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Search of human proteins with 193083108
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193083108 poly(rC) binding protein 2 isoform d [Homo
sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 720 0.0
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 716 0.0
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 707 0.0
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 703 0.0
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 633 0.0
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 620 e-178
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 588 e-168
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 569 e-162
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 479 e-135
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 405 e-113
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 345 5e-95
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 345 5e-95
gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens] 261 9e-70
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 155 5e-38
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 154 9e-38
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 154 9e-38
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 105 5e-23
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 102 7e-22
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 86 5e-17
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 80 2e-15
gi|17402900 far upstream element-binding protein [Homo sapiens] 75 1e-13
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 75 1e-13
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 74 2e-13
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 74 2e-13
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 70 2e-12
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 70 2e-12
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 70 2e-12
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 55 1e-07
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 55 1e-07
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 55 1e-07
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 720 bits (1859), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG 300
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG
Sbjct: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG 300
Query: 301 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 360
CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG
Sbjct: 301 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 360
Query: 361 GMGSS 365
GMGSS
Sbjct: 361 GMGSS 365
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 716 bits (1847), Expect = 0.0
Identities = 365/366 (99%), Positives = 365/366 (99%), Gaps = 1/366 (0%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Query: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLI 299
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW GLDASAQTTSHELTIPNDLI
Sbjct: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 300
Query: 300 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 359
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 301 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 360
Query: 360 GGMGSS 365
GGMGSS
Sbjct: 361 GGMGSS 366
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 707 bits (1826), Expect = 0.0
Identities = 361/365 (98%), Positives = 361/365 (98%), Gaps = 4/365 (1%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ
Sbjct: 177 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 236
Query: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG 300
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG
Sbjct: 237 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG 296
Query: 301 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 360
CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG
Sbjct: 297 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 356
Query: 361 GMGSS 365
GMGSS
Sbjct: 357 GMGSS 361
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 703 bits (1814), Expect = 0.0
Identities = 361/366 (98%), Positives = 361/366 (98%), Gaps = 5/366 (1%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ
Sbjct: 177 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 236
Query: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLI 299
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW GLDASAQTTSHELTIPNDLI
Sbjct: 237 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 296
Query: 300 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 359
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 297 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 356
Query: 360 GGMGSS 365
GGMGSS
Sbjct: 357 GGMGSS 362
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 633 bits (1633), Expect = 0.0
Identities = 334/366 (91%), Positives = 334/366 (91%), Gaps = 32/366 (8%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
PYRPKPSSSPVIFAGGQ AYTIQGQYAIPQ
Sbjct: 181 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 209
Query: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLI 299
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW GLDASAQTTSHELTIPNDLI
Sbjct: 210 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 269
Query: 300 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 359
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 270 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 329
Query: 360 GGMGSS 365
GGMGSS
Sbjct: 330 GGMGSS 335
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 620 bits (1600), Expect = e-178
Identities = 330/366 (90%), Positives = 330/366 (90%), Gaps = 36/366 (9%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
PYRPKPSSSPVIFAGGQ AYTIQGQYAIPQ
Sbjct: 177 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 205
Query: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDLI 299
PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW GLDASAQTTSHELTIPNDLI
Sbjct: 206 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLI 265
Query: 300 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 359
GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET
Sbjct: 266 GCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSET 325
Query: 360 GGMGSS 365
GGMGSS
Sbjct: 326 GGMGSS 331
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 588 bits (1517), Expect = e-168
Identities = 317/365 (86%), Positives = 317/365 (86%), Gaps = 47/365 (12%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT
Sbjct: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI
Sbjct: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE SPPKGVTI
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLE----SPPKGVTI 176
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
PYRPKPSSSPVIFAGGQ AYTIQGQYAIPQ
Sbjct: 177 PYRPKPSSSPVIFAGGQ-------------------------------AYTIQGQYAIPQ 205
