Search of human proteins with 194272204

Search of human proteins with 194272204

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194272204 actin binding LIM protein family, member 2 isoform
5 [Homo sapiens]
         (531 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194272204 actin binding LIM protein family, member 2 isoform ...  1108   0.0  
gi|153792514 actin binding LIM protein family, member 2 isoform ...  1073   0.0  
gi|194272202 actin binding LIM protein family, member 2 isoform ...  1057   0.0  
gi|194272200 actin binding LIM protein family, member 2 isoform ...  1053   0.0  
gi|194272198 actin binding LIM protein family, member 2 isoform ...  1033   0.0  
gi|194272207 actin binding LIM protein family, member 2 isoform ...   971   0.0  
gi|194272196 actin binding LIM protein family, member 2 isoform ...   934   0.0  
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]      546   e-155
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]      546   e-155
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]      531   e-151
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi...   473   e-133
gi|51173717 actin-binding LIM protein 1 isoform s [Homo sapiens]      164   2e-40
gi|170932518 paxillin isoform 3 [Homo sapiens]                        139   6e-33
gi|170932516 paxillin isoform 2 [Homo sapiens]                        139   6e-33
gi|170932514 paxillin isoform 1 [Homo sapiens]                        139   6e-33
gi|221316659 leupaxin isoform 1 [Homo sapiens]                        115   1e-25
gi|4758670 leupaxin isoform 2 [Homo sapiens]                          115   1e-25
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   111   2e-24
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   110   2e-24
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   110   2e-24
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   110   2e-24
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   109   7e-24
gi|109638745 transforming growth factor beta 1 induced transcrip...   108   9e-24
gi|21361591 transforming growth factor beta 1 induced transcript...   108   9e-24
gi|4505001 LIM domain kinase 1 [Homo sapiens]                          99   1e-20
gi|54112385 four and a half LIM domains 3 [Homo sapiens]               97   3e-20
gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Ho...    96   8e-20
gi|166706879 erythrocyte membrane protein band 4.9 isoform 1 [Ho...    96   8e-20
gi|166706875 erythrocyte membrane protein band 4.9 isoform 1 [Ho...    96   8e-20
gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Ho...    94   3e-19

>gi|194272204 actin binding LIM protein family, member 2 isoform 5
           [Homo sapiens]
          Length = 531

 Score = 1108 bits (2866), Expect = 0.0
 Identities = 531/531 (100%), Positives = 531/531 (100%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360

Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKKS 420
           GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKKS
Sbjct: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKKS 420

Query: 421 SWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRI 480
           SWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRI
Sbjct: 421 SWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRI 480

Query: 481 RVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 531
           RVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 481 RVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 531


>gi|153792514 actin binding LIM protein family, member 2 isoform 6
           [Homo sapiens]
          Length = 521

 Score = 1073 bits (2775), Expect = 0.0
 Identities = 520/532 (97%), Positives = 520/532 (97%), Gaps = 12/532 (2%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYG           E
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYG-----------E 349

Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRK-K 419
           GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRK K
Sbjct: 350 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK 409

Query: 420 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNR 479
           SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNR
Sbjct: 410 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNR 469

Query: 480 IRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 531
           IRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 470 IRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 521


>gi|194272202 actin binding LIM protein family, member 2 isoform 4
           [Homo sapiens]
          Length = 559

 Score = 1057 bits (2734), Expect = 0.0
 Identities = 519/570 (91%), Positives = 520/570 (91%), Gaps = 50/570 (8%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYG           E
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYG-----------E 349

Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKKS 420
           GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKKS
Sbjct: 350 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKKS 409

Query: 421 SWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS---------------- 464
           SWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS                
Sbjct: 410 SWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFPYSKSDPLPGHGKN 469

Query: 465 -----------------------QYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEE 501
                                  +YKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEE
Sbjct: 470 GLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEE 529

Query: 502 FQEVFGMSIEEFDRLALWKRNDLKKKALLF 531
           FQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 530 FQEVFGMSIEEFDRLALWKRNDLKKKALLF 559


>gi|194272200 actin binding LIM protein family, member 2 isoform 3
           [Homo sapiens]
          Length = 572

 Score = 1053 bits (2724), Expect = 0.0
 Identities = 520/583 (89%), Positives = 520/583 (89%), Gaps = 63/583 (10%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGE           
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGE----------- 349

Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP-------------------- 400
           GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP                    
Sbjct: 350 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPGSESGRSTPSLSVLSDSKPP 409

Query: 401 --------------------------------AARRSDGEDGSLDQDNRKKSSWLMLKGD 428
                                           AARRSDGEDGSLDQDNRKKSSWLMLKGD
Sbjct: 410 PSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRKKSSWLMLKGD 469

Query: 429 ADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRIRVKLPKDV 488
           ADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRIRVKLPKDV
Sbjct: 470 ADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRIRVKLPKDV 529

Query: 489 DRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 531
           DRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 530 DRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 572


>gi|194272198 actin binding LIM protein family, member 2 isoform 2
           [Homo sapiens]
          Length = 611

 Score = 1033 bits (2671), Expect = 0.0
 Identities = 519/622 (83%), Positives = 520/622 (83%), Gaps = 102/622 (16%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGE           
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGE----------- 349

Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP-------------------- 400
           GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP                    
Sbjct: 350 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPGSESGRSTPSLSVLSDSKPP 409

Query: 401 --------------------------------AARRSDGEDGSLDQDNRKKSSWLMLKGD 428
                                           AARRSDGEDGSLDQDNRKKSSWLMLKGD
Sbjct: 410 PSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRKKSSWLMLKGD 469

