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Search of human proteins with 192447438
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|192447438 protein S, alpha preproprotein [Homo sapiens]
(676 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|192447438 protein S, alpha preproprotein [Homo sapiens] 1393 0.0
gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo sa... 588 e-168
gi|221316735 growth arrest-specific 6 isoform 2 [Homo sapiens] 302 8e-82
gi|221316738 growth arrest-specific 6 isoform 3 [Homo sapiens] 286 3e-77
gi|24430141 fibrillin 1 precursor [Homo sapiens] 127 3e-29
gi|110347437 latent transforming growth factor beta binding prot... 125 1e-28
gi|110347412 latent transforming growth factor beta binding prot... 125 1e-28
gi|110347431 latent transforming growth factor beta binding prot... 125 1e-28
gi|66346695 fibrillin 2 precursor [Homo sapiens] 125 2e-28
gi|4503625 coagulation factor X preproprotein [Homo sapiens] 125 2e-28
gi|56237021 fibrillin 3 precursor [Homo sapiens] 123 6e-28
gi|86788132 EGF-containing fibulin-like extracellular matrix pro... 121 2e-27
gi|86788015 EGF-containing fibulin-like extracellular matrix pro... 121 2e-27
gi|9665262 EGF-containing fibulin-like extracellular matrix prot... 121 2e-27
gi|194328809 latent transforming growth factor beta binding prot... 120 5e-27
gi|18497288 latent transforming growth factor beta binding prote... 120 5e-27
gi|10190748 CEGP1 protein [Homo sapiens] 120 5e-27
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 118 2e-26
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 118 2e-26
gi|19743803 fibulin 5 precursor [Homo sapiens] 116 6e-26
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 115 1e-25
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 115 1e-25
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 115 1e-25
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 115 1e-25
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 115 1e-25
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 114 2e-25
gi|34734066 fibulin 1 isoform D [Homo sapiens] 113 7e-25
gi|7382460 sex hormone-binding globulin isoform 1 precursor [Hom... 107 3e-23
gi|46249414 latent transforming growth factor beta binding prote... 107 5e-23
gi|46249412 latent transforming growth factor beta binding prote... 107 5e-23
>gi|192447438 protein S, alpha preproprotein [Homo sapiens]
Length = 676
Score = 1393 bits (3606), Expect = 0.0
Identities = 676/676 (100%), Positives = 676/676 (100%)
Query: 1 MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIE 60
MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIE
Sbjct: 1 MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIE 60
Query: 61 ELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQ 120
ELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQ
Sbjct: 61 ELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQ 120
Query: 121 CSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPG 180
CSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPG
Sbjct: 121 CSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPG 180
Query: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS 240
SYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS
Sbjct: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS 240
Query: 241 CEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELL 300
CEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELL
Sbjct: 241 CEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELL 300
Query: 301 YLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIE 360
YLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIE
Sbjct: 301 YLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIE 360
Query: 361 VQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGL 420
VQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGL
Sbjct: 361 VQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGL 420
Query: 421 LETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVE 480
LETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVE
Sbjct: 421 LETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVE 480
Query: 481 KGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLV 540
KGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLV
Sbjct: 481 KGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLV 540
Query: 541 DSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDL 600
DSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDL
Sbjct: 541 DSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDL 600
Query: 601 QRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHND 660
QRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHND
Sbjct: 601 QRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHND 660
Query: 661 IRAHSCPSVWKKTKNS 676
IRAHSCPSVWKKTKNS
Sbjct: 661 IRAHSCPSVWKKTKNS 676
>gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo
sapiens]
Length = 678
Score = 588 bits (1515), Expect = e-168
Identities = 297/671 (44%), Positives = 423/671 (63%), Gaps = 28/671 (4%)
Query: 12 LACLLLVLPVSEANFLSKQQASQVL-VRKRRANSLLEETKQGNLERECIEELCNKEEARE 70
L LLL + A L ++A+Q L R+RRA + EE KQG+LEREC+EELC++EEARE
Sbjct: 18 LLLLLLAAECALAALLPAREATQFLRPRQRRAFQVFEEAKQGHLERECVEELCSREEARE 77
Query: 71 VFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDG 130
VFENDPETDYFYP+YL C+ + + + N+ +CV +PDQC+P PC+ G
Sbjct: 78 VFENDPETDYFYPRYLDCINKY------GSPYTKNS--GFATCVQNLPDQCTPNPCDRKG 129
Query: 131 YMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
+C+D +F C CK GW G C+ D+NEC S NGGC QIC N PGS+HCSC +GF
Sbjct: 130 TQACQDLMGNFFCLCKAGWGGRLCDKDVNEC---SQENGGCLQICHNKPGSFHCSCHSGF 186
Query: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN 250
+ S+ + C+D+DEC+ CG A CKN+PG + C C EG+ Y+ + K+C D+DEC +
Sbjct: 187 ELSSDGRTCQDIDECA-DSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVDECLQG 245
Query: 251 MCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGV- 309
C Q+CVN PG YTC+CDG+ G KL+QD +CE + C+P ++ + LYL F+G
Sbjct: 246 RCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCEDILPCVPFSVAKSVKSLYLGRMFSGTP 305
Query: 310 VLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTS 369
V+ L+F+ + +R AEFDFRT+D EG++L+A S W+++ALR G++E+QL+
Sbjct: 306 VIRLRFKRLQPTRLVAEFDFRTFDPEGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVG 365
Query: 370 KITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAG 429
++T+ G VIN+G+W +SVEEL ++ IK+ ++AVM I G LF+PE GL + G
Sbjct: 366 RVTSSGPVINHGMWQTISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLNLTVGG 425
Query: 430 FPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSG 489
P E +L++PINPRLDGC+RSWN + + I+E ++ C E+GS+YPGSG
Sbjct: 426 IPFH-EKDLVQPINPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGSFYPGSG 484
Query: 490 IAQFHIDYN----NVSSAEGWHVNVTLNIRPSTGTGVMLALVSGN-NTVPFAVSLVDSTS 544
A + +DY +V + W V V +IRP+ TGV+ AL + + VP +V+LVD S
Sbjct: 485 FAFYSLDYMRTPLDVGTESTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVALVDYHS 544
Query: 545 E---KSQDILLSVENTVIYRIQALSLCSDQQSH---LEFRVNRNNLELSTPLKIETISHE 598
K Q ++L+VE+T + + + +C D Q H + R LE+ +S
Sbjct: 545 TKKLKKQLVVLAVEHTAL-ALMEIKVC-DGQEHVVTVSLRDGEATLEVDGTRGQSEVSAA 602
Query: 599 DLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKH 658
LQ +LAVL++ +++ V T+ GGLPDVP ++ PV AFY GCM + +N LDLDEA KH
Sbjct: 603 QLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVTAFYRGCMTLEVNRRLLDLDEAAYKH 662
Query: 659 NDIRAHSCPSV 669
+DI AHSCP V
Sbjct: 663 SDITAHSCPPV 673
>gi|221316735 growth arrest-specific 6 isoform 2 [Homo sapiens]
Length = 405
Score = 302 bits (773), Expect = 8e-82
Identities = 163/401 (40%), Positives = 244/401 (60%), Gaps = 15/401 (3%)
Query: 281 SCEVVSVCLPLNLDTKYELLYLAEQFAGV-VLYLKFRLPEISRFSAEFDFRTYDSEGVIL 339
+CE + C+P ++ + LYL F+G V+ L+F+ + +R AEFDFRT+D EG++L
Sbjct: 3 TCEDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLRFKRLQPTRLVAEFDFRTFDPEGILL 62
Query: 340 YAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKI 399
+A S W+++ALR G++E+QL+ ++T+ G VIN+G+W +SVEEL ++ IK+
Sbjct: 63 FAGGHQDSTWIVLALRAGRLELQLRYNGVGRVTSSGPVINHGMWQTISVEELARNLVIKV 122
Query: 400 AKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQG 459
++AVM I G LF+PE GL + G P E +L++PINPRLDGC+RSWN +
Sbjct: 123 NRDAVMKIAVAGDLFQPERGLYHLNLTVGGIPFH-EKDLVQPINPRLDGCMRSWNWLNGE 181
Query: 460 ASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYN----NVSSAEGWHVNVTLNIR 515
+ I+E ++ C E+GS+YPGSG A + +DY +V + W V V +IR
Sbjct: 182 DTTIQETVKVNTRMQCFSVTERGSFYPGSGFAFYSLDYMRTPLDVGTESTWEVEVVAHIR 241
Query: 516 PSTGTGVMLALVSGN-NTVPFAVSLVDSTSE---KSQDILLSVENTVIYRIQALSLCSDQ 571
P+ TGV+ AL + + VP +V+LVD S K Q ++L+VE+T + + + +C D
Sbjct: 242 PAADTGVLFALWAPDLRAVPLSVALVDYHSTKKLKKQLVVLAVEHTAL-ALMEIKVC-DG 299
Query: 572 QSH---LEFRVNRNNLELSTPLKIETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFS 628
Q H + R LE+ +S LQ +LAVL++ +++ V T+ GGLPDVP +
Sbjct: 300 QEHVVTVSLRDGEATLEVDGTRGQSEVSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVT 359
Query: 629 ATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSV 669
+ PV AFY GCM + +N LDLDEA KH+DI AHSCP V
Sbjct: 360 SAPVTAFYRGCMTLEVNRRLLDLDEAAYKHSDITAHSCPPV 400
>gi|221316738 growth arrest-specific 6 isoform 3 [Homo sapiens]
Length = 379
Score = 286 bits (733), Expect = 3e-77
Identities = 156/376 (41%), Positives = 231/376 (61%), Gaps = 15/376 (3%)
Query: 306 FAGV-VLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLK 364
F+G V+ L+F+ + +R AEFDFRT+D EG++L+A S W+++ALR G++E+QL+
Sbjct: 2 FSGTPVIRLRFKRLQPTRLVAEFDFRTFDPEGILLFAGGHQDSTWIVLALRAGRLELQLR 61
Query: 365 NEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETK 424
++T+ G VIN+G+W +SVEEL ++ IK+ ++AVM I G LF+PE GL
Sbjct: 62 YNGVGRVTSSGPVINHGMWQTISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLN 121
Query: 425 VYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSY 484
+ G P E +L++PINPRLDGC+RSWN + + I+E ++ C E+GS+
Sbjct: 122 LTVGGIPFH-EKDLVQPINPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGSF 180
Query: 485 YPGSGIAQFHIDYN----NVSSAEGWHVNVTLNIRPSTGTGVMLALVSGN-NTVPFAVSL 539
YPGSG A + +DY +V + W V V +IRP+ TGV+ AL + + VP +V+L
Sbjct: 181 YPGSGFAFYSLDYMRTPLDVGTESTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVAL 240
Query: 540 VDSTSE---KSQDILLSVENTVIYRIQALSLCSDQQSH---LEFRVNRNNLELSTPLKIE 593
VD S K Q ++L+VE+T + + + +C D Q H + R LE+
Sbjct: 241 VDYHSTKKLKKQLVVLAVEHTAL-ALMEIKVC-DGQEHVVTVSLRDGEATLEVDGTRGQS 298
Query: 594 TISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDE 653
+S LQ +LAVL++ +++ V T+ GGLPDVP ++ PV AFY GCM + +N LDLDE
Sbjct: 299 EVSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVTAFYRGCMTLEVNRRLLDLDE 358
Query: 654 AISKHNDIRAHSCPSV 669
A KH+DI AHSCP V
Sbjct: 359 AAYKHSDITAHSCPPV 374
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 127 bits (320), Expect = 3e-29
Identities = 64/187 (34%), Positives = 98/187 (52%), Gaps = 16/187 (8%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDP 164
P++ +C++ + S C C + + C C PG+ DI+EC
Sbjct: 1148 PNISACIDINECELSAHLCPNG---RCVNLIGKYQCACNPGYHSTPDRLFCVDIDEC--- 1201
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
S +NGGC C N+ GSY CSC+ GF ++ +++ C D+DEC P+IC C NIPG++
Sbjct: 1202 SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEY 1261
Query: 225 ECECPEGYRYNLKSKSCEDIDEC--SENMC-AQLCVNYPGGYTCYCD----GKKGFKLAQ 277
C C +G+ + K+C D++EC + N+C + C N G + C+CD GKKG
Sbjct: 1262 RCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCT 1321
Query: 278 DQKSCEV 284
D CE+
Sbjct: 1322 DINECEI 1328
Score = 122 bits (305), Expect = 1e-27
Identities = 66/162 (40%), Positives = 92/162 (56%), Gaps = 14/162 (8%)
Query: 134 CKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQI--CDNTPGSYHCSCKNG 189
C + SF C+C PGW G+ KC D++EC + +++ CSQ C NT GSY C CK G
Sbjct: 1339 CTNTAGSFKCSCSPGWIGDGIKCT-DLDECSNGTHM---CSQHADCKNTMGSYRCLCKEG 1394
Query: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS- 248
+ + C D+DECS ++CG C N PG + CEC G+ + K+CEDIDECS
Sbjct: 1395 YT--GDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL 1452
Query: 249 ENMCA-QLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL 289
N+C C N PG + C C+ G++L + +C V+ CL
Sbjct: 1453 PNICVFGTCHNLPGLFRCECE--IGYELDRSGGNCTDVNECL 1492
Score = 117 bits (293), Expect = 3e-26
Identities = 63/163 (38%), Positives = 87/163 (53%), Gaps = 17/163 (10%)
Query: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
C + + S+ C CK G+ G C D+NEC C+ IC NT GSY CSC G
Sbjct: 2418 CVNDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPK---PCNFICKNTEGSYQCSCPKG 2473
Query: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE 249
+++ + + CKD+DEC+ K C +C N G F C+CP G+ + SC D +EC+
Sbjct: 2474 YILQEDGRSCKDLDECATKQHNC-QFLCVNTIGGFTCKCPPGFTQH--HTSCIDNNECTS 2530
Query: 250 --NMCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
N+C +C N PG +TC C ++GF L Q SCE V C
Sbjct: 2531 DINLCGSKGICQNTPGSFTCEC--QRGFSLDQTGSSCEDVDEC 2571
Score = 117 bits (292), Expect = 5e-26
Identities = 60/153 (39%), Positives = 82/153 (53%), Gaps = 8/153 (5%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQICD 176
D+CS + CK+ S+ C CK G+ G+ C D++EC + N+ G C
Sbjct: 1365 DECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCT-DLDECSENLNLCGNGQ--CL 1421
Query: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
N PG Y C C GFV ++ K C+D+DECSL P+IC C N+PG F CEC GY +
Sbjct: 1422 NAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNLPGLFRCECEIGYELDR 1480
Query: 237 KSKSCEDIDECSE--NMCAQLCVNYPGGYTCYC 267
+C D++EC + + CVN PG Y C C
Sbjct: 1481 SGGNCTDVNECLDPTTCISGNCVNTPGSYICDC 1513
Score = 112 bits (281), Expect = 9e-25
Identities = 65/186 (34%), Positives = 85/186 (45%), Gaps = 17/186 (9%)
Query: 111 RSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQG-----EKCEFDINEC-KDP 164
R+C + + SP C G C + F C C G++ + C DI+EC +DP
Sbjct: 1066 RNCTDIDECRISPDLC---GRGQCVNTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDP 1121
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
GG +C NT GSY C C G + N C D++EC L +C C N+ G +
Sbjct: 1122 LLCRGG---VCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKY 1178
Query: 225 ECECPEGYRYNLKSKSCEDIDECS--ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+C C GY C DIDECS C C N G Y C C + GF L DQ+SC
Sbjct: 1179 QCACNPGYHSTPDRLFCVDIDECSIMNGGCETFCTNSEGSYECSC--QPGFALMPDQRSC 1236
Query: 283 EVVSVC 288
+ C
Sbjct: 1237 TDIDEC 1242
Score = 112 bits (279), Expect = 1e-24
Identities = 65/198 (32%), Positives = 95/198 (47%), Gaps = 20/198 (10%)
Query: 104 TNAYPDLR--SCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFD 157
T PD+ SCV+ +P PCN CK+ + S+ C+C G+ G C+ D
Sbjct: 2431 TGYTPDITGTSCVDLNECNQAPKPCN----FICKNTEGSYQCSCPKGYILQEDGRSCK-D 2485
Query: 158 INECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGT-AV 216
++EC + C +C NT G + C C GF + C D +EC+ ++CG+ +
Sbjct: 2486 LDECATKQH---NCQFLCVNTIGGFTCKCPPGFTQ--HHTSCIDNNECTSDINLCGSKGI 2540
Query: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN-MCAQLCVNYPGGYTCYCDGKKGFKL 275
C+N PG F CEC G+ + SCED+DEC N C C N GGY C C +G+
Sbjct: 2541 CQNTPGSFTCECQRGFSLDQTGSSCEDVDECEGNHRCQHGCQNIIGGYRCSC--PQGYLQ 2598
Query: 276 AQDQKSCEVVSVCLPLNL 293
C + CL ++
Sbjct: 2599 HYQWNQCVDENECLSAHI 2616
Score = 111 bits (278), Expect = 2e-24
Identities = 62/180 (34%), Positives = 88/180 (48%), Gaps = 22/180 (12%)
Query: 124 LPCNEDGYMS-----CKDGKA-----SFTCTCKPGWQGE---KCEFDINECKDPSNINGG 170
LP N Y C++G+ S C C G+Q + +C D++EC+ G
Sbjct: 445 LPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGEC-IDVDECEKNPCAGGE 503
Query: 171 CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPE 230
C N GSY C C+ G+ + +C+D+DEC IC C N G F C C
Sbjct: 504 CI----NNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNA 559
Query: 231 GYRYNLKSKSCEDIDECS-ENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
G+ K+CED+DECS NMC +C+N G + C C K GF+LA D + C+ ++ C
Sbjct: 560 GFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCIC--KPGFQLASDGRYCKDINEC 617
Score = 111 bits (278), Expect = 2e-24
Identities = 56/157 (35%), Positives = 75/157 (47%), Gaps = 14/157 (8%)
Query: 116 AIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECK-DPSNINGGCSQI 174
A + C P P A + C G DINEC DP G I
Sbjct: 691 AFGEPCQPCPAQNS---------AEYQALCSSGPGMTSAGSDINECALDPDICPNG---I 738
Query: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRY 234
C+N G+Y C C +G+ + S K+C D++EC L +C C+N PG F C CP+G+ Y
Sbjct: 739 CENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIY 798
Query: 235 NLKSKSCEDIDECSENMCAQ-LCVNYPGGYTCYCDGK 270
K+CEDIDEC + C +C N PG + C C +
Sbjct: 799 KPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSE 835
Score = 109 bits (273), Expect = 7e-24
Identities = 57/137 (41%), Positives = 78/137 (56%), Gaps = 10/137 (7%)
Query: 157 DINECKD-PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
DINECK PS G C NT GS+ C C +GF + S +++C D+DEC + P +CG
Sbjct: 1028 DINECKMIPSLCTHGK---CRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRG 1084
Query: 216 VCKNIPGDFECECPEGYRYN-LKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGKK 271
C N PGDFEC+C EGY + K+C DIDEC + +C +C N G Y C C
Sbjct: 1085 QCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCEC--PP 1142
Query: 272 GFKLAQDQKSCEVVSVC 288
G +L+ + +C ++ C
Sbjct: 1143 GHQLSPNISACIDINEC 1159
Score = 107 bits (267), Expect = 4e-23
Identities = 64/187 (34%), Positives = 91/187 (48%), Gaps = 18/187 (9%)
Query: 110 LRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ---GEKCEFDINECKDPSN 166
+++C++ Q PL C C + + S+ C C PG Q DINEC+ ++
Sbjct: 1108 MKNCMDIDECQRDPLLCRGG---VCHNTEGSYRCECPPGHQLSPNISACIDINECELSAH 1164
Query: 167 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
+ NG C N G Y C+C G+ ++ C D+DECS+ C T C N G +
Sbjct: 1165 LCPNGRCV----NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCET-FCTNSEGSY 1219
Query: 225 ECECPEGYRYNLKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKS 281
EC C G+ +SC DIDEC +N +C C N PG Y C C GF ++D K+
Sbjct: 1220 ECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLC--YDGFMASEDMKT 1277
Query: 282 CEVVSVC 288
C V+ C
Sbjct: 1278 CVDVNEC 1284
Score = 106 bits (264), Expect = 8e-23
Identities = 58/166 (34%), Positives = 86/166 (51%), Gaps = 14/166 (8%)
Query: 126 CNED--GYMSCKDGKASFTCTCKPGW---QGEKCEFDINECKDPSNINGGCSQICDNTPG 180
C D G +C++ SF C C G+ C D++EC N N + C NT G
Sbjct: 1895 CERDACGNGTCRNTIGSFNCRCNHGFILSHNNDC-IDVDECAS-GNGNLCRNGQCINTVG 1952
Query: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS 240
S+ C C G+ + + + C D++EC L+P C C+N+ G + C CP G Y+L+++
Sbjct: 1953 SFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPG--YSLQNEK 2010
Query: 241 CEDIDECSE--NMCA-QLCVNYPGGYTCYCDGKKGFKLAQDQKSCE 283
CEDIDEC E +CA C N G + C C +GF L+ + C+
Sbjct: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLC--PEGFSLSSSGRRCQ 2054
Score = 105 bits (263), Expect = 1e-22
Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 12/140 (8%)
Query: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
C++ SFTC C+ G+ G CE D++EC+ N C C N G Y CSC G
Sbjct: 2541 CQNTPGSFTCECQRGFSLDQTGSSCE-DVDECEG----NHRCQHGCQNIIGGYRCSCPQG 2595
Query: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-- 247
++ C D +EC L ICG A C N G ++C CP G++Y S C+DI+EC
Sbjct: 2596 YLQHYQWNQCVDENEC-LSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGS 2654
Query: 248 SENMCAQLCVNYPGGYTCYC 267
++ C+ C N GGY C C
Sbjct: 2655 AQAPCSYGCSNTEGGYLCGC 2674
Score = 104 bits (259), Expect = 3e-22
Identities = 61/168 (36%), Positives = 90/168 (53%), Gaps = 20/168 (11%)
Query: 109 DLRS-CVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE----KCEFDINECKD 163
DLR C++ D+C PC C + + S+TC C+ G+Q +C DI+EC
Sbjct: 483 DLRGECIDV--DECEKNPCAGG---ECINNQGSYTCQCRAGYQSTLTRTECR-DIDECLQ 536
Query: 164 PSNI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIP 221
I NG C NT GS+HC C GF + + K+C+D+DECS++ ++C +C N
Sbjct: 537 NGRICNNGRCI----NTDGSFHCVCNAGFHVTRDGKNCEDMDECSIR-NMCLNGMCINED 591
Query: 222 GDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTCYC 267
G F+C C G++ + C+DI+EC + +C CVN G Y C C
Sbjct: 592 GSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCEC 639
Score = 102 bits (255), Expect = 9e-22
Identities = 74/227 (32%), Positives = 94/227 (41%), Gaps = 53/227 (23%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE---KCEFDINECKDP 164
PD RSC + D+C P DG C + + C C G+ K D+NEC
Sbjct: 1231 PDQRSCTDI--DECEDNPNICDGGQ-CTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLN 1287
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGD 223
NI S C+NT GS+ C C G+ K C D++EC + CG AVC N G
Sbjct: 1288 PNIC--LSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGS 1345
Query: 224 FECECPEG---------------------------------YR------YNLKSKSCEDI 244
F+C C G YR Y +C D+
Sbjct: 1346 FKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDL 1405
Query: 245 DECSE--NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
DECSE N+C C+N PGGY C CD GF + D K+CE + C
Sbjct: 1406 DECSENLNLCGNGQCLNAPGGYRCECD--MGFVPSADGKACEDIDEC 1450
Score = 100 bits (249), Expect = 4e-21
Identities = 59/180 (32%), Positives = 94/180 (52%), Gaps = 20/180 (11%)
Query: 119 DQCSPLP-CNEDGYMSCKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQ- 173
D+C P C + C + S+ C CKPG++ +C D NEC++ NI CS
Sbjct: 1810 DECQNGPVCQRNA--ECINTAGSYRCDCKPGYRFTSTGQCN-DRNECQEIPNI---CSHG 1863
Query: 174 ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYR 233
C +T GS++C C GF ++ C D++EC + CG C+N G F C C G+
Sbjct: 1864 QCIDTVGSFYCLCHTGFKTNDDQTMCLDINEC--ERDACGNGTCRNTIGSFNCRCNHGFI 1921
Query: 234 YNLKSKSCEDIDECSE---NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL 289
+ + C D+DEC+ N+C C+N G + C C+ +G+++A D ++C ++ CL
Sbjct: 1922 LS-HNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCN--EGYEVAPDGRTCVDINECL 1978
Score = 97.1 bits (240), Expect = 5e-20
Identities = 64/179 (35%), Positives = 88/179 (49%), Gaps = 20/179 (11%)
Query: 113 CVNAIPDQCSP-LPCNEDGYMSCKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNIN 168
CV+ D+CS PC G +CK+ F CTC+ G++ CE DINEC +
Sbjct: 2164 CVDT--DECSVGNPC---GNGTCKNVIGGFECTCEEGFEPGPMMTCE-DINECAQNPLL- 2216
Query: 169 GGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC--GTAVCKNIPGDFEC 226
C+ C NT GSY C C G+V+ +++ CKD DEC C CKN+ G + C
Sbjct: 2217 --CAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMC 2274
Query: 227 ECPEGYRYNLKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
C GY+ + C D +EC +C C+N G YTC C+ GF + +Q C
Sbjct: 2275 ICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECN--DGFTASPNQDEC 2331
Score = 89.7 bits (221), Expect = 8e-18
Identities = 50/141 (35%), Positives = 67/141 (47%), Gaps = 16/141 (11%)
Query: 164 PSNINGGCSQI--------CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
