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Search of human proteins with 194018441
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194018441 potassium channel tetramerisation domain
containing 15 isoform 2 [Homo sapiens]
(283 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194018443 potassium channel tetramerisation domain containing... 575 e-164
gi|194018441 potassium channel tetramerisation domain containing... 575 e-164
gi|194018439 potassium channel tetramerisation domain containing... 471 e-133
gi|218505694 potassium channel tetramerisation domain containing... 427 e-120
gi|209969708 potassium channel tetramerisation domain containing... 425 e-119
gi|40217617 potassium channel tetramerisation domain containing ... 425 e-119
gi|189571693 potassium channel tetramerisation domain containing... 112 4e-25
gi|189571691 potassium channel tetramerisation domain containing... 112 4e-25
gi|71143104 potassium channel tetramerisation domain containing ... 106 2e-23
gi|146198864 potassium channel tetramerisation domain containing... 92 4e-19
gi|19923973 potassium channel tetramerisation domain containing ... 79 6e-15
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens] 76 4e-14
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens] 76 4e-14
gi|38198663 potassium channel tetramerisation domain containing ... 74 1e-13
gi|23308551 potassium channel tetramerisation domain containing ... 70 3e-12
gi|55926200 potassium channel tetramerisation domain containing ... 69 6e-12
gi|142356950 potassium channel tetramerisation domain containing... 65 5e-11
gi|155369221 potassium channel tetramerisation domain containing... 65 7e-11
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens] 63 3e-10
gi|30578412 potassium channel tetramerisation domain containing ... 60 2e-09
gi|13994353 potassium channel tetramerisation domain containing ... 59 4e-09
gi|51036594 potassium channel tetramerisation domain containing ... 59 5e-09
gi|169234778 potassium channel tetramerisation domain containing... 56 3e-08
gi|46255026 potassium channel tetramerisation domain containing ... 55 7e-08
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo... 55 9e-08
gi|53829365 potassium channel tetramerisation domain containing ... 54 2e-07
gi|45387953 potassium channel tetramerization domain containing ... 52 5e-07
gi|39753959 potassium channel tetramerisation domain containing ... 51 1e-06
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 50 2e-06
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 50 3e-06
>gi|194018443 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 575 bits (1481), Expect = e-164
Identities = 283/283 (100%), Positives = 283/283 (100%)
Query: 1 MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI 60
MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI
Sbjct: 1 MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI 60
Query: 61 DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS 120
DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS
Sbjct: 61 DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS 120
Query: 121 KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER 180
KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER
Sbjct: 121 KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER 180
Query: 181 IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRG 240
IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRG
Sbjct: 181 IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRG 240
Query: 241 FSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD 283
FSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD
Sbjct: 241 FSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD 283
>gi|194018441 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 575 bits (1481), Expect = e-164
Identities = 283/283 (100%), Positives = 283/283 (100%)
Query: 1 MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI 60
MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI
Sbjct: 1 MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI 60
Query: 61 DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS 120
DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS
Sbjct: 61 DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS 120
