Guide to the Human Genome
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Search of human proteins with 194306631

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo
sapiens]
         (371 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]      736   0.0  
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]      664   0.0  
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]      503   e-143
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]      498   e-141
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]      498   e-141
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]       487   e-138
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]      485   e-137
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]       481   e-136
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]      479   e-135
gi|222352151 poly(rC) binding protein 1 [Homo sapiens]                423   e-118
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]       379   e-105
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]       379   e-105
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]        293   2e-79
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ...   106   4e-23
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ...   106   4e-23
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ...   106   4e-23
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]          94   3e-19
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo...    88   1e-17
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ...    86   4e-17
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ...    85   9e-17
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ...    85   9e-17
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        85   9e-17
gi|17402900 far upstream element-binding protein [Homo sapiens]        82   8e-16
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ...    77   2e-14
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ...    76   4e-14
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ...    74   2e-13
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1...    72   6e-13
gi|145312259 tudor and KH domain containing isoform a [Homo sapi...    58   2e-08
gi|145312270 tudor and KH domain containing isoform a [Homo sapi...    58   2e-08
gi|145312256 tudor and KH domain containing isoform a [Homo sapi...    58   2e-08

>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
          Length = 371

 Score =  736 bits (1901), Expect = 0.0
 Identities = 371/371 (100%), Positives = 371/371 (100%)

Query: 1   MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI 60
           MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI
Sbjct: 1   MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI 60

Query: 61  IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS 120
           IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS
Sbjct: 61  IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS 120

Query: 121 NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
           NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI
Sbjct: 121 NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180

Query: 181 SGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQ 240
           SGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQ
Sbjct: 181 SGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQ 240

Query: 241 LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI 300
           LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI
Sbjct: 241 LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI 300

Query: 301 PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR 360
           PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR
Sbjct: 301 PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR 360

Query: 361 LTSEVTGMGTL 371
           LTSEVTGMGTL
Sbjct: 361 LTSEVTGMGTL 371


>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
          Length = 345

 Score =  664 bits (1713), Expect = 0.0
 Identities = 345/371 (92%), Positives = 345/371 (92%), Gaps = 26/371 (7%)

Query: 1   MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI 60
           MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI
Sbjct: 1   MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSI 60

Query: 61  IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS 120
           IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS
Sbjct: 61  IGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMS 120

Query: 121 NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
           NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI
Sbjct: 121 NSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180

Query: 181 SGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQ 240
           SGTPDAIIQCVKQICVVMLE                         AYTIQGQYAIPHPD 
Sbjct: 181 SGTPDAIIQCVKQICVVMLE-------------------------AYTIQGQYAIPHPD- 214

Query: 241 LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI 300
           LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI
Sbjct: 215 LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTI 274

Query: 301 PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR 360
           PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR
Sbjct: 275 PNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINAR 334

Query: 361 LTSEVTGMGTL 371
           LTSEVTGMGTL
Sbjct: 335 LTSEVTGMGTL 345


>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
          Length = 331

 Score =  503 bits (1296), Expect = e-143
 Identities = 263/338 (77%), Positives = 293/338 (86%), Gaps = 8/338 (2%)

Query: 33  MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
           M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1   MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60

Query: 93  ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
           + GPT+AIFKAFAMI  K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61  LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120

Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRP 212
           KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLESPPKG TIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180

Query: 213 KPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLH 272
           KP+S+PVIFAGGQAYTIQGQYAIP PD LTKLHQLAMQQ+ F P+   N  F G    + 
Sbjct: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPD-LTKLHQLAMQQSHF-PMTHGNTGFSG----IE 234

Query: 273 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANA 332
           SS  +  + G  +GLDAS   ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN 
Sbjct: 235 SS--SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP 292

Query: 333 TEGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 370
            EGS++RQ+TITG+ A+ISLAQYLIN RL+SE  GMG+
Sbjct: 293 VEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 330


>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
          Length = 318

 Score =  498 bits (1281), Expect = e-141
 Identities = 261/339 (76%), Positives = 287/339 (84%), Gaps = 23/339 (6%)

Query: 33  MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
           M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1   MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60

Query: 93  ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
           + GPT+AIFKAFAMI  K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61  LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120

Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRP 212
           KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLESPPKG TIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180

Query: 213 KPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPL-GQTNPAFPGEKLPL 271
           KP+S+PVIFAGGQAYTIQGQYAIP PD LTKLHQLAMQQ+ FP   G T           
Sbjct: 181 KPSSSPVIFAGGQAYTIQGQYAIPQPD-LTKLHQLAMQQSHFPMTHGNT----------- 228

Query: 272 HSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIAN 331
                     G S+GLDAS   ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN
Sbjct: 229 ----------GFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 278

Query: 332 ATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 370
             EGS++RQ+TITG+ A+ISLAQYLIN RL+SE  GMG+
Sbjct: 279 PVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 317


>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
          Length = 335

 Score =  498 bits (1281), Expect = e-141
 Identities = 263/342 (76%), Positives = 293/342 (85%), Gaps = 12/342 (3%)

Query: 33  MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
           M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1   MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60

Query: 93  ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
           + GPT+AIFKAFAMI  K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61  LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120

Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE----SPPKGATI 208
           KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE    SPPKG TI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180

Query: 209 PYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEK 268
           PYRPKP+S+PVIFAGGQAYTIQGQYAIP PD LTKLHQLAMQQ+ F P+   N  F G  
Sbjct: 181 PYRPKPSSSPVIFAGGQAYTIQGQYAIPQPD-LTKLHQLAMQQSHF-PMTHGNTGFSG-- 236

Query: 269 LPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIK 328
             + SS  +  + G  +GLDAS   ++HELTIPNDLIGCIIGRQG KINEIRQMSGAQIK
Sbjct: 237 --IESS--SPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIK 292

Query: 329 IANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGT 370
           IAN  EGS++RQ+TITG+ A+ISLAQYLIN RL+SE  GMG+
Sbjct: 293 IANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGS 334


>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
          Length = 362

 Score =  487 bits (1254), Expect = e-138
 Identities = 263/369 (71%), Positives = 293/369 (79%), Gaps = 39/369 (10%)

Query: 33  MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
           M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1   MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60

Query: 93  ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
           + GPT+AIFKAFAMI  K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61  LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120

Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRP 212
           KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLESPPKG TIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180

Query: 213 KPASTPVIFAGGQ-------------------------------AYTIQGQYAIPHPDQL 241
           KP+S+PVIFAGGQ                               AYTIQGQYAIP PD L
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPD-L 239

Query: 242 TKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIP 301
           TKLHQLAMQQ+ F P+   N  F G    + SS  +  + G  +GLDAS   ++HELTIP
Sbjct: 240 TKLHQLAMQQSHF-PMTHGNTGFSG----IESS--SPEVKGYWAGLDASAQTTSHELTIP 292

Query: 302 NDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL 361
           NDLIGCIIGRQG KINEIRQMSGAQIKIAN  EGS++RQ+TITG+ A+ISLAQYLIN RL
Sbjct: 293 NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL 352

Query: 362 TSEVTGMGT 370
           +SE  GMG+
Sbjct: 353 SSETGGMGS 361


>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
          Length = 361

 Score =  485 bits (1248), Expect = e-137
 Identities = 263/369 (71%), Positives = 291/369 (78%), Gaps = 40/369 (10%)

Query: 33  MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
           M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1   MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60

Query: 93  ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
           + GPT+AIFKAFAMI  K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61  LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120

Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRP 212
           KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLESPPKG TIPYRP
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRP 180

Query: 213 KPASTPVIFAGGQ-------------------------------AYTIQGQYAIPHPDQL 241
           KP+S+PVIFAGGQ                               AYTIQGQYAIP PD L
Sbjct: 181 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPD-L 239

Query: 242 TKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIP 301
           TKLHQLAMQQ+ F P+   N  F G +    SS E +       GLDAS   ++HELTIP
Sbjct: 240 TKLHQLAMQQSHF-PMTHGNTGFSGIE---SSSPEVKGYW----GLDASAQTTSHELTIP 291

