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Search of human proteins with 196162711
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
(246 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens] 506 e-144
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 467 e-132
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 149 3e-36
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 143 2e-34
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens] 135 4e-32
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens] 114 6e-26
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens] 114 6e-26
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens] 113 2e-25
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 107 7e-24
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 107 7e-24
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 100 9e-22
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 100 9e-22
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens] 98 8e-21
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 98 8e-21
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 97 2e-20
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 96 2e-20
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 92 3e-19
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 92 5e-19
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 91 7e-19
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 65 4e-11
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 60 1e-09
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 60 1e-09
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 60 1e-09
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 54 2e-07
gi|118600967 shroom family member 4 [Homo sapiens] 49 4e-06
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 48 9e-06
gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens] 48 9e-06
gi|203098098 shroom family member 3 protein [Homo sapiens] 47 2e-05
gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens] 47 2e-05
gi|194018553 solute carrier family 9 isoform 3 regulator 2 isofo... 45 8e-05
>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
Length = 246
Score = 506 bits (1304), Expect = e-144
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
Sbjct: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
Sbjct: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
Query: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR 180
GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
Sbjct: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR 180
Query: 181 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTIPSAS 240
DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTIPSAS
Sbjct: 181 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTIPSAS 240
Query: 241 CAVTAA 246
CAVTAA
Sbjct: 241 CAVTAA 246
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 467 bits (1201), Expect = e-132
Identities = 228/240 (95%), Positives = 230/240 (95%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM
Sbjct: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS
Sbjct: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
Query: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR 180
GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR
Sbjct: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSR 180
Query: 181 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTIPSAS 240
DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGG G + P+AS
Sbjct: 181 DCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTAS 240
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 149 bits (375), Expect = 3e-36
Identities = 98/241 (40%), Positives = 129/241 (53%), Gaps = 18/241 (7%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
+ L+GP PWGFRLVGG+DF PL ISRV GSKAALA LC GD+I AI+GE+T MTHLE
Sbjct: 6 IDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLE 65
Query: 65 AQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQD-----GSPTTSRR 118
AQNRIKGC D+LTL+V+R E + W P ++ K +++++ E Q+ + S