Query: 429 ADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS------------------------ 464
           ADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS                        
Sbjct: 470 ADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFPYSKSDPLPGHGKNGLDQRNAN 529

Query: 465 ---------------QYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMS 509
                          +YKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMS
Sbjct: 530 LAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMS 589

Query: 510 IEEFDRLALWKRNDLKKKALLF 531
           IEEFDRLALWKRNDLKKKALLF
Sbjct: 590 IEEFDRLALWKRNDLKKKALLF 611


>gi|194272207 actin binding LIM protein family, member 2 isoform 7
           [Homo sapiens]
          Length = 470

 Score =  971 bits (2509), Expect = 0.0
 Identities = 464/466 (99%), Positives = 465/466 (99%), Gaps = 1/466 (0%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGESPQLLSPTPTE 360

Query: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRK-K 419
           GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRK K
Sbjct: 361 GDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQK 420

Query: 420 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQ 465
           SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS+
Sbjct: 421 SSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 466


>gi|194272196 actin binding LIM protein family, member 2 isoform 1
           [Homo sapiens]
          Length = 645

 Score =  934 bits (2415), Expect = 0.0
 Identities = 489/646 (75%), Positives = 503/646 (77%), Gaps = 116/646 (17%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI--------SHSAGDR--QSYGES 350
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI        S+  GD+  +SY + 
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360

Query: 351 PQLLSPTPTEGDQDDRSYKQCRT----SSPSSTGSVSL---------------------- 384
            +  SP+ T      R     R+    S P+ T SV                        
Sbjct: 361 -RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIP 419

Query: 385 -------GRYTPT--------------SRSPQHYSRP------------------AARRS 405
                  GR TP+               ++P+H+  P                  AARRS
Sbjct: 420 YFRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRS 479

Query: 406 DGEDGSLDQDNRK-KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 464
           DGEDGSLDQDNRK KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS
Sbjct: 480 DGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 539

Query: 465 ---------------------------------------QYKIYPYDSLIVTNRIRVKLP 485
                                                  +YKIYPYDSLIVTNRIRVKLP
Sbjct: 540 RFPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLP 599

Query: 486 KDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 531
           KDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 600 KDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645


>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
          Length = 718

 Score =  546 bits (1407), Expect = e-155
 Identities = 257/416 (61%), Positives = 311/416 (74%), Gaps = 12/416 (2%)

Query: 4   VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
           V+ PQ    P EK     I C+ CG  CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 22  VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 78

Query: 64  VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
           ++ GEY+CTLDYQR+YGTRC  C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 79  IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 138

Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
           FNG++C+CQ C+ P+S  SS   +    +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 139 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 196

Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
           GK+L  EYISKDG PYCE DY   FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 197 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 256

Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKL 303
           MF EGEEMYLQGS++WHP C+Q+ +TE++ + TRTSSESI S P SS  GSP   IYAK+
Sbjct: 257 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKV 316

Query: 304 GGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGD---RQSYGESPQLLSPTPT- 359
             EILDY+DLAA+PK KAIYDI+RPD+I+Y P+ +    D   RQS GESP+ LSPTP+ 
Sbjct: 317 DNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSA 376

Query: 360 EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP-TSRSPQHYSRPAARRSDGEDGSL 412
           EG QD R     R++S  S  S    R  YTP TSRSPQH+ RP    S G +  L
Sbjct: 377 EGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPL 432



 Score =  100 bits (250), Expect = 3e-21
 Identities = 46/65 (70%), Positives = 58/65 (89%)

Query: 467 KIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKK 526
           KI+PY+ L+VTNR R K+ ++VDRTRLERHL+PE F+E+FGMSI+EFDRL LW+RND+KK
Sbjct: 654 KIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKK 713

Query: 527 KALLF 531
           KA LF
Sbjct: 714 KAKLF 718


>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
          Length = 778

 Score =  546 bits (1407), Expect = e-155
 Identities = 257/416 (61%), Positives = 311/416 (74%), Gaps = 12/416 (2%)

Query: 4   VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
           V+ PQ    P EK     I C+ CG  CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 82  VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 138

Query: 64  VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
           ++ GEY+CTLDYQR+YGTRC  C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 139 IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 198

Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
           FNG++C+CQ C+ P+S  SS   +    +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 199 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 256

Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
           GK+L  EYISKDG PYCE DY   FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 257 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 316

Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKL 303
           MF EGEEMYLQGS++WHP C+Q+ +TE++ + TRTSSESI S P SS  GSP   IYAK+
Sbjct: 317 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKV 376

Query: 304 GGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGD---RQSYGESPQLLSPTPT- 359
             EILDY+DLAA+PK KAIYDI+RPD+I+Y P+ +    D   RQS GESP+ LSPTP+ 
Sbjct: 377 DNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSA 436

Query: 360 EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP-TSRSPQHYSRPAARRSDGEDGSL 412
           EG QD R     R++S  S  S    R  YTP TSRSPQH+ RP    S G +  L
Sbjct: 437 EGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPL 492



 Score =  100 bits (250), Expect = 3e-21
 Identities = 46/65 (70%), Positives = 58/65 (89%)

Query: 467 KIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKK 526
           KI+PY+ L+VTNR R K+ ++VDRTRLERHL+PE F+E+FGMSI+EFDRL LW+RND+KK
Sbjct: 714 KIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKK 773

Query: 527 KALLF 531
           KA LF
Sbjct: 774 KAKLF 778


>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
          Length = 746

 Score =  531 bits (1368), Expect = e-151
 Identities = 257/444 (57%), Positives = 311/444 (70%), Gaps = 40/444 (9%)

Query: 4   VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
           V+ PQ    P EK     I C+ CG  CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 22  VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 78