Query: 241 PDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIG 300
PDLTKLHQLAMQQSHFPMTHGNTGFS GLDASAQTTSHELTIPNDLIG
Sbjct: 206 PDLTKLHQLAMQQSHFPMTHGNTGFSA------------GLDASAQTTSHELTIPNDLIG 253
Query: 301 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 360
CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG
Sbjct: 254 CIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETG 313
Query: 361 GMGSS 365
GMGSS
Sbjct: 314 GMGSS 318
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 569 bits (1467), Expect = e-162
Identities = 303/367 (82%), Positives = 325/367 (88%), Gaps = 13/367 (3%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
MD GV E GLNVTLTIRLLMHGKEVGSIIGKKGESVK++REESGARINISEGNCPERIIT
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCPERIIT 60
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
L GPTNAIFKAFAMIIDKLEEDI+SSMTNSTAASRPPVTLRLVVPA+QCGSLIGKGGCKI
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP-KGVT 179
KEIRESTGAQVQVAGDMLPNSTERAITIAG+PQS+ ECVKQIC+VMLETLSQSP + +T
Sbjct: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRVMT 180
Query: 180 IPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIP 239
IPY+P P+SSPVI AGGQDR SD+A +PH T DLEGPPL+AY+IQGQ+ I
Sbjct: 181 IPYQPMPASSPVICAGGQDRC---SDAAGYPHAT------HDLEGPPLDAYSIQGQHTIS 231
Query: 240 QPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYW-GLDASAQTTSHELTIPNDL 298
DL KL+Q+A QQSHF M HG TGF+GI+SSSPEVKGYW LDAS QTT HELTIPN+L
Sbjct: 232 PLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDASTQTT-HELTIPNNL 290
Query: 299 IGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSE 358
IGCIIGRQGA INEIRQMSGAQIKIANPVEGS+ RQVTITGSAASISLAQYLIN RLSSE
Sbjct: 291 IGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAASISLAQYLINARLSSE 350
Query: 359 TGGMGSS 365
GMG S
Sbjct: 351 K-GMGCS 356
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 479 bits (1233), Expect = e-135
Identities = 263/373 (70%), Positives = 291/373 (78%), Gaps = 44/373 (11%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE SPPKG TI
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLE----SPPKGATI 208
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
PYRPKP+S+PVIFAGGQ AYTIQGQYAIP
Sbjct: 209 PYRPKPASTPVIFAGGQ-------------------------------AYTIQGQYAIPH 237
Query: 241 PD-LTKLHQLAMQQSHF-PMTHGNTGFSGIE---SSSPEVKGYW----GLDASAQTTSHE 291
PD LTKLHQLAMQQ+ F P+ N F G + SS E + GLDAS ++HE
Sbjct: 238 PDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHE 297
Query: 292 LTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 351
LTIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN EGS++RQ+TITG+ A+ISLAQYLI
Sbjct: 298 LTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLI 357
Query: 352 NVRLSSETGGMGS 364
N RL+SE GMG+
Sbjct: 358 NARLTSEVTGMGT 370
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 405 bits (1041), Expect = e-113
Identities = 234/372 (62%), Positives = 263/372 (70%), Gaps = 68/372 (18%)
Query: 1 MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIIT 60
M++ V EGGLNVTLTIRLLMHGKEVGSIIGKKGE+VKKMREESGARINISEGNCPERI+T
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVT 92
Query: 61 LAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKI 120
+ GPT+AIFKAFAMI K EEDI +SM+NS A S+PPVTLRLVVPASQCGSLIGKGG KI
Sbjct: 93 ITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKI 152
Query: 121 KEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTI 180
KEIRESTGAQVQVAGDMLPNSTERA+TI+G P +II+CVKQICVVMLE +
Sbjct: 153 KEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTI-------- 204
Query: 181 PYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQ 240
Q +Y + PH PDL
Sbjct: 205 ----------------QGQY-------AIPH--------PDL------------------ 215
Query: 241 PDLTKLHQLAMQQSHF-PMTHGNTGFSGIE---SSSPEVKGYW----GLDASAQTTSHEL 292
TKLHQLAMQQ+ F P+ N F G + SS E + GLDAS ++HEL
Sbjct: 216 ---TKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHEL 272
Query: 293 TIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLIN 352
TIPNDLIGCIIGRQG KINEIRQMSGAQIKIAN EGS++RQ+TITG+ A+ISLAQYLIN
Sbjct: 273 TIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLIN 332
Query: 353 VRLSSETGGMGS 364
RL+SE GMG+
Sbjct: 333 ARLTSEVTGMGT 344
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 345 bits (884), Expect = 5e-95
Identities = 195/363 (53%), Positives = 242/363 (66%), Gaps = 55/363 (15%)
Query: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LE SPPKG TIPY P
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILE----SPPKGATIPYHPSL 186
Query: 187 SSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQY-AIPQPDLTK 245
S V+ + Q +++QGQY A+ ++TK
Sbjct: 187 SLGTVLLSANQ-------------------------------GFSVQGQYGAVTPAEVTK 215
Query: 246 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGR 305
L QL+ SH + ++P V GLD QT+S E +PNDLIGC+IGR
Sbjct: 216 LQQLS---SH-----------AVPFATPSVVP--GLDPGTQTSSQEFLVPNDLIGCVIGR 259
Query: 306 QGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGGM 362
QG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI L S +GG
Sbjct: 260 QGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGT 319
Query: 363 GSS 365
SS
Sbjct: 320 PSS 322
Score = 67.0 bits (162), Expect = 3e-11
Identities = 69/284 (24%), Positives = 116/284 (40%), Gaps = 68/284 (23%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG---NCPERIITLAGPTNAIFK 70
+T+RL++ + GS+IGK G +K++RE +GA++ ++ N ER +T++G +AI
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
Query: 71 AFAMI----------------------------------------------IDKLEEDIS 84
I + KL++ S
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 85 SSMTNSTAASRPPV-------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM 137
++ +T + P + + +VP G +IG+ G KI EIR+ +GA +++ G+
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQ 280
Query: 138 LPNSTERAITIAGIPQSIIECVKQICVVMLETLS-------QSPPKGVTIPYRPKPSSSP 190
+ ER +TI G P S I + + LET S P + P+ P ++ P
Sbjct: 281 AEGAGERHVTITGSPVS-IALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALP 339
Query: 191 VIFAGGQDR-YSTGSDSASFPHTTPSMCLNPDLEGPP--LEAYT 231
G Y+ + P + L P GPP L AYT
Sbjct: 340 TAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYT 383
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 345 bits (884), Expect = 5e-95
Identities = 195/363 (53%), Positives = 242/363 (66%), Gaps = 55/363 (15%)
Query: 7 EGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTN 66
E L++TLT+R+LMHGKEVGSIIGKKGE+VK++RE+S ARI ISEG+CPERI T+ G T
Sbjct: 11 EPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPERITTITGSTA 70
Query: 67 AIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
A+F A +MI KL+ED+ ++ N SRPPVTLRLV+PASQCGSLIGK G KIKEIRE+
Sbjct: 71 AVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRET 130
Query: 127 TGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+LE SPPKG TIPY P
Sbjct: 131 TGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILE----SPPKGATIPYHPSL 186