P N+ C + C TPGS C C GF L + +C DVDEC P C
Sbjct: 446 PVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGF-QLDLRGECIDVDECEKNP--CAGG 502
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKG 272
C N G + C+C GY+ L C DIDEC +N +C C+N G + C C+ G
Sbjct: 503 ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNA--G 560
Query: 273 FKLAQDQKSCEVVSVCLPLNL 293
F + +D K+CE + C N+
Sbjct: 561 FHVTRDGKNCEDMDECSIRNM 581
Score = 89.7 bits (221), Expect = 8e-18
Identities = 55/174 (31%), Positives = 79/174 (45%), Gaps = 16/174 (9%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ-ICDN 177
+QC P+P ++ C + F G DI+EC++ I G C +C N
Sbjct: 1734 EQC-PIPSTDEFATLCGSQRPGFVIDIYTG-----LPVDIDECRE---IPGVCENGVCIN 1784
Query: 178 TPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLK 237
GS+ C C GF C+D+DEC P A C N G + C+C GYR+
Sbjct: 1785 MVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFT-S 1843
Query: 238 SKSCEDIDECSE--NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
+ C D +EC E N+C+ C++ G + C C GFK DQ C ++ C
Sbjct: 1844 TGQCNDRNECQEIPNICSHGQCIDTVGSFYCLC--HTGFKTNDDQTMCLDINEC 1895
Score = 86.3 bits (212), Expect = 9e-17
Identities = 62/176 (35%), Positives = 84/176 (47%), Gaps = 22/176 (12%)
Query: 119 DQCSPLP--CNEDGYMSCKDGKASFTCTCKPGW-QGEK---CEFDINECKDPSNINGGCS 172
D+C +P C E+G C + SF C C G+ +K CE DI+EC+ NG
Sbjct: 1768 DECREIPGVC-ENGV--CINMVGSFRCECPVGFFYNDKLLVCE-DIDECQ-----NGPVC 1818
Query: 173 QI---CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECP 229
Q C NT GSY C CK G+ S + C D +EC P+IC C + G F C C
Sbjct: 1819 QRNAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCH 1877
Query: 230 EGYRYNLKSKSCEDIDECSENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEV 284
G++ N C DI+EC + C C N G + C C+ GF L+ + +V
Sbjct: 1878 TGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCN--HGFILSHNNDCIDV 1931
Score = 85.9 bits (211), Expect = 1e-16
Identities = 46/131 (35%), Positives = 64/131 (48%), Gaps = 11/131 (8%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECK-DPSNINGGCSQ 173
D+C+ N C + SF C C G++ G C DINEC +P G
Sbjct: 1932 DECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPGT-- 1988
Query: 174 ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYR 233
C N GSY C C G+ + + K C+D+DEC +P IC C N G F+C CPEG+
Sbjct: 1989 -CQNLDGSYRCICPPGYSLQNEK--CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFS 2045
Query: 234 YNLKSKSCEDI 244
+ + C+D+
Sbjct: 2046 LSSSGRRCQDL 2056
Score = 84.0 bits (206), Expect = 4e-16
Identities = 51/153 (33%), Positives = 73/153 (47%), Gaps = 22/153 (14%)
Query: 143 CTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCK 200
C C G W E+CE EC P ++C PG NG K K
Sbjct: 980 CCCSVGAAWGTEECE----EC--PMRNTPEYEELCPRGPGFATKEITNG------KPFFK 1027
Query: 201 DVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC--SENMCAQ-LCV 257
D++EC + PS+C C+N G F+C C G+ + + ++C DIDEC S ++C + CV
Sbjct: 1028 DINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCV 1087
Query: 258 NYPGGYTCYCDG--KKGFKLAQDQKSCEVVSVC 288
N PG + C CD + GF + K+C + C
Sbjct: 1088 NTPGDFECKCDEGYESGFMM---MKNCMDIDEC 1117
Score = 82.4 bits (202), Expect = 1e-15
Identities = 57/184 (30%), Positives = 77/184 (41%), Gaps = 29/184 (15%)
Query: 125 PCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFD---------INECKDPSNING------ 169
P E G ++ A C C G+ G +CE D I+ ++G
Sbjct: 148 PVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKT 207
Query: 170 -GCSQI-------CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIP 221
C+ + C+ P H C+ GF+ C+DVDEC P +C C N
Sbjct: 208 LCCATVGRAWGHPCEMCPAQPH-PCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTV 266
Query: 222 GDFECECPEGYRYNLKSKSCEDIDECS--ENMC-AQLCVNYPGGYTCYCDGKKGFKLAQD 278
G FEC+CP G++ N S+ CEDIDECS +C C N Y C C GF + D
Sbjct: 267 GSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKC--PPGFYTSPD 324
Query: 279 QKSC 282
C
Sbjct: 325 GTRC 328
Score = 76.6 bits (187), Expect = 7e-14
Identities = 62/219 (28%), Positives = 89/219 (40%), Gaps = 51/219 (23%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 167
PD CV+ Q P C E+G C + + S+TC C G+ + +EC D N
Sbjct: 2284 PDGEGCVDENECQTKPGIC-ENG--RCLNTRGSYTCECNDGFTASPNQ---DECLD--NR 2335
Query: 168 NGGC--------SQI--------------CDNTPG-SYHCS-------------CKNGFV 191
G C QI CD G HC C +G
Sbjct: 2336 EGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRG 2395
Query: 192 MLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-- 249
++N D +DEC + +C C N G + C C GY ++ SC D++EC++
Sbjct: 2396 FMTNGAD---IDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAP 2452
Query: 250 NMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
C +C N G Y C C KG+ L +D +SC+ + C
Sbjct: 2453 KPCNFICKNTEGSYQCSC--PKGYILQEDGRSCKDLDEC 2489
Score = 76.3 bits (186), Expect = 9e-14
Identities = 42/115 (36%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Query: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGC-SQICDNTPGSYHCSCKN 188
C + SF C C G+ G+ CE D++EC +I C + +C N GS+ C CK
Sbjct: 546 CINTDGSFHCVCNAGFHVTRDGKNCE-DMDEC----SIRNMCLNGMCINEDGSFKCICKP 600
Query: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
GF + S+ + CKD++EC P IC C N G + CEC G L + C D
Sbjct: 601 GFQLASDGRYCKDINECET-PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVD 654
Score = 70.9 bits (172), Expect = 4e-12
Identities = 73/263 (27%), Positives = 102/263 (38%), Gaps = 94/263 (35%)
Query: 104 TNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDIN 159
T+A D+ C PD C +G C++ + ++ C C G++ G+ C DIN
Sbjct: 718 TSAGSDINECA-LDPDICP------NGI--CENLRGTYKCICNSGYEVDSTGKNC-VDIN 767
Query: 160 ECKDPSNI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSI---C-- 212
EC S + NG C NTPGS+ C+C GF+ + K C+D+DEC P I C
Sbjct: 768 ECVLNSLLCDNGQCR----NTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKN 823
Query: 213 --GTAVCK----------------NIPG-------DFECE-------------------- 227
G+ +C+ I G D CE
Sbjct: 824 SPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAW 883
Query: 228 ------------CPEGYRYNLKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYCDGKKG 272
C +GY +K CEDIDEC +C LCVN G + C C G
Sbjct: 884 GSPCTLCQVDPICGKGYS-RIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQC--PSG 940
Query: 273 FKLAQDQKSCEVVSVCLPLNLDT 295
L + +CL + L+T
Sbjct: 941 MTLDATGR------ICLDIRLET 957
Score = 70.5 bits (171), Expect = 5e-12
Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 39/189 (20%)
Query: 133 SCKDGKASFTCTCKPGWQ----GEKCE----------FDINECKDPSNIN---------- 168
+C + + SF C C G+ G +C+ F+ +C P + N
Sbjct: 2028 TCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCAL 2087
Query: 169 -----GGCSQICDNTPG-SYHCSCKNGFVMLSNKKDCK-DVDECSLKPSICGTAVCKNIP 221
G ++C P ++ C G ++ D D+DEC +P +C C N
Sbjct: 2088 KGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK-EPDVCKHGQCINTD 2146
Query: 222 GDFECECPEGYRYNLKSKSCEDIDECS-ENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQ 279
G + CECP G Y L C D DECS N C C N GG+ C C+ +GF+
Sbjct: 2147 GSYRCECPFG--YILAGNECVDTDECSVGNPCGNGTCKNVIGGFECTCE--EGFE-PGPM 2201
Query: 280 KSCEVVSVC 288
+CE ++ C
Sbjct: 2202 MTCEDINEC 2210
Score = 68.2 bits (165), Expect = 2e-11
Identities = 41/127 (32%), Positives = 56/127 (44%), Gaps = 12/127 (9%)
Query: 157 DINECKD-PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
DI+EC++ P GG C NT GS+ C C G+ + + + C DV+EC P ICG
Sbjct: 1606 DIDECQELPGLCQGGK---CINTFGSFQCRCPTGYYLNEDTRVCDDVNECET-PGICGPG 1661
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKL 275
C N G++ C CP Y +C D M LC CDG+ F +
Sbjct: 1662 TCYNTVGNYTCICPPDYMQVNGGNNCMD-------MRRSLCYRNYYADNQTCDGELLFNM 1714
Query: 276 AQDQKSC 282
+ C
Sbjct: 1715 TKKMCCC 1721
Score = 67.4 bits (163), Expect = 4e-11
Identities = 51/176 (28%), Positives = 70/176 (39%), Gaps = 41/176 (23%)
Query: 102 QSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKD------GKASFTCTCKPGWQGEKCE 155
+S N Y D+R P ++G +C + KAS C+ W G CE
Sbjct: 1530 RSGNCYLDIR-------------PRGDNGDTACSNEIGVGVSKASCCCSLGKAW-GTPCE 1575
Query: 156 FDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC--KDVDECSLKPSICG 213
C + NT Y C G N +D+DEC P +C
Sbjct: 1576 M--------------CPAV--NT-SEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQ 1618
Query: 214 TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTCYC 267
C N G F+C CP GY N ++ C+D++EC + +C C N G YTC C
Sbjct: 1619 GGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCIC 1674
Score = 64.3 bits (155), Expect = 3e-10
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Query: 157 DINECKD-PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
D++EC+ P GG C NT GS+ C C G + + C+D+DECS P IC
Sbjct: 246 DVDECQAIPGLCQGGN---CINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDI 244
C N + C+CP G+ + C D+
Sbjct: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDV 331
Score = 63.5 bits (153), Expect = 6e-10
Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 9/103 (8%)
Query: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
C++ + C+C G+ Q +C D NEC ++I GG S C NT GSY C C G
Sbjct: 2581 CQNIIGGYRCSCPQGYLQHYQWNQC-VDENECLS-AHICGGAS--CHNTLGSYKCMCPAG 2636
Query: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
F C+D++EC + C C N G + C CP GY
Sbjct: 2637 FQYEQFSGGCQDINECGSAQAPCSYG-CSNTEGGYLCGCPPGY 2678
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 115 NAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK----CEFDINECKDPSNINGG 170
N D+ L + G SC + S+ C C G+Q E+ C+ DINEC +
Sbjct: 2603 NQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DINEC---GSAQAP 2658
Query: 171 CSQICDNTPGSYHCSCKNGF 190
CS C NT G Y C C G+
Sbjct: 2659 CSYGCSNTEGGYLCGCPPGY 2678
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 125 bits (314), Expect = 1e-28
Identities = 64/163 (39%), Positives = 87/163 (53%), Gaps = 9/163 (5%)
Query: 106 AYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINEC-KDP 164
A P SC + D+C+ P G +CK+ SF C C G++G CE D++EC ++P
Sbjct: 595 AAPHGASCQDV--DECTQSP-GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP 651
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
G CDNT GS+HC+C GF C+DVDEC+ P C C+N G F
Sbjct: 652 PPCGPGR---CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSF 708
Query: 225 ECECPEGYRYNLKSKSCEDIDECSENMC--AQLCVNYPGGYTC 265
+C CP G++ N CED+DEC ++ Q CVN PG + C
Sbjct: 709 QCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQC 751
Score = 107 bits (267), Expect = 4e-23
Identities = 56/158 (35%), Positives = 81/158 (51%), Gaps = 13/158 (8%)
Query: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
C + +TC C G+ QG +C D++EC+ + C+ C+N+PGS+ C C
Sbjct: 494 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECR---RVPPPCAPGRCENSPGSFRCVCGP 549
Query: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
GF +C DVDEC P C C+N PG F C CP GY+ SC+D+DEC+
Sbjct: 550 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 609
Query: 249 EN--MCAQ-LCVNYPGGYTCYCD-GKKGFKLAQDQKSC 282
++ +C + C N PG + C C G +G +D C
Sbjct: 610 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDEC 647
Score = 106 bits (264), Expect = 8e-23
Identities = 65/182 (35%), Positives = 90/182 (49%), Gaps = 20/182 (10%)
Query: 119 DQCSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCE----FDINECKDPSNI--NGG 170
D+CS PC G+ C + + SF C+C PG++ D+NEC + +G
Sbjct: 769 DECSSGAPPCGPHGH--CTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGE 826
Query: 171 CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPE 230
C NT GS+ C+C G+ C DVDECS + +C + +C N G FEC CP
Sbjct: 827 CL----NTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQSGICTNTDGSFECICPP 881
Query: 231 GYRYNLKSKSCEDIDECSEN---MC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVS 286
G+R SC D+DEC E +C +Q C N PG Y C D G+ A + +C+ V
Sbjct: 882 GHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVD 940
Query: 287 VC 288
C
Sbjct: 941 EC 942
Score = 102 bits (255), Expect = 9e-22
Identities = 67/189 (35%), Positives = 96/189 (50%), Gaps = 22/189 (11%)
Query: 112 SCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQG----EKCEFDINECKDPSNI 167
SC++ D+CS + G + DG SF C C PG + C D++EC++
Sbjct: 850 SCLDV--DECSEEDLCQSGICTNTDG--SFECICPPGHRAGPDLASC-LDVDECRERGPA 904
Query: 168 NGGCSQICDNTPGSYHC--SCKNGFVMLSNKKDCKDVDECS-LKPSICGTAVCKNIPGDF 224
G SQ C+N+PGSY C C G+ + C DVDEC P ICG C+N PG +
Sbjct: 905 LCG-SQRCENSPGSYRCVRDCDPGY-HAGPEGTCDDVDECQEYGPEICGAQRCENTPGSY 962
Query: 225 ECE--CPEGYRYNLKSKSCEDIDEC-SENMCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQ 279
C C GY+ C+D+DEC + + C +C N PG + C CD +G++ A+D
Sbjct: 963 RCTPACDPGYQPT-PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCD--QGYEGARDG 1019
Query: 280 KSCEVVSVC 288
+ C V+ C
Sbjct: 1020 RHCVDVNEC 1028
Score = 100 bits (250), Expect = 3e-21
Identities = 65/176 (36%), Positives = 93/176 (52%), Gaps = 23/176 (13%)
Query: 106 AYPDLRSCVNAIPDQC---SPLPCNEDGYMSCKDGKASFTCT--CKPGWQGEK---CEFD 157
A PDL SC++ D+C P C G C++ S+ C C PG+ C+ D
Sbjct: 885 AGPDLASCLDV--DECRERGPALC---GSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-D 938
Query: 158 INECKDPSNINGGCSQICDNTPGSYHCS--CKNGFVMLSNKKDCKDVDECSLKPSICGT- 214
++EC++ G +Q C+NTPGSY C+ C G+ C+DVDEC + S CG
Sbjct: 939 VDECQEYGPEICG-AQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNR-SFCGAH 995
Query: 215 AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMC-AQLCVNYPGGYTCYC 267
AVC+N+PG F+C C +GY + C D++EC + +C A LC N G + C C
Sbjct: 996 AVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1051
Score = 91.7 bits (226), Expect = 2e-18
Identities = 64/182 (35%), Positives = 90/182 (49%), Gaps = 23/182 (12%)
Query: 119 DQC--SPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
D+C SP PC Y C++ + SF C C G+Q G +CE D++EC++ G
Sbjct: 687 DECARSPPPCT---YGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPG--- 739
Query: 173 QICDNTPGSYHC-SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPE 230
Q C N+PGS+ C +C +G + ++ C DVDECS CG C N G F C C
Sbjct: 740 QECVNSPGSFQCRTCPSGHHL--HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAP 797
Query: 231 GYRY-NLKSKSCEDIDECSE-NMCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVS 286
GYR + + C D++EC E + C C+N G + C C G++ SC V
Sbjct: 798 GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC--APGYRPGPRGASCLDVD 855
Query: 287 VC 288
C
Sbjct: 856 EC 857
Score = 84.7 bits (208), Expect = 2e-16
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 8/116 (6%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCT--CKPGWQ---GEKCEFDINECKDPSNINGGCSQ 173
D+C G C++ S+ CT C PG+Q G C+ D++EC++ S G
Sbjct: 940 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFC--GAHA 996
Query: 174 ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECP 229
+C N PGS+ C C G+ + + C DV+EC +CG A+C+N+ G F C CP
Sbjct: 997 VCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1052
Score = 63.9 bits (154), Expect = 5e-10
Identities = 47/161 (29%), Positives = 61/161 (37%), Gaps = 32/161 (19%)
Query: 116 AIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQIC 175
A PD C + + C CT GW G C Q C
Sbjct: 1121 AAPDACDNILARNVTWQEC-------CCTVGEGW-GSGCRI----------------QQC 1156
Query: 176 DNTP-GSYHCSCKNGFVMLSNKKDC---KDVDECSL-KPSICGTAVCKNIPGDFECECPE 230
T Y C +G L+ D +DVDEC L + +C + VC N + C C
Sbjct: 1157 PGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSN 1216
Query: 231 GYRYNLKSKSCEDIDECSENMCA---QLCVNYPGGYTCYCD 268
GY Y+ + C D DEC++ A CVN G Y C C+
Sbjct: 1217 GYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE 1257
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 5/87 (5%)
Query: 205 CSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQ-LCVNYPG 261
C P +CG C + P + C C G+R + + C D+DEC CA C N PG
Sbjct: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
Query: 262 GYTCYCDGKKGFKLAQDQKSCEVVSVC 288
+ C C GF+ C V C
Sbjct: 542 SFRCVCG--PGFRAGPRAAECLDVDEC 566
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 9/98 (9%)
Query: 172 SQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECP-- 229
S +C NT Y C C NG+ + + +C D DEC+ + C C N G + C C
Sbjct: 1200 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1259
Query: 230 ---EGYRYNLKSKSCEDIDE----CSENMCAQLCVNYP 260
+G + S + +D+ C + + A L ++P
Sbjct: 1260 LVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHP 1297
Score = 50.8 bits (120), Expect = 4e-06
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 201 DVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQ------ 254
+ +EC + C C +P F C C +GYR ++ +C DI+EC E A
Sbjct: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
Query: 255 LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
C+N G + C C + GF C
Sbjct: 1525 RCLNTDGSFRCIC--RPGFAPTHQPHHC 1550
Score = 43.5 bits (101), Expect = 6e-04
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 8/82 (9%)
Query: 155 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPS--- 210
E + EC I GC+ C P + C C +G+ + + C D++EC +
Sbjct: 1464 ELEAEEC----GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP 1519
Query: 211 ICGTAVCKNIPGDFECECPEGY 232
+C A C N G F C C G+
Sbjct: 1520 LCVNARCLNTDGSFRCICRPGF 1541
Score = 43.1 bits (100), Expect = 8e-04
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 202 VDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQL--CVNY 259
V +C L G + + P + CP G+ + SCED+DEC+ Q C N
Sbjct: 254 VHDCQLCSERLGNSERVSAP---DGPCPTGFER--VNGSCEDVDECATGGRCQHGECANT 308
Query: 260 PGGYTCYCDGKKGFKLAQDQKSC 282
GGYTC C GF L + SC
Sbjct: 309 RGGYTCVC--PDGFLLDSSRSSC 329
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 134 CKDGKASFTCTCKPGWQGEK----CEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
C++ SF C C G++G + C D+NEC+ + G +C+N GS+ C C N
Sbjct: 998 CQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAA--LCENVEGSFLCVCPN 1053
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 10/102 (9%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMS-CKDGKA-----SFTCTCKPGWQGEKCEF---DI 158
P+ S ++ + L E G + C +G+ FTC C G++ + DI
Sbjct: 1449 PEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1508
Query: 159 NECKDPSNINGGCSQI-CDNTPGSYHCSCKNGFVMLSNKKDC 199
NEC + + C C NT GS+ C C+ GF C
Sbjct: 1509 NECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
Score = 40.0 bits (92), Expect = 0.007
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSC 241
C GF ++ C+DVDEC+ C C N G + C CP+G+ + SC
Sbjct: 277 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
Score = 35.0 bits (79), Expect = 0.23
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 6/57 (10%)
Query: 145 CKPGWQ--GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 199
C G++ CE D++EC G C NT G Y C C +GF++ S++ C
Sbjct: 277 CPTGFERVNGSCE-DVDECATGGRCQHG---ECANTRGGYTCVCPDGFLLDSSRSSC 329
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 125 bits (314), Expect = 1e-28
Identities = 64/163 (39%), Positives = 87/163 (53%), Gaps = 9/163 (5%)
Query: 106 AYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINEC-KDP 164
A P SC + D+C+ P G +CK+ SF C C G++G CE D++EC ++P
Sbjct: 625 AAPHGASCQDV--DECTQSP-GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP 681
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
G CDNT GS+HC+C GF C+DVDEC+ P C C+N G F
Sbjct: 682 PPCGPGR---CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSF 738
Query: 225 ECECPEGYRYNLKSKSCEDIDECSENMC--AQLCVNYPGGYTC 265
+C CP G++ N CED+DEC ++ Q CVN PG + C
Sbjct: 739 QCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQC 781
Score = 107 bits (267), Expect = 4e-23
Identities = 56/158 (35%), Positives = 81/158 (51%), Gaps = 13/158 (8%)
Query: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
C + +TC C G+ QG +C D++EC+ + C+ C+N+PGS+ C C
Sbjct: 524 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECR---RVPPPCAPGRCENSPGSFRCVCGP 579
Query: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
GF +C DVDEC P C C+N PG F C CP GY+ SC+D+DEC+
Sbjct: 580 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 639
Query: 249 EN--MCAQ-LCVNYPGGYTCYCD-GKKGFKLAQDQKSC 282
++ +C + C N PG + C C G +G +D C
Sbjct: 640 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDEC 677
Score = 106 bits (264), Expect = 8e-23
Identities = 65/182 (35%), Positives = 90/182 (49%), Gaps = 20/182 (10%)
Query: 119 DQCSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCE----FDINECKDPSNI--NGG 170
D+CS PC G+ C + + SF C+C PG++ D+NEC + +G
Sbjct: 799 DECSSGAPPCGPHGH--CTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGE 856
Query: 171 CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPE 230
C NT GS+ C+C G+ C DVDECS + +C + +C N G FEC CP
Sbjct: 857 CL----NTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQSGICTNTDGSFECICPP 911
Query: 231 GYRYNLKSKSCEDIDECSEN---MC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVS 286
G+R SC D+DEC E +C +Q C N PG Y C D G+ A + +C+ V
Sbjct: 912 GHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVD 970
Query: 287 VC 288
C
Sbjct: 971 EC 972
Score = 102 bits (255), Expect = 9e-22
Identities = 67/189 (35%), Positives = 96/189 (50%), Gaps = 22/189 (11%)
Query: 112 SCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQG----EKCEFDINECKDPSNI 167
SC++ D+CS + G + DG SF C C PG + C D++EC++
Sbjct: 880 SCLDV--DECSEEDLCQSGICTNTDG--SFECICPPGHRAGPDLASC-LDVDECRERGPA 934
Query: 168 NGGCSQICDNTPGSYHC--SCKNGFVMLSNKKDCKDVDECS-LKPSICGTAVCKNIPGDF 224
G SQ C+N+PGSY C C G+ + C DVDEC P ICG C+N PG +
Sbjct: 935 LCG-SQRCENSPGSYRCVRDCDPGY-HAGPEGTCDDVDECQEYGPEICGAQRCENTPGSY 992
Query: 225 ECE--CPEGYRYNLKSKSCEDIDEC-SENMCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQ 279
C C GY+ C+D+DEC + + C +C N PG + C CD +G++ A+D
Sbjct: 993 RCTPACDPGYQPT-PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCD--QGYEGARDG 1049
Query: 280 KSCEVVSVC 288
+ C V+ C
Sbjct: 1050 RHCVDVNEC 1058
Score = 100 bits (250), Expect = 3e-21
Identities = 65/176 (36%), Positives = 93/176 (52%), Gaps = 23/176 (13%)
Query: 106 AYPDLRSCVNAIPDQC---SPLPCNEDGYMSCKDGKASFTCT--CKPGWQGEK---CEFD 157
A PDL SC++ D+C P C G C++ S+ C C PG+ C+ D
Sbjct: 915 AGPDLASCLDV--DECRERGPALC---GSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-D 968
Query: 158 INECKDPSNINGGCSQICDNTPGSYHCS--CKNGFVMLSNKKDCKDVDECSLKPSICGT- 214
++EC++ G +Q C+NTPGSY C+ C G+ C+DVDEC + S CG
Sbjct: 969 VDECQEYGPEICG-AQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNR-SFCGAH 1025
Query: 215 AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMC-AQLCVNYPGGYTCYC 267
AVC+N+PG F+C C +GY + C D++EC + +C A LC N G + C C
Sbjct: 1026 AVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1081
Score = 91.7 bits (226), Expect = 2e-18
Identities = 64/182 (35%), Positives = 90/182 (49%), Gaps = 23/182 (12%)
Query: 119 DQC--SPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
D+C SP PC Y C++ + SF C C G+Q G +CE D++EC++ G