Query: 64  VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
           ++ GEY+CTLDYQR+YGTRC  C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 79  IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 138

Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
           FNG++C+CQ C+ P+S  SS   +    +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 139 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 196

Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
           GK+L  EYISKDG PYCE DY   FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 197 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 256

Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNK----------------------------E 275
           MF EGEEMYLQGS++WHP C+Q+ +TE++ +                             
Sbjct: 257 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFFYSKSLIRRTGRSPSLQP 316

Query: 276 TRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSP 335
           TRTSSESI S P SS  GSP   IYAK+  EILDY+DLAA+PK KAIYDI+RPD+I+Y P
Sbjct: 317 TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEP 376

Query: 336 YISHSAGD---RQSYGESPQLLSPTPT-EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP 389
           + +    D   RQS GESP+ LSPTP+ EG QD R     R++S  S  S    R  YTP
Sbjct: 377 FYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTP 436

Query: 390 -TSRSPQHYSRPAARRSDGEDGSL 412
            TSRSPQH+ RP    S G +  L
Sbjct: 437 TTSRSPQHFHRPGNEPSSGRNSPL 460



 Score =  100 bits (250), Expect = 3e-21
 Identities = 46/65 (70%), Positives = 58/65 (89%)

Query: 467 KIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKK 526
           KI+PY+ L+VTNR R K+ ++VDRTRLERHL+PE F+E+FGMSI+EFDRL LW+RND+KK
Sbjct: 682 KIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKK 741

Query: 527 KALLF 531
           KA LF
Sbjct: 742 KAKLF 746


>gi|7662330 actin binding LIM protein family, member 3 [Homo
           sapiens]
          Length = 683

 Score =  473 bits (1216), Expect = e-133
 Identities = 241/453 (53%), Positives = 307/453 (67%), Gaps = 26/453 (5%)

Query: 16  KSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDY 75
           +  S  I C  CG+ CKGEV+RV + +FHI+CF C+ CGC LA+ GFF +  EYICT DY
Sbjct: 15  RGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDY 74

Query: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135
           Q+LYGTRC SC  FI GEV+SALG+TYHP CFVC++CR PFP GD+VTF+GKEC+CQ CS
Sbjct: 75  QQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCS 134

Query: 136 LPVSVGSSAHLS-QGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISK 194
              S+ SS  +  +G   C GC  EIK+GQ+L+ALDK WH+ CFKC++C  +L  EYISK
Sbjct: 135 Q--SMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGEYISK 192

Query: 195 DGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQ 254
           DG+PYCE+DYHA+FGI+C++C++YI+GRVLEAG KHYHP+CA CVRC QMF EGEEMYL 
Sbjct: 193 DGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLT 252

Query: 255 GSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLA 314
           GS +WHP C+QAAR E + K  RTS  SI   P  S+ GSP+RVI AK+  EIL+Y+DLA
Sbjct: 253 GSEVWHPICKQAARAEKKLKHRRTSETSI--SPPGSSIGSPNRVICAKVDNEILNYKDLA 310

Query: 315 ALPKSKAIYDIDRPDMISYSP---YISHSAGDRQSYGESPQLLSPTPTEGDQDDRSYKQC 371
           ALPK K+IY++ RPD+ISY P   Y+S    +R  YGES   LSP  ++   ++   +Q 
Sbjct: 311 ALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPY-SQDIYENLDLRQR 369

Query: 372 RTSSPSSTGSVSLGR--YTPT-SRSPQHYSR--PAARRSDGEDGSLDQDNRKKSSWLMLK 426
           R SSP    S +  R   +PT SRSP HY R  P + RS      LD  +   +S+   K
Sbjct: 370 RASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSSTPTSYQAPK 429

Query: 427 ------GDADTRTNSP------DLDTQSLSHSS 447
                 GD++     P      DL T + S +S
Sbjct: 430 HFHIPAGDSNIYRKPPIYKRHGDLSTATKSKTS 462


>gi|51173717 actin-binding LIM protein 1 isoform s [Homo sapiens]
          Length = 455

 Score =  164 bits (415), Expect = 2e-40
 Identities = 96/192 (50%), Positives = 117/192 (60%), Gaps = 35/192 (18%)

Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNK----------------------------E 275
           MF EGEEMYLQGS++WHP C+Q+ +TE++ +                             
Sbjct: 1   MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFFYSKSLIRRTGRSPSLQP 60

Query: 276 TRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSP 335
           TRTSSESI S P SS  GSP   IYAK+  EILDY+DLAA+PK KAIYDI+RPD+I+Y P
Sbjct: 61  TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEP 120

Query: 336 YISHSAGD---RQSYGESPQLLSPTPT-EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP 389
           + +    D   RQS GESP+ LSPTP+ EG QD R     R++S  S  S    R  YTP
Sbjct: 121 FYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTP 180

Query: 390 -TSRSPQHYSRP 400
            TSRSPQH+ RP
Sbjct: 181 TTSRSPQHFHRP 192



 Score =  100 bits (250), Expect = 3e-21
 Identities = 46/65 (70%), Positives = 58/65 (89%)

Query: 467 KIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKK 526
           KI+PY+ L+VTNR R K+ ++VDRTRLERHL+PE F+E+FGMSI+EFDRL LW+RND+KK
Sbjct: 391 KIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKK 450

Query: 527 KALLF 531
           KA LF
Sbjct: 451 KAKLF 455


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  139 bits (350), Expect = 6e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404



 Score = 30.0 bits (66), Expect = 5.5
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  139 bits (350), Expect = 6e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537



 Score = 30.0 bits (66), Expect = 5.5
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  139 bits (350), Expect = 6e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 417 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 466