Query: 187 SSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQY-AIPQPDLTK 245
S V+ + Q +++QGQY A+ ++TK
Sbjct: 187 SLGTVLLSANQ-------------------------------GFSVQGQYGAVTPAEVTK 215
Query: 246 LHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGR 305
L QL+ SH + ++P V GLD QT+S E +PNDLIGC+IGR
Sbjct: 216 LQQLS---SH-----------AVPFATPSVVP--GLDPGTQTSSQEFLVPNDLIGCVIGR 259
Query: 306 QGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRL---SSETGGM 362
QG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+LAQYLI L S +GG
Sbjct: 260 QGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGT 319
Query: 363 GSS 365
SS
Sbjct: 320 PSS 322
Score = 67.0 bits (162), Expect = 3e-11
Identities = 69/284 (24%), Positives = 116/284 (40%), Gaps = 68/284 (23%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG---NCPERIITLAGPTNAIFK 70
+T+RL++ + GS+IGK G +K++RE +GA++ ++ N ER +T++G +AI
Sbjct: 102 VTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIIL 161
Query: 71 AFAMI----------------------------------------------IDKLEEDIS 84
I + KL++ S
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 85 SSMTNSTAASRPPV-------TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM 137
++ +T + P + + +VP G +IG+ G KI EIR+ +GA +++ G+
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQ 280
Query: 138 LPNSTERAITIAGIPQSIIECVKQICVVMLETLS-------QSPPKGVTIPYRPKPSSSP 190
+ ER +TI G P S I + + LET S P + P+ P ++ P
Sbjct: 281 AEGAGERHVTITGSPVS-IALAQYLITACLETAKSTSGGTPSSAPADLPAPFSPPLTALP 339
Query: 191 VIFAGGQDR-YSTGSDSASFPHTTPSMCLNPDLEGPP--LEAYT 231
G Y+ + P + L P GPP L AYT
Sbjct: 340 TAPPGLLGTPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYT 383
>gi|9966803 poly(rC) binding protein 4 isoform a [Homo sapiens]
Length = 424
Score = 261 bits (666), Expect = 9e-70
Identities = 167/383 (43%), Positives = 209/383 (54%), Gaps = 110/383 (28%)
Query: 42 ESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLR 101
+S ARI ISEG+CPERI T+ G T A+F A +MI KL+ED+ ++ N SRPPVTLR
Sbjct: 12 QSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLR 71
Query: 102 LVVPASQCGSLIGKGGCKIK---EIR---------------------------------- 124
LV+PASQCGSLIGK G KIK E+R
Sbjct: 72 LVIPASQCGSLIGKAGTKIKEIREVRGEIYHPQGIRGKGAVVRGVLGLWRPPHLESSEPG 131
Query: 125 ------------------ESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVM 166
++TGAQVQVAGD+LPNSTERA+T++G+P +II CV+QIC V+
Sbjct: 132 QPFSGLWEQPEVAPVLCLQTTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVI 191
Query: 167 LETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPP 226
LE SPPKG TIPY P S V+ + Q
Sbjct: 192 LE----SPPKGATIPYHPSLSLGTVLLSANQ----------------------------- 218
Query: 227 LEAYTIQGQY-AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASA 285
+++QGQY A+ ++TKL QL+ SH + ++P V GLD
Sbjct: 219 --GFSVQGQYGAVTPAEVTKLQQLS---SH-----------AVPFATPSVVP--GLDPGT 260
Query: 286 QTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASIS 345
QT+S E +PNDLIGC+IGRQG+KI+EIRQMSGA IKI N EG+ +R VTITGS SI+
Sbjct: 261 QTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEGAGERHVTITGSPVSIA 320
Query: 346 LAQYLINVRL---SSETGGMGSS 365
LAQYLI L S +GG SS
Sbjct: 321 LAQYLITACLETAKSTSGGTPSS 343
Score = 49.3 bits (116), Expect = 5e-06
Identities = 42/139 (30%), Positives = 62/139 (44%), Gaps = 12/139 (8%)
Query: 103 VVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQI 162
+VP G +IG+ G KI EIR+ +GA +++ G+ + ER +TI G P S I + +
Sbjct: 268 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKI-GNQAEGAGERHVTITGSPVS-IALAQYL 325
Query: 163 CVVMLETLS-------QSPPKGVTIPYRPKPSSSPVIFAGGQDR-YSTGSDSASFPHTTP 214
LET S P + P+ P ++ P G Y+ + P
Sbjct: 326 ITACLETAKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGTPYAISLSNFIGLKPMP 385
Query: 215 SMCLNPDLEGPP--LEAYT 231
+ L P GPP L AYT
Sbjct: 386 FLALPPASPGPPPGLAAYT 404
Score = 35.4 bits (80), Expect = 0.081
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 11/97 (11%)
Query: 25 VGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
+G +IG++G + ++R+ SGA I I +EG ER +T+ G +I A +I LE
Sbjct: 274 IGCVIGRQGSKISEIRQMSGAHIKIGNQAEG-AGERHVTITGSPVSIALAQYLITACLET 332
Query: 82 DISSSMTNSTAAS-------RPPVTLRLVVPASQCGS 111
S+S ++A PP+T P G+
Sbjct: 333 AKSTSGGTPSSAPADLPAPFSPPLTALPTAPPGLLGT 369
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 155 bits (392), Expect = 5e-38
Identities = 120/423 (28%), Positives = 186/423 (43%), Gaps = 85/423 (20%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K ++L+ +S+SP
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
Query: 176 KGVTIPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT- 213
KG PY P +P P+ GG DR G P +
Sbjct: 219 KGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRR 278
Query: 214 ----------------------PSMCLNPDLEGPP------LEAY--------TIQGQYA 237
S N L PP L AY G
Sbjct: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVG 338
Query: 238 IPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPND 297
+ S + M + G SG + S +G +G D + ++TIP D
Sbjct: 339 FSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYG-DLGGPIITTQVTIPKD 397
Query: 298 LIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSS 357
L G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+ +
Sbjct: 398 LAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
Query: 358 ETG 360
+G
Sbjct: 458 YSG 460
Score = 46.2 bits (108), Expect = 5e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLETLSQSPP 175
+K+I + E L P
Sbjct: 100 ILKKIIPTLEEGLQLPSP 117
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 154 bits (390), Expect = 9e-38
Identities = 119/414 (28%), Positives = 183/414 (44%), Gaps = 85/414 (20%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K ++L+ +S+SP
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
Query: 176 KGVTIPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT- 213
KG PY P +P P+ GG DR G P +
Sbjct: 219 KGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRR 278
Query: 214 ----------------------PSMCLNPDLEGPP------LEAY--------TIQGQYA 237
S N L PP L AY G
Sbjct: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVG 338
Query: 238 IPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPND 297
+ S + M + G SG + S +G +G D + ++TIP D
Sbjct: 339 FSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYG-DLGGPIITTQVTIPKD 397
Query: 298 LIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 351
L G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+
Sbjct: 398 LAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
Score = 46.2 bits (108), Expect = 5e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLETLSQSPP 175
+K+I + E L P
Sbjct: 100 ILKKIIPTLEEGLQLPSP 117
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 154 bits (390), Expect = 9e-38
Identities = 119/414 (28%), Positives = 183/414 (44%), Gaps = 85/414 (20%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMI 75
+R+L+ K G++IGK G+++K +R + A +++ + + PERI++++ I + I
