Guide to the Human Genome
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Search of human proteins with 194272196

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194272196 actin binding LIM protein family, member 2 isoform
1 [Homo sapiens]
         (645 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194272196 actin binding LIM protein family, member 2 isoform ...  1352   0.0  
gi|194272198 actin binding LIM protein family, member 2 isoform ...  1234   0.0  
gi|194272200 actin binding LIM protein family, member 2 isoform ...  1128   0.0  
gi|194272204 actin binding LIM protein family, member 2 isoform ...   934   0.0  
gi|194272207 actin binding LIM protein family, member 2 isoform ...   830   0.0  
gi|153792514 actin binding LIM protein family, member 2 isoform ...   828   0.0  
gi|194272202 actin binding LIM protein family, member 2 isoform ...   828   0.0  
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]      658   0.0  
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]      658   0.0  
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]      643   0.0  
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi...   601   e-172
gi|51173717 actin-binding LIM protein 1 isoform s [Homo sapiens]      242   9e-64
gi|166706883 erythrocyte membrane protein band 4.9 isoform 2 [Ho...   158   2e-38
gi|166706881 erythrocyte membrane protein band 4.9 isoform 2 [Ho...   158   2e-38
gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Ho...   154   2e-37
gi|166706879 erythrocyte membrane protein band 4.9 isoform 1 [Ho...   154   2e-37
gi|166706875 erythrocyte membrane protein band 4.9 isoform 1 [Ho...   154   2e-37
gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Ho...   147   4e-35
gi|170932518 paxillin isoform 3 [Homo sapiens]                        139   8e-33
gi|170932516 paxillin isoform 2 [Homo sapiens]                        139   8e-33
gi|170932514 paxillin isoform 1 [Homo sapiens]                        139   8e-33
gi|221316659 leupaxin isoform 1 [Homo sapiens]                        115   2e-25
gi|4758670 leupaxin isoform 2 [Homo sapiens]                          115   2e-25
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   111   2e-24
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   110   3e-24
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   110   3e-24
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   110   3e-24
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   109   9e-24
gi|109638745 transforming growth factor beta 1 induced transcrip...   108   1e-23
gi|21361591 transforming growth factor beta 1 induced transcript...   108   1e-23

>gi|194272196 actin binding LIM protein family, member 2 isoform 1
           [Homo sapiens]
          Length = 645

 Score = 1352 bits (3498), Expect = 0.0
 Identities = 645/645 (100%), Positives = 645/645 (100%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360

Query: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIPY 420
           RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIPY
Sbjct: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIPY 420

Query: 421 FRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD 480
           FRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD
Sbjct: 421 FRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD 480

Query: 481 GEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 540
           GEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR
Sbjct: 481 GEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 540

Query: 541 FPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPK 600
           FPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPK
Sbjct: 541 FPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPK 600

Query: 601 DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 601 DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645


>gi|194272198 actin binding LIM protein family, member 2 isoform 2
           [Homo sapiens]
          Length = 611

 Score = 1234 bits (3194), Expect = 0.0
 Identities = 600/645 (93%), Positives = 600/645 (93%), Gaps = 34/645 (5%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360

Query: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIPY 420
           RTSSPSSTGSVSLGRYTPTSRSPQHYSRP       T S   LS                
Sbjct: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPGSESGRSTPSLSVLS---------------- 404

Query: 421 FRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD 480
                            DSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD
Sbjct: 405 -----------------DSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD 447

Query: 481 GEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 540
           GEDGSLDQDNRK KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR
Sbjct: 448 GEDGSLDQDNRK-KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 506

Query: 541 FPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPK 600
           FPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPK
Sbjct: 507 FPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPK 566

Query: 601 DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 567 DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 611


>gi|194272200 actin binding LIM protein family, member 2 isoform 3
           [Homo sapiens]
          Length = 572

 Score = 1128 bits (2918), Expect = 0.0
 Identities = 560/645 (86%), Positives = 561/645 (86%), Gaps = 73/645 (11%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360

Query: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIPY 420
           RTSSPSSTGSVSLGRYTPTSRSPQHYSRP       T S   LS                
Sbjct: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPGSESGRSTPSLSVLS---------------- 404

Query: 421 FRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD 480
                            DSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD
Sbjct: 405 -----------------DSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD 447

Query: 481 GEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSR 540
           GEDGSLDQDNRK KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 
Sbjct: 448 GEDGSLDQDNRK-KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS- 505

Query: 541 FPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPK 600
                                                 +YKIYPYDSLIVTNRIRVKLPK
Sbjct: 506 --------------------------------------QYKIYPYDSLIVTNRIRVKLPK 527

Query: 601 DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 528 DVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 572


>gi|194272204 actin binding LIM protein family, member 2 isoform 5
           [Homo sapiens]
          Length = 531

 Score =  934 bits (2415), Expect = 0.0
 Identities = 489/646 (75%), Positives = 503/646 (77%), Gaps = 116/646 (17%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI        S+  GD+  +SY + 
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI--------SHSAGDR--QSYGES 350

Query: 361 -RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIP 419
            +  SP+ T      R     R+    S P+ T SV                        
Sbjct: 351 PQLLSPTPTEGDQDDRSYKQCRT----SSPSSTGSVSL---------------------- 384

Query: 420 YFRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRS 479
                  GR TP+               ++P+H+  P                  AARRS
Sbjct: 385 -------GRYTPT--------------SRSPQHYSRP------------------AARRS 405

Query: 480 DGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 539
           DGEDGSLDQDNRK KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS
Sbjct: 406 DGEDGSLDQDNRK-KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 464

Query: 540 RFPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLP 599
                                                  +YKIYPYDSLIVTNRIRVKLP
Sbjct: 465 ---------------------------------------QYKIYPYDSLIVTNRIRVKLP 485

Query: 600 KDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           KDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 486 KDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 531


>gi|194272207 actin binding LIM protein family, member 2 isoform 7
           [Homo sapiens]
          Length = 470

 Score =  830 bits (2144), Expect = 0.0
 Identities = 425/541 (78%), Positives = 438/541 (80%), Gaps = 76/541 (14%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI        S+  GD+  +SY + 
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYI--------SHSAGDR--QSYGES 350

Query: 361 -RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIP 419
            +  SP+ T      R     R+    S P+ T SV                        
Sbjct: 351 PQLLSPTPTEGDQDDRSYKQCRT----SSPSSTGSVSL---------------------- 384

Query: 420 YFRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRS 479
                  GR TP+               ++P+H+  P                  AARRS
Sbjct: 385 -------GRYTPT--------------SRSPQHYSRP------------------AARRS 405

Query: 480 DGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 539
           DGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS
Sbjct: 406 DGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHS 465

Query: 540 R 540
           R
Sbjct: 466 R 466


>gi|153792514 actin binding LIM protein family, member 2 isoform 6
           [Homo sapiens]
          Length = 521

 Score =  828 bits (2139), Expect = 0.0
 Identities = 394/411 (95%), Positives = 395/411 (96%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360

Query: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTS 411
           RTSSPSSTGSVSLGRYTPTSRSPQHYSRPA   S G    L        +S
Sbjct: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSLDQDNRKQKSS 411



