVTTSSAT 613
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.129 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,226,027
Number of Sequences: 37866
Number of extensions: 2145642
Number of successful extensions: 60834
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1049
Number of HSP's successfully gapped in prelim test: 1293
Number of HSP's that attempted gapping in prelim test: 17125
Number of HSP's gapped (non-prelim): 19692
length of query: 588
length of database: 18,247,518
effective HSP length: 108
effective length of query: 480
effective length of database: 14,157,990
effective search space: 6795835200
effective search space used: 6795835200
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.