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKI 104
Query: 76 IDKLEEDISSSMTNSTAASRPPVT--------------------LRLVVPASQCGSLIGK 115
I LEE + + + TA S+ P+ LRL++ S G +IG
Sbjct: 105 IPTLEEGLQ--LPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGV 162
Query: 116 GGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPP 175
G KIKE+RE+T +++ + P+ST+R + I G P ++EC+K ++L+ +S+SP
Sbjct: 163 KGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIK----IILDLISESPI 218
Query: 176 KGVTIPYRP---------------------KPSSSPVIFAGGQDRYSTGSDSASFPHTT- 213
KG PY P +P P+ GG DR G P +
Sbjct: 219 KGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRR 278
Query: 214 ----------------------PSMCLNPDLEGPP------LEAY--------TIQGQYA 237
S N L PP L AY G
Sbjct: 279 DYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVG 338
Query: 238 IPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPND 297
+ S + M + G SG + S +G +G D + ++TIP D
Sbjct: 339 FSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYG-DLGGPIITTQVTIPKD 397
Query: 298 LIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLI 351
L G IIG+ G +I +IR SGA IKI P+EGS DR +TITG+ I AQYL+
Sbjct: 398 LAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLL 451
Score = 46.2 bits (108), Expect = 5e-05
Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 9 GLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPT 65
G + +RLL+H G IIG KG +K++RE + I + + CP +R++ + G
Sbjct: 140 GSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKP 199
Query: 66 NAIFKAFAMIIDKLEE 81
+ + + +I+D + E
Sbjct: 200 DRVVECIKIILDLISE 215
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/58 (39%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 26 GSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEE 81
GSIIGK G+ +K++R ESGA I I E +RIIT+ G + I A ++ + +++
Sbjct: 400 GSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQ 457
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
V LR+++ + G++IGKGG IK +R A V V P ER ++I+ ++I E
Sbjct: 43 VELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILSISADIETIGE 99
Query: 158 CVKQICVVMLETLSQSPP 175
+K+I + E L P
Sbjct: 100 ILKKIIPTLEEGLQLPSP 117
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 105 bits (263), Expect = 5e-23
Identities = 107/427 (25%), Positives = 189/427 (44%), Gaps = 87/427 (20%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
Query: 122 EIRESTGAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG-- 177
+ E +GA VQ++ D + N ER +T++G P+ + V+ ++++ + + P G
Sbjct: 172 AVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSGSC 226
Query: 178 VTIPY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP--------- 210
+ I Y P+ SP A G ++ + A+FP
Sbjct: 227 LNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGN 286
Query: 211 ---------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHFP 257
+T S N + G L G A P + LA S
Sbjct: 287 DLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEAS 346
Query: 258 M-------THGNTGFSGIESSSPEVKGYWG----LDASAQTTSH----------ELTIPN 296
T G + +++ GY+G L ASA + E+ +P
Sbjct: 347 ASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPE 406
Query: 297 DLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLINV 353
+L+G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI
Sbjct: 407 NLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQ 466
Query: 354 RLSSETG 360
R++ E G
Sbjct: 467 RITYEQG 473
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 102 bits (253), Expect = 7e-22
Identities = 109/451 (24%), Positives = 192/451 (42%), Gaps = 111/451 (24%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG-----NCPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 71 AFAMIIDKLEE---------------------------DISSSMTNSTAASRPPVT---- 99
I +K+ E + SS T + ++ P+T
Sbjct: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRA 171
Query: 100 --LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIAGIPQSI 155
++++VP S G +IGKGG +K + E +GA VQ++ D + N ER +T++G P+
Sbjct: 172 NQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVVTVSGEPEQN 230
Query: 156 IECVKQICVVMLETLSQSPPKG--VTIPY--------RPKPSSSP----------VIFAG 195
+ V+ ++++ + + P G + I Y P+ SP A
Sbjct: 231 RKAVE----LIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAA 286
Query: 196 GQDRYSTGSDSASFP------------------HTTPSMCLNPDLEGPPLEAYTIQGQYA 237
G ++ + A+FP +T S N + G L G A
Sbjct: 287 GLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALA 346
Query: 238 I----PQPDLTKLHQLAMQQSHFPM-------THGNTGFSGIESSSPEVKGYWG----LD 282
P + LA S T G + +++ GY+G L
Sbjct: 347 AAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLA 406
Query: 283 ASAQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEG 329
ASA + E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G
Sbjct: 407 ASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPG 466
Query: 330 STDRQVTITGSAASISLAQYLINVRLSSETG 360
+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 467 TRNRKVTITGTPAATQAAQYLITQRITYEQG 497
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 85.9 bits (211), Expect = 5e-17
Identities = 89/368 (24%), Positives = 154/368 (41%), Gaps = 52/368 (14%)
Query: 23 KEVGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKA---FAMIID 77
K VG IIG+ GE + +++ ESG +I I+ PER L G +I +A I+D
Sbjct: 87 KMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVD 146
Query: 78 K------LEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ- 130
+ DI S+ T +++PAS+ G +IG+GG IK+++E TG +
Sbjct: 147 RCRNGPGFHNDIDSNSTIQ----------EILIPASKVGLVIGRGGETIKQLQERTGVKM 196
Query: 131 VQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYR------- 183
V + LP ++ + I G + + + + ++ E Q+ +GV +
Sbjct: 197 VMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREK-DQADFRGVRGDFNSRMGGGS 255
Query: 184 -----PKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAI 238
P+ + VI G+ +D+ P ++P+ A + G
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPE------RAAQVMG---- 305
Query: 239 PQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGY--WGLDASAQTTSHELTIPN 296
PD + H + GF G+ ++ +G W + A T+P
Sbjct: 306 -PPDRCQ-HAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPA 363
Query: 297 DLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINV 353
D G +IG+ G I I Q SGA +++ ++D R+ TI G I +A+ LI+
Sbjct: 364 DKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDE 423
Query: 354 RLSSETGG 361
++ G
Sbjct: 424 KVGGTNLG 431
Score = 72.0 bits (175), Expect = 8e-13
Identities = 73/253 (28%), Positives = 106/253 (41%), Gaps = 33/253 (13%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKL--- 79
VG +IG+ GE +KK++ ++G RI +G PER + GP + A A II +L
Sbjct: 265 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHA-AHIISELILT 323
Query: 80 --EEDISSSMTN-----------STAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRES 126
E D + S A + VPA +CG +IGKGG IK I +
Sbjct: 324 AQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQ 383
Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRP 184
