Guide to the Human Genome
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Search of human proteins with 189409150

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189409150 chromatin modifying protein 5 [Homo sapiens]
         (219 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189409150 chromatin modifying protein 5 [Homo sapiens]             429   e-121
gi|40548422 chromatin modifying protein 4A [Homo sapiens]              78   5e-15
gi|28827795 chromatin modifying protein 4B [Homo sapiens]              72   5e-13
gi|22748643 chromatin modifying protein 4C [Homo sapiens]              60   1e-09
gi|38372933 chromatin modifying protein 2A [Homo sapiens]              54   1e-07
gi|7656922 chromatin modifying protein 2A [Homo sapiens]               54   1e-07
gi|22748641 CHMP family, member 7 [Homo sapiens]                       51   7e-07
gi|51317366 myosin XVIIIB [Homo sapiens]                               43   2e-04
gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens]        43   2e-04
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         42   3e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          41   7e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          41   7e-04
gi|239754976 PREDICTED: IQ motif and ankyrin repeat domain-conta...    41   0.001
gi|239743649 PREDICTED: IQ motif and ankyrin repeat domain-conta...    41   0.001
gi|122891870 melanoma inhibitory activity family, member 3 [Homo...    41   0.001
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    40   0.001
gi|110347443 TATA element modulatory factor 1 [Homo sapiens]           40   0.002
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    40   0.002
gi|21735548 centrosomal protein 2 [Homo sapiens]                       39   0.003
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          39   0.003
gi|153945715 myosin VC [Homo sapiens]                                  39   0.005
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    38   0.006
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            38   0.006
gi|163644316 hypothetical protein LOC23255 [Homo sapiens]              38   0.006
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    38   0.008
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]    38   0.008
gi|96975038 coiled-coil domain containing 100 [Homo sapiens]           37   0.010
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         37   0.013
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         37   0.013
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    37   0.013

>gi|189409150 chromatin modifying protein 5 [Homo sapiens]
          Length = 219

 Score =  429 bits (1103), Expect = e-121
 Identities = 219/219 (100%), Positives = 219/219 (100%)

Query: 1   MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
           MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
Sbjct: 1   MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60

Query: 61  VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120
           VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
Sbjct: 61  VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120

Query: 121 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS 180
           KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS
Sbjct: 121 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS 180

Query: 181 SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS 219
           SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS
Sbjct: 181 SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS 219


>gi|40548422 chromatin modifying protein 4A [Homo sapiens]
          Length = 265

 Score = 78.2 bits (191), Expect = 5e-15
 Identities = 55/182 (30%), Positives = 99/182 (54%), Gaps = 13/182 (7%)

Query: 1   MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
           + RLFGK K K   P+  + I  +    + + KK   L+    K + +++  ++   KN 
Sbjct: 47  LGRLFGKGK-KEKGPTPEEAIQKLKETEKILIKKQEFLEQ---KIQQELQTAKKYGTKN- 101

Query: 61  VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDA---MKLGVKEMK 117
            K+ AL+ L++K+ +EQQ   LAQ    +    +  +++++  T  +    M+L  + MK
Sbjct: 102 -KRAALQALRRKKRFEQQ---LAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMK 157

Query: 118 KAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYG-TPELDEDDLEAELDALGDELLA 176
           KAY+ + ID++++L   + +  E A +I +A+SR  G   ++DED+L  EL+ L  E LA
Sbjct: 158 KAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELA 217

Query: 177 DE 178
            E
Sbjct: 218 QE 219


>gi|28827795 chromatin modifying protein 4B [Homo sapiens]
          Length = 224

 Score = 71.6 bits (174), Expect = 5e-13
 Identities = 65/217 (29%), Positives = 101/217 (46%), Gaps = 29/217 (13%)

Query: 6   GKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKA 65
           GKA    P P   + I  +    E + KK   L+    K + ++   ++   KN  K+ A
Sbjct: 13  GKAGKGGPTPQ--EAIQRLRDTEEMLSKKQEFLEK---KIEQELTAAKKHGTKN--KRAA 65

Query: 66  LRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMK---LGVKEMKKAYKQ 122
           L+ LK+K+ YE+Q   LAQ    +    +  ++L++  T  + +K      K MK A+  
Sbjct: 66  LQALKRKKRYEKQ---LAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDN 122

Query: 123 VKIDQIEDLQDQLEDMMEDANEIQEALSRSYG-TPELDEDDLEAELDALGDELLADEDSS 181
           + ID++++L   + D  E A EI  A+S+  G   E DED+L AEL+ L  E L   D +
Sbjct: 123 MDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEEL---DKN 179

Query: 182 YLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPA 218
            L+ +      PE VP          V    LP  PA
Sbjct: 180 LLEISG-----PETVPLPN-------VPSIALPSKPA 204


>gi|22748643 chromatin modifying protein 4C [Homo sapiens]
          Length = 233

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 46/174 (26%), Positives = 90/174 (51%), Gaps = 13/174 (7%)

Query: 6   GKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKA 65
           G +K +A P S  + +  +    E + KK   L+  + +   +I   ++   +N  K+ A
Sbjct: 12  GSSKSRAAP-SPQEALVRLRETEEMLGKKQEYLENRIQR---EIALAKKHGTQN--KRAA 65

Query: 66  LRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMK---LGVKEMKKAYKQ 122
           L+ LK+K+ +E+Q   L Q    +    +  ++L+++ T  + ++      K MK  ++ 
Sbjct: 66  LQALKRKKRFEKQ---LTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHEN 122

Query: 123 VKIDQIEDLQDQLEDMMEDANEIQEALSRSYG-TPELDEDDLEAELDALGDELL 175
           + +++I+DL  ++ +  + A EI EA S+  G   + DED+L AEL+ L  E L
Sbjct: 123 MDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEEL 176


>gi|38372933 chromatin modifying protein 2A [Homo sapiens]
          Length = 222

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 46/191 (24%), Positives = 88/191 (46%), Gaps = 7/191 (3%)

Query: 1   MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
           M+ LFG+ K   P   L      ++     +D++  +L+ +  K    IKKM +    + 
Sbjct: 1   MDLLFGRRK--TPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA 58

Query: 61  VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120
           V+  A  +++ +R   +          N++  +  IQ+LK   +   AMK   K M    
Sbjct: 59  VRIMAKDLVRTRRYVRK----FVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMN 114

Query: 121 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS 180
           +Q+K+ QI+ +  + E   E  +  +E ++ +      DE+D E E DA+  ++L +   
Sbjct: 115 RQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEED-EEESDAVVSQVLDELGL 173

Query: 181 SYLDEAASAPA 191
           S  DE ++ P+
Sbjct: 174 SLTDELSNLPS 184


>gi|7656922 chromatin modifying protein 2A [Homo sapiens]
          Length = 222

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 46/191 (24%), Positives = 88/191 (46%), Gaps = 7/191 (3%)

Query: 1   MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
           M+ LFG+ K   P   L      ++     +D++  +L+ +  K    IKKM +    + 
Sbjct: 1   MDLLFGRRK--TPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA 58