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 467 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 524

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 525 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 571



 Score = 30.0 bits (66), Expect = 5.5
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score =  115 bits (287), Expect = 1e-25
 Identities = 68/226 (30%), Positives = 99/226 (43%), Gaps = 13/226 (5%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C +C     G+V+    + +H + FVC  C  ++    FF R G   C  DY +L+  RC
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
             C   I  +V++A+ +T+HP+ F C+ C   F         G E   +K   P      
Sbjct: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC--RK 265

Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEA 202
             L+     CGGC   +     L A+D  WH  CF C  C        +   DG P+CE 
Sbjct: 266 DFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCEL 324

Query: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
            YH + G  C  C + ITGR + A    +HP   +C  C    ++G
Sbjct: 325 HYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 370



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C SC + I G+V+ ALG+++HP+ FVC  C+            G     ++  L      
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 207

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYCE 201
              L      C  C   I + + L A+++ WH   F C  CG++  AE +  KD  PYC 
Sbjct: 208 YHQLFSP--RCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCR 264

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQG 255
            D+ A F  +C  C + +    L A +  +HP C +C  C   F+ G    L G
Sbjct: 265 KDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 318



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 40/111 (36%), Positives = 47/111 (42%), Gaps = 1/111 (0%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C  C        L   D  +H +CFVC  C    + G FF   G   C L Y    GT C
Sbjct: 275 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLC 334

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
             C Q I G  +SA+G  +HP+ FVCA C      G     N K   CQ C
Sbjct: 335 HGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDK-TYCQPC 384



 Score = 33.1 bits (74), Expect = 0.65
 Identities = 16/57 (28%), Positives = 26/57 (45%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ CG    G  +      FH + FVC  C   L++G F  +  +  C   + +L+
Sbjct: 333 LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score =  115 bits (287), Expect = 1e-25
 Identities = 68/226 (30%), Positives = 99/226 (43%), Gaps = 13/226 (5%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C +C     G+V+    + +H + FVC  C  ++    FF R G   C  DY +L+  RC
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 211

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
             C   I  +V++A+ +T+HP+ F C+ C   F         G E   +K   P      
Sbjct: 212 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC--RK 260

Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEA 202
             L+     CGGC   +     L A+D  WH  CF C  C        +   DG P+CE 
Sbjct: 261 DFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCEL 319

Query: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
            YH + G  C  C + ITGR + A    +HP   +C  C    ++G
Sbjct: 320 HYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 365



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C SC + I G+V+ ALG+++HP+ FVC  C+            G     ++  L      
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 202

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYCE 201
              L      C  C   I + + L A+++ WH   F C  CG++  AE +  KD  PYC 
Sbjct: 203 YHQLFSP--RCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCR 259

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQG 255
            D+ A F  +C  C + +    L A +  +HP C +C  C   F+ G    L G
Sbjct: 260 KDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 313



 Score = 75.9 bits (185), Expect = 9e-14
 Identities = 40/111 (36%), Positives = 47/111 (42%), Gaps = 1/111 (0%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C  C        L   D  +H +CFVC  C    + G FF   G   C L Y    GT C
Sbjct: 270 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLC 329

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
             C Q I G  +SA+G  +HP+ FVCA C      G     N K   CQ C
Sbjct: 330 HGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDK-TYCQPC 379



 Score = 33.1 bits (74), Expect = 0.65
 Identities = 16/57 (28%), Positives = 26/57 (45%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ CG    G  +      FH + FVC  C   L++G F  +  +  C   + +L+
Sbjct: 328 LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  111 bits (277), Expect = 2e-24
 Identities = 83/295 (28%), Positives = 116/295 (39%), Gaps = 61/295 (20%)

Query: 6   QPQAAPSPLEKSPSTAILCNTCGNVCKGE------VLRVQDKYFHIKCFVCKACGCDLAE 59
           Q + +P P   + S A+    C   C+        ++    + +H  CFVC  C     E
Sbjct: 18  QHRQSPPPATGNMSDALANAVCQR-CQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPE 76

Query: 60  GGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVC------- 112
           G F+  +G   C  D+Q L+   C SC +FI G V+ A+   +HP CF C +C       
Sbjct: 77  GLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADL 136

Query: 113 --------RLPFPPGDRVTFNG-KECMCQKCSL-----PVSVGSSA-------------- 144
                    L  P  +R    G  + +CQ+C L     P+   S A              
Sbjct: 137 GFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 196

Query: 145 -----------------HLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-L 186
                            H   G+  CG C   I+ G+ + AL K WH+  F C  C K  
Sbjct: 197 LTAEARELKGELYCLPCHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPF 255

Query: 187 LNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
           L   +  K GL YCE  Y+  FG  C +C   I G V+ A  K +  SC  C  C
Sbjct: 256 LGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 310



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 32/112 (28%), Positives = 54/112 (48%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C    +G V+    K +H++ FVC  C         + ++G   C   Y +L+G  
Sbjct: 221 ICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDV 280

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
           C++C   IEG+VVSAL K +   CF C+ C       ++      + +C++C
Sbjct: 281 CYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRC 332



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 173 WHLGCFKCKSCGKLL-NAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHY 231
           +H  CF C  C +      +   +G  YCE D+   F   C SC ++I GRV++A   ++
Sbjct: 60  YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNW 119

Query: 232 HPSCALCVRCGQMFAE 247
           HP C  C  C    A+
Sbjct: 120 HPGCFRCELCDVELAD 135


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  110 bits (276), Expect = 2e-24
 Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
           C +CG    G V++  +  +H  CF C+ C  +LA+ GF    G ++C   + R     L
Sbjct: 98  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157

