Search of human proteins with 189571693

Search of human proteins with 189571693

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189571693 potassium channel tetramerisation domain
containing 6 [Homo sapiens]
         (237 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189571693 potassium channel tetramerisation domain containing...   498   e-141
gi|189571691 potassium channel tetramerisation domain containing...   498   e-141
gi|71143104 potassium channel tetramerisation domain containing ...   150   9e-37
gi|194018443 potassium channel tetramerisation domain containing...   112   3e-25
gi|194018441 potassium channel tetramerisation domain containing...   112   3e-25
gi|194018439 potassium channel tetramerisation domain containing...   112   3e-25
gi|218505694 potassium channel tetramerisation domain containing...   110   1e-24
gi|209969708 potassium channel tetramerisation domain containing...   110   1e-24
gi|40217617 potassium channel tetramerisation domain containing ...   110   1e-24
gi|146198864 potassium channel tetramerisation domain containing...    97   9e-21
gi|23308551 potassium channel tetramerisation domain containing ...    92   5e-19
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       91   1e-18
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       91   1e-18
gi|19923973 potassium channel tetramerisation domain containing ...    85   5e-17
gi|38198663 potassium channel tetramerisation domain containing ...    83   2e-16
gi|55926200 potassium channel tetramerisation domain containing ...    80   2e-15
gi|142356950 potassium channel tetramerisation domain containing...    76   2e-14
gi|45387953 potassium channel tetramerization domain containing ...    75   5e-14
gi|51036594 potassium channel tetramerisation domain containing ...    74   1e-13
gi|46255026 potassium channel tetramerisation domain containing ...    74   1e-13
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    72   4e-13
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  69   4e-12
gi|13994353 potassium channel tetramerisation domain containing ...    69   5e-12
gi|169234778 potassium channel tetramerisation domain containing...    68   8e-12
gi|30578412 potassium channel tetramerisation domain containing ...    64   1e-10
gi|9506651 potassium channel tetramerisation domain containing 5...    60   2e-09
gi|155369221 potassium channel tetramerisation domain containing...    58   6e-09
gi|39753959 potassium channel tetramerisation domain containing ...    58   8e-09
gi|27436981 potassium voltage-gated channel, Shal-related subfam...    57   2e-08
gi|27436984 potassium voltage-gated channel, Shal-related subfam...    55   5e-08

>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score =  498 bits (1281), Expect = e-141
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR 60
           MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR
Sbjct: 1   MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR 60

Query: 61  DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV 120
           DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV
Sbjct: 61  DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV 120

Query: 121 VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG 180
           VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG
Sbjct: 121 VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG 180

Query: 181 PCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD 237
           PCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD
Sbjct: 181 PCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD 237


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score =  498 bits (1281), Expect = e-141
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR 60
           MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR
Sbjct: 1   MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR 60

Query: 61  DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV 120
           DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV
Sbjct: 61  DGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEV 120

Query: 121 VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG 180
           VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG
Sbjct: 121 VELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFG 180

Query: 181 PCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD 237
           PCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD
Sbjct: 181 PCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD 237


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score =  150 bits (379), Expect = 9e-37
 Identities = 76/119 (63%), Positives = 87/119 (73%), Gaps = 11/119 (9%)

Query: 10  MTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVL 69
           M+DP+TLNVGG LYTTSL TLT +PDSMLGAMF G  PT RD QGN FIDRDG +FRY+L
Sbjct: 1   MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 60

Query: 70  NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRK 128
           NFLRTS L LP DF+E  LLR+EADFYQ++PLI+ L            E+ VELS   K
Sbjct: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ-----------EKEVELSKAEK 108


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score =  112 bits (280), Expect = 3e-25
 Identities = 52/92 (56%), Positives = 72/92 (78%), Gaps = 1/92 (1%)

Query: 13  PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
           PV ++VGGH+YT+SL TLT+YPDS +  +F G  P   D  + +YFIDRDG +FRYVL+F
Sbjct: 57  PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116

Query: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQ 103
           LRTS+L LP DFK+F LL +EA +YQ++P+++
Sbjct: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVR 148


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score =  112 bits (280), Expect = 3e-25
 Identities = 52/92 (56%), Positives = 72/92 (78%), Gaps = 1/92 (1%)

