BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|190014607 netrin G2 [Homo sapiens] (530 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|190014607 netrin G2 [Homo sapiens] 1156 0.0 gi|164414431 netrin G1 isoform 1 [Homo sapiens] 691 0.0 gi|164414437 netrin G1 isoform 2 [Homo sapiens] 444 e-124 gi|54312078 netrin G1 isoform 3 [Homo sapiens] 440 e-123 gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 209 7e-54 gi|148613884 netrin 1 [Homo sapiens] 204 1e-52 gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 197 3e-50 gi|5453810 netrin 3 [Homo sapiens] 194 1e-49 gi|21264602 laminin alpha 5 [Homo sapiens] 189 5e-48 gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 169 8e-42 gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 169 8e-42 gi|143770880 laminin, beta 4 [Homo sapiens] 167 2e-41 gi|93204871 netrin 4 [Homo sapiens] 162 7e-40 gi|119703755 laminin, beta 2 precursor [Homo sapiens] 158 1e-38 gi|62868217 laminin, beta 3 precursor [Homo sapiens] 152 1e-36 gi|62868215 laminin, beta 3 precursor [Homo sapiens] 152 1e-36 gi|189083719 laminin, beta 3 precursor [Homo sapiens] 152 1e-36 gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 147 3e-35 gi|167614504 laminin, beta 1 precursor [Homo sapiens] 142 6e-34 gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 134 2e-31 gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 134 2e-31 gi|219842266 usherin isoform B [Homo sapiens] 126 4e-29 gi|219842259 usherin isoform A [Homo sapiens] 126 4e-29 gi|24308065 netrin 5 [Homo sapiens] 115 1e-25 gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 97 3e-20 gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 97 3e-20 gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 96 1e-19 gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 75 1e-13 gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 75 2e-13 gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 75 2e-13 >gi|190014607 netrin G2 [Homo sapiens] Length = 530 Score = 1156 bits (2991), Expect = 0.0 Identities = 530/530 (100%), Positives = 530/530 (100%) Query: 1 MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGIT 60 MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGIT Sbjct: 1 MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGIT 60 Query: 61 CGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLE 120 CGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLE Sbjct: 61 CGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLE 120 Query: 121 ANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSAR 180 ANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSAR Sbjct: 121 ANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSAR 180 Query: 181 RARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESA 240 RARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESA Sbjct: 181 RARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESA 240 Query: 241 KGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE 300 KGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE Sbjct: 241 KGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE 300 Query: 301 GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSN 360 GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSN Sbjct: 301 GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSN 360 Query: 361 RCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 420 RCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR Sbjct: 361 RCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 420 Query: 421 CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRG 480 CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRG Sbjct: 421 CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRG 480 Query: 481 YTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR 530 YTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR Sbjct: 481 YTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR 530 >gi|164414431 netrin G1 isoform 1 [Homo sapiens] Length = 539 Score = 691 bits (1782), Expect = 0.0 Identities = 311/519 (59%), Positives = 384/519 (73%), Gaps = 8/519 (1%) Query: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72 PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+ Sbjct: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83 Query: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132 NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E Sbjct: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143 Query: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192 LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S + Sbjct: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203 Query: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252 ++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL Sbjct: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262 Query: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312 R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT Sbjct: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322 Query: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECYGHSNRCSYIDFLNVV 371 GPDCGKCKKN++ R W GSYLP+P G+ N C + S GNCEC+GHSNRCSYID LN V Sbjct: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTV 382 Query: 372 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECRE 431 CVSCKHNTRGQHC+ CRLGY+RN SA+LDDENVCIEC CN +GS+HDRCN +GFCEC+ Sbjct: 383 ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKT 442 Query: 432 GAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRC 491 G GPKCD+CLP + W GC PNVCD++ L CQNGGTC N RC CP YTG+ CE+ RC Sbjct: 443 GTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRC 502 Query: 492 DPADDDGGLDCDRAPGAAPR--PATLLGCLLLLGLAARL 528 + A G D GA P PA LL LLG A+ L Sbjct: 503 EEA---GSCGSDSGQGAPPHGSPALLL-LTTLLGTASPL 537 >gi|164414437 netrin G1 isoform 2 [Homo sapiens] Length = 480 Score = 444 bits (1141), Expect = e-124 Identities = 215/439 (48%), Positives = 284/439 (64%), Gaps = 19/439 (4%) Query: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72 PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+ Sbjct: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83 Query: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132 NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E Sbjct: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143 Query: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192 LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S + Sbjct: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203 Query: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252 ++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL Sbjct: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262 Query: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312 R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT Sbjct: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322 Query: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECY------------GHS 359 GPDCGKCKKN++ R W GSYLP+P G+ N C + S GN + + Sbjct: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNPPKFNRIWPNISSLEVSNP 382 Query: 360 NRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHD 419 + + L+ V+ V ++ R C + L G+ NV C G + + Sbjct: 383 KQVAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGTCH---NNVRCLCPAAYTGILCE 439 Query: 420 --RCNETGFCECREGAAGP 436 RC E G C G P Sbjct: 440 KLRCEEAGSCGSDSGQGAP 458 Score = 78.6 bits (192), Expect = 1e-14 Identities = 66/192 (34%), Positives = 87/192 (45%), Gaps = 22/192 (11%) Query: 351 GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGY----YRNGS---AELDDE 403 G C+C H+ C Y + + +TC C+HNT G C C+ Y + GS Sbjct: 295 GRCKCNLHATVCVYDN--SKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTA 351 Query: 404 NVCIECNCNQIGSV--HDRC--NETGFCECREGAAGPKCD-DCLPTHYWRQGCYPNVCDD 458 N CI + + IG+ +R N + PK + + NVCD+ Sbjct: 352 NTCIP-SISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDN 410 Query: 459 DQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPR--PATLL 516 + L CQNGGTC N RC CP YTG+ CE+ RC+ A G D GA P PA LL Sbjct: 411 ELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEA---GSCGSDSGQGAPPHGSPALLL 467 Query: 517 GCLLLLGLAARL 528 LLG A+ L Sbjct: 468 -LTTLLGTASPL 478 Score = 31.6 bits (70), Expect = 1.9 Identities = 17/56 (30%), Positives = 20/56 (35%), Gaps = 3/56 (5%) Query: 400 LDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY---WRQGCY 452 + D V C CN +V N CEC GP C C + W G Y Sbjct: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343 >gi|54312078 netrin G1 isoform 3 [Homo sapiens] Length = 438 Score = 440 bits (1132), Expect = e-123 Identities = 198/351 (56%), Positives = 255/351 (72%), Gaps = 2/351 (0%) Query: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72 PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+ Sbjct: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83 Query: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132 NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E Sbjct: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143 Query: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192 LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S + Sbjct: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203 Query: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252 ++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL Sbjct: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262 Query: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312 R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT Sbjct: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322 Query: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECYGHSNRC 362 GPDCGKCKKN++ R W GSYLP+P G+ N C + S G C C Sbjct: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGTNVCDNELLHC 373 Score = 85.5 bits (210), Expect = 1e-16 Identities = 56/153 (36%), Positives = 65/153 (42%), Gaps = 28/153 (18%) Query: 400 LDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY---WRQGCY---- 452 + D V C CN +V N CEC GP C C + W G Y Sbjct: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP 347 Query: 453 ---------------PNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDD 497 NVCD++ L CQNGGTC N RC CP YTG+ CE+ RC+ A Sbjct: 348 KGTANTCIPSISSIGTNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEA--- 404 Query: 498 GGLDCDRAPGAAPR--PATLLGCLLLLGLAARL 528 G D GA P PA LL LLG A+ L Sbjct: 405 GSCGSDSGQGAPPHGSPALLL-LTTLLGTASPL 436 >gi|145309326 laminin, gamma 1 precursor [Homo sapiens] Length = 1609 Score = 209 bits (531), Expect = 7e-54 Identities = 151/482 (31%), Positives = 207/482 (42%), Gaps = 59/482 (12%) Query: 28 TDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHENPYLCSNEC---DAS 84 TDEG + C P+ + V V TCG PPE +C + C DA Sbjct: 41 TDEGGRPQ--RCMPEFVNAAFNVTVVATN---TCGTPPEEYCVQTGVTGVTKSCHLCDAG 95 Query: 85 NPDLAHPPRLMFDKEEEGLATYWQSITWS---RYPSPLEANITLSWNKTVELTDDVVMTF 141 P L H + D + T+WQS T +YPS + N+TL K ++T V + F Sbjct: 96 QPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSI--NLTLHLGKAFDITY-VRLKF 152 Query: 142 EYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHRVLCTEEYSR 201 RP + K W PYQ+Y+ C + A R + + LCT+E+S Sbjct: 153 HTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYS-KANRGFIRTGGDEQQALCTDEFSD 211 Query: 202 WAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLLRPAL 261 +V F + P N DN + L+E+ T TD+R+ L R Sbjct: 212 -ISPLTGGNVAFSTLE-----GRPSAYNFDN-------SPVLQEWVTATDIRVTLNRLNT 258 Query: 262 GGTYVQREN--LYKYFYAISNIEVIGRCKCNLHANLCSMRE-GSLQCECEHNTTGPDCGK 318 G V + L Y+YAIS+ V GRCKCN HA+ C E L C C+HNT G DC K Sbjct: 259 FGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEK 318 Query: 319 CKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVT-----C 373 C F R WR + +A C+C G S C + L T C Sbjct: 319 CLPFFNDRPWRRAT-----------AESASECLPCDCNGRSQECYFDPELYRSTGHGGHC 367 Query: 374 VSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGA 433 +C+ NT G HC+ CR ++R G+ E C C+C+ +GS+ +C+ G C C+ G Sbjct: 368 TNCQDNTDGAHCERCRENFFRLGNNE-----ACSSCHCSPVGSLSTQCDSYGRCSCKPGV 422 Query: 434 AGPKCDDCLPTHY--WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRC 491 G KCD C P + GC P CD + + ++ RC C G CE RC Sbjct: 423 MGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECN---IETGRCVCKDNVEGFNCE--RC 477 Query: 492 DP 493 P Sbjct: 478 KP 479 Score = 84.7 bits (208), Expect = 2e-16 Identities = 61/209 (29%), Positives = 85/209 (40%), Gaps = 29/209 (13%) Query: 286 RCKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPN 342 +C N+ N C+ G +C +NT G C +CK F P P Sbjct: 829 QCSDNIDPNAVGNCNRLTGEC-LKCIYNTAGFYCDRCKDGFF-----GNPLAPNPADKCK 882 Query: 343 ACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402 AC NC YG + S + V C + GQ C C G+Y L Sbjct: 883 AC-------NCNLYGTMKQQSSCN--PVTGQCECLPHVTGQDCGACDPGFYN-----LQS 928 Query: 403 ENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYW--RQGCYPNVCDDD 459 C C+C+ +GS + +C+ TG CEC+ G G C+ C H+ +GC P C + Sbjct: 929 GQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPE 988 Query: 460 QLLCQNGGTCLQNQRCACPRGYTGVRCEQ 488 L C + RC C G+ G RC+Q Sbjct: 989 GSLSLQ---CKDDGRCECREGFVGNRCDQ 1014 Score = 82.4 bits (202), Expect = 9e-16 Identities = 71/268 (26%), Positives = 91/268 (33%), Gaps = 84/268 (31%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C CN H+ C G C C NT GP C KC + +G A T Sbjct: 724 CACNGHSETCDPETGV--CNCRDNTAGPHCEKCSDGY--------------YGDSTA-GT 766 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYY-----RNGSAEL- 400 + C C G S+ C+ + V C +C T G+ C+ C GY+ RNG L Sbjct: 767 SSDCQPCPCPGGSS-CAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLC 825 Query: 401 --------------------------------------------------DDENVCIECN 410 + + C CN Sbjct: 826 RLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACN 885 Query: 411 CNQIGSVHDR--CNE-TGFCECREGAAGPKCDDCLPTHY---WRQGCYPNVCDDDQLLCQ 464 CN G++ + CN TG CEC G C C P Y QGC CD L Sbjct: 886 CNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGC--ERCDCHALGST 943 Query: 465 NGGTCLQNQRCACPRGYTGVRCEQPRCD 492 NG ++ +C C G TG CE RC+ Sbjct: 944 NGQCDIRTGQCECQPGITGQHCE--RCE 969 Score = 79.0 bits (193), Expect = 1e-14 Identities = 49/173 (28%), Positives = 72/173 (41%), Gaps = 36/173 (20%) Query: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSP 341 C CNL+ + C+ G QCEC + TG DCG C F S Sbjct: 884 CNCNLYGTMKQQSSCNPVTG--QCECLPHVTGQDCGACDPGFYNLQ------------SG 929 Query: 342 NACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELD 401 C C+C+ + D + C C+ GQHC+ C + ++ G Sbjct: 930 QGCE------RCDCHALGSTNGQCD-IRTGQC-ECQPGITGQHCERCEVNHFGFGPEG-- 979 Query: 402 DENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ---GC 451 C C+C+ GS+ +C + G CECREG G +CD C +++ + GC Sbjct: 980 ----CKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGC 1028 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/123 (31%), Positives = 49/123 (39%), Gaps = 10/123 (8%) Query: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECR 430 V +C GQ C+ C GY R + L + C+ C CN D ETG C CR Sbjct: 687 VESCTCPVGYGGQFCEMCLSGYRRE-TPNLGPYSPCVLCACNGHSETCDP--ETGVCNCR 743 Query: 431 EGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCA------CPRGYTGV 484 + AGP C+ C Y+ D C G +C + CP G TG Sbjct: 744 DNTAGPHCEKC-SDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGK 802 Query: 485 RCE 487 RCE Sbjct: 803 RCE 805 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/139 (27%), Positives = 50/139 (35%), Gaps = 23/139 (16%) Query: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364 C C G C C +R + G Y P C C C GHS C Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSP--------CVL------CACNGHSETCDP 735 Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC--NQIGSVHDRCN 422 C +C+ NT G HC+ C GYY + +A + C C C +V + Sbjct: 736 ----ETGVC-NCRDNTAGPHCEKCSDGYYGDSTAGTSSD--CQPCPCPGGSSCAVVPKTK 788 Query: 423 ETGFCECREGAAGPKCDDC 441 E C G G +C+ C Sbjct: 789 EVVCTNCPTGTTGKRCELC 807 >gi|148613884 netrin 1 [Homo sapiens] Length = 604 Score = 204 bits (520), Expect = 1e-52 Identities = 125/398 (31%), Positives = 190/398 (47%), Gaps = 45/398 (11%) Query: 60 TCGDPPERFC----SHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRY 115 TCG PP R+C E + C+AS+P AHPP + D T WQS + ++ Sbjct: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128 Query: 116 PSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAF 175 P +TLS K E+T V + F RP M + KS+D GRTW P+QFY+ C + + Sbjct: 129 PH--NVTLTLSLGKKFEVTY-VSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185 Query: 176 GMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYT 235 R ++ + +CT+ ++ + F D P + DN Sbjct: 186 NRPHRAP--ITKQNEQEAVCTDSHTDMRPLSGGL-IAFSTLD-----GRPSAHDFDN--- 234 Query: 236 RLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRENLY---KYFYAISNIEVIGRCKCNLH 292 + L+++ T TD+R+ R G + ++ YFYA+S+++V GRCKCN H Sbjct: 235 ----SPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGH 290 Query: 293 ANLCSM-REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFG 351 A C R+ SL C+C HNT GP+C +CK R W+ + N C Sbjct: 291 AARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAR-----EANECVA----- 340 Query: 352 NCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404 C C H+ RC + L ++ C++C+HNT G+HC +C+ GYYR+ + Sbjct: 341 -CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRK 399 Query: 405 VCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441 C C+C+ +G+ CN+ TG C C++G G C+ C Sbjct: 400 ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437 Score = 63.2 bits (152), Expect = 6e-10 Identities = 45/156 (28%), Positives = 64/156 (41%), Gaps = 20/156 (12%) Query: 351 GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNG--SAELDDENVCIE 408 G C+C GH+ RC D + + C C+HNT G C C+ +Y A + N C+ Sbjct: 283 GRCKCNGHAARCVR-DRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340 Query: 409 CNCN----------QIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQG---CYPNV 455 CNCN ++ + R + CR AG C C +Y G + Sbjct: 341 CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400 Query: 456 CD--DDQLLCQNGGTCLQNQ-RCACPRGYTGVRCEQ 488 C D + G TC Q +C C G TG+ C + Sbjct: 401 CKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNR 436 Score = 30.4 bits (67), Expect = 4.2 Identities = 17/67 (25%), Positives = 27/67 (40%), Gaps = 8/67 (11%) Query: 287 CK-CNLH-----ANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340 CK C+ H C+ G QC C+ TG C +C K ++ + +P Sbjct: 401 CKACDCHPVGAAGKTCNQTTG--QCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAP 458 Query: 341 PNACATA 347 P A++ Sbjct: 459 PTTAASS 465 >gi|110611156 laminin, gamma 3 precursor [Homo sapiens] Length = 1575 Score = 197 bits (500), Expect = 3e-50 Identities = 142/452 (31%), Positives = 199/452 (44%), Gaps = 58/452 (12%) Query: 60 TCGDPPERFCSHENPYLCS---NECDASNPDLAHPPRLMFDKEEEGLATYWQSITWS--- 113 TCG PPE FC H CDA++P H + D + +T+WQS + + Sbjct: 53 TCGSPPEDFCPHVGAAGAGAHCQRCDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFGV 112 Query: 114 RYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCME 173 +YP+ + NITL K E+T V + F RP + K W+PYQFY+ C + Sbjct: 113 QYPTSV--NITLRLGKAYEITY-VRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQK 169 Query: 174 AFGMSARRARDMSSSSAHRV-LCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDN 232 +G + + RV CT E+S +V F L + Sbjct: 170 TYGRP--EGQYLRPGEDERVAFCTSEFSD-ISPLSGGNVAFST-----------LEGRPS 215 Query: 233 LYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQREN--LYKYFYAISNIEVIGRCKCN 290 Y E + GL+E+ T T+L + L R G + ++ L Y+YA+S+ V GRCKCN Sbjct: 216 AYN-FEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCN 274 Query: 291 LHANLCSMR-EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGS 349 HA+ C G L C C+HNTTG DC +C F+ R W G+ P Sbjct: 275 GHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP-------- 326 Query: 350 FGNCECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404 C C G S C++ L T C C+ +T G HC+ C+ +Y D Sbjct: 327 ---CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYH-----WDPRM 378 Query: 405 VCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY--WRQGCYPNVCDDDQLL 462 C C+C GS+H +C++TG C C+ G KCD CLP + GC P C+ L Sbjct: 379 PCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL 438 Query: 463 CQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493 TC ++ RC C G C+ RC P Sbjct: 439 ----DTCDPRSGRCPCKENVEGNLCD--RCRP 464 Score = 83.2 bits (204), Expect = 5e-16 Identities = 75/315 (23%), Positives = 104/315 (33%), Gaps = 102/315 (32%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSW--RAGSYLPLPHGSPNAC 344 C CN H C G C C H+T GP C +C F + +A P P +AC Sbjct: 707 CTCNQHGT-CDPNTGI--CVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSAC 763 Query: 345 ATA--------------------------------GSFGN------CECYGH--SNRCSY 364 T G FG+ C+C G+ N Sbjct: 764 TTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGN 823 Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSA-------------------------- 398 D L+ C+ C HNT G HC+HC+ G+Y + A Sbjct: 824 CDPLSG-HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDP 882 Query: 399 ------------------------ELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGA 433 +L C C C+ +GS D+C+ +TG C CR G Sbjct: 883 VTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGV 942 Query: 434 AGPKCDDCLPTHYWR--QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRC 491 G CD C + +GC C L C +N C C G+ G +C++ Sbjct: 943 TGQACDRCQLGFFGFSIKGCRACRCSP---LGAASAQCHENGTCVCRPGFEGYKCDRCHD 999 Query: 492 DPADDDGGLDCDRAP 506 + G C + P Sbjct: 1000 NFFLTADGTHCQQCP 1014 Score = 58.5 bits (140), Expect = 1e-08 Identities = 42/128 (32%), Positives = 49/128 (38%), Gaps = 21/128 (16%) Query: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCEC 429 V SC GQ C+ C GY R + C+ C CNQ H C+ TG C C Sbjct: 670 VEICSCPTGYTGQFCESCAPGYKRE-MPQGGPYASCVPCTCNQ----HGTCDPNTGICVC 724 Query: 430 REGAAGPKCDDCLPTHYWR------QGCYPNVCDDDQLLCQNGGTCLQNQR---CA-CPR 479 GP C+ CLP Y C P C Q+ T + R C CP Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPG-----QSACTTIPESREVVCTHCPP 779 Query: 480 GYTGVRCE 487 G G RCE Sbjct: 780 GQRGRRCE 787 Score = 47.0 bits (110), Expect = 4e-05 Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 24/139 (17%) Query: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364 C C TG C C ++ +P G P A C C H C Sbjct: 673 CSCPTGYTGQFCESCAPGYKRE---------MPQGGPYASCVP-----CTCNQHGT-CDP 717 Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC--NQIGSVHDRCN 422 N CV C H+T G C+ C G+Y N A D+ C C C + Sbjct: 718 ----NTGICV-CSHHTEGPSCERCLPGFYGNPFAGQADD--CQPCPCPGQSACTTIPESR 770 Query: 423 ETGFCECREGAAGPKCDDC 441 E C G G +C+ C Sbjct: 771 EVVCTHCPPGQRGRRCEVC 789 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 16/77 (20%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C CN +L + S +C C+ N G C +C R G++ PH +P C++ Sbjct: 430 CTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRC---------RPGTFNLQPH-NPAGCSS 479 Query: 347 AGSFGNCECYGHSNRCS 363 C CYGHS C+ Sbjct: 480 ------CFCYGHSKVCA 490 >gi|5453810 netrin 3 [Homo sapiens] Length = 580 Score = 194 bits (494), Expect = 1e-49 Identities = 123/393 (31%), Positives = 186/393 (47%), Gaps = 50/393 (12%) Query: 60 TCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPL 119 TCG P R CDAS+P AH P L+ W+S + R +PL Sbjct: 58 TCGRPATR------------ACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103 Query: 120 EANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSA 179 +T+ K EL V + F P + L KS D+GR+W P F++ C +G Sbjct: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162 Query: 180 RRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLES 239 A + + ++ GS + F ++D + P L L+S Sbjct: 163 APANGPAGPGPEALCFPAPLAQPDGSGL---LAFSMQDS----SPPGL--------DLDS 207 Query: 240 AKGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSM- 298 + L+++ T TD+R+ L RP+ G E + Y YA ++++V GRCKCN HA+ C + Sbjct: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267 Query: 299 REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGH 358 +G L C+C H T GPDCG+CK + R W+ + +AC C C GH Sbjct: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRAT-----ARESHACLA------CSCNGH 316 Query: 359 SNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 411 + RC + L ++ C++C+HNT G+HC +CR G+YR+ L D C C+C Sbjct: 317 ARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDC 376 Query: 412 NQIGSVHDRCNE-TGFCECREGAAGPKCDDCLP 443 + +G+ CN+ TG C C++G G C+ C P Sbjct: 377 HPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409 Score = 62.8 bits (151), Expect = 8e-10 Identities = 55/185 (29%), Positives = 72/185 (38%), Gaps = 45/185 (24%) Query: 351 GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNG--SAELDDENVCIE 408 G C+C GH++RC +D + C C+H T G C C+ Y A + + C+ Sbjct: 253 GRCKCNGHASRC-LLDTQGHLIC-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLA 310 Query: 409 CNCNQIGSVHDRCN------------ETGFC-ECREGAAGPKCDDCLPTHYWRQGCY--P 453 C+CN RC G C CR AG C HY R+G Y P Sbjct: 311 CSCNGHAR---RCRFNMELYRLSGRRSGGVCLNCRHNTAGRHC------HYCREGFYRDP 361 Query: 454 NVCDDDQLLCQN---------GGTCLQNQ-RCACPRGYTGVRCEQPRCDPADDDGGLDCD 503 D+ C+ G TC Q +C C G TG+ C RC P G Sbjct: 362 GRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCN--RCAP-----GFQQS 414 Query: 504 RAPGA 508 R+P A Sbjct: 415 RSPVA 419 >gi|21264602 laminin alpha 5 [Homo sapiens] Length = 3695 Score = 189 bits (480), Expect = 5e-48 Identities = 158/521 (30%), Positives = 220/521 (42%), Gaps = 120/521 (23%) Query: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140 C A+N + AHP D G +WQS SR E N+TL + + ++ Sbjct: 106 CTAANSNKAHPASNAID----GTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKF 161 Query: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSA--RRARDMSSSSAHRVLC 195 RP + VLE+S+D GRT+QP+QF+A DC+E FG R RD ++ +C Sbjct: 162 ANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFGPQTLERITRDDAA------IC 215 Query: 196 TEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMR 255 T EYSR + + V V R P N Y+ L L+EF T++R+R Sbjct: 216 TTEYSRIVPLENGEIVVSLVNGR------PGAMNFS--YSPL-----LREFTKATNVRLR 262 Query: 256 LLRP------ALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGS----LQC 305 LR +G +Y+Y+I +I + GRC C+ HA+ C ++ + LQC Sbjct: 263 FLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQC 322 Query: 306 ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY- 364 C+HNT G C +C F + W+ P S N C + C CYGH+ C Y Sbjct: 323 TCQHNTCGGTCDRCCPGFNQQPWK-----PATANSANECQS------CNCYGHATDCYYD 371 Query: 365 --ID-----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC 411 +D + C+ C+H+T G +C+ C G+YR+ + LD +VC CNC Sbjct: 372 PEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNC 431 Query: 412 NQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDD----DQLL---- 462 + C + TG C CR +G +CD C CYP +Q+L Sbjct: 432 -ESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQ 490 Query: 463 -----CQNGGT----CLQNQ---RCACPRGYTGVRCE-----------QP---------- 489 C GT C ++ RC C + G CE QP Sbjct: 491 IVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVAD 550 Query: 490 -RCDPADDDG---------GLDCDR-APGAAPRP-ATLLGC 518 RCDP D G G CDR APG P L GC Sbjct: 551 DRCDP--DTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGC 589 Score = 81.6 bits (200), Expect = 2e-15 Identities = 70/265 (26%), Positives = 98/265 (36%), Gaps = 63/265 (23%) Query: 276 YAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLP 335 + + + V RC C + + + +C C N +G C C + F S P Sbjct: 418 HPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFP----SCYP 473 Query: 336 LPHGSPNA---CATAGSFGNCECYG---HSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCR 389 P S + AG NC+C N C V C+ CK N +G HC+ C Sbjct: 474 TPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDP--RVGRCL-CKPNFQGTHCELCA 530 Query: 390 LGYYRNG-------SAELDDEN------------------------------VCIECNCN 412 G+Y G S + D+ +C C C+ Sbjct: 531 PGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCS 590 Query: 413 QIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDD----DQLLCQNGGT 468 G++ + C+E G C C+ AGP CD C P ++ C CD DQ LC GG Sbjct: 591 PAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQ-LCGAGGL 649 Query: 469 CLQNQRCACPRGYTGVRCEQPRCDP 493 C C GYTG C++ C P Sbjct: 650 ------CRCRPGYTGTACQE--CSP 666 Score = 74.3 bits (181), Expect = 3e-13 Identities = 66/229 (28%), Positives = 90/229 (39%), Gaps = 49/229 (21%) Query: 290 NLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGS 349 N A C +R G QC C+ G C +C F PL GS S Sbjct: 1922 NNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGN--------PLVLGS--------S 1965 Query: 350 FGNCECYGHSNRCSYIDFLNVVT--CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 407 C+C G+ + + +T C C +T G C+ C G+Y G+A L C Sbjct: 1966 CQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY--GNALLPGN--CT 2021 Query: 408 ECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYWRQ---GCYPNVC------- 456 C+C G+ + C+ +G C C+ G G +CD C H+ GC P C Sbjct: 2022 RCDCTPCGT--EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGS 2079 Query: 457 ----DDDQLLCQNGGTCLQNQRCACPRGYTGV------RCEQP--RCDP 493 Q C+ G Q + CA GY G+ RC+ P RCDP Sbjct: 2080 ECHPQSGQCHCRPGTMGPQCRECA--PGYWGLPEQGCRRCQCPGGRCDP 2126 Score = 72.0 bits (175), Expect = 1e-12 Identities = 56/221 (25%), Positives = 81/221 (36%), Gaps = 41/221 (18%) Query: 284 IGRCKCN-----LHANLCS---MREGSLQCECEH-----NTTGPDCGKCKKNF----RTR 326 +GRC C H LC+ G C+C + PD G+C+ T Sbjct: 512 VGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATC 571 Query: 327 SWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQ 386 A Y P C+ AG+ E + RC C+ G HC Sbjct: 572 DRCAPGYFHFPLCQLCGCSPAGTLP--EGCDEAGRCL------------CQPEFAGPHCD 617 Query: 387 HCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY 446 CR GY+ + C C C+ G++ C G C CR G G C +C P + Sbjct: 618 RCRPGYHGFPN--------CQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFH 669 Query: 447 WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCE 487 C P C + L + ++ +C+C TG+RC+ Sbjct: 670 GFPSCVPCHCSAEGSL--HAACDPRSGQCSCRPRVTGLRCD 708 Score = 69.7 bits (169), Expect = 6e-12 Identities = 56/196 (28%), Positives = 75/196 (38%), Gaps = 35/196 (17%) Query: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364 C C + G C +C F +R L L P C+C+GHS+RC Sbjct: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVP-----------CQCHGHSDRC-- 1873 Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN---QIGSVHDRC 421 CV C+HNT G HC+ C+ G+ S+ D C+ C C + + C Sbjct: 1874 --LPGSGVCVDCQHNTEGAHCERCQAGFV---SSRDDPSAPCVSCPCPLSVPSNNFAEGC 1928 Query: 422 NETG---FCECREGAAGPKCDDCLPTHYWR-----QGCYPNVC--DDDQLLCQNGGTCLQ 471 G C C+ G AG C+ C P + C P C + D L + L Sbjct: 1929 VLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLT 1988 Query: 472 NQRCACPRGYTGVRCE 487 C R TG RCE Sbjct: 1989 GACRGCLRHTTGPRCE 2004 Score = 62.4 bits (150), Expect = 1e-09 Identities = 43/153 (28%), Positives = 60/153 (39%), Gaps = 24/153 (15%) Query: 297 SMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPN-ACATAGSFGN-CE 354 ++ E + C C + GP C +CK F W G P G +C G+ G E Sbjct: 736 ALPEAQVPCMCRAHVEGPSCDRCKPGF----W--GLSPSNPEGCTRCSCDLRGTLGGVAE 789 Query: 355 CYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQI 414 C + +C CK + GQ C C+ G++ A D C C C+ Sbjct: 790 CQPGTGQC------------FCKPHVCGQACASCKDGFFGLDQA---DYFGCRSCRCDIG 834 Query: 415 GSVHDRCN-ETGFCECREGAAGPKCDDCLPTHY 446 G++ C TG C CR GP C + HY Sbjct: 835 GALGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867 Score = 57.8 bits (138), Expect = 2e-08 Identities = 45/160 (28%), Positives = 57/160 (35%), Gaps = 40/160 (25%) Query: 289 CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAG 348 C+ A LC G QC C T PDC C+ P G C Sbjct: 1484 CDCGARLCDELTG--QCICPPRTIPPDCLLCQ--------------PQTFG----CHPLV 1523 Query: 349 SFGNCECYGHSNRCSYIDFLNVVTC------VSCKHNTRGQHCQHCRLGYYRNGSAELDD 402 C C G I L TC C+ N G+ C C G++ Sbjct: 1524 GCEECNCSGPG-----IQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR----- 1573 Query: 403 ENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441 C C+C++ G+ C+ TG C C+E GPKCD C Sbjct: 1574 ---CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQC 1610 Score = 53.5 bits (127), Expect = 5e-07 Identities = 42/162 (25%), Positives = 56/162 (34%), Gaps = 36/162 (22%) Query: 286 RCKCN-LHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344 RC C C G C C+ TG C +C++ G + G C Sbjct: 2022 RCDCTPCGTEACDPHSG--HCLCKAGVTGRRCDRCQE---------GHFGFDGCGGCRPC 2070 Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404 A + EC+ S +C C+ T G C+ C GY+ E Sbjct: 2071 ACGPAAEGSECHPQSGQCH------------CRPGTMGPQCRECAPGYWGL------PEQ 2112 Query: 405 VCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTH 445 C C C RC+ TG C C G +G +CD C H Sbjct: 2113 GCRRCQCPG-----GRCDPHTGRCNCPPGLSGERCDTCSQQH 2149 Score = 50.8 bits (120), Expect = 3e-06 Identities = 52/195 (26%), Positives = 69/195 (35%), Gaps = 51/195 (26%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363 QC C + G DC +C A Y P+ P C G C + +C Sbjct: 1456 QCPCHAHVIGRDCSRC----------ATGYWGFPNCRPCDC------GARLCDELTGQCI 1499 Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGS---VHDR 420 C+ C+ T G C H +G C ECNC+ G Sbjct: 1500 CPPRTIPPDCLLCQPQTFG--C-HPLVG--------------CEECNCSGPGIQELTDPT 1542 Query: 421 CN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC------LQNQ 473 C+ ++G C+CR G +CD C P + C P CD C GT L Q Sbjct: 1543 CDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRP--CD-----CHEAGTAPGVCDPLTGQ 1595 Query: 474 RCACPRGYTGVRCEQ 488 C C G +C+Q Sbjct: 1596 -CYCKENVQGPKCDQ 1609 Score = 38.9 bits (89), Expect = 0.012 Identities = 32/123 (26%), Positives = 43/123 (34%), Gaps = 29/123 (23%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363 QC+C N TG C C F HG P C+C+ Sbjct: 1549 QCKCRPNVTGRRCDTCSPGF--------------HGYPRCRP-------CDCHEAGTAPG 1587 Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423 D L C CK N +G C C LG + S + + C C C G+ +RC Sbjct: 1588 VCDPLTG-QCY-CKENVQGPKCDQCSLGTF---SLDAANPKGCTRCFC--FGAT-ERCRS 1639 Query: 424 TGF 426 + + Sbjct: 1640 SSY 1642 Score = 38.5 bits (88), Expect = 0.015 Identities = 29/115 (25%), Positives = 36/115 (31%), Gaps = 27/115 (23%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C C A S QC C T GP C +C A Y LP C Sbjct: 2070 CACGPAAEGSECHPQSGQCHCRPGTMGPQCREC----------APGYWGLPEQGCRRCQC 2119 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCK-------------HNTRGQHCQHC 388 G C H+ RC+ L+ C +C H+ + C HC Sbjct: 2120 PGG----RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHC 2170 Score = 35.8 bits (81), Expect = 0.100 Identities = 24/90 (26%), Positives = 33/90 (36%), Gaps = 10/90 (11%) Query: 392 YYRNGSAELD--DENVCIECNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHYWR 448 + RN +A L N C C+++G+ C G C C G C C ++ Sbjct: 1419 FCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGF 1478 Query: 449 QGCYPNVCDDDQLLCQNGGTCLQNQRCACP 478 C P CD LC +C CP Sbjct: 1479 PNCRP--CDCGARLCDE-----LTGQCICP 1501 >gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] Length = 3333 Score = 169 bits (427), Expect = 8e-42 Identities = 125/454 (27%), Positives = 193/454 (42%), Gaps = 78/454 (17%) Query: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140 C++ +P AHP D E +WQS S N+TL + + ++ Sbjct: 105 CNSEDPRKAHPVTNAIDGSER----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF 160 Query: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197 RP + VLE+S+D G T+ P+Q++A DC++ FG A +M+ + VLC Sbjct: 161 ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREA----NMAVTRDDDVLCVT 216 Query: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257 EYSR + + V + R P +N +T L+EF T++R+R L Sbjct: 217 EYSRIVPLENGEVVVSLINGR------PGAKNFTFSHT-------LREFTKATNIRLRFL 263 Query: 258 RP-ALGGTYVQREN-----LYKYFYAISNIEVIGRCKCNLHANLCSMR--EGSLQCECEH 309 R L G + + +Y+Y+I +I + G+C CN HA +C++ E +CEC+H Sbjct: 264 RTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQH 323 Query: 310 NTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYID--- 366 +T G C +C + R WR P A + C C+GH++ C Y Sbjct: 324 HTCGETCDRCCTGYNQRRWR-----------PAAWEQSHECEACNCHGHASNCYYDPDVE 372 Query: 367 -----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 415 + C++C+HNT G +C+ C GYYR +D + CI C+C+ Sbjct: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432 Query: 416 SVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCY--------------PNVCDDDQ 460 + D C + +G C C+ G C+ C +Y C P D Sbjct: 433 A--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490 Query: 461 LLCQNGGT----CLQNQRCACPRGYTGVRCEQPR 490 C G C + RC C G G RC+ R Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCR 524 Score = 79.3 bits (194), Expect = 8e-15 Identities = 64/243 (26%), Positives = 93/243 (38%), Gaps = 71/243 (29%) Query: 287 CKCNLHANLC------SMREGSLQCE-----------CEHNTTGPDCGKCKKNFRTRSWR 329 C C+ HA+ C ++ SL + C+HNT G +C +C K Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAK-------- 407 Query: 330 AGSYLP--LPHGSPNACATAGSFGNCE------CYGHSNRCSYIDFLNVVTCVSCKHNTR 381 G Y P +P +P+ C +C+ C S RC CK N Sbjct: 408 -GYYRPYGVPVDAPDGCIPC----SCDPEHADGCEQGSGRCH------------CKPNFH 450 Query: 382 GQHCQHCRLGYYR-------------NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE 428 G +C+ C +GYY S+E C+CN G + + C+ G C Sbjct: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510 Query: 429 CREGAAGPKCDDCLPTHY---WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVR 485 CR G GP+CD C Y Q C+ + Q+ C + +C C G TG R Sbjct: 511 CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS-----VTGQCECRPGVTGQR 565 Query: 486 CEQ 488 C++ Sbjct: 566 CDR 568 Score = 74.7 bits (182), Expect = 2e-13 Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%) Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412 C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C Sbjct: 1687 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 1737 Query: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469 S C G C C+ G G +C+ C P ++ + C C +C Sbjct: 1738 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 1789 Query: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528 N + TG Q +P D +CD TLL L +G RL Sbjct: 1790 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 1842 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/207 (28%), Positives = 84/207 (40%), Gaps = 25/207 (12%) Query: 287 CKCNL-HANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL-PHGSPNA- 343 C C+ HA+ C +GS +C C+ N G +C KC + + +P+ P +P++ Sbjct: 426 CSCDPEHADGCE--QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLR--IPIFPVSTPSSE 481 Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403 AG C+C D C+ C+ G C CR G+Y Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHG--RCL-CRPGVEGPRCDTCRSGFY--------SF 530 Query: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL 462 +C C C+ +GS C+ TG CECR G G +CD CL Y +P+ C Sbjct: 531 PICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY----DFPH-CQGSSSA 585 Query: 463 CQNGGTCLQN-QRCACPRGYTGVRCEQ 488 C GT N C C G C + Sbjct: 586 CDPAGTINSNLGYCQCKLHVEGPTCSR 612 Score = 69.3 bits (168), Expect = 8e-12 Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%) Query: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345 C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC Sbjct: 1687 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 1735 Query: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402 SF C G RC SCK G C+ C GY+ N Sbjct: 1736 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 1780 Query: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441 C C+CN Q+GS H + E ++ + +CDDC Sbjct: 1781 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822 Score = 66.2 bits (160), Expect = 7e-11 Identities = 59/237 (24%), Positives = 89/237 (37%), Gaps = 44/237 (18%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRT-----RSWRA--GSY-LPL-- 336 C CNL L + + +C C GP C C+ F + W + GSY +P Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550 Query: 337 --------PHGSPNAC--ATAGSFGNCECYGHSNRCSYIDFLNV-VTCVSCKHNTRGQHC 385 P + C +G++ C G S+ C +N + CK + G C Sbjct: 551 VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC 610 Query: 386 QHCRLGYYRNGSAELDDENV--CIECNCNQIGSVHD--RCNE-TGFCECREGAAGPKCDD 440 C+L Y+ LD EN C EC C++ G+V C + G C C+ G CD Sbjct: 611 SRCKLLYWN-----LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT 665 Query: 441 C--------LPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489 C ++ QGC ++ +C + C C G C++P Sbjct: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG-----PSGVCQCREHVVGKVCQRP 717 Score = 58.9 bits (141), Expect = 1e-08 Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 22/133 (16%) Query: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFC-EC 429 V +C G CQ C GYYR+ C+ CNCN G + + +G C C Sbjct: 1651 VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNC 1706 Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT------CLQN---QRCACPRG 480 + AG C+ C ++G Y N C T C+ N RC+C G Sbjct: 1707 QHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 1760 Query: 481 YTGVRCEQPRCDP 493 YTG +CE RC P Sbjct: 1761 YTGTQCE--RCAP 1771 Score = 51.6 bits (122), Expect = 2e-06 Identities = 58/238 (24%), Positives = 81/238 (34%), Gaps = 51/238 (21%) Query: 287 CKCNLHANLCSMREGSLQCECEHN-TTGPDCGK------CKKNFRTRSWR--AGSYLPLP 337 CK + + + +G+L CEC TGP C C+ N R A + P Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307 Query: 338 HGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGS 397 P +C G C + +C C T C+ C S Sbjct: 1308 RCKPCSC------GRRLCEEMTGQCR------------CPPRTVRPQCEVCE-----THS 1344 Query: 398 AELDDENVCIECNCNQIGSVH---DRCN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYP 453 C CNC++ G++ C+ ++G C C+ G +CD C Y C P Sbjct: 1345 FSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVP 1404 Query: 454 NVCDDDQL---LCQNG-GTCLQNQRCACPRGYTGVRCEQPR-----CDPADDDGGLDC 502 C+ D +C G G CL C G C R DPA+ G C Sbjct: 1405 CNCNRDGTEPGVCDPGTGACL------CKENVEGTECNVCREGSFHLDPANLKGCTSC 1456 >gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] Length = 3277 Score = 169 bits (427), Expect = 8e-42 Identities = 125/454 (27%), Positives = 193/454 (42%), Gaps = 78/454 (17%) Query: 81 CDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMT 140 C++ +P AHP D E +WQS S N+TL + + ++ Sbjct: 105 CNSEDPRKAHPVTNAIDGSER----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF 160 Query: 141 FEYGRPTVMVLEKSLDNGRTWQPYQFYAE---DCMEAFGMSARRARDMSSSSAHRVLCTE 197 RP + VLE+S+D G T+ P+Q++A DC++ FG A +M+ + VLC Sbjct: 161 ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREA----NMAVTRDDDVLCVT 216 Query: 198 EYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLL 257 EYSR + + V + R P +N +T L+EF T++R+R L Sbjct: 217 EYSRIVPLENGEVVVSLINGR------PGAKNFTFSHT-------LREFTKATNIRLRFL 263 Query: 258 RP-ALGGTYVQREN-----LYKYFYAISNIEVIGRCKCNLHANLCSMR--EGSLQCECEH 309 R L G + + +Y+Y+I +I + G+C CN HA +C++ E +CEC+H Sbjct: 264 RTNTLLGHLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQH 323 Query: 310 NTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYID--- 366 +T G C +C + R WR P A + C C+GH++ C Y Sbjct: 324 HTCGETCDRCCTGYNQRRWR-----------PAAWEQSHECEACNCHGHASNCYYDPDVE 372 Query: 367 -----------FLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIG 415 + C++C+HNT G +C+ C GYYR +D + CI C+C+ Sbjct: 373 RQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEH 432 Query: 416 SVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCY--------------PNVCDDDQ 460 + D C + +G C C+ G C+ C +Y C P D Sbjct: 433 A--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKG 490 Query: 461 LLCQNGGT----CLQNQRCACPRGYTGVRCEQPR 490 C G C + RC C G G RC+ R Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCR 524 Score = 79.3 bits (194), Expect = 8e-15 Identities = 64/243 (26%), Positives = 93/243 (38%), Gaps = 71/243 (29%) Query: 287 CKCNLHANLC------SMREGSLQCE-----------CEHNTTGPDCGKCKKNFRTRSWR 329 C C+ HA+ C ++ SL + C+HNT G +C +C K Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAK-------- 407 Query: 330 AGSYLP--LPHGSPNACATAGSFGNCE------CYGHSNRCSYIDFLNVVTCVSCKHNTR 381 G Y P +P +P+ C +C+ C S RC CK N Sbjct: 408 -GYYRPYGVPVDAPDGCIPC----SCDPEHADGCEQGSGRCH------------CKPNFH 450 Query: 382 GQHCQHCRLGYYR-------------NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE 428 G +C+ C +GYY S+E C+CN G + + C+ G C Sbjct: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510 Query: 429 CREGAAGPKCDDCLPTHY---WRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVR 485 CR G GP+CD C Y Q C+ + Q+ C + +C C G TG R Sbjct: 511 CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS-----VTGQCECRPGVTGQR 565 Query: 486 CEQ 488 C++ Sbjct: 566 CDR 568 Score = 74.7 bits (182), Expect = 2e-13 Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%) Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412 C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C Sbjct: 1687 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 1737 Query: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469 S C G C C+ G G +C+ C P ++ + C C +C Sbjct: 1738 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 1789 Query: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528 N + TG Q +P D +CD TLL L +G RL Sbjct: 1790 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 1842 Score = 71.2 bits (173), Expect = 2e-12 Identities = 59/207 (28%), Positives = 84/207 (40%), Gaps = 25/207 (12%) Query: 287 CKCNL-HANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL-PHGSPNA- 343 C C+ HA+ C +GS +C C+ N G +C KC + + +P+ P +P++ Sbjct: 426 CSCDPEHADGCE--QGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLR--IPIFPVSTPSSE 481 Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403 AG C+C D C+ C+ G C CR G+Y Sbjct: 482 DPVAGDIKGCDCNLEGVLPEICDAHG--RCL-CRPGVEGPRCDTCRSGFY--------SF 530 Query: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL 462 +C C C+ +GS C+ TG CECR G G +CD CL Y +P+ C Sbjct: 531 PICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY----DFPH-CQGSSSA 585 Query: 463 CQNGGTCLQN-QRCACPRGYTGVRCEQ 488 C GT N C C G C + Sbjct: 586 CDPAGTINSNLGYCQCKLHVEGPTCSR 612 Score = 69.3 bits (168), Expect = 8e-12 Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%) Query: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345 C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC Sbjct: 1687 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 1735 Query: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402 SF C G RC SCK G C+ C GY+ N Sbjct: 1736 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 1780 Query: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441 C C+CN Q+GS H + E ++ + +CDDC Sbjct: 1781 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822 Score = 66.2 bits (160), Expect = 7e-11 Identities = 59/237 (24%), Positives = 89/237 (37%), Gaps = 44/237 (18%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRT-----RSWRA--GSY-LPL-- 336 C CNL L + + +C C GP C C+ F + W + GSY +P Sbjct: 491 CDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSS 550 Query: 337 --------PHGSPNAC--ATAGSFGNCECYGHSNRCSYIDFLNV-VTCVSCKHNTRGQHC 385 P + C +G++ C G S+ C +N + CK + G C