Query: 61  VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY 120
           V+  A  +++ +R   +          N++  +  IQ+LK   +   AMK   K M    
Sbjct: 59  VRIMAKDLVRTRRYVRK----FVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMN 114

Query: 121 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS 180
           +Q+K+ QI+ +  + E   E  +  +E ++ +      DE+D E E DA+  ++L +   
Sbjct: 115 RQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEED-EEESDAVVSQVLDELGL 173

Query: 181 SYLDEAASAPA 191
           S  DE ++ P+
Sbjct: 174 SLTDELSNLPS 184


>gi|22748641 CHMP family, member 7 [Homo sapiens]
          Length = 453

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 36/142 (25%), Positives = 73/142 (51%), Gaps = 7/142 (4%)

Query: 31  IDKKISRLDAELVKYKDQIKKM-REGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNM 89
           + +K+  L  E  + K++ ++  R G      KQ ALR LK K+  E++ + L  +   +
Sbjct: 251 LSRKVESLSQEAERCKEEARRACRAGK-----KQLALRSLKAKQRTEKRIEALHAKLDTV 305

Query: 90  EQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEAL 149
           +     I + +  +   +A + GV  +K + K V +++ E L DQ++++ +  +E+ + L
Sbjct: 306 QGILDRIYASQTDQMVFNAYQAGVGALKLSMKDVTVEKAESLVDQIQELCDTQDEVSQTL 365

Query: 150 SRSYGTP-ELDEDDLEAELDAL 170
           +       + D ++LE ELD L
Sbjct: 366 AGGVTNGLDFDSEELEKELDIL 387


>gi|51317366 myosin XVIIIB [Homo sapiens]
          Length = 2567

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 31/157 (19%), Positives = 82/157 (52%), Gaps = 11/157 (7%)

Query: 21   IGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRD 80
            +G +  + +  +++ S+L  ++   +D  +++   P+   + +  +  LK+ R+++ +  
Sbjct: 1641 LGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPS---LGENCVAGLKE-RLWKLESS 1696

Query: 81   NLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMME 140
             L QQ    +Q N TI+ L+  +      +L ++ MK+ +++ + DQ E+L+D  +   +
Sbjct: 1697 ALEQQKIQSQQEN-TIKQLEQLR---QRFELEIERMKQMHQKDREDQEEELEDVRQSCQK 1752

Query: 141  DANEIQEALSRSYGTPEL---DEDDLEAELDALGDEL 174
              ++++  L + Y   ++   ++ DLE  +  L D++
Sbjct: 1753 RLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQI 1789



 Score = 33.1 bits (74), Expect = 0.19
 Identities = 30/136 (22%), Positives = 63/136 (46%), Gaps = 15/136 (11%)

Query: 21   IGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRD 80
            +GT++    S+ K+      EL K   Q+++      + +  QK L           + +
Sbjct: 1818 LGTMEDGKTSVSKE------ELEKVHSQLEQSEAKCEEALKTQKVLTA--DLESMHSELE 1869

Query: 81   NLAQQSFNMEQANYTIQSLK-DTKTTVDAMKLGVKEMKKAYKQV------KIDQIEDLQD 133
            N+ +    +++  Y +Q  K D    +D  +  + E+ + +K +       I QI++LQ 
Sbjct: 1870 NMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQL 1929

Query: 134  QLEDMMEDANEIQEAL 149
            QLE+  ++ +++QE L
Sbjct: 1930 QLEEAKKEKHKLQEQL 1945


>gi|7706353 vacuolar protein sorting 24 isoform 1 [Homo sapiens]
          Length = 222

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 40/196 (20%), Positives = 84/196 (42%), Gaps = 7/196 (3%)

Query: 4   LFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQ 63
           LFGK + K P   + +    +      +D++I  +  E    ++++K+  +  AK   K 
Sbjct: 3   LFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQRE----EEKVKRSVKDAAKKGQKD 58

Query: 64  KALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQV 123
             + + K+     +    L     +M      +++         +++   + MK     V
Sbjct: 59  VCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLV 118

Query: 124 KIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYL 183
           KI +I+    +L   M  A  I+E L  ++ + + D++++E E +   D +L +  +  L
Sbjct: 119 KIPEIQATMRELSKEMMKAGIIEEMLEDTFESMD-DQEEMEEEAEMEIDRILFEITAGAL 177

Query: 184 DEAAS--APAIPEGVP 197
            +A S    A+PE  P
Sbjct: 178 GKAPSKVTDALPEPEP 193


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 36/150 (24%), Positives = 71/150 (47%), Gaps = 12/150 (8%)

Query: 20  CIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLK-QKRMYEQQ 78
           C  T     ES  K  +  +   +++ +QI KM   P +  +K+K  +V++ +++  EQ+
Sbjct: 249 CPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQE 308

Query: 79  RDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKK---AYKQVKIDQIEDLQDQ- 134
              +AQ+   +E+         +    V+  + G +E K+    +   + +Q E+ Q Q 
Sbjct: 309 EGKVAQREEELEETG-------NQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQE 361

Query: 135 LEDMMEDANEIQEALSRSYGTPELDEDDLE 164
           +E  ME+  E++E+  +    PE   D LE
Sbjct: 362 MEVKMEEETEVRESEKQQDSQPEEVMDVLE 391


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 38/183 (20%)

Query: 34   KISRLDAELVKYKDQIKKMREGPAKNMVKQKA--LRVLKQKRMYEQQRDNLAQQSFNMEQ 91
            K  R   EL   + +I++ RE   K MV++K   L+ +KQ  +++Q+ +  AQ  F M Q
Sbjct: 3227 KQQRFAEELEWERQEIQRFRE-QEKIMVQKKLEELQSMKQHLLFQQEEERQAQ--FMMRQ 3283

Query: 92   ANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSR 151
                                       A +Q++++QI+ LQ QL   +E+  +I++    
Sbjct: 3284 ETL------------------------AQQQLQLEQIQQLQQQLHQQLEE-QKIRQIYQY 3318

Query: 152  SY-----GTPELDEDD--LEAELDAL-GDELLADEDSSYLDEAASAPAIPEGVPTDTKNK 203
            +Y      +P+   +   LE +  AL G +  A ED++    A  A  IP+     T   
Sbjct: 3319 NYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVAIEIPQSQGWYTVQS 3378

Query: 204  DGV 206
            DGV
Sbjct: 3379 DGV 3381



 Score = 32.0 bits (71), Expect = 0.42
 Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 26/205 (12%)

Query: 32   DKKISRLDAELVKYKDQIKKMREGPAKNMVK-----QKALRVLKQKRMYEQQRD------ 80
            +KK    + +L+  +++I+   + P     K     +K L   K     EQ+ D      
Sbjct: 1210 EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQV 1269

Query: 81   NLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGV-----KEMKKAYKQVKIDQIEDLQDQL 135
             +A++      A  T+Q  K  +T ++ +  G      KE  K  K +K +Q +      
Sbjct: 1270 QIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIK-EQPQPPCTAK 1328

