Guide to the Human Genome
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Name: SHC1 Sequence: fasta or formatted (583aa) NCBI GI: 194239662
Description:

SHC (Src homology 2 domain containing) transforming protein 1 isoform 1

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [584aa] SHC (Src homology 2 domain containing) transforming protein 1 iso...
alt prot [473aa] SHC (Src homology 2 domain containing) transforming protein 1 iso...
alt prot [474aa] SHC (Src homology 2 domain containing) transforming protein 1 iso...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.4         43           2
 C cysteine            1.5          9           1
 D aspartate           5.3         31           2
 E glutamate           6.2         36           5
 F phenylalanine       2.7         16           2
 G glycine             9.9         58           4
 H histidine           2.4         14           2
 I isoleucine          2.6         15           2
 K lysine              3.6         21           1
 L leucine             9.8         57           3
 M methionine          2.7         16           1
 N asparagine          3.6         21           1
 P proline            11.5         67           5
 Q glutamine           4.1         24           2
 R arginine            6.5         38           3
 S serine              7.5         44           2
 T threonine           4.1         24           3
 V valine              5.8         34           2
 W tryptophan          0.7          4           1
 Y tyrosine            1.9         11           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SHC (Src homology 2 domain containing) transforming... 
SHC1                  0.996   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.809   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.805   SHC (Src homology 2 domain containing) transforming ...
SHC2                  0.408   SHC (Src homology 2 domain containing) transforming...
SHC3                  0.404   src homology 2 domain-containing transforming prote...
SHC4                  0.381   rai-like protein 
LOC100291393          0.118   PREDICTED: hypothetical protein XP_002347924 
FER                   0.036   fer (fps/fes related) tyrosine kinase 
SH2D3A                0.033   SH2 domain containing 3A 
SH2B1                 0.032   SH2B adaptor protein 1 isoform 2 
SH2B1                 0.032   SH2B adaptor protein 1 isoform 3 
SH2B1                 0.032   SH2B adaptor protein 1 isoform 2 
SH2B1                 0.032   SH2B adaptor protein 1 isoform 1 
SH2B1                 0.032   SH2B adaptor protein 1 isoform 2 
GULP1                 0.031   GULP, engulfment adaptor PTB domain containing 1 [Hom...
FES                   0.030   feline sarcoma oncogene isoform 2 
FES                   0.030   feline sarcoma oncogene isoform 1 
SH2D3C                0.030   SH2 domain containing 3C isoform a 
BCAR3                 0.030   breast cancer antiestrogen resistance 3 
SH2B3                 0.029   SH2B adaptor protein 3 
SH2B2                 0.028   SH2B adaptor protein 2 
SH2D3C                0.027   SH2 domain containing 3C isoform b 
SH2D3C                0.027   SH2 domain containing 3C isoform e 
SH2D3C                0.027   SH2 domain containing 3C isoform d 
SHD                   0.026   Src homology 2 domain containing transforming prote...
PLCG2                 0.024   phospholipase C, gamma 2 
NCK1                  0.024   NCK adaptor protein 1 
ABL2                  0.024   arg tyrosine kinase isoform c 
ABL2                  0.024   arg tyrosine kinase isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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