Query: 121 KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER 180
KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER
Sbjct: 121 KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER 180
Query: 181 IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRG 240
IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRG
Sbjct: 181 IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRG 240
Query: 241 FSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD 283
FSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD
Sbjct: 241 FSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD 283
>gi|194018439 potassium channel tetramerisation domain containing 15
isoform 1 [Homo sapiens]
Length = 234
Score = 471 bits (1212), Expect = e-133
Identities = 231/231 (100%), Positives = 231/231 (100%)
Query: 1 MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI 60
MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI
Sbjct: 1 MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI 60
Query: 61 DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS 120
DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS
Sbjct: 61 DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS 120
Query: 121 KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER 180
KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER
Sbjct: 121 KLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGER 180
Query: 181 IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQ 231
IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQ
Sbjct: 181 IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQ 231
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 427 bits (1099), Expect = e-120
Identities = 206/258 (79%), Positives = 229/258 (88%)
Query: 26 NMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRL 85
NMSR +TRSP SPL QGIP PAQLTKSNAPVHIDVGGHMYTSSLATLTKYP+SRI RL
Sbjct: 608 NMSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRL 667
Query: 86 FNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQP 145
F+GTEPIVLDSLKQHYFIDRDG++FRY+L+FLRTSKLL+PDDFKD++LLYEEA+Y+QLQP
Sbjct: 668 FDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQP 727
Query: 146 MVRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSV 205
M+ E+ERW+Q++E R SR C+CLVVRV PDLGERI LSG+K+LIEEVFPE GDVMCNSV
Sbjct: 728 MLLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSV 787
Query: 206 NAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRGFSVAASCGGGVDSSQFSEYVLCREE 265
NAGWN D THVIRFPLNGYC LNSVQVLERL QRGF + SCGGGVDSSQFSEYVL RE
Sbjct: 788 NAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRREL 847
Query: 266 RRPQPTPTAVRIKQEPLD 283
RR P+ +RIKQEPLD
Sbjct: 848 RRTPRVPSVIRIKQEPLD 865
>gi|209969708 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 425 bits (1093), Expect = e-119
Identities = 205/257 (79%), Positives = 228/257 (88%)
Query: 27 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86
MSR +TRSP SPL QGIP PAQLTKSNAPVHIDVGGHMYTSSLATLTKYP+SRI RLF
Sbjct: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
Query: 87 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146
+GTEPIVLDSLKQHYFIDRDG++FRY+L+FLRTSKLL+PDDFKD++LLYEEA+Y+QLQPM
Sbjct: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
Query: 147 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN 206
+ E+ERW+Q++E R SR C+CLVVRV PDLGERI LSG+K+LIEEVFPE GDVMCNSVN
Sbjct: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
Query: 207 AGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRGFSVAASCGGGVDSSQFSEYVLCREER 266
AGWN D THVIRFPLNGYC LNSVQVLERL QRGF + SCGGGVDSSQFSEYVL RE R
Sbjct: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
Query: 267 RPQPTPTAVRIKQEPLD 283
R P+ +RIKQEPLD
Sbjct: 241 RTPRVPSVIRIKQEPLD 257
>gi|40217617 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 425 bits (1093), Expect = e-119
Identities = 205/257 (79%), Positives = 228/257 (88%)
Query: 27 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86
MSR +TRSP SPL QGIP PAQLTKSNAPVHIDVGGHMYTSSLATLTKYP+SRI RLF
Sbjct: 1 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60
Query: 87 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146
+GTEPIVLDSLKQHYFIDRDG++FRY+L+FLRTSKLL+PDDFKD++LLYEEA+Y+QLQPM