 Score =  271 bits (694), Expect = 1e-72
 Identities = 216/589 (36%), Positives = 262/589 (44%), Gaps = 117/589 (19%)

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C +C    +GEV+    K +H  CFVC  C      G      G+      C+L      
Sbjct: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYI----CTLDYQ--- 76

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEA 202
                 G R C  C   I+ G+ + AL K +H  CF C  C             LP+   
Sbjct: 77  ---RLYGTR-CFSCDQFIE-GEVVSALGKTYHPDCFVCAVCR------------LPFPPG 119

Query: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPA 262
           D     G  C  C+K  +  V      H       C  CG     G+ +       WH  
Sbjct: 120 DRVTFNGKEC-MCQK-CSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKH-WHLG 176

Query: 263 CRQAARTEDRNKETRTSSESIISVPASSTSGSP--SRVIYAKLG-----------GEILD 309
           C +             S   +++    S  G P      +AK G           G +L+
Sbjct: 177 CFKCK-----------SCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLE 225

Query: 310 YRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTG 369
             +    P         +        Y+  S+    +  +  + +   K+ RTSS S   
Sbjct: 226 AGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIIS 285

Query: 370 SVSLGRYTPTSRSPQH--YSRPAGTV-------SVGTSSCLSLSQHPSPTSVFRHHYIPY 420
             +    + TS SP    Y++  G +       ++  S  +     P   S     Y PY
Sbjct: 286 VPA----SSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMIS-----YSPY 336

Query: 421 FRGSESGRSTPSLSVLSDSKPPPSTYQQ----APRHFHVPDTGVKDNIYRKPPIYRQHAA 476
              S   R +       +      +Y+Q    +P        G      R P  Y + AA
Sbjct: 337 ISHSAGDRQS-----YGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAA 391

Query: 477 RRSDGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDS 536
           RRSDGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDS
Sbjct: 392 RRSDGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDS 451

Query: 537 FHSRFPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRV 596
           FHS                                       +YKIYPYDSLIVTNRIRV
Sbjct: 452 FHS---------------------------------------QYKIYPYDSLIVTNRIRV 472

Query: 597 KLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           KLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 473 KLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 521


>gi|194272202 actin binding LIM protein family, member 2 isoform 4
           [Homo sapiens]
          Length = 559

 Score =  828 bits (2138), Expect = 0.0
 Identities = 393/401 (98%), Positives = 393/401 (98%)

Query: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60
           MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG
Sbjct: 1   MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEG 60

Query: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120
           GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD
Sbjct: 61  GFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGD 120

Query: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180
           RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
Sbjct: 121 RVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC 180

Query: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240
           KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR
Sbjct: 181 KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVR 240

Query: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300
           CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY
Sbjct: 241 CGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIY 300

Query: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360
           AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC
Sbjct: 301 AKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQC 360

Query: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCL 401
           RTSSPSSTGSVSLGRYTPTSRSPQHYSRPA   S G    L
Sbjct: 361 RTSSPSSTGSVSLGRYTPTSRSPQHYSRPAARRSDGEDGSL 401



 Score =  371 bits (953), Expect = e-102
 Identities = 255/589 (43%), Positives = 300/589 (50%), Gaps = 79/589 (13%)

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C +C    +GEV+    K +H  CFVC  C      G      G+      C+L      
Sbjct: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYI----CTLDYQ--- 76

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEA 202
                 G R C  C   I+ G+ + AL K +H  CF C  C             LP+   
Sbjct: 77  ---RLYGTR-CFSCDQFIE-GEVVSALGKTYHPDCFVCAVCR------------LPFPPG 119

Query: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPA 262
           D     G  C  C+K  +  V      H       C  CG     G+ +       WH  
Sbjct: 120 DRVTFNGKEC-MCQK-CSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKH-WHLG 176

Query: 263 CRQAARTEDRNKETRTSSESIISVPASSTSGSP--SRVIYAKLG-----------GEILD 309
           C +             S   +++    S  G P      +AK G           G +L+
Sbjct: 177 CFKCK-----------SCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLE 225

Query: 310 YRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTG 369
             +    P         +        Y+  S+    +  +  + +   K+ RTSS S   
Sbjct: 226 AGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIIS 285

Query: 370 SVSLGRYTPTSRSPQH--YSRPAGTV-------SVGTSSCLSLSQHPSPTSVFRHHYIPY 420
             +    + TS SP    Y++  G +       ++  S  +     P   S     Y PY
Sbjct: 286 VPA----SSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMIS-----YSPY 336

Query: 421 FRGSESGRSTPSLSVLSDSKPPPSTYQQ----APRHFHVPDTGVKDNIYRKPPIYRQHAA 476
              S   R +       +      +Y+Q    +P        G      R P  Y + AA
Sbjct: 337 ISHSAGDRQS-----YGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAA 391

Query: 477 RRSDGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDS 536
           RRSDGEDGSLDQDNRK KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDS
Sbjct: 392 RRSDGEDGSLDQDNRK-KSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDS 450

Query: 537 FHSRFPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRV 596
           FHSRFPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRV
Sbjct: 451 FHSRFPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRV 510

Query: 597 KLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           KLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF
Sbjct: 511 KLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 559


>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
          Length = 718

 Score =  658 bits (1697), Expect = 0.0
 Identities = 351/736 (47%), Positives = 444/736 (60%), Gaps = 133/736 (18%)

Query: 4   VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
           V+ PQ    P EK     I C+ CG  CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 22  VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 78

Query: 64  VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
           ++ GEY+CTLDYQR+YGTRC  C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 79  IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 138

Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
           FNG++C+CQ C+ P+S  SS   +    +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 139 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 196

Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
           GK+L  EYISKDG PYCE DY   FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 197 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 256

Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKL 303
           MF EGEEMYLQGS++WHP C+Q+ +TE++ + TRTSSESI S P SS  GSP   IYAK+
Sbjct: 257 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKV 316

Query: 304 GGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGD---RQSYG------------ 348
             EILDY+DLAA+PK KAIYDI+RPD+I+Y P+ +    D   RQS G            
Sbjct: 317 DNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSA 376

Query: 349 EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP-TSRSPQHYSRPAGTVSVGTSSCLSLSQ 405
           EG QD R     R++S  S  S    R  YTP TSRSPQH+ RP    S           
Sbjct: 377 EGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPS----------- 425

Query: 406 HPSPTSVFRHHYIPYFRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIY 465
                               SGR++P L    DS+P   TY QAP+HFHVPD G+  NIY
Sbjct: 426 --------------------SGRNSP-LPYRPDSRPLTPTYAQAPKHFHVPDQGI--NIY 462

Query: 466 RKPPIYRQHAARRSD---------------------GEDGSLDQDNRKQKSSWLMLKGDA 504
           RKPPIY+QHAA  +                       E   ++ D+     S+ ++  D 
Sbjct: 463 RKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDM 522

Query: 505 DTRTNSPDLDTQSLSHSSGTDRDPLQRMAGD----------------------------- 535
             R++  + D + L        + L ++                                
Sbjct: 523 KRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPI 582