Query: 302 NDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL 361
           NDLIGCIIGRQG KINEIRQMSGAQIKIAN  EGS++RQ+TITG+ A+ISLAQYLIN RL
Sbjct: 292 NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL 351

Query: 362 TSEVTGMGT 370
           +SE  GMG+
Sbjct: 352 SSETGGMGS 360


>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
          Length = 366

 Score =  481 bits (1239), Expect = e-136
 Identities = 263/373 (70%), Positives = 293/373 (78%), Gaps = 43/373 (11%)

Query: 33  MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
           M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1   MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60

Query: 93  ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
           + GPT+AIFKAFAMI  K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61  LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120

Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE----SPPKGATI 208
           KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE    SPPKG TI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180

Query: 209 PYRPKPASTPVIFAGGQ-------------------------------AYTIQGQYAIPH 237
           PYRPKP+S+PVIFAGGQ                               AYTIQGQYAIP 
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240

Query: 238 PDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHE 297
           PD LTKLHQLAMQQ+ F P+   N  F G    + SS  +  + G  +GLDAS   ++HE
Sbjct: 241 PD-LTKLHQLAMQQSHF-PMTHGNTGFSG----IESS--SPEVKGYWAGLDASAQTTSHE 292

Query: 298 LTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLI 357
           LTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN  EGS++RQ+TITG+ A+ISLAQYLI
Sbjct: 293 LTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 352

Query: 358 NARLTSEVTGMGT 370
           N RL+SE  GMG+
Sbjct: 353 NVRLSSETGGMGS 365


>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
          Length = 365

 Score =  479 bits (1233), Expect = e-135
 Identities = 263/373 (70%), Positives = 291/373 (78%), Gaps = 44/373 (11%)

Query: 33  MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
           M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 1   MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60

Query: 93  ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
           + GPT+AIFKAFAMI  K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 61  LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120

Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE----SPPKGATI 208
           KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE    SPPKG TI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180

Query: 209 PYRPKPASTPVIFAGGQ-------------------------------AYTIQGQYAIPH 237
           PYRPKP+S+PVIFAGGQ                               AYTIQGQYAIP 
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240

Query: 238 PDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHE 297
           PD LTKLHQLAMQQ+ F P+   N  F G +    SS E +       GLDAS   ++HE
Sbjct: 241 PD-LTKLHQLAMQQSHF-PMTHGNTGFSGIE---SSSPEVKGYW----GLDASAQTTSHE 291

Query: 298 LTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLI 357
           LTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN  EGS++RQ+TITG+ A+ISLAQYLI
Sbjct: 292 LTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 351

Query: 358 NARLTSEVTGMGT 370
           N RL+SE  GMG+
Sbjct: 352 NVRLSSETGGMGS 364


>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
          Length = 356

 Score =  423 bits (1088), Expect = e-118
 Identities = 239/364 (65%), Positives = 277/364 (76%), Gaps = 37/364 (10%)

Query: 33  MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
           M++ V+E GLNVTLTIRLLMHGKEVGSIIGKKGE+VK++REESGARINISEGNCPERI+T
Sbjct: 1   MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60

Query: 93  ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
           +TGPT+AIFKAFAMI  K EEDI +SM+NS A S+PPVTLRLVVPA+QCGSLIGKGG KI
Sbjct: 61  LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120

Query: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLES---PPKG--AT 207
           KEIRESTGAQVQVAGDMLPNSTERA+TI+G P ++ +CVKQIC+VMLE+    P+G   T
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180

Query: 208 IPYRPKPASTPVIFAGGQ----------------------AYTIQGQYAIPHPDQLTKLH 245
           IPY+P PAS+PVI AGGQ                      AY+IQGQ+ I  P  L KL+
Sbjct: 181 IPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTI-SPLDLAKLN 239

Query: 246 QLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLI 305
           Q+A QQ+ F  +      F G          +  + G  + LDAS   +THELTIPN+LI
Sbjct: 240 QVARQQSHFAMM-HGGTGFAG------IDSSSPEVKGYWASLDAS-TQTTHELTIPNNLI 291

Query: 306 GCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEV 365
           GCIIGRQG  INEIRQMSGAQIKIAN  EGSS RQ+TITG+ A+ISLAQYLINARL+SE 
Sbjct: 292 GCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE- 350

Query: 366 TGMG 369
            GMG
Sbjct: 351 KGMG 354


>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
          Length = 403

 Score =  379 bits (972), Expect = e-105
 Identities = 198/333 (59%), Positives = 242/333 (72%), Gaps = 25/333 (7%)

Query: 39  EGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTD 98
           E  L++TLT+R+LMHGKEVGSIIGKKGETVK++RE+S ARI ISEG+CPERI TITG T 
Sbjct: 11  EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70

Query: 99  AIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRES 158
           A+F A +MIA+K +ED+  + +N    S+PPVTLRLV+PASQCGSLIGK G+KIKEIRE+
Sbjct: 71  AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130

Query: 159 TGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTP 218
           TGAQVQVAGD+LPNSTERAVT+SG PDAII CV+QIC V+LESPPKGATIPY P  +   
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190

Query: 219 VIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQ 278
           V+ +  Q +++QGQY    P ++TKL QL+    PF     T    P             
Sbjct: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPF----ATPSVVP------------- 233

Query: 279 NLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE 338
                  GLD     S+ E  +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N  EG+ E
Sbjct: 234 -------GLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGE 286

Query: 339 RQITITGTPANISLAQYLINARL-TSEVTGMGT 370
           R +TITG+P +I+LAQYLI A L T++ T  GT
Sbjct: 287 RHVTITGSPVSIALAQYLITACLETAKSTSGGT 319


>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
          Length = 403

 Score =  379 bits (972), Expect = e-105
 Identities = 198/333 (59%), Positives = 242/333 (72%), Gaps = 25/333 (7%)

Query: 39  EGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTD 98
           E  L++TLT+R+LMHGKEVGSIIGKKGETVK++RE+S ARI ISEG+CPERI TITG T 
Sbjct: 11  EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70

Query: 99  AIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRES 158
           A+F A +MIA+K +ED+  + +N    S+PPVTLRLV+PASQCGSLIGK G+KIKEIRE+
Sbjct: 71  AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130

Query: 159 TGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTP 218
           TGAQVQVAGD+LPNSTERAVT+SG PDAII CV+QIC V+LESPPKGATIPY P  +   
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGT 190

Query: 219 VIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQ 278
           V+ +  Q +++QGQY    P ++TKL QL+    PF     T    P             
Sbjct: 191 VLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPF----ATPSVVP------------- 233

Query: 279 NLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSE 338
                  GLD     S+ E  +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N  EG+ E
Sbjct: 234 -------GLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGE 286

Query: 339 RQITITGTPANISLAQYLINARL-TSEVTGMGT 370
           R +TITG+P +I+LAQYLI A L T++ T  GT
Sbjct: 287 RHVTITGSPVSIALAQYLITACLETAKSTSGGT 319


>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
          Length = 424

 Score =  293 bits (750), Expect = 2e-79
 Identities = 169/353 (47%), Positives = 209/353 (59%), Gaps = 80/353 (22%)

Query: 74  ESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLR 133
           +S ARI ISEG+CPERI TITG T A+F A +MIA+K +ED+  + +N    S+PPVTLR
Sbjct: 12  QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 71

Query: 134 LVVPASQCGSLIGKGGSKIK---EIR---------------------------------- 156
           LV+PASQCGSLIGK G+KIK   E+R                                  
Sbjct: 72  LVIPASQCGSLIGKAGTKIKEIREVRGEIYHPQGIRGKGAVVRGVLGLWRPPHLESSEPG 131