Query: 136  EDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEG 195
             D +E   E  E         E D+ D  +       + L+D   S    ++S   IP  
Sbjct: 1329 PDQVEPGKEKTEK--------EDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380

Query: 196  VPTDTKN-KDGVLVDEFGLPQIPAS 219
            +PTD K+   G+  D F     P+S
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESSPSS 1405


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 38/183 (20%)

Query: 34   KISRLDAELVKYKDQIKKMREGPAKNMVKQKA--LRVLKQKRMYEQQRDNLAQQSFNMEQ 91
            K  R   EL   + +I++ RE   K MV++K   L+ +KQ  +++Q+ +  AQ  F M Q
Sbjct: 3227 KQQRFAEELEWERQEIQRFRE-QEKIMVQKKLEELQSMKQHLLFQQEEERQAQ--FMMRQ 3283

Query: 92   ANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSR 151
                                       A +Q++++QI+ LQ QL   +E+  +I++    
Sbjct: 3284 ETL------------------------AQQQLQLEQIQQLQQQLHQQLEE-QKIRQIYQY 3318

Query: 152  SY-----GTPELDEDD--LEAELDAL-GDELLADEDSSYLDEAASAPAIPEGVPTDTKNK 203
            +Y      +P+   +   LE +  AL G +  A ED++    A  A  IP+     T   
Sbjct: 3319 NYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVAIEIPQSQGWYTVQS 3378

Query: 204  DGV 206
            DGV
Sbjct: 3379 DGV 3381



 Score = 32.0 bits (71), Expect = 0.42
 Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 26/205 (12%)

Query: 32   DKKISRLDAELVKYKDQIKKMREGPAKNMVK-----QKALRVLKQKRMYEQQRD------ 80
            +KK    + +L+  +++I+   + P     K     +K L   K     EQ+ D      
Sbjct: 1210 EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQV 1269

Query: 81   NLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGV-----KEMKKAYKQVKIDQIEDLQDQL 135
             +A++      A  T+Q  K  +T ++ +  G      KE  K  K +K +Q +      
Sbjct: 1270 QIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIK-EQPQPPCTAK 1328

Query: 136  EDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEG 195
             D +E   E  E         E D+ D  +       + L+D   S    ++S   IP  
Sbjct: 1329 PDQVEPGKEKTEK--------EDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380

Query: 196  VPTDTKN-KDGVLVDEFGLPQIPAS 219
            +PTD K+   G+  D F     P+S
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESSPSS 1405


>gi|239754976 PREDICTED: IQ motif and ankyrin repeat
           domain-containing protein LOC642574 [Homo sapiens]
          Length = 484

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 32/176 (18%), Positives = 77/176 (43%), Gaps = 16/176 (9%)

Query: 35  ISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFN------ 88
           +  ++AE  +   + ++ +E  A+ M  +      +Q++ +++ +    + S        
Sbjct: 213 LQNMEAEQQRRAQEAQRHKEAEAERMTLKVQQLTREQQQCHKELQQAYCELSRRISEHDQ 272

Query: 89  -----MEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLED---MME 140
                M++   T+Q++KDT+  VD ++   ++ ++A    +++  E  Q+  E+   +  
Sbjct: 273 CEWRCMDKTKLTLQAIKDTEAQVDRLRQEAQKAEEALAMARLELREQTQEGEEEAPGLKC 332

Query: 141 DANEIQEALSRSYGTPELDEDDLEAELDALGD--ELLADEDSSYLDEAASAPAIPE 194
              E+ + L +  G     +      +D LG     L  +D++Y+D     P  PE
Sbjct: 333 QVTELHDVLMKDVGNRIRADGRWPLVIDPLGQAATFLRYQDTNYVDTVNPEPLRPE 388


>gi|239743649 PREDICTED: IQ motif and ankyrin repeat
           domain-containing protein LOC642574 [Homo sapiens]
          Length = 580

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 32/176 (18%), Positives = 77/176 (43%), Gaps = 16/176 (9%)

Query: 35  ISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFN------ 88
           +  ++AE  +   + ++ +E  A+ M  +      +Q++ +++ +    + S        
Sbjct: 309 LQNMEAEQQRRAQEAQRHKEAEAERMTLKVQQLTREQQQCHKELQQAYCELSRRISEHDQ 368

Query: 89  -----MEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLED---MME 140
                M++   T+Q++KDT+  VD ++   ++ ++A    +++  E  Q+  E+   +  
Sbjct: 369 CEWRCMDKTKLTLQAIKDTEAQVDRLRQEAQKAEEALAMARLELREQTQEGEEEAPGLKC 428

Query: 141 DANEIQEALSRSYGTPELDEDDLEAELDALGD--ELLADEDSSYLDEAASAPAIPE 194
              E+ + L +  G     +      +D LG     L  +D++Y+D     P  PE
Sbjct: 429 QVTELHDVLMKDVGNRIRADGRWPLVIDPLGQAATFLRYQDTNYVDTVNPEPLRPE 484


>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
            sapiens]
          Length = 1907

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 18/152 (11%)

Query: 38   LDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQ 97
            L  E +KYKD+IK + +         K LRV     M E +R+   +    + +   +I+
Sbjct: 1258 LSDEAIKYKDKIKTLEKNQEILDDTAKNLRV-----MLESEREQNVKNQDLISENKKSIE 1312

Query: 98   SLKDT----KTTVDAMKLGVKEMKKAYKQVKID---------QIEDLQDQLEDMMEDANE 144
             LKD      +    +++ + E K + ++VK +         +++  ++QL+  +ED ++
Sbjct: 1313 KLKDVISMNASEFSEVQIALNEAKLSEEKVKSECHRVQEENARLKKKKEQLQQEIEDWSK 1372

Query: 145  IQEALSRSYGTPELDEDDLEAELDALGDELLA 176
            +   LS    + E  + DLE  L    D + A
Sbjct: 1373 LHAELSEQIKSFEKSQKDLEVALTHKDDNINA 1404


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 54/212 (25%), Positives = 82/212 (38%), Gaps = 23/212 (10%)

Query: 7   KAKPKAPP------PSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKM---REGPA 57
           KA+ KAPP      P + +  G   S + S     S  D+E  K     KK    ++  A
Sbjct: 193 KAQTKAPPKPARAAPKIAN--GKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVA 250

Query: 58  KNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMK 117
           K  VK       K     +   D   +Q   M+       S+           LG +  K
Sbjct: 251 KAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK 310

Query: 118 KAY-KQVKIDQIEDLQDQLEDMMEDANE--IQEALSRSYGTPELDEDDLEAELDALGDEL 174
           KA  KQ  ++  ED  D+ +   E+  +   +  +S++   P   +   E+  D+     
Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDS----- 365

Query: 175 LADEDSSYLDEAASAPAIPEGVPTDTKNKDGV 206
            +D DSS  DEA S PA   G   ++ NK  V
Sbjct: 366 -SDSDSSEDDEAPSKPA---GTTKNSSNKPAV 393