Sbjct: 717 DECARSPPPCT---YGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPG--- 769
Query: 173 QICDNTPGSYHC-SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPE 230
Q C N+PGS+ C +C +G + ++ C DVDECS CG C N G F C C
Sbjct: 770 QECVNSPGSFQCRTCPSGHHL--HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAP 827
Query: 231 GYRY-NLKSKSCEDIDECSE-NMCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVS 286
GYR + + C D++EC E + C C+N G + C C G++ SC V
Sbjct: 828 GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC--APGYRPGPRGASCLDVD 885
Query: 287 VC 288
C
Sbjct: 886 EC 887
Score = 84.7 bits (208), Expect = 2e-16
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 8/116 (6%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCT--CKPGWQ---GEKCEFDINECKDPSNINGGCSQ 173
D+C G C++ S+ CT C PG+Q G C+ D++EC++ S G
Sbjct: 970 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFC--GAHA 1026
Query: 174 ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECP 229
+C N PGS+ C C G+ + + C DV+EC +CG A+C+N+ G F C CP
Sbjct: 1027 VCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1082
Score = 63.9 bits (154), Expect = 5e-10
Identities = 47/161 (29%), Positives = 61/161 (37%), Gaps = 32/161 (19%)
Query: 116 AIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQIC 175
A PD C + + C CT GW G C Q C
Sbjct: 1151 AAPDACDNILARNVTWQEC-------CCTVGEGW-GSGCRI----------------QQC 1186
Query: 176 DNTP-GSYHCSCKNGFVMLSNKKDC---KDVDECSL-KPSICGTAVCKNIPGDFECECPE 230
T Y C +G L+ D +DVDEC L + +C + VC N + C C
Sbjct: 1187 PGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSN 1246
Query: 231 GYRYNLKSKSCEDIDECSENMCA---QLCVNYPGGYTCYCD 268
GY Y+ + C D DEC++ A CVN G Y C C+
Sbjct: 1247 GYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE 1287
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 5/87 (5%)
Query: 205 CSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQ-LCVNYPG 261
C P +CG C + P + C C G+R + + C D+DEC CA C N PG
Sbjct: 512 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 571
Query: 262 GYTCYCDGKKGFKLAQDQKSCEVVSVC 288
+ C C GF+ C V C
Sbjct: 572 SFRCVCG--PGFRAGPRAAECLDVDEC 596
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 9/98 (9%)
Query: 172 SQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECP-- 229
S +C NT Y C C NG+ + + +C D DEC+ + C C N G + C C
Sbjct: 1230 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1289
Query: 230 ---EGYRYNLKSKSCEDIDE----CSENMCAQLCVNYP 260
+G + S + +D+ C + + A L ++P
Sbjct: 1290 LVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHP 1327
Score = 50.8 bits (120), Expect = 4e-06
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 201 DVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQ------ 254
+ +EC + C C +P F C C +GYR ++ +C DI+EC E A
Sbjct: 1496 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1554
Query: 255 LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
C+N G + C C + GF C
Sbjct: 1555 RCLNTDGSFRCIC--RPGFAPTHQPHHC 1580
Score = 43.5 bits (101), Expect = 6e-04
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 8/82 (9%)
Query: 155 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPS--- 210
E + EC I GC+ C P + C C +G+ + + C D++EC +
Sbjct: 1494 ELEAEEC----GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP 1549
Query: 211 ICGTAVCKNIPGDFECECPEGY 232
+C A C N G F C C G+
Sbjct: 1550 LCVNARCLNTDGSFRCICRPGF 1571
Score = 43.1 bits (100), Expect = 8e-04
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 202 VDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQL--CVNY 259
V +C L G + + P + CP G+ + SCED+DEC+ Q C N
Sbjct: 284 VHDCQLCSERLGNSERVSAP---DGPCPTGFER--VNGSCEDVDECATGGRCQHGECANT 338
Query: 260 PGGYTCYCDGKKGFKLAQDQKSC 282
GGYTC C GF L + SC
Sbjct: 339 RGGYTCVC--PDGFLLDSSRSSC 359
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 134 CKDGKASFTCTCKPGWQGEK----CEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
C++ SF C C G++G + C D+NEC+ + G +C+N GS+ C C N
Sbjct: 1028 CQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAA--LCENVEGSFLCVCPN 1083
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 10/102 (9%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMS-CKDGKA-----SFTCTCKPGWQGEKCEF---DI 158
P+ S ++ + L E G + C +G+ FTC C G++ + DI
Sbjct: 1479 PEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1538
Query: 159 NECKDPSNINGGCSQI-CDNTPGSYHCSCKNGFVMLSNKKDC 199
NEC + + C C NT GS+ C C+ GF C
Sbjct: 1539 NECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1580
Score = 40.0 bits (92), Expect = 0.007
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSC 241
C GF ++ C+DVDEC+ C C N G + C CP+G+ + SC
Sbjct: 307 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSC 359
Score = 35.0 bits (79), Expect = 0.23
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 6/57 (10%)
Query: 145 CKPGWQ--GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 199
C G++ CE D++EC G C NT G Y C C +GF++ S++ C
Sbjct: 307 CPTGFERVNGSCE-DVDECATGGRCQHG---ECANTRGGYTCVCPDGFLLDSSRSSC 359
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 125 bits (314), Expect = 1e-28
Identities = 64/163 (39%), Positives = 87/163 (53%), Gaps = 9/163 (5%)
Query: 106 AYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINEC-KDP 164
A P SC + D+C+ P G +CK+ SF C C G++G CE D++EC ++P
Sbjct: 662 AAPHGASCQDV--DECTQSP-GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEP 718
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
G CDNT GS+HC+C GF C+DVDEC+ P C C+N G F
Sbjct: 719 PPCGPGR---CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSF 775
Query: 225 ECECPEGYRYNLKSKSCEDIDECSENMC--AQLCVNYPGGYTC 265
+C CP G++ N CED+DEC ++ Q CVN PG + C
Sbjct: 776 QCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQC 818
Score = 107 bits (267), Expect = 4e-23
Identities = 56/158 (35%), Positives = 81/158 (51%), Gaps = 13/158 (8%)
Query: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
C + +TC C G+ QG +C D++EC+ + C+ C+N+PGS+ C C
Sbjct: 561 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECR---RVPPPCAPGRCENSPGSFRCVCGP 616
Query: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
GF +C DVDEC P C C+N PG F C CP GY+ SC+D+DEC+
Sbjct: 617 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 676
Query: 249 EN--MCAQ-LCVNYPGGYTCYCD-GKKGFKLAQDQKSC 282
++ +C + C N PG + C C G +G +D C
Sbjct: 677 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDEC 714
Score = 106 bits (264), Expect = 8e-23
Identities = 65/182 (35%), Positives = 90/182 (49%), Gaps = 20/182 (10%)
Query: 119 DQCSP--LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCE----FDINECKDPSNI--NGG 170
D+CS PC G+ C + + SF C+C PG++ D+NEC + +G
Sbjct: 836 DECSSGAPPCGPHGH--CTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGE 893
Query: 171 CSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPE 230
C NT GS+ C+C G+ C DVDECS + +C + +C N G FEC CP
Sbjct: 894 CL----NTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQSGICTNTDGSFECICPP 948
Query: 231 GYRYNLKSKSCEDIDECSEN---MC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVS 286
G+R SC D+DEC E +C +Q C N PG Y C D G+ A + +C+ V
Sbjct: 949 GHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVD 1007
Query: 287 VC 288
C
Sbjct: 1008 EC 1009
Score = 102 bits (255), Expect = 9e-22
Identities = 67/189 (35%), Positives = 96/189 (50%), Gaps = 22/189 (11%)
Query: 112 SCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQG----EKCEFDINECKDPSNI 167
SC++ D+CS + G + DG SF C C PG + C D++EC++
Sbjct: 917 SCLDV--DECSEEDLCQSGICTNTDG--SFECICPPGHRAGPDLASC-LDVDECRERGPA 971
Query: 168 NGGCSQICDNTPGSYHC--SCKNGFVMLSNKKDCKDVDECS-LKPSICGTAVCKNIPGDF 224
G SQ C+N+PGSY C C G+ + C DVDEC P ICG C+N PG +
Sbjct: 972 LCG-SQRCENSPGSYRCVRDCDPGY-HAGPEGTCDDVDECQEYGPEICGAQRCENTPGSY 1029
Query: 225 ECE--CPEGYRYNLKSKSCEDIDEC-SENMCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQ 279
C C GY+ C+D+DEC + + C +C N PG + C CD +G++ A+D
Sbjct: 1030 RCTPACDPGYQPT-PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCD--QGYEGARDG 1086
Query: 280 KSCEVVSVC 288
+ C V+ C
Sbjct: 1087 RHCVDVNEC 1095
Score = 100 bits (250), Expect = 3e-21
Identities = 65/176 (36%), Positives = 93/176 (52%), Gaps = 23/176 (13%)
Query: 106 AYPDLRSCVNAIPDQC---SPLPCNEDGYMSCKDGKASFTCT--CKPGWQGEK---CEFD 157
A PDL SC++ D+C P C G C++ S+ C C PG+ C+ D
Sbjct: 952 AGPDLASCLDV--DECRERGPALC---GSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-D 1005
Query: 158 INECKDPSNINGGCSQICDNTPGSYHCS--CKNGFVMLSNKKDCKDVDECSLKPSICGT- 214
++EC++ G +Q C+NTPGSY C+ C G+ C+DVDEC + S CG
Sbjct: 1006 VDECQEYGPEICG-AQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNR-SFCGAH 1062
Query: 215 AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMC-AQLCVNYPGGYTCYC 267
AVC+N+PG F+C C +GY + C D++EC + +C A LC N G + C C
Sbjct: 1063 AVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC 1118
Score = 91.7 bits (226), Expect = 2e-18
Identities = 64/182 (35%), Positives = 90/182 (49%), Gaps = 23/182 (12%)
Query: 119 DQC--SPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCS 172
D+C SP PC Y C++ + SF C C G+Q G +CE D++EC++ G
Sbjct: 754 DECARSPPPCT---YGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPG--- 806
Query: 173 QICDNTPGSYHC-SCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFECECPE 230
Q C N+PGS+ C +C +G + ++ C DVDECS CG C N G F C C
Sbjct: 807 QECVNSPGSFQCRTCPSGHHL--HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAP 864
Query: 231 GYRY-NLKSKSCEDIDECSE-NMCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVS 286
GYR + + C D++EC E + C C+N G + C C G++ SC V
Sbjct: 865 GYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC--APGYRPGPRGASCLDVD 922
Query: 287 VC 288
C
Sbjct: 923 EC 924
Score = 84.7 bits (208), Expect = 2e-16
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 8/116 (6%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCT--CKPGWQ---GEKCEFDINECKDPSNINGGCSQ 173
D+C G C++ S+ CT C PG+Q G C+ D++EC++ S G
Sbjct: 1007 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFC--GAHA 1063
Query: 174 ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECP 229
+C N PGS+ C C G+ + + C DV+EC +CG A+C+N+ G F C CP
Sbjct: 1064 VCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP 1119
Score = 63.9 bits (154), Expect = 5e-10
Identities = 47/161 (29%), Positives = 61/161 (37%), Gaps = 32/161 (19%)
Query: 116 AIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQIC 175
A PD C + + C CT GW G C Q C
Sbjct: 1188 AAPDACDNILARNVTWQEC-------CCTVGEGW-GSGCRI----------------QQC 1223
Query: 176 DNTP-GSYHCSCKNGFVMLSNKKDC---KDVDECSL-KPSICGTAVCKNIPGDFECECPE 230
T Y C +G L+ D +DVDEC L + +C + VC N + C C
Sbjct: 1224 PGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSN 1283
Query: 231 GYRYNLKSKSCEDIDECSENMCA---QLCVNYPGGYTCYCD 268
GY Y+ + C D DEC++ A CVN G Y C C+
Sbjct: 1284 GYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE 1324
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 5/87 (5%)
Query: 205 CSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQ-LCVNYPG 261
C P +CG C + P + C C G+R + + C D+DEC CA C N PG
Sbjct: 549 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 608
Query: 262 GYTCYCDGKKGFKLAQDQKSCEVVSVC 288
+ C C GF+ C V C
Sbjct: 609 SFRCVCG--PGFRAGPRAAECLDVDEC 633
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 9/98 (9%)
Query: 172 SQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECP-- 229
S +C NT Y C C NG+ + + +C D DEC+ + C C N G + C C
Sbjct: 1267 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1326
Query: 230 ---EGYRYNLKSKSCEDIDE----CSENMCAQLCVNYP 260
+G + S + +D+ C + + A L ++P
Sbjct: 1327 LVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHP 1364
Score = 50.8 bits (120), Expect = 4e-06
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 201 DVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQ------ 254
+ +EC + C C +P F C C +GYR ++ +C DI+EC E A
Sbjct: 1533 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1591
Query: 255 LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
C+N G + C C + GF C
Sbjct: 1592 RCLNTDGSFRCIC--RPGFAPTHQPHHC 1617
Score = 43.5 bits (101), Expect = 6e-04
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 8/82 (9%)
Query: 155 EFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPS--- 210
E + EC I GC+ C P + C C +G+ + + C D++EC +
Sbjct: 1531 ELEAEEC----GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP 1586
Query: 211 ICGTAVCKNIPGDFECECPEGY 232
+C A C N G F C C G+
Sbjct: 1587 LCVNARCLNTDGSFRCICRPGF 1608
Score = 43.1 bits (100), Expect = 8e-04
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 202 VDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQL--CVNY 259
V +C L G + + P + CP G+ + SCED+DEC+ Q C N
Sbjct: 321 VHDCQLCSERLGNSERVSAP---DGPCPTGFER--VNGSCEDVDECATGGRCQHGECANT 375
Query: 260 PGGYTCYCDGKKGFKLAQDQKSC 282
GGYTC C GF L + SC
Sbjct: 376 RGGYTCVC--PDGFLLDSSRSSC 396
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 134 CKDGKASFTCTCKPGWQGEK----CEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
C++ SF C C G++G + C D+NEC+ + G +C+N GS+ C C N
Sbjct: 1065 CQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAA--LCENVEGSFLCVCPN 1120
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 10/102 (9%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMS-CKDGKA-----SFTCTCKPGWQGEKCEF---DI 158
P+ S ++ + L E G + C +G+ FTC C G++ + DI
Sbjct: 1516 PEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDI 1575
Query: 159 NECKDPSNINGGCSQI-CDNTPGSYHCSCKNGFVMLSNKKDC 199
NEC + + C C NT GS+ C C+ GF C
Sbjct: 1576 NECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1617
Score = 40.0 bits (92), Expect = 0.007
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSC 241
C GF ++ C+DVDEC+ C C N G + C CP+G+ + SC
Sbjct: 344 CPTGFERVNGS--CEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSC 396
Score = 35.0 bits (79), Expect = 0.23
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 6/57 (10%)
Query: 145 CKPGWQ--GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC 199
C G++ CE D++EC G C NT G Y C C +GF++ S++ C
Sbjct: 344 CPTGFERVNGSCE-DVDECATGGRCQHG---ECANTRGGYTCVCPDGFLLDSSRSSC 396
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 125 bits (313), Expect = 2e-28
Identities = 72/181 (39%), Positives = 98/181 (54%), Gaps = 15/181 (8%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCS--QI 174
D+C N D + SC + SF C+C+ GW G KC D++EC SN CS
Sbjct: 1369 DECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDEC---SNGTHQCSINAQ 1424
Query: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRY 234
C NTPGSY C+C GF + C DVDEC+ ++C C N+PG + CEC G+
Sbjct: 1425 CVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTP 1482
Query: 235 NLKSKSCEDIDECS-ENMCA-QLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL-PL 291
S+SC+DIDECS +N+C C N PG + C CD G++L + +C + C P+
Sbjct: 1483 ASDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICD--DGYELDRTGGNCTDIDECADPI 1540
Query: 292 N 292
N
Sbjct: 1541 N 1541
Score = 121 bits (303), Expect = 2e-27
Identities = 60/167 (35%), Positives = 90/167 (53%), Gaps = 20/167 (11%)
Query: 134 CKDGKA-----SFTCTCKPGWQG----EKCEFDINECKDPSNINGGCSQICDNTPGSYHC 184
C++GK ++ C+C PG+Q + C DI+EC +NGGC C N+ GSY C
Sbjct: 1211 CRNGKCVNMIGTYQCSCNPGYQATPDRQGCT-DIDECMI---MNGGCDTQCTNSEGSYEC 1266
Query: 185 SCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDI 244
SC G+ ++ + + C D+DEC P IC C NIPG++ C C +G+ ++ K+C D+
Sbjct: 1267 SCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDV 1326
Query: 245 DEC--SENMCA-QLCVNYPGGYTCYC----DGKKGFKLAQDQKSCEV 284
+EC + N+C C N G + C+C KKG D CE+
Sbjct: 1327 NECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEI 1373
Score = 114 bits (285), Expect = 3e-25
Identities = 63/165 (38%), Positives = 85/165 (51%), Gaps = 20/165 (12%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSN 166
DL C N QCS C + S+ C C G+ G+ C D++EC + N
Sbjct: 1408 DLDECSNGT-HQCSI-------NAQCVNTPGSYRCACSEGFTGDGFTCS-DVDECAENIN 1458
Query: 167 I--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
+ NG C N PG+Y C C+ GF S+ + C+D+DECS + +IC C N+PG F
Sbjct: 1459 LCENGQCL----NVPGAYRCECEMGFTPASDSRSCQDIDECSFQ-NICVFGTCNNLPGMF 1513
Query: 225 ECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCVNYPGGYTCYC 267
C C +GY + +C DIDEC++ N LCVN PG Y C C
Sbjct: 1514 HCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNC 1558
Score = 112 bits (279), Expect = 1e-24
Identities = 56/137 (40%), Positives = 78/137 (56%), Gaps = 10/137 (7%)
Query: 157 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
DINECK G C+ C NT GS+ C C +GF + +++C D+DEC + P +CG+
Sbjct: 1073 DINECKA---FPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSG 1129
Query: 216 VCKNIPGDFECECPEGYRYN-LKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGKK 271
+C N PG FECEC EGY + K+C DIDEC N +C CVN G + C C
Sbjct: 1130 ICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDC--PL 1187
Query: 272 GFKLAQDQKSCEVVSVC 288
G +L+ ++ C ++ C
Sbjct: 1188 GHELSPSREDCVDINEC 1204
Score = 111 bits (277), Expect = 2e-24
Identities = 65/194 (33%), Positives = 83/194 (42%), Gaps = 50/194 (25%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQI 174
D+C +P N C + SF C CK G+ G C D++EC C+ I
Sbjct: 2451 DECKVMP-NLCTNGQCINTMGSFRCFCKVGYTTDISGTSC-IDLDECSQSPK---PCNYI 2505
Query: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLK-------------------------- 208
C NT GSY CSC G+V+ + K CKD+DEC K
Sbjct: 2506 CKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQH 2565
Query: 209 -------------PSICGT-AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN-MCA 253
PS+CG +C+N PG F CEC G+ + +CED+DEC N C
Sbjct: 2566 HTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQ 2625
Query: 254 QLCVNYPGGYTCYC 267
C N GGY C C
Sbjct: 2626 HGCQNILGGYRCGC 2639
Score = 110 bits (276), Expect = 3e-24
Identities = 66/184 (35%), Positives = 92/184 (50%), Gaps = 19/184 (10%)
Query: 106 AYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ---GEKCEFDINECK 162
A D C++ D+C PC G +CK+ S+ C C PG++ C DI+EC
Sbjct: 1925 ASQDQTMCMDV--DECERHPC---GNGTCKNTVGSYNCLCYPGFELTHNNDC-LDIDECS 1978
Query: 163 DPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIP 221
S C C N GS+ C C G+ + + K+C D +EC P C C+N+
Sbjct: 1979 --SFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLE 2036
Query: 222 GDFECECPEGYRYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGYTCYCDGKKGFKLAQD 278
G F C CP G Y +KS++C DI+EC E N+C C N PGG+ C C GF L+ +
Sbjct: 2037 GSFRCICPPG--YEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLC--PPGFVLSDN 2092
Query: 279 QKSC 282
+ C
Sbjct: 2093 GRRC 2096
Score = 109 bits (272), Expect = 9e-24
Identities = 62/186 (33%), Positives = 90/186 (48%), Gaps = 17/186 (9%)
Query: 111 RSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQG-----EKCEFDINEC-KDP 164
R+C + + SP C G C + SF C C G++ + C DI+EC ++P
Sbjct: 1111 RNCTDIDECRISPDLC---GSGICVNTPGSFECECFEGYESGFMMMKNC-MDIDECERNP 1166
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
GG C NT GS+ C C G + +++DC D++ECSL ++C C N+ G +
Sbjct: 1167 LLCRGGT---CVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTY 1223
Query: 225 ECECPEGYRYNLKSKSCEDIDEC--SENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+C C GY+ + C DIDEC C C N G Y C C +G+ L D +SC
Sbjct: 1224 QCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSC--SEGYALMPDGRSC 1281
Query: 283 EVVSVC 288
+ C
Sbjct: 1282 ADIDEC 1287
Score = 107 bits (268), Expect = 3e-23
Identities = 58/160 (36%), Positives = 78/160 (48%), Gaps = 12/160 (7%)
Query: 134 CKDGKASFTCTCKPGWQGEK---CEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
C +S+ C C G++ + C D++EC NG C NTPGSY+C C GF
Sbjct: 510 CIPTVSSYRCECNMGYKQDANGDC-IDVDECTSNPCTNGDCV----NTPGSYYCKCHAGF 564
Query: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SE 249
K+ C D+DEC +C C N G F+C C G+ K+C D DEC +
Sbjct: 565 QRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTT 624
Query: 250 NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
NMC +C+N G + C C K GF LA + + C V C
Sbjct: 625 NMCLNGMCINEDGSFKCIC--KPGFVLAPNGRYCTDVDEC 662
Score = 107 bits (266), Expect = 5e-23
Identities = 56/162 (34%), Positives = 80/162 (49%), Gaps = 14/162 (8%)
Query: 112 SCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNI 167
+C++ P C G C++ SF+C C+ G+ G CE D++EC
Sbjct: 2568 ACIDNNECGSQPSLCGAKGI--CQNTPGSFSCECQRGFSLDATGLNCE-DVDECDG---- 2620
Query: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
N C C N G Y C C G++ C D +ECS P+ CG+A C N G ++C
Sbjct: 2621 NHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECS-NPNACGSASCYNTLGSYKCA 2679
Query: 228 CPEGYRYNLKSKSCEDIDEC--SENMCAQLCVNYPGGYTCYC 267
CP G+ ++ S +C D++EC S+N C C N GGY C C
Sbjct: 2680 CPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGC 2721
Score = 105 bits (262), Expect = 1e-22
Identities = 60/177 (33%), Positives = 82/177 (46%), Gaps = 21/177 (11%)
Query: 113 CVNAIPDQ-----CSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECK-DPSN 166
C A PD C P P A F C G DINEC DP
Sbjct: 728 CCCANPDYGFGEPCQPCPAKNS---------AEFHGLCSSGVGITVDGRDINECALDPDI 778
Query: 167 INGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFEC 226
G IC+N GSY C+C +G+ ++ ++C D+DEC + +C +C+N PG + C
Sbjct: 779 CANG---ICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSC 835
Query: 227 ECPEGYRYNLKSKSCEDIDECSENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
CP GY + ++++CEDI+EC N C C N G + C C G KL+ C
Sbjct: 836 TCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCEC--SPGSKLSSTGLIC 890
Score = 101 bits (252), Expect = 2e-21
Identities = 69/193 (35%), Positives = 91/193 (47%), Gaps = 20/193 (10%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE---KCEFDINECKDP 164
PD RSC + D+C P DG C + + C C G+ K D+NEC
Sbjct: 1276 PDGRSCADI--DECENNPDICDGGQ-CTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLN 1332
Query: 165 SNINGGCS-QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPG 222
SNI C C+NT GS+ C C+ G+ + C DVDEC + C A C NIPG
Sbjct: 1333 SNI---CMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPG 1389
Query: 223 DFECECPEGYRYNLKSKSCEDIDECSE--NMCA--QLCVNYPGGYTCYCD---GKKGFKL 275
F+C C EG+ N C D+DECS + C+ CVN PG Y C C GF
Sbjct: 1390 SFKCSCREGWIGN--GIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTC 1447
Query: 276 AQDQKSCEVVSVC 288
+ + E +++C
Sbjct: 1448 SDVDECAENINLC 1460
Score = 101 bits (252), Expect = 2e-21
Identities = 66/208 (31%), Positives = 96/208 (46%), Gaps = 20/208 (9%)
Query: 88 CLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKP 147
C +F+ G + + + C + +P + PC + KD + +F C
Sbjct: 2104 CFTNFENGKCSVPKAFNTT--KAKCCCSKMPGEGWGDPCE----LCPKDDEVAFQDLCPY 2157
Query: 148 GWQG----EKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDV 202
G D+NEC + I CS C NT GS+ C C G+ + C D