Query: 157 ------------------ESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVM 198
                             ++TGAQVQVAGD+LPNSTERAVT+SG PDAII CV+QIC V+
Sbjct: 132 QPFSGLWEQPEVAPVLCLQTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 191

Query: 199 LESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLG 258
           LESPPKGATIPY P  +   V+ +  Q +++QGQY    P ++TKL QL+    PF    
Sbjct: 192 LESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPF---- 247

Query: 259 QTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINE 318
            T    P                    GLD     S+ E  +PNDLIGC+IGRQG+KI+E
Sbjct: 248 ATPSVVP--------------------GLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISE 287

Query: 319 IRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARL-TSEVTGMGT 370
           IRQMSGA IKI N  EG+ ER +TITG+P +I+LAQYLI A L T++ T  GT
Sbjct: 288 IRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGT 340



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 6/90 (6%)

Query: 135 VVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTP--DAIIQCVK 192
           +VP    G +IG+ GSKI EIR+ +GA +++ G+    + ER VTI+G+P   A+ Q + 
Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQAEGAGERHVTITGSPVSIALAQYLI 326

Query: 193 QICVVMLESPPKGATIPYRPKPASTPVIFA 222
             C+   +S   G        PA  P  F+
Sbjct: 327 TACLETAKSTSGGTP---SSAPADLPAPFS 353



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 11/97 (11%)

Query: 57  VGSIIGKKGETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEE 113
           +G +IG++G  + ++R+ SGA I I   +EG   ER VTITG   +I  A  +I    E 
Sbjct: 274 IGCVIGRQGSKISEIRQMSGAHIKIGNQAEG-AGERHVTITGSPVSIALAQYLITACLET 332

Query: 114 DIINS-------MSNSPATSKPPVTLRLVVPASQCGS 143
               S        ++ PA   PP+T     P    G+
Sbjct: 333 AKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT 369


>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score =  106 bits (264), Expect = 4e-23
 Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107
           +R+L+  K  G++IGK G+ +K +R +  A +++ + + PERI++I+   + I +    I
Sbjct: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104

Query: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147
               EE +   + +  ATS+ P+                     LRL++  S  G +IG 
Sbjct: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162

Query: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGAT 207
            G+KIKE+RE+T   +++  +  P+ST+R V I G PD +++C+K I  ++ ESP KG  
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222

Query: 208 IPYRP 212
            PY P
Sbjct: 223 QPYDP 227



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 39/76 (51%), Positives = 47/76 (61%)

Query: 282 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 341
           G+ S  D   P  T ++TIP DL G IIG+ G +I +IR  SGA IKI    EGS +R I
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435

Query: 342 TITGTPANISLAQYLI 357
           TITGT   I  AQYL+
Sbjct: 436 TITGTQDQIQNAQYLL 451



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)

Query: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187
           P +T ++ +P    GS+IGKGG +IK+IR  +GA +++  + L  S +R +TI+GT D I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 58  GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103
           GSIIGK G+ +K++R ESGA I I E      +RI+TITG  D I  A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)

Query: 41  GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R+V I G  
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199

Query: 98  DAIFKAFAMI 107
           D + +   +I
Sbjct: 200 DRVVECIKII 209



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 8/85 (9%)

Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++IS   + I +
Sbjct: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99

Query: 190 CVKQICVVM-----LESPPKGATIP 209
            +K+I   +     L SP   + +P
Sbjct: 100 ILKKIIPTLEEGLQLPSPTATSQLP 124



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 298 LTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANATEGSSERQITITGTPANI 350
           L I   L G IIG +G KI E+R+ +   IK+       S++R + I G P  +
Sbjct: 149 LLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRV 202


>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
           [Homo sapiens]
          Length = 463

 Score =  106 bits (264), Expect = 4e-23
 Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107
           +R+L+  K  G++IGK G+ +K +R +  A +++ + + PERI++I+   + I +    I
Sbjct: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104

Query: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147
               EE +   + +  ATS+ P+                     LRL++  S  G +IG 
Sbjct: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162

Query: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGAT 207
            G+KIKE+RE+T   +++  +  P+ST+R V I G PD +++C+K I  ++ ESP KG  
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222

Query: 208 IPYRP 212
            PY P
Sbjct: 223 QPYDP 227



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 39/76 (51%), Positives = 47/76 (61%)

Query: 282 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 341
           G+ S  D   P  T ++TIP DL G IIG+ G +I +IR  SGA IKI    EGS +R I
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435

Query: 342 TITGTPANISLAQYLI 357
           TITGT   I  AQYL+
Sbjct: 436 TITGTQDQIQNAQYLL 451



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)

Query: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187
           P +T ++ +P    GS+IGKGG +IK+IR  +GA +++  + L  S +R +TI+GT D I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 58  GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103
           GSIIGK G+ +K++R ESGA I I E      +RI+TITG  D I  A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)

Query: 41  GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R+V I G  
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199

Query: 98  DAIFKAFAMI 107
           D + +   +I
Sbjct: 200 DRVVECIKII 209



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 8/85 (9%)

Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++IS   + I +
Sbjct: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99

Query: 190 CVKQICVVM-----LESPPKGATIP 209
            +K+I   +     L SP   + +P
Sbjct: 100 ILKKIIPTLEEGLQLPSPTATSQLP 124



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 298 LTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANATEGSSERQITITGTPANI 350
           L I   L G IIG +G KI E+R+ +   IK+       S++R + I G P  +
Sbjct: 149 LLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRV 202


>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score =  106 bits (264), Expect = 4e-23
 Identities = 59/185 (31%), Positives = 101/185 (54%), Gaps = 22/185 (11%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMI 107
           +R+L+  K  G++IGK G+ +K +R +  A +++ + + PERI++I+   + I +    I
Sbjct: 45  LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104

Query: 108 AYKFEEDIINSMSNSPATSKPPVT--------------------LRLVVPASQCGSLIGK 147
               EE +   + +  ATS+ P+                     LRL++  S  G +IG 
Sbjct: 105 IPTLEEGL--QLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162

Query: 148 GGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGAT 207
            G+KIKE+RE+T   +++  +  P+ST+R V I G PD +++C+K I  ++ ESP KG  
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRA 222

Query: 208 IPYRP 212
            PY P
Sbjct: 223 QPYDP 227



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 39/76 (51%), Positives = 47/76 (61%)

Query: 282 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 341
           G+ S  D   P  T ++TIP DL G IIG+ G +I +IR  SGA IKI    EGS +R I
Sbjct: 376 GRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRII 435

Query: 342 TITGTPANISLAQYLI 357
           TITGT   I  AQYL+
Sbjct: 436 TITGTQDQIQNAQYLL 451



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 25/60 (41%), Positives = 40/60 (66%), Gaps = 1/60 (1%)

Query: 128 PPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAI 187
           P +T ++ +P    GS+IGKGG +IK+IR  +GA +++  + L  S +R +TI+GT D I
Sbjct: 386 PIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI-DEPLEGSEDRIITITGTQDQI 444



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 25/48 (52%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 58  GSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKA 103
           GSIIGK G+ +K++R ESGA I I E      +RI+TITG  D I  A
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNA 447



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 3/70 (4%)

Query: 41  GLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPT 97
           G +    +RLL+H    G IIG KG  +K++RE +   I + +  CP   +R+V I G  
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199

Query: 98  DAIFKAFAMI 107
           D + +   +I
Sbjct: 200 DRVVECIKII 209



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 8/85 (9%)

Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQ 189
           V LR+++ +   G++IGKGG  IK +R    A V V     P   ER ++IS   + I +
Sbjct: 43  VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99

Query: 190 CVKQICVVM-----LESPPKGATIP 209
            +K+I   +     L SP   + +P
Sbjct: 100 ILKKIIPTLEEGLQLPSPTATSQLP 124



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 298 LTIPNDLIGCIIGRQGTKINEIRQMSGAQIKI-ANATEGSSERQITITGTPANI 350
           L I   L G IIG +G KI E+R+ +   IK+       S++R + I G P  +
Sbjct: 149 LLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRV 202