Query: 13  PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
           PV ++VGGH+YT+SL TLT+YPDS +  +F G  P   D  + +YFIDRDG +FRYVL+F
Sbjct: 57  PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116

Query: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQ 103
           LRTS+L LP DFK+F LL +EA +YQ++P+++
Sbjct: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVR 148


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score =  112 bits (280), Expect = 3e-25
 Identities = 52/92 (56%), Positives = 72/92 (78%), Gaps = 1/92 (1%)

Query: 13  PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
           PV ++VGGH+YT+SL TLT+YPDS +  +F G  P   D  + +YFIDRDG +FRYVL+F
Sbjct: 57  PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116

Query: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQ 103
           LRTS+L LP DFK+F LL +EA +YQ++P+++
Sbjct: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVR 148


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score =  110 bits (274), Expect = 1e-24
 Identities = 49/91 (53%), Positives = 72/91 (79%), Gaps = 1/91 (1%)

Query: 13  PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
           PV ++VGGH+YT+SL TLT+YP+S +G +F G  P   D  + +YFIDRDG +FRY+LNF
Sbjct: 639 PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 698

Query: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLI 102
           LRTS+L +P DFK++ LL +EA ++Q++P++
Sbjct: 699 LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 729


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score =  110 bits (274), Expect = 1e-24
 Identities = 49/91 (53%), Positives = 72/91 (79%), Gaps = 1/91 (1%)

Query: 13  PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
           PV ++VGGH+YT+SL TLT+YP+S +G +F G  P   D  + +YFIDRDG +FRY+LNF
Sbjct: 31  PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 90

Query: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLI 102
           LRTS+L +P DFK++ LL +EA ++Q++P++
Sbjct: 91  LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score =  110 bits (274), Expect = 1e-24
 Identities = 49/91 (53%), Positives = 72/91 (79%), Gaps = 1/91 (1%)

Query: 13  PVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDP-QGNYFIDRDGPLFRYVLNF 71
           PV ++VGGH+YT+SL TLT+YP+S +G +F G  P   D  + +YFIDRDG +FRY+LNF
Sbjct: 31  PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 90

Query: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLI 102
           LRTS+L +P DFK++ LL +EA ++Q++P++
Sbjct: 91  LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 97.4 bits (241), Expect = 9e-21
 Identities = 48/90 (53%), Positives = 62/90 (68%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           +TLNVGG+LY T   TLT+YPD+ L  +  G      D  G+YFIDRDG LFR+VLNFLR
Sbjct: 35  MTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLR 94

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQ 103
             EL LP  F+E  LL +EA+F+Q++ L +
Sbjct: 95  NGELLLPEGFRENQLLAQEAEFFQLKGLAE 124


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 91.7 bits (226), Expect = 5e-19
 Identities = 68/211 (32%), Positives = 105/211 (49%), Gaps = 23/211 (10%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           V LN+GG  +TT L+TL  Y D+ML AMF G      D +G YFIDRDG  F  VLNFLR
Sbjct: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPL--------------YPMDTFEE 119
           + +L      +    + KEA +Y I PL++ L + +PL              Y  D  E 
Sbjct: 113 SGDLP---PRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLER 169

Query: 120 VVELSSTRKLSKYSN----PVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQV 175
           +VE++  R + + +      V V   ++ IT     LL  +    ++ +  + +   C+V
Sbjct: 170 IVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFE-HHCEV 228

Query: 176 SFTFGPCDYHQEVSLRVH-LMEYITKQGFTI 205
             +FGP +   +V   +H L+  ++ QG T+
Sbjct: 229 DVSFGPWEAVADVYDLLHCLVTDLSAQGLTV 259


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 54/152 (35%), Positives = 82/152 (53%), Gaps = 6/152 (3%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           VTLNVGG ++TT  +T+ ++P S L  M  G     +   G  F+DRDG LF ++L+FLR
Sbjct: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSST-----RK 128
           T +L LP +F ++  L++EA FY++  L+  LN P  L P     EV  LS       R 
Sbjct: 67  THQLLLPTEFSDYLRLQREALFYELRSLVDLLN-PYLLQPRPALVEVHFLSRNTQAFFRV 125

Query: 129 LSKYSNPVAVIITQLTITTKVHSLLEGISNYF 160
               S  + ++  ++T+ T+  S      N+F
Sbjct: 126 FGSCSKTIEMLTGRITVFTEQPSAPTWNGNFF 157