>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
          Length = 1093

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 38/149 (25%), Positives = 71/149 (47%), Gaps = 23/149 (15%)

Query: 41  ELVKYKDQIKKMREGPAKNMVKQKA--LRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQS 98
           E +  K+ + K  E   + + K++A  L + K+K + E+  DNL  + F +++ + +I S
Sbjct: 439 EALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISS 498

Query: 99  LKD--TKTTVDAMK---LGVKEMKKAYKQVK---------------IDQIEDLQDQLEDM 138
           LKD  T+   +A K   L  KE   A K++K                D +++  +Q+  +
Sbjct: 499 LKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGL 558

Query: 139 MEDANEI-QEALSRSYGTPELDEDDLEAE 166
           ME+  ++ ++ L  S    +L   D E E
Sbjct: 559 MEEGEKLSKQQLHNSNIIKKLRAKDKENE 587



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 31/145 (21%), Positives = 69/145 (47%), Gaps = 7/145 (4%)

Query: 27  RAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQK----RMYEQQRDNL 82
           R    +KK+     E    K +IK ++E  A  +   +   +LK+K    R   ++ + L
Sbjct: 506 RIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKL 565

Query: 83  AQQSFNMEQANYTIQSL-KDTKTTVDAMKLGVKEMKKAYKQVK--IDQIEDLQDQLEDMM 139
           ++Q  +       +++  K+ +  V  +   VKE+++  + +K  +D  E+++ Q  + +
Sbjct: 566 SKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENI 625

Query: 140 EDANEIQEALSRSYGTPELDEDDLE 164
           +  N + E   +  G  ++D D+LE
Sbjct: 626 KKLNSMVERQEKDLGRLQVDMDELE 650



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 46/189 (24%), Positives = 81/189 (42%), Gaps = 25/189 (13%)

Query: 25  DSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQ 84
           ++    ++KK+  L+ EL      +K++ +G  + + KQ    + K   M E+Q  +L +
Sbjct: 587 ENMVAKLNKKVKELEEEL----QHLKQVLDGK-EEVEKQHRENIKKLNSMVERQEKDLGR 641

Query: 85  QSFNM---EQANYTIQSLKDT--KTTVDAMKLGV---KEMKKAYKQVKIDQIEDLQDQLE 136
              +M   E+ N +IQ+  D+  K   D  K       E ++A    ++   E+L   LE
Sbjct: 642 LQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALE 701

Query: 137 DMMEDANEIQEALSRSYGTPEL-----------DEDDLEAELDALGDELL-ADEDSSYLD 184
              E+A + QE L+   G   L            ED L  E+  L   L  A+  +  L 
Sbjct: 702 KAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELS 761

Query: 185 EAASAPAIP 193
           ++ S+   P
Sbjct: 762 QSVSSTTRP 770


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 28/113 (24%), Positives = 59/113 (52%), Gaps = 5/113 (4%)

Query: 43   VKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQR--DNLAQQSFN-MEQANYTIQSL 99
            + Y D  + +++  A+  +KQ+ +  L+QK + EQQ     +A  +   ME+        
Sbjct: 981  IDYGDLCEDLKDAQAEEEIKQE-MNTLQQK-LNEQQSVLQRIAAPNMKAMEKLESVRDKF 1038

Query: 100  KDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRS 152
            ++T    +A +   K+ K+A++Q+K ++ +      E +  + +EI +ALSR+
Sbjct: 1039 QETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRN 1091



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 23/165 (13%)

Query: 21  IGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRD 80
           +G +    + I+K+I   D+EL + + Q  K +E  +  + K +A               
Sbjct: 270 LGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEA--------------- 314

Query: 81  NLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMME 140
             A++S    Q +Y     K  K  +D ++  +  ++KA ++ +    E+ Q Q  D+  
Sbjct: 315 --AKKSLQNAQKHY-----KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTL 367

Query: 141 DANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDE 185
           + N++++   R           L  EL+    +  AD+D   L+E
Sbjct: 368 EENQVKK-YHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 35/169 (20%), Positives = 79/169 (46%), Gaps = 22/169 (13%)

Query: 21   IGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM-VKQKALRVLKQKRMYEQQR 79
            I  +  + E + + + R D EL+  K++I+ + +   +   + ++ L  +K   + E+ R
Sbjct: 1639 IEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLS-LRERGR 1697

Query: 80   DNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYK--QVKIDQIEDLQDQLED 137
            +   Q+    E+A       K  + +++ MKL +++ +K  +  Q  I ++++L+DQLE 
Sbjct: 1698 ELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQ 1757

Query: 138  MMEDANE------------------IQEALSRSYGTPELDEDDLEAELD 168
             ++  +                   +Q+ L  +    EL E  L+++LD
Sbjct: 1758 QLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLD 1806



 Score = 35.0 bits (79), Expect = 0.050
 Identities = 27/160 (16%), Positives = 73/160 (45%), Gaps = 3/160 (1%)

Query: 29   ESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFN 88
            + + K +  L+ E ++ + ++K+ +        +++  R   +  + + Q +   ++   
Sbjct: 871  QELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSL 930

Query: 89   MEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQ---VKIDQIEDLQDQLEDMMEDANEI 145
            +E    T + L D    ++ ++  +K  K   ++   +   Q+++ Q +L++      + 
Sbjct: 931  LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDD 990

Query: 146  QEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDE 185
              AL     +   D+ DL+ +++ L  +L+A +DS  L E
Sbjct: 991  LAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVE 1030



 Score = 35.0 bits (79), Expect = 0.050
 Identities = 34/153 (22%), Positives = 72/153 (47%), Gaps = 5/153 (3%)

Query: 25   DSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQ 84
            D   ES   ++  L  +LV  +    ++ E   K   +QK ++ L+ +R  E QR  L  
Sbjct: 1535 DQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQR--ETQRVALTH 1592

Query: 85   QSFNMEQANYTIQSLKDTKTTVDAMKLGV-KEMKKAYKQVKI--DQIEDLQDQLEDMMED 141
             + ++E+ +  +Q+       +++    + +E+++  ++VK   +QIE+LQ Q E + +D
Sbjct: 1593 LTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQD 1652

Query: 142  ANEIQEALSRSYGTPELDEDDLEAELDALGDEL 174
                 + L       ++ ED    +   L ++L
Sbjct: 1653 LERRDQELMLQKERIQVLEDQRTRQTKILEEDL 1685



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 23/147 (15%)

Query: 32  DKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQ 91
           ++ I+ L +     K ++  +R    K     +AL + K           L QQ   +E+
Sbjct: 574 EQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKV---------GLNQQLLQLEE 624

Query: 92  ANYTIQS-LKDTKTTVDAMKLGVKEMKK---------AYKQVKIDQIED----LQDQLED 137
            N ++ S ++  +   +A+++ + E +K          + + ++ + E+    LQ  L D
Sbjct: 625 ENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRD 684