Sbjct: 551 VTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTC 610 Query: 386 QHCRLGYYRNGSAELDDENV--CIECNCNQIGSVHD--RCNE-TGFCECREGAAGPKCDD 440 C+L Y+ LD EN C EC C++ G+V C + G C C+ G CD Sbjct: 611 SRCKLLYWN-----LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDT 665 Query: 441 C--------LPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489 C ++ QGC ++ +C + C C G C++P Sbjct: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG-----PSGVCQCREHVVGKVCQRP 717 Score = 58.9 bits (141), Expect = 1e-08 Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 22/133 (16%) Query: 371 VTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFC-EC 429 V +C G CQ C GYYR+ C+ CNCN G + + +G C C Sbjct: 1651 VEICACPPAYAGDSCQGCSPGYYRDHKGLYTGR--CVPCNCN--GHSNQCQDGSGICVNC 1706 Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT------CLQN---QRCACPRG 480 + AG C+ C ++G Y N C T C+ N RC+C G Sbjct: 1707 QHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 1760 Query: 481 YTGVRCEQPRCDP 493 YTG +CE RC P Sbjct: 1761 YTGTQCE--RCAP 1771 Score = 51.6 bits (122), Expect = 2e-06 Identities = 58/238 (24%), Positives = 81/238 (34%), Gaps = 51/238 (21%) Query: 287 CKCNLHANLCSMREGSLQCECEHN-TTGPDCGK------CKKNFRTRSWR--AGSYLPLP 337 CK + + + +G+L CEC TGP C C+ N R A + P Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFP 1307 Query: 338 HGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGS 397 P +C G C + +C C T C+ C S Sbjct: 1308 RCKPCSC------GRRLCEEMTGQCR------------CPPRTVRPQCEVCE-----THS 1344 Query: 398 AELDDENVCIECNCNQIGSVH---DRCN-ETGFCECREGAAGPKCDDCLPTHYWRQGCYP 453 C CNC++ G++ C+ ++G C C+ G +CD C Y C P Sbjct: 1345 FSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVP 1404 Query: 454 NVCDDDQL---LCQNG-GTCLQNQRCACPRGYTGVRCEQPR-----CDPADDDGGLDC 502 C+ D +C G G CL C G C R DPA+ G C Sbjct: 1405 CNCNRDGTEPGVCDPGTGACL------CKENVEGTECNVCREGSFHLDPANLKGCTSC 1456 >gi|143770880 laminin, beta 4 [Homo sapiens] Length = 1761 Score = 167 bits (423), Expect = 2e-41 Identities = 116/392 (29%), Positives = 180/392 (45%), Gaps = 72/392 (18%) Query: 137 VVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAF-GMSARRARDMSSSSAHRVLC 195 +++TF+ RP M++E+S D G W+ ++++A+DC +F +++ +A+ + ++C Sbjct: 129 LILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD-----IVC 183 Query: 196 TEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMR 255 +YS S + V + F I +N Y+ +++ TLT+LR+ Sbjct: 184 DSKYSDIEPSTGGEVVLKVLDPSFEI---------ENPYSPY-----IQDLVTLTNLRIN 229 Query: 256 LLR-PALGGTYV---QRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE---GSL----- 303 + LG + Q ++L KY+YA+ + V G C CN HA+ C + G + Sbjct: 230 FTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPG 289 Query: 304 ----QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHS 359 QC C+HNT GP+C +CK F+ WR + L NAC + C C HS Sbjct: 290 MVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL-----QDNACRS------CSCNSHS 338 Query: 360 NRCSY-------IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412 +RC + L+ C C+HNT GQHC CR +YR+ + D CI C C+ Sbjct: 339 SRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECD 398 Query: 413 QIGSVHDRC----------NETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVCD 457 G++ + G C C+E G KCD C P HY GC P CD Sbjct: 399 PDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQP--CD 456 Query: 458 DDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQ 488 + L TC + +C C TG CE+ Sbjct: 457 CNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE 488 Score = 69.3 bits (168), Expect = 8e-12 Identities = 59/198 (29%), Positives = 80/198 (40%), Gaps = 41/198 (20%) Query: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCK---------KNFRTRSWRAGS 332 C CN + ++ CS G C HNT G +C CK + R S A Sbjct: 970 CACNNNIDVTDPESCSRVTGEC-LRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASG 1028 Query: 333 YLPL--PHGSPNACATAGSFGNCECYGH-----SNRCS--YIDFLNVVTCVSCKHNTR-- 381 P+ P G AC G C C + +RC+ Y + + C SC + R Sbjct: 1029 VSPMECPPGG-GACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTS 1087 Query: 382 -GQHCQH------CRLGYYRNGSAEL------DDENVCIECNCNQIGSVHDRCN-ETGFC 427 HC C+LGY +E D CI C+CN+ G+ C+ +TG C Sbjct: 1088 QSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMC 1147 Query: 428 ECREGAAGPKCDDCLPTH 445 CREG +G +CD C H Sbjct: 1148 RCREGVSGQRCDRCARGH 1165 Score = 56.6 bits (135), Expect = 5e-08 Identities = 38/146 (26%), Positives = 60/146 (41%), Gaps = 24/146 (16%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG-SPNACATAGSFGNCECYGHSNRC 362 QC C+ N G C +CK N G P G P C GS C + +C Sbjct: 422 QCLCKENVEGAKCDQCKPN------HYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQC 475 Query: 363 SYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN 422 + ++ G HC+ C +GY+ G + + C C+C+ G+ + C+ Sbjct: 476 LCLSYVT------------GAHCEECTVGYWGLG----NHLHGCSPCDCDIGGAYSNVCS 519 Query: 423 -ETGFCECREGAAGPKCDDCLPTHYW 447 + G CECR G C + P +++ Sbjct: 520 PKNGQCECRPHVTGRSCSEPAPGYFF 545 Score = 55.8 bits (133), Expect = 9e-08 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 15/127 (11%) Query: 376 CKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAA 434 CK G+ C C G Y G + C C+C+ GS C++ TG C C + Sbjct: 790 CKPLVVGRCCDRCSTGSYDLG------HHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVS 843 Query: 435 GPKCDDCLPTHYWRQGCYP-------NVCDDDQLLCQNGGTCLQNQRC-ACPRGYTGVRC 486 G +CD CL ++ C+P +CD + C N G + C C GY G Sbjct: 844 GRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPS 903 Query: 487 EQPRCDP 493 C P Sbjct: 904 SGQPCRP 910 Score = 50.8 bits (120), Expect = 3e-06 Identities = 73/300 (24%), Positives = 97/300 (32%), Gaps = 93/300 (31%) Query: 287 CKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS-PN 342 CKC+ ++ CS G QC+C+ G C +C GSY HG P Sbjct: 769 CKCHPQGSVGSSCSRLGG--QCQCKPLVVGRCCDRCS---------TGSYDLGHHGCHPC 817 Query: 343 ACATAGS--------FGNCECYGH-----SNRC--SYIDFLN----------------VV 371 C GS G C C+G +RC Y F + Sbjct: 818 HCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETG 877 Query: 372 TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC------NQI---GSVHDRCN 422 +C +C T G++C+ C GYY N S+ C C C NQ + + Sbjct: 878 SCFNCGGFTTGRNCERCIDGYYGNPSS----GQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933 Query: 423 ETGFCECREGAAGPKCDDCLPTHYWR-----QGCYPNVCD------DDQLLCQNGGTCL- 470 C C +G G +C +C Y C P C+ D + + G CL Sbjct: 934 SDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993 Query: 471 -----QNQRC-ACPRGYTGVRCEQP--------------RCDPADDDGGLDCDRAPGAAP 510 Q C C G+ G Q C P G CD GA P Sbjct: 994 CLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPG--GGACLCDPVTGACP 1051 Score = 42.4 bits (98), Expect = 0.001 Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 19/110 (17%) Query: 397 SAELDDENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLPTHY--WRQGCYP 453 SA+L D V C C+ GSV C+ G C+C+ G CD C Y GC+P Sbjct: 759 SAKLHDGAVA--CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHP 816 Query: 454 NVC----DDDQLLCQNGGTC-----LQNQRC-ACPRGYTGVRCEQPRCDP 493 C D + Q G C + +RC C GY G P C P Sbjct: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF----PSCHP 862 >gi|93204871 netrin 4 [Homo sapiens] Length = 628 Score = 162 bits (410), Expect = 7e-40 Identities = 141/464 (30%), Positives = 201/464 (43%), Gaps = 90/464 (19%) Query: 38 ACQPKVMRLKDYVKVKVEPSGITCG-DPPERFCSH-ENPYLCSNE-----CDASNPDLAH 90 AC P++ L K+ + TCG + E +C + EN L + C+A+ P LAH Sbjct: 33 ACNPRMGNLALGRKLWADT---TCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAH 89 Query: 91 PPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMV 150 P M D T+WQS I L T +VM F+ RP MV Sbjct: 90 LPSAMADSSFRFPRTWWQSAE-----DVHREKIQLDLEAEFYFTHLIVM-FKSPRPAAMV 143 Query: 151 LEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKH 210 L++S D G+TW+PY+++A +C FG+ D+ A +CT +YS Sbjct: 144 LDRSQDFGKTWKPYKYFATNCSATFGLED----DVVKKGA---ICTSKYSS--------- 187 Query: 211 VRFEVRDRFAIF-AGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRE 269 F IF A + +N Y SAK ++E +T+LR++LL+ QR Sbjct: 188 -PFPCTGGEVIFKALSPPYDTENPY----SAK-VQEQLKITNLRVQLLKRQ--SCPCQRN 239 Query: 270 NLYKY-----FYAISNIEVIGRCKCNLHANLCSMREGSL-------------QCECEHNT 311 +L + YAI + V G C CN HA+ C G +C C+HNT Sbjct: 240 DLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNT 299 Query: 312 TGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVV 371 G C C + R W A G+PN C T C+C GH++ C + +NV Sbjct: 300 AGSHCQHCAPLYNDRPWEAADGKT---GAPNECRT------CKCNGHADTCHFD--VNVW 348 Query: 372 ---------TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN 422 C C+HNT GQ+CQ C+ G+YR+ + C C+C+ +GS N Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408 Query: 423 ETGFCE-------CREGAAGPKCDDCLPTHYW---RQGCYPNVC 456 FC+ C+ G AG +CD C+ YW GC P C Sbjct: 409 SVTFCDPSNGDCPCKPGVAGRRCDRCM-VGYWGFGDYGCRPCDC 451 >gi|119703755 laminin, beta 2 precursor [Homo sapiens] Length = 1798 Score = 158 bits (400), Expect = 1e-38 Identities = 148/506 (29%), Positives = 213/506 (42%), Gaps = 91/506 (17%) Query: 60 TCG-DPPERFC--SH----ENPYLCSNECDASNPDLAHPPRL---MFDKEEEGLATYWQS 109 TCG + P+ +C SH + +LC + S D H R+ + + A +WQS Sbjct: 67 TCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQS 126 Query: 110 ITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAE 169 + P+ I L T ++MTF+ RP M++E+S D GRTW Y++++ Sbjct: 127 E--NGIPA---VTIQLDLEAEFHFTH-LIMTFKTFRPAAMLVERSADFGRTWHVYRYFSY 180 Query: 170 DCMEAF-GMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLR 228 DC F G+ R V+C YS S E V + V D P Sbjct: 181 DCGADFPGVPLAPPRHWDD-----VVCESRYSEIEPST-EGEVIYRVLDPAIPIPDPYSS 234 Query: 229 NMDNLYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCK 288 + NL L TL D LL P +RE KY+YA+ + V G C Sbjct: 235 RIQNLLKITNLRVNLTRLHTLGD---NLLDP-------RREIREKYYYALYELVVRGNCF 284 Query: 289 CNLHANLCSMREGSLQ---------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG 339 C HA+ C+ G+ C C+HNT G +C +C+ +R WR P G Sbjct: 285 CYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWR-----PAEDG 339 Query: 340 SPNACATAGSFGNCECYGHSNRCS-----YIDFLNVV--TCVSCKHNTRGQHCQHCRLGY 392 +AC CEC+GH++ C Y+ NV C C+HNT G+HC+ CR + Sbjct: 340 HSHACR------KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFF 393 Query: 393 YRNGSAELDDENVCIECNCNQIGSVH-DRCNE---------TGFCECREGAAGPKCDDCL 442 YR+ + +L D VC C+C+ +GS RC+ +G C C+E G +C C Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453 Query: 443 PTHYW-----RQGCYPNVCD-----DDQLLCQ-NGGTC-----LQNQRC-ACPRGYTGVR 485 + R GC C+ C N G+C + + C C G+ G+ Sbjct: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS 513 Query: 486 CEQPRCDPADDD--GGLD--CDRAPG 507 + C P D D G LD CD G Sbjct: 514 HDLLGCRPCDCDVGGALDPQCDEGTG 539 Score = 79.7 bits (195), Expect = 6e-15 Identities = 73/281 (25%), Positives = 102/281 (36%), Gaps = 75/281 (26%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFR--TRSWRAGSYLPLP----HGS 340 C CN HA+ C+ G+ C +T G C +C F R G P P GS Sbjct: 877 CVCNGHADECNTHTGAC-LGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGS 935 Query: 341 PNACATA----------------------------GSFGN----------CECYGHSNRC 362 AT+ G FG+ CEC G+ + Sbjct: 936 QRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPM 995 Query: 363 SYIDFLNVVT--CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 420 D + T C+ C H+T G HC HC+ G++ + + C C CN +G+ + Sbjct: 996 DP-DACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQ-----SCHRCTCNLLGTNPQQ 1049 Query: 421 C---------NETGFCECREGAAGPKCDDCLPTHYWR----QGCYPNVCDDDQLLCQNGG 467 C +G C C GP CD C P ++W GC P C + G Sbjct: 1050 CPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAP-NFWNLTSGHGCQPCACHPSR---ARGP 1105 Query: 468 TCLQ-NQRCACPRGYTGVRCEQPR----CDPADDDGGLDCD 503 TC + +C C G+ G C + + DP DCD Sbjct: 1106 TCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCD 1146 Score = 79.7 bits (195), Expect = 6e-15 Identities = 62/229 (27%), Positives = 84/229 (36%), Gaps = 40/229 (17%) Query: 285 GRCK-CNLHANLCSMREGSL-----QC-ECEHNTTGPDCGKCKKNFRTRSWRAGSY---L 334 GRC+ C N+ M + QC C H+T GP C CK F ++ R + Sbjct: 981 GRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTC 1040 Query: 335 PLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYR 394 L +P C + C C S +C C N +G C C ++ Sbjct: 1041 NLLGTNPQQCPSPDQ---CHCDPSSGQCP------------CLPNVQGPSCDRCAPNFWN 1085 Query: 395 NGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYP 453 L + C C C+ + CNE TG C CR G G C +C H+ G Sbjct: 1086 -----LTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC 1140 Query: 454 NVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQ---------PRCDP 493 + CD D C+C G +GVRC+Q P C P Sbjct: 1141 HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHP 1189 Score = 63.2 bits (152), Expect = 6e-10 Identities = 56/186 (30%), Positives = 68/186 (36%), Gaps = 38/186 (20%) Query: 341 PNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 400 P C GS + EC H +C CK G+ C C GYY G Sbjct: 782 PCQCNPQGSLSS-ECNPHGGQCL------------CKPGVVGRRCDLCAPGYYGFGPTG- 827 Query: 401 DDENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDD 459 C C C+ G++ C +T G C CR GA G +CD C + C P VC+ Sbjct: 828 -----CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGH 882 Query: 460 QLLCQ-NGGTCLQNQRCACPRGYTGVRCEQPRC------DPADDDGG----LDCDRAPGA 508 C + G CL C G CE RC DP GG C PG+ Sbjct: 883 ADECNTHTGACL-----GCRDHTGGEHCE--RCIAGFHGDPRLPYGGQCRPCPCPEGPGS 935 Query: 509 APRPAT 514 AT Sbjct: 936 QRHFAT 941 Score = 55.5 bits (132), Expect = 1e-07 Identities = 40/130 (30%), Positives = 54/130 (41%), Gaps = 26/130 (20%) Query: 404 NVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHY--WRQGCYPNVCDDD- 459 N + C CN GS+ CN G C C+ G G +CD C P +Y GC C + Sbjct: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEG 837 Query: 460 --QLLCQNGGTCLQNQRCACPRGYTGVRCEQ--------PRCDPADDDGGLD-CDRAPGA 508 LC+ + +C C G G+RC++ P C P +G D C+ GA Sbjct: 838 ALSSLCEK-----TSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGA 892 Query: 509 APRPATLLGC 518 LGC Sbjct: 893 C------LGC 896 Score = 50.1 bits (118), Expect = 5e-06 Identities = 37/144 (25%), Positives = 57/144 (39%), Gaps = 21/144 (14%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363 QC C+ + G C +C+ F S L NA T G+ C +S C Sbjct: 437 QCRCKEHVVGTRCQQCRDGFFGLS--ISDRLGCRRCQCNARGTVP--GSTPCDPNSGSCY 492 Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423 CK G+ C C G++ L C C+C+ G++ +C+E Sbjct: 493 ------------CKRLVTGRGCDRCLPGHWGLSHDLLG----CRPCDCDVGGALDPQCDE 536 Query: 424 -TGFCECREGAAGPKCDDCLPTHY 446 TG C CR+ G +C+ P ++ Sbjct: 537 GTGQCHCRQHMVGRRCEQVQPGYF 560 Score = 32.3 bits (72), Expect = 1.1 Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 28/127 (22%) Query: 275 FYAISNIEVIG--RCKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCKKNFRTRS 327 F+ +S + +G RC+CN + C GS C C+ TG C +C Sbjct: 456 FFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRCLPGH---- 509 Query: 328 WRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQH 387 W G L P C G+ + +C + +C C+ + G+ C+ Sbjct: 510 W--GLSHDLLGCRPCDCDVGGAL-DPQCDEGTGQCH------------CRQHMVGRRCEQ 554 Query: 388 CRLGYYR 394 + GY+R Sbjct: 555 VQPGYFR 561 >gi|62868217 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 152 bits (383), Expect = 1e-36 Identities = 122/464 (26%), Positives = 196/464 (42%), Gaps = 72/464 (15%) Query: 60 TCG-DPPERFCSHENPY-LCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPS 117 TCG PE +C+ + + +CD+ P + R+ G +WQS + Sbjct: 46 TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQS---QNDVN 102 Query: 118 PLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGM 177 P+ + L ++ +V+M F+ P M++E+S D G+TW+ YQ+ A DC F Sbjct: 103 PVSLQLDLDRRFQLQ---EVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFP- 158 Query: 178 SARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRL 237 R R S V C R + G N+ +L + + Sbjct: 159 ---RVRQGRPQSWQDVRCQS---------------LPQRPNARLNGGKVQLNLMDLVSGI 200 Query: 238 ESAKGLK--EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANL 295 + + K E +T+LR+ R L + + +YA+S + + G C C+ HA+ Sbjct: 201 PATQSQKIQEVGEITNLRVNFTR--LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADR 258 Query: 296 CSMREGSLQ-----------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344 C+ + G+ C C+HNT GP+C +C + R WR P Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR-----------PAEG 307 Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397 A C+C GHS C + + + C +C+ +T G++C+ C+L Y+RN Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367 Query: 398 AELDDENVCIECNCNQIGSVHDR-CNE-TGFCECREGAAGPKCDDCLP-----THYWRQG 450 + CI C C+ G+V C+ TG C C+E G +CD C P T+ QG Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG 427 Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493 C+ CD + L + C ++ RC C G +C+Q C P Sbjct: 428 CHR--CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ--CAP 467 Score = 47.8 bits (112), Expect = 3e-05 Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 34/164 (20%) Query: 286 RCKCNLHANLCSMR--EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343 RC CN+ + M E S +C C N GP C +C W+ S P A Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGC---EPCA 482 Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVS-----CKHNTRGQHCQHCRLGYYRNGSA 398 C S +C + +C + + C + C T G CR Sbjct: 483 CDPHNSLSP-QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA-------- 533 Query: 399 ELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441 C+C+ G+ C++ +G C CR G GP+CD C Sbjct: 534 ----------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567 >gi|62868215 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 152 bits (383), Expect = 1e-36 Identities = 122/464 (26%), Positives = 196/464 (42%), Gaps = 72/464 (15%) Query: 60 TCG-DPPERFCSHENPY-LCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPS 117 TCG PE +C+ + + +CD+ P + R+ G +WQS + Sbjct: 46 TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQS---QNDVN 102 Query: 118 PLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGM 177 P+ + L ++ +V+M F+ P M++E+S D G+TW+ YQ+ A DC F Sbjct: 103 PVSLQLDLDRRFQLQ---EVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFP- 158 Query: 178 SARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRL 237 R R S V C R + G N+ +L + + Sbjct: 159 ---RVRQGRPQSWQDVRCQS---------------LPQRPNARLNGGKVQLNLMDLVSGI 200 Query: 238 ESAKGLK--EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANL 295 + + K E +T+LR+ R L + + +YA+S + + G C C+ HA+ Sbjct: 201 PATQSQKIQEVGEITNLRVNFTR--LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADR 258 Query: 296 CSMREGSLQ-----------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344 C+ + G+ C C+HNT GP+C +C + R WR P Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR-----------PAEG 307 Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397 A C+C GHS C + + + C +C+ +T G++C+ C+L Y+RN Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367 Query: 398 AELDDENVCIECNCNQIGSVHDR-CNE-TGFCECREGAAGPKCDDCLP-----THYWRQG 450 + CI C C+ G+V C+ TG C C+E G +CD C P T+ QG Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG 427 Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493 C+ CD + L + C ++ RC C G +C+Q C P Sbjct: 428 CHR--CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ--CAP 467 Score = 47.8 bits (112), Expect = 3e-05 Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 34/164 (20%) Query: 286 RCKCNLHANLCSMR--EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343 RC CN+ + M E S +C C N GP C +C W+ S P A Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGC---EPCA 482 Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVS-----CKHNTRGQHCQHCRLGYYRNGSA 398 C S +C + +C + + C + C T G CR Sbjct: 483 CDPHNSLSP-QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA-------- 533 Query: 399 ELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441 C+C+ G+ C++ +G C CR G GP+CD C Sbjct: 534 ----------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567 >gi|189083719 laminin, beta 3 precursor [Homo sapiens] Length = 1172 Score = 152 bits (383), Expect = 1e-36 Identities = 122/464 (26%), Positives = 196/464 (42%), Gaps = 72/464 (15%) Query: 60 TCG-DPPERFCSHENPY-LCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPS 117 TCG PE +C+ + + +CD+ P + R+ G +WQS + Sbjct: 46 TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQS---QNDVN 102 Query: 118 PLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGM 177 P+ + L ++ +V+M F+ P M++E+S D G+TW+ YQ+ A DC F Sbjct: 103 PVSLQLDLDRRFQLQ---EVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFP- 158 Query: 178 SARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRL 237 R R S V C R + G N+ +L + + Sbjct: 159 ---RVRQGRPQSWQDVRCQS---------------LPQRPNARLNGGKVQLNLMDLVSGI 200 Query: 238 ESAKGLK--EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANL 295 + + K E +T+LR+ R L + + +YA+S + + G C C+ HA+ Sbjct: 201 PATQSQKIQEVGEITNLRVNFTR--LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADR 258 Query: 296 CSMREGSLQ-----------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344 C+ + G+ C C+HNT GP+C +C + R WR P Sbjct: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR-----------PAEG 307 Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397 A C+C GHS C + + + C +C+ +T G++C+ C+L Y+RN Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367 Query: 398 AELDDENVCIECNCNQIGSVHDR-CNE-TGFCECREGAAGPKCDDCLP-----THYWRQG 450 + CI C C+ G+V C+ TG C C+E G +CD C P T+ QG Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG 427 Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493 C+ CD + L + C ++ RC C G +C+Q C P Sbjct: 428 CHR--CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ--CAP 467 Score = 47.8 bits (112), Expect = 3e-05 Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 34/164 (20%) Query: 286 RCKCNLHANLCSMR--EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343 RC CN+ + M E S +C C N GP C +C W+ S P A Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGC---EPCA 482 Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVS-----CKHNTRGQHCQHCRLGYYRNGSA 398 C S +C + +C + + C + C T G CR Sbjct: 483 CDPHNSLSP-QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA-------- 533 Query: 399 ELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441 C+C+ G+ C++ +G C CR G GP+CD C Sbjct: 534 ----------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567 >gi|38788416 laminin, alpha 1 precursor [Homo sapiens] Length = 3075 Score = 147 bits (370), Expect = 3e-35 Identities = 131/487 (26%), Positives = 197/487 (40%), Gaps = 84/487 (17%) Query: 60 TCGDP-PERFCSH---------ENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQS 109 TCG+ PE FC NP + +++NP HP D G +WQS Sbjct: 40 TCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAID----GTNNWWQS 95 Query: 110 ITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYA- 168 + ITL + ++ ++ RP +LE+SLD G T+ P+Q+YA Sbjct: 96 PSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAV 154 Query: 169 --EDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKK-EKHVRFEVRDRFAIFAGP 225 +C+ + ++ RR + + V+CT YSR + E H A P Sbjct: 155 SDSECLSRYNITPRRG-PPTYRADDEVICTSYYSRLVPLEHGEIHTSLINGRPSADDLSP 213 Query: 226 DLRNMDN---LYTRLESAKGLK-EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNI 281 L + + RL+ + L + TL+ + L P + +Y+Y+I +I Sbjct: 214 KLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIV---------TRRYYYSIKDI 264 Query: 282 EVIGRCKCNLHANLCSMREGS--LQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG 339 V G C C HA+ C E + LQC+CEHNT G C +C + + WR G+ Sbjct: 265 SVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTV-----S 319 Query: 340 SPNACATAGSFGNCECYGHSNRCSYID--------------FLNVVTCVSCKHNTRGQHC 385 S N C C C+ + C Y + F C++C NT G +C Sbjct: 320 SGNTCEA------CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINC 373 Query: 386 QHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRC------------NETGFCECREGA 433 + C GYYR ++ C CNC+ +GS+ C + G C C+EG Sbjct: 374 ETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY 433 Query: 434 AGPKCDDC------LPTHYWRQGCYPNVCDDDQLLCQNGGTCLQN---QRC-ACPRGYTG 483 G KCD C PT GC P D+ C C +N + C C G+ Sbjct: 434 TGEKCDRCQLGYKDYPTCV-SCGCNPVGSASDE-PCTGPCVCKENVEGKACDRCKPGFYN 491 Query: 484 VRCEQPR 490 ++ + PR Sbjct: 492 LKEKNPR 498 Score = 90.1 bits (222), Expect = 4e-18 Identities = 70/239 (29%), Positives = 92/239 (38%), Gaps = 25/239 (10%) Query: 286 RCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCK----KNFRTRSWRAGSYLP-LPHGS 340 RC + N E + C+C N + G C + + G++ G Sbjct: 830 RCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGF 889 Query: 341 PNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAEL 400 TA + CEC+ + S + L C CK N GQ C C GYY L Sbjct: 890 YGDAVTAKNCRACECHVKGSH-SAVCHLETGLC-DCKPNVTGQQCDQCLHGYYG-----L 942 Query: 401 DDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQ--GCYPNVCDD 458 D + C CNC+ GSV D C + G C C G AG +CD C Y Q C P C Sbjct: 943 DSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPH 1002 Query: 459 DQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLG 517 Q C + C CP GV+CE+ C +DG D G +L+G Sbjct: 1003 TQNTCDP-----ETGECVCPPHTQGVKCEE--C----EDGHWGYDAEVGCQACNCSLVG 1050 Score = 83.2 bits (204), Expect = 5e-16 Identities = 57/179 (31%), Positives = 73/179 (40%), Gaps = 28/179 (15%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL---PHGSPNA 343 C CN H++ C G C NT G C C + + + S L PH P Sbjct: 1403 CSCNNHSDTCDPNTGKC-LNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPP-- 1459 Query: 344 CATAGSFGNCECYG-HSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402 A C G H RC +C G+HC+ C YY N Sbjct: 1460 ---ASFSPTCVLEGDHDFRCD-----------ACLLGYEGKHCERCSSSYYGNPQTP--- 1502 Query: 403 ENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLPTHYWRQ-GCYPNVCDDD 459 C +C+CN GSVH C+ T G C CR GA+G +CD+C P H + C CDD+ Sbjct: 1503 GGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDCVS--CDDE 1559 Score = 76.6 bits (187), Expect = 5e-14 Identities = 57/227 (25%), Positives = 87/227 (38%), Gaps = 43/227 (18%) Query: 275 FYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYL 334 +Y + + C C++ ++ QC C G C +C F +++ GS Sbjct: 939 YYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGF--YAYQDGSCT 996 Query: 335 PLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYR 394 P C+C N C CV C +T+G C+ C G++ Sbjct: 997 P-----------------CDCPHTQNTCD----PETGECV-CPPHTQGVKCEECEDGHW- 1033 Query: 395 NGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCD----------DCLP 443 D E C CNC+ +GS H RC+ TG C+C+ G CD DC+P Sbjct: 1034 ----GYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVP 1089 Query: 444 THYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPR 490 +G + C+ +Q LC G + C C G +C + R Sbjct: 1090 CDCDLRGTSGDACNLEQGLC---GCVEETGACPCKENVFGPQCNECR 1133 Score = 62.4 bits (150), Expect = 1e-09 Identities = 51/203 (25%), Positives = 71/203 (34%), Gaps = 46/203 (22%) Query: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364 CEC TG C C + +R L G CEC+GH+ C+ Sbjct: 709 CECPQGYTGTSCESCLSGY----YRVDGIL-----------FGGICQPCECHGHAAECNV 753 Query: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC-------NQIGSV 417 C++C HNT G HC+ C G+Y G C C C N + Sbjct: 754 HG-----VCIACAHNTTGVHCEQCLPGFY--GEPSRGTPGDCQPCACPLTIASNNFSPTC 806 Query: 418 HDRCNETGFCE-CREGAAGPKCDDCLPTHYWR-----QGCYPNVCDDDQLLCQNG----- 466 H + C+ C G +G C+ C +Y + C P C + + G Sbjct: 807 HLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSV 866 Query: 467 -GTCLQNQRCACPRGYTGVRCEQ 488 G CL+ C G CE+ Sbjct: 867 TGECLK-----CLGNTDGAHCER 884 Score = 62.0 bits (149), Expect = 1e-09 Identities = 47/161 (29%), Positives = 60/161 (37%), Gaps = 15/161 (9%) Query: 299 REGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGH 358 R G + C NT G +C C + R + Y P P C GS + C Sbjct: 356 RGGGVCINCLQNTMGINCETCIDGYY-RPHKVSPYEDEPC-RPCNCDPVGSLSSV-CIKD 412 Query: 359 SNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVH 418 + C CK G+ C C+LGY D C+ C CN +GS Sbjct: 413 DLHSDLHNGKQPGQC-PCKEGYTGEKCDRCQLGY--------KDYPTCVSCGCNPVGSAS 463 Query: 419 DR-CNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDD 458 D C TG C C+E G CD C P Y + P C + Sbjct: 464 DEPC--TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSE 502 Score = 39.7 bits (91), Expect = 0.007 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 16/78 (20%) Query: 289 CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAG 348 CNL LC E + C C+ N GP C +C R G++ L +P C+ Sbjct: 1102 CNLEQGLCGCVEETGACPCKENVFGPQCNEC---------REGTF-ALRADNPLGCSP-- 1149 Query: 349 SFGNCECYGHSNRCSYID 366 C C G S+ CS ++ Sbjct: 1150 ----CFCSGLSHLCSELE 1163 Score = 29.3 bits (64), Expect = 9.3 Identities = 9/15 (60%), Positives = 11/15 (73%) Query: 473 QRCACPRGYTGVRCE 487 + C CP+GYTG CE Sbjct: 707 EHCECPQGYTGTSCE 721 >gi|167614504 laminin, beta 1 precursor [Homo sapiens] Length = 1786 Score = 142 bits (359), Expect = 6e-34 Identities = 132/502 (26%), Positives = 206/502 (41%), Gaps = 91/502 (18%) Query: 60 TCG-DPPERFC--SH----ENPYLCSNEC---DASNPDLAHPPRLMFDKEEEGLATYWQS 109 TCG PE +C SH + ++C+++ + NPD ++ L +WQS Sbjct: 55 TCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQS 114 Query: 110 ITWSRYPSPLEANITLSWNKTVELT-DDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYA 168 N+T+ + E ++MTF+ RP M++E+S D G+TW Y+++A Sbjct: 115 ENGVE-------NVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFA 167 Query: 169 EDCMEAF-GMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDL 227 DC +F G+S + + ++C YS S E V F D P Sbjct: 168 YDCEASFPGISTGPMKKVDD-----IICDSRYSDIEPST-EGEVIFRALD-------PAF 214 Query: 228 RNMDNLYTRLESAKGLKEFFTLTDLRMRLLR-PALGGTYV--QRENLYKYFYAISNIEVI 284 + D R+++ +T+LR++ ++ LG + + E KY+YA+ ++ V Sbjct: 215 KIEDPYSPRIQN------LLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVR 268 Query: 285 GRCKCNLHANLCSMREGSLQ---------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLP 335 G C C HA+ C+ +G + C C HNT G +C C + WR P Sbjct: 269 GNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWR-----P 323 Query: 336 LPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHC 388 + NAC C C HS C + + + T C C+HNT G++C+ C Sbjct: 324 AEGRNSNACK------KCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQC 377 Query: 389 RLGYYRNGSAELDDENVCIECNCNQIGSVHDR-CNE---------TGFCECREGAAGPKC 438 + YY++ ++ D N C C C+ GS ++ C+ G C C+ G C Sbjct: 378 KPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHC 437 Query: 439 DDCLPTHYWRQ-----GCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDP 493 D C Y GC C+ + + C C R TG C+Q C P Sbjct: 438 DVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ--CLP 495 Query: 494 A------DDDGGLDCDRAPGAA 509 D DG CD G A Sbjct: 496 EHWGLSNDLDGCRPCDCDLGGA 517 Score = 79.3 bits (194), Expect = 8e-15 Identities = 62/220 (28%), Positives = 90/220 (40%), Gaps = 45/220 (20%) Query: 303 LQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRC 362 L C C+ G C C + G+P+ GS C+C+ + + Sbjct: 942 LACVCDPGYIGSRCDDCASGY--------------FGNPSE--VGGSCQPCQCHNNIDTT 985 Query: 363 SYIDFLNVVT--CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDR 420 + + T C+ C ++T G+HCQ CR GYY G A D C +C CN +G+V + Sbjct: 986 DP-EACDKETGRCLKCLYHTEGEHCQFCRFGYY--GDALQQD---CRKCVCNYLGTVQEH 1039 Query: 421 CN--------ETGFCECREGAAGPKCDDCLPTHYWR----QGCYPNVCDDDQLLCQNGGT 468 CN TG C C G CD C P + W+ GC P C+ G + Sbjct: 1040 CNGSDCQCDKATGQCLCLPNVIGQNCDRCAP-NTWQLASGTGCDPCNCNAAHSF---GPS 1095 Query: 469 CLQ-NQRCACPRGYTGVRCEQPR----CDPADDDGGLDCD 503 C + +C C G+ G C + + DP + DCD Sbjct: 1096 CNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCD 1135 Score = 60.5 bits (145), Expect = 4e-09 Identities = 50/162 (30%), Positives = 62/162 (38%), Gaps = 24/162 (14%) Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412 CEC + S D N C C+ N G+ C C G + G + C C C+ Sbjct: 773 CECDPQGSLSSVCD-PNGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG------CKPCECH 824 Query: 413 QIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQN-GGTCL 470 GSV+ CN TG C C +G +CD CLP H+ C P C+ C G CL Sbjct: 825 LQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECL 884 Query: 471 QNQ------RC-ACPRGY-------TGVRCEQPRCDPADDDG 498 Q C C GY +G C C D G Sbjct: 885 NCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSG 926 Score = 58.5 bits (140), Expect = 1e-08 Identities = 45/165 (27%), Positives = 65/165 (39%), Gaps = 35/165 (21%) Query: 286 RCKCNL------HANL--CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP 337 +C CN H N C + + QC C N G +C +C N +W+ S Sbjct: 1027 KCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPN----TWQLASGTGC- 1081 Query: 338 HGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGS 397 P C A SFG C + +C C G+ C C+ ++ + Sbjct: 1082 --DPCNCNAAHSFGP-SCNEFTGQCQ------------CMPGFGGRTCSECQELFWGDPD 1126 Query: 398 AELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441 E C C+C+ G +C++ TG C C EG GP+CD C Sbjct: 1127 VE------CRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKC 1165 Score = 56.6 bits (135), Expect = 5e-08 Identities = 59/259 (22%), Positives = 88/259 (33%), Gaps = 65/259 (25%) Query: 287 CKCNLHANLCSMRE-GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP---HGSPN 342 C+C+ +L S+ + QC+C N G C +C T + P GS N Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPG--TFGFGPSGCKPCECHLQGSVN 830 Query: 343 ACAT---------------------AGSFG-----NCECYGHSNRCSYIDFLNVVTCVSC 376 A G +G C+C GH++ C + C++C Sbjct: 831 AFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPV----TGECLNC 886 Query: 377 KHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ---------IGSVHDRCNETGFC 427 + T G +C+ C GYY G + + C C C D C Sbjct: 887 QDYTMGHNCERCLAGYY--GDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944 Query: 428 ECREGAAGPKCDDCLPTHYWRQG----------CYPNVCDDDQLLC-QNGGTCL------ 470 C G G +CDDC ++ C+ N+ D C + G CL Sbjct: 945 VCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004 Query: 471 QNQRCA-CPRGYTGVRCEQ 488 + + C C GY G +Q Sbjct: 1005 EGEHCQFCRFGYYGDALQQ 1023 >gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo sapiens] Length = 3118 Score = 134 bits (338), Expect = 2e-31 Identities = 127/491 (25%), Positives = 194/491 (39%), Gaps = 78/491 (15%) Query: 60 TCGDP-PERFCSH---------ENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQS 109 TCG+ PE +C NP ++SNP+ HP D G T+WQS Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAID----GKNTWWQS 112 Query: 110 ITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYA- 168 + ITL + ++ +V RP +LE+SLD+ ++P+Q++A Sbjct: 113 PSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVE-YKPWQYHAV 171 Query: 169 --EDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKK-EKHVRFEVRDRFAIFAGP 225 +C+ + + R S + V+CT YS+ + E H+ A P Sbjct: 172 TDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSP 230 Query: 226 DLRNMDNL-YTRLESAKGLKEFFTLT-DLRMRLLR-PALGGTYVQRENLYKYFYAISNIE 282 +L + Y RL + TL DL M + P V R +Y+Y++ +I Sbjct: 231 ELLEFTSARYIRLR----FQRIRTLNADLMMFAHKDPREIDPIVTR----RYYYSVKDIS 282 Query: 283 VIGRCKCNLHANLCSMREGS--LQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340 V G C C HA C + + +CECEHNT G C +C F + WRAG++L Sbjct: 283 VGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFL------ 336 Query: 341 PNACATAGSFGNCECYGHSNRCSYID--------------FLNVVTCVSCKHNTRGQHCQ 386 T C C+G + C Y + ++ C++C NT G +C+ Sbjct: 337 -----TKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE 391 Query: 387 HCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE----------TGFCECREGAAGP 436 C G++R + C C+C+ IGS+++ C + G C C+ G G Sbjct: 392 TCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGV 451 Query: 437 KCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPA-- 494 CD C + C C+ L +N C C C G C RC Sbjct: 452 SCDRCARGYTGYPDC--KACNCSGLGSKNEDPCF--GPCICKENVEGGDCS--RCKSGFF 505 Query: 495 --DDDGGLDCD 503 +D CD Sbjct: 506 NLQEDNWKGCD 516 Score = 88.6 bits (218), Expect = 1e-17 Identities = 60/177 (33%), Positives = 79/177 (44%), Gaps = 23/177 (12%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C+CN H++LC E S+ C+H+T G C +C A Y + G PN C Sbjct: 1420 CQCNGHSSLCDP-ETSICQNCQHHTAGDFCERC----------ALGYYGIVKGLPNDCQQ 1468 Query: 347 AGSFGNCECYGHSNRCS---YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403 C SN S + L+ C +C GQ+C+ C GY GS + Sbjct: 1469 CA----CPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGY--TGSPG-NPG 1521 Query: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDD 459 C EC C+ GS+ C+ TGFC CR GA G KCD C H R+G C D+ Sbjct: 1522 GSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHA-REGWECVFCGDE 1577 Score = 84.0 bits (206), Expect = 3e-16 Identities = 60/213 (28%), Positives = 83/213 (38%), Gaps = 37/213 (17%) Query: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSP 341 C+CN + + C GS C+ TTG C C + G + + P Sbjct: 865 CQCNDNLDFSIPGSCDSLSGSCLI-CKPGTTGRYCELCADGY------FGDAVDAKNCQP 917 Query: 342 NACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELD 401 C GSF C+ + +C C+ N +GQ C C+ G + SA Sbjct: 918 CRCNAGGSFSEV-CHSQTGQCE------------CRANVQGQRCDKCKAGTFGLQSAR-- 962 Query: 402 DENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQL 461 C+ CNCN GS C E+G C C+ G G KCD C ++ Q C+ L Sbjct: 963 ---GCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHL 1019 Query: 462 LCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493 G C + RC CP G +C +C P Sbjct: 1020 ----GNNCDPKTGRCICPPNTIGEKCS--KCAP 1046 Score = 61.6 bits (148), Expect = 2e-09 Identities = 57/243 (23%), Positives = 86/243 (35%), Gaps = 56/243 (23%) Query: 290 NLHANLCSMREGSLQ-----CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344 NL + + +GS+ C+C TG C C W H N Sbjct: 704 NLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESC--------WPR-------HRRVNGT 748 Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404 G C+C+GH+ C + C++CK +T G +C C G+Y G Sbjct: 749 IFGGICEPCQCFGHAESCDDV----TGECLNCKDHTGGPYCDKCLPGFY--GEPTKGTSE 802 Query: 405 VCIECNC-------NQIGSVHDRCNETGFCE-CREGAAGPKCDDCLPTHYWRQ-----GC 451 C C C N + H + C+ C G GP+C+ C ++ + C Sbjct: 803 DCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSC 862 Query: 452 YPNVCDDDQ---------------LLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADD 496 P C+D+ L+C+ G T + CA GY G + C P Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCA--DGYFGDAVDAKNCQPCRC 920 Query: 497 DGG 499 + G Sbjct: 921 NAG 923 Score = 53.5 bits (127), Expect = 5e-07 Identities = 44/136 (32%), Positives = 54/136 (39%), Gaps = 24/136 (17%) Query: 376 CKHNTRGQHCQHCRLGYYR-----NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE-C 429 C G C+ C G+YR G C+ C CN S+ D ET C+ C Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP--ETSICQNC 1439 Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLC-------QNGGTC----LQNQRC-AC 477 + AG C+ C +Y PN C Q C +C L + RC AC Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQ--QCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497 Query: 478 PRGYTGVRCEQPRCDP 493 PRGY G CE RC P Sbjct: 1498 PRGYEGQYCE--RCAP 1511 Score = 51.6 bits (122), Expect = 2e-06 Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 26/186 (13%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C+C+ N C + G +C C NT G C KC N S G C+T Sbjct: 1014 CECSHLGNNCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTGC-------KACNCST 1064 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKH-NTRGQHCQHCRLGYYRNGSAELDDENV 405 GS + +C ++ +C+ + C C + C C + D E Sbjct: 1065 VGSL-DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETK 1123 Query: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQN 465 +C+C+ ++TG C C+ G CD C P + P C C Sbjct: 1124 --KCSCS---------DQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSS----CYC 1168 Query: 466 GGTCLQ 471 GT Q Sbjct: 1169 FGTTTQ 1174 Score = 33.5 bits (75), Expect = 0.49 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 16/75 (21%) Query: 289 CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAG 348 C+ CS + + QC C+ N G C +C R G + L +P C+ Sbjct: 1118 CDSETKKCSCSDQTGQCTCKVNVEGIHCDRC---------RPGKF-GLDAKNPLGCS--- 1164 Query: 349 SFGNCECYGHSNRCS 363 +C C+G + +CS Sbjct: 1165 ---SCYCFGTTTQCS 1176 Score = 32.0 bits (71), Expect = 1.4 Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 27/92 (29%) Query: 427 CECREGAAGPKCDDCLPTHYWRQG-------------CYP-------NVCDDDQLLCQNG 466 C+C G +G C+ CLP Y + C P ++CD + +CQN Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439 Query: 467 GTCLQNQRC-ACPRGYTGV------RCEQPRC 491 C C GY G+ C+Q C Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQQCAC 1471 >gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sapiens] Length = 3122 Score = 134 bits (338), Expect = 2e-31 Identities = 127/491 (25%), Positives = 194/491 (39%), Gaps = 78/491 (15%) Query: 60 TCGDP-PERFCSH---------ENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQS 109 TCG+ PE +C NP ++SNP+ HP D G T+WQS Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNSSNPNQRHPITNAID----GKNTWWQS 112 Query: 110 ITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYA- 168 + ITL + ++ +V RP +LE+SLD+ ++P+Q++A Sbjct: 113 PSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDVE-YKPWQYHAV 171 Query: 169 --EDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKK-EKHVRFEVRDRFAIFAGP 225 +C+ + + R S + V+CT YS+ + E H+ A P Sbjct: 172 TDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLINGRPSADDPSP 230 Query: 226 DLRNMDNL-YTRLESAKGLKEFFTLT-DLRMRLLR-PALGGTYVQRENLYKYFYAISNIE 282 +L + Y RL + TL DL M + P V R +Y+Y++ +I Sbjct: 231 ELLEFTSARYIRLR----FQRIRTLNADLMMFAHKDPREIDPIVTR----RYYYSVKDIS 282 Query: 283 VIGRCKCNLHANLCSMREGS--LQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340 V G C C HA C + + +CECEHNT G C +C F + WRAG++L Sbjct: 283 VGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFL------ 336 Query: 341 PNACATAGSFGNCECYGHSNRCSYID--------------FLNVVTCVSCKHNTRGQHCQ 386 T C C+G + C Y + ++ C++C NT G +C+ Sbjct: 337 -----TKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE 391 Query: 387 HCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE----------TGFCECREGAAGP 436 C G++R + C C+C+ IGS+++ C + G C C+ G G Sbjct: 392 TCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGV 451 Query: 437 KCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPA-- 494 CD C + C C+ L +N C C C G C RC Sbjct: 452 SCDRCARGYTGYPDC--KACNCSGLGSKNEDPCF--GPCICKENVEGGDCS--RCKSGFF 505 Query: 495 --DDDGGLDCD 503 +D CD Sbjct: 506 NLQEDNWKGCD 516 Score = 88.6 bits (218), Expect = 1e-17 Identities = 60/177 (33%), Positives = 79/177 (44%), Gaps = 23/177 (12%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C+CN H++LC E S+ C+H+T G C +C A Y + G PN C Sbjct: 1420 CQCNGHSSLCDP-ETSICQNCQHHTAGDFCERC----------ALGYYGIVKGLPNDCQQ 1468 Query: 347 AGSFGNCECYGHSNRCS---YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403 C SN S + L+ C +C GQ+C+ C GY GS + Sbjct: 1469 CA----CPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGY--TGSPG-NPG 1521 Query: 404 NVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDD 459 C EC C+ GS+ C+ TGFC CR GA G KCD C H R+G C D+ Sbjct: 1522 GSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCKHWHA-REGWECVFCGDE 1577 Score = 84.0 bits (206), Expect = 3e-16 Identities = 60/213 (28%), Positives = 83/213 (38%), Gaps = 37/213 (17%) Query: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSP 341 C+CN + + C GS C+ TTG C C + G + + P Sbjct: 865 CQCNDNLDFSIPGSCDSLSGSCLI-CKPGTTGRYCELCADGY------FGDAVDAKNCQP 917 Query: 342 NACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELD 401 C GSF C+ + +C C+ N +GQ C C+ G + SA Sbjct: 918 CRCNAGGSFSEV-CHSQTGQCE------------CRANVQGQRCDKCKAGTFGLQSAR-- 962 Query: 402 DENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQL 461 C+ CNCN GS C E+G C C+ G G KCD C ++ Q C+ L Sbjct: 963 ---GCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHL 1019 Query: 462 LCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493 G C + RC CP G +C +C P Sbjct: 1020 ----GNNCDPKTGRCICPPNTIGEKCS--KCAP 1046 Score = 61.6 bits (148), Expect = 2e-09 Identities = 57/243 (23%), Positives = 86/243 (35%), Gaps = 56/243 (23%) Query: 290 NLHANLCSMREGSLQ-----CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344 NL + + +GS+ C+C TG C C W H N Sbjct: 704 NLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESC--------WPR-------HRRVNGT 748 Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDEN 404 G C+C+GH+ C + C++CK +T G +C C G+Y G Sbjct: 749 IFGGICEPCQCFGHAESCDDV----TGECLNCKDHTGGPYCDKCLPGFY--GEPTKGTSE 802 Query: 405 VCIECNC-------NQIGSVHDRCNETGFCE-CREGAAGPKCDDCLPTHYWRQ-----GC 451 C C C N + H + C+ C G GP+C+ C ++ + C Sbjct: 803 DCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSC 862 Query: 452 YPNVCDDDQ---------------LLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADD 496 P C+D+ L+C+ G T + CA GY G + C P Sbjct: 863 QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCA--DGYFGDAVDAKNCQPCRC 920 Query: 497 DGG 499 + G Sbjct: 921 NAG 923 Score = 53.5 bits (127), Expect = 5e-07 Identities = 44/136 (32%), Positives = 54/136 (39%), Gaps = 24/136 (17%) Query: 376 CKHNTRGQHCQHCRLGYYR-----NGSAELDDENVCIECNCNQIGSVHDRCNETGFCE-C 429 C G C+ C G+YR G C+ C CN S+ D ET C+ C Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP--ETSICQNC 1439 Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLC-------QNGGTC----LQNQRC-AC 477 + AG C+ C +Y PN C Q C +C L + RC AC Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQ--QCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497 Query: 478 PRGYTGVRCEQPRCDP 493 PRGY G CE RC P Sbjct: 1498 PRGYEGQYCE--RCAP 1511 Score = 51.6 bits (122), Expect = 2e-06 Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 26/186 (13%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C+C+ N C + G +C C NT G C KC N S G C+T Sbjct: 1014 CECSHLGNNCDPKTG--RCICPPNTIGEKCSKCAPNTWGHSITTGC-------KACNCST 1064 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKH-NTRGQHCQHCRLGYYRNGSAELDDENV 405 GS + +C ++ +C+ + C C + C C + D E Sbjct: 1065 VGSL-DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETK 1123 Query: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQN 465 +C+C+ ++TG C C+ G CD C P + P C C Sbjct: 1124 --KCSCS---------DQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSS----CYC 1168 Query: 466 GGTCLQ 471 GT Q Sbjct: 1169 FGTTTQ 1174 Score = 33.5 bits (75), Expect = 0.49 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 16/75 (21%) Query: 289 CNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAG 348 C+ CS + + QC C+ N G C +C R G + L +P C+ Sbjct: 1118 CDSETKKCSCSDQTGQCTCKVNVEGIHCDRC---------RPGKF-GLDAKNPLGCS--- 1164 Query: 349 SFGNCECYGHSNRCS 363 +C C+G + +CS Sbjct: 1165 ---SCYCFGTTTQCS 1176 Score = 32.0 bits (71), Expect = 1.4 Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 27/92 (29%) Query: 427 CECREGAAGPKCDDCLPTHYWRQG-------------CYP-------NVCDDDQLLCQNG 466 C+C G +G C+ CLP Y + C P ++CD + +CQN Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439 Query: 467 GTCLQNQRC-ACPRGYTGV------RCEQPRC 491 C C GY G+ C+Q C Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQQCAC 1471 >gi|219842266 usherin isoform B [Homo sapiens] Length = 5202 Score = 126 bits (317), Expect = 4e-29 Identities = 110/454 (24%), Positives = 193/454 (42%), Gaps = 74/454 (16%) Query: 66 