>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
          Length = 492

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 95/348 (27%), Positives = 150/348 (43%), Gaps = 33/348 (9%)

Query: 49  RLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKAF 104
           +L++     G IIGK G TVK + E+SGA + +S+     N  ER+VT++G  + + KA 
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193

Query: 105 AMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGG-- 149
           + I  K +ED             +   ++NS  T  P  +   V+PA+   S     G  
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASGLL 253

Query: 150 --SKIKEIRESTGAQVQVAG-DMLPNSTERAVTIS---GTPDAIIQCVKQICVVMLESPP 203
             + +  +     A    +G D+L  ST      S    T    +         +L +  
Sbjct: 254 GPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSAAASGVLAAVA 313

Query: 204 KGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQ-TNP 262
            GA  P     A+    +AG       G  A P P     L   A+       LG     
Sbjct: 314 AGAN-PAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGSFALAAAANGYLGAGAGG 372

Query: 263 AFPGEKLPLHSSEEAQNLMG---QSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEI 319
              G   PL ++  A    G    +  L A       E+ +P +L+G I+G+ G  + E 
Sbjct: 373 GAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGAILGKGGKTLVEY 432

Query: 320 RQMSGAQIKIANATE---GSSERQITITGTPANISLAQYLINARLTSE 364
           ++++GA+I+I+   E   G+  R++TITG+PA    AQYLI+ R+T E
Sbjct: 433 QELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE 480



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 23/193 (11%)

Query: 35  SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN-----CPER 89
           +K S  G      +++L+     GSIIGK G+T+ ++++E+GA I +S+         ER
Sbjct: 22  TKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 81

Query: 90  IVTITGPTDAIFKAFAMIAYKFEE--------DIINSMSNSPATSKPP---VTLRLVVPA 138
           +  + G  +A+    + IA K  E        +++N +   P T+  P      +L+VP 
Sbjct: 82  VCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQ--PQTTMNPDRAKQAKLIVPN 139

Query: 139 SQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQCVKQIC 195
           S  G +IGKGG+ +K + E +GA VQ++    P   N  ER VT+SG P+ + + V  I 
Sbjct: 140 STAGLIIGKGGATVKAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAIV 197

Query: 196 VVMLESPPKGATI 208
             + E P   + +
Sbjct: 198 QKVQEDPQSSSCL 210



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 48/226 (21%), Positives = 90/226 (39%), Gaps = 72/226 (31%)

Query: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQ 189
           L++++P+   GS+IGKGG  I ++++ TGA ++++   D  P +TE              
Sbjct: 35  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTE-------------- 80

Query: 190 CVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAM 249
              ++C+V                          G A            + L  +H    
Sbjct: 81  ---RVCLVQ-------------------------GTA------------EALNAVHSFIA 100

Query: 250 QQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCII 309
           ++    P   T P             E  N++   + ++    A   +L +PN   G II
Sbjct: 101 EKVREIPQAMTKP-------------EVVNILQPQTTMNPDR-AKQAKLIVPNSTAGLII 146

Query: 310 GRQGTKINEIRQMSGAQIKIANATEGSS--ERQITITGTPANISLA 353
           G+ G  +  + + SGA ++++   EG +  ER +T++G P  +  A
Sbjct: 147 GKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192


>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
           sapiens]
          Length = 572

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 82/348 (23%), Positives = 150/348 (43%), Gaps = 50/348 (14%)

Query: 55  KEVGSIIGKKGETVKKMREESGARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFE 112
           K VG IIG+ GE + +++ ESG +I I+      PER   +TG  ++I +A  ++     
Sbjct: 87  KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLG---- 142

Query: 113 EDIINSMSNSPA----TSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ-VQVAG 167
             I++   N P              +++PAS+ G +IG+GG  IK+++E TG + V +  
Sbjct: 143 -QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQD 201

Query: 168 DMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAY 227
             LP   ++ + I+G    + Q  + +  ++ E         +R           GG   
Sbjct: 202 GPLPTGADKPLRITGDAFKVQQAREMVLEIIREKD----QADFRGVRGDFNSRMGGGSIE 257

Query: 228 TIQGQYAI-----PHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKL-PLHSSEEAQNLM 281
               ++A+      + + + K+   A  +  F P    +P    + + P    + A +++
Sbjct: 258 VSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHII 317

Query: 282 GQ----------SSGLDAS-------------PPASTHEL--TIPNDLIGCIIGRQGTKI 316
            +            GL A+              P    E+  T+P D  G +IG+ G  I
Sbjct: 318 SELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENI 377

Query: 317 NEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQYLINARL 361
             I Q SGA +++      +S+   R+ TI G P  I +A+ LI+ ++
Sbjct: 378 KSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV 425



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 53/181 (29%), Positives = 81/181 (44%), Gaps = 20/181 (11%)

Query: 57  VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKF--- 111
           VG +IG+ GE +KK++ ++G RI     +G  PER   + GP D    A  +I+      
Sbjct: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTA 324

Query: 112 -EEDIINSMSNSPATSKPP-----------VTLRLVVPASQCGSLIGKGGSKIKEIREST 159
            E D    ++ +    +               +   VPA +CG +IGKGG  IK I + +
Sbjct: 325 QERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQS 384

Query: 160 GAQVQVAGDMLPNSTE--RAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPAST 217
           GA V++  +  PNS    R  TI G P   I+  +Q+    +     GA   +   P S 
Sbjct: 385 GAHVELQRNPPPNSDPNLRRFTIRGVPQQ-IEVARQLIDEKVGGTNLGAPGAFGQSPFSQ 443

Query: 218 P 218
           P
Sbjct: 444 P 444



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 65/280 (23%), Positives = 116/280 (41%), Gaps = 28/280 (10%)

Query: 113 EDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN 172
           +D + +   +    +  +T    VP    G +IG+GG +I  I+  +G ++Q+A +    
Sbjct: 61  DDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SG 119

Query: 173 STERAVTISGTPDAIIQCVK---QICVVMLESP------PKGATIPYRPKPASTPVIFAG 223
             ER   ++GTP++I Q  +   QI       P         +TI     PAS   +  G
Sbjct: 120 IPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIG 179

Query: 224 GQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFP-----PLGQTNPAFPGEK-----LPLHS 273
                 +G   I    + T +  + +Q  P P     PL  T  AF  ++     L +  
Sbjct: 180 ------RGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIR 233

Query: 274 SEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANAT 333
            ++  +  G     ++     + E+++P   +G +IGR G  I +I+  +G +I+     
Sbjct: 234 EKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD 293

Query: 334 EGSSERQITITGTPANISLAQYLINARL--TSEVTGMGTL 371
             S ER   + G P     A ++I+  +    E  G G L
Sbjct: 294 GISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGL 333



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 12/126 (9%)

Query: 239 DQLTKLHQLAMQQTPFPPLGQTNP-------AFPGEKLPLHSSEEAQNLMGQSSGLDASP 291
           D L ++ Q+A +    P L  + P        +  +K PL        +  Q   L    
Sbjct: 21  DALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDG-----VGNQLGALVHQR 75

Query: 292 PASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANIS 351
              T E  +P+ ++G IIGR G +I+ I+  SG +I+IA+ + G  ER   +TGTP +I 
Sbjct: 76  TVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIE 135

Query: 352 LAQYLI 357
            A+ L+
Sbjct: 136 QAKRLL 141



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 39/143 (27%), Positives = 72/143 (50%), Gaps = 8/143 (5%)

Query: 50  LLMHGKEVGSIIGKKGETVKKMREESGAR-INISEGNCP---ERIVTITGPTDAIFKAFA 105
           +L+   +VG +IG+ GET+K+++E +G + + I +G  P   ++ + ITG    + +A  
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226

Query: 106 M---IAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQ 162
           M   I  + ++     +     +     ++ + VP    G +IG+ G  IK+I+   G +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286