Query: 138 MMEDANEIQEALSRSYGTPELDEDDLE 164
           + E+  EIQ+ LS S    E     LE
Sbjct: 685 IQEEKEEIQKKLSESRHQQEAATTQLE 711


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 34/149 (22%), Positives = 67/149 (44%), Gaps = 27/149 (18%)

Query: 27  RAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQS 86
           R + + +++   +AEL   +D +   +E   K+      L+ +KQ  +Y+  +D L +Q 
Sbjct: 442 RQQQLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQ--LYQASKDELERQK 499

Query: 87  FNMEQANYTI----QSLKDTKTT-------------VDAMKLGVKEMKKAYK-------Q 122
              +Q    +      LK+ K +              D +   + E+++ YK       Q
Sbjct: 500 HMYDQLEQDLLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQEKYKASQKEMGQ 559

Query: 123 VKIDQIEDLQDQLEDMMEDANEIQEALSR 151
           ++++Q E L+DQ   M E+  ++QE L R
Sbjct: 560 LQMEQCELLEDQ-RRMQEEQGQLQEELHR 587



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 35/157 (22%), Positives = 65/157 (41%), Gaps = 29/157 (18%)

Query: 25   DSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQ 84
            ++R ++ +K +++ +A  VK K   K   +    ++  +K+L V+   +  +++ D LA+
Sbjct: 977  EARGKNANKNMNK-NANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQRKLDGLAK 1035

Query: 85   QSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANE 144
            +    E                        EM++  KQVK +  E   D+L     D  E
Sbjct: 1036 EEEKKE------------------------EMEEEKKQVKEEAKEQCGDELVAEPADPEE 1071

Query: 145  IQEALSRSYGTPELDEDDLEAELDALGDELLADEDSS 181
             +    +     E +ED  E E +   +E   D DSS
Sbjct: 1072 AKSTEDQE----ENEEDKEEEEKEEDSEEEEDDADSS 1104


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 44/197 (22%), Positives = 83/197 (42%), Gaps = 34/197 (17%)

Query: 24   VDSRAESIDKKISRLDAELVKYKDQIKK-----MREGPAKNMVKQKALRVLKQKRMYEQQ 78
            ++++ E I  K+     EL +  D + K     +++   + M+ +K+  +  Q   YE+Q
Sbjct: 968  LETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQD--YEKQ 1025

Query: 79   RDNLAQQSFNMEQANYTIQSLKDTK-TTVDAMKLGVKEMKKAYKQV-------------K 124
              +L ++   ++     +Q L + +  T D +K  V  + K  K +             K
Sbjct: 1026 IQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQK 1085

Query: 125  IDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLD 184
            ID  + +Q Q  +M E  +EI + L  SY     D +D+ + L          ED  +L+
Sbjct: 1086 IDVEKHVQSQKREMREKMSEITKQLLESY-----DIEDVRSRLSV--------EDLEHLN 1132

Query: 185  EAASAPAIPEGVPTDTK 201
            E        EG+   T+
Sbjct: 1133 EDGELWFAYEGLKKATR 1149



 Score = 33.1 bits (74), Expect = 0.19
 Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 15/143 (10%)

Query: 29   ESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFN 88
            ESI  +++RL +E +   D  +++ E     + KQK    ++     E+ +  L + S  
Sbjct: 1195 ESIRHEVTRLTSENMMIPDFKQQISE-----LEKQKQDLEIRLNEQAEKMKGKLEELS-- 1247

Query: 89   MEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQ---DQLEDMMEDANEI 145
                N   +S ++  T   A++    E+    K+  ID+I+++Q   D L+   E  +E+
Sbjct: 1248 ----NQLHRSQEEEGTQRKALE-AQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEV 1302

Query: 146  QEALSRSYGTPELDEDDLEAELD 168
            +    +      L+  DLE ELD
Sbjct: 1303 KCNFRQEASRLTLENRDLEEELD 1325


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 37/176 (21%), Positives = 75/176 (42%), Gaps = 8/176 (4%)

Query: 1   MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM 60
           M+R F  A   A   +L   I   DS+  S+++ +  L+ E+   K       E   + M
Sbjct: 364 MHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEM 423

Query: 61  VKQKALRVLKQ--KRMYEQQRDNLAQQSFNMEQANYTIQSL----KDTKTTVDAMK--LG 112
            + +  R   +  K    Q +  L+++   +      +++L     D+K  ++ +K  L 
Sbjct: 424 KQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 483

Query: 113 VKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELD 168
            KE + A  Q ++D +    ++ E M+    +  + ++   GT   +  DL+  LD
Sbjct: 484 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLD 539



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 23/102 (22%), Positives = 49/102 (48%), Gaps = 12/102 (11%)

Query: 61  VKQKALRVLKQK--RMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKK 118
           VK++ + VL++K   + EQ RD   Q S   E+         +T T +  ++  + E ++
Sbjct: 540 VKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKER 599

Query: 119 AYKQVKI----------DQIEDLQDQLEDMMEDANEIQEALS 150
             +++K           ++I++ +  L+D+ E  + +Q  LS
Sbjct: 600 TIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLS 641



 Score = 29.6 bits (65), Expect = 2.1
 Identities = 29/174 (16%), Positives = 80/174 (45%), Gaps = 17/174 (9%)

Query: 25  DSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVK-QKALRVLKQKRMYEQQRDNLA 83
           DSR ++++  + +   E +K + Q+KK  E   +     + + R+   +R   + +D  +
Sbjct: 665 DSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESS 724

Query: 84  QQSFNMEQANYTIQSLKDTKTTVD----AMKLGVKEMKKAYKQVK----------IDQIE 129
           +    +++    ++ +++ K   D     ++  VK+  K    +K             +E
Sbjct: 725 KAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLE 784

Query: 130 DLQDQLEDMMEDANEIQEALSRSYGTPELDEDDL--EAELDALGDELLADEDSS 181
           + + + +++ + + ++Q++L +     E  E+ L    ++ A  + +LA E+S+
Sbjct: 785 EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESA 838


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 40/183 (21%), Positives = 82/183 (44%), Gaps = 11/183 (6%)

Query: 29  ESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFN 88
           E + ++  ++  +  K  +Q +KM+E   K M +Q+     ++++M+EQQR  L +Q   
Sbjct: 26  EKMQEQEEKMREQEEKMWEQEEKMQEQEEK-MWEQEEKMWEQEEKMWEQQR--LPEQKEK 82

Query: 89  M----EQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANE 144
           M    E+     + +++ K      K+  +E KK  ++   +Q E +Q+Q E M E   +
Sbjct: 83  MWEQDERLREKEERMREQKMWQQVEKM--REKKKTQEEKMQEQEEKMQEQEEMMWEQEEK 140

Query: 145 IQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKD 204
           +QE   + +   E   +  E   +   +E +  ++    D   +     EG P D     
Sbjct: 141 MQEQEEKMWEQEEKMREQEEKMREQ--EEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQ 198

Query: 205 GVL 207
            ++
Sbjct: 199 EIM 201


>gi|163644316 hypothetical protein LOC23255 [Homo sapiens]
          Length = 1586