Sbjct: 2158 GHGTVPSLHDTREDVNECLESPGI---CSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT 2214
Query: 203 DECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQLCVNYP 260
DECS+ + CG C N+ G FEC C EG+ +CEDI+EC++N +CA C+N
Sbjct: 2215 DECSIG-NPCGNGTCTNVIGSFECNCNEGFEPG-PMMNCEDINECAQNPLLCAFRCMNTF 2272
Query: 261 GGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
G Y C C G+ L +DQK C+ + C
Sbjct: 2273 GSYECTCP--IGYALREDQKMCKDLDEC 2298
Score = 96.7 bits (239), Expect = 6e-20
Identities = 72/217 (33%), Positives = 103/217 (47%), Gaps = 33/217 (15%)
Query: 112 SCVNAIPDQ---CSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCE----FDINE--CK 162
+C N + + C P +G +C D + SF C + G CE F++ + C
Sbjct: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSF---CYRSYNGTTCENELPFNVTKRMCC 1763
Query: 163 DPSNINGGCSQICDN--TPGS--YHCSCKN--GFVMLSNKKDCKDVDECSLKPSICGTAV 216
N+ ++ C+ TPG+ + C N GF + D+DEC P IC V
Sbjct: 1764 CTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGV 1823
Query: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCAQL--CVNYPGGYTCYCDGKKG 272
C N G F CECP G+ YN CEDIDECS +N+C + C+N PG Y C C G
Sbjct: 1824 CINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCEC--AAG 1881
Query: 273 FKLAQ-----DQKSC-EVVSVC---LPLNLDTKYELL 300
FKL+ D+ C E+ +VC L ++L Y+ +
Sbjct: 1882 FKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCI 1918
Score = 95.1 bits (235), Expect = 2e-19
Identities = 55/137 (40%), Positives = 75/137 (54%), Gaps = 11/137 (8%)
Query: 157 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG-T 214
DI+ECK+ I G C+ +C N GS+ C C GF C+D+DECS ++C
Sbjct: 1808 DIDECKE---IPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1864
Query: 215 AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQ-LCVNYPGGYTCYCDGKK 271
A C N PG + CEC G++ + + +C D +EC E N+C+ LCV+ G Y C C
Sbjct: 1865 ADCINSPGSYRCECAAGFKLS-PNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHN-- 1921
Query: 272 GFKLAQDQKSCEVVSVC 288
GFK +QDQ C V C
Sbjct: 1922 GFKASQDQTMCMDVDEC 1938
Score = 94.4 bits (233), Expect = 3e-19
Identities = 63/179 (35%), Positives = 88/179 (49%), Gaps = 20/179 (11%)
Query: 113 CVNAIPDQCS-PLPCNEDGYMSCKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNIN 168
CV+ D+CS PC G +C + SF C C G++ CE DINEC +
Sbjct: 2211 CVDT--DECSIGNPC---GNGTCTNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLL- 2263
Query: 169 GGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGT--AVCKNIPGDFEC 226
C+ C NT GSY C+C G+ + ++K CKD+DEC+ C + +CKN+ G F C
Sbjct: 2264 --CAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMC 2321
Query: 227 ECPEGYRYNLKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
CP G + C D +EC +C CVN G Y C C+ +GF+ + C
Sbjct: 2322 ICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECN--EGFQSSSSGTEC 2378
Score = 93.6 bits (231), Expect = 5e-19
Identities = 56/175 (32%), Positives = 82/175 (46%), Gaps = 19/175 (10%)
Query: 119 DQCSPLP--CNEDGYMSCKDGKASFTCTCKPGWQGEK----CEFDINECKDPSNINGGCS 172
D+C +P C C + SF C C G+ CE DI+EC + N+ C
Sbjct: 1810 DECKEIPGICANG---VCINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNL---CQ 1862
Query: 173 QICD--NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPE 230
+ D N+PGSY C C GF LS C D +EC P++C +C ++ G ++C C
Sbjct: 1863 RNADCINSPGSYRCECAAGF-KLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHN 1921
Query: 231 GYRYNLKSKSCEDIDECSENMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEV 284
G++ + C D+DEC + C C N G Y C C GF+L + ++
Sbjct: 1922 GFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLC--YPGFELTHNNDCLDI 1974
Score = 87.8 bits (216), Expect = 3e-17
Identities = 52/141 (36%), Positives = 71/141 (50%), Gaps = 14/141 (9%)
Query: 158 INECKDPSNI--NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
I+ CK +N+ NG C T SY C C G+ +N DC DVDEC+ P C
Sbjct: 495 IDICKHHANLCLNGRCIP----TVSSYRCECNMGYKQDANG-DCIDVDECTSNP--CTNG 547
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKG 272
C N PG + C+C G++ ++C DIDEC +N +C CVN G + C C+ G
Sbjct: 548 DCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNA--G 605
Query: 273 FKLAQDQKSCEVVSVCLPLNL 293
F+L D K+C C N+
Sbjct: 606 FELTTDGKNCVDHDECTTTNM 626
Score = 84.3 bits (207), Expect = 3e-16
Identities = 54/158 (34%), Positives = 74/158 (46%), Gaps = 22/158 (13%)
Query: 126 CNEDGYMSCKDGKA-----SFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICD 176
C ++G + CK+G+ SF C C G++ G+ C D +EC + G +C
Sbjct: 579 CIQNGVL-CKNGRCVNTDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNG---MCI 633
Query: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
N GS+ C CK GFV+ N + C DVDEC P IC C N G F C+CP G +
Sbjct: 634 NEDGSFKCICKPGFVLAPNGRYCTDVDECQT-PGICMNGHCINSEGSFRCDCPPGLAVGM 692
Query: 237 KSKSCEDI---DECSENMCAQLCVN-YPGGYT---CYC 267
+ C D C + +CV +PG T C C
Sbjct: 693 DGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCC 730
Score = 82.4 bits (202), Expect = 1e-15
Identities = 63/216 (29%), Positives = 87/216 (40%), Gaps = 45/216 (20%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 167
PD CV+ + P C E+G C + S+ C C G+Q EC D N
Sbjct: 2331 PDGEGCVDENECRTKPGIC-ENG--RCVNIIGSYRCECNEGFQSSSSG---TECLD--NR 2382
Query: 168 NGGC-----SQICDNTPGSYH------CSCKNGFVM------------LSNKKDC----- 199
G C IC S + C C G KK C
Sbjct: 2383 QGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPG 2442
Query: 200 -----KDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSEN--MC 252
+D+DEC + P++C C N G F C C GY ++ SC D+DECS++ C
Sbjct: 2443 YTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC 2502
Query: 253 AQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
+C N G Y C C +G+ L +D K+C+ + C
Sbjct: 2503 NYICKNTEGSYQCSC--PRGYVLQEDGKTCKDLDEC 2536
Score = 81.3 bits (199), Expect = 3e-15
Identities = 52/165 (31%), Positives = 70/165 (42%), Gaps = 27/165 (16%)
Query: 143 CTCKPGWQGEKCEFDINECKDPSNINGGCSQ-----------ICDNTPG---SYHCS--- 185
C C G+ G +CE D + +N Q +C T G + C
Sbjct: 196 CACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
Query: 186 -----CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS 240
C+ GF+ C+DVDEC P IC C N G FEC CP G++ + ++
Sbjct: 256 AQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQK 315
Query: 241 CEDIDECS--ENMC-AQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
CEDIDECS +C C N G Y C C +G+ + D C
Sbjct: 316 CEDIDECSIIPGICETGECSNTVGSYFCVC--PRGYVTSTDGSRC 358
Score = 80.1 bits (196), Expect = 6e-15
Identities = 69/261 (26%), Positives = 95/261 (36%), Gaps = 92/261 (35%)
Query: 108 PDLRSCVN-----AIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINE 160
PD ++C++ A+P CSP +C++ + SF C C PG++ E C DINE
Sbjct: 2009 PDGKNCIDTNECVALPGSCSP--------GTCQNLEGSFRCICPPGYEVKSENC-IDINE 2059
Query: 161 CKDPSNI-------------------------------------------NGGCSQ---- 173
C + NI NG CS
Sbjct: 2060 CDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAF 2119
Query: 174 -------ICDNTPG----------------SYHCSCKNGFVMLSNKKDCK-DVDECSLKP 209
C PG ++ C G + + D + DV+EC P
Sbjct: 2120 NTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESP 2179
Query: 210 SICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS-ENMCAQ-LCVNYPGGYTCYC 267
IC C N G F CECP GY + C D DECS N C C N G + C C
Sbjct: 2180 GICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNC 2239
Query: 268 DGKKGFKLAQDQKSCEVVSVC 288
+ +GF+ +CE ++ C
Sbjct: 2240 N--EGFE-PGPMMNCEDINEC 2257
Score = 77.0 bits (188), Expect = 5e-14
Identities = 57/186 (30%), Positives = 87/186 (46%), Gaps = 24/186 (12%)
Query: 111 RSCVNAIPDQCSPLPCNEDGYMSCKDGKASF-TCTCKPG--WQGEKCEFDINECKDPSNI 167
R C++ +QC L +ED + GK C C G W G +CE EC P
Sbjct: 993 RVCLDIRMEQCY-LKWDEDECIHPVPGKFRMDACCCAVGAAW-GTECE----ECPKPGTK 1046
Query: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
+C G N +L+ + KD++EC P +C C+N G F+C
Sbjct: 1047 E--YETLCPRGAGF-----ANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCR 1099
Query: 228 CPEGYRYNLKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYC-DG-KKGFKLAQDQKSC 282
C G+ +++ ++C DIDEC S ++C +CVN PG + C C +G + GF + K+C
Sbjct: 1100 CNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMM---MKNC 1156
Query: 283 EVVSVC 288
+ C
Sbjct: 1157 MDIDEC 1162
Score = 77.0 bits (188), Expect = 5e-14
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 11/151 (7%)
Query: 134 CKDGKASFTCTCKPGW---QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
C + S+ CTC G+ + +K D++EC + + +C N G++ C C G
Sbjct: 2268 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGM 2327
Query: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED------I 244
+ + C D +EC KP IC C NI G + CEC EG++ + C D
Sbjct: 2328 ARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCF 2387
Query: 245 DECSENMC--AQLCVNYPGGYTCYCDGKKGF 273
E + +C A N C CDG +G+
Sbjct: 2388 AEVLQTICQMASSSRNLVTKSECCCDGGRGW 2418
Score = 76.3 bits (186), Expect = 9e-14
Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 16/120 (13%)
Query: 134 CKDGKA-----SFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYH 183
C++G+ SF C C G++ G+ C D NEC + G CS C N GS+
Sbjct: 1985 CRNGRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVA---LPGSCSPGTCQNLEGSFR 2040
Query: 184 CSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
C C G+ + S ++C D++EC P+IC C N PG F+C CP G+ + + C D
Sbjct: 2041 CICPPGYEVKS--ENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2098
Score = 73.2 bits (178), Expect = 8e-13
Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 8/134 (5%)
Query: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
D++EC+ I G + C NT GS+ C C G + C+D+DECS+ P IC T
Sbjct: 276 DVDECQAIPGICQGGN--CINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGE 333
Query: 217 CKNIPGDFECECPEGYRYNLKSKSCED--IDECSENMCAQLCV-NYPGGYT---CYCDGK 270
C N G + C CP GY + C D C + C PG T C C+
Sbjct: 334 CSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
Query: 271 KGFKLAQDQKSCEV 284
+ + + ++C V
Sbjct: 394 RCWGIGTIPEACPV 407
Score = 72.4 bits (176), Expect = 1e-12
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 9/114 (7%)
Query: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
C + ++ C C+ G+ C+ DI+EC + G C+N PG +HC C +G
Sbjct: 1465 CLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGT---CNNLPGMFHCICDDG 1520
Query: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
+ + +C D+DEC+ P C +C N PG +EC CP ++ N C D
Sbjct: 1521 YELDRTGGNCTDIDECA-DPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVD 1573
Score = 71.6 bits (174), Expect = 2e-12
Identities = 37/110 (33%), Positives = 51/110 (46%), Gaps = 11/110 (10%)
Query: 157 DINECKD-PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
DI+EC++ P GG C NT GS+ C C G+ + + + C+D+DEC P +CG
Sbjct: 1650 DIDECQELPGLCQGGN---CINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPG 1706
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTC 265
C N G++ C CP Y +C D M C G TC
Sbjct: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMD-------MRKSFCYRSYNGTTC 1749
Score = 68.9 bits (167), Expect = 1e-11
Identities = 47/150 (31%), Positives = 62/150 (41%), Gaps = 29/150 (19%)
Query: 129 DGYMSCKD----GKASFTCTCKPG--WQGEKCEFDINECKDPSNINGGCSQICDNTPGSY 182
DG +SC G + +C C G W N C+ +N Y
Sbjct: 1588 DGSLSCNTEIGVGVSRSSCCCSLGKAWG--------NPCETCPPVNST----------EY 1629
Query: 183 HCSCKNGFVMLSNKKDC--KDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS 240
+ C G N +D+DEC P +C C N G F+CECP+GY + ++
Sbjct: 1630 YTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRI 1689
Query: 241 CEDIDEC--SENMCAQ-LCVNYPGGYTCYC 267
CEDIDEC +C C N G YTC C
Sbjct: 1690 CEDIDECFAHPGVCGPGTCYNTLGNYTCIC 1719
Score = 67.0 bits (162), Expect = 5e-11
Identities = 38/103 (36%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 134 CKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
C++ + C C G+ Q +C D NEC +P N S C NT GSY C+C +G
Sbjct: 2628 CQNILGGYRCGCPQGYIQHYQWNQC-VDENECSNP---NACGSASCYNTLGSYKCACPSG 2683
Query: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
F C DV+ECS + C C N G + C CP GY
Sbjct: 2684 FSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2725
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/178 (25%), Positives = 71/178 (39%), Gaps = 33/178 (18%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK------------CEFDINECKDPSN 166
++C PC +C++ SF C C PG + C +I + + N
Sbjct: 854 NECESNPCVNG---ACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVN 910
Query: 167 INGGC--SQICDNTPGSY---------HCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
ING S+ C ++ +C G + C+DV+EC + P +C
Sbjct: 911 INGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVT-CEDVNECEVFPGVCPNG 969
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDI--DECSENMCAQLCVN-YPGGY---TCYC 267
C N G F CECPEG + + C DI ++C C++ PG + C C
Sbjct: 970 RCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCC 1027
Score = 43.5 bits (101), Expect = 6e-04
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 127 NEDGYMSCKDGKASFTCTCKPGWQGEKCE---FDINECKDPSNINGGCSQICDNTPGSYH 183
N G SC + S+ C C G+ ++ D+NEC N C+ C NT G Y
Sbjct: 2662 NACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKN---PCNYGCSNTEGGYL 2718
Query: 184 CSCKNGF 190
C C G+
Sbjct: 2719 CGCPPGY 2725
>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
Length = 488
Score = 125 bits (313), Expect = 2e-28
Identities = 74/190 (38%), Positives = 97/190 (51%), Gaps = 36/190 (18%)
Query: 11 LLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEARE 70
L A L +L + E+ F+ ++QA+ +L R RANS LEE K+G+LEREC+EE C+ EEARE
Sbjct: 10 LSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEARE 69
Query: 71 VFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDG 130
VFE+ +T+ F+ KY + G DQC PC G
Sbjct: 70 VFEDSDKTNEFWNKY-------KDG-----------------------DQCETSPCQNQG 99
Query: 131 YMSCKDGKASFTCTCKPGWQGEKCE-FDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
CKDG +TCTC G++G+ CE F C S NG C Q C S CSC G
Sbjct: 100 --KCKDGLGEYTCTCLEGFEGKNCELFTRKLC---SLDNGDCDQFCHEEQNSVVCSCARG 154
Query: 190 FVMLSNKKDC 199
+ + N K C
Sbjct: 155 YTLADNGKAC 164
Score = 39.7 bits (91), Expect = 0.009
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 11/87 (12%)
Query: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCE----DIDECSENMCAQL 255
KD D+C P CK+ G++ C C EG+ + K+CE + C Q
Sbjct: 85 KDGDQCETSPCQ-NQGKCKDGLGEYTCTCLEGF----EGKNCELFTRKLCSLDNGDCDQF 139
Query: 256 CVNYPGGYTCYCDGKKGFKLAQDQKSC 282
C C C +G+ LA + K+C
Sbjct: 140 CHEEQNSVVCSC--ARGYTLADNGKAC 164
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 123 bits (308), Expect = 6e-28
Identities = 61/157 (38%), Positives = 79/157 (50%), Gaps = 15/157 (9%)
Query: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCS 172
D+CS P PC G+ C + SF C C G+ G CE D+NEC P C
Sbjct: 2487 DECSAQPGPCGAHGH--CHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHR----CQ 2539
Query: 173 QICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
C N G Y CSC GF S C D +EC+L P CG+A C+N G F C CP G+
Sbjct: 2540 HGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGF 2599
Query: 233 RYNLKSKSCEDIDECS--ENMCAQLCVNYPGGYTCYC 267
++ C+++DEC+ C+ C N PGG+ C C
Sbjct: 2600 DFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCGC 2636
Score = 119 bits (298), Expect = 9e-27
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 13/180 (7%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCE-FDINECKDPSNINGGCSQI--C 175
D+C N D + SC + SF+C C PGW G+ E D++EC + CS C
Sbjct: 1282 DECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH---RCSPRGDC 1338
Query: 176 DNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYN 235
N PGSY C+C+ GF + C+D DEC+ +C C N PG + CEC G+
Sbjct: 1339 LNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPT 1396
Query: 236 LKSKSCEDIDECSE-NMCA-QLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL-PLN 292
++C+D+DEC++ N+CA C N PG + C C+G G++L + +C ++ C P+N
Sbjct: 1397 EDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNG--GYELDRGGGNCTDINECADPVN 1454
Score = 112 bits (281), Expect = 9e-25
Identities = 63/186 (33%), Positives = 90/186 (48%), Gaps = 17/186 (9%)
Query: 111 RSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQG-----EKCEFDINEC-KDP 164
R+C + + SP C G +C + SF C C PG++ + C D++EC +DP
Sbjct: 1024 RNCTDIDECRISPDLC---GQGTCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDP 1079
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDF 224
GG C NT GSY C C G + + C+D+DECSL +C C N+ G F
Sbjct: 1080 LLCRGGT---CTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAF 1136
Query: 225 ECECPEGYRYNLKSKSCEDIDEC--SENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+C C G++ + C DI+EC C C+N G Y C C +G+ L D ++C
Sbjct: 1137 QCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCG--QGYSLMPDGRAC 1194
Query: 283 EVVSVC 288
V C
Sbjct: 1195 ADVDEC 1200
Score = 111 bits (277), Expect = 2e-24
Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 10/137 (7%)
Query: 157 DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
D+NECK G C+ C NT GS+HC+C GF + + +++C D+DEC + P +CG
Sbjct: 986 DVNECKV---FPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 216 VCKNIPGDFECECPEGYRYN-LKSKSCEDIDECSEN--MC-AQLCVNYPGGYTCYCDGKK 271
C N PG FECEC GY + K+C D+DEC+ + +C C N G Y C C
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQC--PP 1100
Query: 272 GFKLAQDQKSCEVVSVC 288
G +L +CE + C
Sbjct: 1101 GHELTAKGTACEDIDEC 1117
Score = 110 bits (276), Expect = 3e-24
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 15/162 (9%)
Query: 134 CKDGKASFTCTCKPGWQG----EKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
C + +F C+C G+Q + C DINEC+ NGGC C NT GSY CSC G
Sbjct: 1129 CVNVIGAFQCSCHAGFQSTPDRQGC-VDINECRVQ---NGGCDVHCINTEGSYRCSCGQG 1184
Query: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE 249
+ ++ + + C DVDEC P +C C N+PG C C +G+ ++C D+DEC
Sbjct: 1185 YSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDL 1244
Query: 250 NMCAQL---CVNYPGGYTCYCD----GKKGFKLAQDQKSCEV 284
N L C N G + C+C +KG D CEV
Sbjct: 1245 NPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEV 1286
Score = 108 bits (271), Expect = 1e-23
Identities = 59/157 (37%), Positives = 76/157 (48%), Gaps = 9/157 (5%)
Query: 113 CVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECK-DPSNINGGC 171
C A PD PC KD A F C G DINEC DP G
Sbjct: 642 CCCANPDHGFGEPCQ---LCPAKDS-AEFQALCSSGLGITTDGRDINECALDPEVCANG- 696
Query: 172 SQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
+C+N GSY C C G+ ++ KDC DVDEC+L +C C+N PG + C CP G
Sbjct: 697 --VCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPG 754
Query: 232 YRYNLKSKSCEDIDECSENMCAQ-LCVNYPGGYTCYC 267
+ + ++ C+D+DEC + C +C N G YTC C
Sbjct: 755 FHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKC 791
Score = 108 bits (270), Expect = 2e-23
Identities = 63/173 (36%), Positives = 91/173 (52%), Gaps = 21/173 (12%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQI 174
D+C PC G +CK+ S+ C C PG+ G+ +FD EC + + G +
Sbjct: 1849 DECDRQPC---GNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFD--EC---TTLVGQVCRF 1900
Query: 175 --CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
C NT GS+HC C++GF + ++ K+C D +EC C C+N+ G F C CP G+
Sbjct: 1901 GHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF 1960
Query: 233 RYNLKSKSCEDIDECSE--NMCA-QLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+ ++S C DIDECSE N+C C N PG + C C GF L+ + C
Sbjct: 1961 Q--VQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLC--PPGFVLSDNGHRC 2009
Score = 108 bits (269), Expect = 2e-23
Identities = 68/196 (34%), Positives = 99/196 (50%), Gaps = 19/196 (9%)
Query: 106 AYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK----CEFDINEC 161
A PD+R+CV+ +P C C++ K SF C C+ G+ K C D++EC
Sbjct: 1229 ATPDMRTCVDVDECDLNPHICLHG---DCENTKGSFVCHCQLGYMVRKGATGCS-DVDEC 1284
Query: 162 KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNI 220
+ + N C N PGS+ C C G+V + +C D+DEC + C C N+
Sbjct: 1285 EVGGH-NCDSHASCLNIPGSFSCRCLPGWV--GDGFECHDLDECVSQEHRCSPRGDCLNV 1341
Query: 221 PGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLAQ 277
PG + C C +G+ + CED DEC+EN +C C+N PGGY C C+ GF +
Sbjct: 1342 PGSYRCTCRQGFAGD--GFFCEDRDECAENVDLCDNGQCLNAPGGYRCECE--MGFDPTE 1397
Query: 278 DQKSCEVVSVCLPLNL 293
D ++C+ V C NL
Sbjct: 1398 DHRACQDVDECAQGNL 1413
Score = 99.0 bits (245), Expect = 1e-20
Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 12/160 (7%)
Query: 134 CKDGKASFTCTCKPGWQGE---KCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
C +S+ C C G+ + +C D++EC +G C N PG+YHC C GF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRGEC-IDVDECTSSPCHHGDCV----NIPGTYHCRCYPGF 478
Query: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SE 249
++ C DVDEC + +C C N G F+C C G+ + K+C D +EC +
Sbjct: 479 QATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATS 538
Query: 250 NMCAQ-LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
MC +C+N G ++C C K GF LA C + C
Sbjct: 539 TMCVNGVCLNEDGSFSCLC--KPGFLLAPGGHYCMDIDEC 576
Score = 96.7 bits (239), Expect = 6e-20
Identities = 55/162 (33%), Positives = 81/162 (50%), Gaps = 15/162 (9%)
Query: 134 CKDGKASFTCTCKPGWQGEKCE---FDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
C + SF C C+ G+ + D++EC S + C+ +C NT GS+ CSC G+
Sbjct: 2379 CINSLGSFRCHCQAGYTPDATATTCLDMDEC---SQVPKPCTFLCKNTKGSFLCSCPRGY 2435
Query: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS-- 248
++ + + CKD+DEC+ + C +C N G F C CP G+ + ++C D DECS
Sbjct: 2436 LLEEDGRTCKDLDECTSRQHNC-QFLCVNTVGAFTCRCPPGFTQH--HQACFDNDECSAQ 2492
Query: 249 ENMCAQ--LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
C C N PG + C C +GF L CE V+ C
Sbjct: 2493 PGPCGAHGHCHNTPGSFRCEC--HQGFTLVSSGHGCEDVNEC 2532
Score = 95.5 bits (236), Expect = 1e-19
Identities = 62/184 (33%), Positives = 90/184 (48%), Gaps = 23/184 (12%)
Query: 119 DQCSPL--PCNEDGYMSCKDGKASFTCTCKPGWQ---GEKCEFDINECKDPSNINGGCSQ 173
D+C PC ++ C + S+ C C G++ G C NEC++ N+ CS
Sbjct: 1765 DECGSRESPCQQNA--DCINIPGSYRCKCTRGYKLSPGGAC-VGRNECREIPNV---CSH 1818
Query: 174 -ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
C +T GSY C C GF +++ C D+DEC +P CG CKNI G + C C G+
Sbjct: 1819 GDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGF 1876
Query: 233 RYNLKSKSCEDIDECSENMCAQLC-----VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSV 287
+ C D DEC+ + Q+C +N G + C C + GF+L D K+C +
Sbjct: 1877 VVT-HNGDCVDFDECT-TLVGQVCRFGHCLNTAGSFHCLC--QDGFELTADGKNCVDTNE 1932
Query: 288 CLPL 291
CL L
Sbjct: 1933 CLSL 1936
Score = 87.4 bits (215), Expect = 4e-17
Identities = 46/133 (34%), Positives = 65/133 (48%), Gaps = 9/133 (6%)
Query: 161 CKDPSNINGGCSQICD-NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKN 219
C +P + G Q+C + C +G L D +D++EC+L P +C VC+N
Sbjct: 644 CANPDHGFGEPCQLCPAKDSAEFQALCSSG---LGITTDGRDINECALDPEVCANGVCEN 700