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 54/152 (35%), Positives = 82/152 (53%), Gaps = 6/152 (3%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           VTLNVGG ++TT  +T+ ++P S L  M  G     +   G  F+DRDG LF ++L+FLR
Sbjct: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSST-----RK 128
           T +L LP +F ++  L++EA FY++  L+  LN P  L P     EV  LS       R 
Sbjct: 67  THQLLLPTEFSDYLRLQREALFYELRSLVDLLN-PYLLQPRPALVEVHFLSRNTQAFFRV 125

Query: 129 LSKYSNPVAVIITQLTITTKVHSLLEGISNYF 160
               S  + ++  ++T+ T+  S      N+F
Sbjct: 126 FGSCSKTIEMLTGRITVFTEQPSAPTWNGNFF 157


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 44/103 (42%), Positives = 65/103 (63%), Gaps = 2/103 (1%)

Query: 9   MMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPT--ARDPQGNYFIDRDGPLFR 66
           +  D V LNVGG +Y T   T+   PDS+L  MF    P   ARD +G +F+DRDG LFR
Sbjct: 31  LFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFR 90

Query: 67  YVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPK 109
           Y+L++LR  +L LP  F E   L++EA+++++  L++ L  P+
Sbjct: 91  YILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQ 133


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 82.8 bits (203), Expect = 2e-16
 Identities = 44/102 (43%), Positives = 61/102 (59%), Gaps = 9/102 (8%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTA---------RDPQGNYFIDRDGPL 64
           V LNVGG +Y T  +TL   PDS L +MF    P           RD +  +FIDRDG L
Sbjct: 46  VELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFL 105

Query: 65  FRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLN 106
           FRYVL++LR  +L LP  F E + L +EA+++Q+  L++ L+
Sbjct: 106 FRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLS 147


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 48/123 (39%), Positives = 70/123 (56%), Gaps = 9/123 (7%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTA----RDPQGNYFIDRDGPLFRYVL 69
           V LNVGG +Y T  +TL   P S+L  MF     TA    +D +G +FIDRDG LFRY+L
Sbjct: 27  VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86

Query: 70  NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMD-----TFEEVVELS 124
           ++LR  ++ LP  F E   L++EA+++Q+  L++ L   +     D      FE+  + S
Sbjct: 87  DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGS 146

Query: 125 STR 127
            TR
Sbjct: 147 DTR 149


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 58/206 (28%), Positives = 100/206 (48%), Gaps = 18/206 (8%)

Query: 10  MTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVL 69
           M+  V LNVGG  +TT+L TL ++P S L  MF      + D +G +FIDR    FR +L
Sbjct: 31  MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPIL 90

Query: 70  NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKL 129
           ++LRT ++      +    + +EA FY+I+PL++ L D   ++     E+V       ++
Sbjct: 91  DYLRTGQVPT----QHIPEVYREAQFYEIKPLVKLLEDMPQIFG----EQVSRKQFLLQV 142

Query: 130 SKYSNPVAVIITQL---TITTKVHSLL------EGISNYFTKWNKHMMDTRDCQVSFTFG 180
             YS  + +++       IT +  S+L      E    Y+++    + D +  +    FG
Sbjct: 143 PGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFG 202

Query: 181 PCDYHQEVSLRVHLMEY-ITKQGFTI 205
           P     + S  +H +E  I  QG+ +
Sbjct: 203 PWKAVLDNSDLMHCLEMDIKAQGYKV 228


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 46/134 (34%), Positives = 74/134 (55%), Gaps = 3/134 (2%)

Query: 12  DPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNF 71
           D + LNVGG +YT    +L R+ DSML +MF G FP   D  G   IDRDG LF+Y+L++
Sbjct: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71

Query: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSK 131
           L   E+ +P D +    L++EAD++ I P    L+D      M+T+     +   + L+ 
Sbjct: 72  LH-GEVQIPTDEQTRIALQEEADYFGI-PYPYSLSD-HLANEMETYSLRSNIELKKALTD 128

Query: 132 YSNPVAVIITQLTI 145
           + +   ++  + T+
Sbjct: 129 FCDSYGLVCNKPTV 142


>gi|51036594 potassium channel tetramerisation domain containing 11
           [Homo sapiens]
          Length = 232