Sbjct: 66 AQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAM 125
Query: 119 PSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSS-----EATLPAQMSTLHVSPPPSADPA 173
P + + Y P N S+ E+ A + P A P
Sbjct: 126 PFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPP 185
Query: 174 RGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTS 233
L +D SEVY+ML+E E + PKQS SF LQ +LE+ E G P+ G
Sbjct: 186 SSLV------IDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNKPSGFR 238
Query: 234 S 234
S
Sbjct: 239 S 239
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
Length = 316
Score = 143 bits (360), Expect = 2e-34
Identities = 90/243 (37%), Positives = 126/243 (51%), Gaps = 20/243 (8%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
MP +V L GP+PWGFRL GG DF+ PL I+R+ GSKAA A LCPGD+I AI+G TE M
Sbjct: 1 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSP-----T 114
TH +AQ+RIK L L + R E W P +D KA +I+++ E Q+ P
Sbjct: 61 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN 120
Query: 115 TSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPAR 174
+P +D R + + Y P + + + L Q+ L + P +P
Sbjct: 121 RRAQPFVAAANIDDKRQVVSASYNSP--IGLYSTSNIQDALHGQLRGL-IPSSPQNEPTA 177
Query: 175 GLPRSRDCRVDLGSEVYRMLREPA-EPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTS 233
+P S+VYRML + EP +P+QSGSFR LQGM++ G P+
Sbjct: 178 SVPPE--------SDVYRMLHDNRNEP--TQPRQSGSFRVLQGMVDDGSDDRPAGTRSVR 227
Query: 234 STI 236
+ +
Sbjct: 228 APV 230
>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]
Length = 364
Score = 135 bits (339), Expect = 4e-32
Identities = 97/288 (33%), Positives = 130/288 (45%), Gaps = 62/288 (21%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
MP +V L GP+PWGFRL GG DF+ PL I+R+ GSKAA A LCPGD+I AI+G TE M
Sbjct: 1 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGS------- 112
TH +AQ+RIK L L + R E W P +D KA +I+++ E QDG+
Sbjct: 61 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
Query: 113 -----------PTTSRRPSGTGTGPEDGRPSLGSPYGQ------------PPRFPVP--- 146
+ PSG G PS S P P+
Sbjct: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180
Query: 147 -----------------HNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSE 189
+ + TL Q+ST P ++P +P S+
Sbjct: 181 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPE--------SD 232
Query: 190 VYRMLREPA-EPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTI 236
VYRML + EP +P+QSGSFR LQGM++ G P+ + +
Sbjct: 233 VYRMLHDNRNEP--TQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPV 278
>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
Length = 366
Score = 114 bits (286), Expect = 6e-26
Identities = 93/285 (32%), Positives = 128/285 (44%), Gaps = 47/285 (16%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
M +V + GP+PWGFR+ GGRDF P+ +++V KA A L PGD+I AINGES E M
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
H EAQ++I+ L L + R + S DS + ++ + + S S
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
Query: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSP-------------- 166
+ P P GSP+ PP + + EA + +L SP
Sbjct: 121 SYSS-PTSLSPRAGSPFSPPPS---SSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRP 176
Query: 167 ------------------PPSADPARGLPRSRDCR-----VDLGSEVYRMLREPAEPVAA 203
PPS P P S D +D SEV++ML+E E AA
Sbjct: 177 GSRQAGLGRAGDSAVLVLPPSPGPRSSRP-SMDSEGGSLLLDEDSEVFKMLQENREGRAA 235
Query: 204 EPKQSGSFRYLQGMLEAGE-GGAPS---SRHGTSSTIPSASCAVT 244
P+QS SFR LQ LEA E GG P+ S S++P++ T
Sbjct: 236 -PRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALAT 279
>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
Length = 352
Score = 114 bits (286), Expect = 6e-26
Identities = 93/285 (32%), Positives = 128/285 (44%), Gaps = 47/285 (16%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
M +V + GP+PWGFR+ GGRDF P+ +++V KA A L PGD+I AINGES E M
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
H EAQ++I+ L L + R + S DS + ++ + + S S
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
Query: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSP-------------- 166
+ P P GSP+ PP + + EA + +L SP