Query: 163 VQVAGDMLPNSTERAVTISGTPD 185
           +Q   D    S ERA  + G PD
Sbjct: 287 IQFKPDD-GISPERAAQVMGPPD 308


>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
           isoform a [Homo sapiens]
          Length = 599

 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 98/373 (26%), Positives = 160/373 (42%), Gaps = 45/373 (12%)

Query: 11  SVLPHSTLSTLSHHPQPQFGRRM--ESKVSEGGLN----VTLTIRLLMHGKEVGSIIGKK 64
           S +P   +S+ S   + Q G     E   + GG +    +   +R+L+  + VG+IIGK+
Sbjct: 153 SYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKE 212

Query: 65  GETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
           G T+K + +++ +R++I         E+ VTI    +   +A  MI      +I+   ++
Sbjct: 213 GLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL-----EIMQKEAD 267

Query: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVT 179
               ++  + L+++      G LIGK G  +K+I   TG ++ ++   D+   + ER +T
Sbjct: 268 ETKLAE-EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326

Query: 180 ISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPD 239
           + GT +A      +I   + E+                 ++    QA  I G        
Sbjct: 327 VKGTVEACASAEIEIMKKLREA-------------FENDMLAVNQQANLIPGLNLSALGI 373

Query: 240 QLTKLHQLAMQQTPFPPLGQTN--PAFPGEKLPLH----SSEEAQNLMGQSSGLDASPPA 293
             T L  L+      PP G     PA P      H    SS    +  G      + P  
Sbjct: 374 FSTGLSVLS------PPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQ 427

Query: 294 STHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANIS 351
               L IP   +G IIG++G  I ++ + +GA IKIA A EG   SER + ITG P    
Sbjct: 428 EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPA-EGPDVSERMVIITGPPEAQF 486

Query: 352 LAQYLINARLTSE 364
            AQ  I  +L  E
Sbjct: 487 KAQGRIFGKLKEE 499



 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 8/134 (5%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPTDAIFKAF 104
           + L +  + VG+IIGKKG  +K++   +GA I I+    P   ER+V ITGP +A FKA 
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489

Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
             I  K +E+   +  N     K    +R  VP+S  G +IGKGG  + E++  T A+V 
Sbjct: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544

Query: 165 VAGDMLPNSTERAV 178
           V  D  P+  E  +
Sbjct: 545 VPRDQTPDENEEVI 558


>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
           sapiens]
          Length = 507

 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 85/337 (25%), Positives = 141/337 (41%), Gaps = 35/337 (10%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103
           +++++     G IIGK G TVK + E+SGA + +S+     N  ER+VT++G  +   KA
Sbjct: 174 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 233

Query: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGS 150
             +I  K +ED             +   ++NS  T  P      V+P +   + +  G +
Sbjct: 234 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 292

Query: 151 KIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPY 210
            +  +           G+ L   T    T++     +      +           A    
Sbjct: 293 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASA 352

Query: 211 RPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLP 270
            P  A+  ++       +  G  A         L  LA           TN  F G   P
Sbjct: 353 NPAAAAANLLATYASEASASGSTAGGTAGTFA-LGSLAAATAA------TNGYF-GAASP 404

Query: 271 LHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA 330
           L +S     ++G     D S      E+ +P +L+G I+G+ G  + E ++++GA+I+I+
Sbjct: 405 LAASA----ILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQIS 458

Query: 331 NATE---GSSERQITITGTPANISLAQYLINARLTSE 364
              E   G+  R++TITGTPA    AQYLI  R+T E
Sbjct: 459 KKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 495



 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 63/222 (28%), Positives = 105/222 (47%), Gaps = 44/222 (19%)

Query: 27  PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85
           P+ G    +   E G      +++L+     GSIIGK G+T+ ++++E+GA I +S+   
Sbjct: 34  PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90

Query: 86  ----CPERIVTITGPTDAIFKAFAMIAYKFEE-----------------------DIINS 118
                 ER+  I G  +A+      IA K  E                        I  +
Sbjct: 91  FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQT 150

Query: 119 MSNSPATSKP----PVT------LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVA-- 166
           + +SP T+K     P+T      ++++VP S  G +IGKGG+ +K + E +GA VQ++  
Sbjct: 151 LPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK 210

Query: 167 GDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATI 208
            D + N  ER VT+SG P+   + V+ I   + E P  G+ +
Sbjct: 211 PDGI-NLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 251



 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 48/237 (20%)

Query: 132 LRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQ 189
           L++++P+   GS+IGKGG  I ++++ TGA ++++   D  P +TER   I GT +A+  
Sbjct: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111

Query: 190 CVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAM 249
               I   + E P   A    + +P S            +Q Q  + +PD++        
Sbjct: 112 VHGFIAEKIREMPQNVA----KTEPVSI-----------LQPQTTV-NPDRIK------- 148

Query: 250 QQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCII 309
           Q  P  P   T  + P +  P+ +S                  A+  ++ +PN   G II
Sbjct: 149 QTLPSSPT--TTKSSPSD--PMTTSR-----------------ANQVKIIVPNSTAGLII 187

Query: 310 GRQGTKINEIRQMSGAQIKIANATEGSS--ERQITITGTPANISLAQYLINARLTSE 364
           G+ G  +  + + SGA ++++   +G +  ER +T++G P     A  LI  ++  +
Sbjct: 188 GKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQED 244



 Score = 35.4 bits (80), Expect = 0.083
 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)

Query: 268 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 327
           K PL +  EA +    ++G D        ++ IP+   G IIG+ G  I ++++ +GA I
Sbjct: 27  KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83

Query: 328 KIANATE---GSSERQITITGT 346
           K++ + +   G++ER   I GT
Sbjct: 84  KLSKSKDFYPGTTERVCLIQGT 105


>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
           sapiens]
          Length = 483

 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 20/198 (10%)

Query: 27  PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85
           P+ G    +   E G      +++L+     GSIIGK G+T+ ++++E+GA I +S+   
Sbjct: 34  PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90

Query: 86  ----CPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------L 132
                 ER+  I G  +A+      IA K  E   N     P +   P T         +
Sbjct: 91  FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150

Query: 133 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVA--GDMLPNSTERAVTISGTPDAIIQC 190
           +++VP S  G +IGKGG+ +K + E +GA VQ++   D + N  ER VT+SG P+   + 
Sbjct: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQNRKA 209

Query: 191 VKQICVVMLESPPKGATI 208
           V+ I   + E P  G+ +
Sbjct: 210 VELIIQKIQEDPQSGSCL 227



 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 85/337 (25%), Positives = 141/337 (41%), Gaps = 35/337 (10%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103
           +++++     G IIGK G TVK + E+SGA + +S+     N  ER+VT++G  +   KA
Sbjct: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209

Query: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGS 150
             +I  K +ED             +   ++NS  T  P      V+P +   + +  G +
Sbjct: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 268

Query: 151 KIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPY 210
            +  +           G+ L   T    T++     +      +           A    
Sbjct: 269 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASA 328

Query: 211 RPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLP 270
            P  A+  ++       +  G  A         L  LA           TN  F G   P
Sbjct: 329 NPAAAAANLLATYASEASASGSTAGGTAGTFA-LGSLAAATAA------TNGYF-GAASP 380

Query: 271 LHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA 330
           L +S     ++G     D S      E+ +P +L+G I+G+ G  + E ++++GA+I+I+
Sbjct: 381 LAASA----ILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQIS 434

Query: 331 NATE---GSSERQITITGTPANISLAQYLINARLTSE 364
              E   G+  R++TITGTPA    AQYLI  R+T E
Sbjct: 435 KKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 471



 Score = 35.4 bits (80), Expect = 0.083
 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)

Query: 268 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 327
           K PL +  EA +    ++G D        ++ IP+   G IIG+ G  I ++++ +GA I
Sbjct: 27  KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83