Query: 79  YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
               C  C   I+ + +      YHPD F C  C      G  +T   +E   +   LP 
Sbjct: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 210

Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
                 H   G+  CG C   I+ G+ + AL K WH+  F C  C K  L   +  K GL
Sbjct: 211 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 264

Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
            YCE  Y+  FG  C +C   I G V+ A  K +  SC  C  C
Sbjct: 265 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 308



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C  V   + L  +   +H   F C  CG +L      ++ GE  C   + ++    
Sbjct: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 219

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C +C + IEG VV+ALGK +H + FVCA C  PF  G R         C+          
Sbjct: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 268

Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
             H +Q     C  C + +  G  + AL+K W + CF C +C     L  +++  D  P 
Sbjct: 269 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 326

Query: 200 CEADY 204
           C+  Y
Sbjct: 327 CKRCY 331



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)

Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
           VC  C+  F P +R+  +  E       +C +C  P   G            H  Q L +
Sbjct: 36  VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 95

Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
             CG CG E   G+ + A++ +WH GCF+C+ C  +L +  ++   G   C   ++ +  
Sbjct: 96  PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154

Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
                  C  C   I  + L      YHP    C  CG ++ AE  E+
Sbjct: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 202


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  110 bits (276), Expect = 2e-24
 Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
           C +CG    G V++  +  +H  CF C+ C  +LA+ GF    G ++C   + R     L
Sbjct: 71  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 130

Query: 79  YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
               C  C   I+ + +      YHPD F C  C      G  +T   +E   +   LP 
Sbjct: 131 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 183

Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
                 H   G+  CG C   I+ G+ + AL K WH+  F C  C K  L   +  K GL
Sbjct: 184 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 237

Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
            YCE  Y+  FG  C +C   I G V+ A  K +  SC  C  C
Sbjct: 238 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 281



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C  V   + L  +   +H   F C  CG +L      ++ GE  C   + ++    
Sbjct: 134 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 192

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C +C + IEG VV+ALGK +H + FVCA C  PF  G R         C+          
Sbjct: 193 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 241

Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
             H +Q     C  C + +  G  + AL+K W + CF C +C     L  +++  D  P 
Sbjct: 242 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 299

Query: 200 CEADY 204
           C+  Y
Sbjct: 300 CKRCY 304



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)

Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
           VC  C+  F P +R+  +  E       +C +C  P   G            H  Q L +
Sbjct: 9   VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 68

Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
             CG CG E   G+ + A++ +WH GCF+C+ C  +L +  ++   G   C   ++ +  
Sbjct: 69  PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 127

Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
                  C  C   I  + L      YHP    C  CG ++ AE  E+
Sbjct: 128 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 175


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  110 bits (276), Expect = 2e-24
 Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
           C +CG    G V++  +  +H  CF C+ C  +LA+ GF    G ++C   + R     L
Sbjct: 76  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 135

Query: 79  YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
               C  C   I+ + +      YHPD F C  C      G  +T   +E   +   LP 
Sbjct: 136 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 188

Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
                 H   G+  CG C   I+ G+ + AL K WH+  F C  C K  L   +  K GL
Sbjct: 189 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 242

Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
            YCE  Y+  FG  C +C   I G V+ A  K +  SC  C  C
Sbjct: 243 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 286



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C  V   + L  +   +H   F C  CG +L      ++ GE  C   + ++    
Sbjct: 139 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 197

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C +C + IEG VV+ALGK +H + FVCA C  PF  G R         C+          
Sbjct: 198 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 246

Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
             H +Q     C  C + +  G  + AL+K W + CF C +C     L  +++  D  P 
Sbjct: 247 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 304

Query: 200 CEADY 204
           C+  Y
Sbjct: 305 CKRCY 309



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)

Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
           VC  C+  F P +R+  +  E       +C +C  P   G            H  Q L +
Sbjct: 14  VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 73

Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
             CG CG E   G+ + A++ +WH GCF+C+ C  +L +  ++   G   C   ++ +  
Sbjct: 74  PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 132

Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
                  C  C   I  + L      YHP    C  CG ++ AE  E+
Sbjct: 133 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 180


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  109 bits (272), Expect = 7e-24
 Identities = 76/282 (26%), Positives = 114/282 (40%), Gaps = 61/282 (21%)

Query: 19  STAILCNTCGNVCKG------EVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICT 72
           + A+   TC   CKG      +++    + +H +CFVC  C     EG F+  +G   C 
Sbjct: 2   ANALASATCER-CKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60

Query: 73  LDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCR---------------LPFP 117
            D+Q L+   C  C +FI G V+ A+  ++HP+CF C +C+               L  P
Sbjct: 61  HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120

Query: 118 PGDRVTFNG-KECMCQKCSLPV--------------------SVGSS------------- 143
             +R    G  + +CQKC   +                    + G               
Sbjct: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180

Query: 144 ---AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPY 199
               H   G+  CG C   I+ G+ + A+ K WH+  F C  C K  L   +  + GL Y
Sbjct: 181 CLPCHDKMGVPICGACRRPIE-GRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAY 239

Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
           CE  Y+  FG  C  C + I G V+ A  K +  +C  C  C
Sbjct: 240 CETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTC 281



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 35/112 (31%), Positives = 56/112 (50%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C    +G V+    K +H++ FVC  C         + R+G   C   Y +L+G  
Sbjct: 192 ICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDV 251

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
           CF C++ IEG+VVSAL K +  +CF C+ C       ++      + +C+KC
Sbjct: 252 CFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKC 303



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 173 WHLGCFKCKSCGKLL-NAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHY 231
           +H  CF C  C +      +   +G  YCE D+   F   C  C ++I GRV++A    +
Sbjct: 31  YHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSW 90