Sbjct: 121 SYSS-PTSLSPRAGSPFSPPPS---SSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRP 176
Query: 167 ------------------PPSADPARGLPRSRDCR-----VDLGSEVYRMLREPAEPVAA 203
PPS P P S D +D SEV++ML+E E AA
Sbjct: 177 GSRQAGLGRAGDSAVLVLPPSPGPRSSRP-SMDSEGGSLLLDEDSEVFKMLQENREGRAA 235
Query: 204 EPKQSGSFRYLQGMLEAGE-GGAPS---SRHGTSSTIPSASCAVT 244
P+QS SFR LQ LEA E GG P+ S S++P++ T
Sbjct: 236 -PRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALAT 279
>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
Length = 278
Score = 113 bits (282), Expect = 2e-25
Identities = 91/274 (33%), Positives = 123/274 (44%), Gaps = 46/274 (16%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
M +V + GP+PWGFR+ GGRDF P+ +++V KA A L PGD+I AINGES E M
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
H EAQ++I+ L L + R + S DS + ++ + + S S
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
Query: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSP-------------- 166
+ P P GSP+ PP + + EA + +L SP
Sbjct: 121 SYSS-PTSLSPRAGSPFSPPPS---SSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRP 176
Query: 167 ------------------PPSADPARGLPRSRDCR-----VDLGSEVYRMLREPAEPVAA 203
PPS P P S D +D SEV++ML+E E AA
Sbjct: 177 GSRQAGLGRAGDSAVLVLPPSPGPRSSRP-SMDSEGGSLLLDEDSEVFKMLQENREGRAA 235
Query: 204 EPKQSGSFRYLQGMLEAGEGG---APSSRHGTSS 234
P+QS SFR LQ LEA E G S R GT++
Sbjct: 236 -PRQSSSFRLLQEALEAEERGTRLCASRRAGTAT 268
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 107 bits (268), Expect = 7e-24
Identities = 79/214 (36%), Positives = 106/214 (49%), Gaps = 17/214 (7%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
M +SVTL GP PWGFRL GG+DF+ PLTISR+ GSKAA + L GDL+ AI+G +T+ M
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNRIKGCHDHLTLSV---SRPEGRSWPSAPDDSKAQAHRIHIDPEIQDG------ 111
THLEAQN+IK +L+L++ RP S + P + DP +
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
Query: 112 SPTTSRRPSGTGTGPEDGRPSLGSPYGQPPRF----PVPHNGSSEATLPAQMSTLHVSP- 166
SP+ R S G + RP+ + +P F G A+L A+ S
Sbjct: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
Query: 167 -PPSADPARGLPRSRDCRVDLGSEVYRMLREPAE 199
P A P PR + + L S LRE A+
Sbjct: 181 LGPKALPGSSQPRQYNNPIGLYSA--ETLREMAQ 212
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 107 bits (268), Expect = 7e-24
Identities = 79/214 (36%), Positives = 106/214 (49%), Gaps = 17/214 (7%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
M +SVTL GP PWGFRL GG+DF+ PLTISR+ GSKAA + L GDL+ AI+G +T+ M
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNRIKGCHDHLTLSV---SRPEGRSWPSAPDDSKAQAHRIHIDPEIQDG------ 111
THLEAQN+IK +L+L++ RP S + P + DP +
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
Query: 112 SPTTSRRPSGTGTGPEDGRPSLGSPYGQPPRF----PVPHNGSSEATLPAQMSTLHVSP- 166
SP+ R S G + RP+ + +P F G A+L A+ S
Sbjct: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
Query: 167 -PPSADPARGLPRSRDCRVDLGSEVYRMLREPAE 199
P A P PR + + L S LRE A+
Sbjct: 181 LGPKALPGSSQPRQYNNPIGLYSA--ETLREMAQ 212
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 100 bits (250), Expect = 9e-22
Identities = 48/82 (58%), Positives = 63/82 (76%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
M +SVTL GP PWGFRL GG+DF+ PLTISR+ GSKAA + L GDL+ AI+G +T+ M
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSR 82
THLEAQN+IK +L+L++ +
Sbjct: 61 THLEAQNKIKSASYNLSLTLQK 82
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 100 bits (250), Expect = 9e-22
Identities = 48/82 (58%), Positives = 63/82 (76%)
Query: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
M +SVTL GP PWGFRL GG+DF+ PLTISR+ GSKAA + L GDL+ AI+G +T+ M
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNRIKGCHDHLTLSVSR 82
THLEAQN+IK +L+L++ +
Sbjct: 61 THLEAQNKIKSASYNLSLTLQK 82
>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
Length = 222
Score = 97.8 bits (242), Expect = 8e-21
Identities = 58/143 (40%), Positives = 79/143 (55%), Gaps = 8/143 (5%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
V L GP+PWGFRL GG+DF+ PL+ISR+ G KAA A + GD + +I+GE+ +TH+E
Sbjct: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