Query: 536 SFHSRFPYSKSDPLPGHGKNGLDQR-NANLAPCGADPDASWGMREY-------------- 580
           +  S  P SK+  LPG+G+NGL +  + + A   +  D S G+R+Y              
Sbjct: 583 NSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMD 642

Query: 581 -----------KIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDR 629
                      KI+PY+ L+VTNR R K+ ++VDRTRLERHL+PE F+E+FGMSI+EFDR
Sbjct: 643 RGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDR 702

Query: 630 LALWKRNDLKKKALLF 645
           L LW+RND+KKKA LF
Sbjct: 703 LPLWRRNDMKKKAKLF 718


>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
          Length = 778

 Score =  658 bits (1697), Expect = 0.0
 Identities = 351/736 (47%), Positives = 444/736 (60%), Gaps = 133/736 (18%)

Query: 4   VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
           V+ PQ    P EK     I C+ CG  CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 82  VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 138

Query: 64  VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
           ++ GEY+CTLDYQR+YGTRC  C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 139 IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 198

Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
           FNG++C+CQ C+ P+S  SS   +    +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 199 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 256

Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
           GK+L  EYISKDG PYCE DY   FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 257 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 316

Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKL 303
           MF EGEEMYLQGS++WHP C+Q+ +TE++ + TRTSSESI S P SS  GSP   IYAK+
Sbjct: 317 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKV 376

Query: 304 GGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGD---RQSYG------------ 348
             EILDY+DLAA+PK KAIYDI+RPD+I+Y P+ +    D   RQS G            
Sbjct: 377 DNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSA 436

Query: 349 EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP-TSRSPQHYSRPAGTVSVGTSSCLSLSQ 405
           EG QD R     R++S  S  S    R  YTP TSRSPQH+ RP    S           
Sbjct: 437 EGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPS----------- 485

Query: 406 HPSPTSVFRHHYIPYFRGSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIY 465
                               SGR++P L    DS+P   TY QAP+HFHVPD G+  NIY
Sbjct: 486 --------------------SGRNSP-LPYRPDSRPLTPTYAQAPKHFHVPDQGI--NIY 522

Query: 466 RKPPIYRQHAARRSD---------------------GEDGSLDQDNRKQKSSWLMLKGDA 504
           RKPPIY+QHAA  +                       E   ++ D+     S+ ++  D 
Sbjct: 523 RKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDM 582

Query: 505 DTRTNSPDLDTQSLSHSSGTDRDPLQRMAGD----------------------------- 535
             R++  + D + L        + L ++                                
Sbjct: 583 KRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPI 642

Query: 536 SFHSRFPYSKSDPLPGHGKNGLDQR-NANLAPCGADPDASWGMREY-------------- 580
           +  S  P SK+  LPG+G+NGL +  + + A   +  D S G+R+Y              
Sbjct: 643 NSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMD 702

Query: 581 -----------KIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDR 629
                      KI+PY+ L+VTNR R K+ ++VDRTRLERHL+PE F+E+FGMSI+EFDR
Sbjct: 703 RGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDR 762

Query: 630 LALWKRNDLKKKALLF 645
           L LW+RND+KKKA LF
Sbjct: 763 LPLWRRNDMKKKAKLF 778


>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
          Length = 746

 Score =  643 bits (1658), Expect = 0.0
 Identities = 351/764 (45%), Positives = 444/764 (58%), Gaps = 161/764 (21%)

Query: 4   VSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFF 63
           V+ PQ    P EK     I C+ CG  CKGEVLRVQ K+FHIKCF CK CGCDLA+GGFF
Sbjct: 22  VAHPQDPHHPSEKP---VIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFF 78

Query: 64  VRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVT 123
           ++ GEY+CTLDYQR+YGTRC  C +F+EGEVV+ALGKTYHP+CF C +C+ PFPPGDRVT
Sbjct: 79  IKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVT 138

Query: 124 FNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC 183
           FNG++C+CQ C+ P+S  SS   +    +C GCG +IKNGQAL+ALDK WHLGCFKCKSC
Sbjct: 139 FNGRDCLCQLCAQPMS--SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC 196

Query: 184 GKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQ 243
           GK+L  EYISKDG PYCE DY   FG++C++C ++ITG+VLEAG+KHYHPSCA C RC Q
Sbjct: 197 GKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQ 256

Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNK----------------------------E 275
           MF EGEEMYLQGS++WHP C+Q+ +TE++ +                             
Sbjct: 257 MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFFYSKSLIRRTGRSPSLQP 316

Query: 276 TRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSP 335
           TRTSSESI S P SS  GSP   IYAK+  EILDY+DLAA+PK KAIYDI+RPD+I+Y P
Sbjct: 317 TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEP 376

Query: 336 YISHSAGD---RQSYG------------EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP 378
           + +    D   RQS G            EG QD R     R++S  S  S    R  YTP
Sbjct: 377 FYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTP 436

Query: 379 -TSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIPYFRGSESGRSTPSLSVLS 437
            TSRSPQH+ RP    S                               SGR++P L    
Sbjct: 437 TTSRSPQHFHRPGNEPS-------------------------------SGRNSP-LPYRP 464

Query: 438 DSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSD----------------- 480
           DS+P   TY QAP+HFHVPD G+  NIYRKPPIY+QHAA  +                  
Sbjct: 465 DSRPLTPTYAQAPKHFHVPDQGI--NIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQ 522

Query: 481 ----GEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGD- 535
                E   ++ D+     S+ ++  D   R++  + D + L        + L ++    
Sbjct: 523 APDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGL 582

Query: 536 ----------------------------SFHSRFPYSKSDPLPGHGKNGLDQR-NANLAP 566
                                       +  S  P SK+  LPG+G+NGL +  + + A 
Sbjct: 583 GQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQ 642

Query: 567 CGADPDASWGMREY-------------------------KIYPYDSLIVTNRIRVKLPKD 601
             +  D S G+R+Y                         KI+PY+ L+VTNR R K+ ++
Sbjct: 643 YNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRE 702

Query: 602 VDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           VDRTRLERHL+PE F+E+FGMSI+EFDRL LW+RND+KKKA LF
Sbjct: 703 VDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF 746


>gi|7662330 actin binding LIM protein family, member 3 [Homo
           sapiens]
          Length = 683

 Score =  601 bits (1549), Expect = e-172
 Identities = 334/704 (47%), Positives = 420/704 (59%), Gaps = 109/704 (15%)

Query: 16  KSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDY 75
           +  S  I C  CG+ CKGEV+RV + +FHI+CF C+ CGC LA+ GFF +  EYICT DY
Sbjct: 15  RGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDY 74

Query: 76  QRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCS 135
           Q+LYGTRC SC  FI GEV+SALG+TYHP CFVC++CR PFP GD+VTF+GKEC+CQ CS
Sbjct: 75  QQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCS 134

Query: 136 LPVSVGSSAHLS-QGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISK 194
              S+ SS  +  +G   C GC  EIK+GQ+L+ALDK WH+ CFKC++C  +L  EYISK
Sbjct: 135 Q--SMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGEYISK 192