Query: 328 KIANATE---GSSERQITITGT 346
           K++ + +   G++ER   I GT
Sbjct: 84  KLSKSKDFYPGTTERVCLIQGT 105


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 93/400 (23%), Positives = 158/400 (39%), Gaps = 88/400 (22%)

Query: 24  HPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINIS- 82
           HP P+     E +V +G                VG IIG+ GE + K++++SG ++ IS 
Sbjct: 138 HPPPRTSMTEEYRVPDG---------------MVGLIIGRGGEQINKIQQDSGCKVQISP 182

Query: 83  -EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATS--------KPPVTLR 133
             G  PER V++TG  +++ KA  M+     +DI++     P           +      
Sbjct: 183 DSGGLPERSVSLTGAPESVQKAKMML-----DDIVSRGRGGPPGQFHDNANGGQNGTVQE 237

Query: 134 LVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN-STERAVTISGTPDAIIQCVK 192
           +++PA + G +IGKGG  IK+++E  G ++ +  D   N + ++ + I G P  + Q  +
Sbjct: 238 IMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACE 297

Query: 193 QICVVMLESPP--------------KGATIPYRPKPASTPVIFAGGQAYTIQ-------- 230
            +  ++ E                  G  +P         +  +G     IQ        
Sbjct: 298 MVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQ 357

Query: 231 -------GQYAIPH----PDQ-------LTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLH 272
                  G   I H    PD+       +  L Q      P PP G   P  PG +    
Sbjct: 358 FKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMP--PGGR---- 411

Query: 273 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANA 332
                    G+  G +  PP      +IP    G +IGR G  +  I Q +GA ++I+  
Sbjct: 412 -------GRGRGQG-NWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ 463

Query: 333 TEGSSE---RQITITGTPANISLAQYLINARLTSEVTGMG 369
              + +   +   I G+P  I  A+ LI  ++   +  +G
Sbjct: 464 LPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLCPVG 503



 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 63/236 (26%), Positives = 99/236 (41%), Gaps = 52/236 (22%)

Query: 18  LSTLSHHPQPQFGRRME--SKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREES 75
           +  L    Q  FG R E  S++  GG++V +          VG +IG+ GE +KK++ ++
Sbjct: 300 MDILRERDQGGFGDRNEYGSRIG-GGIDVPVPRH------SVGVVIGRSGEMIKKIQNDA 352

Query: 76  GARINISE--GNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPAT-------- 125
           G RI   +  G  PE+I  I GP D    A  +I      D++ S+ + P          
Sbjct: 353 GVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARII-----NDLLQSLRSGPPGPPGGPGMP 407

Query: 126 -------------SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPN 172
                          P   +   +P  +CG +IG+GG  +K I + TGA V+++  + PN
Sbjct: 408 PGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPN 467

Query: 173 STE--RAVTISGTPDAIIQCVKQICVVMLESP------------PKGATIPYRPKP 214
                +   I G+P   I   KQ+    +E P            P G   P+ P P
Sbjct: 468 GDPNFKLFIIRGSPQQ-IDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGP 522



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 32/105 (30%), Positives = 60/105 (57%), Gaps = 10/105 (9%)

Query: 264 FPGEKLPLHSSE--EAQNLMGQSSGLDAS------PPAS--THELTIPNDLIGCIIGRQG 313
           F G+K  L   +  E++ L  Q   + +       PP +  T E  +P+ ++G IIGR G
Sbjct: 105 FGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGG 164

Query: 314 TKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 358
            +IN+I+Q SG +++I+  + G  ER +++TG P ++  A+ +++
Sbjct: 165 EQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLD 209


>gi|17402900 far upstream element-binding protein [Homo sapiens]
          Length = 644

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 88/358 (24%), Positives = 149/358 (41%), Gaps = 59/358 (16%)

Query: 57  VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
           VG IIG+ GE + ++++ESG +I I+   G  PER   +TG  +++  A  ++     + 
Sbjct: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLL-----DQ 166

Query: 115 IINSMSNSPA----TSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDML 170
           I+     +P              +++PAS+ G +IGKGG  IK+++E  G ++ +  D  
Sbjct: 167 IVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGP 226

Query: 171 PNS-TERAVTISGTPDAIIQCVKQICVVMLE---------------SPPKGATIPYRPKP 214
            N+  ++ + I+G P  + Q  + +  ++ +                  +G  +P  P+ 
Sbjct: 227 QNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRF 285

Query: 215 ASTPVIFAGGQAY-TIQGQYAIP---HPDQLTKLHQLAMQQTPFPP-------------- 256
           A   VI   G+    IQ    +     PD  T   ++A  Q   PP              
Sbjct: 286 AVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIA--QITGPPDRCQHAAEIITDLL 343

Query: 257 --LGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGT 314
             +   NP  PG         +    MG   GL            +P    G IIG+ G 
Sbjct: 344 RSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGL------QEFNFIVPTGKTGLIIGKGGE 397

Query: 315 KINEIRQMSGAQIKIANATEGSSE---RQITITGTPANISLAQYLINARLTSEVTGMG 369
            I  I Q SGA+I++      +++   +  TI GTP  I  A+ LI  ++   V  +G
Sbjct: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG 455



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 57/188 (30%), Positives = 89/188 (47%), Gaps = 32/188 (17%)

Query: 57  VGSIIGKKGETVKKMREESGARINIS--EGNCPERIVTITGPTDAIFKAFAMIAYKFEED 114
           VG +IG+ GE +KK++ ++G RI     +G  PERI  ITGP D    A  +I      D
Sbjct: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIIT-----D 341

Query: 115 IINSM-SNSPA----------------TSKPPVTLR---LVVPASQCGSLIGKGGSKIKE 154
           ++ S+ + +P                    PP  L+    +VP  + G +IGKGG  IK 
Sbjct: 342 LLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKS 401

Query: 155 IRESTGAQVQVAGDMLPNS--TERAVTISGTPDAIIQCVKQICVVMLESP--PKGATIPY 210
           I + +GA++++  +  PN+    +  TI GTP   I   +Q+    +  P  P G  +P+
Sbjct: 402 ISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQLIEEKIGGPVNPLGPPVPH 460

Query: 211 RPKPASTP 218
            P     P
Sbjct: 461 GPHGVPGP 468



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 34/113 (30%), Positives = 58/113 (51%), Gaps = 11/113 (9%)

Query: 257 LGQTNPAFPGEKLPLHSSEE--AQNLMGQSSGLDASPP---------ASTHELTIPNDLI 305
           L   +  + G+K PL   ++  A+ +  Q+       P           T E  +P+ ++
Sbjct: 53  LNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMV 112

Query: 306 GCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 358
           G IIGR G +I+ I+Q SG +I+IA  + G  ER   +TGTP ++  A+ L++
Sbjct: 113 GFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLD 165



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 61/266 (22%), Positives = 109/266 (40%), Gaps = 37/266 (13%)

Query: 126 SKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDM--LPNSTERAVTISGT 183
           S+  +T    VP    G +IG+GG +I  I++ +G ++Q+A D   LP   ER+  ++GT
Sbjct: 97  SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153

Query: 184 PDAIIQCVKQICVVMLES--PPKGATIPYRPKPASTPVIFAGGQAYTI--QGQYAIPHPD 239
           P++ +Q  K++   ++E   P  G      P  A   ++    +A  +  +G   I    
Sbjct: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212

Query: 240 QLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEA------------------QNLM 281
           +   +  + +Q  P            G+   +  ++E                    + +
Sbjct: 213 ERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRI 272

Query: 282 GQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQI 341
           G + G+D         + IP   +G +IGR G  I +I+  +G +I+       + ER  
Sbjct: 273 GGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIA 323

Query: 342 TITGTPANISLAQYLINARLTSEVTG 367
            ITG P     A  +I   L S   G
Sbjct: 324 QITGPPDRCQHAAEIITDLLRSVQAG 349