Query: 65 AQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQ-AHRIHIDPEIQDGSPTTSRRPSGTG 123
AQN+I+ C + L+L +SR + P SK Q A DP +P+ S +
Sbjct: 66 AQNKIRACGERLSLGLSRAQ-------PVQSKPQKASAPAADPPRYTFAPSVSLNKTARP 118
Query: 124 TGPEDGRPSLGSPYGQPPRFPVP 146
G S GQP R VP
Sbjct: 119 FGAPPPADSAPQQNGQPLRPLVP 141
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 97.8 bits (242), Expect = 8e-21
Identities = 58/143 (40%), Positives = 79/143 (55%), Gaps = 8/143 (5%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
V L GP+PWGFRL GG+DF+ PL+ISR+ G KAA A + GD + +I+GE+ +TH+E
Sbjct: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
Query: 65 AQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQ-AHRIHIDPEIQDGSPTTSRRPSGTG 123
AQN+I+ C + L+L +SR + P SK Q A DP +P+ S +
Sbjct: 66 AQNKIRACGERLSLGLSRAQ-------PVQSKPQKASAPAADPPRYTFAPSVSLNKTARP 118
Query: 124 TGPEDGRPSLGSPYGQPPRFPVP 146
G S GQP R VP
Sbjct: 119 FGAPPPADSAPQQNGQPLRPLVP 141
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 96.7 bits (239), Expect = 2e-20
Identities = 64/169 (37%), Positives = 88/169 (52%), Gaps = 6/169 (3%)
Query: 3 HSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTH 62
+SV+L GP+PWGFRL GG+DF+ PLTIS + G KAA A + GD++ +I+G + + MTH
Sbjct: 4 YSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTH 63
Query: 63 LEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPSGT 122
LEAQN+IKGC L +++ R P K + + + P + SP S+ S
Sbjct: 64 LEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEV-VKP-VPITSPAVSKVTSTN 121
Query: 123 GTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMST-LHVSPPPSA 170
GS P +P S A PA +T H SP P A
Sbjct: 122 NMAYNKAPRPFGS-VSSPKVTSIP--SPSSAFTPAHATTSSHASPSPVA 167
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 96.3 bits (238), Expect = 2e-20
Identities = 81/262 (30%), Positives = 116/262 (44%), Gaps = 41/262 (15%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
V L GP+PWGFRL GG+DF+ PL+ISR+ G KAA A + GD + +I+GE+ +TH+E
Sbjct: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
Query: 65 AQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQA-HRIHIDPEIQDGSP------TTSR 117
AQN+I+ C + L+L +SR + P K Q + + P + D S T
Sbjct: 66 AQNKIRACGERLSLGLSRAQ----PVQSKPQKVQTPDKQPLRPLVPDASKQRLMENTEDW 121
Query: 118 RP-SGTG-----------TGPE---DGRPSLGSPYGQPPR--FPVPHNGSSEATLPAQMS 160
RP GTG TG E D Q PR P P + + + P +
Sbjct: 122 RPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTA 181
Query: 161 TLHVSPPP-SADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLE 219
S PP + DPA + D + +L ++P P QS + +++
Sbjct: 182 PSPTSRPPWAVDPAFAERYAPD-------KTSTVLTRHSQPATPTPLQSRT-----SIVQ 229
Query: 220 AGEGGAPSSRHGTSSTIPSASC 241
A GG P T C
Sbjct: 230 AAAGGVPGGGSNNGKTPVCHQC 251
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 92.4 bits (228), Expect = 3e-19
Identities = 51/126 (40%), Positives = 72/126 (57%), Gaps = 2/126 (1%)
Query: 3 HSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTH 62
+SV+L GP+PWGFRL GG+DF+ PLTIS + G KAA A + GD++ +I+G + + MTH
Sbjct: 4 YSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTH 63
Query: 63 LEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRI--HIDPEIQDGSPTTSRRPS 120
LEAQN+IKGC L +++ R P K + E+ +G S+ S
Sbjct: 64 LEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQGDS 123
Query: 121 GTGTGP 126
GP
Sbjct: 124 KQQNGP 129
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 91.7 bits (226), Expect = 5e-19
Identities = 47/97 (48%), Positives = 64/97 (65%), Gaps = 1/97 (1%)
Query: 3 HSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTH 62
+SV+L GP+PWGFRL GG+DF+ PLTIS + G KAA A + GD++ +I+G + + MTH
Sbjct: 4 YSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTH 63
Query: 63 LEAQNRIKGCHDHLTLSVSRPEGRSWPS-APDDSKAQ 98
LEAQN+IKGC L +++ R P P K Q
Sbjct: 64 LEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKKTQ 100
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 91.3 bits (225), Expect = 7e-19
Identities = 55/142 (38%), Positives = 80/142 (56%), Gaps = 10/142 (7%)
Query: 3 HSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTH 62