Query: 232 HPSCALCVRCGQMFAE 247
           HP C  C  C ++ A+
Sbjct: 91  HPECFRCDLCQEVLAD 106


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  108 bits (271), Expect = 9e-24
 Identities = 70/242 (28%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           LC +C     G+V+    + +H + FVC  C   L    FF + G   C   Y   +  R
Sbjct: 227 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 286

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKE--CMCQKCSLPVSV 140
           C  C+Q I  ++V+ALG  +HP+ F C  C  PF  GD   F+ +E    C++  L +  
Sbjct: 287 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHEREGRPYCRRDFLQLFA 343

Query: 141 GSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPY 199
                       C GC   I +   + AL   WH  CF C+ C        +   +G P 
Sbjct: 344 ----------PRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 392

Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
           CE  +HA+ G  C +C   +TGR + A  + +HP    C  C +   +G      G    
Sbjct: 393 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 452

Query: 260 HP 261
            P
Sbjct: 453 QP 454



 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 53/187 (28%), Positives = 83/187 (44%), Gaps = 13/187 (6%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C  C    + +++     ++H + F C +CG    + GF  R+G   C  D+ +L+  RC
Sbjct: 287 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 346

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
             C   I    +SAL   +HPDCFVC  C  PF  G      G+  +C+         + 
Sbjct: 347 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRP-LCE---------NH 396

Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCEA 202
            H  +G   C  CG  +  G+ + AL + +H   F C  C + L    +  + G PYC+ 
Sbjct: 397 FHARRG-SLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 454

Query: 203 DYHAKFG 209
            +   FG
Sbjct: 455 CFLKLFG 461



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 19/58 (32%), Positives = 26/58 (44%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYG 80
           LC TCG    G  +    + FH   F C  C   L +G F  R G+  C   + +L+G
Sbjct: 404 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 461


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  108 bits (271), Expect = 9e-24
 Identities = 70/242 (28%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           LC +C     G+V+    + +H + FVC  C   L    FF + G   C   Y   +  R
Sbjct: 210 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKE--CMCQKCSLPVSV 140
           C  C+Q I  ++V+ALG  +HP+ F C  C  PF  GD   F+ +E    C++  L +  
Sbjct: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHEREGRPYCRRDFLQLFA 326

Query: 141 GSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPY 199
                       C GC   I +   + AL   WH  CF C+ C        +   +G P 
Sbjct: 327 ----------PRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 375

Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
           CE  +HA+ G  C +C   +TGR + A  + +HP    C  C +   +G      G    
Sbjct: 376 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 435

Query: 260 HP 261
            P
Sbjct: 436 QP 437



 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 53/187 (28%), Positives = 83/187 (44%), Gaps = 13/187 (6%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C  C    + +++     ++H + F C +CG    + GF  R+G   C  D+ +L+  RC
Sbjct: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 329

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
             C   I    +SAL   +HPDCFVC  C  PF  G      G+  +C+         + 
Sbjct: 330 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRP-LCE---------NH 379

Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCEA 202
            H  +G   C  CG  +  G+ + AL + +H   F C  C + L    +  + G PYC+ 
Sbjct: 380 FHARRG-SLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 437

Query: 203 DYHAKFG 209
            +   FG
Sbjct: 438 CFLKLFG 444



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 19/58 (32%), Positives = 26/58 (44%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYG 80
           LC TCG    G  +    + FH   F C  C   L +G F  R G+  C   + +L+G
Sbjct: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444


>gi|4505001 LIM domain kinase 1 [Homo sapiens]
          Length = 647

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 42/98 (42%), Positives = 57/98 (58%), Gaps = 1/98 (1%)

Query: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
           C  CG  I +GQ L AL+  WH  CF+C  C   L+ +Y  KDG  +C+ DY A++G  C
Sbjct: 25  CASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARYGESC 84

Query: 213 DSCEKYIT-GRVLEAGEKHYHPSCALCVRCGQMFAEGE 249
             C + IT G V+ AGE  YHP C +C+ CG    +G+
Sbjct: 85  HGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGD 122



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 48/172 (27%), Positives = 70/172 (40%), Gaps = 36/172 (20%)

Query: 23  LCNTCGN-VCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
           +C +CG  +  G+ L+  +  +H  CF C  C   L+   ++ + G+  C  DY   YG 
Sbjct: 24  VCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQ-YYEKDGQLFCKKDYWARYGE 82

Query: 82  RCFSC-DQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTF-NGKECMCQKC----- 134
            C  C +Q  +G V+ A    YHP+CF+C  C      GD  T     +  C  C     
Sbjct: 83  SCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTV 142

Query: 135 ---------------SLP-----VSVGSSAHLSQGL-------RSCGGCGTE 159
                           LP     VS+ +S+H  +GL           GCGTE
Sbjct: 143 VTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTE 194



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 13/106 (12%)

Query: 83  CFSCDQFI-EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVG 141
           C SC Q I +G+ + AL   +H DCF C  C        +      +  C+K        
Sbjct: 25  CASCGQRIYDGQYLQALNADWHADCFRCCDCSASL--SHQYYEKDGQLFCKK-------- 74

Query: 142 SSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLL 187
              + ++   SC GC  +I  G  +VA +  +H  CF C +CG  +
Sbjct: 75  --DYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFI 118


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score = 97.4 bits (241), Expect = 3e-20
 Identities = 67/255 (26%), Positives = 107/255 (41%), Gaps = 34/255 (13%)

Query: 25  NTCGNVCK---------GEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDY 75
           NT  N C             L  +D++FH  CF C  C   LA+  F  +  E +C   Y
Sbjct: 34  NTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCY 93