+GA V++ + PNS R TI G+PQ I ++ +++ G +
Sbjct: 384 SGAHVELQRNPPPNSDPNLRRFTIRGVPQQI-----EVARQLIDEKVGGTNLGAPGAFGQ 438
Query: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP---DLEGPPLEAYTIQGQYAIPQP 241
P S P A S FP+ + NP + GPP A+ QG + Q
Sbjct: 439 SPFSQPP--APPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPP--AFLTQGWGSTYQA 494
Query: 242 DLTKLHQLAMQQS 254
Q+ QQS
Sbjct: 495 WQQPTQQVPSQQS 507
Score = 49.7 bits (117), Expect = 4e-06
Identities = 74/324 (22%), Positives = 127/324 (39%), Gaps = 51/324 (15%)
Query: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEGNCP---ERIITLAGPTNAIFKAFA 73
+L+ +VG +IG+ GE++K+++E +G + + I +G P ++ + + G + +A
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 74 MIIDKLEEDISSSMTNSTAASRPPV---TLRLVVPASQCGSLIGKGGCKIKEIRESTGAQ 130
M+++ + E + + ++ + VP G +IG+ G IK+I+ G +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 131 VQVAGDMLPNSTERAITIAGIP---QSIIECVKQICVVMLE------------------T 169
+Q D S ERA + G P Q + ++ + E
Sbjct: 287 IQFKPDD-GISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGD 345
Query: 170 LSQSPPKGV-TIPYR-PKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPL 227
S P GV I Y P VI GG++ S S + + N D P L
Sbjct: 346 WSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSD---PNL 402
Query: 228 EAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQT 287
+TI+G +PQ ++A Q + N G G SP +
Sbjct: 403 RRFTIRG---VPQQ-----IEVARQLIDEKVGGTNLGAPGAFGQSP--------FSQPPA 446
Query: 288 TSHELTIPNDLIGCIIGRQGAKIN 311
H+ T P GC AK+N
Sbjct: 447 PPHQNTFPPRSSGC-FPNMAAKVN 469
Score = 47.4 bits (111), Expect = 2e-05
Identities = 23/63 (36%), Positives = 39/63 (61%)
Query: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 348
+ E +P+ ++G IIGR G +I+ I+ SG +I+IA+ G +R +TG+ SI A+
Sbjct: 79 TEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAK 138
Query: 349 YLI 351
L+
Sbjct: 139 RLL 141
Score = 40.8 bits (94), Expect = 0.002
Identities = 63/280 (22%), Positives = 104/280 (37%), Gaps = 34/280 (12%)
Query: 95 RPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
R +T VP G +IG+GG +I I+ +G ++Q+A + ER + G P+S
Sbjct: 75 RTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASES-SGIPERPCVLTGTPES 133
Query: 155 IIECVKQICVVMLETLSQSP------PKGVTIPYRPKPSSSP--VIFAGGQDRYSTGSDS 206
IE K++ +++ P TI P+S VI GG+ T
Sbjct: 134 -IEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGE----TIKQL 188
Query: 207 ASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFS 266
M + L + I G D K+ Q F
Sbjct: 189 QERTGVKMVMIQDGPLPTGADKPLRITG-------DAFKVQQAREMVLEIIREKDQADFR 241
Query: 267 GIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP 326
G+ G ++ S +P +G +IGR G I +I+ +G +I+ P
Sbjct: 242 GVRGDFNSRMGGGSIEVS---------VPRFAVGIVIGRNGEMIKKIQNDAGVRIQF-KP 291
Query: 327 VEG-STDRQVTITGSAASISLAQYLIN--VRLSSETGGMG 363
+G S +R + G A ++I+ + + E G G
Sbjct: 292 DDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFG 331
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 80.5 bits (197), Expect = 2e-15
Identities = 85/354 (24%), Positives = 145/354 (40%), Gaps = 37/354 (10%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG IIG+ GE + K++++SG ++ IS G PER ++L G ++ KA M+ D +
Sbjct: 156 VGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRG 215
Query: 83 ISS---SMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLP 139
++ + +++PA + G +IGKGG IK+++E G ++ + D
Sbjct: 216 RGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQ 275
Query: 140 N-STERAITIAGIPQSIIECVKQICVVMLETLSQSPP--------------KGVTIPYRP 184
N + ++ + I G P V+Q C ++++ L + G+ +P P
Sbjct: 276 NTNVDKPLRIIGDPYK----VQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPV-P 330
Query: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLT 244
+ S VI G+ +D+ D GP A+ +
Sbjct: 331 RHSVGVVIGRSGEMIKKIQNDAG-----VRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
Query: 245 KLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIG 304
L +S P G G +G WG T S IP G +IG
Sbjct: 386 INDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKCGLVIG 441
Query: 305 RQGAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRL 355
R G + I Q +GA ++I+ + + D + I GS I A+ LI ++
Sbjct: 442 RGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKI 495
Score = 68.2 bits (165), Expect = 1e-11
Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 37/230 (16%)
Query: 25 VGSIIGKKGESVKKMREESGARINISE--GNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG +IG+ GE +KK++ ++G RI + G PE+I + GP + A +I D L+
Sbjct: 334 VGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSL 393
Query: 83 ISSSMTNSTAASRPPV----------------TLRLVVPASQCGSLIGKGGCKIKEIRES 126
S PP + +P +CG +IG+GG +K I +
Sbjct: 394 RSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQ 453
Query: 127 TGAQVQVAGDMLPNSTE--RAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRP 184
TGA V+++ + PN + I G PQ I+ KQ+ +E G P P
Sbjct: 454 TGAFVEISRQLPPNGDPNFKLFIIRGSPQQ-IDHAKQLIEEKIE--------GPLCPVGP 504
Query: 185 KPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQG 234
P AG ++ G + P P GPP Y QG
Sbjct: 505 GPGGPGP--AGPMGPFNPGPFNQGPPGAP------PHAGGPPPHQYPPQG 546
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 17/197 (8%)
Query: 8 GGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAG 63
GG N T+ ++ GK G +IGK GE++K+++E +G ++ + S+ ++ + + G
Sbjct: 229 GGQNGTVQEIMIPAGK-AGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIG 287
Query: 64 PTNAIFKAFAMIIDKL-EEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKE 122
+ +A M++D L E D + SR + + VP G +IG+ G IK+
Sbjct: 288 DPYKVQQACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKK 347
Query: 123 IRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPY 182
I+ G ++Q D E+ I G P E +I +L++L P
Sbjct: 348 IQNDAGVRIQFKQDD-GTGPEKIAHIMG-PPDRCEHAARIINDLLQSLRSGP-------- 397
Query: 183 RPKPSSSPVIFAGGQDR 199
P P P + GG+ R
Sbjct: 398 -PGPPGGPGMPPGGRGR 413
Score = 53.1 bits (126), Expect = 4e-07
Identities = 25/73 (34%), Positives = 47/73 (64%)
Query: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQ 348
+ E +P+ ++G IIGR G +IN+I+Q SG +++I+ G +R V++TG+ S+ A+
Sbjct: 146 TEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPESVQKAK 205
Query: 349 YLINVRLSSETGG 361
+++ +S GG
Sbjct: 206 MMLDDIVSRGRGG 218
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 5/77 (6%)
Query: 81 EDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--L 138
+ ISS + R +T VP G +IG+GG +I +I++ +G +VQ++ D L
Sbjct: 128 DSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGL 187
Query: 139 PNSTERAITIAGIPQSI 155
P ER++++ G P+S+
Sbjct: 188 P---ERSVSLTGAPESV 201
Score = 30.0 bits (66), Expect = 3.4
Identities = 18/71 (25%), Positives = 31/71 (43%)
Query: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 350
++ +P +G +IGR G I +I+ +G +I+ ++ I G A +
Sbjct: 326 DVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCEHAARI 385
Query: 351 INVRLSSETGG 361
IN L S G
Sbjct: 386 INDLLQSLRSG 396