 Score = 73.9 bits (180), Expect = 1e-13
 Identities = 41/75 (54%), Positives = 48/75 (64%), Gaps = 4/75 (5%)

Query: 37  MLGAMF--GGDFPTARDPQG--NYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKE 92
           MLGAMF  G   P   + QG  +YFIDRDG  FR++LNFLR   L LP  + E  LLR E
Sbjct: 1   MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAE 60

Query: 93  ADFYQIEPLIQCLND 107
           ADFYQI PL+  L +
Sbjct: 61  ADFYQIRPLLDALRE 75


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 43/92 (46%), Positives = 53/92 (57%), Gaps = 2/92 (2%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           V LNVGG  ++TS  TL   PDS   ++  G   T RD  G  FIDRD   F  +LNFLR
Sbjct: 20  VQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLR 79

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105
           T E  L L     ++LR EA+FY I PL++ L
Sbjct: 80  TKE--LDLRGVSINVLRHEAEFYGITPLVRRL 109


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 49/130 (37%), Positives = 66/130 (50%), Gaps = 6/130 (4%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           V LNVGG LY T++  LTR+ D+ML AMF G      D +G   IDR G  F  +LN+LR
Sbjct: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLI----QCLNDPKPLY-PMDTFEEVVELSSTRK 128
              +TLP + +E   L  EA +Y I+ L+      L D K  Y P+     +  L    +
Sbjct: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEER 148

Query: 129 LSKYSNPVAV 138
           L + S    V
Sbjct: 149 LIESSTKPVV 158


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 41/92 (44%), Positives = 52/92 (56%), Gaps = 2/92 (2%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           + LNVGG  ++TS  TLT  PDS   ++  G   T +D  G  FIDRD  +F  +LNFLR
Sbjct: 21  IHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLR 80

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105
           T EL  P       LL  EA FY + PL++ L
Sbjct: 81  TKELD-PRGVHGSSLLH-EAQFYGLTPLVRRL 110


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 68.6 bits (166), Expect = 5e-12
 Identities = 46/129 (35%), Positives = 64/129 (49%), Gaps = 5/129 (3%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           V LNVGG LY T++ TLT+  D+ML AMF G      D +G   IDR G  F  +LN+LR
Sbjct: 34  VKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQ----CLNDPKPLYPMDTFEEVVELSSTRKL 129
              + LP   +E + L  EA +Y ++ L++     L +     P      +      +KL
Sbjct: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKL 152

Query: 130 SKYSNPVAV 138
              SN  AV
Sbjct: 153 IATSNKPAV 161


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 44/105 (41%), Positives = 57/105 (54%), Gaps = 6/105 (5%)

Query: 4   GDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGD-FPTARDPQGNYFIDRDG 62
           G WG      V LNVGG ++ T+  TL R   S L  +  G+   + RD  G Y IDRD 
Sbjct: 27  GGWGKW----VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDP 82

Query: 63  PLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLND 107
             F  +LNFLR  +L L  D  E  +L +EA+FY I PLI+ + D
Sbjct: 83  TYFGPILNFLRHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKD 126


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 51/142 (35%), Positives = 65/142 (45%), Gaps = 23/142 (16%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           V LNVGG L+ T+L TLT   D+ML AMF G      D  G   IDR G  F  +LN+LR
Sbjct: 43  VKLNVGGSLHYTTLRTLTGQ-DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLR 101

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLN----------DPKPLYPM--------- 114
              + LP   +E   L  EA +Y ++ LI+              P  L PM         
Sbjct: 102 DGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQ 161

Query: 115 ---DTFEEVVELSSTRKLSKYS 133
               T + VV+L   R  +KYS
Sbjct: 162 LLASTSKPVVKLLHNRSNNKYS 183


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 39/96 (40%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGD--FPTARDPQGNYFIDRDGPLFRYVLNF 71
           V LNVGG  + T+  TL R P S L  +   D    + +D  G Y IDRD   F  VLN+
Sbjct: 46  VRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNY 105

Query: 72  LRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLND 107
           LR  +L +  D  E  +L +EA+FY I  LI+ + D
Sbjct: 106 LRHGKLVINKDLAEEGVL-EEAEFYNITSLIKLVKD 140


>gi|155369221 potassium channel tetramerisation domain containing 19
           [Homo sapiens]
          Length = 926