Query: 220 IPGDFECECPEGYRYNLKSKSCEDIDECSEN--MCAQ-LCVNYPGGYTCYCDGKKGFKLA 276
+ G + C C GY K C D+DEC+ N +C C N PG Y+C C GF
Sbjct: 701 LRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCP--PGFHFW 758
Query: 277 QDQKSCEVVSVCL 289
QD + C+ V CL
Sbjct: 759 QDTEICKDVDECL 771
Score = 83.6 bits (205), Expect = 6e-16
Identities = 56/181 (30%), Positives = 81/181 (44%), Gaps = 18/181 (9%)
Query: 112 SCVNAIPDQCSPLPCNE---DGYMSCKDGKASFTCTCKPGWQGEKCEFDINE--CKDPSN 166
+C N + + P +G +C D + S G + F++ C N
Sbjct: 1620 TCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYN 1679
Query: 167 INGGCSQICDNTPG----SYHCSCKN---GFVMLSNKKDCKDVDECSLKPSICGTAVCKN 219
I ++ C+ P Y C N GF+ + D+DEC P+IC +C N
Sbjct: 1680 IGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICIN 1739
Query: 220 IPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCAQL--CVNYPGGYTCYCDGKKGFKL 275
G F CECP G+ YN +CED+DEC E+ C Q C+N PG Y C C +G+KL
Sbjct: 1740 QIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKC--TRGYKL 1797
Query: 276 A 276
+
Sbjct: 1798 S 1798
Score = 82.8 bits (203), Expect = 9e-16
Identities = 60/204 (29%), Positives = 84/204 (41%), Gaps = 38/204 (18%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGW----QGEKC----------EFDINECKDP 164
D+CS P N + +C + SF C C PG+ G +C F+ +C P
Sbjct: 1971 DECSEEP-NLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVP 2029
Query: 165 SNINGGCSQIC-DNTPG----------------SYHCSCKNGFVMLSNKKDCK-DVDECS 206
N ++ C PG ++ C G + D + DV+EC+
Sbjct: 2030 KAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECA 2089
Query: 207 LKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS-ENMCAQ-LCVNYPGGYT 264
P +C VC N G F CECP GY + +C D DECS + C Q C N GG+
Sbjct: 2090 ENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGTCTNVIGGFE 2149
Query: 265 CYCDGKKGFKLAQDQKSCEVVSVC 288
C C GF+ +CE + C
Sbjct: 2150 CAC--ADGFEPGL-MMTCEDIDEC 2170
Score = 82.4 bits (202), Expect = 1e-15
Identities = 49/147 (33%), Positives = 68/147 (46%), Gaps = 23/147 (15%)
Query: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ-ICDNTPGSYHCSCKN 188
C + SF C C G+ G C D +EC ++ C Q C N G + C+C +
Sbjct: 2100 CVNTDGSFRCECPFGYSLDFTGINC-VDTDEC----SVGHPCGQGTCTNVIGGFECACAD 2154
Query: 189 GF---VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245
GF +M++ C+D+DECSL P +C C N G + C CP GY C D+D
Sbjct: 2155 GFEPGLMMT----CEDIDECSLNPLLCAFR-CHNTEGSYLCTCPAGYTLREDGAMCRDVD 2209
Query: 246 ECSENM--C---AQLCVNYPGGYTCYC 267
EC++ C C N G + C C
Sbjct: 2210 ECADGQQDCHARGMECKNLIGTFACVC 2236
Score = 81.3 bits (199), Expect = 3e-15
Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 15/157 (9%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK----CEFDINEC---KDPSNINGGC 171
D+C +P + C + SF C C G+ CE D++EC + P N C
Sbjct: 1723 DECGEIPAICANGI-CINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADC 1780
Query: 172 SQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
N PGSY C C G+ LS C +EC P++C C + G + C C G
Sbjct: 1781 I----NIPGSYRCKCTRGY-KLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRG 1835
Query: 232 YRYNLKSKSCEDIDECSENMCAQ-LCVNYPGGYTCYC 267
++ + C DIDEC C C N G Y C C
Sbjct: 1836 FQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNCLC 1872
Score = 80.5 bits (197), Expect = 5e-15
Identities = 45/130 (34%), Positives = 65/130 (50%), Gaps = 11/130 (8%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ- 173
D+C+ L + C + SF C C+ G++ G+ C D NEC ++ G C
Sbjct: 1888 DECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECL---SLAGTCLPG 1943
Query: 174 ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYR 233
C N GS+ C C GF + S+ C D+DECS +P++C C N PG F+C CP G+
Sbjct: 1944 TCQNLEGSFRCICPPGFQVQSDH--CIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFV 2001
Query: 234 YNLKSKSCED 243
+ C D
Sbjct: 2002 LSDNGHRCFD 2011
Score = 77.8 bits (190), Expect = 3e-14
Identities = 60/186 (32%), Positives = 83/186 (44%), Gaps = 25/186 (13%)
Query: 111 RSCVNAIPDQCSPLPCNEDGYMSCKDGKASF-TCTCKPG--WQGEKCEFDINECKDPSNI 167
R CV+ + C L +ED GK C C G W G +CE C DP ++
Sbjct: 907 RLCVDVRLEPCF-LRWDEDECGVTLPGKYRMDVCCCSIGAVW-GVECE----ACPDPESL 960
Query: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
+ +C G LS + KDV+EC + P +C C+N G F C
Sbjct: 961 E--FASLCPRGLGFASRD------FLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCA 1012
Query: 228 CPEGYRYNLKSKSCEDIDEC--SENMCAQ-LCVNYPGGYTCYC--DGKKGFKLAQDQKSC 282
C G+ + + ++C DIDEC S ++C Q CVN PG + C C + GF L K+C
Sbjct: 1013 CAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFML---MKNC 1069
Query: 283 EVVSVC 288
V C
Sbjct: 1070 MDVDEC 1075
Score = 75.1 bits (183), Expect = 2e-13
Identities = 50/170 (29%), Positives = 71/170 (41%), Gaps = 20/170 (11%)
Query: 119 DQCS--PLPCNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCS 172
D+CS PL C C + + S+ CTC G+ G C D++EC D
Sbjct: 2168 DECSLNPLLCA----FRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADGQQDCHARG 2222
Query: 173 QICDNTPGSYHCSCKNGFVMLSNKKD-CKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
C N G++ C C G L + C D +EC +P +C C N G F C+C EG
Sbjct: 2223 MECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEG 2282
Query: 232 YRYNLKSKSCEDI------DECSENMCAQLCVNYPG--GYTCYCDGKKGF 273
++ + C DI E + MC L + C C G +G+
Sbjct: 2283 FQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGW 2332
Score = 73.2 bits (178), Expect = 8e-13
Identities = 39/114 (34%), Positives = 52/114 (45%), Gaps = 9/114 (7%)
Query: 134 CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNG 189
C + + SF C C G++ G+ C D NEC + G +C N GS+ C CK G
Sbjct: 505 CVNTEGSFQCVCNAGFELSPDGKNC-VDHNECATSTMCVNG---VCLNEDGSFSCLCKPG 560
Query: 190 FVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
F++ C D+DEC P IC C N G F C+C G + C D
Sbjct: 561 FLLAPGGHYCMDIDECQT-PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVD 613
Score = 71.2 bits (173), Expect = 3e-12
Identities = 59/189 (31%), Positives = 76/189 (40%), Gaps = 31/189 (16%)
Query: 109 DLRSC---VNAIPDQCSPLP------CNEDGYMS-----CKDGKAS--FTCTCKPGWQGE 152
D+ C VN I C P C +D ++ C D +A F T G G
Sbjct: 1445 DINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGI 1504
Query: 153 KCEFDINE-------CKDPSNINGGCSQICD--NTPGSYHCSCKNGFVMLSNKKDC--KD 201
C +I C G ++C NT Y C G N+ +D
Sbjct: 1505 SCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTT-EYRTLCPGGEGFQPNRITVILED 1563
Query: 202 VDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCAQ-LCVN 258
+DEC P +C C N G F+CECP GY + ++ CEDIDECS +C C N
Sbjct: 1564 IDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYN 1623
Query: 259 YPGGYTCYC 267
G YTC C
Sbjct: 1624 TLGNYTCVC 1632
Score = 70.1 bits (170), Expect = 6e-12
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE--NMCAQLCV 257
+DVDEC + +C C N G F C C GY + + +C D+DECS+ C LC
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCK 2421
Query: 258 NYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
N G + C C +G+ L +D ++C+ + C
Sbjct: 2422 NTKGSFLCSC--PRGYLLEEDGRTCKDLDEC 2450
Score = 69.3 bits (168), Expect = 1e-11
Identities = 39/127 (30%), Positives = 57/127 (44%), Gaps = 14/127 (11%)
Query: 157 DINECKD-PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
DI+EC++ P GG C NT GS+ C C G+ + + + C+D+DECS ICG
Sbjct: 1563 DIDECQELPGLCQGGD---CVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPG 1619
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKL 275
C N G++ C CP Y +C D M +C + Y C + F +
Sbjct: 1620 TCYNTLGNYTCVCPAEYLQVNGGNNCMD-------MRKSVCFRH---YNGTCQNELAFNV 1669
Query: 276 AQDQKSC 282
+ C
Sbjct: 1670 TRKMCCC 1676
Score = 65.9 bits (159), Expect = 1e-10
Identities = 55/206 (26%), Positives = 80/206 (38%), Gaps = 43/206 (20%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK------------CEFDINECKDPSN 166
D+C PC C++ S+TC C PG + + C I E + N
Sbjct: 768 DECLSSPCVSG---VCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVN 824
Query: 167 INGGC--SQICDNTPGSY-----HC----SCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
+ G S+ C ++ C +C GF ++ C DV+EC P +C
Sbjct: 825 LQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVT-CDDVNECESFPGVCPNG 883
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDI--DEC----SENMCAQLCVNYPGGY---TCY 266
C N G F CECPEG + + C D+ + C E+ C V PG Y C
Sbjct: 884 RCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECG---VTLPGKYRMDVCC 940
Query: 267 CDGKKGF----KLAQDQKSCEVVSVC 288
C + + D +S E S+C
Sbjct: 941 CSIGAVWGVECEACPDPESLEFASLC 966
Score = 64.3 bits (155), Expect = 3e-10
Identities = 45/155 (29%), Positives = 60/155 (38%), Gaps = 30/155 (19%)
Query: 143 CTCKPGWQGEKCEFDINE--CKDPSNINGGCSQI---------------------CDNTP 179
C C G+ G +CE D C G Q+ C+ P
Sbjct: 167 CACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCP 226
Query: 180 GSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSK 239
H C+ GF+ + C+DVDEC P +C C N+ G F C CP G+R + S
Sbjct: 227 AQPH-PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSA 285
Query: 240 SCED--IDECSENMCAQLCV-NYPGGYT---CYCD 268
+CED C + C + G YT C CD
Sbjct: 286 ACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCD 320
Score = 58.2 bits (139), Expect = 3e-08
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 4/89 (4%)
Query: 202 VDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQ-LCVNYP 260
+D C ++C C P + CEC GY +++ + C D+DEC+ + C CVN P
Sbjct: 409 IDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIP 467
Query: 261 GGYTCYCDGKKGFKLAQDQKSCEVVSVCL 289
G Y C C GF+ +++C V C+
Sbjct: 468 GTYHCRC--YPGFQATPTRQACVDVDECI 494
Score = 47.8 bits (112), Expect = 3e-05
Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 3/78 (3%)
Query: 113 CVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCS 172
CV+ SP C G SC++ F C C G+ ++ E + + G CS
Sbjct: 2566 CVDENECALSPPTC---GSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCS 2622
Query: 173 QICDNTPGSYHCSCKNGF 190
C NTPG + C C G+
Sbjct: 2623 YSCANTPGGFLCGCPQGY 2640
>gi|86788132 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 121 bits (303), Expect = 2e-27
Identities = 67/179 (37%), Positives = 92/179 (51%), Gaps = 18/179 (10%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQICD 176
D+C+ N C + + SF C C PG+Q GE+C DI+EC P C Q C
Sbjct: 175 DECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQC-VDIDECTIPPY----CHQRCV 229
Query: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
NTPGS++C C GF + +N C D++EC C NI G F C+C +GY +
Sbjct: 230 NTPGSFYCQCSPGFQLAANNYTCVDINECDASNQC--AQQCYNILGSFICQCNQGYELSS 287
Query: 237 KSKSCEDIDEC--SENMCAQLCVNYPGGYTCYCDGKKGFKL-----AQDQKSCEVVSVC 288
+CEDIDEC S +C CVN PG ++C C +G+++ QD CE + C
Sbjct: 288 DRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMC--PQGYQVVRSRTCQDINECETTNEC 344
Score = 110 bits (276), Expect = 3e-24
Identities = 61/155 (39%), Positives = 90/155 (58%), Gaps = 17/155 (10%)
Query: 119 DQCSPLP-CNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQI 174
D+C+ P C++ C + SF C C PG+Q + DINEC D SN C+Q
Sbjct: 216 DECTIPPYCHQ----RCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASN---QCAQQ 267
Query: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRY 234
C N GS+ C C G+ + S++ +C+D+DEC +C C N PG F C CP+GY+
Sbjct: 268 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ-CVNEPGKFSCMCPQGYQV 326
Query: 235 NLKSKSCEDIDEC-SENMCAQ--LCVNYPGGYTCY 266
++S++C+DI+EC + N C + +C NY GG+ CY
Sbjct: 327 -VRSRTCQDINECETTNECREDEMCWNYHGGFRCY 360
Score = 77.4 bits (189), Expect = 4e-14
Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
Query: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 239
S+ C G+ S C+D+DEC+ C VC N+ G F C+CP GY+ + +
Sbjct: 154 SHRIQCAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGE 210
Query: 240 SCEDIDECS-ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
C DIDEC+ C Q CVN PG + C C GF+LA + +C ++ C
Sbjct: 211 QCVDIDECTIPPYCHQRCVNTPGSFYCQC--SPGFQLAANNYTCVDINEC 258
Score = 38.5 bits (88), Expect = 0.021
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 4/43 (9%)
Query: 227 ECPEGYRYNLKSKSCEDIDECS--ENMC--AQLCVNYPGGYTC 265
+C +GY ++ + C+DIDEC + C CVN+ GGY C
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.0 bits (79), Expect = 0.23
Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 183 HCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFEC 226
+ C +G+ ++ CKD+DEC + P C G C N G + C
Sbjct: 26 YTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>gi|86788015 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 121 bits (303), Expect = 2e-27
Identities = 67/179 (37%), Positives = 92/179 (51%), Gaps = 18/179 (10%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQICD 176
D+C+ N C + + SF C C PG+Q GE+C DI+EC P C Q C
Sbjct: 175 DECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQC-VDIDECTIPPY----CHQRCV 229
Query: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
NTPGS++C C GF + +N C D++EC C NI G F C+C +GY +
Sbjct: 230 NTPGSFYCQCSPGFQLAANNYTCVDINECDASNQC--AQQCYNILGSFICQCNQGYELSS 287
Query: 237 KSKSCEDIDEC--SENMCAQLCVNYPGGYTCYCDGKKGFKL-----AQDQKSCEVVSVC 288
+CEDIDEC S +C CVN PG ++C C +G+++ QD CE + C
Sbjct: 288 DRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMC--PQGYQVVRSRTCQDINECETTNEC 344
Score = 110 bits (276), Expect = 3e-24
Identities = 61/155 (39%), Positives = 90/155 (58%), Gaps = 17/155 (10%)
Query: 119 DQCSPLP-CNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQI 174
D+C+ P C++ C + SF C C PG+Q + DINEC D SN C+Q
Sbjct: 216 DECTIPPYCHQ----RCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASN---QCAQQ 267
Query: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRY 234
C N GS+ C C G+ + S++ +C+D+DEC +C C N PG F C CP+GY+
Sbjct: 268 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ-CVNEPGKFSCMCPQGYQV 326
Query: 235 NLKSKSCEDIDEC-SENMCAQ--LCVNYPGGYTCY 266
++S++C+DI+EC + N C + +C NY GG+ CY
Sbjct: 327 -VRSRTCQDINECETTNECREDEMCWNYHGGFRCY 360
Score = 77.4 bits (189), Expect = 4e-14
Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
Query: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 239
S+ C G+ S C+D+DEC+ C VC N+ G F C+CP GY+ + +
Sbjct: 154 SHRIQCAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGE 210
Query: 240 SCEDIDECS-ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
C DIDEC+ C Q CVN PG + C C GF+LA + +C ++ C
Sbjct: 211 QCVDIDECTIPPYCHQRCVNTPGSFYCQC--SPGFQLAANNYTCVDINEC 258
Score = 38.5 bits (88), Expect = 0.021
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 4/43 (9%)
Query: 227 ECPEGYRYNLKSKSCEDIDECS--ENMC--AQLCVNYPGGYTC 265
+C +GY ++ + C+DIDEC + C CVN+ GGY C
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.0 bits (79), Expect = 0.23
Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 183 HCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFEC 226
+ C +G+ ++ CKD+DEC + P C G C N G + C
Sbjct: 26 YTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>gi|9665262 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 121 bits (303), Expect = 2e-27
Identities = 67/179 (37%), Positives = 92/179 (51%), Gaps = 18/179 (10%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ--GEKCEFDINECKDPSNINGGCSQICD 176
D+C+ N C + + SF C C PG+Q GE+C DI+EC P C Q C
Sbjct: 175 DECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQC-VDIDECTIPPY----CHQRCV 229
Query: 177 NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
NTPGS++C C GF + +N C D++EC C NI G F C+C +GY +
Sbjct: 230 NTPGSFYCQCSPGFQLAANNYTCVDINECDASNQC--AQQCYNILGSFICQCNQGYELSS 287
Query: 237 KSKSCEDIDEC--SENMCAQLCVNYPGGYTCYCDGKKGFKL-----AQDQKSCEVVSVC 288
+CEDIDEC S +C CVN PG ++C C +G+++ QD CE + C
Sbjct: 288 DRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMC--PQGYQVVRSRTCQDINECETTNEC 344
Score = 110 bits (276), Expect = 3e-24
Identities = 61/155 (39%), Positives = 90/155 (58%), Gaps = 17/155 (10%)
Query: 119 DQCSPLP-CNEDGYMSCKDGKASFTCTCKPGWQGEKCEF---DINECKDPSNINGGCSQI 174
D+C+ P C++ C + SF C C PG+Q + DINEC D SN C+Q
Sbjct: 216 DECTIPPYCHQ----RCVNTPGSFYCQCSPGFQLAANNYTCVDINEC-DASN---QCAQQ 267
Query: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRY 234
C N GS+ C C G+ + S++ +C+D+DEC +C C N PG F C CP+GY+
Sbjct: 268 CYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ-CVNEPGKFSCMCPQGYQV 326
Query: 235 NLKSKSCEDIDEC-SENMCAQ--LCVNYPGGYTCY 266
++S++C+DI+EC + N C + +C NY GG+ CY
Sbjct: 327 -VRSRTCQDINECETTNECREDEMCWNYHGGFRCY 360
Score = 77.4 bits (189), Expect = 4e-14
Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 7/110 (6%)
Query: 181 SYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSK 239
S+ C G+ S C+D+DEC+ C VC N+ G F C+CP GY+ + +
Sbjct: 154 SHRIQCAAGYEQ-SEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQ--KRGE 210
Query: 240 SCEDIDECS-ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
C DIDEC+ C Q CVN PG + C C GF+LA + +C ++ C
Sbjct: 211 QCVDIDECTIPPYCHQRCVNTPGSFYCQC--SPGFQLAANNYTCVDINEC 258
Score = 38.5 bits (88), Expect = 0.021
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 4/43 (9%)
Query: 227 ECPEGYRYNLKSKSCEDIDECS--ENMC--AQLCVNYPGGYTC 265
+C +GY ++ + C+DIDEC + C CVN+ GGY C
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
Score = 35.0 bits (79), Expect = 0.23
Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 183 HCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPGDFEC 226
+ C +G+ ++ CKD+DEC + P C G C N G + C
Sbjct: 26 YTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 120 bits (300), Expect = 5e-27
Identities = 70/192 (36%), Positives = 97/192 (50%), Gaps = 26/192 (13%)
Query: 102 QSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFD 157
Q A D+ C P CSP G+ C++ SF CTC G+ G C D
Sbjct: 737 QGGGACRDVNECAEGSP--CSP------GW--CENLPGSFRCTCAQGYAPAPDGRSC-LD 785
Query: 158 INECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVC 217
++EC+ + G IC NTPGS+ C C +G+ + ++ C+D+DEC P+ C C
Sbjct: 786 VDECEAGDVCDNG---ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF-PAACIGGDC 841
Query: 218 KNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQL----CVNYPGGYTCYCDGKKGF 273
N G + C CP+G+R + + C+DIDECS++ L C N G Y C CD +GF
Sbjct: 842 INTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCD--EGF 898
Query: 274 KLAQDQKSCEVV 285
QDQ CE V
Sbjct: 899 TPTQDQHGCEEV 910
Score = 114 bits (285), Expect = 3e-25
Identities = 70/201 (34%), Positives = 96/201 (47%), Gaps = 22/201 (10%)
Query: 105 NAYPDLRSCVNAIP-----DQCSPLPCNEDGYMSCKDGKASFTC-TCKPGWQ---GEKCE 155
N YP R + P D+C DG C++ SF C C+PG++ G C
Sbjct: 686 NCYPGYRLKASRPPVCEDIDECRDPSSCPDG--KCENKPGSFKCIACQPGYRSQGGGACR 743
Query: 156 FDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
D+NEC + S + G C+N PGS+ C+C G+ + + C DVDEC +C
Sbjct: 744 -DVNECAEGSPCSPGW---CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNG 798
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCAQLCVNYPGGYTCYC-DGKK- 271
+C N PG F+C+C GY + CEDIDEC C+N G Y C C G +
Sbjct: 799 ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRL 858
Query: 272 -GFKLAQDQKSC-EVVSVCLP 290
G + QD C + S+CLP
Sbjct: 859 VGGRKCQDIDECSQDPSLCLP 879
Score = 98.2 bits (243), Expect = 2e-20
Identities = 68/202 (33%), Positives = 95/202 (47%), Gaps = 23/202 (11%)
Query: 108 PDLRSCVNAIPDQCSP-----LPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDIN 159
P RS V P Q + L N G+ C G ++C C PG++ + D+N
Sbjct: 559 PPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVN 618
Query: 160 ECK-DPSNINGGCSQICDNTPGSYHCSCKNGFVML--SNKKDCKDVDECSLKPSICGT-A 215
EC+ +P G IC NT GSY+C C G+ + + + C D++EC+ KP +CG
Sbjct: 619 ECEAEPCGPGRG---ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGG 674
Query: 216 VCKNIPGDFECECPEGYRYNL-KSKSCEDIDECSE-NMCAQ-LCVNYPGGYTCY-CD--- 268
C N PG ++C C GYR + CEDIDEC + + C C N PG + C C
Sbjct: 675 FCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY 734
Query: 269 GKKGFKLAQDQKSCEVVSVCLP 290
+G +D C S C P
Sbjct: 735 RSQGGGACRDVNECAEGSPCSP 756
Score = 93.2 bits (230), Expect = 7e-19
Identities = 58/182 (31%), Positives = 88/182 (48%), Gaps = 18/182 (9%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK----CEFDINECKD 163
PD RSC++ D+C ++G C + SF C C G+ + CE DI+EC
Sbjct: 778 PDGRSCLDV--DECEAGDVCDNGI--CSNTPGSFQCQCLSGYHLSRDRSHCE-DIDECDF 832
Query: 164 PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPG 222
P+ GG C NT GSY C C G ++ +K C+D+DECS PS+C CKN+ G
Sbjct: 833 PAACIGGD---CINTNGSYRCLCPQGHRLVGGRK-CQDIDECSQDPSLCLPHGACKNLQG 888
Query: 223 DFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+ C C EG+ CE++++ + +N+ T +CD + Q + C
Sbjct: 889 SYVCVCDEGFTPTQDQHGCEEVEQPHHK--KECYLNFDD--TVFCDSVLATNVTQQECCC 944
Query: 283 EV 284
+
Sbjct: 945 SL 946
Score = 80.1 bits (196), Expect = 6e-15
Identities = 55/163 (33%), Positives = 70/163 (42%), Gaps = 20/163 (12%)
Query: 119 DQCSPLPC----NEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGG--CS 172
D C PC + + + C DGK +T G DI+EC + G C
Sbjct: 952 DHCEIYPCPVYSSAEFHSLCPDGKG-YTQDNNIVNYGIPAHRDIDECM----LFGSEICK 1006
Query: 173 Q-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
+ C NT Y C CK GF N +C DVDEC L S C VC+N G + C C
Sbjct: 1007 EGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPP 1065
Query: 232 YRYNLKSKSC-----EDIDECSENMCAQ--LCVNYPGGYTCYC 267
Y+ + C D+DEC + + CVN PG Y C C
Sbjct: 1066 AEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCEC 1108
Score = 69.7 bits (169), Expect = 8e-12
Identities = 42/130 (32%), Positives = 58/130 (44%), Gaps = 17/130 (13%)
Query: 126 CNEDGYMSCKDGKA-----SFTCTCKPG--WQGEKCE-FDINECKDPSNINGGCSQICDN 177
C G CK+GK + C CK G + G E D++EC D SN G +C+N
Sbjct: 997 CMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNG---VCEN 1053
Query: 178 TPGSYHCSCKNGFVMLSNKKDC-----KDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
T G Y C+C ++ C DVDEC P+ C C N+PG + CEC +
Sbjct: 1054 TRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQ-DPAACRPGRCVNLPGSYRCECRPPW 1112
Query: 233 RYNLKSKSCE 242
+ C+
Sbjct: 1113 VPGPSGRDCQ 1122
Score = 63.2 bits (152), Expect = 8e-10
Identities = 56/237 (23%), Positives = 85/237 (35%), Gaps = 58/237 (24%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSN------------ 166
D+CS P + +CK+ + S+ C C G+ + + E + P +
Sbjct: 868 DECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTV 927
Query: 167 ------------------INGGCSQICDNTP------GSYHCSCKNGFVMLSNKKDC--- 199
+ G C+ P +H C +G +
Sbjct: 928 FCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYG 987
Query: 200 ----KDVDECSLKPS-ICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCA 253
+D+DEC L S IC C N +EC C +G+ Y+ C D+DEC E+ C
Sbjct: 988 IPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCR 1047
Query: 254 Q-LCVNYPGGYTCYCDGKKGFKLAQ---------DQKSCEVVSVCLP---LNLDTKY 297
+C N GGY C C + AQ D C+ + C P +NL Y
Sbjct: 1048 NGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSY 1104
Score = 54.3 bits (129), Expect = 4e-07