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 74.7 bits (182), Expect = 1e-13
Identities = 85/360 (23%), Positives = 149/360 (41%), Gaps = 37/360 (10%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG IIG+ GE + ++++ESG +I I+ G PER L G ++ A ++D++ E
Sbjct: 112 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSA-KRLLDQIVEK 170
Query: 83 ISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNS- 141
+ +++PAS+ G +IGKGG IK+++E G ++ + D N+
Sbjct: 171 GRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTG 230
Query: 142 TERAITIAGIPQSIIECVKQICVVMLET-----------LSQSPPKGVTIPYRPKPSSSP 190
++ + I G P + + + + ++ + +G+ +P P+ +
Sbjct: 231 ADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPI-PRFAVGI 289
Query: 191 VIFAGGQDRYSTGSDSASFPHTTPSMCLNPD----LEGPPLEAYTIQGQYAIPQPDLTKL 246
VI G+ +D+ P P+ + GPP Q+A +T L
Sbjct: 290 VIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRC-----QHA--AEIITDL 342
Query: 247 HQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQ 306
L Q+ P G G G +G W + +P G IIG+
Sbjct: 343 --LRSVQAGNP---GGPGPGG--RGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKG 395
Query: 307 GAKINEIRQMSGAQIKIANPVEGSTD---RQVTITGSAASISLAQYLINVRLSSETGGMG 363
G I I Q SGA+I++ + D + TI G+ I A+ LI ++ +G
Sbjct: 396 GETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG 455
Score = 69.7 bits (169), Expect = 4e-12
Identities = 55/187 (29%), Positives = 87/187 (46%), Gaps = 26/187 (13%)
Query: 25 VGSIIGKKGESVKKMREESGARINIS--EGNCPERIITLAGPTNAIFKAFAMIIDKLEED 82
VG +IG+ GE +KK++ ++G RI +G PERI + GP + A +I D L
Sbjct: 287 VGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSV 346
Query: 83 ISSSMTNSTAASR------------PPVTLR---LVVPASQCGSLIGKGGCKIKEIREST 127
+ + R PP L+ +VP + G +IGKGG IK I + +
Sbjct: 347 QAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQS 406
Query: 128 GAQVQVAGDMLPNS--TERAITIAGIPQSIIECVKQICVVMLETLSQSP--PKGVTIPYR 183
GA++++ + PN+ + TI G PQ I+ +Q ++E P P G +P+
Sbjct: 407 GARIELQRNPPPNADPNMKLFTIRGTPQQ-IDYARQ----LIEEKIGGPVNPLGPPVPHG 461
Query: 184 PKPSSSP 190
P P
Sbjct: 462 PHGVPGP 468
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/69 (34%), Positives = 41/69 (59%)
Query: 284 SAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAAS 343
S + E +P+ ++G IIGR G +I+ I+Q SG +I+IA G +R +TG+ S
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPES 156
Query: 344 ISLAQYLIN 352
+ A+ L++
Sbjct: 157 VQSAKRLLD 165
Score = 45.8 bits (107), Expect = 6e-05
Identities = 65/278 (23%), Positives = 107/278 (38%), Gaps = 35/278 (12%)
Query: 94 SRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDM--LPNSTERAITIAGI 151
SR +T VP G +IG+GG +I I++ +G ++Q+A D LP ER+ + G
Sbjct: 97 SRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGT 153
Query: 152 PQSIIECVKQICVVMLETLSQSP-------PKGVTIPYRPKPSSSPVIFAGGQDRYSTGS 204
P+S ++ K++ ++E +P P S + ++ G +
Sbjct: 154 PES-VQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQ 212
Query: 205 DSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTG 264
+ A + P G Y + Q L +L Q F G
Sbjct: 213 ERAGVKMV--MIQDGPQNTGADKPLRITGDPYKVQQAKEMVL-ELIRDQGGFREVRNEYG 269
Query: 265 FSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA 324
+ G G+D + IP +G +IGR G I +I+ +G +I+
Sbjct: 270 --------SRIGGNEGID---------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQF- 311
Query: 325 NPVEGST-DRQVTITGSAASISLAQYLINVRLSSETGG 361
P +G+T +R ITG A +I L S G
Sbjct: 312 KPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAG 349
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/166 (21%), Positives = 77/166 (46%), Gaps = 8/166 (4%)
Query: 18 LLMHGKEVGSIIGKKGESVKKMREESGAR-INISEG---NCPERIITLAGPTNAIFKAFA 73
+++ + G +IGK GE++K+++E +G + + I +G ++ + + G + +A
Sbjct: 190 IMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKE 249
Query: 74 MIIDKLEEDISSSMTNSTAASR--PPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
M+++ + + + SR + + +P G +IG+ G IK+I+ G ++
Sbjct: 250 MVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRI 309
Query: 132 QVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177
Q D + ER I G P + +I +L ++ P G
Sbjct: 310 QFKPDD-GTTPERIAQITG-PPDRCQHAAEIITDLLRSVQAGNPGG 353
Score = 35.8 bits (81), Expect = 0.062
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 24 EVGSIIGKKGESVKKMREESGARINISEGNCPE-----RIITLAGPTNAIFKAFAMIIDK 78
+ G IIGK GE++K + ++SGARI + P ++ T+ G I A +I +K
Sbjct: 387 KTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEK 446
Query: 79 L 79
+
Sbjct: 447 I 447
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 74.7 bits (182), Expect = 1e-13
Identities = 50/165 (30%), Positives = 88/165 (53%), Gaps = 21/165 (12%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 71 AFAMIIDKLEEDISSSMTNSTAAS--RPPVTL--------RLVVPASQCGSLIGKGGCKI 120
+ I +K+ E I +MT + +P T+ +L+VP S G +IGKGG +
Sbjct: 95 VHSFIAEKVRE-IPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATV 153
Query: 121 KEIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQI 162
K + E +GA VQ++ P N ER +T++G P+ + + V I
Sbjct: 154 KAVMEQSGAWVQLS--QKPEGINLQERVVTVSGEPEQVHKAVSAI 196
Score = 60.8 bits (146), Expect = 2e-09
Identities = 31/78 (39%), Positives = 53/78 (67%), Gaps = 3/78 (3%)
Query: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 347
E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+ +R+VTITGS A+ A
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAA 469
Query: 348 QYLINVRLSSETGGMGSS 365
QYLI+ R++ E G S+
Sbjct: 470 QYLISQRVTYEQGVRASN 487
Score = 54.3 bits (129), Expect = 2e-07
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)
Query: 17 RLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKAF 72
+L++ G IIGK G +VK + E+SGA + +S+ N ER++T++G + KA
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 73 AMIIDKLEEDISSS-------------MTNSTAASRPPVTLRLVVPASQCGSLIGKGG 117
+ I+ K++ED SS + NS P + V+PA+ S G
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAAASAAAASG 251
Score = 47.8 bits (112), Expect = 2e-05
Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query: 92 AASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVA--GDMLPNSTERAITIA 149
AA + + VP + G+++GKGG + E +E TGA++Q++ G+ LP + R +TI
Sbjct: 401 AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTIT 460
Query: 150 GIP 152
G P
Sbjct: 461 GSP 463
Score = 39.3 bits (90), Expect = 0.006
Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Query: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGST--DRQVTITGSAASISLA 347
+L +PN G IIG+ GA + + + SGA ++++ EG +R VT++G + A
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKA 192
Score = 33.5 bits (75), Expect = 0.31
Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
Query: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASISLA 347
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R + G+A +++
Sbjct: 36 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
Query: 348 QYLI 351
I
Sbjct: 96 HSFI 99
Score = 29.6 bits (65), Expect = 4.4