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 39/168 (23%), Positives = 77/168 (45%), Gaps = 11/168 (6%)

Query: 27  RAESIDKKIS---RLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMY-EQQRDNL 82
           +AE    K++   ++D EL++  +Q  K+ +  +  +  +  L+ +++KR   E + + L
Sbjct: 39  KAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHE--LKTVEEKRAKAEDENETL 96

Query: 83  AQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDA 142
            QQ   +E +   +Q+  +        +   +EM K  K    D   DL+ QL+   E+A
Sbjct: 97  RQQMIEVEISKQALQNELERLKESSLKRRSTREMYKEKKTFNQDDSADLRCQLQFAKEEA 156

Query: 143 NEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAP 190
             +++ +++       ++D+LE EL      L  D DS      A  P
Sbjct: 157 FLMRKKMAKL----GREKDELEQELQKY-KSLYGDVDSPLPTGEAGGP 199


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 27/142 (19%), Positives = 64/142 (45%), Gaps = 1/142 (0%)

Query: 43   VKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDT 102
            +K  +  KK  +   +  +KQ+ ++ LK++   ++  + + Q     +  N   + ++D 
Sbjct: 1278 IKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM 1337

Query: 103  KTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDD 162
            + T++  +    E  +   + K++++E L  +LE   E  N+++   ++       +  D
Sbjct: 1338 RMTLEEQEQTQVEQDQVL-EAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTD 1396

Query: 163  LEAELDALGDELLADEDSSYLD 184
            +  +L  L DEL   E     D
Sbjct: 1397 VLGKLTNLQDELQESEQKYNAD 1418



 Score = 34.7 bits (78), Expect = 0.065
 Identities = 22/101 (21%), Positives = 52/101 (51%), Gaps = 6/101 (5%)

Query: 29   ESIDKKISRLDAELVKYKDQIKKMREGPAKN---MVKQKALRVLKQKRMYEQQRDNLAQQ 85
            E ++++I +L AE+  YKD+  +++E   KN   ++K+K   + + K   +++   L  Q
Sbjct: 1039 EELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQ 1098

Query: 86   SFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKID 126
              ++ +     ++L +    V   K  +KE++   +  K++
Sbjct: 1099 IQHVVEGK---RALSELTQGVTCYKAKIKELETILETQKVE 1136



 Score = 29.3 bits (64), Expect = 2.7
 Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 104  TTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDL 163
            ++++A+    KE+ KA  + K  QIE+L+ Q+E +  +    ++  +R       ++DDL
Sbjct: 1015 SSIEAIWEECKEIVKASSK-KSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDL 1073

Query: 164  EAELDALGDEL 174
              E + L  +L
Sbjct: 1074 LKEKETLIQQL 1084


>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
          Length = 1498

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 36/156 (23%), Positives = 76/156 (48%), Gaps = 12/156 (7%)

Query: 30  SIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKA--LRVLKQKRMYEQQRDNLAQQSF 87
           S+ ++++      +K K +I    +G   +M+ Q+A  +++ + K M E+   +L ++  
Sbjct: 619 SLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEE---DLQRRLE 675

Query: 88  NMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQE 147
             E     +Q + D+  +++     ++++K    Q +  Q+E LQ +  D+M+     QE
Sbjct: 676 EFEGERERLQRMADSAASLEQQ---LEQVKLTLLQ-RDQQLEALQQEHLDLMKQLTLTQE 731

Query: 148 AL---SRSYGTPELDEDDLEAELDALGDELLADEDS 180
           AL    +S    +   D+L+A L  L  E  + ED+
Sbjct: 732 ALQSREQSLDALQTHYDELQARLGELQGEAASREDT 767


>gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
          Length = 986

 Score = 37.4 bits (85), Expect = 0.010
 Identities = 42/195 (21%), Positives = 82/195 (42%), Gaps = 19/195 (9%)

Query: 9   KPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRV 68
           KP + PP+   C   + +      +  + L+ E+ K      +M+E   +N +KQK L  
Sbjct: 628 KPSSLPPA--PCPSEIQTEPRETLEYKAALELEMWK------EMQEDIFENQLKQKELAH 679

Query: 69  LKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVD---------AMKLGVKEMKKA 119
           ++      ++RD   +     + A YTI   K  KT +D         +++  ++  KK 
Sbjct: 680 MQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKE 739

Query: 120 YKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGD--ELLAD 177
            +  +   +++LQD +    ED     E         E D+  L+ +L+   +  ++L  
Sbjct: 740 LQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEK 799

Query: 178 EDSSYLDEAASAPAI 192
           E   + D+  + P I
Sbjct: 800 EFQQFKDQQNNKPEI 814


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 37.0 bits (84), Expect = 0.013
 Identities = 37/164 (22%), Positives = 77/164 (46%), Gaps = 20/164 (12%)

Query: 24  VDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRV-LKQKRMYEQQRDNL 82
           V+S++E +  +I+ L  E+   + + K+  +G  +  V++  L+  L +K+M E++ D  
Sbjct: 710 VNSKSEEMTLQINELQKEIEILRQEEKE--KGTLEQEVQELQLKTELLEKQMKEKEND-- 765

Query: 83  AQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKID-------------QIE 129
            Q+ F   +A  +I  LKD K T++ M      + +  + + +D             +IE
Sbjct: 766 LQEKFAQLEAENSI--LKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIE 823

Query: 130 DLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDE 173
            L ++ ED+ +   ++ E + +   T    E + E     L +E
Sbjct: 824 ILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEE 867



 Score = 35.8 bits (81), Expect = 0.029
 Identities = 36/166 (21%), Positives = 75/166 (45%), Gaps = 22/166 (13%)

Query: 19   DCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREG--PAKNM----VKQKALRVLKQK 72
            +C+   D R  S+  +I  L A++   K  +K+ +E   P++ +    ++QK  ++L+ +
Sbjct: 3080 ECLQKADRR--SLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQ 3137

Query: 73   RMYEQQRDNLAQQSFNMEQANYTIQSLK--------DTKTTVDAMKLGVKEMKKAYKQVK 124
                  +D   +    +      +  LK        + +TT+ A    +KE++    +VK
Sbjct: 3138 VELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVK 3197

Query: 125  --IDQIEDLQDQLEDMMEDANEIQEALSRSYG----TPELDEDDLE 164
               D++  L D L    + + E+Q AL +       + E D+++LE
Sbjct: 3198 DKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELE 3243



 Score = 31.6 bits (70), Expect = 0.55
 Identities = 30/169 (17%), Positives = 69/169 (40%), Gaps = 28/169 (16%)

Query: 18   TDCIGTVDSRAESIDKKISRLDAE---------LVKYKDQIKKMREGPAKNMVKQKALRV 68
            TD I  ++        ++  L+AE         L+  + +  K   GP +  + Q+  ++
Sbjct: 1942 TDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKL 2001