Sbjct: 61 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM 120
Query: 147 VRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVN 206
+ E+ERW+Q++E R SR C+CLVVRV PDLGERI LSG+K+LIEEVFPE GDVMCNSVN
Sbjct: 121 LLEMERWKQDRETGRFSRPCECLVVRVAPDLGERITLSGDKSLIEEVFPEIGDVMCNSVN 180
Query: 207 AGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRGFSVAASCGGGVDSSQFSEYVLCREER 266
AGWN D THVIRFPLNGYC LNSVQVLERL QRGF + SCGGGVDSSQFSEYVL RE R
Sbjct: 181 AGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSSQFSEYVLRRELR 240
Query: 267 RPQPTPTAVRIKQEPLD 283
R P+ +RIKQEPLD
Sbjct: 241 RTPRVPSVIRIKQEPLD 257
>gi|189571693 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 112 bits (280), Expect = 4e-25
Identities = 52/92 (56%), Positives = 72/92 (78%), Gaps = 1/92 (1%)
Query: 57 PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116
PV ++VGGH+YT+SL TLT+YPDS + +F G P D + +YFIDRDG +FRYVL+F
Sbjct: 13 PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
Query: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVR 148
LRTS+L LP DFK+F LL +EA +YQ++P+++
Sbjct: 72 LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQ 103
>gi|189571691 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 112 bits (280), Expect = 4e-25
Identities = 52/92 (56%), Positives = 72/92 (78%), Gaps = 1/92 (1%)
Query: 57 PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116
PV ++VGGH+YT+SL TLT+YPDS + +F G P D + +YFIDRDG +FRYVL+F
Sbjct: 13 PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
Query: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVR 148
LRTS+L LP DFK+F LL +EA +YQ++P+++
Sbjct: 72 LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQ 103
>gi|71143104 potassium channel tetramerisation domain containing 21
[Homo sapiens]
Length = 260
Score = 106 bits (265), Expect = 2e-23
Identities = 50/107 (46%), Positives = 77/107 (71%), Gaps = 1/107 (0%)
Query: 57 PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116
P+ ++VGG +YT+SLATLT +PDS + +F+G P DS + + FIDRDG++FRY+L+F
Sbjct: 4 PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNF 62
Query: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRS 163
LRTS L LP+DF++ LL EA +YQ+QP++ L+ + E + ++
Sbjct: 63 LRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKN 109
>gi|146198864 potassium channel tetramerisation domain containing 4
[Homo sapiens]
Length = 259
Score = 92.4 bits (228), Expect = 4e-19
Identities = 45/99 (45%), Positives = 70/99 (70%), Gaps = 2/99 (2%)
Query: 60 IDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRT 119
++VGG++Y + TLTKYPD+ + + NG D+ HYFIDRDG +FR+VL+FLR
Sbjct: 37 LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRN 95
Query: 120 SKLLLPDDFKDFSLLYEEARYYQLQPMVRELE-RWQQEQ 157
+LLLP+ F++ LL +EA ++QL+ + E++ RW++EQ
Sbjct: 96 GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQ 134
>gi|19923973 potassium channel tetramerisation domain containing 12
[Homo sapiens]
Length = 325
Score = 78.6 bits (192), Expect = 6e-15
Identities = 42/100 (42%), Positives = 62/100 (62%), Gaps = 3/100 (3%)
Query: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEP--IVLDSLKQHYFIDRDGEIFRYVLS 115
V ++VGG +Y + T+ PDS + R+F +P + DS K +F+DRDG +FRY+L
Sbjct: 36 VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS-KGRFFLDRDGFLFRYILD 94
Query: 116 FLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ 155
+LR +L+LPD F + S L EA Y++L +VR L QQ
Sbjct: 95 YLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQ 134
>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
Length = 229
Score = 75.9 bits (185), Expect = 4e-14
Identities = 34/90 (37%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Query: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117
V ++VGG ++T+ +T+ ++P SR++R+ +G + + F+DRDG++F ++L FL
Sbjct: 7 VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
Query: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMV 147
RT +LLLP +F D+ L EA +Y+L+ +V
Sbjct: 66 RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
Length = 272
Score = 75.9 bits (185), Expect = 4e-14
Identities = 34/90 (37%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Query: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117
V ++VGG ++T+ +T+ ++P SR++R+ +G + + F+DRDG++F ++L FL
Sbjct: 7 VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