ERFC-SHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANIT 124 +R+C ++ N NP+ AHP + D + + T W S ++ + L +T Sbjct: 316 QRYCIPNDAGDTADNRVSRLNPE-AHPLSFVNDND---VGTSWVSNVFTNI-TQLNQGVT 370 Query: 125 LSWNKTVELTDD------VVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMS 178 +S V+L + +++ F +PT + +++ +N W+ +Q++A +C AFGM Sbjct: 371 IS----VDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM- 424 Query: 179 ARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLE 238 + D+ + L ++ ++ +V F + + GP+ R Y Sbjct: 425 -KNNGDLEKPDSVNCLQLSNFTPYSRG----NVTFSI-----LTPGPNYRPG---YNNFY 471 Query: 239 SAKGLKEFFTLTDLRMRLLRPALGGTYVQRE---NLYKYFYAISNIEVIGRCKCNLHANL 295 + L+EF T +R G Y E NL +YA+ I + GRC+C+ HA+ Sbjct: 472 NTPSLQEFVKATQIRFHF-----HGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADN 526 Query: 296 CSMREGSLQCEC--EHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNC 353 C +C C E T G C +C + + +R G + + P C Sbjct: 527 CDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-----------C 575 Query: 354 ECYGHSNRCSYIDFLNVV----------TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403 +C HS C Y ++ C C+HNT G++C+ C+ ++R A+ Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI 635 Query: 404 NVCIECNCNQIGSVHDR--CNET-GFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQ 460 +VC C+C+ +G+ + C++ G C C+ +G +C+ C Y Q P+ C Sbjct: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCN 695 Query: 461 LLCQNGG------TCLQNQ-RCACPRGYTGVRCE 487 C G TC QN +C C G+RC+ Sbjct: 696 --CNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727 Score = 87.4 bits (215), Expect = 3e-17 Identities = 66/221 (29%), Positives = 94/221 (42%), Gaps = 45/221 (20%) Query: 287 CKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343 C+CNLH ++ C+ G QCEC+ G C C++NF L + + Sbjct: 747 CQCNLHGSVNKFCNPHSG--QCECKKEAKGLQCDTCRENFYG--------LDVTNCKACD 796 Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG--YYRNGSAELD 401 C TAGS C + +C CK N G+ C C G Y R ++ L Sbjct: 797 CDTAGSLPGTVCNAKTGQCI------------CKPNVEGRQCNKCLEGNFYLRQNNSFL- 843 Query: 402 DENVCIECNCNQIGSVHDR--CNE-TGFCECREGAAGPKCDDCLPTHYWR-----QGCYP 453 C+ CNC++ G+++ CN+ TG C C+ G G +C+ C P Y Q C Sbjct: 844 ----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHC-- 897 Query: 454 NVCDDDQLLCQNGGTCLQ-NQRCACPRGYTGVRCEQPRCDP 493 +C+ D L G C + +C C G RC Q C P Sbjct: 898 QMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ--CQP 936 Score = 82.0 bits (201), Expect = 1e-15 Identities = 63/219 (28%), Positives = 88/219 (40%), Gaps = 32/219 (14%) Query: 279 SNIEVIGRCKCNLHAN-----LCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSY 333 S I+V C C+ LC G QC C+ + +G C +C+ F Sbjct: 633 SAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELD--- 687 Query: 334 LPLPHG-SPNACATAGSF-GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG 391 P G SP C T+G+ G+ C+ +S +C CK N G C HC G Sbjct: 688 ---PDGCSPCNCNTSGTVDGDITCHQNSGQCK------------CKANVIGLRCDHCNFG 732 Query: 392 YYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYWRQG 450 + S ++ C C CN GSV+ CN +G CEC++ A G +CD C Y Sbjct: 733 FKFLRSF---NDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV 789 Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQ 488 CD D G C + +C C G +C + Sbjct: 790 TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828 Score = 63.5 bits (153), Expect = 4e-10 Identities = 46/178 (25%), Positives = 72/178 (40%), Gaps = 29/178 (16%) Query: 272 YKYFYAISNIEVIGRCKCN----LHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRS 327 ++Y I N + C+C+ L +C G QC C N G C +C+ F Sbjct: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISG--QCLCVPNRQGRRCNQCQPGFYISP 942 Query: 328 WRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQH 387 A LP +C T G+ + C+ + CV + GQ C Sbjct: 943 GNATGCLPC------SCHTTGAVNHI--------CNSL----TGQCVCQDASIAGQRCDQ 984 Query: 388 CRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPT 444 C+ Y+ C CNC+ G++++ C+ TG C C++ G KCD C+P+ Sbjct: 985 CKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPS 1038 >gi|219842259 usherin isoform A [Homo sapiens] Length = 1546 Score = 126 bits (317), Expect = 4e-29 Identities = 110/454 (24%), Positives = 193/454 (42%), Gaps = 74/454 (16%) Query: 66 ERFC-SHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANIT 124 +R+C ++ N NP+ AHP + D + + T W S ++ + L +T Sbjct: 316 QRYCIPNDAGDTADNRVSRLNPE-AHPLSFVNDND---VGTSWVSNVFTNI-TQLNQGVT 370 Query: 125 LSWNKTVELTDD------VVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMS 178 +S V+L + +++ F +PT + +++ +N W+ +Q++A +C AFGM Sbjct: 371 IS----VDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM- 424 Query: 179 ARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLE 238 + D+ + L ++ ++ +V F + + GP+ R Y Sbjct: 425 -KNNGDLEKPDSVNCLQLSNFTPYSRG----NVTFSI-----LTPGPNYRPG---YNNFY 471 Query: 239 SAKGLKEFFTLTDLRMRLLRPALGGTYVQRE---NLYKYFYAISNIEVIGRCKCNLHANL 295 + L+EF T +R G Y E NL +YA+ I + GRC+C+ HA+ Sbjct: 472 NTPSLQEFVKATQIRFHF-----HGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADN 526 Query: 296 CSMREGSLQCEC--EHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNC 353 C +C C E T G C +C + + +R G + + P C Sbjct: 527 CDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-----------C 575 Query: 354 ECYGHSNRCSYIDFLNVV----------TCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403 +C HS C Y ++ C C+HNT G++C+ C+ ++R A+ Sbjct: 576 QCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAI 635 Query: 404 NVCIECNCNQIGSVHDR--CNET-GFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQ 460 +VC C+C+ +G+ + C++ G C C+ +G +C+ C Y Q P+ C Sbjct: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCN 695 Query: 461 LLCQNGG------TCLQNQ-RCACPRGYTGVRCE 487 C G TC QN +C C G+RC+ Sbjct: 696 --CNTSGTVDGDITCHQNSGQCKCKANVIGLRCD 727 Score = 87.4 bits (215), Expect = 3e-17 Identities = 66/221 (29%), Positives = 94/221 (42%), Gaps = 45/221 (20%) Query: 287 CKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343 C+CNLH ++ C+ G QCEC+ G C C++NF L + + Sbjct: 747 CQCNLHGSVNKFCNPHSG--QCECKKEAKGLQCDTCRENFYG--------LDVTNCKACD 796 Query: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG--YYRNGSAELD 401 C TAGS C + +C CK N G+ C C G Y R ++ L Sbjct: 797 CDTAGSLPGTVCNAKTGQCI------------CKPNVEGRQCNKCLEGNFYLRQNNSFL- 843 Query: 402 DENVCIECNCNQIGSVHDR--CNE-TGFCECREGAAGPKCDDCLPTHYWR-----QGCYP 453 C+ CNC++ G+++ CN+ TG C C+ G G +C+ C P Y Q C Sbjct: 844 ----CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHC-- 897 Query: 454 NVCDDDQLLCQNGGTCLQ-NQRCACPRGYTGVRCEQPRCDP 493 +C+ D L G C + +C C G RC Q C P Sbjct: 898 QMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQ--CQP 936 Score = 82.0 bits (201), Expect = 1e-15 Identities = 63/219 (28%), Positives = 88/219 (40%), Gaps = 32/219 (14%) Query: 279 SNIEVIGRCKCNLHAN-----LCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSY 333 S I+V C C+ LC G QC C+ + +G C +C+ F Sbjct: 633 SAIDVCKPCDCDTVGTRNGSILCDQIGG--QCNCKRHVSGRQCNQCQNGFYNLQELD--- 687 Query: 334 LPLPHG-SPNACATAGSF-GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLG 391 P G SP C T+G+ G+ C+ +S +C CK N G C HC G Sbjct: 688 ---PDGCSPCNCNTSGTVDGDITCHQNSGQCK------------CKANVIGLRCDHCNFG 732 Query: 392 YYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPTHYWRQG 450 + S ++ C C CN GSV+ CN +G CEC++ A G +CD C Y Sbjct: 733 FKFLRSF---NDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDV 789 Query: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQ 488 CD D G C + +C C G +C + Sbjct: 790 TNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828 Score = 63.5 bits (153), Expect = 4e-10 Identities = 46/178 (25%), Positives = 72/178 (40%), Gaps = 29/178 (16%) Query: 272 YKYFYAISNIEVIGRCKCN----LHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRS 327 ++Y I N + C+C+ L +C G QC C N G C +C+ F Sbjct: 885 HRYNLTIDNFQHCQMCECDSLGTLPGTICDPISG--QCLCVPNRQGRRCNQCQPGFYISP 942 Query: 328 WRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQH 387 A LP +C T G+ + C+ + CV + GQ C Sbjct: 943 GNATGCLPC------SCHTTGAVNHI--------CNSL----TGQCVCQDASIAGQRCDQ 984 Query: 388 CRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGFCECREGAAGPKCDDCLPT 444 C+ Y+ C CNC+ G++++ C+ TG C C++ G KCD C+P+ Sbjct: 985 CKDHYFGFDP----QTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPS 1038 >gi|24308065 netrin 5 [Homo sapiens] Length = 489 Score = 115 bits (287), Expect = 1e-25 Identities = 56/167 (33%), Positives = 82/167 (49%), Gaps = 19/167 (11%) Query: 285 GRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344 GRC+C+ HA C+ R +C C H+TTGP C C+ + R WR P P+ C Sbjct: 155 GRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWR-----PATPRHPHPC 209 Query: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397 C C H+ RC + L ++ C C+H+T G+HC +C+ G++R+ S Sbjct: 210 LP------CSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPS 263 Query: 398 AELDDENVCIECNCNQIGSVHDRCNET-GFCECREGAAGPKCDDCLP 443 + C C C+ IG+ CN+T G C C+ G G C+ C P Sbjct: 264 QPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGP 310 Score = 79.7 bits (195), Expect = 6e-15 Identities = 70/234 (29%), Positives = 91/234 (38%), Gaps = 45/234 (19%) Query: 309 HNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFL 368 H+T GP ++ A S+L + G A AG G C+C+GH+ RC+ Sbjct: 124 HSTPGP-----------KATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCA--ARA 170 Query: 369 NVVTCVSCKHNTRGQHCQHCRLGY--YRNGSAELDDENVCIECNCNQIGSVHDRC----- 421 C C+H+T G C+ CR + + A + C+ C+CNQ RC Sbjct: 171 RPPRC-HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHAR---RCRFNSE 226 Query: 422 -------NETGFCE-CREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQ------NGG 467 G CE CR AG C C P +WR P CQ GG Sbjct: 227 LFRLSGGRSGGVCERCRHHTAGRHCHYCQP-GFWRDPSQPIFSRRACRACQCHPIGATGG 285 Query: 468 TCLQNQ-RCACPRGYTGVRCEQPRCDPADDDG---GLDCDRAPGAAPRPATLLG 517 TC Q +C C G TG+ C RC P + C R P A AT G Sbjct: 286 TCNQTSGQCTCKLGVTGLTCN--RCGPGYQQSRSPRMPCQRIPEATTTLATTPG 337 >gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] Length = 1111 Score = 97.4 bits (241), Expect = 3e-20 Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 21/160 (13%) Query: 353 CECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 407 C+C G S +C + L+ T C++C NT G HC+ C+ G+YR+ + + C+ Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82 Query: 408 ECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467 CNCN GS+ RC+ +G C C+ G G +CD CLP + C DQ L + Sbjct: 83 PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKC 139 Query: 468 TC--------LQNQRCACPRGYTGVRCEQPRCDPADDDGG 499 C RC C TG RC++ R + DGG Sbjct: 140 DCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGG 179 Score = 63.2 bits (152), Expect = 6e-10 Identities = 41/141 (29%), Positives = 54/141 (38%), Gaps = 29/141 (20%) Query: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP---HGSPNACATAGSFGNCECYGH----- 358 C TG C C A Y P HG C C+C + Sbjct: 484 CPPGVTGARCELC----------ADGYFGDPFGEHGPVRPCQP------CQCNNNVDPSA 527 Query: 359 SNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVH 418 S C + C+ C HNT G +C C+ GY+ + A + + C CNCN +GS Sbjct: 528 SGNCDRL----TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP-NPADKCRACNCNPMGSEP 582 Query: 419 DRCNETGFCECREGAAGPKCD 439 C G C C+ G GP C+ Sbjct: 583 VGCRSDGTCVCKPGFGGPNCE 603 Score = 55.8 bits (133), Expect = 9e-08 Identities = 42/124 (33%), Positives = 53/124 (42%), Gaps = 14/124 (11%) Query: 370 VVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCEC 429 V C+ C +GQ CQ C GY R+ SA L CI CNC G+ +TG C Sbjct: 379 VEQCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQGGGACDP---DTGDCYS 433 Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC-----LQNQRC-ACPRGYTG 483 + +C DC P ++ P C C NG +C + C CP G TG Sbjct: 434 GDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVTG 490 Query: 484 VRCE 487 RCE Sbjct: 491 ARCE 494 Score = 55.8 bits (133), Expect = 9e-08 Identities = 51/195 (26%), Positives = 67/195 (34%), Gaps = 15/195 (7%) Query: 303 LQCECEHN-TTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNR 361 + C C+ PD G C P G N S C C+ + Sbjct: 414 IPCNCQGGGACDPDTGDCYSGDENPDIECAD---CPIGFYNDPHDPRSCKPCPCHNGFS- 469 Query: 362 CSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ--IGSVHD 419 CS + V C +C G C+ C GY+ + E C C CN S Sbjct: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529 Query: 420 RCNE-TGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL-CQNGGT----CLQN 472 C+ TG C +C AG CD C Y+ PN D + C G+ C + Sbjct: 530 NCDRLTGRCLKCIHNTAGIYCDQC-KAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD 588 Query: 473 QRCACPRGYTGVRCE 487 C C G+ G CE Sbjct: 589 GTCVCKPGFGGPNCE 603 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 23/127 (18%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C CN +L + + S +C C+ TG C +C F + + S C Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405 AG G C+ + RC CK G+ C CR GYY LD N Sbjct: 144 AGIAGPCD----AGRC------------VCKPAVTGERCDRCRSGYY-----NLDGGNPE 182 Query: 406 -CIECNC 411 C +C C Sbjct: 183 GCTQCFC 189 Score = 35.0 bits (79), Expect = 0.17 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 16/59 (27%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRC 362 +C C+ TG C +C+ Y L G+P C C CYGHS C Sbjct: 154 RCVCKPAVTGERCDRCRSG----------YYNLDGGNPEGCT------QCFCYGHSASC 196 >gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] Length = 1193 Score = 97.4 bits (241), Expect = 3e-20 Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 21/160 (13%) Query: 353 CECYGHSNRCSYIDFLNVVT-----CVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCI 407 C+C G S +C + L+ T C++C NT G HC+ C+ G+YR+ + + C+ Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR-----ERDRCL 82 Query: 408 ECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGG 467 CNCN GS+ RC+ +G C C+ G G +CD CLP + C DQ L + Sbjct: 83 PCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLLDSKC 139 Query: 468 TC--------LQNQRCACPRGYTGVRCEQPRCDPADDDGG 499 C RC C TG RC++ R + DGG Sbjct: 140 DCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGG 179 Score = 63.2 bits (152), Expect = 6e-10 Identities = 41/141 (29%), Positives = 54/141 (38%), Gaps = 29/141 (20%) Query: 307 CEHNTTGPDCGKCKKNFRTRSWRAGSYLPLP---HGSPNACATAGSFGNCECYGH----- 358 C TG C C A Y P HG C C+C + Sbjct: 484 CPPGVTGARCELC----------ADGYFGDPFGEHGPVRPCQP------CQCNNNVDPSA 527 Query: 359 SNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVH 418 S C + C+ C HNT G +C C+ GY+ + A + + C CNCN +GS Sbjct: 528 SGNCDRL----TGRCLKCIHNTAGIYCDQCKAGYFGDPLAP-NPADKCRACNCNPMGSEP 582 Query: 419 DRCNETGFCECREGAAGPKCD 439 C G C C+ G GP C+ Sbjct: 583 VGCRSDGTCVCKPGFGGPNCE 603 Score = 55.8 bits (133), Expect = 9e-08 Identities = 42/124 (33%), Positives = 53/124 (42%), Gaps = 14/124 (11%) Query: 370 VVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCEC 429 V C+ C +GQ CQ C GY R+ SA L CI CNC G+ +TG C Sbjct: 379 VEQCI-CPVGYKGQFCQDCASGYKRD-SARLGPFGTCIPCNCQGGGACDP---DTGDCYS 433 Query: 430 REGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC-----LQNQRC-ACPRGYTG 483 + +C DC P ++ P C C NG +C + C CP G TG Sbjct: 434 GDENPDIECADC-PIGFYNDPHDPRSC--KPCPCHNGFSCSVMPETEEVVCNNCPPGVTG 490 Query: 484 VRCE 487 RCE Sbjct: 491 ARCE 494 Score = 55.8 bits (133), Expect = 9e-08 Identities = 51/195 (26%), Positives = 67/195 (34%), Gaps = 15/195 (7%) Query: 303 LQCECEHN-TTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNR 361 + C C+ PD G C P G N S C C+ + Sbjct: 414 IPCNCQGGGACDPDTGDCYSGDENPDIECAD---CPIGFYNDPHDPRSCKPCPCHNGFS- 469 Query: 362 CSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQ--IGSVHD 419 CS + V C +C G C+ C GY+ + E C C CN S Sbjct: 470 CSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529 Query: 420 