Query: 76  QRLYGTRCFSCDQFI--EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQK 133
              + ++C +C + +      +   G+T+H  CF+C+ C  P      V   G    C  
Sbjct: 94  CSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAH-YCVP 152

Query: 134 CSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYI 192
           C          + ++    C  C   +  G  +   D+ WH  C  C  C   L   ++ 
Sbjct: 153 C----------YENKFAPRCARCSKTLTQG-GVTYRDQPWHRECLVCTGCQTPLAGQQFT 201

Query: 193 SKDGLPYCEADYHAKFGIRCDSCEKYIT----GRVLEAGEKHYHPSCALCVRC-----GQ 243
           S+D  PYC A +   F  +C SC++ I     G+ +   ++H+H +C  C RC     GQ
Sbjct: 202 SRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQ 261

Query: 244 MFA-EGEEMYLQGSS 257
            F  +G+++  QG S
Sbjct: 262 GFVPDGDQVLCQGCS 276



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 54/212 (25%), Positives = 77/212 (36%), Gaps = 20/212 (9%)

Query: 48  FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI--EGEVVSALGKTYHPD 105
           F C  C   L    +        C   Y   +   C  C Q I  +   +    + +H  
Sbjct: 5   FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64

Query: 106 CFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNG-Q 164
           CF C  C+      +  T    E +C  C        SA  SQ    C  CG  +  G +
Sbjct: 65  CFRCCRCQRSL-ADEPFTCQDSELLCNDCY------CSAFSSQ----CSACGETVMPGSR 113

Query: 165 ALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEADYHAKFGIRCDSCEKYITGRV 223
            L    + WH  CF C  C + L +  ++   G  YC   Y  KF  RC  C K +T   
Sbjct: 114 KLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG 173

Query: 224 LEAGEKHYHPSCALCVRC-----GQMFAEGEE 250
           +   ++ +H  C +C  C     GQ F   +E
Sbjct: 174 VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDE 205



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 42/175 (24%), Positives = 68/175 (38%), Gaps = 10/175 (5%)

Query: 24  CNTCGNVCK--GEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
           C+ CG         L    + +H  CF+C  C   L    F   +G + C   Y+  +  
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160

Query: 82  RCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVG 141
           RC  C + +    V+   + +H +C VC  C+ P   G + T   ++  C  C   +   
Sbjct: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPL-AGQQFTSRDEDPYCVACFGELFAP 219

Query: 142 SSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDG 196
             +   + +   GG       G+ +   D+HWH  CF C  C   L  +    DG
Sbjct: 220 KCSSCKRPIVGLGG-------GKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDG 267



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/122 (23%), Positives = 38/122 (31%), Gaps = 36/122 (29%)

Query: 178 FKCKSCGK-LLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYI--TGRVLEAGEKHYHPS 234
           F C  C + L   +YI  D  PYC   Y   F   C  C++ I    R L   ++H+H  
Sbjct: 5   FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64

Query: 235 CALCVRCGQMFAE---------------------------------GEEMYLQGSSIWHP 261
           C  C RC +  A+                                 G      G   WH 
Sbjct: 65  CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHE 124

Query: 262 AC 263
            C
Sbjct: 125 HC 126


>gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Homo
           sapiens]
          Length = 405

 Score = 95.9 bits (237), Expect = 8e-20
 Identities = 46/67 (68%), Positives = 53/67 (79%)

Query: 465 QYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDL 524
           + KIYPY+ L+VTN+ R KLP  VDR RLERHLS E+F  VF MS EEF +LALWKRN+L
Sbjct: 339 EQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNEL 398

Query: 525 KKKALLF 531
           KKKA LF
Sbjct: 399 KKKASLF 405



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 74/259 (28%), Positives = 108/259 (41%), Gaps = 19/259 (7%)

Query: 270 EDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPD 329
           E   K+  TS  S+     SS  GSPS ++ AK+  ++L Y+DLAA+PK KAI DI+RPD
Sbjct: 2   ERLQKQPLTSPGSVSPSRDSSVPGSPSSIV-AKMDNQVLGYKDLAAIPKDKAILDIERPD 60

Query: 330 MISYSPYISHSAGDRQSYGES-PQLLSPTPTEGDQDDRSYKQCRTSSPSSTGSVSLGRYT 388
           ++ Y P+ ++S  +      S  + LSP  T        +   R  SP      S  R T
Sbjct: 61  LMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWADSR--SPGIISQASAPRTT 118

Query: 389 PTSR-SPQHYSRPAARRSDGEDGSLDQDNRKKSSWLMLKGDADTRTNSPDLDTQSLSHSS 447
            T R S  H+  P   R D          +++ S   + G   T+    DL  +S    +
Sbjct: 119 GTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRES---VGGSPQTKHLIEDLIIESSKFPA 175

Query: 448 GTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFG 507
               DP Q        + Y   P    +V    R        + +  R  + EE +E   
Sbjct: 176 AQPPDPNQPA---KIETDYWPCPPSLAVVETEWR--------KRKASRRGAEEEEEEEDD 224

Query: 508 MSIEEFDRLALWKRNDLKK 526
            S EE   L   +R +L K
Sbjct: 225 DSGEEMKALRERQREELSK 243


>gi|166706879 erythrocyte membrane protein band 4.9 isoform 1 [Homo
           sapiens]
          Length = 405

 Score = 95.9 bits (237), Expect = 8e-20
 Identities = 46/67 (68%), Positives = 53/67 (79%)

Query: 465 QYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDL 524
           + KIYPY+ L+VTN+ R KLP  VDR RLERHLS E+F  VF MS EEF +LALWKRN+L
Sbjct: 339 EQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNEL 398