Query: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMV 147
RT +LLLP +F D+ L EA +Y+L+ +V
Sbjct: 66 RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
>gi|38198663 potassium channel tetramerisation domain containing 8
[Homo sapiens]
Length = 473
Score = 74.3 bits (181), Expect = 1e-13
Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 12/188 (6%)
Query: 12 SLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSL 71
+L GS G+ +S + SP + AA P P + V ++VGG +Y +
Sbjct: 2 ALKDTGSGGSTILPISEMVSSSSSPGASAAAA--PGPCAPSPFPEVVELNVGGQVYVTKH 59
Query: 72 ATLTKYPDSRISRLFNGTEP---------IVLDSLKQHYFIDRDGEIFRYVLSFLRTSKL 122
+TL PDS ++ +F+ + P + DS + +FIDRDG +FRYVL +LR +L
Sbjct: 60 STLLSVPDSTLASMFSPSSPRGGARRRGELPRDS-RARFFIDRDGFLFRYVLDYLRDKQL 118
Query: 123 LLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDLGERIA 182
LP+ F + L EA Y+QL +V+ L +Q L V+ + +
Sbjct: 119 ALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALL 178
Query: 183 LSGEKALI 190
L G A +
Sbjct: 179 LRGAAAAV 186
>gi|23308551 potassium channel tetramerisation domain containing 7
[Homo sapiens]
Length = 289
Score = 69.7 bits (169), Expect = 3e-12
Identities = 45/128 (35%), Positives = 73/128 (57%), Gaps = 5/128 (3%)
Query: 36 PVSPLAAQ-GIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVL 94
P +P A Q G LP + V +++GG +T+ L+TL Y D+ ++ +F+G I
Sbjct: 30 PATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPT 89
Query: 95 DSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQ 154
DS + YFIDRDG F VL+FLR+ L + + +Y+EA+YY + P++ +LE Q
Sbjct: 90 DS-EGRYFIDRDGTHFGDVLNFLRSGDLPPRERVR---AVYKEAQYYAIGPLLEQLENMQ 145
Query: 155 QEQEQRRR 162
+ ++ R
Sbjct: 146 PLKGEKVR 153
>gi|55926200 potassium channel tetramerisation domain containing 16
[Homo sapiens]
Length = 428
Score = 68.6 bits (166), Expect = 6e-12
Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQ---HYFIDRDGEIFRYVL 114
V ++VGG +Y + +TL P S + ++F+ D K +FIDRDG +FRY+L
Sbjct: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
Query: 115 SFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL 150
+LR +++LPD F + L EA Y+QL +V+ L
Sbjct: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
>gi|142356950 potassium channel tetramerisation domain containing 14
[Homo sapiens]
Length = 255
Score = 65.5 bits (158), Expect = 5e-11
Identities = 39/120 (32%), Positives = 69/120 (57%), Gaps = 9/120 (7%)
Query: 46 PLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDR 105
P P + T S V ++VGG +T++L TL K+P S+++ +F+ D+ + +FIDR
Sbjct: 24 PRPRRPTMSTV-VELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDA-EGRFFIDR 81
Query: 106 DGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ---EQEQRRR 162
FR +L +LRT ++ + +Y EA++Y+++P+V+ LE Q EQ R++
Sbjct: 82 PSTYFRPILDYLRTGQV----PTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQ 137
>gi|155369221 potassium channel tetramerisation domain containing 19
[Homo sapiens]
Length = 926
Score = 65.1 bits (157), Expect = 7e-11
Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 11/107 (10%)
Query: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117
+ + VG H Y ++L TL KYP+ L + + + + Q I DG++FR++L+FL
Sbjct: 398 IKVYVGSHWYATTLQTLLKYPE-----LLSNPQRVYWITYGQTLLIHGDGQMFRHILNFL 452
Query: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL------ERWQQEQE 158
R KL LP +FK++ L +E Y + + L + W QE+E
Sbjct: 453 RLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQCEAYKSWTQEKE 499
Score = 55.5 bits (132), Expect = 5e-08
Identities = 34/103 (33%), Positives = 57/103 (55%), Gaps = 5/103 (4%)
Query: 59 HIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLR 118
H +VGG ++ + L+++PDS + + + + S Q FIDRDG FR+V +L
Sbjct: 16 HFNVGGWHFSVPRSKLSQFPDSLLWKEASA----LTSSESQRLFIDRDGSTFRHVHYYLY 71
Query: 119 TSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRR 161
TSKL + +LLYE+A QL P+++ L+ ++ + R
Sbjct: 72 TSKLSF-SSCAELNLLYEQALGLQLMPLLQTLDNLKEGKHHLR 113
Score = 40.0 bits (92), Expect = 0.002
Identities = 17/44 (38%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Query: 110 FRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERW 153
FR++++FLR+ K+LLPD+F + +L E ++ P + E RW
Sbjct: 211 FRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEI-PALTEAVRW 253
Score = 31.6 bits (70), Expect = 0.82
Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 5/65 (7%)