Identities = 13/27 (48%), Positives = 22/27 (81%)
Query: 25 VGSIIGKKGESVKKMREESGARINISE 51
VG+I+GK G+++ + +E +GARI IS+
Sbjct: 418 VGAILGKGGKTLVEYQELTGARIQISK 444
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
Query: 133 VAGDMLPNSTERAI 146
V D P+ E I
Sbjct: 502 VPRDQTPDENEEVI 515
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 29/213 (13%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
Query: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
A I+ KL E + M T+S S + L +P
Sbjct: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
Query: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVML 167
G++IGK G IK++ GA +++A P+ +ER + I G P++ + +I +
Sbjct: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLK 454
Query: 168 ETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
E +P + V + P ++ VI GG+
Sbjct: 455 EENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 487
Score = 59.7 bits (143), Expect = 4e-09
Identities = 66/268 (24%), Positives = 115/268 (42%), Gaps = 16/268 (5%)
Query: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ E
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
Query: 160 KQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLN 219
+ I +M + ++ IP + + V G++ G + H T +
Sbjct: 256 RMILEIMQKEADETK-LAEEIPLKILAHNGLVGRLIGKE----GRNLKKIEHETGTKITI 310
Query: 220 PDLEG----PPLEAYTIQGQY---AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSS 272
L+ P T++G A + ++ K + A + + + FS +
Sbjct: 311 SSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHH 370
Query: 273 PEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS-- 330
+ + + + L IP +G IIG++GA I ++ + +GA IKIA P EG
Sbjct: 371 -QFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDV 428
Query: 331 TDRQVTITGSAASISLAQYLINVRLSSE 358
++R V ITG + AQ I +L E
Sbjct: 429 SERMVIITGPPEAQFKAQGRIFGKLKEE 456
Score = 55.5 bits (132), Expect = 8e-08
Identities = 37/160 (23%), Positives = 82/160 (51%), Gaps = 15/160 (9%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQI 162
++ ++ D+ + ER IT+ G ++ IE +K++
Sbjct: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKL 345
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 73.9 bits (180), Expect = 2e-13
Identities = 86/358 (24%), Positives = 149/358 (41%), Gaps = 61/358 (17%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
Query: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKP 186
++ ++ D+ + ER IT+ G ++ +I + E + +
Sbjct: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFEND-----MLAVNQQA 360
Query: 187 SSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAY----TIQGQYAIPQPD 242
+ P + +STG S P P PP Y T G ++ P
Sbjct: 361 NLIPGLNLSALGIFSTGLSVLS-PPAGPR-------GAPPAAPYHPFTTHSGYFSSLYPH 412
Query: 243 LTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCI 302
HQ FP H S PE + L IP +G I
Sbjct: 413 ----HQF----GPFPHHH----------SYPEQE------------IVNLFIPTQAVGAI 442
Query: 303 IGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQYLINVRLSSE 358
IG++GA I ++ + +GA IKIA P EG ++R V ITG + AQ I +L E
Sbjct: 443 IGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 499
Score = 73.9 bits (180), Expect = 2e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 490 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 544
Query: 133 VAGDMLPNSTERAI 146
V D P+ E I
Sbjct: 545 VPRDQTPDENEEVI 558
Score = 43.1 bits (100), Expect = 4e-04
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
+ L +P G++IGK G IK++ GA +++A P+ +ER + I G P++ +
Sbjct: 430 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 489
Query: 160 KQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
+I + E +P + V + P ++ VI GG+
Sbjct: 490 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 530
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 269 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 328
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 329 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 383
Query: 133 VAGDMLPNSTERAI 146
V D P+ ++ I
Sbjct: 384 VPRDQTPDENDQVI 397
Score = 59.3 bits (142), Expect = 5e-09
Identities = 53/230 (23%), Positives = 97/230 (42%), Gaps = 48/230 (20%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
+++L H VG +IGK+G ++KK+ +++ +I IS PER IT+ G +
Sbjct: 140 LKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCR 199
Query: 71 AFAMIIDKLEEDISSSM----------------------TNSTAASRPPVT--------- 99
A I+ K+ E + + +S+A PP +
Sbjct: 200 AEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSS 259
Query: 100 ---------LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
+++ +PA G++IGK G IK++ A +++A P+S R + I G
Sbjct: 260 FMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITG 319
Query: 151 IPQSIIECVKQICVVMLETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
P++ + +I + E P + V + P ++ VI GG+
Sbjct: 320 PPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK 369
Score = 38.5 bits (88), Expect = 0.010
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQY 349
++ IP +G IIG++G I ++ + + A IKIA P S R V ITG + AQ
Sbjct: 270 QVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQG 329
Query: 350 LINVRLSSE 358
I +L E
Sbjct: 330 RIYGKLKEE 338
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 70.5 bits (171), Expect = 2e-12
Identities = 41/137 (29%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 13 TLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIF 69
T T+ L + VG+IIGK+G+ +K++ +GA I I+ P+ R++ + GP A F
Sbjct: 405 TETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQF 464
Query: 70 KAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGA 129
KA I K++E+ S + + VP+ G +IGKGG + E++ + A
Sbjct: 465 KAQGRIYGKIKEENFVSPKEEV-----KLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSA 519
Query: 130 QVQVAGDMLPNSTERAI 146
+V V D P+ ++ +
Sbjct: 520 EVVVPRDQTPDENDQVV 536
Score = 54.3 bits (129), Expect = 2e-07
Identities = 80/398 (20%), Positives = 154/398 (38%), Gaps = 106/398 (26%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI----SEGNCPERIITLAGP--TNA 67
L +RLL+ + VG+IIGK+G +++ + +++ ++I++ + G + I L+ P T+A
Sbjct: 196 LPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILSTPEGTSA 255
Query: 68 IFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIREST 127
K+ I+ K +DI + + L+++ + G LIGK G +K+I + T
Sbjct: 256 ACKSILEIMHKEAQDIKFT---------EEIPLKILAHNNFVGRLIGKEGRNLKKIEQDT 306
Query: 128 GAQVQVA--GDMLPNSTERAITIAGIPQSIIECVKQICVVMLETL--------------- 170
++ ++ ++ + ER IT+ G ++ + ++I + E+
Sbjct: 307 DTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIP 366
Query: 171 -------------------SQSPPKGVTIPYR--------------PKPSSSPVIFAGGQ 197
+ PP +T PY P S +I GQ
Sbjct: 367 GLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQ 426
Query: 198 -----DRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQ 252
R++ S + + + GPP + QG+
Sbjct: 427 HIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGR----------------- 469
Query: 253 QSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINE 312