Query: 195 DGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQ 254
           DG+PYCE+DYHA+FGI+C++C++YI+GRVLEAG KHYHP+CA CVRC QMF EGEEMYL 
Sbjct: 193 DGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLT 252

Query: 255 GSSIWHPACRQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLA 314
           GS +WHP C+QAAR E + K  RTS  SI   P  S+ GSP+RVI AK+  EIL+Y+DLA
Sbjct: 253 GSEVWHPICKQAARAEKKLKHRRTSETSI--SPPGSSIGSPNRVICAKVDNEILNYKDLA 310

Query: 315 ALPKSKAIYDIDRPDMISYSP---YISHSAGDRQSYGEG-------DQDDRSYKQCRTSS 364
           ALPK K+IY++ RPD+ISY P   Y+S    +R  YGE         QD       R   
Sbjct: 311 ALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDIYENLDLRQRR 370

Query: 365 PSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIPYFRGS 424
            SS G +    Y+    SP     P                         HHY  Y  G 
Sbjct: 371 ASSPGYIDSPTYSRQGMSPTFSRSP-------------------------HHY--YRSGP 403

Query: 425 ESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHA--------- 475
           ESGRS+P  S L      P++Y QAP+HFH+P      NIYRKPPIY++H          
Sbjct: 404 ESGRSSPYHSQLDVRSSTPTSY-QAPKHFHIP--AGDSNIYRKPPIYKRHGDLSTATKSK 460

Query: 476 --------------------------------------ARR--SDGEDGSLDQDNRKQKS 495
                                                 ARR  S GE+   D+   K +S
Sbjct: 461 TSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQS 520

Query: 496 --SWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFP----------- 542
               L+LK +   R++S   D  +   SS + R+ L     +   +  P           
Sbjct: 521 GIGRLILKEEMKARSSS-YADPWTPPRSSTSSREALHTAGYEMSLNGSPRSHYLADSDPL 579

Query: 543 YSKSDPLPGHGKNGLDQR-NANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPKD 601
            SKS  LP + +NGL +  +A+L    +    +WGMREYKIYPY+ L+VT R R +LPKD
Sbjct: 580 ISKSASLPAYRRNGLHRTPSADLFHYDSMNAVNWGMREYKIYPYELLLVTTRGRNRLPKD 639

Query: 602 VDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           VDRTRLERHLS EEF +VFGM+I EFDRLALWKRN+LKK+A LF
Sbjct: 640 VDRTRLERHLSQEEFYQVFGMTISEFDRLALWKRNELKKQARLF 683


>gi|51173717 actin-binding LIM protein 1 isoform s [Homo sapiens]
          Length = 455

 Score =  242 bits (617), Expect = 9e-64
 Identities = 178/483 (36%), Positives = 245/483 (50%), Gaps = 109/483 (22%)

Query: 244 MFAEGEEMYLQGSSIWHPACRQAARTEDRNK----------------------------E 275
           MF EGEEMYLQGS++WHP C+Q+ +TE++ +                             
Sbjct: 1   MFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFFYSKSLIRRTGRSPSLQP 60

Query: 276 TRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSP 335
           TRTSSESI S P SS  GSP   IYAK+  EILDY+DLAA+PK KAIYDI+RPD+I+Y P
Sbjct: 61  TRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEP 120

Query: 336 YISHSAGD---RQSYG------------EGDQDDRSYKQCRTSSPSSTGSVSLGR--YTP 378
           + +    D   RQS G            EG QD R     R++S  S  S    R  YTP
Sbjct: 121 FYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTP 180

Query: 379 -TSRSPQHYSRPAGTVSVGTSSCLSLSQHPSPTSVFRHHYIPYFRGSESGRSTPSLSVLS 437
            TSRSPQH+ RP   +++          +  P  +++ H       + + +S  S  ++ 
Sbjct: 181 TTSRSPQHFHRPDQGINI----------YRKP-PIYKQH------AALAAQSKSSEDIIK 223

Query: 438 DSKPPPSTYQQAPRHFHVPDTGVKDNIYRKPP---IYRQHAARRSDG---EDGSLDQDNR 491
            SK P +   QAP     P   ++ + +  PP   +      RRS G   +D  L +  +
Sbjct: 224 FSKFPAA---QAPDPSETPK--IETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQ 278

Query: 492 KQKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDS---FHSRFPYSKSDP 548
            Q+   + L           +++ +S   SS      L     DS     S  P SK+  
Sbjct: 279 LQEEQLMKLNSGLGQLILKEEMEKESRERSS------LLASRYDSPINSASHIPSSKTAS 332

Query: 549 LPGHGKNGLDQR-NANLAPCGADPDASWGMREY-------------------------KI 582
           LPG+G+NGL +  + + A   +  D S G+R+Y                         KI
Sbjct: 333 LPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKI 392

Query: 583 YPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKA 642
           +PY+ L+VTNR R K+ ++VDRTRLERHL+PE F+E+FGMSI+EFDRL LW+RND+KKKA
Sbjct: 393 FPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKA 452

Query: 643 LLF 645
            LF
Sbjct: 453 KLF 455


>gi|166706883 erythrocyte membrane protein band 4.9 isoform 2 [Homo
           sapiens]
          Length = 383

 Score =  158 bits (399), Expect = 2e-38
 Identities = 130/402 (32%), Positives = 190/402 (47%), Gaps = 46/402 (11%)

Query: 270 EDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPD 329
           E   K+  TS  S+     SS  GSPS ++ AK+  ++L Y+DLAA+PK KAI DI+RPD
Sbjct: 2   ERLQKQPLTSPGSVSPSRDSSVPGSPSSIV-AKMDNQVLGYKDLAAIPKDKAILDIERPD 60

Query: 330 MISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP 389
           ++ Y P+ ++S  +        +        R+ SP ST           SRSP   S+ 
Sbjct: 61  LMIYEPHFTYSLLEHVELPRSRE--------RSLSPKSTSPPPSPEVWADSRSPGIISQA 112

Query: 390 AGTVSVGTS-SCLSLSQHPSPTSVFRHHYI--PYFRGSESGRSTPSLS------VLSDSK 440
           +   + GT  + L    HP  +    + Y   P ++  ES   +P         ++  SK
Sbjct: 113 SAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSK 172

Query: 441 ----PPPSTYQQAPRHFHV----PDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRK 492
                PP   Q A          P   V +  +RK     + A+RR   E+   + D+  
Sbjct: 173 FPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRK-----RKASRRGAEEEEEEEDDDSG 227

Query: 493 QKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFPY--------S 544
           ++   L  +   +    + +L    L         P++R    S   R P+        S
Sbjct: 228 EEMKALRERQREELSKVTSNLGKMILKEEMEKSL-PIRRKTR-SLPDRTPFHTSLHQGTS 285

Query: 545 KSDPLPGHGKNGLDQ-RNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPKDVD 603
           KS  LP +G+  L + ++   +P G++     G    +IYPY+ L+VTN+ R KLP  VD
Sbjct: 286 KSSSLPAYGRTTLSRLQSTEFSPSGSET----GSPGLQIYPYEMLVVTNKGRTKLPPGVD 341