+SV+L GP+PWGFRL GG+DF+ PLTIS + G KAA A + GD++ +I+G + + MTH
Sbjct: 4 YSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTH 63
Query: 63 LEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRI--HIDPEIQDGSPTTSRRPS 120
LEAQN+IKGC L +++ R P K + E+ +G RR S
Sbjct: 64 LEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKPTVTSVCSETSQELAEG----QRRGS 119
Query: 121 GTGTGPEDGRPSLGSPYGQPPR 142
+ ++G+ P +PPR
Sbjct: 120 QGDSKQQNGK----IPPKRPPR 137
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 65.5 bits (158), Expect = 4e-11
Identities = 56/184 (30%), Positives = 82/184 (44%), Gaps = 14/184 (7%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
VTL G +PWGFRL GG + PL +S++ S+A A L D + AING S ++H
Sbjct: 9 VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHAS 68
Query: 65 AQNRIKGCHDHLTLSVSR--PEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPSGT 122
A + I + L L+V R EG +P + + + + PE G+P G+
Sbjct: 69 AMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPE-PPGAPVPQPLQPGS 127
Query: 123 GTGPEDGRPSLGSPYG--------QPPRFPVPHNGSSEATLP-AQMSTLHVSPPPSADPA 173
P D G + PR P G + T P A +++S P A+PA
Sbjct: 128 LRSPPDSEAYYGETDSDADGPATQEKPRRP-RRRGPTRPTPPGAPPDEVYLSDSP-AEPA 185
Query: 174 RGLP 177
+P
Sbjct: 186 PTIP 189
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 60.5 bits (145), Expect = 1e-09
Identities = 27/79 (34%), Positives = 47/79 (59%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
+++ G +PWGFRL GG++ PL ++++ SKA+ + LC GD + +ING +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 65 AQNRIKGCHDHLTLSVSRP 83
++ D L + + RP
Sbjct: 69 VIKLMESITDSLQMLIKRP 87
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 60.5 bits (145), Expect = 1e-09
Identities = 27/79 (34%), Positives = 47/79 (59%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
+++ G +PWGFRL GG++ PL ++++ SKA+ + LC GD + +ING +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 65 AQNRIKGCHDHLTLSVSRP 83
++ D L + + RP
Sbjct: 69 VIKLMESITDSLQMLIKRP 87
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 60.5 bits (145), Expect = 1e-09
Identities = 27/79 (34%), Positives = 47/79 (59%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
+++ G +PWGFRL GG++ PL ++++ SKA+ + LC GD + +ING +T+ E
Sbjct: 9 ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68
Query: 65 AQNRIKGCHDHLTLSVSRP 83
++ D L + + RP
Sbjct: 69 VIKLMESITDSLQMLIKRP 87
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 53.5 bits (127), Expect = 2e-07
Identities = 35/85 (41%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSK-AALAALCPGDLIQAINGESTELMTHL 63
V L G +PWGF L GGR+ PL I+++ GSK AA+ L GD I IN
Sbjct: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
Query: 64 EAQNRIKGCHDHLTLSVSRPEGRSW 88
EA +KG H L L V R W
Sbjct: 88 EAICLVKGSHKTLKLVVKRRSELGW 112
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 48.9 bits (115), Expect = 4e-06
Identities = 35/80 (43%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Query: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALA-ALCPGDLIQAINGESTELM-TH 62
V L+G +PWGF L GG + PLT+S++ G KAAL+ + GD + ING T L +
Sbjct: 13 VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNING--TPLYGSR 70
Query: 63 LEAQNRIKGCHDHLTLSVSR 82
EA IKG L L V R
Sbjct: 71 QEALILIKGSFRILKLIVRR 90
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 47.8 bits (112), Expect = 9e-06
Identities = 52/176 (29%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 8 RGPSPWGFRLVGGRDFSAPLTISRV-HAGSKAALAALCPGDLIQAINGESTELMTHLEAQ 66
RG +GF L GGR+++ L + R+ G + GD I INGE+T+ M H A
Sbjct: 1128 RGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAI 1187
Query: 67 NRIKGCHDHLTLSVSRPEGRSWPSAP-DDSKAQAHRIHIDPEIQDGSPTTSRRPSGTGTG 125
IK + L + R +G P D A PE++ G P + PS +
Sbjct: 1188 ELIKNGGRRVRLFLKRGDGSVPEYDPSSDRHGPATGPQGVPEVRAG-PDRRQHPSLESSY 1246
Query: 126 PEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRD 181
P D S SP+G+ GS E + Q + H S P G R +D
Sbjct: 1247 PPDLHKS--SPHGEKRAHARDPKGSREYS--RQPNEHHTWNGTSRKPDSGACRPKD 1298
Score = 28.1 bits (61), Expect = 7.3
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 29/144 (20%)