Query: 66 MYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLP 125
+YT +L L KYPDS + +L LD +I +G +F++V ++L T +L L
Sbjct: 286 LYTMALGLLVKYPDSALGQL---RIESTLDG--SRLYITGNGVLFQHVKNWLGTCRLPLT 340
Query: 126 DDFKD 130
+ +
Sbjct: 341 ETISE 345
>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
Length = 707
Score = 62.8 bits (151), Expect = 3e-10
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 14/115 (12%)
Query: 41 AAQGIPLPAQLTKSNAP----VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDS 96
AA+G+P S P +H++VGG +++S TLT PDS S L +G + D
Sbjct: 7 AAEGVP-------SRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDE 59
Query: 97 LKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELE 151
FIDRD +F +L+FLRT K L P SLL+ EA++Y L P+VR L+
Sbjct: 60 TGA-IFIDRDPTVFAPILNFLRT-KELDPRGVHGSSLLH-EAQFYGLTPLVRRLQ 111
>gi|30578412 potassium channel tetramerisation domain containing 13
[Homo sapiens]
Length = 329
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/142 (29%), Positives = 78/142 (54%), Gaps = 6/142 (4%)
Query: 51 LTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIF 110
LT ++ V ++VGG ++ ++L TLT D+ + +F+G ++ D+ IDR G F
Sbjct: 36 LTPNSKYVKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDA-GGWVLIDRSGRHF 93
Query: 111 RYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLV 170
+L++LR + LP+ ++ L EARYY +Q ++ E Q +Q+R + + CL+
Sbjct: 94 GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLI---EDCQLALQQKRETLSPLCLI 150
Query: 171 VRVT-PDLGERIALSGEKALIE 191
VT P +++ S K +++
Sbjct: 151 PMVTSPREEQQLLASTSKPVVK 172
>gi|13994353 potassium channel tetramerisation domain containing 10
[Homo sapiens]
Length = 313
Score = 59.3 bits (142), Expect = 4e-09
Identities = 42/132 (31%), Positives = 72/132 (54%), Gaps = 3/132 (2%)
Query: 27 MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86
MS S+ S V P AA + S+ V ++VGG +Y +++ TLTK D+ + +F
Sbjct: 4 MSGESVVSSAV-PAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMF 61
Query: 87 NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146
+G ++ DS + IDR G+ F +L++LR + LP+ ++ L EA+YY +Q +
Sbjct: 62 SGRMEVLTDS-EGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL 120
Query: 147 VRELERWQQEQE 158
V E + Q ++
Sbjct: 121 VEECQAALQNKD 132
>gi|51036594 potassium channel tetramerisation domain containing 11
[Homo sapiens]
Length = 232
Score = 58.9 bits (141), Expect = 5e-09
Identities = 29/58 (50%), Positives = 42/58 (72%), Gaps = 3/58 (5%)
Query: 100 HYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM---VRELERWQ 154
HYFIDRDG+ FR++L+FLR +L LP + + +LL EA +YQ++P+ +RELE Q
Sbjct: 23 HYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDALRELEASQ 80
>gi|169234778 potassium channel tetramerisation domain containing 17
[Homo sapiens]
Length = 297
Score = 56.2 bits (134), Expect = 3e-08
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 19/152 (12%)
Query: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117
V ++VGG ++ ++ TL + S +SRL G E Y IDRD F +L+FL
Sbjct: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
Query: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDL 177
R KL+L D + +L EEA +Y + P++R ++ +E+ D V +V P
Sbjct: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKDRMEEK---------DYTVTQVPPKH 142
Query: 178 GERIALSGEKALIEEVFPETGDVMCNSVNAGW 209
R+ E+ L + M ++++ GW
Sbjct: 143 VYRVLQCQEEELTQ---------MVSTMSDGW 165
>gi|46255026 potassium channel tetramerisation domain containing 3
[Homo sapiens]
Length = 815
Score = 55.1 bits (131), Expect = 7e-08
Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 3/103 (2%)
Query: 48 PAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDG 107
PA S V ++VGG +++S TL PDS S L +G + D FIDRD
Sbjct: 10 PAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGA-IFIDRDP 68
Query: 108 EIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL 150
F +L+FLRT +L L ++L EA +Y + P+VR L
Sbjct: 69 AAFAPILNFLRTKELDLRG--VSINVLRHEAEFYGITPLVRRL 109
>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
sapiens]
Length = 316
Score = 54.7 bits (130), Expect = 9e-08
Identities = 35/140 (25%), Positives = 76/140 (54%), Gaps = 4/140 (2%)
Query: 55 NAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVL 114
N V ++VGG +Y +++ LT++ D+ + +F+G ++ D + IDR G+ F +L