Query: 604 RTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           R RLERHLS E+F  VF MS EEF +LALWKRN+LKKKA LF
Sbjct: 342 RMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 383


>gi|166706881 erythrocyte membrane protein band 4.9 isoform 2 [Homo
           sapiens]
          Length = 383

 Score =  158 bits (399), Expect = 2e-38
 Identities = 130/402 (32%), Positives = 190/402 (47%), Gaps = 46/402 (11%)

Query: 270 EDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPD 329
           E   K+  TS  S+     SS  GSPS ++ AK+  ++L Y+DLAA+PK KAI DI+RPD
Sbjct: 2   ERLQKQPLTSPGSVSPSRDSSVPGSPSSIV-AKMDNQVLGYKDLAAIPKDKAILDIERPD 60

Query: 330 MISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP 389
           ++ Y P+ ++S  +        +        R+ SP ST           SRSP   S+ 
Sbjct: 61  LMIYEPHFTYSLLEHVELPRSRE--------RSLSPKSTSPPPSPEVWADSRSPGIISQA 112

Query: 390 AGTVSVGTS-SCLSLSQHPSPTSVFRHHYI--PYFRGSESGRSTPSLS------VLSDSK 440
           +   + GT  + L    HP  +    + Y   P ++  ES   +P         ++  SK
Sbjct: 113 SAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSK 172

Query: 441 ----PPPSTYQQAPRHFHV----PDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRK 492
                PP   Q A          P   V +  +RK     + A+RR   E+   + D+  
Sbjct: 173 FPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRK-----RKASRRGAEEEEEEEDDDSG 227

Query: 493 QKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFPY--------S 544
           ++   L  +   +    + +L    L         P++R    S   R P+        S
Sbjct: 228 EEMKALRERQREELSKVTSNLGKMILKEEMEKSL-PIRRKTR-SLPDRTPFHTSLHQGTS 285

Query: 545 KSDPLPGHGKNGLDQ-RNANLAPCGADPDASWGMREYKIYPYDSLIVTNRIRVKLPKDVD 603
           KS  LP +G+  L + ++   +P G++     G    +IYPY+ L+VTN+ R KLP  VD
Sbjct: 286 KSSSLPAYGRTTLSRLQSTEFSPSGSET----GSPGLQIYPYEMLVVTNKGRTKLPPGVD 341

Query: 604 RTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           R RLERHLS E+F  VF MS EEF +LALWKRN+LKKKA LF
Sbjct: 342 RMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 383


>gi|166706877 erythrocyte membrane protein band 4.9 isoform 1 [Homo
           sapiens]
          Length = 405

 Score =  154 bits (390), Expect = 2e-37
 Identities = 133/420 (31%), Positives = 193/420 (45%), Gaps = 60/420 (14%)

Query: 270 EDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPD 329
           E   K+  TS  S+     SS  GSPS ++ AK+  ++L Y+DLAA+PK KAI DI+RPD
Sbjct: 2   ERLQKQPLTSPGSVSPSRDSSVPGSPSSIV-AKMDNQVLGYKDLAAIPKDKAILDIERPD 60

Query: 330 MISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP 389
           ++ Y P+ ++S  +        +        R+ SP ST           SRSP   S+ 
Sbjct: 61  LMIYEPHFTYSLLEHVELPRSRE--------RSLSPKSTSPPPSPEVWADSRSPGIISQA 112

Query: 390 AGTVSVGTS-SCLSLSQHPSPTSVFRHHYI--PYFRGSESGRSTPSLS------VLSDSK 440
           +   + GT  + L    HP  +    + Y   P ++  ES   +P         ++  SK
Sbjct: 113 SAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSK 172

Query: 441 ----PPPSTYQQAPRHFHV----PDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRK 492
                PP   Q A          P   V +  +RK     + A+RR   E+   + D+  
Sbjct: 173 FPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRK-----RKASRRGAEEEEEEEDDDSG 227

Query: 493 QKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFPY--------S 544
           ++   L  +   +    + +L    L         P++R    S   R P+        S
Sbjct: 228 EEMKALRERQREELSKVTSNLGKMILKEEMEKSL-PIRRKTR-SLPDRTPFHTSLHQGTS 285

Query: 545 KSDPLPGHGKNGLDQ-RNANLAPCGADPDASW-----GMR-------------EYKIYPY 585
           KS  LP +G+  L + ++   +P G++  +       G R             E KIYPY
Sbjct: 286 KSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPY 345

Query: 586 DSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           + L+VTN+ R KLP  VDR RLERHLS E+F  VF MS EEF +LALWKRN+LKKKA LF
Sbjct: 346 EMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 405


>gi|166706879 erythrocyte membrane protein band 4.9 isoform 1 [Homo
           sapiens]
          Length = 405

 Score =  154 bits (390), Expect = 2e-37
 Identities = 133/420 (31%), Positives = 193/420 (45%), Gaps = 60/420 (14%)

Query: 270 EDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPD 329
           E   K+  TS  S+     SS  GSPS ++ AK+  ++L Y+DLAA+PK KAI DI+RPD
Sbjct: 2   ERLQKQPLTSPGSVSPSRDSSVPGSPSSIV-AKMDNQVLGYKDLAAIPKDKAILDIERPD 60

Query: 330 MISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP 389
           ++ Y P+ ++S  +        +        R+ SP ST           SRSP   S+ 
Sbjct: 61  LMIYEPHFTYSLLEHVELPRSRE--------RSLSPKSTSPPPSPEVWADSRSPGIISQA 112

Query: 390 AGTVSVGTS-SCLSLSQHPSPTSVFRHHYI--PYFRGSESGRSTPSLS------VLSDSK 440
           +   + GT  + L    HP  +    + Y   P ++  ES   +P         ++  SK
Sbjct: 113 SAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSK 172

Query: 441 ----PPPSTYQQAPRHFHV----PDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRK 492
                PP   Q A          P   V +  +RK     + A+RR   E+   + D+  
Sbjct: 173 FPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRK-----RKASRRGAEEEEEEEDDDSG 227

Query: 493 QKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFPY--------S 544
           ++   L  +   +    + +L    L         P++R    S   R P+        S
Sbjct: 228 EEMKALRERQREELSKVTSNLGKMILKEEMEKSL-PIRRKTR-SLPDRTPFHTSLHQGTS 285

Query: 545 KSDPLPGHGKNGLDQ-RNANLAPCGADPDASW-----GMR-------------EYKIYPY 585
           KS  LP +G+  L + ++   +P G++  +       G R             E KIYPY
Sbjct: 286 KSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPY 345

Query: 586 DSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           + L+VTN+ R KLP  VDR RLERHLS E+F  VF MS EEF +LALWKRN+LKKKA LF
Sbjct: 346 EMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 405


>gi|166706875 erythrocyte membrane protein band 4.9 isoform 1 [Homo
           sapiens]
          Length = 405

 Score =  154 bits (390), Expect = 2e-37
 Identities = 133/420 (31%), Positives = 193/420 (45%), Gaps = 60/420 (14%)