RCNE-TGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLL-CQNGGT----CLQN 472 C+ TG C +C AG CD C Y+ PN D + C G+ C + Sbjct: 530 NCDRLTGRCLKCIHNTAGIYCDQC-KAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD 588 Query: 473 QRCACPRGYTGVRCE 487 C C G+ G CE Sbjct: 589 GTCVCKPGFGGPNCE 603 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 23/127 (18%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C CN +L + + S +C C+ TG C +C F + + S C Sbjct: 84 CNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENV- 405 AG G C+ + RC CK G+ C CR GYY LD N Sbjct: 144 AGIAGPCD----AGRC------------VCKPAVTGERCDRCRSGYY-----NLDGGNPE 182 Query: 406 -CIECNC 411 C +C C Sbjct: 183 GCTQCFC 189 Score = 35.0 bits (79), Expect = 0.17 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 16/59 (27%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRC 362 +C C+ TG C +C+ Y L G+P C C CYGHS C Sbjct: 154 RCVCKPAVTGERCDRCRSG----------YYNLDGGNPEGCT------QCFCYGHSASC 196 >gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] Length = 4391 Score = 95.5 bits (236), Expect = 1e-19 Identities = 54/176 (30%), Positives = 77/176 (43%), Gaps = 16/176 (9%) Query: 286 RCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345 RC C+ H+ C G+ Q C+H+T GP C +C+ G Y G+P C Sbjct: 1158 RCSCHGHSEACEPETGACQ-GCQHHTEGPRCEQCQP---------GYYGDAQRGTPQDCQ 1207 Query: 346 TAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRN---GSAELDD 402 +G+ G + ++D TC +C G+HC+ C GYY N G D Sbjct: 1208 LCPCYGD-PAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRD 1266 Query: 403 ENVC--IECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVC 456 V I CNC+ GSV +C+ G C+C+ G C C P H+ P+ C Sbjct: 1267 SQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGC 1322 Score = 64.3 bits (155), Expect = 3e-10 Identities = 58/222 (26%), Positives = 79/222 (35%), Gaps = 44/222 (19%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363 QC C GP C C + TR+ +G YL G+ C C+GHS C Sbjct: 1125 QCSCPPGYRGPSCQDCDTGY-TRT-PSGLYL-------------GTCERCSCHGHSEACE 1169 Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNC---NQIGSVHDR 420 C C+H+T G C+ C+ GYY G A+ C C C G Sbjct: 1170 ----PETGACQGCQHHTEGPRCEQCQPGYY--GDAQRGTPQDCQLCPCYGDPAAGQAAHT 1223 Query: 421 C----NETGFCE-CREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQL------LCQNGGT- 468 C + C+ C G +G C+ C P +Y D Q+ C G+ Sbjct: 1224 CFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSV 1283 Query: 469 ---CLQNQRCACPRGYTGVRCEQPR-----CDPADDDGGLDC 502 C +C C G+ C R ++ DG L C Sbjct: 1284 SSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC 1325 Score = 63.5 bits (153), Expect = 4e-10 Identities = 45/177 (25%), Positives = 64/177 (36%), Gaps = 26/177 (14%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C CN HA+ C G C+HNT GP C KCK F + +A + P P A+ Sbjct: 764 CNCNGHASSCDPVYGHC-LNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDAS 822 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVC 406 C ++D TC +C G+ C+ C GY N + Sbjct: 823 RRFSDTC----------FLDTDGQATCDACAPGYTGRRCESCAPGYEGNP--------IQ 864 Query: 407 IECNCNQIGSVHDRCNETGF-------CECREGAAGPKCDDCLPTHYWRQGCYPNVC 456 C + RC+E G C C+ G C++C + P+ C Sbjct: 865 PGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGC 921 Score = 62.0 bits (149), Expect = 1e-09 Identities = 48/198 (24%), Positives = 75/198 (37%), Gaps = 35/198 (17%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363 +C C +G C C +F TR G YL G+ C C GH++ C Sbjct: 730 ECRCPIGYSGLSCESCDAHF-TRV-PGGPYL-------------GTCSGCNCNGHASSCD 774 Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423 + C++C+HNT G C C+ G++ G A C C C I + R ++ Sbjct: 775 PV----YGHCLNCQHNTEGPQCNKCKAGFF--GDAMKATATSCRPCPCPYIDASR-RFSD 827 Query: 424 TGFCE---------CREGAAGPKCDDCLPTHYW---RQGCYPNVCDDDQLLC-QNGGTCL 470 T F + C G G +C+ C P + + G + + + C + G Sbjct: 828 TCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGT 887 Query: 471 QNQRCACPRGYTGVRCEQ 488 + C C G C + Sbjct: 888 SGEACRCKNNVVGRLCNE 905 Score = 58.5 bits (140), Expect = 1e-08 Identities = 49/169 (28%), Positives = 68/169 (40%), Gaps = 30/169 (17%) Query: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCS 363 +C C G C C + R GS L L H C CEC GHS+ C Sbjct: 1529 ECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGH-----CEL------CECNGHSDLCH 1573 Query: 364 YIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE 423 C C+HN G+ C+ C GYY + +A ++ C C C + + + + Sbjct: 1574 P----ETGACSQCQHNAAGEFCELCAPGYYGDATAGTPED--CQPCAC-PLTNPENMFSR 1626 Query: 424 TGFCECREGAAGPKCDDCLP--THYWRQGCYPNVCDDDQLLCQNGGTCL 470 T CE GA G +C C P T + + C P + + GG CL Sbjct: 1627 T--CESL-GAGGYRCTACEPGYTGQYCEQCGPGYVGNPSV---QGGQCL 1669 Score = 56.6 bits (135), Expect = 5e-08 Identities = 53/167 (31%), Positives = 66/167 (39%), Gaps = 28/167 (16%) Query: 368 LNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGF 426 L V C SC RG CQ C GY R S C C+C+ + C ETG Sbjct: 1121 LEVEQC-SCPPGYRGPSCQDCDTGYTRTPSGLY--LGTCERCSCH---GHSEACEPETGA 1174 Query: 427 CE-CREGAAGPKCDDCLPTHY------WRQGCYPNVCDDDQLLCQNGGTCL----QNQRC 475 C+ C+ GP+C+ C P +Y Q C C D Q TC + C Sbjct: 1175 CQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTC 1234 Query: 476 -ACPRGYTGVRCEQPRCDP---ADDDGGLDCDRAPGAAPRPATLLGC 518 AC G++G CE RC P + G C R P P +GC Sbjct: 1235 DACSPGHSGRHCE--RCAPGYYGNPSQGQPCQR-DSQVPGP---IGC 1275 Score = 54.3 bits (129), Expect = 3e-07 Identities = 49/139 (35%), Positives = 55/139 (39%), Gaps = 21/139 (15%) Query: 368 LNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN-ETGF 426 L V C C G CQ C GY R GS C C CN D C+ ETG Sbjct: 1525 LEVEEC-RCPPGYIGLSCQDCAPGYTRTGSGLYLGH--CELCECN---GHSDLCHPETGA 1578 Query: 427 C-ECREGAAGPKCDDCLPTHYWR------QGCYPNVCDDDQLLCQNGGTCLQ----NQRC 475 C +C+ AAG C+ C P +Y + C P C TC RC Sbjct: 1579 CSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRC 1638 Query: 476 -ACPRGYTGVRCEQPRCDP 493 AC GYTG CEQ C P Sbjct: 1639 TACEPGYTGQYCEQ--CGP 1655 Score = 46.6 bits (109), Expect = 6e-05 Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 11/113 (9%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C+CN H++LC G+ +C+HN G C C G Y G+P C Sbjct: 1563 CECNGHSDLCHPETGACS-QCQHNAAGEFCELC---------APGYYGDATAGTPEDCQP 1612 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAE 399 S C + C +C+ GQ+C+ C GY N S + Sbjct: 1613 CACPLTNPENMFSRTCESLG-AGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQ 1664 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 17/88 (19%) Query: 406 CIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQN 465 C + C G HD + + C C G G +C+ H C+P C D Sbjct: 3848 CRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALH-----CHPEACGPD------ 3896 Query: 466 GGTCL-----QNQRCACPRGYTGVRCEQ 488 TC+ + C C G +G+RCE+ Sbjct: 3897 -ATCVNRPDGRGYTCRCHLGRSGLRCEE 3923 Score = 40.0 bits (92), Expect = 0.005 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 22/84 (26%) Query: 420 RCNETGFCE---CREGAAGPKCDDCLPTHYW------RQGCYPNVCDDDQLLCQ------ 464 +C ++ CE C+ GA C+P + R G ++C+ ++ CQ Sbjct: 4101 QCYDSSPCERQPCQHGAT------CMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCL 4154 Query: 465 NGGTCLQNQRCACPRGYTGVRCEQ 488 +GGTC Q RC C G++G RC+Q Sbjct: 4155 HGGTC-QGTRCLCLPGFSGPRCQQ 4177 Score = 33.5 bits (75), Expect = 0.49 Identities = 26/80 (32%), Positives = 30/80 (37%), Gaps = 10/80 (12%) Query: 419 DRCNETGFCECREGAAGPKCDDCLPTHYWR--QGCYPNVCDDDQLLCQNGGTCLQNQRCA 476 D E C C G GP C DC T Y R G Y C ++ C + + A Sbjct: 1118 DPALEVEQCSCPPGYRGPSCQDC-DTGYTRTPSGLYLGTC--ERCSCHGHSEACEPETGA 1174 Query: 477 ---CPRGYTGVRCEQPRCDP 493 C G RCEQ C P Sbjct: 1175 CQGCQHHTEGPRCEQ--CQP 1192 Score = 30.0 bits (66), Expect = 5.5 Identities = 32/102 (31%), Positives = 33/102 (32%), Gaps = 19/102 (18%) Query: 420 RCNETGFCECREGAAGPKCDDCLPTHYWRQG-------CYPNVCDDDQLLCQ-NGGTCLQ 471 R E C C G G C DC P Y R G C C+ LC G C Q Sbjct: 1523 RALEVEECRCPPGYIGLSCQDCAP-GYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQ 1581 Query: 472 NQRCACPRGYTGVRCEQPRCDP---ADDDGGLDCDRAPGAAP 510 C G CE C P D G D P A P Sbjct: 1582 -----CQHNAAGEFCE--LCAPGYYGDATAGTPEDCQPCACP 1616 >gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] Length = 639 Score = 75.5 bits (184), Expect = 1e-13 Identities = 56/203 (27%), Positives = 83/203 (40%), Gaps = 35/203 (17%) Query: 319 CKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTC----- 373 C+ N +++ YLPL N + C CS + LNV C Sbjct: 211 CESNLKSK------YLPLTQPVMNLRVSEAVKTEYVC-----NCSVVGSLNVNRCNQTTG 259 Query: 374 -VSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREG 432 C+ +G HC+ C+ G+Y N ++ L C C+C+ G++ CN +G C+C+ G Sbjct: 260 QCECRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIPCNSSGKCQCKVG 314 Query: 433 AAGPKCDDCLPTHYW--RQGCYPNVCDDDQLLCQN-GGTCLQNQRCACPRGYTGVRCEQP 489 G CD C +Y + GC P C++ C G CL C G CE+ Sbjct: 315 VIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLN-----CQENSKGNHCEE- 368 Query: 490 RCDPA---DDDGGLDCDRAPGAA 509 C D +C R P +A Sbjct: 369 -CKEGFYQSPDATKECLRCPCSA 390 Score = 73.2 bits (178), Expect = 6e-13 Identities = 53/193 (27%), Positives = 81/193 (41%), Gaps = 50/193 (25%) Query: 278 ISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPL- 336 + N V+G +L+ N C+ G QCEC G C CK+ F ++ +G P Sbjct: 240 VCNCSVVG----SLNVNRCNQTTG--QCECRPGYQGLHCETCKEGFYL-NYTSGLCQPCD 292 Query: 337 --PHGSPNACATAGSFGNCEC----------------YGHS----------NRCSYIDFL 368 PHG+ S G C+C YG S NR + D L Sbjct: 293 CSPHGA--LSIPCNSSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDAL 350 Query: 369 NVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCE 428 C++C+ N++G HC+ C+ G+Y++ A + C+ C C+ + S TG C Sbjct: 351 -TGACLNCQENSKGNHCEECKEGFYQSPDATKE----CLRCPCSAVTS-------TGSCS 398 Query: 429 CREGAAGPKCDDC 441 + P+CD C Sbjct: 399 IKSSELEPECDQC 411 Score = 52.4 bits (124), Expect = 1e-06 Identities = 46/189 (24%), Positives = 74/189 (39%), Gaps = 38/189 (20%) Query: 287 CKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACAT 346 C+CN + C G+ C+ N+ G C +CK+ F L P C+ Sbjct: 338 CQCNNRSASCDALTGAC-LNCQENSKGNHCEECKEGFYQSPDATKECLRCP------CSA 390 Query: 347 AGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVC 406 S G+C S + S ++ C CK G +C C GYY + +++C Sbjct: 391 VTSTGSC-----SIKSSELE----PECDQCKDGYIGPNCNKCENGYY-------NFDSIC 434 Query: 407 IECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCL--PTHYWRQGCYPNVCDDDQLLCQ 464 +C C+ G V D C+ G +C +CL T +W + C D + Sbjct: 435 RKCQCH--GHV-DPVKTPKICKPESG----ECINCLHNTTGFWCENCLEGYVHDLE---- 483 Query: 465 NGGTCLQNQ 473 G C++ + Sbjct: 484 --GNCIKKE 490 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 27/114 (23%) Query: 286 RCKCNLHANL--CSMREGSLQCECEH---NTTGPDCGKCKKNFRTRSWRAGSYLPLPHGS 340 RC C+ + CS++ L+ EC+ GP+C KC+ + + Sbjct: 385 RCPCSAVTSTGSCSIKSSELEPECDQCKDGYIGPNCNKCENGY--------------YNF 430 Query: 341 PNACATAGSFGNCECYGHSNRCSYIDFLNVVT--CVSCKHNTRGQHCQHCRLGY 392 + C C+C+GH + + C++C HNT G C++C GY Sbjct: 431 DSICR------KCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGY 478 >gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] Length = 1668 Score = 74.7 bits (182), Expect = 2e-13 Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%) Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412 C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C Sbjct: 78 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 128 Query: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469 S C G C C+ G G +C+ C P ++ + C C +C Sbjct: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 180 Query: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528 N + TG Q +P D +CD TLL L +G RL Sbjct: 181 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 233 Score = 69.3 bits (168), Expect = 8e-12 Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%) Query: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345 C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC Sbjct: 78 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 126 Query: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402 SF C G RC SCK G C+ C GY+ N Sbjct: 127 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 171 Query: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441 C C+CN Q+GS H + E ++ + +CDDC Sbjct: 172 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213 Score = 53.1 bits (126), Expect = 6e-07 Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 23/151 (15%) Query: 354 ECYGHSNRCSYIDFLNVVTCVSCKHN-TRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412 +C G+S++ + FL + + + Q C GYYR+ C+ CNCN Sbjct: 24 QCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGR--CVPCNCN 81 Query: 413 QIGSVHDRCNETGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT--- 468 G + + +G C C+ AG C+ C ++G Y N C T Sbjct: 82 --GHSNQCQDGSGICVNCQHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSF 133 Query: 469 ---CLQN---QRCACPRGYTGVRCEQPRCDP 493 C+ N RC+C GYTG +CE RC P Sbjct: 134 ATGCVVNGGDVRCSCKAGYTGTQCE--RCAP 162 >gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] Length = 1724 Score = 74.7 bits (182), Expect = 2e-13 Identities = 53/179 (29%), Positives = 71/179 (39%), Gaps = 26/179 (14%) Query: 353 CECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412 C C GHSN+C D + CV+C+HNT G+HC+ C+ GYY N C C C Sbjct: 78 CNCNGHSNQCQ--DGSGI--CVNCQHNTAGEHCERCQEGYYGNAV-----HGSCRACPCP 128 Query: 413 QIGSVHDRCNETG---FCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTC 469 S C G C C+ G G +C+ C P ++ + C C +C Sbjct: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP----C----SC 180 Query: 470 LQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARL 528 N + TG Q +P D +CD TLL L +G RL Sbjct: 181 NSNGQLGSCHPLTGDCINQ---EPKDSSPAEECDDCDSCV---MTLLNDLATMGEQLRL 233 Score = 69.3 bits (168), Expect = 8e-12 Identities = 51/162 (31%), Positives = 67/162 (41%), Gaps = 33/162 (20%) Query: 287 CKCNLHANLCSMREGSLQC-ECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACA 345 C CN H+N C ++GS C C+HNT G C +C++ G Y HGS AC Sbjct: 78 CNCNGHSNQC--QDGSGICVNCQHNTAGEHCERCQE---------GYYGNAVHGSCRACP 126 Query: 346 T--AGSFG-NCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDD 402 SF C G RC SCK G C+ C GY+ N Sbjct: 127 CPHTNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KF 171 Query: 403 ENVCIECNCN---QIGSVHDRCNETGFCECREGAAGPKCDDC 441 C C+CN Q+GS H + E ++ + +CDDC Sbjct: 172 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213 Score = 53.1 bits (126), Expect = 6e-07 Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 23/151 (15%) Query: 354 ECYGHSNRCSYIDFLNVVTCVSCKHN-TRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412 +C G+S++ + FL + + + Q C GYYR+ C+ CNCN Sbjct: 24 QCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGR--CVPCNCN 81 Query: 413 QIGSVHDRCNETGFC-ECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGT--- 468 G + + +G C C+ AG C+ C ++G Y N C T Sbjct: 82 --GHSNQCQDGSGICVNCQHNTAGEHCERC------QEGYYGNAVHGSCRACPCPHTNSF 133 Query: 469 ---CLQN---QRCACPRGYTGVRCEQPRCDP 493 C+ N RC+C GYTG +CE RC P Sbjct: 134 ATGCVVNGGDVRCSCKAGYTGTQCE--RCAP 162 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.466 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,183,621 Number of Sequences: 37866 Number of extensions: 1313079 Number of successful extensions: 5617 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 104 Number of HSP's successfully gapped in prelim test: 181 Number of HSP's that attempted gapping in prelim test: 3079 Number of HSP's gapped (non-prelim): 1234 length of query: 530 length of database: 18,247,518 effective HSP length: 107 effective length of query: 423 effective length of database: 14,195,856 effective search space: 6004847088 effective search space used: 6004847088 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.