+G S EVK L+A + +P+ G +IG+ G +NE
Sbjct: 470 ------IYGKIKEENFVSPKEEVK----LEA-------HIRVPSFAAGRVIGKGGKTVNE 512
Query: 313 IRQMSGAQIKIANPVEGSTDRQVT--ITGSAASISLAQ 348
++ +S A++ + + QV ITG + +AQ
Sbjct: 513 LQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQ 550
Score = 36.2 bits (82), Expect = 0.047
Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 10/127 (7%)
Query: 222 LEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGL 281
L G LE +T++ Y PD ++A QQ+ G G SS G
Sbjct: 139 LNGFQLENFTLKVAYI---PD-----EMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSK 190
Query: 282 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE-GSTDRQVTITGS 340
L +P +G IIG++GA I I + + ++I + G+ ++ +TI +
Sbjct: 191 QKPCDLPLR-LLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITILST 249
Query: 341 AASISLA 347
S A
Sbjct: 250 PEGTSAA 256
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 8/134 (5%)
Query: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPE---RIITLAGPTNAIFKAF 72
+++ + + VG+IIGKKG+ +K++ + A I I+ P+ R++ + GP A FKA
Sbjct: 408 VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQ 467
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
I KL+E+ + + VPAS G +IGKGG + E++ T A+V
Sbjct: 468 GRIYGKLKEENFFGPKEEVK-----LETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVV 522
Query: 133 VAGDMLPNSTERAI 146
V D P+ ++ I
Sbjct: 523 VPRDQTPDENDQVI 536
Score = 56.6 bits (135), Expect = 3e-08
Identities = 75/384 (19%), Positives = 150/384 (39%), Gaps = 98/384 (25%)
Query: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
V + +RLL+ + VG+IIGK+G +++ + +++ ++I++ E+ I++
Sbjct: 194 VDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC 253
Query: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
A MI++ + ++ + T V L+++ + G LIGK G +K++ + T
Sbjct: 254 SSACKMILEIMHKEAKDTKT------ADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTE 307
Query: 129 AQVQVAG--DMLPNSTERAITIAG-------IPQSIIECVKQ------------------ 161
++ ++ D+ + ER IT+ G Q I++ V++
Sbjct: 308 TKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPG 367
Query: 162 --ICVVMLETLSQS----PPKGVT--IPYR---------------PKPSSSPVIFAGGQ- 197
+ V L S S PP VT PY P + +I GQ
Sbjct: 368 LNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQH 427
Query: 198 ----DRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQ 253
R+++ S + P T S + GPP + QG+ KL +
Sbjct: 428 IKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRI------YGKLKE----- 476
Query: 254 SHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEI 313
+ ++G + +H + +P G +IG+ G +NE+
Sbjct: 477 ----------------------ENFFGPKEEVKLETH-IRVPASAAGRVIGKGGKTVNEL 513
Query: 314 RQMSGAQIKIANPVEGSTDRQVTI 337
+ ++ A++ + + QV +
Sbjct: 514 QNLTAAEVVVPRDQTPDENDQVIV 537
Score = 50.1 bits (118), Expect = 3e-06
Identities = 69/289 (23%), Positives = 114/289 (39%), Gaps = 35/289 (12%)
Query: 98 VTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIE 157
+ LRL+VP G++IGK G I+ I + T +++ V + E+AI++ P+
Sbjct: 196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGC-- 253
Query: 158 CVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAG------GQDRYSTGSDSASFPH 211
C ++LE + + T P + F G G++ D+ +
Sbjct: 254 --SSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTET--K 309
Query: 212 TTPSMCLNPDLEGPPLEAYTIQGQYA----IPQPDLTKLHQ--------LAMQQSHFP-M 258
T S + L P T++G Q + K+ + +++Q P +
Sbjct: 310 ITISSLQDLTLYNPE-RTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGL 368
Query: 259 THGNTGFSGIESSS-----PEVKGYWGLDASAQTTSHELT---IPNDLIGCIIGRQGAKI 310
G SS+ V G + Q E+ IP +G IIG++G I
Sbjct: 369 NLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHI 428
Query: 311 NEIRQMSGAQIKIANP-VEGSTDRQVTITGSAASISLAQYLINVRLSSE 358
++ + + A IKIA P S R V ITG + AQ I +L E
Sbjct: 429 KQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 346
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 347 AQYLINVRLSSE 358
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 350
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 351 INVRLSSET 359
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQ 197
P + + I ++ E S V P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-----PQRSVGRIIGRGGE 145
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 346
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 347 AQYLINVRLSSE 358
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 350
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 351 INVRLSSET 359
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQ 197
P + + I ++ E S V P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-----PQRSVGRIIGRGGE 145
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 55.1 bits (131), Expect = 1e-07
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 14/119 (11%)
Query: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI-SEGNCPERIITLAGPTNAIFKAF 72
+ I + + + V IIG++G ++K++R+++GARI++ +E ER++ ++G F
Sbjct: 53 IEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISG--------F 104
Query: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQV 131
+ + K + I +T +T PV+ +L VP G +IG+GG I+ I +++GA++
Sbjct: 105 PVQVCKAKAAIHQILTENT-----PVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKI 158
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Query: 289 SHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISL 346
S +L++P +G IIGR G I I + SGA+I EG+ R + I+G+ ++
Sbjct: 126 SEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAA 185
Query: 347 AQYLINVRLSSE 358
A++LI ++S +
Sbjct: 186 AKHLILEKVSED 197
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Query: 291 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYL 350
E+ +P + + IIGRQGA I ++R+ +GA+I + G +R + I+G + A+
Sbjct: 56 EMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD-ERVLLISGFPVQVCKAKAA 114
Query: 351 INVRLSSET 359
I+ L+ T
Sbjct: 115 IHQILTENT 123
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
Query: 91 TAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAG 150
T + + + VP +IG+ G IK++R+ TGA++ V D ER + I+G
Sbjct: 46 TFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--DTEDVGDERVLLISG 103
Query: 151 IPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQ 197
P + + I ++ E S V P+ S +I GG+
Sbjct: 104 FPVQVCKAKAAIHQILTENTPVSEQLSV-----PQRSVGRIIGRGGE 145
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 11 NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGN-CPERIITLAGPTN 66
N ++ +L + + VG IIG+ GE+++ + + SGA+I SEG R+I ++G
Sbjct: 122 NTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 67 AIFKAFAMIIDKLEED 82
+ A +I++K+ ED
Sbjct: 182 EVAAAKHLILEKVSED 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,498,938
Number of Sequences: 37866
Number of extensions: 691784
Number of successful extensions: 1763
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1365
Number of HSP's gapped (non-prelim): 292
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.