Query: 69   LKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY---KQVKI 125
            +K+K   + Q + +                  D +  V A+++ V+E    +   +Q K 
Sbjct: 2002 MKEKLEVQCQAEKVRD----------------DLQKQVKALEIDVEEQVSRFIELEQEKN 2045

Query: 126  DQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDEL 174
             ++ DL+ Q + + +   ++++ L       E + D  + E+  L  +L
Sbjct: 2046 TELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQL 2094



 Score = 31.6 bits (70), Expect = 0.55
 Identities = 32/161 (19%), Positives = 74/161 (45%), Gaps = 20/161 (12%)

Query: 34   KISRLDAELVKYKDQIKKM----REGPAKNMVKQKAL-----RVLKQKRMYEQQRDNLA- 83
            ++  L+ E   +KD ++K+    +E  A +   Q  L     +++++K +   Q +    
Sbjct: 2243 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVT 2302

Query: 84   --QQSFNMEQANYTIQS----LKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLED 137
              QQ   +   N  I+     ++D +T ++ +       ++  K+ + ++IE L + +E 
Sbjct: 2303 KLQQQLKITTDNKVIEEKNELIRDLETQIECLMSD----QECVKRNREEEIEQLNEVIEK 2358

Query: 138  MMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADE 178
            + ++   I +  S +  +   + D L+ +LD +  E LA E
Sbjct: 2359 LQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALE 2399



 Score = 30.8 bits (68), Expect = 0.94
 Identities = 32/174 (18%), Positives = 83/174 (47%), Gaps = 24/174 (13%)

Query: 19  DCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQ 78
           D I  ++     ++ K+   +++  K K+++  + E   +    Q+ L  L ++  + ++
Sbjct: 486 DQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILE---EKCALQRQLEDLVEELSFSRE 542

Query: 79  -----RDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQD 133
                R  +A+Q   + +A+ ++ +++D K  + +     KE++  ++     ++ + + 
Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEA----EVTNYKI 598

Query: 134 QLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELL--ADEDSSYLDE 185
           +LE + ++ N + + ++ S           EAEL+ L  +LL   +E+ S L E
Sbjct: 599 KLEMLEKEKNAVLDRMAESQ----------EAELERLRTQLLFSHEEELSKLKE 642



 Score = 28.5 bits (62), Expect = 4.7
 Identities = 30/137 (21%), Positives = 60/137 (43%), Gaps = 7/137 (5%)

Query: 32  DKKISRLDAELVKYKDQIKKMREGPAKNMVKQK-ALRVLKQKR--MYEQQRDNLAQQSFN 88
           DK +  L  ++V+   +IK M+     +  K++ +   +KQ    + E Q+ N     F 
Sbjct: 356 DKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFE 415

Query: 89  MEQANYTIQSLKDTKTTVDAMKLGVKEMK-KAYKQVKIDQIEDLQDQLEDMMEDANEIQE 147
            +      Q   +T+  ++ ++  + EM  +   Q+K + I     Q+E+M        E
Sbjct: 416 TDIVQRMEQ---ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEME 472

Query: 148 ALSRSYGTPELDEDDLE 164
              RSY    ++ED ++
Sbjct: 473 NALRSYSNITVNEDQIK 489


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 37.0 bits (84), Expect = 0.013
 Identities = 37/164 (22%), Positives = 77/164 (46%), Gaps = 20/164 (12%)

Query: 24  VDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRV-LKQKRMYEQQRDNL 82
           V+S++E +  +I+ L  E+   + + K+  +G  +  V++  L+  L +K+M E++ D  
Sbjct: 710 VNSKSEEMTLQINELQKEIEILRQEEKE--KGTLEQEVQELQLKTELLEKQMKEKEND-- 765

Query: 83  AQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKID-------------QIE 129
            Q+ F   +A  +I  LKD K T++ M      + +  + + +D             +IE
Sbjct: 766 LQEKFAQLEAENSI--LKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIE 823

Query: 130 DLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDE 173
            L ++ ED+ +   ++ E + +   T    E + E     L +E
Sbjct: 824 ILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEE 867



 Score = 35.8 bits (81), Expect = 0.029
 Identities = 36/166 (21%), Positives = 75/166 (45%), Gaps = 22/166 (13%)

Query: 19   DCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREG--PAKNM----VKQKALRVLKQK 72
            +C+   D R  S+  +I  L A++   K  +K+ +E   P++ +    ++QK  ++L+ +
Sbjct: 3072 ECLQKADRR--SLLSEIQALHAQMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQ 3129

Query: 73   RMYEQQRDNLAQQSFNMEQANYTIQSLK--------DTKTTVDAMKLGVKEMKKAYKQVK 124
                  +D   +    +      +  LK        + +TT+ A    +KE++    +VK
Sbjct: 3130 VELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVK 3189

Query: 125  --IDQIEDLQDQLEDMMEDANEIQEALSRSYG----TPELDEDDLE 164
               D++  L D L    + + E+Q AL +       + E D+++LE
Sbjct: 3190 DKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELE 3235



 Score = 31.6 bits (70), Expect = 0.55
 Identities = 30/169 (17%), Positives = 69/169 (40%), Gaps = 28/169 (16%)

Query: 18   TDCIGTVDSRAESIDKKISRLDAE---------LVKYKDQIKKMREGPAKNMVKQKALRV 68
            TD I  ++        ++  L+AE         L+  + +  K   GP +  + Q+  ++
Sbjct: 1942 TDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKL 2001

Query: 69   LKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY---KQVKI 125
            +K+K   + Q + +                  D +  V A+++ V+E    +   +Q K 
Sbjct: 2002 MKEKLEVQCQAEKVRD----------------DLQKQVKALEIDVEEQVSRFIELEQEKN 2045

Query: 126  DQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDEL 174
             ++ DL+ Q + + +   ++++ L       E + D  + E+  L  +L
Sbjct: 2046 TELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQL 2094



 Score = 31.6 bits (70), Expect = 0.55
 Identities = 32/161 (19%), Positives = 74/161 (45%), Gaps = 20/161 (12%)

Query: 34   KISRLDAELVKYKDQIKKM----REGPAKNMVKQKAL-----RVLKQKRMYEQQRDNLA- 83
            ++  L+ E   +KD ++K+    +E  A +   Q  L     +++++K +   Q +    
Sbjct: 2235 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVT 2294

Query: 84   --QQSFNMEQANYTIQS----LKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLED 137
              QQ   +   N  I+     ++D +T ++ +       ++  K+ + ++IE L + +E 
Sbjct: 2295 KLQQQLKITTDNKVIEEKNELIRDLETQIECLMSD----QECVKRNREEEIEQLNEVIEK 2350

Query: 138  MMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADE 178
            + ++   I +  S +  +   + D L+ +LD +  E LA E
Sbjct: 2351 LQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALE 2391



 Score = 30.8 bits (68), Expect = 0.94
 Identities = 32/174 (18%), Positives = 83/174 (47%), Gaps = 24/174 (13%)