Identities = 57/245 (23%), Positives = 90/245 (36%), Gaps = 73/245 (29%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKC----EFDINE 160
+L CV+ D+C +G C++ + + C C P + +C E D++E
Sbjct: 1030 NLLECVDV--DECLDESNCRNGV--CENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDE 1085
Query: 161 CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNI 220
C+DP+ G C N PGSY C C+ +V + +DC+ + E + + VC +
Sbjct: 1086 CQDPAACRPGR---CVNLPGSYRCECRPPWVPGPSGRDCQ-LPESPAERAPERRDVCWSQ 1141
Query: 221 PGD---------------FECECPEGYRYNLKSKSC------------------------ 241
G+ +C C +G + + + C
Sbjct: 1142 RGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSP 1201
Query: 242 --------------EDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSV 287
ED DEC + CV PGG C C G GF+L + C +
Sbjct: 1202 LLLGKPPRDEDSSEEDSDEC--RCVSGRCVPRPGGAVCECPG--GFQLDASRARCVDIDE 1257
Query: 288 CLPLN 292
C LN
Sbjct: 1258 CRELN 1262
Score = 53.9 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 13/89 (14%)
Query: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-----NMC-A 253
+D DEC C + C PG CECP G++ + C DIDEC E +C +
Sbjct: 1216 EDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKS 1270
Query: 254 QLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+ CVN G + C C K GF ++ +C
Sbjct: 1271 ERCVNTSGSFRCVC--KAGFARSRPHGAC 1297
Score = 49.7 bits (117), Expect = 9e-06
Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 10/99 (10%)
Query: 146 KPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDEC 205
KP + E D +EC+ S C PG C C GF + +++ C D+DEC
Sbjct: 1206 KPPRDEDSSEEDSDECRCVSGR-------CVPRPGGAVCECPGGFQLDASRARCVDIDEC 1258
Query: 206 ---SLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSC 241
+ + +C + C N G F C C G+ + +C
Sbjct: 1259 RELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1297
Score = 47.0 bits (110), Expect = 6e-05
Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 12/97 (12%)
Query: 204 ECSLKPSICGTAVCKNIP--GDFECECPEGYRYNLKSKSCEDIDECS-ENMCAQ-LCVNY 259
+C P + T V K P G+ +CP+GY+ L S C+DI+EC+ +C C+N
Sbjct: 315 KCHKCPQLQYTGVQKPGPVRGEVGADCPQGYK-RLNSTHCQDINECAMPGVCRHGDCLNN 373
Query: 260 PGGYTCYCDGKKGFKLAQDQKSC-----EVVSVCLPL 291
PG Y C C G L + C E S+C L
Sbjct: 374 PGSYRCVC--PPGHSLGPSRTQCIADKPEEKSLCFRL 408
Score = 47.0 bits (110), Expect = 6e-05
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 180 GSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSK 239
G C G+ L N C+D++EC++ P +C C N PG + C CP G+
Sbjct: 335 GEVGADCPQGYKRL-NSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 240 SCEDIDECSENMCAQL 255
C +++C +L
Sbjct: 393 QCIADKPEEKSLCFRL 408
Score = 34.7 bits (78), Expect = 0.30
Identities = 27/128 (21%), Positives = 50/128 (39%), Gaps = 10/128 (7%)
Query: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
DINEC P G C N PGSY C C G + ++ C + + + S+C
Sbjct: 355 DINECAMPGVCRHGD---CLNNPGSYRCVCPPGHSLGPSRTQC--IADKPEEKSLC---- 405
Query: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLA 276
+ + + +C+ P R + C + + C + + + C KG+ +
Sbjct: 406 FRLVSPEHQCQHPLTTRLT-RQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL 464
Query: 277 QDQKSCEV 284
++ +
Sbjct: 465 TSHQTLTI 472
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 120 bits (300), Expect = 5e-27
Identities = 70/192 (36%), Positives = 97/192 (50%), Gaps = 26/192 (13%)
Query: 102 QSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFD 157
Q A D+ C P CSP G+ C++ SF CTC G+ G C D
Sbjct: 737 QGGGACRDVNECAEGSP--CSP------GW--CENLPGSFRCTCAQGYAPAPDGRSC-LD 785
Query: 158 INECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVC 217
++EC+ + G IC NTPGS+ C C +G+ + ++ C+D+DEC P+ C C
Sbjct: 786 VDECEAGDVCDNG---ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDF-PAACIGGDC 841
Query: 218 KNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQL----CVNYPGGYTCYCDGKKGF 273
N G + C CP+G+R + + C+DIDECS++ L C N G Y C CD +GF
Sbjct: 842 INTNGSYRCLCPQGHRL-VGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCD--EGF 898
Query: 274 KLAQDQKSCEVV 285
QDQ CE V
Sbjct: 899 TPTQDQHGCEEV 910
Score = 114 bits (285), Expect = 3e-25
Identities = 70/201 (34%), Positives = 96/201 (47%), Gaps = 22/201 (10%)
Query: 105 NAYPDLRSCVNAIP-----DQCSPLPCNEDGYMSCKDGKASFTC-TCKPGWQ---GEKCE 155
N YP R + P D+C DG C++ SF C C+PG++ G C
Sbjct: 686 NCYPGYRLKASRPPVCEDIDECRDPSSCPDG--KCENKPGSFKCIACQPGYRSQGGGACR 743
Query: 156 FDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA 215
D+NEC + S + G C+N PGS+ C+C G+ + + C DVDEC +C
Sbjct: 744 -DVNECAEGSPCSPGW---CENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG-DVCDNG 798
Query: 216 VCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCAQLCVNYPGGYTCYC-DGKK- 271
+C N PG F+C+C GY + CEDIDEC C+N G Y C C G +
Sbjct: 799 ICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRL 858
Query: 272 -GFKLAQDQKSC-EVVSVCLP 290
G + QD C + S+CLP
Sbjct: 859 VGGRKCQDIDECSQDPSLCLP 879
Score = 98.2 bits (243), Expect = 2e-20
Identities = 68/202 (33%), Positives = 95/202 (47%), Gaps = 23/202 (11%)
Query: 108 PDLRSCVNAIPDQCSP-----LPCNEDGYMSCKDGKASFTCTCKPGWQG---EKCEFDIN 159
P RS V P Q + L N G+ C G ++C C PG++ + D+N
Sbjct: 559 PPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVN 618
Query: 160 ECK-DPSNINGGCSQICDNTPGSYHCSCKNGFVML--SNKKDCKDVDECSLKPSICGT-A 215
EC+ +P G IC NT GSY+C C G+ + + + C D++EC+ KP +CG
Sbjct: 619 ECEAEPCGPGRG---ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECA-KPHLCGDGG 674
Query: 216 VCKNIPGDFECECPEGYRYNL-KSKSCEDIDECSE-NMCAQ-LCVNYPGGYTCY-CD--- 268
C N PG ++C C GYR + CEDIDEC + + C C N PG + C C
Sbjct: 675 FCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGY 734
Query: 269 GKKGFKLAQDQKSCEVVSVCLP 290
+G +D C S C P
Sbjct: 735 RSQGGGACRDVNECAEGSPCSP 756
Score = 93.2 bits (230), Expect = 7e-19
Identities = 58/182 (31%), Positives = 88/182 (48%), Gaps = 18/182 (9%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEK----CEFDINECKD 163
PD RSC++ D+C ++G C + SF C C G+ + CE DI+EC
Sbjct: 778 PDGRSCLDV--DECEAGDVCDNGI--CSNTPGSFQCQCLSGYHLSRDRSHCE-DIDECDF 832
Query: 164 PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC-GTAVCKNIPG 222
P+ GG C NT GSY C C G ++ +K C+D+DECS PS+C CKN+ G
Sbjct: 833 PAACIGGD---CINTNGSYRCLCPQGHRLVGGRK-CQDIDECSQDPSLCLPHGACKNLQG 888
Query: 223 DFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+ C C EG+ CE++++ + +N+ T +CD + Q + C
Sbjct: 889 SYVCVCDEGFTPTQDQHGCEEVEQPHHK--KECYLNFDD--TVFCDSVLATNVTQQECCC 944
Query: 283 EV 284
+
Sbjct: 945 SL 946
Score = 62.4 bits (150), Expect = 1e-09
Identities = 50/207 (24%), Positives = 76/207 (36%), Gaps = 46/207 (22%)
Query: 119 DQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSN------------ 166
D+CS P + +CK+ + S+ C C G+ + + E + P +
Sbjct: 868 DECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTV 927
Query: 167 ------------------INGGCSQICDNTP------GSYHCSCKNGFVMLSNKKDC--- 199
+ G C+ P +H C +G +
Sbjct: 928 FCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYG 987
Query: 200 ----KDVDECSLKPS-ICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCA 253
+D+DEC L S IC C N +EC C +G+ Y+ C D+DEC E+ C
Sbjct: 988 IPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCR 1047
Query: 254 Q-LCVNYPGGYTCYCDGKKGFKLAQDQ 279
+C N GGY C C + AQ Q
Sbjct: 1048 NGVCENTRGGYRCACTPPAEYSPAQRQ 1074
Score = 61.6 bits (148), Expect = 2e-09
Identities = 44/135 (32%), Positives = 57/135 (42%), Gaps = 13/135 (9%)
Query: 119 DQCSPLPC----NEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGG--CS 172
D C PC + + + C DGK +T G DI+EC + G C
Sbjct: 952 DHCEIYPCPVYSSAEFHSLCPDGKG-YTQDNNIVNYGIPAHRDIDECM----LFGSEICK 1006
Query: 173 Q-ICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEG 231
+ C NT Y C CK GF N +C DVDEC L S C VC+N G + C C
Sbjct: 1007 EGKCVNTQPGYECYCKQGFYYDGNLLECVDVDEC-LDESNCRNGVCENTRGGYRCACTPP 1065
Query: 232 YRYNLKSKSCEDIDE 246
Y+ + C +E
Sbjct: 1066 AEYSPAQRQCLSPEE 1080
Score = 57.4 bits (137), Expect = 4e-08
Identities = 54/226 (23%), Positives = 76/226 (33%), Gaps = 66/226 (29%)
Query: 126 CNEDGYMSCKDGKA-----SFTCTCKPG--WQGEKCE-FDINECKDPSNINGGCSQICDN 177
C G CK+GK + C CK G + G E D++EC D SN G +C+N
Sbjct: 997 CMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNG---VCEN 1053
Query: 178 TPGSYHCSCKNGFVMLSNKKDCKDVDECSLKP-------------SICGTAVCKNIPGDF 224
T G Y C+C ++ C +E P +C +
Sbjct: 1054 TRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFD 1113
Query: 225 ECECPEGYRYNLKSKSC--------------------------------------EDIDE 246
+C C +G + + + C ED DE
Sbjct: 1114 DCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDE 1173
Query: 247 CSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLN 292
C + CV PGG C C G GF+L + C + C LN
Sbjct: 1174 C--RCVSGRCVPRPGGAVCECPG--GFQLDASRARCVDIDECRELN 1215
Score = 53.9 bits (128), Expect = 5e-07
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 13/89 (14%)
Query: 200 KDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-----NMC-A 253
+D DEC C + C PG CECP G++ + C DIDEC E +C +
Sbjct: 1169 EDSDECR-----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKS 1223
Query: 254 QLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+ CVN G + C C K GF ++ +C
Sbjct: 1224 ERCVNTSGSFRCVC--KAGFARSRPHGAC 1250
Score = 49.7 bits (117), Expect = 9e-06
Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 10/99 (10%)
Query: 146 KPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDEC 205
KP + E D +EC+ S C PG C C GF + +++ C D+DEC
Sbjct: 1159 KPPRDEDSSEEDSDECRCVSGR-------CVPRPGGAVCECPGGFQLDASRARCVDIDEC 1211
Query: 206 ---SLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSC 241
+ + +C + C N G F C C G+ + +C
Sbjct: 1212 RELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGAC 1250
Score = 47.0 bits (110), Expect = 6e-05
Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 12/97 (12%)
Query: 204 ECSLKPSICGTAVCKNIP--GDFECECPEGYRYNLKSKSCEDIDECS-ENMCAQ-LCVNY 259
+C P + T V K P G+ +CP+GY+ L S C+DI+EC+ +C C+N
Sbjct: 315 KCHKCPQLQYTGVQKPGPVRGEVGADCPQGYK-RLNSTHCQDINECAMPGVCRHGDCLNN 373
Query: 260 PGGYTCYCDGKKGFKLAQDQKSC-----EVVSVCLPL 291
PG Y C C G L + C E S+C L
Sbjct: 374 PGSYRCVC--PPGHSLGPSRTQCIADKPEEKSLCFRL 408
Score = 47.0 bits (110), Expect = 6e-05
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 180 GSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSK 239
G C G+ L N C+D++EC++ P +C C N PG + C CP G+
Sbjct: 335 GEVGADCPQGYKRL-NSTHCQDINECAM-PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRT 392
Query: 240 SCEDIDECSENMCAQL 255
C +++C +L
Sbjct: 393 QCIADKPEEKSLCFRL 408
Score = 34.7 bits (78), Expect = 0.30
Identities = 27/128 (21%), Positives = 50/128 (39%), Gaps = 10/128 (7%)
Query: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
DINEC P G C N PGSY C C G + ++ C + + + S+C
Sbjct: 355 DINECAMPGVCRHGD---CLNNPGSYRCVCPPGHSLGPSRTQC--IADKPEEKSLC---- 405
Query: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLA 276
+ + + +C+ P R + C + + C + + + C KG+ +
Sbjct: 406 FRLVSPEHQCQHPLTTRLT-RQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHIL 464
Query: 277 QDQKSCEV 284
++ +
Sbjct: 465 TSHQTLTI 472
>gi|10190748 CEGP1 protein [Homo sapiens]
Length = 999
Score = 120 bits (300), Expect = 5e-27
Identities = 69/173 (39%), Positives = 92/173 (53%), Gaps = 15/173 (8%)
Query: 133 SCKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
+CKD C+C G+ G+ C+ DI+EC+ NGGC C N GS+ C CK
Sbjct: 296 TCKDTSTGVHCSCPVGFTLQLDGKTCK-DIDECQTR---NGGCDHFCKNIVGSFDCGCKK 351
Query: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS 248
GF +L+++K C+DVDECSL + C + C N PG F C C GY C D +ECS
Sbjct: 352 GFKLLTDEKSCQDVDECSLDRT-CDHS-CINHPGTFACACNRGYTL-YGFTHCGDTNECS 408
Query: 249 ENM--CAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYEL 299
N C Q+CVN G Y C C G+KL ++K C V LP ++ + L
Sbjct: 409 INNGGCQQVCVNTVGSYECQC--HPGYKLHWNKKDCVEVKGLLPTSVSPRVSL 459
Score = 111 bits (278), Expect = 2e-24
Identities = 63/182 (34%), Positives = 99/182 (54%), Gaps = 21/182 (11%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSN 166
D+ C + D C+ D C++ S+ C+CKPG+QGE +CE DI+EC +
Sbjct: 45 DVDECAQGLDD------CHADAL--CQNTPTSYKCSCKPGYQGEGRQCE-DIDECGN--E 93
Query: 167 INGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFEC 226
+NGGC C N PG+Y C+C +GF++ + +C DVDEC C C N+ G +EC
Sbjct: 94 LNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGC-QHTCVNVMGSYEC 152
Query: 227 ECPEGYRYNLKSKSC----EDIDEC--SENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQK 280
C EG+ + +C E+ C ++ C+ +C P G + C+ + GF+LA++Q+
Sbjct: 153 CCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRG-SVACECRPGFELAKNQR 211
Query: 281 SC 282
C
Sbjct: 212 DC 213
Score = 106 bits (265), Expect = 6e-23
Identities = 48/121 (39%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
Query: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
NGGC + C +T HCSC GF + + K CKD+DEC + C CKNI G F+C
Sbjct: 290 NGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGC-DHFCKNIVGSFDCG 348
Query: 228 CPEGYRYNLKSKSCEDIDECS-ENMCAQLCVNYPGGYTCYCD---GKKGFKLAQDQKSCE 283
C +G++ KSC+D+DECS + C C+N+PG + C C+ GF D C
Sbjct: 349 CKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECS 408
Query: 284 V 284
+
Sbjct: 409 I 409
Score = 92.4 bits (228), Expect = 1e-18
Identities = 57/186 (30%), Positives = 82/186 (44%), Gaps = 36/186 (19%)
Query: 134 CKDG-KASFTCTCKPGWQGEKCEFD-INECKDPSNINGGCSQICDNTPGSYHCSCKNGFV 191
CK+ + S C C+PG++ K + D I C ++ NGGC CD+T CSC +
Sbjct: 188 CKEAPRGSVACECRPGFELAKNQRDCILTC---NHGNGGCQHSCDDTADGPECSCHPQYK 244
Query: 192 MLSNKKDCKDVDECSLKPSICGTA---------------------------VCKNIPGDF 224
M ++ + C + ++ L+ + T CK+
Sbjct: 245 MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGV 304
Query: 225 ECECPEGYRYNLKSKSCEDIDECS--ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
C CP G+ L K+C+DIDEC C C N G + C C KKGFKL D+KSC
Sbjct: 305 HCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGC--KKGFKLLTDEKSC 362
Query: 283 EVVSVC 288
+ V C
Sbjct: 363 QDVDEC 368
Score = 72.8 bits (177), Expect = 1e-12
Identities = 39/97 (40%), Positives = 51/97 (52%), Gaps = 8/97 (8%)
Query: 200 KDVDECSLKPSIC-GTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM---CAQL 255
+DVDEC+ C A+C+N P ++C C GY+ + + CEDIDEC + C
Sbjct: 44 EDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQG--EGRQCEDIDECGNELNGGCVHD 101
Query: 256 CVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLN 292
C+N PG Y C C GF LA D +C V CL N
Sbjct: 102 CLNIPGNYRCTCFD--GFMLAHDGHNCLDVDECLENN 136
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 118 bits (295), Expect = 2e-26
Identities = 66/188 (35%), Positives = 94/188 (50%), Gaps = 19/188 (10%)
Query: 112 SCVNAIPDQCSPL--PCNEDGYMSCKDGKASFTCT-----CKPGWQ----GEKCEFDINE 160
+CV+ ++C+ L PC SC + S+TC C G+ G KC D+NE
Sbjct: 807 NCVDI--NECTSLSEPCRPG--FSCINTVGSYTCQRNPLICARGYHASDDGTKC-VDVNE 861
Query: 161 CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNI 220
C+ + G Q+C N PGSY C CK GF + + C DV+EC P C+N
Sbjct: 862 CETGVH-RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENT 920
Query: 221 PGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQK 280
G + C C G+ K CED++EC C+Q C N G Y CYC ++G++LA+D
Sbjct: 921 LGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYC--RQGYQLAEDGH 978
Query: 281 SCEVVSVC 288
+C + C
Sbjct: 979 TCTDIDEC 986
Score = 117 bits (294), Expect = 3e-26
Identities = 65/192 (33%), Positives = 99/192 (51%), Gaps = 18/192 (9%)
Query: 105 NAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINE 160
+A D CV+ + C E C + S+ C CK G+Q G C D+NE
Sbjct: 848 HASDDGTKCVDVNECETGVHRCGEG--QVCHNLPGSYRCDCKAGFQRDAFGRGC-IDVNE 904
Query: 161 C-KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKN 219
C P + C C+NT GSY CSC +GF++ ++ K C+DV+EC + + C N
Sbjct: 905 CWASPGRL---CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC---SQECAN 958
Query: 220 IPGDFECECPEGYRYNLKSKSCEDIDECSEN---MCAQLCVNYPGGYTCYCDGKKGFKLA 276
I G ++C C +GY+ +C DIDEC++ +C C+N PG Y C C ++G+ +
Sbjct: 959 IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACP-EQGYTMT 1017
Query: 277 QDQKSCEVVSVC 288
+ +SC+ V C
Sbjct: 1018 ANGRSCKDVDEC 1029
Score = 105 bits (261), Expect = 2e-22
Identities = 52/142 (36%), Positives = 78/142 (54%), Gaps = 15/142 (10%)
Query: 133 SCKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
+C++ S+ C+C G+ G++CE D+NEC+ CSQ C N GSY C C+
Sbjct: 916 TCENTLGSYRCSCASGFLLAADGKRCE-DVNECEAQR-----CSQECANIYGSYQCYCRQ 969
Query: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPE-GYRYNLKSKSCEDIDEC 247
G+ + + C D+DEC+ I T C N+PG ++C CPE GY +SC+D+DEC
Sbjct: 970 GYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDEC 1029
Query: 248 S--ENMC--AQLCVNYPGGYTC 265
+ + C A+ C N G + C
Sbjct: 1030 ALGTHNCSEAETCHNIQGSFRC 1051
Score = 74.3 bits (181), Expect = 3e-13
Identities = 49/147 (33%), Positives = 69/147 (46%), Gaps = 22/147 (14%)
Query: 159 NECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV-C 217
N CKD NG C Q+C GS CSC G+ ++++ C+D++EC C C
Sbjct: 681 NTCKD----NGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHC 736
Query: 218 KNIPGDFEC----ECPEGYRYNLKSKSCEDIDECS--ENMCAQ--LCVNYPGGYTCYCDG 269
N G F C C GY LK CED+DEC+ + C LC N G + YC
Sbjct: 737 VNTLGSFHCYKALTCEPGYA--LKDGECEDVDECAMGTHTCQPGFLCQNTKGSF--YCQA 792
Query: 270 KK----GFKLAQDQKSCEVVSVCLPLN 292
++ GF L + +C ++ C L+
Sbjct: 793 RQRCMDGF-LQDPEGNCVDINECTSLS 818
Score = 59.3 bits (142), Expect = 1e-08
Identities = 45/155 (29%), Positives = 63/155 (40%), Gaps = 39/155 (25%)
Query: 171 CSQICDNTPGSYHCSCKNGFVMLSNKKDCKD---------VDECSLK------------- 208
C +C NT GSYHC+C GF + + + C+ E +LK
Sbjct: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
Query: 209 ----PSICG-----TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM--CA--QL 255
P+ C VC + G C C GY SCEDI+EC ++ C+ +
Sbjct: 676 PLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEH 735
Query: 256 CVNYPGGYTCY--CDGKKGFKLAQDQKSCEVVSVC 288
CVN G + CY + G+ L + CE V C
Sbjct: 736 CVNTLGSFHCYKALTCEPGYALKDGE--CEDVDEC 768
Score = 35.8 bits (81), Expect = 0.13
Identities = 29/131 (22%), Positives = 42/131 (32%), Gaps = 36/131 (27%)
Query: 193 LSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCE---------- 242
L N D DEC L P +C N G + C C G+ ++C
Sbjct: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
Query: 243 -----------------------DIDECSEN-MCAQLCVNYPGGYTCYCDGKKGFKLAQD 278
+ C +N C Q+C G C C G+ + D
Sbjct: 656 PQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSC--FPGYAIMAD 713
Query: 279 QKSCEVVSVCL 289
SCE ++ C+
Sbjct: 714 GVSCEDINECV 724
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 118 bits (295), Expect = 2e-26
Identities = 66/188 (35%), Positives = 94/188 (50%), Gaps = 19/188 (10%)
Query: 112 SCVNAIPDQCSPL--PCNEDGYMSCKDGKASFTCT-----CKPGWQ----GEKCEFDINE 160
+CV+ ++C+ L PC SC + S+TC C G+ G KC D+NE
Sbjct: 854 NCVDI--NECTSLSEPCRPG--FSCINTVGSYTCQRNPLICARGYHASDDGTKC-VDVNE 908
Query: 161 CKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNI 220
C+ + G Q+C N PGSY C CK GF + + C DV+EC P C+N
Sbjct: 909 CETGVH-RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENT 967
Query: 221 PGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQK 280
G + C C G+ K CED++EC C+Q C N G Y CYC ++G++LA+D
Sbjct: 968 LGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYC--RQGYQLAEDGH 1025
Query: 281 SCEVVSVC 288
+C + C
Sbjct: 1026 TCTDIDEC 1033
Score = 117 bits (294), Expect = 3e-26
Identities = 65/192 (33%), Positives = 99/192 (51%), Gaps = 18/192 (9%)
Query: 105 NAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINE 160
+A D CV+ + C E C + S+ C CK G+Q G C D+NE
Sbjct: 895 HASDDGTKCVDVNECETGVHRCGEG--QVCHNLPGSYRCDCKAGFQRDAFGRGC-IDVNE 951
Query: 161 C-KDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKN 219
C P + C C+NT GSY CSC +GF++ ++ K C+DV+EC + + C N
Sbjct: 952 CWASPGRL---CQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC---SQECAN 1005
Query: 220 IPGDFECECPEGYRYNLKSKSCEDIDECSEN---MCAQLCVNYPGGYTCYCDGKKGFKLA 276
I G ++C C +GY+ +C DIDEC++ +C C+N PG Y C C ++G+ +
Sbjct: 1006 IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACP-EQGYTMT 1064
Query: 277 QDQKSCEVVSVC 288
+ +SC+ V C
Sbjct: 1065 ANGRSCKDVDEC 1076
Score = 105 bits (261), Expect = 2e-22
Identities = 52/142 (36%), Positives = 78/142 (54%), Gaps = 15/142 (10%)
Query: 133 SCKDGKASFTCTCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKN 188
+C++ S+ C+C G+ G++CE D+NEC+ CSQ C N GSY C C+
Sbjct: 963 TCENTLGSYRCSCASGFLLAADGKRCE-DVNECEAQR-----CSQECANIYGSYQCYCRQ 1016
Query: 189 GFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPE-GYRYNLKSKSCEDIDEC 247
G+ + + C D+DEC+ I T C N+PG ++C CPE GY +SC+D+DEC
Sbjct: 1017 GYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDEC 1076
Query: 248 S--ENMC--AQLCVNYPGGYTC 265
+ + C A+ C N G + C
Sbjct: 1077 ALGTHNCSEAETCHNIQGSFRC 1098
Score = 73.6 bits (179), Expect = 6e-13
Identities = 66/217 (30%), Positives = 98/217 (45%), Gaps = 42/217 (19%)
Query: 108 PDLRSCVNAIPDQCSPLP------CNEDGYMS--CKDGKASFTCTCKPGW----QGEKCE 155
P L+S + + PLP C ++G C S C+C PG+ G CE
Sbjct: 659 PALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCE 718
Query: 156 FDINECKDPSNINGGCS--QICDNTPGSYHCS-----CKNGFVMLSNKKDCKDVDECSLK 208
D +EC ++ CS Q C NT GS++C C +G+++ +++K C D++EC
Sbjct: 719 -DQDECLMGAH---DCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINECVTD 773
Query: 209 PSICGTAV-CKNIPGDFEC----ECPEGYRYNLKSKSCEDIDECS--ENMCAQ--LCVNY 259
C C N G F C C GY LK CED+DEC+ + C LC N
Sbjct: 774 LHTCSRGEHCVNTLGSFHCYKALTCEPGYA--LKDGECEDVDECAMGTHTCQPGFLCQNT 831
Query: 260 PGGYTCYCDGKK----GFKLAQDQKSCEVVSVCLPLN 292
G + YC ++ GF L + +C ++ C L+
Sbjct: 832 KGSF--YCQARQRCMDGF-LQDPEGNCVDINECTSLS 865
Score = 55.8 bits (133), Expect = 1e-07
Identities = 39/130 (30%), Positives = 51/130 (39%), Gaps = 35/130 (26%)
Query: 171 CSQICDNTPGSYHCSCKNGFVMLSNKKDCKD---------VDECSLK------------- 208
C +C NT GSYHC+C GF + + + C+ E +LK
Sbjct: 616 CQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPL 675
Query: 209 ----PSICG-----TAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC--SENMCA--QL 255
P+ C VC + G C C GY SCED DEC + C+ Q
Sbjct: 676 PLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQF 735
Query: 256 CVNYPGGYTC 265
CVN G + C
Sbjct: 736 CVNTLGSFYC 745
Score = 34.7 bits (78), Expect = 0.30
Identities = 30/131 (22%), Positives = 40/131 (30%), Gaps = 36/131 (27%)
Query: 193 LSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCE---------- 242
L N D DEC L P +C N G + C C G+ ++C
Sbjct: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
Query: 243 -----------------------DIDECSEN-MCAQLCVNYPGGYTCYCDGKKGFKLAQD 278
+ C +N C Q+C G C C G+ + D
Sbjct: 656 PQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSC--FPGYAIMAD 713
Query: 279 QKSCEVVSVCL 289
SCE CL
Sbjct: 714 GVSCEDQDECL 724
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 116 bits (291), Expect = 6e-26