Query: 270 EDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPD 329
           E   K+  TS  S+     SS  GSPS ++ AK+  ++L Y+DLAA+PK KAI DI+RPD
Sbjct: 2   ERLQKQPLTSPGSVSPSRDSSVPGSPSSIV-AKMDNQVLGYKDLAAIPKDKAILDIERPD 60

Query: 330 MISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRP 389
           ++ Y P+ ++S  +        +        R+ SP ST           SRSP   S+ 
Sbjct: 61  LMIYEPHFTYSLLEHVELPRSRE--------RSLSPKSTSPPPSPEVWADSRSPGIISQA 112

Query: 390 AGTVSVGTS-SCLSLSQHPSPTSVFRHHYI--PYFRGSESGRSTPSLS------VLSDSK 440
           +   + GT  + L    HP  +    + Y   P ++  ES   +P         ++  SK
Sbjct: 113 SAPRTTGTPRTSLPHFHHPETSRPDSNIYKKPPIYKQRESVGGSPQTKHLIEDLIIESSK 172

Query: 441 ----PPPSTYQQAPRHFHV----PDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRK 492
                PP   Q A          P   V +  +RK     + A+RR   E+   + D+  
Sbjct: 173 FPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRK-----RKASRRGAEEEEEEEDDDSG 227

Query: 493 QKSSWLMLKGDADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFPY--------S 544
           ++   L  +   +    + +L    L         P++R    S   R P+        S
Sbjct: 228 EEMKALRERQREELSKVTSNLGKMILKEEMEKSL-PIRRKTR-SLPDRTPFHTSLHQGTS 285

Query: 545 KSDPLPGHGKNGLDQ-RNANLAPCGADPDASW-----GMR-------------EYKIYPY 585
           KS  LP +G+  L + ++   +P G++  +       G R             E KIYPY
Sbjct: 286 KSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPY 345

Query: 586 DSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF 645
           + L+VTN+ R KLP  VDR RLERHLS E+F  VF MS EEF +LALWKRN+LKKKA LF
Sbjct: 346 EMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF 405


>gi|166706885 erythrocyte membrane protein band 4.9 isoform 3 [Homo
           sapiens]
          Length = 358

 Score =  147 bits (370), Expect = 4e-35
 Identities = 120/375 (32%), Positives = 177/375 (47%), Gaps = 45/375 (12%)

Query: 297 RVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRS 356
           R+  AK+  ++L Y+DLAA+PK KAI DI+RPD++ Y P+ ++S  +        +    
Sbjct: 3   RLQKAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRE---- 58

Query: 357 YKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPAGTVSVGTS-SCLSLSQHPSPTSVFRH 415
               R+ SP ST           SRSP   S+ +   + GT  + L    HP  +    +
Sbjct: 59  ----RSLSPKSTSPPPSPEVWADSRSPGIISQASAPRTTGTPRTSLPHFHHPETSRPDSN 114

Query: 416 HYI--PYFRGSESGRSTPSLS------VLSDSK----PPPSTYQQAPRHFHV----PDTG 459
            Y   P ++  ES   +P         ++  SK     PP   Q A          P   
Sbjct: 115 IYKKPPIYKQRESVGGSPQTKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLA 174

Query: 460 VKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRKQKSSWLMLKGDADTRTNSPDLDTQSLS 519
           V +  +RK     + A+RR   E+   + D+  ++   L  +   +    + +L    L 
Sbjct: 175 VVETEWRK-----RKASRRGAEEEEEEEDDDSGEEMKALRERQREELSKVTSNLGKMILK 229

Query: 520 HSSGTDRDPLQRMAGDSFHSRFPY--------SKSDPLPGHGKNGLDQ-RNANLAPCGAD 570
                   P++R    S   R P+        SKS  LP +G+  L + ++   +P G++
Sbjct: 230 EEMEKSL-PIRRKTR-SLPDRTPFHTSLHQGTSKSSSLPAYGRTTLSRLQSTEFSPSGSE 287

Query: 571 PDASWGMREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRL 630
                G    +IYPY+ L+VTN+ R KLP  VDR RLERHLS E+F  VF MS EEF +L
Sbjct: 288 T----GSPGLQIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKL 343

Query: 631 ALWKRNDLKKKALLF 645
           ALWKRN+LKKKA LF
Sbjct: 344 ALWKRNELKKKASLF 358


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  139 bits (350), Expect = 8e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 299

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 300 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 358 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 404



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  139 bits (350), Expect = 8e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 432

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 433 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 491 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 537



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  139 bits (350), Expect = 8e-33
 Identities = 76/227 (33%), Positives = 107/227 (47%), Gaps = 13/227 (5%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C     G+V+    K +H + FVC  C  ++    FF R G+  C  DY  L+  R
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C+ C+  I  +VV+AL +T+HP+ F CA C   F P      +GK   C+K         
Sbjct: 417 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGK-AYCRK--------- 466

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCE 201
             +       CGGC   I     + AL+  WH  CF C+ C    +N  +   DG PYCE
Sbjct: 467 -DYFDMFAPKCGGCARAILENY-ISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 524

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
             YH + G  C  C+K ITGR + A  K +HP   +C  C +   +G
Sbjct: 525 VHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKG 571



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 16/57 (28%), Positives = 25/57 (43%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ C     G  +    K FH + FVC  C   L +G F  +  +  C   + +L+
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score =  115 bits (287), Expect = 2e-25
 Identities = 68/226 (30%), Positives = 99/226 (43%), Gaps = 13/226 (5%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C +C     G+V+    + +H + FVC  C  ++    FF R G   C  DY +L+  RC
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
             C   I  +V++A+ +T+HP+ F C+ C   F         G E   +K   P      
Sbjct: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC--RK 265

Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEA 202
             L+     CGGC   +     L A+D  WH  CF C  C        +   DG P+CE 
Sbjct: 266 DFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCEL 324

Query: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
            YH + G  C  C + ITGR + A    +HP   +C  C    ++G
Sbjct: 325 HYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 370



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C SC + I G+V+ ALG+++HP+ FVC  C+            G     ++  L      
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 207

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYCE 201
              L      C  C   I + + L A+++ WH   F C  CG++  AE +  KD  PYC 
Sbjct: 208 YHQLFSP--RCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCR 264

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQG 255
            D+ A F  +C  C + +    L A +  +HP C +C  C   F+ G    L G
Sbjct: 265 KDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 318



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 40/111 (36%), Positives = 47/111 (42%), Gaps = 1/111 (0%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C  C        L   D  +H +CFVC  C    + G FF   G   C L Y    GT C
Sbjct: 275 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLC 334

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
             C Q I G  +SA+G  +HP+ FVCA C      G     N K   CQ C
Sbjct: 335 HGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDK-TYCQPC 384



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 16/57 (28%), Positives = 26/57 (45%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ CG    G  +      FH + FVC  C   L++G F  +  +  C   + +L+
Sbjct: 333 LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score =  115 bits (287), Expect = 2e-25
 Identities = 68/226 (30%), Positives = 99/226 (43%), Gaps = 13/226 (5%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C +C     G+V+    + +H + FVC  C  ++    FF R G   C  DY +L+  RC
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 211

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
             C   I  +V++A+ +T+HP+ F C+ C   F         G E   +K   P      
Sbjct: 212 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC--RK 260

Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEA 202
             L+     CGGC   +     L A+D  WH  CF C  C        +   DG P+CE 
Sbjct: 261 DFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCEL 319

Query: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248
            YH + G  C  C + ITGR + A    +HP   +C  C    ++G
Sbjct: 320 HYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 365



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C SC + I G+V+ ALG+++HP+ FVC  C+            G     ++  L      
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 202

Query: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYCE 201
              L      C  C   I + + L A+++ WH   F C  CG++  AE +  KD  PYC 
Sbjct: 203 YHQLFSP--RCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCR 259

Query: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQG 255
            D+ A F  +C  C + +    L A +  +HP C +C  C   F+ G    L G
Sbjct: 260 KDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 313



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 40/111 (36%), Positives = 47/111 (42%), Gaps = 1/111 (0%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C  C        L   D  +H +CFVC  C    + G FF   G   C L Y    GT C
Sbjct: 270 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLC 329

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
             C Q I G  +SA+G  +HP+ FVCA C      G     N K   CQ C
Sbjct: 330 HGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDK-TYCQPC 379



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 16/57 (28%), Positives = 26/57 (45%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79
           LC+ CG    G  +      FH + FVC  C   L++G F  +  +  C   + +L+
Sbjct: 328 LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  111 bits (277), Expect = 2e-24
 Identities = 83/295 (28%), Positives = 116/295 (39%), Gaps = 61/295 (20%)

Query: 6   QPQAAPSPLEKSPSTAILCNTCGNVCKGE------VLRVQDKYFHIKCFVCKACGCDLAE 59
           Q + +P P   + S A+    C   C+        ++    + +H  CFVC  C     E
Sbjct: 18  QHRQSPPPATGNMSDALANAVCQR-CQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPE 76

Query: 60  GGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVC------- 112
           G F+  +G   C  D+Q L+   C SC +FI G V+ A+   +HP CF C +C       
Sbjct: 77  GLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADL 136

Query: 113 --------RLPFPPGDRVTFNG-KECMCQKCSL-----PVSVGSSA-------------- 144
                    L  P  +R    G  + +CQ+C L     P+   S A              
Sbjct: 137 GFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKE 196

Query: 145 -----------------HLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-L 186
                            H   G+  CG C   I+ G+ + AL K WH+  F C  C K  
Sbjct: 197 LTAEARELKGELYCLPCHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPF 255

Query: 187 LNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
           L   +  K GL YCE  Y+  FG  C +C   I G V+ A  K +  SC  C  C
Sbjct: 256 LGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 310



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 32/112 (28%), Positives = 54/112 (48%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C    +G V+    K +H++ FVC  C         + ++G   C   Y +L+G  
Sbjct: 221 ICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDV 280

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
           C++C   IEG+VVSAL K +   CF C+ C       ++      + +C++C
Sbjct: 281 CYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRC 332



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 173 WHLGCFKCKSCGKLL-NAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHY 231
           +H  CF C  C +      +   +G  YCE D+   F   C SC ++I GRV++A   ++
Sbjct: 60  YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNW 119

Query: 232 HPSCALCVRCGQMFAE 247
           HP C  C  C    A+
Sbjct: 120 HPGCFRCELCDVELAD 135


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  110 bits (276), Expect = 3e-24
 Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
           C +CG    G V++  +  +H  CF C+ C  +LA+ GF    G ++C   + R     L
Sbjct: 98  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157

Query: 79  YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
               C  C   I+ + +      YHPD F C  C      G  +T   +E   +   LP 
Sbjct: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 210

Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
                 H   G+  CG C   I+ G+ + AL K WH+  F C  C K  L   +  K GL
Sbjct: 211 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 264

Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
            YCE  Y+  FG  C +C   I G V+ A  K +  SC  C  C
Sbjct: 265 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 308



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C  V   + L  +   +H   F C  CG +L      ++ GE  C   + ++    
Sbjct: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 219

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C +C + IEG VV+ALGK +H + FVCA C  PF  G R         C+          
Sbjct: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 268

Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
             H +Q     C  C + +  G  + AL+K W + CF C +C     L  +++  D  P 
Sbjct: 269 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 326

Query: 200 CEADY 204
           C+  Y
Sbjct: 327 CKRCY 331



 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)

Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
           VC  C+  F P +R+  +  E       +C +C  P   G            H  Q L +
Sbjct: 36  VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 95

Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
             CG CG E   G+ + A++ +WH GCF+C+ C  +L +  ++   G   C   ++ +  
Sbjct: 96  PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154

Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
                  C  C   I  + L      YHP    C  CG ++ AE  E+
Sbjct: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 202


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  110 bits (276), Expect = 3e-24
 Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
           C +CG    G V++  +  +H  CF C+ C  +LA+ GF    G ++C   + R     L
Sbjct: 71  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 130

Query: 79  YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
               C  C   I+ + +      YHPD F C  C      G  +T   +E   +   LP 
Sbjct: 131 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 183

Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
                 H   G+  CG C   I+ G+ + AL K WH+  F C  C K  L   +  K GL
Sbjct: 184 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 237

Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
            YCE  Y+  FG  C +C   I G V+ A  K +  SC  C  C
Sbjct: 238 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 281



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C  V   + L  +   +H   F C  CG +L      ++ GE  C   + ++    
Sbjct: 134 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 192

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C +C + IEG VV+ALGK +H + FVCA C  PF  G R         C+          
Sbjct: 193 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 241

Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
             H +Q     C  C + +  G  + AL+K W + CF C +C     L  +++  D  P 
Sbjct: 242 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 299

Query: 200 CEADY 204
           C+  Y
Sbjct: 300 CKRCY 304



 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)

Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
           VC  C+  F P +R+  +  E       +C +C  P   G            H  Q L +
Sbjct: 9   VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 68

Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
             CG CG E   G+ + A++ +WH GCF+C+ C  +L +  ++   G   C   ++ +  
Sbjct: 69  PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 127

Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
                  C  C   I  + L      YHP    C  CG ++ AE  E+
Sbjct: 128 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 175


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  110 bits (276), Expect = 3e-24
 Identities = 70/224 (31%), Positives = 97/224 (43%), Gaps = 19/224 (8%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQR-----L 78
           C +CG    G V++  +  +H  CF C+ C  +LA+ GF    G ++C   + R     L
Sbjct: 76  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 135

Query: 79  YGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPV 138
               C  C   I+ + +      YHPD F C  C      G  +T   +E   +   LP 
Sbjct: 136 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHC------GKELTAEARELKGELYCLP- 188

Query: 139 SVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGL 197
                 H   G+  CG C   I+ G+ + AL K WH+  F C  C K  L   +  K GL
Sbjct: 189 -----CHDKMGVPICGACRRPIE-GRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGL 242

Query: 198 PYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
            YCE  Y+  FG  C +C   I G V+ A  K +  SC  C  C
Sbjct: 243 AYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTC 286



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 17/185 (9%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C  V   + L  +   +H   F C  CG +L      ++ GE  C   + ++    
Sbjct: 139 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPI 197