Query: 19  DCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQ 78
           D I  ++     ++ K+   +++  K K+++  + E   +    Q+ L  L ++  + ++
Sbjct: 486 DQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILE---EKCALQRQLEDLVEELSFSRE 542

Query: 79  -----RDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQD 133
                R  +A+Q   + +A+ ++ +++D K  + +     KE++  ++     ++ + + 
Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEA----EVTNYKI 598

Query: 134 QLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELL--ADEDSSYLDE 185
           +LE + ++ N + + ++ S           EAEL+ L  +LL   +E+ S L E
Sbjct: 599 KLEMLEKEKNAVLDRMAESQ----------EAELERLRTQLLFSHEEELSKLKE 642



 Score = 28.5 bits (62), Expect = 4.7
 Identities = 30/137 (21%), Positives = 60/137 (43%), Gaps = 7/137 (5%)

Query: 32  DKKISRLDAELVKYKDQIKKMREGPAKNMVKQK-ALRVLKQKR--MYEQQRDNLAQQSFN 88
           DK +  L  ++V+   +IK M+     +  K++ +   +KQ    + E Q+ N     F 
Sbjct: 356 DKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFE 415

Query: 89  MEQANYTIQSLKDTKTTVDAMKLGVKEMK-KAYKQVKIDQIEDLQDQLEDMMEDANEIQE 147
            +      Q   +T+  ++ ++  + EM  +   Q+K + I     Q+E+M        E
Sbjct: 416 TDIVQRMEQ---ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEME 472

Query: 148 ALSRSYGTPELDEDDLE 164
              RSY    ++ED ++
Sbjct: 473 NALRSYSNITVNEDQIK 489


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 37.0 bits (84), Expect = 0.013
 Identities = 38/162 (23%), Positives = 76/162 (46%), Gaps = 25/162 (15%)

Query: 25   DSRAESIDKKISRLDAELVKYKDQIKKMREG-----PAKNMVKQKALRVLKQKRMYEQQR 79
            +++A S+ + +        +++ Q K++R        +K+ V +    + K KR  EQQ 
Sbjct: 1482 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1541

Query: 80   DNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVK-----------EMKKAYKQVKIDQI 128
            + +  Q   +E+    +Q+ +D K  ++     +K           E  +  K++ I Q+
Sbjct: 1542 EEMRTQ---LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV 1598

Query: 129  EDLQDQLEDMMEDANEIQEALS-RSYGTPELDEDDLEAELDA 169
             +L+ +LED  +     Q AL+  S    E+D  DLEA+++A
Sbjct: 1599 RELEAELEDERK-----QRALAVASKKKMEIDLKDLEAQIEA 1635



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 35/157 (22%), Positives = 77/157 (49%), Gaps = 16/157 (10%)

Query: 29   ESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKAL-RVLKQKRM----YEQQRDNLA 83
            + ++K  +RL  EL      +   R+  +    KQK   ++L +++     Y ++RD   
Sbjct: 1416 DKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAE 1475

Query: 84   QQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDAN 143
             ++   E      ++L   +   +A++   +E ++  KQ++ D +EDL    +D+ ++ +
Sbjct: 1476 AEAREKET-----KALSLARALEEALE-AKEEFERQNKQLRAD-MEDLMSSKDDVGKNVH 1528

Query: 144  EIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS 180
            E++    +S    E   +++  +L+ L DEL A ED+
Sbjct: 1529 ELE----KSKRALEQQVEEMRTQLEELEDELQATEDA 1561



 Score = 35.8 bits (81), Expect = 0.029
 Identities = 30/172 (17%), Positives = 76/172 (44%), Gaps = 18/172 (10%)

Query: 24   VDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVL-------------- 69
            ++    ++++++  +  +L + +D+++   +   +  V  +A++                
Sbjct: 1530 LEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEE 1589

Query: 70   KQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIE 129
            K++ + +Q R+  A+     +Q    + S K  +  +  ++  ++   KA  +V I Q+ 
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEV-IKQLR 1648

Query: 130  DLQDQLEDMMEDANEIQEALSRSYGTPELDE---DDLEAELDALGDELLADE 178
             LQ Q++D   +  E + +    +   +  E     LEAE+  L +EL + E
Sbjct: 1649 KLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE 1700



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 34/141 (24%), Positives = 71/141 (50%), Gaps = 20/141 (14%)

Query: 17   LTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKK-MREGPAKNMVKQKALRVLKQKRMY 75
            L +  G V S+ ++    IS L+A++ + ++Q+++  +E  A N + ++  + LK+  M 
Sbjct: 1801 LQELEGAVKSKFKAT---ISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQ 1857

Query: 76   -EQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQ 134
             E +R +  Q    ME+AN  ++ LK             +++++A ++    +    + +
Sbjct: 1858 VEDERRHADQYKEQMEKANARMKQLK-------------RQLEEAEEEAT--RANASRRK 1902

Query: 135  LEDMMEDANEIQEALSRSYGT 155
            L+  ++DA E  E LSR   T
Sbjct: 1903 LQRELDDATEANEGLSREVST 1923



 Score = 32.3 bits (72), Expect = 0.32
 Identities = 33/153 (21%), Positives = 66/153 (43%), Gaps = 14/153 (9%)

Query: 21   IGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGP----AKNMVKQKALRVLKQKRMYE 76
            I   +   + + K++ +L A++  Y+ ++++ R       A++   +K L+ L+ + +  
Sbjct: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEIL-- 1690

Query: 77   QQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLE 136
            Q ++ LA        A      L D  T   + K  + + K+        ++E    QLE
Sbjct: 1691 QLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKR--------RLEARIAQLE 1742

Query: 137  DMMEDANEIQEALSRSYGTPELDEDDLEAELDA 169
            + +E+     E L+  +    L  D L AEL A
Sbjct: 1743 EELEEEQSNMELLNDRFRKTTLQVDTLNAELAA 1775



 Score = 27.7 bits (60), Expect = 8.0
 Identities = 29/136 (21%), Positives = 58/136 (42%), Gaps = 22/136 (16%)

Query: 34  KISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQAN 93
           +++R + EL    +++ K         VK+K  +V  +    E++   L      +E+ N
Sbjct: 846 QVTRQEEELQAKDEELLK---------VKEKQTKVEGELEEMERKHQQL------LEEKN 890

Query: 94  YTIQSLK-DTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRS 152
              + L+ +T+   +A      E  +A    K  ++E++   LE  +E+  E  + L   
Sbjct: 891 ILAEQLQAETELFAEA------EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNE 944

Query: 153 YGTPELDEDDLEAELD 168
               +    DLE +LD
Sbjct: 945 KKKMQAHIQDLEEQLD 960


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,772,707
Number of Sequences: 37866
Number of extensions: 322675
Number of successful extensions: 2267
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 316
Number of HSP's that attempted gapping in prelim test: 1886
Number of HSP's gapped (non-prelim): 710
length of query: 219
length of database: 18,247,518
effective HSP length: 98
effective length of query: 121
effective length of database: 14,536,650
effective search space: 1758934650
effective search space used: 1758934650
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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