Identities = 63/172 (36%), Positives = 86/172 (50%), Gaps = 19/172 (11%)
Query: 120 QCSPLPCNEDGYMSCKDGKASFTCTCKPG-WQGEKCEFDINECKDPSNINGGCSQICDNT 178
QC+P C + + +TC+C G W E DI+EC+ G C Q+C N
Sbjct: 137 QCNPTQI-------CINTEGGYTCSCTDGYWLLEGQCLDIDECR-----YGYCQQLCANV 184
Query: 179 PGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKS 238
PGSY C+C GF + + + C+DV+EC+ + T C N G F C C GY
Sbjct: 185 PGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQT--CVNTYGSFICRCDPGYELEEDG 242
Query: 239 KSCEDIDEC--SENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
C D+DEC SE +C CVN PG Y C C G+ L D +SC+ ++ C
Sbjct: 243 VHCSDMDECSFSEFLCQHECVNQPGTYFCSC--PPGYILLDDNRSCQDINEC 292
Score = 85.1 bits (209), Expect = 2e-16
Identities = 44/108 (40%), Positives = 56/108 (51%), Gaps = 6/108 (5%)
Query: 186 CKNGFVMLSNKKDCKDVDECSLKPSICG-TAVCKNIPGDFECECPEGYRYNLKSKSCEDI 244
C+ G+ M C DVDEC+ C T +C N G + C C +GY L C DI
Sbjct: 113 CRFGYQM-DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYW--LLEGQCLDI 169
Query: 245 DECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLN 292
DEC C QLC N PG Y+C C+ GF L +D +SC+ V+ C N
Sbjct: 170 DECRYGYCQQLCANVPGSYSCTCN--PGFTLNEDGRSCQDVNECATEN 215
Score = 73.2 bits (178), Expect = 8e-13
Identities = 42/133 (31%), Positives = 66/133 (49%), Gaps = 18/133 (13%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDP 164
D RSC + + + + PC + +C + SF C C PG++ G C D++EC
Sbjct: 201 DGRSCQD-VNECATENPCVQ----TCVNTYGSFICRCDPGYELEEDGVHCS-DMDECSFS 254
Query: 165 SNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICG-TAVCKNIPGD 223
+ C C N PG+Y CSC G+++L + + C+D++EC + C C N+ G
Sbjct: 255 EFL---CQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQQTCYNLQGG 311
Query: 224 FEC----ECPEGY 232
F+C C E Y
Sbjct: 312 FKCIDPIRCEEPY 324
Score = 43.1 bits (100), Expect = 8e-04
Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
Query: 215 AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS--ENMCA--QLCVNYPGGYTC 265
A+C PG+ + +C G+ + +S C DIDEC C +CVN GGY C
Sbjct: 14 ALCLPSPGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC 68
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 115 bits (289), Expect = 1e-25
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 22/188 (11%)
Query: 113 CVNAIPDQCSPL--PCNEDGYMSCKDGKASFTCTCKPGWQGEKCE---FDINECKD-PSN 166
CV+ D+C+P PC + C + SF C CK G+ + D+NEC+ P
Sbjct: 354 CVDV--DECAPPAEPCGKGH--RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 167 INGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFEC 226
+ C C+NT GSY CSC GF + + + C+D++ECS P + C N+ G ++C
Sbjct: 410 L---CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC---SQECANVYGSYQC 463
Query: 227 ECPEGYRYN-LKSKSCEDIDECS----ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKS 281
C GY+ + + +CEDIDEC+ ++C+ C+N PG + C C G++LA + ++
Sbjct: 464 YCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCP-SSGYRLAPNGRN 522
Query: 282 CEVVSVCL 289
C+ + C+
Sbjct: 523 CQDIDECV 530
Score = 113 bits (282), Expect = 7e-25
Identities = 60/167 (35%), Positives = 93/167 (55%), Gaps = 16/167 (9%)
Query: 133 SCKDGKASFTC-----TCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYH 183
+C + + S+TC C G+ +G +C D++EC P+ G + C N+PGS+
Sbjct: 324 TCINTEGSYTCQKNVPNCGRGYHLNEEGTRC-VDVDECAPPAEPCGKGHR-CVNSPGSFR 381
Query: 184 CSCKNGFVMLSNKKDCKDVDECSLKPS-ICGTAVCKNIPGDFECECPEGYRYNLKSKSCE 242
C CK G+ + C DV+EC P +CG C+N G + C C G+R ++ +SCE
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCE 440
Query: 243 DIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQ-DQKSCEVVSVC 288
DI+ECS + C+Q C N G Y CYC ++G++L+ D +CE + C
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYC--RRGYQLSDVDGVTCEDIDEC 485
Score = 85.9 bits (211), Expect = 1e-16
Identities = 54/137 (39%), Positives = 74/137 (54%), Gaps = 22/137 (16%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-----GEKCEFDINECKD 163
D RSC + ++CS PC+++ C + S+ C C+ G+Q G CE DI+EC
Sbjct: 435 DGRSCEDI--NECSSSPCSQE----CANVYGSYQCYCRRGYQLSDVDGVTCE-DIDECAL 487
Query: 164 PSNINGG--CSQICDNTPGSYHCSC-KNGFVMLSNKKDCKDVDECSLKPSICG-TAVCKN 219
P+ GG CS C N PGS+ CSC +G+ + N ++C+D+DEC C C N
Sbjct: 488 PT---GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFN 544
Query: 220 IPGDFEC---ECPEGYR 233
I G F C ECPE YR
Sbjct: 545 IQGGFRCLAFECPENYR 561
Score = 61.6 bits (148), Expect = 2e-09
Identities = 43/135 (31%), Positives = 61/135 (45%), Gaps = 13/135 (9%)
Query: 169 GGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA-VCKNIPGDFECE 227
G C Q C +T CSC G+ +LS+ C+DV+EC C C N G F C+
Sbjct: 184 GPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 228 ----CPEGYRYNLKSKSCEDIDECSENM--CAQ--LCVNYPGGYTC--YCDGKKGFKLAQ 277
C GY + SC+DIDEC + C +C N G + C K GF +
Sbjct: 244 RDSSCGTGYELT-EDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQD 301
Query: 278 DQKSCEVVSVCLPLN 292
+C ++ CL ++
Sbjct: 302 ALGNCIDINECLSIS 316
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 115 bits (289), Expect = 1e-25
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 22/188 (11%)
Query: 113 CVNAIPDQCSPL--PCNEDGYMSCKDGKASFTCTCKPGWQGEKCE---FDINECKD-PSN 166
CV+ D+C+P PC + C + SF C CK G+ + D+NEC+ P
Sbjct: 354 CVDV--DECAPPAEPCGKGH--RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 167 INGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFEC 226
+ C C+NT GSY CSC GF + + + C+D++ECS P + C N+ G ++C
Sbjct: 410 L---CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC---SQECANVYGSYQC 463
Query: 227 ECPEGYRYN-LKSKSCEDIDECS----ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKS 281
C GY+ + + +CEDIDEC+ ++C+ C+N PG + C C G++LA + ++
Sbjct: 464 YCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCP-SSGYRLAPNGRN 522
Query: 282 CEVVSVCL 289
C+ + C+
Sbjct: 523 CQDIDECV 530
Score = 113 bits (282), Expect = 7e-25
Identities = 60/167 (35%), Positives = 93/167 (55%), Gaps = 16/167 (9%)
Query: 133 SCKDGKASFTC-----TCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYH 183
+C + + S+TC C G+ +G +C D++EC P+ G + C N+PGS+
Sbjct: 324 TCINTEGSYTCQKNVPNCGRGYHLNEEGTRC-VDVDECAPPAEPCGKGHR-CVNSPGSFR 381
Query: 184 CSCKNGFVMLSNKKDCKDVDECSLKPS-ICGTAVCKNIPGDFECECPEGYRYNLKSKSCE 242
C CK G+ + C DV+EC P +CG C+N G + C C G+R ++ +SCE
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCE 440
Query: 243 DIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQ-DQKSCEVVSVC 288
DI+ECS + C+Q C N G Y CYC ++G++L+ D +CE + C
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYC--RRGYQLSDVDGVTCEDIDEC 485
Score = 85.9 bits (211), Expect = 1e-16
Identities = 54/137 (39%), Positives = 74/137 (54%), Gaps = 22/137 (16%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-----GEKCEFDINECKD 163
D RSC + ++CS PC+++ C + S+ C C+ G+Q G CE DI+EC
Sbjct: 435 DGRSCEDI--NECSSSPCSQE----CANVYGSYQCYCRRGYQLSDVDGVTCE-DIDECAL 487
Query: 164 PSNINGG--CSQICDNTPGSYHCSC-KNGFVMLSNKKDCKDVDECSLKPSICG-TAVCKN 219
P+ GG CS C N PGS+ CSC +G+ + N ++C+D+DEC C C N
Sbjct: 488 PT---GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFN 544
Query: 220 IPGDFEC---ECPEGYR 233
I G F C ECPE YR
Sbjct: 545 IQGGFRCLAFECPENYR 561
Score = 61.6 bits (148), Expect = 2e-09
Identities = 43/135 (31%), Positives = 61/135 (45%), Gaps = 13/135 (9%)
Query: 169 GGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA-VCKNIPGDFECE 227
G C Q C +T CSC G+ +LS+ C+DV+EC C C N G F C+
Sbjct: 184 GPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 228 ----CPEGYRYNLKSKSCEDIDECSENM--CAQ--LCVNYPGGYTC--YCDGKKGFKLAQ 277
C GY + SC+DIDEC + C +C N G + C K GF +
Sbjct: 244 RDSSCGTGYELT-EDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQD 301
Query: 278 DQKSCEVVSVCLPLN 292
+C ++ CL ++
Sbjct: 302 ALGNCIDINECLSIS 316
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 115 bits (289), Expect = 1e-25
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 22/188 (11%)
Query: 113 CVNAIPDQCSPL--PCNEDGYMSCKDGKASFTCTCKPGWQGEKCE---FDINECKD-PSN 166
CV+ D+C+P PC + C + SF C CK G+ + D+NEC+ P
Sbjct: 354 CVDV--DECAPPAEPCGKGH--RCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR 409
Query: 167 INGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFEC 226
+ C C+NT GSY CSC GF + + + C+D++ECS P + C N+ G ++C
Sbjct: 410 L---CGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPC---SQECANVYGSYQC 463
Query: 227 ECPEGYRYN-LKSKSCEDIDECS----ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKS 281
C GY+ + + +CEDIDEC+ ++C+ C+N PG + C C G++LA + ++
Sbjct: 464 YCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCP-SSGYRLAPNGRN 522
Query: 282 CEVVSVCL 289
C+ + C+
Sbjct: 523 CQDIDECV 530
Score = 113 bits (282), Expect = 7e-25
Identities = 60/167 (35%), Positives = 93/167 (55%), Gaps = 16/167 (9%)
Query: 133 SCKDGKASFTC-----TCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYH 183
+C + + S+TC C G+ +G +C D++EC P+ G + C N+PGS+
Sbjct: 324 TCINTEGSYTCQKNVPNCGRGYHLNEEGTRC-VDVDECAPPAEPCGKGHR-CVNSPGSFR 381
Query: 184 CSCKNGFVMLSNKKDCKDVDECSLKPS-ICGTAVCKNIPGDFECECPEGYRYNLKSKSCE 242
C CK G+ + C DV+EC P +CG C+N G + C C G+R ++ +SCE
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCE 440
Query: 243 DIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQ-DQKSCEVVSVC 288
DI+ECS + C+Q C N G Y CYC ++G++L+ D +CE + C
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYC--RRGYQLSDVDGVTCEDIDEC 485
Score = 89.7 bits (221), Expect = 8e-18
Identities = 61/160 (38%), Positives = 87/160 (54%), Gaps = 25/160 (15%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-----GEKCEFDINECKD 163
D RSC + ++CS PC+++ C + S+ C C+ G+Q G CE DI+EC
Sbjct: 435 DGRSCEDI--NECSSSPCSQE----CANVYGSYQCYCRRGYQLSDVDGVTCE-DIDECAL 487
Query: 164 PSNINGG--CSQICDNTPGSYHCSC-KNGFVMLSNKKDCKDVDECSLKPSICG-TAVCKN 219
P+ GG CS C N PGS+ CSC +G+ + N ++C+D+DEC C C N
Sbjct: 488 PT---GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFN 544
Query: 220 IPGDFEC---ECPEGYRYNLKSKSCEDIDECSENM-CAQL 255
I G F C ECPE YR + ++ CE + C EN C++L
Sbjct: 545 IQGGFRCLAFECPENYRRSAATR-CERL-PCHENRECSKL 582
Score = 61.6 bits (148), Expect = 2e-09
Identities = 43/135 (31%), Positives = 61/135 (45%), Gaps = 13/135 (9%)
Query: 169 GGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA-VCKNIPGDFECE 227
G C Q C +T CSC G+ +LS+ C+DV+EC C C N G F C+
Sbjct: 184 GPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 228 ----CPEGYRYNLKSKSCEDIDECSENM--CAQ--LCVNYPGGYTC--YCDGKKGFKLAQ 277
C GY + SC+DIDEC + C +C N G + C K GF +
Sbjct: 244 RDSSCGTGYELT-EDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQD 301
Query: 278 DQKSCEVVSVCLPLN 292
+C ++ CL ++
Sbjct: 302 ALGNCIDINECLSIS 316
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 115 bits (288), Expect = 1e-25
Identities = 63/155 (40%), Positives = 83/155 (53%), Gaps = 14/155 (9%)
Query: 134 CKDGKASFTCTCKPGWQ---GEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
C D CTC G+ K DI+EC+ NGGC IC NT GS+ CSCK G+
Sbjct: 251 CHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLN---NGGCDHICRNTVGSFECSCKKGY 307
Query: 191 VMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGY-RYNLKSKSCEDIDECSE 249
+L N+++C+D+DECS + +C N PG F+C C GY Y + C D+DECS
Sbjct: 308 KLLINERNCQDIDECSFDRTC--DHICVNTPGSFQCLCHRGYLLYGI--THCGDVDECSI 363
Query: 250 NM--CAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
N C C+N PG Y C C +G +L + K C
Sbjct: 364 NRGGCRFGCINTPGSYQCTCPAGQG-RLHWNGKDC 397
Score = 111 bits (278), Expect = 2e-24
Identities = 53/149 (35%), Positives = 76/149 (51%), Gaps = 11/149 (7%)
Query: 129 DGYMSCKDGKASFTCTCKPGWQGEKC--------EFDINECKDPSNIN-GGCSQICDNTP 179
D ++C G TC QG +C D C + +N GGC C +
Sbjct: 196 DCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAA 255
Query: 180 GSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSK 239
HC+C GF++ ++K CKD+DEC L C +C+N G FEC C +GY+ + +
Sbjct: 256 TGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGC-DHICRNTVGSFECSCKKGYKLLINER 314
Query: 240 SCEDIDECS-ENMCAQLCVNYPGGYTCYC 267
+C+DIDECS + C +CVN PG + C C
Sbjct: 315 NCQDIDECSFDRTCDHICVNTPGSFQCLC 343
Score = 105 bits (261), Expect = 2e-22
Identities = 53/135 (39%), Positives = 76/135 (56%), Gaps = 7/135 (5%)
Query: 150 QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKP 209
Q K D++EC + ++ N IC NTP SY C CK+G+ + K CKDVDEC +
Sbjct: 22 QYSKAAQDVDECVEGTD-NCHIDAICQNTPRSYKCICKSGYT--GDGKHCKDVDECERED 78
Query: 210 SICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM--CAQLCVNYPGGYTCYC 267
+ C NIPG++ C C +G+ +C D+DEC+E C Q CVN G Y C+C
Sbjct: 79 NAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHC 138
Query: 268 DGKKGFKLAQDQKSC 282
++GF L+ +Q +C
Sbjct: 139 --REGFFLSDNQHTC 151
Score = 100 bits (249), Expect = 4e-21
Identities = 62/194 (31%), Positives = 96/194 (49%), Gaps = 23/194 (11%)
Query: 100 ARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGW--QGEKCEFD 157
A Q + A D+ CV + C+ D C++ S+ C CK G+ G+ C+ D
Sbjct: 20 AAQYSKAAQDVDECVEGTDN------CHIDAI--CQNTPRSYKCICKSGYTGDGKHCK-D 70
Query: 158 INECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVC 217
++EC+ N GC C N PG+Y C+C +GF + + +C DVDEC+ C + C
Sbjct: 71 VDECERED--NAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQS-C 127
Query: 218 KNIPGDFECECPEGYRYNLKSKSCEDIDECSENM------CAQLCVNYP-GGYTCYCDGK 270
N+ G +EC C EG+ + +C E N CA +C P GG C C +
Sbjct: 128 VNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACEC--R 185
Query: 271 KGFKLAQDQKSCEV 284
GF+L ++Q+ C++
Sbjct: 186 PGFELTKNQRDCKL 199
Score = 94.0 bits (232), Expect = 4e-19
Identities = 51/154 (33%), Positives = 77/154 (50%), Gaps = 11/154 (7%)
Query: 138 KASFTCTCKPGWQGEKCEFDINECKDPSNI-NGGCSQICDNTPGSYHCSCKNGFVMLSNK 196
K C C+PG++ K + D CK N NGGC CD+T C C FV+ ++
Sbjct: 177 KGGIACECRPGFELTKNQRD---CKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDG 233
Query: 197 KDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENM--CAQ 254
K C ++ C++ C + C + C CP G+ K+C+DIDEC N C
Sbjct: 234 KTC--IETCAVNNGGCDSK-CHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 290
Query: 255 LCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVC 288
+C N G + C C KKG+KL ++++C+ + C
Sbjct: 291 ICRNTVGSFECSC--KKGYKLLINERNCQDIDEC 322
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 115 bits (288), Expect = 1e-25
Identities = 71/203 (34%), Positives = 99/203 (48%), Gaps = 23/203 (11%)
Query: 94 TGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGY-MSCKDGKASFTCTCKPGW--- 149
TG Q + D R+C+ + C+ N G +CKD C+C G+
Sbjct: 222 TGPTCGCHQKYALHSDGRTCI----ETCA---VNNGGCDRTCKDTATGVRCSCPVGFTLQ 274
Query: 150 -QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLK 208
G+ C+ DINEC NGGC C NT GS+ C C+ G+ +L++++ C+D+DECS +
Sbjct: 275 PDGKTCK-DINECLVN---NGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFE 330
Query: 209 PSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC--SENMCAQLCVNYPGGYTCY 266
+ +C N PG F+C C GY + C D+DEC S C Q CVN G Y C
Sbjct: 331 RTC--DHICINSPGSFQCLCHRGY-ILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECV 387
Query: 267 CDGKKGFKLAQDQKSCEVVSVCL 289
C G +L + K C CL
Sbjct: 388 C--PPGRRLHWNGKDCVETGKCL 408
Score = 112 bits (279), Expect = 1e-24
Identities = 66/176 (37%), Positives = 94/176 (53%), Gaps = 20/176 (11%)
Query: 119 DQCSPLP--CNEDGYMSCKDGKASFTCTCKPGWQGE--KCEFDINECKDPSNINGGCSQI 174
D+CS C+ D C++ S+ C CKPG++GE +CE DI+EC++ NGGC
Sbjct: 35 DECSEGTDDCHIDAI--CQNTPKSYKCLCKPGYKGEGKQCE-DIDECEN-DYYNGGCVHE 90
Query: 175 CDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRY 234
C N PG+Y C+C +GF++ + +C DVDEC C +C N G +EC+C G+
Sbjct: 91 CINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC-QQICVNAMGSYECQCHSGFFL 149
Query: 235 NLKSKSCEDIDECSENM--------CAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
+ +C I +E M CA +C P G CD + GF LAQ+QK C
Sbjct: 150 SDNQHTC--IHRSNEGMNCMNKDHGCAHICRETPKGGVA-CDCRPGFDLAQNQKDC 202
Score = 86.3 bits (212), Expect = 9e-17
Identities = 50/171 (29%), Positives = 70/171 (40%), Gaps = 45/171 (26%)
Query: 138 KASFTCTCKPGWQGEKCEFDINECKDPSNI-NGGCSQICD-------------------- 176
K C C+PG+ + + D C N NGGC C+
Sbjct: 182 KGGVACDCRPGFDLAQNQKD---CTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDG 238
Query: 177 -------------------NTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVC 217
+T CSC GF + + K CKD++EC + C C
Sbjct: 239 RTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGC-DHFC 297
Query: 218 KNIPGDFECECPEGYRYNLKSKSCEDIDECS-ENMCAQLCVNYPGGYTCYC 267
+N G FEC C +GY+ ++C+DIDECS E C +C+N PG + C C
Sbjct: 298 RNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLC 348
Score = 76.6 bits (187), Expect = 7e-14
Identities = 63/225 (28%), Positives = 84/225 (37%), Gaps = 57/225 (25%)
Query: 120 QCSPLP-CNEDGYMS-----CKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNING 169
QC + C D Y C + ++ CTC G+ G C D++EC+D NG
Sbjct: 71 QCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC-LDVDECQDN---NG 126
Query: 170 GCSQICDNTPGSYHCSCKNGFVMLSNKKDC----KDVDECSLKPSICGTAVCKNIP-GDF 224
GC QIC N GSY C C +GF + N+ C + C K C +C+ P G
Sbjct: 127 GCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH-ICRETPKGGV 185
Query: 225 ECECPEGYRYNLKSK---------------SCEDIDECSENMCAQLCVNYPGGYTCY--- 266
C+C G+ K SCED D C Q + G TC
Sbjct: 186 ACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETC 245
Query: 267 -------------------CDGKKGFKLAQDQKSCEVVSVCLPLN 292
C GF L D K+C+ ++ CL N
Sbjct: 246 AVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNN 290
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 114 bits (286), Expect = 2e-25
Identities = 70/229 (30%), Positives = 103/229 (44%), Gaps = 59/229 (25%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNI 167
PD C++A +CS C G C G A C C PG+QG +C++D++EC+
Sbjct: 118 PDEEGCLSA---ECSASLCFHGG--RCVPGSAQ-PCHCPPGFQGPRCQYDVDECRTH--- 168
Query: 168 NGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSIC--------------- 212
NGGC C NTPGSY C CK GF + ++ + C ++ C+L C
Sbjct: 169 NGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQ 228
Query: 213 ------------------------GTAV--CKNIPGDFECECPEGYRYNLKSKSCEDIDE 246
G+ + C+ + G CEC GY+ K+CED+DE
Sbjct: 229 CRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDE 288
Query: 247 CSENM--CAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC-----EVVSVC 288
C+ + CA C+N G + C C G++L D + C E+V+ C
Sbjct: 289 CAAGLAQCAHGCLNTQGSFKCVCHA--GYELGADGRQCYRIEMEIVNSC 335
Score = 108 bits (271), Expect = 1e-23
Identities = 57/159 (35%), Positives = 84/159 (52%), Gaps = 17/159 (10%)
Query: 134 CKDGKASFTCTCKPGWQ----GEKC---EFDI-NECKDPSNINGGCSQICDNTPGSYHCS 185
C + + SF C C G++ G +C E +I N C+ NGGCS C +T C+
Sbjct: 300 CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAN---NGGCSHGCSHTSAGPLCT 356
Query: 186 CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245
C G+ + ++++ C DVD+C+ P C VC N PG +EC C GYR + CED+D
Sbjct: 357 CPRGYELDTDQRTCIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVD 414
Query: 246 EC--SENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSC 282
EC S C C N G + C C+ G++L +D++ C
Sbjct: 415 ECASSRGGCEHHCTNLAGSFQCSCEA--GYRLHEDRRGC 451
Score = 94.0 bits (232), Expect = 4e-19
Identities = 77/281 (27%), Positives = 119/281 (42%), Gaps = 35/281 (12%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMS--CKDGKASFTCTCKPGWQ----GEKCEFDINECK 162
D R CV P C+ N +G C+ + C C G+Q G+ CE D++EC
Sbjct: 238 DGRHCVRRSP--CA----NRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDECA 290
Query: 163 DPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDC-----KDVDECSLKPSICGTAVC 217
C+ C NT GS+ C C G+ + ++ + C + V+ C C C
Sbjct: 291 AGL---AQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-C 346
Query: 218 KNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQ-LCVNYPGGYTCYCDGKKGFKLA 276
+ C CP GY + ++C D+D+C+++ C Q +C N PGGY C C G++L+
Sbjct: 347 SHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYA--GYRLS 404
Query: 277 QDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEG 336
D CE V C ++ LA F +RL E R + + D +G
Sbjct: 405 ADGCGCEDVDECASSRGGCEHHCTNLAGSFQ-CSCEAGYRLHEDRRGCSPLEEPMVDLDG 463
Query: 337 VILYAESIDHSAWLLIAL---------RGGKIEVQLKNEHT 368
+ + + H A L L + E +L+ EHT
Sbjct: 464 ELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHT 504
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/125 (26%), Positives = 48/125 (38%), Gaps = 18/125 (14%)
Query: 126 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDIN------ECKDPSNINGGCSQICDNTP 179
C DG+ G C+C PGW G C+ + +C P N + G CD
Sbjct: 832 CANDGHCHPATGH----CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGS-CDAIS 886
Query: 180 GSYHCSCKNGFVMLSNKKDCKD---VDECSLKPSICGTAVCKNIPGDFECECPEGYRYNL 236
G C C+ G+V ++ C C + A C ++ G C CP G+R
Sbjct: 887 GL--CLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSG--ACTCPAGWRGTF 942
Query: 237 KSKSC 241
+C
Sbjct: 943 CEHAC 947
Score = 43.5 bits (101), Expect = 6e-04
Identities = 44/158 (27%), Positives = 62/158 (39%), Gaps = 34/158 (21%)
Query: 126 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQ--------ICDN 177
C + SC K +C+CK G++GE+C+ EC + GC Q CD+
Sbjct: 656 CVQPHTQSCD--KRDGSCSCKAGFRGERCQ---AEC-ELGYFGPGCWQACTCPVGVACDS 709
Query: 178 TPGSYHCSCKNGFVMLSNKKDCKDVD---ECSLKPSICGTAVCKNIPG-----------D 223
G C GF ++C CS S CG A C + G D
Sbjct: 710 VSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS-CGGAPCHGVTGQCRCPPGRTGED 768
Query: 224 FECECPEGYRYNLKSK----SCEDIDECSENMCAQLCV 257
E +CPEG R+ L + +C+ C A LC+
Sbjct: 769 CEADCPEG-RWGLGCQEICPACQHAARCDPETGACLCL 805
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 33/128 (25%)
Query: 143 CTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDV 202
C C GW G C NE P CS + CSC+NG C V
Sbjct: 540 CDCPEGWTGLIC----NETCPPDTFGKNCS---------FSCSCQNG-------GTCDSV 579
Query: 203 -DECSLKPSICGTAVCKNIPGDFECECPEGY--RYNLKSKSCEDIDECSENMCAQLCVNY 259
C P + GT + E CP+GY ++ K +C + C A LC
Sbjct: 580 TGACRCPPGVSGT--------NCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLC--D 629
Query: 260 PGGYTCYC 267
PG Y +C
Sbjct: 630 PGLYGRFC 637
Score = 39.7 bits (91), Expect = 0.009
Identities = 42/166 (25%), Positives = 62/166 (37%), Gaps = 30/166 (18%)
Query: 133 SCKDG----KASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT----PGSYHC 184
SC++G ++ +C+C GW G CE + + + CS C N P + C
Sbjct: 1306 SCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECS--CHNNSTCEPATGTC 1363
Query: 185 SCKNGFVMLSNKKDCKDVDECSLKPSICGT---AVCKNIPGDFECECPEGYRYNLKSKSC 241
C GF + + C + +C A C I G C CP G+ + + C
Sbjct: 1364 RCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISG--RCLCPAGFHGHFCERGC 1421
Query: 242 E--DIDECSENMC-----------AQLCVNYPG--GYTCYCDGKKG 272
E E C LC+ PG G TC D ++G
Sbjct: 1422 EPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRG 1467
Score = 38.1 bits (87), Expect = 0.027
Identities = 41/159 (25%), Positives = 56/159 (35%), Gaps = 25/159 (15%)