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 40/165 (24%), Positives = 78/165 (47%), Gaps = 14/165 (8%)

Query: 50  LLMHGKEVGSIIGKKGETVKKMREESGAR-INISEG---NCPERIVTITGPTDAIFKAFA 105
           +++   + G +IGK GET+K+++E +G + + I +G      ++ + ITG    + +A  
Sbjct: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249

Query: 106 MIAYKFEE-----DIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTG 160
           M+     +     ++ N   +    ++    + + +P    G +IG+ G  IK+I+   G
Sbjct: 250 MVLELIRDQGGFREVRNEYGSRIGGNE---GIDVPIPRFAVGIVIGRNGEMIKKIQNDAG 306

Query: 161 AQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKG 205
            ++Q   D    + ER   I+G PD   Q   +I   +L S   G
Sbjct: 307 VRIQFKPDD-GTTPERIAQITGPPDR-CQHAAEIITDLLRSVQAG 349



 Score = 36.2 bits (82), Expect = 0.049
 Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 5/60 (8%)

Query: 56  EVGSIIGKKGETVKKMREESGARINISEGNCPE-----RIVTITGPTDAIFKAFAMIAYK 110
           + G IIGK GET+K + ++SGARI +     P      ++ TI G    I  A  +I  K
Sbjct: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446


>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
           isoform b [Homo sapiens]
          Length = 556

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 91/367 (24%), Positives = 153/367 (41%), Gaps = 76/367 (20%)

Query: 11  SVLPHSTLSTLSHHPQPQFGRRM--ESKVSEGGLN----VTLTIRLLMHGKEVGSIIGKK 64
           S +P   +S+ S   + Q G     E   + GG +    +   +R+L+  + VG+IIGK+
Sbjct: 153 SYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKE 212

Query: 65  GETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
           G T+K + +++ +R++I         E+ VTI    +   +A  MI      +I+   ++
Sbjct: 213 GLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL-----EIMQKEAD 267

Query: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVT 179
               ++  + L+++      G LIGK G  +K+I   TG ++ ++   D+   + ER +T
Sbjct: 268 ETKLAE-EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326

Query: 180 ISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPD 239
           + GT +A      +I   + E+                          T  G ++  +P 
Sbjct: 327 VKGTVEACASAEIEIMKKLREAFENDML-----------------AVNTHSGYFSSLYPH 369

Query: 240 QLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELT 299
                HQ      PFP                H S   Q ++                L 
Sbjct: 370 -----HQFG----PFPH---------------HHSYPEQEIV---------------NLF 390

Query: 300 IPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISLAQYLI 357
           IP   +G IIG++G  I ++ + +GA IKIA A EG   SER + ITG P     AQ  I
Sbjct: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPA-EGPDVSERMVIITGPPEAQFKAQGRI 449

Query: 358 NARLTSE 364
             +L  E
Sbjct: 450 FGKLKEE 456



 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 8/134 (5%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPTDAIFKAF 104
           + L +  + VG+IIGKKG  +K++   +GA I I+    P   ER+V ITGP +A FKA 
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446

Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
             I  K +E+   +  N     K    +R  VP+S  G +IGKGG  + E++  T A+V 
Sbjct: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501

Query: 165 VAGDMLPNSTERAV 178
           V  D  P+  E  +
Sbjct: 502 VPRDQTPDENEEVI 515


>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
           [Homo sapiens]
          Length = 579

 Score = 76.3 bits (186), Expect = 4e-14
 Identities = 84/328 (25%), Positives = 142/328 (43%), Gaps = 55/328 (16%)

Query: 46  LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGNCPERIVTITGP---TDA 99
           L +RLL+  + VG+IIGK+G T++ + +++ ++I++         E+ +TI      T A
Sbjct: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255

Query: 100 IFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIREST 159
             K+   I +K  +DI              + L+++   +  G LIGK G  +K+I + T
Sbjct: 256 ACKSILEIMHKEAQDI---------KFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306

Query: 160 GAQVQVA--GDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPAST 217
             ++ ++   ++   + ER +T+ G  +   +  ++I   + ES        Y    AS 
Sbjct: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRES--------YENDIASM 358

Query: 218 PVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEA 277
            +     QA+ I G            L+ L +    FPP     P   G   P  +    
Sbjct: 359 NL-----QAHLIPG----------LNLNALGL----FPPTSGMPPPTSG---PPSAMTPP 396

Query: 278 QNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSS 337
                QS          T  L IP   +G IIG+QG  I ++ + +GA IKIA A    +
Sbjct: 397 YPQFEQSE-------TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA 449

Query: 338 E-RQITITGTPANISLAQYLINARLTSE 364
           + R + ITG P     AQ  I  ++  E
Sbjct: 450 KVRMVIITGPPEAQFKAQGRIYGKIKEE 477



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 45/137 (32%), Positives = 73/137 (53%), Gaps = 8/137 (5%)

Query: 45  TLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIF 101
           T T+ L +    VG+IIGK+G+ +K++   +GA I I+    P+   R+V ITGP +A F
Sbjct: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464

Query: 102 KAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGA 161
           KA   I  K +E+   S        +  +   + VP+   G +IGKGG  + E++  + A
Sbjct: 465 KAQGRIYGKIKEENFVS-----PKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519

Query: 162 QVQVAGDMLPNSTERAV 178
           +V V  D  P+  ++ V
Sbjct: 520 EVVVPRDQTPDENDQVV 536



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 1/78 (1%)

Query: 122 SPATSKP-PVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTI 180
           S +  KP  + LRL+VP    G++IGK G+ I+ I + T +++ V       + E+++TI
Sbjct: 187 SVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITI 246

Query: 181 SGTPDAIIQCVKQICVVM 198
             TP+      K I  +M
Sbjct: 247 LSTPEGTSAACKSILEIM 264



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 9/93 (9%)

Query: 270 PLHSSEEAQNLMGQSSGLDASPPASTHE--------LTIPNDLIGCIIGRQGTKINEIRQ 321
           PL      + L  + S    SP + + +        L +P   +G IIG++G  I  I +
Sbjct: 164 PLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITK 223

Query: 322 MSGAQIKI-ANATEGSSERQITITGTPANISLA 353
            + ++I +      G++E+ ITI  TP   S A
Sbjct: 224 QTQSKIDVHRKENAGAAEKSITILSTPEGTSAA 256



 Score = 28.9 bits (63), Expect = 7.8
 Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 4/71 (5%)

Query: 29  FGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE 88
           +G+  E         V L   + +     G +IGK G+TV +++  S A + +     P+
Sbjct: 471 YGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPD 530

Query: 89  R----IVTITG 95
                +V ITG
Sbjct: 531 ENDQVVVKITG 541


>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
           isoform 1 [Homo sapiens]
          Length = 577

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 82/345 (23%), Positives = 146/345 (42%), Gaps = 49/345 (14%)

Query: 26  QPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---S 82
           QP+ G  + +        V + +RLL+  + VG+IIGK+G T++ + +++ ++I++    
Sbjct: 176 QPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKE 235

Query: 83  EGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCG 142
                E+ +++    +    A  MI      +I++  +    T+   V L+++   +  G
Sbjct: 236 NAGAAEKAISVHSTPEGCSSACKMIL-----EIMHKEAKDTKTA-DEVPLKILAHNNFVG 289

Query: 143 SLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAIIQCVKQICVVMLE 200
            LIGK G  +K++ + T  ++ ++   D+   + ER +T+ G   AI  C +    +M  
Sbjct: 290 RLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKG---AIENCCRAEQEIM-- 344

Query: 201 SPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQT 260
              K     Y    A+  +     Q++ I G            L   +    P PP   T
Sbjct: 345 ---KKVREAYENDVAAMSL-----QSHLIPGLNL-----AAVGLFPASSSAVPPPPSSVT 391