Sbjct: 27 NKYVQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDK-EGWILIDRCGKHFGTIL 84
Query: 115 SFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVT 174
++LR + LP + ++ L EA+YY +Q +V + Q+++ + C+ ++
Sbjct: 85 NYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQP-VCNIPIITSL 143
Query: 175 PDLGERIALSGEKALIEEVF 194
+ ER+ S K +++ ++
Sbjct: 144 KE-EERLIESSTKPVVKLLY 162
>gi|53829365 potassium channel tetramerisation domain containing 2
[Homo sapiens]
Length = 263
Score = 53.5 bits (127), Expect = 2e-07
Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 21/172 (12%)
Query: 8 PSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPL--------AAQGIPL------PAQLTK 53
P+ + L G +G +GG R + P P AA PL P +
Sbjct: 8 PAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGG 67
Query: 54 SNAP--VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGE 108
A V ++VGG + ++ TL + P S + RL +P LDS K Y IDRD
Sbjct: 68 GGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP-ELDSDKDETGAYLIDRDPT 126
Query: 109 IFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQR 160
F +L++LR KL++ + + +L EEA +Y + +VR ++ ++ E R
Sbjct: 127 YFGPILNYLRHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKERIRDNENR 177
>gi|45387953 potassium channel tetramerization domain containing 18
[Homo sapiens]
Length = 426
Score = 52.4 bits (124), Expect = 5e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 2/84 (2%)
Query: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117
+ ++VGG +YT+ +L ++ DS ++ +F+G P+ D IDRDG +F+Y+L +L
Sbjct: 14 LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDE-SGACVIDRDGRLFKYLLDYL 72
Query: 118 RTSKLLLPDDFKDFSLLYEEARYY 141
++ +P D + L EEA Y+
Sbjct: 73 H-GEVQIPTDEQTRIALQEEADYF 95
>gi|39753959 potassium channel tetramerisation domain containing 9
[Homo sapiens]
Length = 389
Score = 50.8 bits (120), Expect = 1e-06
Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 17/148 (11%)
Query: 18 STGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAP----------VHIDVGGHMY 67
S +GG + ++L R +G P T S P + ++VGG +
Sbjct: 41 SVYNGKGGLIDDIALIRDDDVLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYF 100
Query: 68 TSSLATLT-KYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGEIFRYVLSFLRTSKLL 123
T++ +TL K PDS ++ +F + V + + H + IDR E F +L++LR +L+
Sbjct: 101 TTTRSTLVNKEPDSMLAHMFK--DKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLI 158
Query: 124 LPDDFKDFSLLYEEARYYQLQPMVRELE 151
+ D +L EEAR++ + ++ LE
Sbjct: 159 VNDGINLLGVL-EEARFFGIDSLIEHLE 185
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 50.4 bits (119), Expect = 2e-06
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Query: 39 PLAAQGIPLPAQLTKS---NAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLD 95
P+A+ +P P + + +A + ++V G + + TL +YPD+ + +
Sbjct: 21 PVASGPMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLG---SSERDFFYH 77
Query: 96 SLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ 155
Q YF DRD +IFR++L+F RT KL P + S EE ++ L P + + +
Sbjct: 78 PETQQYFFDRDPDIFRHILNFYRTGKLHYP-RHECISAYDEELAFFGLIPEIIG-DCCYE 135
Query: 156 EQEQRRRSRA 165
E + RRR A
Sbjct: 136 EYKDRRRENA 145
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 49.7 bits (117), Expect = 3e-06
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 8/110 (7%)
Query: 39 PLAAQGIPLPA---QLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLD 95
PLA Q +P PA + ++ + + ++V G + + TL +YPD+ + + + D
Sbjct: 21 PLAQQPLP-PAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLG---SSEKEFFYD 76
Query: 96 SLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQP 145
+ YF DRD ++FR+VL+F RT +L P + EE +Y L P
Sbjct: 77 ADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQ-ECIQAFDEELAFYGLVP 125
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,651,334
Number of Sequences: 37866
Number of extensions: 522137
Number of successful extensions: 1915
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1812
Number of HSP's gapped (non-prelim): 107
length of query: 283
length of database: 18,247,518
effective HSP length: 101
effective length of query: 182
effective length of database: 14,423,052
effective search space: 2624995464
effective search space used: 2624995464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.