Query: 8 RGPSPWGFRLVGGRDFSAPLTISR-VHAGSKAALAALCPGDLIQAIN-----GESTELMT 61
R + +GFR++GG + P+ I V G+ L GD + ++ G+S +L+
Sbjct: 818 RKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVV 877
Query: 62 HLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDD--SKAQAHRIHIDP------------- 106
L Q +G H+ L+V R + P ++ S A +H P
Sbjct: 878 QLMQQAAKQG---HVNLTVRRKVVFAVPKTENEVPSPASSHHSSNQPASLTEEKRTPQGS 934
Query: 107 -----EIQDGSPTTSRRPSGTGTG 125
+ GS +TS SG G G
Sbjct: 935 QNSLNTVSSGSGSTSGIGSGGGGG 958
>gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]
Length = 262
Score = 47.8 bits (112), Expect = 9e-06
Identities = 52/178 (29%), Positives = 72/178 (40%), Gaps = 17/178 (9%)
Query: 7 LRGPSPWGFRLVGGRDFSA--PLTI-SRVHAGSKAALAALCPGDLIQAINGESTELMTHL 63
+RG + +G L GGRD + PL + + G L GDL+ INGEST+ +TH
Sbjct: 62 VRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTHA 121
Query: 64 EAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPSGTG 123
+A RI+ L L + RP + P P + P+ T SR S +
Sbjct: 122 QAVERIRAGGPQLHLVIRRPL-ETHPGKPRGVGEPRKGVDRSPDPGGPEVTGSRSSSTSL 180
Query: 124 TGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPP--SADPARGLPRS 179
R +L G P P P + T VSPP + DP +P S
Sbjct: 181 VQHPPSRTTLKKTRGSPE--PSPEAAADGPT---------VSPPERRAEDPNDQIPGS 227
>gi|203098098 shroom family member 3 protein [Homo sapiens]
Length = 1996
Score = 47.0 bits (110), Expect = 2e-05
Identities = 32/78 (41%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 7 LRGPSPWGFRLVGGRDFSAPLTISRVHAGSKA--ALAALCPGDLIQAINGESTELMTHLE 64
L G +PWGF L GG + PL IS+V G KA + L GD + IN E T + E
Sbjct: 32 LEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHIN-EVTLSSSRKE 90
Query: 65 AQNRIKGCHDHLTLSVSR 82
A + +KG + L L V R
Sbjct: 91 AVSLVKGSYKTLRLVVRR 108
>gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]
Length = 334
Score = 46.6 bits (109), Expect = 2e-05
Identities = 57/180 (31%), Positives = 75/180 (41%), Gaps = 16/180 (8%)
Query: 7 LRGPSPWGFRLVGGRDFSA--PLTI-SRVHAGSKAALAALCPGDLIQAINGESTELMTHL 63
+RG + +G L GGRD + PL + + G L GDL+ INGEST+ +TH
Sbjct: 129 VRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTHA 188
Query: 64 EAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPSGTG 123
+A RI+ L L + RP + P P R + P D SP P TG
Sbjct: 189 QAVERIRAGGPQLHLVIRRPL-ETHPGKP--RGVGEPRKGVVPSWPDRSPDPG-GPEVTG 244
Query: 124 TGPEDGRPSLGSPYGQPPRFPV--PHNGSSEATLPAQMSTLHVSPPP--SADPARGLPRS 179
+ R S S PP GS E + A VSPP + DP +P S
Sbjct: 245 S-----RSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGS 299
>gi|194018553 solute carrier family 9 isoform 3 regulator 2 isoform
a [Homo sapiens]
Length = 337
Score = 44.7 bits (104), Expect = 8e-05
Identities = 48/160 (30%), Positives = 65/160 (40%), Gaps = 12/160 (7%)
Query: 8 RGPSPWGFRLVGGRDFSAP-LTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQ 66
+GP +GF L D S P I V GS AA + L D + +NG++ E + H E
Sbjct: 156 KGPQGYGFNLHS--DKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVV 213
Query: 67 NRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPSGTGTGP 126
IK D L V PE D + R+ E +G P S +GT
Sbjct: 214 ASIKAREDEARLLVVDPE--------TDEHFKRLRVTPTEEHVEG-PLPSPVTNGTSPAQ 264
Query: 127 EDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSP 166
+G + S P +GS+ P Q S LH+SP
Sbjct: 265 LNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSP 304
Score = 39.3 bits (90), Expect = 0.003
Identities = 27/74 (36%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 7 LRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLEAQ 66
+RG +GF L G + I RV GS A AAL GD + +NG + E TH +
Sbjct: 15 VRGEQGYGFHLHGEKGRRGQF-IRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVV 73
Query: 67 NRIKGCHDHLTLSV 80
RIK L V
Sbjct: 74 QRIKAVEGQTRLLV 87
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,396,109
Number of Sequences: 37866
Number of extensions: 767242
Number of successful extensions: 3490
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 341
Number of HSP's that attempted gapping in prelim test: 2996
Number of HSP's gapped (non-prelim): 825
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.