Query: 139 ASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPG------SYHCSCKNGFVM 192
A+ TC+C G+ G C+ C P GC Q+C G + C C GF+
Sbjct: 1187 ATGTCSCAAGYHGPSCQ---QRC-PPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLG 1242
Query: 193 LSNKKDCKDVDECSLKPSICGT---AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE 249
C +CG A C + G C CP G R ++ CE C +
Sbjct: 1243 TDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLCPPG-RAGVR---CE--RGCPQ 1294
Query: 250 NM----CAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEV 284
N C C GG +G L + CE+
Sbjct: 1295 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCEL 1333
Score = 37.7 bits (86), Expect = 0.035
Identities = 40/149 (26%), Positives = 51/149 (34%), Gaps = 39/149 (26%)
Query: 143 CTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGS--YH----CSCKNGFVML--- 193
C C GW G+KC+ + C C+Q C PG+ +H C C GF
Sbjct: 1104 CLCPAGWTGDKCQ---SPCL-RGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE 1159
Query: 194 ------SNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDEC 247
S +DC + +C + C P C C GY SC+ C
Sbjct: 1160 QACPPGSFGEDCAQMCQCPGENPACH-------PATGTCSCAAGYH----GPSCQ--QRC 1206
Query: 248 SENM----CAQLCVNYPGGYTCYCDGKKG 272
C QLC GG CD G
Sbjct: 1207 PPGRYGPGCEQLCGCLNGG---SCDAATG 1232
Score = 37.0 bits (84), Expect = 0.060
Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 17/117 (14%)
Query: 124 LPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQIC------DN 177
L C+ +C+ A+ TC C PG+ G+ CE + C P GC +C
Sbjct: 1346 LECSCHNNSTCEP--ATGTCRCGPGFYGQACE---HPC-PPGFHGAGCQGLCWCQHGAPC 1399
Query: 178 TPGSYHCSCKNGFVMLSNKKDCKD---VDECSLKPSICGTAVCKNIPGDFECECPEG 231
P S C C GF ++ C+ + C + G A C + G C CP G
Sbjct: 1400 DPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG--LCLCPPG 1454
Score = 36.2 bits (82), Expect = 0.10
Identities = 37/145 (25%), Positives = 54/145 (37%), Gaps = 34/145 (23%)
Query: 143 CTCKPGWQGEKCEFDINECKDPSNINGGCSQI---CDNT----PGSYHCSCKNGFVMLSN 195
C C PG+ G +C+ + C P+ G Q C N P + HCSC G+ S
Sbjct: 802 CLCLPGFVGSRCQ---DVC--PAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSC 856
Query: 196 KK---------DCKDVDECSLKPSIC----GTAVCK--NIPGDFECECPEGYRYNLKSKS 240
++ DC CS C G +C+ + E +CP+G+
Sbjct: 857 QRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGH----FGPG 912
Query: 241 CEDIDECSENMCAQLCVNYPGGYTC 265
CE +C C + G TC
Sbjct: 913 CEQRCQCQHGAA---CDHVSGACTC 934
Score = 36.2 bits (82), Expect = 0.10
Identities = 45/171 (26%), Positives = 62/171 (36%), Gaps = 35/171 (20%)
Query: 134 CKDGKA----SFTCTCKPGWQGEKCE------FDINECKDPSNINGGCSQICDNTPGSYH 183
C+ G A S CTC GW+G CE F +C+ N G + CD GS
Sbjct: 919 CQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAA--CDAVNGS-- 974
Query: 184 CSCKNGFVMLSNKKDCKD---VDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS 240
C C G + C CS + A C + G +C C G+ S
Sbjct: 975 CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGW----MGPS 1028
Query: 241 CEDIDECSENM----CAQLCVNYPGGYTC-----YCDGKKGFKLAQDQKSC 282
C + C + C C+ GG TC +C +G+ +K C
Sbjct: 1029 C--LQACPAGLYGDNCRHSCLCQNGG-TCDPVSGHCACPEGWAGLACEKEC 1076
Score = 31.2 bits (69), Expect = 3.3
Identities = 29/101 (28%), Positives = 37/101 (36%), Gaps = 17/101 (16%)
Query: 142 TCTCKPGWQGEKCEFDINECKDPSNING-GCSQICDNTPGSY------HCSCKNGFVMLS 194
TC C PG G +CE C P N G GC C G CSC G+
Sbjct: 1276 TCLCPPGRAGVRCE---RGC--PQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRH 1330
Query: 195 NKKDC---KDVDECSLKPSICGTAVCKNIPGDFECECPEGY 232
+ C + C L+ S + C+ P C C G+
Sbjct: 1331 CELACPPGRYGAACHLECSCHNNSTCE--PATGTCRCGPGF 1369
Score = 30.4 bits (67), Expect = 5.6
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 4/68 (5%)
Query: 126 CNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECK-DPS-NINGGCSQICDNTPGSYH 183
C+ DG C + C C PG G C D + PS ++ C D P S
Sbjct: 1434 CDCDGGAPCDP--VTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQ 1491
Query: 184 CSCKNGFV 191
C C +G++
Sbjct: 1492 CHCVDGYM 1499
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 113 bits (282), Expect = 7e-25
Identities = 60/167 (35%), Positives = 93/167 (55%), Gaps = 16/167 (9%)
Query: 133 SCKDGKASFTC-----TCKPGW----QGEKCEFDINECKDPSNINGGCSQICDNTPGSYH 183
+C + + S+TC C G+ +G +C D++EC P+ G + C N+PGS+
Sbjct: 324 TCINTEGSYTCQKNVPNCGRGYHLNEEGTRC-VDVDECAPPAEPCGKGHR-CVNSPGSFR 381
Query: 184 CSCKNGFVMLSNKKDCKDVDECSLKPS-ICGTAVCKNIPGDFECECPEGYRYNLKSKSCE 242
C CK G+ + C DV+EC P +CG C+N G + C C G+R ++ +SCE
Sbjct: 382 CECKTGYYFDGISRMCVDVNECQRYPGRLCGHK-CENTLGSYLCSCSVGFRLSVDGRSCE 440
Query: 243 DIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQ-DQKSCEVVSVC 288
DI+ECS + C+Q C N G Y CYC ++G++L+ D +CE + C
Sbjct: 441 DINECSSSPCSQECANVYGSYQCYC--RRGYQLSDVDGVTCEDIDEC 485
Score = 89.0 bits (219), Expect = 1e-17
Identities = 62/172 (36%), Positives = 85/172 (49%), Gaps = 27/172 (15%)
Query: 109 DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ-----GEKCEFDINECKD 163
D RSC + ++CS PC+++ C + S+ C C+ G+Q G CE DI+EC
Sbjct: 435 DGRSCEDI--NECSSSPCSQE----CANVYGSYQCYCRRGYQLSDVDGVTCE-DIDECAL 487
Query: 164 PSNINGG--CSQICDNTPGSYHCSC-KNGFVMLSNKKDCKDVDECSLKPSICG-TAVCKN 219
P+ GG CS C N PGS+ CSC +G+ + N ++C+D+DEC C C N
Sbjct: 488 PT---GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFN 544
Query: 220 IPGDFEC---ECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCD 268
I G F C ECPE YR + + E D C + C P TC D
Sbjct: 545 IQGGFRCLAFECPENYRRSAATLQQEKTDTV---RCIKSC--RPNDVTCVFD 591
Score = 61.6 bits (148), Expect = 2e-09
Identities = 43/135 (31%), Positives = 61/135 (45%), Gaps = 13/135 (9%)
Query: 169 GGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTA-VCKNIPGDFECE 227
G C Q C +T CSC G+ +LS+ C+DV+EC C C N G F C+
Sbjct: 184 GPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 228 ----CPEGYRYNLKSKSCEDIDECSENM--CAQ--LCVNYPGGYTC--YCDGKKGFKLAQ 277
C GY + SC+DIDEC + C +C N G + C K GF +
Sbjct: 244 RDSSCGTGYELT-EDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGF-IQD 301
Query: 278 DQKSCEVVSVCLPLN 292
+C ++ CL ++
Sbjct: 302 ALGNCIDINECLSIS 316
>gi|7382460 sex hormone-binding globulin isoform 1 precursor [Homo
sapiens]
Length = 402
Score = 107 bits (268), Expect = 3e-23
Identities = 98/362 (27%), Positives = 174/362 (48%), Gaps = 30/362 (8%)
Query: 310 VLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTS 369
+ + F L +I++ S+ F+ RT+D EGVI Y ++ W ++ LR G+ E+QL N H +
Sbjct: 56 IAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHN-HWA 114
Query: 370 KITTG-GDVINNGLWNMVSVEELEHSISIKIAKEAVMDINK-PGPLFKPENGLLETKVYF 427
++T G G +++G W+ V V+ S+ +++ E V+ + + GPL + ++ +
Sbjct: 115 QLTVGAGPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGG 174
Query: 428 AGFPRKVESELIKPINPRLDGCIR--SWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYY 485
FP S L P+ P LDGC+R SW L KQ + C V G +
Sbjct: 175 LLFP---ASNLRLPLVPALDGCLRRDSW-LDKQAEISAS---APTSLRSCDVESNPGIFL 227
Query: 486 PGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLVDSTSE 545
P A+F++ AE W ++ L ++ + G+G +LAL + N ++ L D
Sbjct: 228 PPGTQAEFNLRDIPQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQD---- 283
Query: 546 KSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQRQLA 605
Q ++LS + L L L+ +++ + + LS K++ ++ L
Sbjct: 284 --QKVVLSSGSG-----PGLDLPLVLGLPLQLKLSMSRVVLSQGSKMKALALPPL-GLAP 335
Query: 606 VLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHS 665
+L+ K + +LG LP S + NG G +LD+D+A+++ ++I HS
Sbjct: 336 LLNLWAKPQGRLFLGALPGEDSS---TSFCLNGLW---AQGQRLDVDQALNRSHEIWTHS 389
Query: 666 CP 667
CP
Sbjct: 390 CP 391
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 107 bits (266), Expect = 5e-23
Identities = 61/189 (32%), Positives = 99/189 (52%), Gaps = 18/189 (9%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKD 163
PD + C + D+C +G CK+ + SF CTC G+Q ++CE DI+EC+
Sbjct: 1073 PDHKHCRDI--DECQQGNLCVNG--QCKNTEGSFRCTCGQGYQLSAAKDQCE-DIDECQH 1127
Query: 164 PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGD 223
G C NT GS+ C C G+ C+D++EC S+C C N G
Sbjct: 1128 RHLCAHGQ---CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGS 1184
Query: 224 FECECPEGYRYNLKSKSCEDIDECSE-NMCAQL--CVNYPGGYTCYCDGKKGFKLAQDQK 280
++C CP+G++ + +K+C+DI+EC +C C+N G + C C ++GF ++ D +
Sbjct: 1185 YDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVC--QQGFSISADGR 1241
Query: 281 SCEVVSVCL 289
+CE + C+
Sbjct: 1242 TCEDIDECV 1250
Score = 104 bits (259), Expect = 3e-22
Identities = 68/196 (34%), Positives = 97/196 (49%), Gaps = 21/196 (10%)
Query: 97 FTAARQSTNAYPDLRSCVNAIPDQCSPLPC-NEDGYMSCKDGKASFTCTCKPGWQGEKCE 155
F A+ + TN D+ C+ PD C C N G C+ + + T Q +CE
Sbjct: 947 FMASEEGTNCI-DVDECLR--PDVCGEGHCVNTVGAFRCEYCDSGYRMT-----QRGRCE 998
Query: 156 FDINECKDPSNINGGCSQICDNTPGSYHC-SCKNGFVMLSNKKDCKDVDECSLKPSICGT 214
DI+EC +PS + C N+PGSY C C GF + + C DVDEC L+P++C
Sbjct: 999 -DIDECLNPSTCP---DEQCVNSPGSYQCVPCTEGFRGWNGQ--CLDVDEC-LEPNVCAN 1051
Query: 215 AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-NMCAQ-LCVNYPGGYTCYCDGKKG 272
C N+ G + C C +GY K C DIDEC + N+C C N G + C C +G
Sbjct: 1052 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG--QG 1109
Query: 273 FKLAQDQKSCEVVSVC 288
++L+ + CE + C
Sbjct: 1110 YQLSAAKDQCEDIDEC 1125
Score = 98.6 bits (244), Expect = 2e-20
Identities = 68/193 (35%), Positives = 96/193 (49%), Gaps = 25/193 (12%)
Query: 111 RSCVNAIPDQCSPLP--CNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFDINECKDP 164
R CV+ D+C+ + C++ C++ + SF C C G+ +G C D++EC P
Sbjct: 912 RKCVDI--DECTQVQHLCSQG---RCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRP 965
Query: 165 SNINGGCSQICDNTPGSYHCS-CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGD 223
G C NT G++ C C +G+ M + C+D+DEC L PS C C N PG
Sbjct: 966 DVCGEGH---CVNTVGAFRCEYCDSGYRMTQRGR-CEDIDEC-LNPSTCPDEQCVNSPGS 1020
Query: 224 FEC-ECPEGYRYNLKSKSCEDIDECSE-NMCAQL-CVNYPGGYTCYCDGKKGFKLAQDQK 280
++C C EG+R + C D+DEC E N+CA C N G Y C C KG+ D K
Sbjct: 1021 YQCVPCTEGFRG--WNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCH--KGYTRTPDHK 1076
Query: 281 SCEVVSVCLPLNL 293
C + C NL
Sbjct: 1077 HCRDIDECQQGNL 1089
Score = 94.7 bits (234), Expect = 2e-19
Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 16/165 (9%)
Query: 115 NAIPDQCSPL-PCNEDGYM----SCKDGKASFTCTCKPGWQ---GEKCEFDINECKDPSN 166
+ + D C + C ED + C + S+ CTC G+Q + C+ DINEC+ P
Sbjct: 1154 SGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGL 1212
Query: 167 INGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFE 225
G C NT GS+HC C+ GF + ++ + C+D+DEC + ++C + C N G F
Sbjct: 1213 C--GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFR 1269
Query: 226 CECPEGYRYNLKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYC 267
C C +G++ + C D++EC +C + C N G + C C
Sbjct: 1270 CLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 1314
Score = 86.7 bits (213), Expect = 7e-17
Identities = 47/136 (34%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
+INEC +I G C N P Y C C G+ ++ C D+DEC+ +C
Sbjct: 874 EINECTVNPDICGAGH--CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR 931
Query: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTC-YCDGKKGF 273
C+N G F C CP G+ + + +C D+DEC ++C + CVN G + C YCD G+
Sbjct: 932 CENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCD--SGY 989
Query: 274 KLAQDQKSCEVVSVCL 289
++ Q + CE + CL
Sbjct: 990 RMTQ-RGRCEDIDECL 1004
Score = 80.1 bits (196), Expect = 6e-15
Identities = 54/157 (34%), Positives = 73/157 (46%), Gaps = 31/157 (19%)
Query: 126 CNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ--ICDNTP 179
C G C + + SF C C+ G+ G CE DI+EC + N C CDNT
Sbjct: 1213 CGPQG--ECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVN----NTVCDSHGFCDNTA 1265
Query: 180 GSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECEC-PEGYRYN--- 235
GS+ C C GF + + C DV+EC L +CG A C+N+ G F C C E Y+
Sbjct: 1266 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT 1325
Query: 236 --LKSKSCEDID-----------ECSENM-CAQLCVN 258
+S++ D+D EC N+ A LC N
Sbjct: 1326 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDN 1362
Score = 57.4 bits (137), Expect = 4e-08
Identities = 40/133 (30%), Positives = 52/133 (39%), Gaps = 11/133 (8%)
Query: 138 KASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKK 197
K CT GW G+ CE + C + P S G +
Sbjct: 1370 KQECCCTSGAGW-GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG-------E 1421
Query: 198 DCKDVDECSL-KPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-NMCAQ- 254
+ KD DEC L IC C N +EC C +G Y+ C D+DEC + + C
Sbjct: 1422 NYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDG 1481
Query: 255 LCVNYPGGYTCYC 267
CVN G Y C+C
Sbjct: 1482 QCVNTEGSYNCFC 1494
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/145 (23%), Positives = 64/145 (44%), Gaps = 17/145 (11%)
Query: 134 CKDGKASFTCTCKPGWQGEKCE---FDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
C + + + C CK G + + FD++EC+DPS+ G C NT GSY+C C +
Sbjct: 1442 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQ---CVNTEGSYNCFCTHPM 1498
Query: 191 VMLSNKKDC-------KDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
V+ +++K C + ++E + +C +++ ++ C P + ++ C
Sbjct: 1499 VLDASEKRCIRPAESNEQIEETDVYQDLC----WEHLSDEYVCSRPLVGKQTTYTECCCL 1554
Query: 244 IDECSENMCAQLCVNYPGGYTCYCD 268
E CA + Y C+
Sbjct: 1555 YGEAWGMQCALCPLKDSDDYAQLCN 1579
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 13/99 (13%)
Query: 150 QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDEC---S 206
Q E+C +N C+ NG C ++ + Y C C +G+ + + K C DV+EC +
Sbjct: 1622 QAEECGI-LNGCE-----NGRCVRVQEG----YTCDCFDGYHLDTAKMTCVDVNECDELN 1671
Query: 207 LKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245
+ S+C A C N G ++C C GY + K C ++
Sbjct: 1672 NRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1710
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 9/102 (8%)
Query: 203 DECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-----NMCAQL-C 256
+EC + C C + + C+C +GY + +C D++EC E ++C C
Sbjct: 1624 EECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKC 1682
Query: 257 VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYE 298
+N G Y C C G+ + C ++ L L D+ E
Sbjct: 1683 INTDGSYKCLC--LPGYVPSDKPNYCTPLNTALNLEKDSDLE 1722
Score = 38.5 bits (88), Expect = 0.021
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 173 QICDNTPGSYH-----CSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Q C P SYH C G+ ++N C+D++EC L+ +C C N G + C
Sbjct: 595 QKCPKKP-SYHGYNQMMECLPGYKRVNNTF-CQDINECQLQ-GVCPNGECLNTMGSYRCT 651
Query: 228 CPEGYRYNLKSKSC 241
C G+ + SC
Sbjct: 652 CKIGFGPDPTFSSC 665
Score = 37.7 bits (86), Expect = 0.035
Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query: 145 CKPGWQGEKCEF--DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGF 190
C PG++ F DINEC+ + G C C NT GSY C+CK GF
Sbjct: 612 CLPGYKRVNNTFCQDINECQ----LQGVCPNGECLNTMGSYRCTCKIGF 656
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 107 bits (266), Expect = 5e-23
Identities = 61/189 (32%), Positives = 99/189 (52%), Gaps = 18/189 (9%)
Query: 108 PDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKD 163
PD + C + D+C +G CK+ + SF CTC G+Q ++CE DI+EC+
Sbjct: 747 PDHKHCRDI--DECQQGNLCVNG--QCKNTEGSFRCTCGQGYQLSAAKDQCE-DIDECQH 801
Query: 164 PSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGD 223
G C NT GS+ C C G+ C+D++EC S+C C N G
Sbjct: 802 RHLCAHGQ---CRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGS 858
Query: 224 FECECPEGYRYNLKSKSCEDIDECSE-NMCAQL--CVNYPGGYTCYCDGKKGFKLAQDQK 280
++C CP+G++ + +K+C+DI+EC +C C+N G + C C ++GF ++ D +
Sbjct: 859 YDCTCPDGFQLD-DNKTCQDINECEHPGLCGPQGECLNTEGSFHCVC--QQGFSISADGR 915
Query: 281 SCEVVSVCL 289
+CE + C+
Sbjct: 916 TCEDIDECV 924
Score = 104 bits (259), Expect = 3e-22
Identities = 68/196 (34%), Positives = 97/196 (49%), Gaps = 21/196 (10%)
Query: 97 FTAARQSTNAYPDLRSCVNAIPDQCSPLPC-NEDGYMSCKDGKASFTCTCKPGWQGEKCE 155
F A+ + TN D+ C+ PD C C N G C+ + + T Q +CE
Sbjct: 621 FMASEEGTNCI-DVDECLR--PDVCGEGHCVNTVGAFRCEYCDSGYRMT-----QRGRCE 672
Query: 156 FDINECKDPSNINGGCSQICDNTPGSYHC-SCKNGFVMLSNKKDCKDVDECSLKPSICGT 214
DI+EC +PS + C N+PGSY C C GF + + C DVDEC L+P++C
Sbjct: 673 -DIDECLNPSTCP---DEQCVNSPGSYQCVPCTEGFRGWNGQ--CLDVDEC-LEPNVCAN 725
Query: 215 AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-NMCAQ-LCVNYPGGYTCYCDGKKG 272
C N+ G + C C +GY K C DIDEC + N+C C N G + C C +G
Sbjct: 726 GDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG--QG 783
Query: 273 FKLAQDQKSCEVVSVC 288
++L+ + CE + C
Sbjct: 784 YQLSAAKDQCEDIDEC 799
Score = 98.6 bits (244), Expect = 2e-20
Identities = 68/193 (35%), Positives = 96/193 (49%), Gaps = 25/193 (12%)
Query: 111 RSCVNAIPDQCSPLP--CNEDGYMSCKDGKASFTCTCKPGW----QGEKCEFDINECKDP 164
R CV+ D+C+ + C++ C++ + SF C C G+ +G C D++EC P
Sbjct: 586 RKCVDI--DECTQVQHLCSQG---RCENTEGSFLCICPAGFMASEEGTNC-IDVDECLRP 639
Query: 165 SNINGGCSQICDNTPGSYHCS-CKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGD 223
G C NT G++ C C +G+ M + C+D+DEC L PS C C N PG
Sbjct: 640 DVCGEGH---CVNTVGAFRCEYCDSGYRMTQRGR-CEDIDEC-LNPSTCPDEQCVNSPGS 694
Query: 224 FEC-ECPEGYRYNLKSKSCEDIDECSE-NMCAQL-CVNYPGGYTCYCDGKKGFKLAQDQK 280
++C C EG+R + C D+DEC E N+CA C N G Y C C KG+ D K
Sbjct: 695 YQCVPCTEGFRG--WNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCH--KGYTRTPDHK 750
Query: 281 SCEVVSVCLPLNL 293
C + C NL
Sbjct: 751 HCRDIDECQQGNL 763
Score = 94.7 bits (234), Expect = 2e-19
Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 16/165 (9%)
Query: 115 NAIPDQCSPL-PCNEDGYM----SCKDGKASFTCTCKPGWQ---GEKCEFDINECKDPSN 166
+ + D C + C ED + C + S+ CTC G+Q + C+ DINEC+ P
Sbjct: 828 SGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQ-DINECEHPGL 886
Query: 167 INGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGT-AVCKNIPGDFE 225
G C NT GS+HC C+ GF + ++ + C+D+DEC + ++C + C N G F
Sbjct: 887 C--GPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC-VNNTVCDSHGFCDNTAGSFR 943
Query: 226 CECPEGYRYNLKSKSCEDIDECS--ENMCAQ-LCVNYPGGYTCYC 267
C C +G++ + C D++EC +C + C N G + C C
Sbjct: 944 CLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVC 988
Score = 86.7 bits (213), Expect = 7e-17
Identities = 47/136 (34%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 157 DINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAV 216
+INEC +I G C N P Y C C G+ ++ C D+DEC+ +C
Sbjct: 548 EINECTVNPDICGAGH--CINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGR 605
Query: 217 CKNIPGDFECECPEGYRYNLKSKSCEDIDEC-SENMCAQ-LCVNYPGGYTC-YCDGKKGF 273
C+N G F C CP G+ + + +C D+DEC ++C + CVN G + C YCD G+
Sbjct: 606 CENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCD--SGY 663
Query: 274 KLAQDQKSCEVVSVCL 289
++ Q + CE + CL
Sbjct: 664 RMTQ-RGRCEDIDECL 678
Score = 80.1 bits (196), Expect = 6e-15
Identities = 54/157 (34%), Positives = 73/157 (46%), Gaps = 31/157 (19%)
Query: 126 CNEDGYMSCKDGKASFTCTCKPGWQ----GEKCEFDINECKDPSNINGGCSQ--ICDNTP 179
C G C + + SF C C+ G+ G CE DI+EC + N C CDNT
Sbjct: 887 CGPQG--ECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVN----NTVCDSHGFCDNTA 939
Query: 180 GSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECEC-PEGYRYN--- 235
GS+ C C GF + + C DV+EC L +CG A C+N+ G F C C E Y+
Sbjct: 940 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT 999
Query: 236 --LKSKSCEDID-----------ECSENM-CAQLCVN 258
+S++ D+D EC N+ A LC N
Sbjct: 1000 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDN 1036
Score = 57.4 bits (137), Expect = 4e-08
Identities = 40/133 (30%), Positives = 52/133 (39%), Gaps = 11/133 (8%)
Query: 138 KASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKK 197
K CT GW G+ CE + C + P S G +
Sbjct: 1044 KQECCCTSGAGW-GDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGG-------E 1095
Query: 198 DCKDVDECSL-KPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-NMCAQ- 254
+ KD DEC L IC C N +EC C +G Y+ C D+DEC + + C
Sbjct: 1096 NYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDG 1155
Query: 255 LCVNYPGGYTCYC 267
CVN G Y C+C
Sbjct: 1156 QCVNTEGSYNCFC 1168
Score = 49.3 bits (116), Expect = 1e-05
Identities = 34/145 (23%), Positives = 64/145 (44%), Gaps = 17/145 (11%)
Query: 134 CKDGKASFTCTCKPGWQGEKCE---FDINECKDPSNINGGCSQICDNTPGSYHCSCKNGF 190
C + + + C CK G + + FD++EC+DPS+ G C NT GSY+C C +
Sbjct: 1116 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQ---CVNTEGSYNCFCTHPM 1172
Query: 191 VMLSNKKDC-------KDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCED 243
V+ +++K C + ++E + +C +++ ++ C P + ++ C
Sbjct: 1173 VLDASEKRCIRPAESNEQIEETDVYQDLC----WEHLSDEYVCSRPLVGKQTTYTECCCL 1228
Query: 244 IDECSENMCAQLCVNYPGGYTCYCD 268
E CA + Y C+
Sbjct: 1229 YGEAWGMQCALCPLKDSDDYAQLCN 1253
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 13/99 (13%)
Query: 150 QGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDEC---S 206
Q E+C +N C+ NG C ++ + Y C C +G+ + + K C DV+EC +
Sbjct: 1296 QAEECGI-LNGCE-----NGRCVRVQEG----YTCDCFDGYHLDTAKMTCVDVNECDELN 1345
Query: 207 LKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDID 245
+ S+C A C N G ++C C GY + K C ++
Sbjct: 1346 NRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLN 1384
Score = 47.8 bits (112), Expect = 3e-05
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 9/102 (8%)
Query: 203 DECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE-----NMCAQL-C 256
+EC + C C + + C+C +GY + +C D++EC E ++C C
Sbjct: 1298 EECGILNG-CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKC 1356
Query: 257 VNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYE 298
+N G Y C C G+ + C ++ L L D+ E
Sbjct: 1357 INTDGSYKCLC--LPGYVPSDKPNYCTPLNTALNLEKDSDLE 1396
Score = 38.5 bits (88), Expect = 0.021
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 8/74 (10%)
Query: 173 QICDNTPGSYH-----CSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECE 227
Q C P SYH C G+ ++N C+D++EC L+ +C C N G + C
Sbjct: 269 QKCPKKP-SYHGYNQMMECLPGYKRVNNTF-CQDINECQLQ-GVCPNGECLNTMGSYRCT 325
Query: 228 CPEGYRYNLKSKSC 241
C G+ + SC
Sbjct: 326 CKIGFGPDPTFSSC 339
Score = 37.7 bits (86), Expect = 0.035
Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query: 145 CKPGWQGEKCEF--DINECKDPSNINGGCSQ-ICDNTPGSYHCSCKNGF 190
C PG++ F DINEC+ + G C C NT GSY C+CK GF
Sbjct: 286 CLPGYKRVNNTFCQDINECQ----LQGVCPNGECLNTMGSYRCTCKIGF 330
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,410,572
Number of Sequences: 37866
Number of extensions: 1324597
Number of successful extensions: 7292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 3259
Number of HSP's gapped (non-prelim): 1776
length of query: 676
length of database: 18,247,518
effective HSP length: 109
effective length of query: 567
effective length of database: 14,120,124
effective search space: 8006110308
effective search space used: 8006110308
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.