 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 37/103 (35%), Positives = 53/103 (51%), Gaps = 24/103 (23%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDR--------DGPLF 65
           + + VG H Y T+L TL +YP+ +             +PQ  Y+I          DG +F
Sbjct: 398 IKVYVGSHWYATTLQTLLKYPELL------------SNPQRVYWITYGQTLLIHGDGQMF 445

Query: 66  RYVLNFLRTSELTLPLDFKEFDLLRKEADFYQI----EPLIQC 104
           R++LNFLR  +L LP +FKE+ L  +E + Y I    E L QC
Sbjct: 446 RHILNFLRLGKLFLPSEFKEWPLFCQEVEEYHIPSLSEALAQC 488



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 34/93 (36%), Positives = 54/93 (58%), Gaps = 4/93 (4%)

Query: 17  NVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSE 76
           NVGG  ++   + L+++PDS+L         T+ + Q   FIDRDG  FR+V  +L TS+
Sbjct: 18  NVGGWHFSVPRSKLSQFPDSLLWKEASA--LTSSESQ-RLFIDRDGSTFRHVHYYLYTSK 74

Query: 77  LTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPK 109
           L+      E +LL ++A   Q+ PL+Q L++ K
Sbjct: 75  LSFS-SCAELNLLYEQALGLQLMPLLQTLDNLK 106



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 9/103 (8%)

Query: 22  LYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPL 81
           LYT +L  L +YPDS LG +      +  D     +I  +G LF++V N+L T  L L  
Sbjct: 286 LYTMALGLLVKYPDSALGQL---RIESTLD-GSRLYITGNGVLFQHVKNWLGTCRLPLTE 341

Query: 82  DFKEFDLL-----RKEADFYQIEPLIQCLNDPKPLYPMDTFEE 119
              E   L     +++  +  I+  ++   +P+ L PMD   E
Sbjct: 342 TISEVYELCAFLDKRDITYEPIKVALKTHLEPRTLAPMDVLNE 384



 Score = 36.2 bits (82), Expect = 0.025
 Identities = 14/41 (34%), Positives = 26/41 (63%)

Query: 65  FRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105
           FR+++NFLR+ ++ LP +F   D+L  E +  +I  L + +
Sbjct: 211 FRFIVNFLRSQKILLPDNFSNIDVLEAEVEILEIPALTEAV 251


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 39/98 (39%), Positives = 57/98 (58%), Gaps = 4/98 (4%)

Query: 11  TDPVTLNVGGHLYTTSLTTL-TRYPDSMLGAMF--GGDFPTARDPQGNYFIDRDGPLFRY 67
           TD +TLNVGG  +TT+ +TL  + PDSML  MF   G +   +D +G + IDR    F  
Sbjct: 88  TDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEP 147

Query: 68  VLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105
           +LN+LR  +L +        +L +EA F+ I+ LI+ L
Sbjct: 148 ILNYLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHL 184


>gi|27436981 potassium voltage-gated channel, Shal-related
           subfamily, member 1 [Homo sapiens]
          Length = 647

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 36/89 (40%), Positives = 47/89 (52%), Gaps = 7/89 (7%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           + +NV G  + T   TL RYPD++LG+     F  A    G YF DRD  +FR+VLNF R
Sbjct: 42  LVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDA--DSGEYFFDRDPDMFRHVLNFYR 99

Query: 74  TSELTLPLD--FKEFDLLRKEADFYQIEP 100
           T  L  P     + FD   +E  FY + P
Sbjct: 100 TGRLHCPRQECIQAFD---EELAFYGLVP 125


>gi|27436984 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 1 [Homo sapiens]
          Length = 655

 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 3/89 (3%)

Query: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73
           + LNV G  + T  TTL RYPD++LG+     F    +    YF DRD  +FR VLNF R
Sbjct: 42  IVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFF--FNEDTKEYFFDRDPEVFRCVLNFYR 99

Query: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLI 102
           T +L  P  ++       E  FY I P I
Sbjct: 100 TGKLHYP-RYECISAYDDELAFYGILPEI 127


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,852,066
Number of Sequences: 37866
Number of extensions: 369572
Number of successful extensions: 818
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 723
Number of HSP's gapped (non-prelim): 73
length of query: 237
length of database: 18,247,518
effective HSP length: 99
effective length of query: 138
effective length of database: 14,498,784
effective search space: 2000832192
effective search space used: 2000832192
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.