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142
           C +C + IEG VV+ALGK +H + FVCA C  PF  G R         C+          
Sbjct: 198 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPF-LGHRHYEKKGLAYCE---------- 246

Query: 143 SAHLSQGLRS-CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK--LLNAEYISKDGLPY 199
             H +Q     C  C + +  G  + AL+K W + CF C +C     L  +++  D  P 
Sbjct: 247 -THYNQLFGDVCYNC-SHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPV 304

Query: 200 CEADY 204
           C+  Y
Sbjct: 305 CKRCY 309



 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 25/168 (14%)

Query: 108 VCAVCRLPFPPGDRVTFNGKEC------MCQKCSLPVSVG---------SSAHLSQGLRS 152
           VC  C+  F P +R+  +  E       +C +C  P   G            H  Q L +
Sbjct: 14  VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 73

Query: 153 --CGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYHAKFG 209
             CG CG E   G+ + A++ +WH GCF+C+ C  +L +  ++   G   C   ++ +  
Sbjct: 74  PCCGSCG-EFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 132

Query: 210 -----IRCDSCEKYITGRVLEAGEKHYHPSCALCVRCG-QMFAEGEEM 251
                  C  C   I  + L      YHP    C  CG ++ AE  E+
Sbjct: 133 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAREL 180


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  109 bits (272), Expect = 9e-24
 Identities = 76/282 (26%), Positives = 114/282 (40%), Gaps = 61/282 (21%)

Query: 19  STAILCNTCGNVCKG------EVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICT 72
           + A+   TC   CKG      +++    + +H +CFVC  C     EG F+  +G   C 
Sbjct: 2   ANALASATCER-CKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60

Query: 73  LDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCR---------------LPFP 117
            D+Q L+   C  C +FI G V+ A+  ++HP+CF C +C+               L  P
Sbjct: 61  HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120

Query: 118 PGDRVTFNG-KECMCQKCSLPV--------------------SVGSS------------- 143
             +R    G  + +CQKC   +                    + G               
Sbjct: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180

Query: 144 ---AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPY 199
               H   G+  CG C   I+ G+ + A+ K WH+  F C  C K  L   +  + GL Y
Sbjct: 181 CLPCHDKMGVPICGACRRPIE-GRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAY 239

Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRC 241
           CE  Y+  FG  C  C + I G V+ A  K +  +C  C  C
Sbjct: 240 CETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTC 281



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 35/112 (31%), Positives = 56/112 (50%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           +C  C    +G V+    K +H++ FVC  C         + R+G   C   Y +L+G  
Sbjct: 192 ICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDV 251

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134
           CF C++ IEG+VVSAL K +  +CF C+ C       ++      + +C+KC
Sbjct: 252 CFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKC 303



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 173 WHLGCFKCKSCGKLL-NAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHY 231
           +H  CF C  C +      +   +G  YCE D+   F   C  C ++I GRV++A    +
Sbjct: 31  YHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSW 90

Query: 232 HPSCALCVRCGQMFAE 247
           HP C  C  C ++ A+
Sbjct: 91  HPECFRCDLCQEVLAD 106


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  108 bits (271), Expect = 1e-23
 Identities = 70/242 (28%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           LC +C     G+V+    + +H + FVC  C   L    FF + G   C   Y   +  R
Sbjct: 227 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 286

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKE--CMCQKCSLPVSV 140
           C  C+Q I  ++V+ALG  +HP+ F C  C  PF  GD   F+ +E    C++  L +  
Sbjct: 287 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHEREGRPYCRRDFLQLFA 343

Query: 141 GSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPY 199
                       C GC   I +   + AL   WH  CF C+ C        +   +G P 
Sbjct: 344 ----------PRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 392

Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
           CE  +HA+ G  C +C   +TGR + A  + +HP    C  C +   +G      G    
Sbjct: 393 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 452

Query: 260 HP 261
            P
Sbjct: 453 QP 454



 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 53/187 (28%), Positives = 83/187 (44%), Gaps = 13/187 (6%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C  C    + +++     ++H + F C +CG    + GF  R+G   C  D+ +L+  RC
Sbjct: 287 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 346

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
             C   I    +SAL   +HPDCFVC  C  PF  G      G+  +C+         + 
Sbjct: 347 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRP-LCE---------NH 396

Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCEA 202
            H  +G   C  CG  +  G+ + AL + +H   F C  C + L    +  + G PYC+ 
Sbjct: 397 FHARRG-SLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 454

Query: 203 DYHAKFG 209
            +   FG
Sbjct: 455 CFLKLFG 461



 Score = 36.6 bits (83), Expect = 0.074
 Identities = 19/58 (32%), Positives = 26/58 (44%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYG 80
           LC TCG    G  +    + FH   F C  C   L +G F  R G+  C   + +L+G
Sbjct: 404 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 461


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  108 bits (271), Expect = 1e-23
 Identities = 70/242 (28%), Positives = 103/242 (42%), Gaps = 17/242 (7%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTR 82
           LC +C     G+V+    + +H + FVC  C   L    FF + G   C   Y   +  R
Sbjct: 210 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269

Query: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKE--CMCQKCSLPVSV 140
           C  C+Q I  ++V+ALG  +HP+ F C  C  PF  GD   F+ +E    C++  L +  
Sbjct: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPF--GDE-GFHEREGRPYCRRDFLQLFA 326

Query: 141 GSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPY 199
                       C GC   I +   + AL   WH  CF C+ C        +   +G P 
Sbjct: 327 ----------PRCQGCQGPILDNY-ISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPL 375

Query: 200 CEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIW 259
           CE  +HA+ G  C +C   +TGR + A  + +HP    C  C +   +G      G    
Sbjct: 376 CENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYC 435

Query: 260 HP 261
            P
Sbjct: 436 QP 437



 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 53/187 (28%), Positives = 83/187 (44%), Gaps = 13/187 (6%)

Query: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83
           C  C    + +++     ++H + F C +CG    + GF  R+G   C  D+ +L+  RC
Sbjct: 270 CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRC 329

Query: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143
             C   I    +SAL   +HPDCFVC  C  PF  G      G+  +C+         + 
Sbjct: 330 QGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRP-LCE---------NH 379

Query: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGK-LLNAEYISKDGLPYCEA 202
            H  +G   C  CG  +  G+ + AL + +H   F C  C + L    +  + G PYC+ 
Sbjct: 380 FHARRG-SLCATCGLPV-TGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQP 437

Query: 203 DYHAKFG 209
            +   FG
Sbjct: 438 CFLKLFG 444



 Score = 36.6 bits (83), Expect = 0.074
 Identities = 19/58 (32%), Positives = 26/58 (44%)

Query: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYG 80
           LC TCG    G  +    + FH   F C  C   L +G F  R G+  C   + +L+G
Sbjct: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,356,096
Number of Sequences: 37866
Number of extensions: 1522904
Number of successful extensions: 6735
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 394
Number of HSP's that attempted gapping in prelim test: 4780
Number of HSP's gapped (non-prelim): 1492
length of query: 645
length of database: 18,247,518
effective HSP length: 109
effective length of query: 536
effective length of database: 14,120,124
effective search space: 7568386464
effective search space used: 7568386464
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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