Query: 261 NPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIR 320
             A      P  S  +A             P     ++ IP   +G IIG++G  I ++ 
Sbjct: 392 GAA------PYSSFMQA-------------PEQEMVQVFIPAQAVGAIIGKKGQHIKQLS 432

Query: 321 QMSGAQIKIA-NATEGSSERQITITGTPANISLAQYLINARLTSE 364
           + + A IKIA   T  S  R + ITG P     AQ  I  +L  E
Sbjct: 433 RFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 477



 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 8/134 (5%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 104
           +++ +  + VG+IIGKKG+ +K++   + A I I+    P+   R+V ITGP +A FKA 
Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467

Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
             I  K +E+            +  +   + VPAS  G +IGKGG  + E++  T A+V 
Sbjct: 468 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522

Query: 165 VAGDMLPNSTERAV 178
           V  D  P+  ++ +
Sbjct: 523 VPRDQTPDENDQVI 536


>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
           isoform 2 [Homo sapiens]
          Length = 438

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 8/134 (5%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPE---RIVTITGPTDAIFKAF 104
           +++ +  + VG+IIGKKG+ +K++   + A I I+    P+   R+V ITGP +A FKA 
Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328

Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
             I  K +E+            +  +   + VPAS  G +IGKGG  + E++  T A+V 
Sbjct: 329 GRIYGKLKEENFFGPKE-----EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383

Query: 165 VAGDMLPNSTERAV 178
           V  D  P+  ++ +
Sbjct: 384 VPRDQTPDENDQVI 397



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 46/184 (25%), Positives = 79/184 (42%), Gaps = 45/184 (24%)

Query: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNC-----PERIVTITGPTDAIFK 102
           +++L H   VG +IGK+G  +KK+ +++  +I IS         PER +T+ G  +   +
Sbjct: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199

Query: 103 AFAMIAYKFEEDIINSMS----------------------NSPATSKPPVTL-------- 132
           A   I  K  E   N ++                      +S A   PP ++        
Sbjct: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259

Query: 133 ----------RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISG 182
                     ++ +PA   G++IGK G  IK++     A +++A    P+S  R V I+G
Sbjct: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319

Query: 183 TPDA 186
            P+A
Sbjct: 320 PPEA 323



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 57/238 (23%), Positives = 96/238 (40%), Gaps = 40/238 (16%)

Query: 130 VTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVTISGTPDAI 187
           V L+++   +  G LIGK G  +K++ + T  ++ ++   D+   + ER +T+ G  +  
Sbjct: 138 VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENC 197

Query: 188 IQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQL 247
            +  ++I   + E+        Y    A+  +     Q++ I G            L   
Sbjct: 198 CRAEQEIMKKVREA--------YENDVAAMSL-----QSHLIPGLNLAA-----VGLFPA 239

Query: 248 AMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGC 307
           +    P PP   T  A      P  S  +A             P     ++ IP   +G 
Sbjct: 240 SSSAVPPPPSSVTGAA------PYSSFMQA-------------PEQEMVQVFIPAQAVGA 280

Query: 308 IIGRQGTKINEIRQMSGAQIKIA-NATEGSSERQITITGTPANISLAQYLINARLTSE 364
           IIG++G  I ++ + + A IKIA   T  S  R + ITG P     AQ  I  +L  E
Sbjct: 281 IIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338


>gi|145312259 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)

Query: 46  LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104
           + I + +  + V  IIG++G  +K++R+++GARI++ +E    ER++ I+G    + KA 
Sbjct: 53  IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112

Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163
           A I             +   T   PV+ +L VP    G +IG+GG  I+ I +++GA++ 
Sbjct: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159

Query: 164 ---QVAGDMLPNSTERAVTISGT 183
              +  G +L     R + ISGT
Sbjct: 160 CDKESEGTLL---LSRLIKISGT 179



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 297 ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYL 356
           E+ +P + +  IIGRQG  I ++R+ +GA+I +     G  ER + I+G P  +  A+  
Sbjct: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114

Query: 357 INARLT 362
           I+  LT
Sbjct: 115 IHQILT 120



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 2/72 (2%)

Query: 295 THELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISL 352
           + +L++P   +G IIGR G  I  I + SGA+I     +EG+    R I I+GT   ++ 
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185

Query: 353 AQYLINARLTSE 364
           A++LI  +++ +
Sbjct: 186 AKHLILEKVSED 197



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)

Query: 43  NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98
           N  ++ +L +  + VG IIG+ GET++ + + SGA+I     SEG     R++ I+G   
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181

Query: 99  AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133
            +  A  +I  K  ED  +   +++S  T  P   P+++R
Sbjct: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221


>gi|145312270 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)

Query: 46  LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104
           + I + +  + V  IIG++G  +K++R+++GARI++ +E    ER++ I+G    + KA 
Sbjct: 53  IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112

Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163
           A I             +   T   PV+ +L VP    G +IG+GG  I+ I +++GA++ 
Sbjct: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159

Query: 164 ---QVAGDMLPNSTERAVTISGT 183
              +  G +L     R + ISGT
Sbjct: 160 CDKESEGTLL---LSRLIKISGT 179



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 297 ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYL 356
           E+ +P + +  IIGRQG  I ++R+ +GA+I +     G  ER + I+G P  +  A+  
Sbjct: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114

Query: 357 INARLT 362
           I+  LT
Sbjct: 115 IHQILT 120



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 2/72 (2%)

Query: 295 THELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISL 352
           + +L++P   +G IIGR G  I  I + SGA+I     +EG+    R I I+GT   ++ 
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185

Query: 353 AQYLINARLTSE 364
           A++LI  +++ +
Sbjct: 186 AKHLILEKVSED 197



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)

Query: 43  NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98
           N  ++ +L +  + VG IIG+ GET++ + + SGA+I     SEG     R++ I+G   
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181

Query: 99  AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133
            +  A  +I  K  ED  +   +++S  T  P   P+++R
Sbjct: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221


>gi|145312256 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 21/143 (14%)

Query: 46  LTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI-SEGNCPERIVTITGPTDAIFKAF 104
           + I + +  + V  IIG++G  +K++R+++GARI++ +E    ER++ I+G    + KA 
Sbjct: 53  IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAK 112

Query: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQV- 163
           A I             +   T   PV+ +L VP    G +IG+GG  I+ I +++GA++ 
Sbjct: 113 AAI-------------HQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKIT 159

Query: 164 ---QVAGDMLPNSTERAVTISGT 183
              +  G +L     R + ISGT
Sbjct: 160 CDKESEGTLL---LSRLIKISGT 179



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 297 ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYL 356
           E+ +P + +  IIGRQG  I ++R+ +GA+I +     G  ER + I+G P  +  A+  
Sbjct: 56  EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG-DERVLLISGFPVQVCKAKAA 114

Query: 357 INARLT 362
           I+  LT
Sbjct: 115 IHQILT 120



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 2/72 (2%)

Query: 295 THELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISL 352
           + +L++P   +G IIGR G  I  I + SGA+I     +EG+    R I I+GT   ++ 
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185

Query: 353 AQYLINARLTSE 364
           A++LI  +++ +
Sbjct: 186 AKHLILEKVSED 197



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 9/100 (9%)

Query: 43  NVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINI---SEGN-CPERIVTITGPTD 98
           N  ++ +L +  + VG IIG+ GET++ + + SGA+I     SEG     R++ I+G   
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181

Query: 99  AIFKAFAMIAYKFEED--IINSMSNSPATSKP---PVTLR 133
            +  A  +I  K  ED  +   +++S  T  P   P+++R
Sbjct: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVR 221


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,191,978
Number of Sequences: 37866
Number of extensions: 746559
Number of successful extensions: 2351
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 1909
Number of HSP's gapped (non-prelim): 280
length of query: 371
length of database: 18,247,518
effective HSP length: 104
effective length of query: 267
effective length of database: 14,309,454
effective search space: 3820624218
effective search space used: 3820624218
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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