Query: 525 KKKALLF 531
           KKKA LF
Sbjct: 399 KKKASLF 405



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 74/259 (28%), Positives = 108/259 (41%), Gaps = 19/259 (7%)

Query: 270 EDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPD 329
           E   K+  TS  S+     SS  GSPS ++ AK+  ++L Y+DLAA+PK KAI DI+RPD
Sbjct: 2   ERLQKQPLTSPGSVSPSRDSSVPGSPSSIV-AKMDNQVLGYKDLAAIPKDKAILDIERPD 60

Query: 330 MISYSPYISHSAGDRQSYGES-PQLLSPTPTEGDQDDRSYKQCRTSSPSSTGSVSLGRYT 388
           ++ Y P+ ++S  +      S  + LSP  T        +   R  SP      S  R T
Sbjct: 61  LMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWADSR--SPGIISQASAPRTT 118

Query: 389 PTSR-SPQHYSRPAARRSDGEDGSLDQDNRKKSSWLMLKGDADTRTNSPDLDTQSLSHSS 447
            T R S  H+  P   R D          +++ S   + G   T+    DL  +S    +
Sbjct: 119 GTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRES---VGGSPQTKHLIEDLIIESSKFPA 175

Query: 448 GTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFG 507
               DP Q        + Y   P    +V    R        + +  R  + EE +E   
Sbjct: 176 AQPPDPNQPA---KIETDYWPCPPSLAVVETEWR--------KRKASRRGAEEEEEEEDD 224

Query: 508 MSIEEFDRLALWKRNDLKK 526
            S EE   L   +R +L K
Sbjct: 225 DSGEEMKALRERQREELSK 243


>gi|166706875 erythrocyte membrane protein band 4.9 isoform 1 [Homo
           sapiens]
          Length = 405

 Score = 95.9 bits (237), Expect = 8e-20
 Identities = 46/67 (68%), Positives = 53/67 (79%)

Query: 465 QYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDL 524
           + KIYPY+ L+VTN+ R KLP  VDR RLERHLS E+F  VF MS EEF +LALWKRN+L
Sbjct: 339 EQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNEL 398

Query: 525 KKKALLF 531
           KKKA LF
Sbjct: 399 KKKASLF 405



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 74/259 (28%), Positives = 108/259 (41%), Gaps = 19/259 (7%)

Query: 270 EDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPD 329
           E   K+  TS  S+     SS  GSPS ++ AK+  ++L Y+DLAA+PK KAI DI+RPD
Sbjct: 2   ERLQKQPLTSPGSVSPSRDSSVPGSPSSIV-AKMDNQVLGYKDLAAIPKDKAILDIERPD 60

Query: 330 MISYSPYISHSAGDRQSYGES-PQLLSPTPTEGDQDDRSYKQCRTSSPSSTGSVSLGRYT 388
           ++ Y P+ ++S  +      S  + LSP  T        +   R  SP      S  R T
Sbjct: 61  LMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWADSR--SPGIISQASAPRTT 118

Query: 389 PTSR-SPQHYSRPAARRSDGEDGSLDQDNRKKSSWLMLKGDADTRTNSPDLDTQSLSHSS 447
            T R S  H+  P   R D          +++ S   + G   T+    DL  +S    +
Sbjct: 119 GTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRES---VGGSPQTKHLIEDLIIESSKFPA 175

Query: 448 GTDRDPLQRMAGDSFHSQYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFG 507
               DP Q        + Y   P    +V    R        + +  R  + EE +E   
Sbjct: 176 AQPPDPNQPA---KIETDYWPCPPSLAVVETEWR--------KRKASRRGAEEEEEEEDD 224

Query: 508 MSIEEFDRLALWKRNDLKK 526
            S EE   L   +R +L K
Sbjct: 225 DSGEEMKALRERQREELSK 243


>gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Homo
           sapiens]
          Length = 358

 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 45/65 (69%), Positives = 52/65 (80%)

Query: 467 KIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKK 526
           +IYPY+ L+VTN+ R KLP  VDR RLERHLS E+F  VF MS EEF +LALWKRN+LKK
Sbjct: 294 QIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKK 353

Query: 527 KALLF 531
           KA LF
Sbjct: 354 KASLF 358



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 64/232 (27%), Positives = 95/232 (40%), Gaps = 18/232 (7%)

Query: 297 RVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGES-PQLLS 355
           R+  AK+  ++L Y+DLAA+PK KAI DI+RPD++ Y P+ ++S  +      S  + LS
Sbjct: 3   RLQKAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRERSLS 62

Query: 356 PTPTEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSR-SPQHYSRPAARRSDGEDGSLDQ 414
           P  T        +   R  SP      S  R T T R S  H+  P   R D        
Sbjct: 63  PKSTSPPPSPEVWADSR--SPGIISQASAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPP 120

Query: 415 DNRKKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSQYKIYPYDSL 474
             +++ S   + G   T+    DL  +S    +    DP Q        + Y   P    
Sbjct: 121 IYKQRES---VGGSPQTKHLIEDLIIESSKFPAAQPPDPNQPA---KIETDYWPCPPSLA 174

Query: 475 IVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKK 526
           +V    R        + +  R  + EE +E    S EE   L   +R +L K
Sbjct: 175 VVETEWR--------KRKASRRGAEEEEEEEDDDSGEEMKALRERQREELSK 218


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,484,124
Number of Sequences: 37866
Number of extensions: 1193719
Number of successful extensions: 5868
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 397
Number of HSP's that attempted gapping in prelim test: 3971
Number of HSP's gapped (non-prelim): 1454
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.