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Search of human proteins with 189083742
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]
(526 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens] 1068 0.0
gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens] 1068 0.0
gi|41393187 NADPH oxidase activator 1 [Homo sapiens] 196 4e-50
gi|11321634 CD2-associated protein [Homo sapiens] 77 4e-14
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 66 7e-11
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 66 7e-11
gi|39930351 dynamin binding protein [Homo sapiens] 64 4e-10
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 63 6e-10
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 63 6e-10
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 63 6e-10
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 61 3e-09
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 61 3e-09
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 61 3e-09
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 60 5e-09
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 60 5e-09
gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo... 59 1e-08
gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ... 58 2e-08
gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s... 58 2e-08
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 57 4e-08
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 57 5e-08
gi|21450838 SH3 and cysteine rich domain 3 [Homo sapiens] 56 7e-08
gi|47519798 neutrophil cytosolic factor 4 isoform 1 [Homo sapiens] 56 9e-08
gi|163644267 neutrophil cytosolic factor 4 isoform 2 [Homo sapiens] 56 9e-08
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 55 2e-07
gi|182765466 FCH and double SH3 domains 2 [Homo sapiens] 55 2e-07
gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo... 55 2e-07
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] 54 4e-07
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ... 54 5e-07
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s... 54 5e-07
gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] 54 5e-07
>gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]
Length = 526
Score = 1068 bits (2761), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF 60
MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
Sbjct: 1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF 60
Query: 61 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA 120
TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
Sbjct: 61 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA 120
Query: 121 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG 180
CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
Sbjct: 121 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG 180
Query: 181 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL 240
KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
Sbjct: 181 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL 240
Query: 241 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR 300
EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
Sbjct: 241 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR 300
Query: 301 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY 360
IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
Sbjct: 301 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY 360
Query: 361 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY 420
TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
Sbjct: 361 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY 420
Query: 421 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE 480
CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
Sbjct: 421 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE 480
Query: 481 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV 526
GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
Sbjct: 481 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV 526
>gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens]
Length = 526
Score = 1068 bits (2761), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF 60
MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF
Sbjct: 1 MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAF 60
Query: 61 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA 120
TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA
Sbjct: 61 TRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFA 120
Query: 121 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG 180
CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG
Sbjct: 121 CEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVG 180
Query: 181 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL 240
KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL
Sbjct: 181 KLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRAL 240
Query: 241 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR 300
EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
Sbjct: 241 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR 300
Query: 301 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY 360
IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY
Sbjct: 301 IHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKY 360
Query: 361 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY 420
TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY
Sbjct: 361 TVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNY 420
Query: 421 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE 480
CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE
Sbjct: 421 CLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQE 480
Query: 481 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV 526
GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
Sbjct: 481 GDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV 526
>gi|41393187 NADPH oxidase activator 1 [Homo sapiens]
Length = 483
Score = 196 bits (498), Expect = 4e-50
Identities = 161/528 (30%), Positives = 241/528 (45%), Gaps = 88/528 (16%)
Query: 2 SLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAFT 61
SL + + W+ G A D+ DW AL FS V P +R+CFN GC++ + + A +AF
Sbjct: 3 SLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRAFD 62
Query: 62 RSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFAC 121
+++ +D +AV +FQRG+ +Q ++ A+ D AL QLRG+ IDY LGL+FKL A
Sbjct: 63 QAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQAW 122
Query: 122 EVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVGK 181
EVL+N+A + W +A L A S E + +D A++ V ++ P +P G+
Sbjct: 123 EVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPRGE 182
Query: 182 LFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALE 241
+FRP+ + L D+LGKA VVAS + D G P QPQ P R+L
Sbjct: 183 VFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQG------PGANHDARSLI 236
Query: 242 GEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRI 301
++ R G + + G D + + Q+
Sbjct: 237 MDSPRA------------GTHQGPLDAETEVGADRCTSTAYQEQR--------------- 269
Query: 302 HPQQQPQEESSPQSDIPAPPSSKAPGRPQL-SPGQKQKEEP-----KEVKLSVPMPYTLK 355
PQ + + +P S PG P + PG E+P S P+ T+
Sbjct: 270 -PQVEQVGKQAPLS----------PGLPAMGGPGPGPCEDPAGAGGAGAGGSEPL-VTVT 317
Query: 356 VHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSY-RPRDSNELVPL-SEDSMKDA 413
V +TV ++ + G S +R ++ + L + + +LSY P + VP+ E+S++ A
Sbjct: 318 VQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPGEDGHWVPIPEEESLQRA 377
Query: 414 WGQVKNYC---LTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEA 470
W Q C L L C G P L QV A SY A
Sbjct: 378 W-QDAAACPRGLQLQCRGAGG---------------------RPVL---YQVVAQHSYSA 412
Query: 471 TQPEDLEFQEGDIILVLSK-------VNEEWLEGECKGKVGIFPKVFV 511
PEDL F++GD + VL + V++ WLEG C G++GIFPK FV
Sbjct: 413 QGPEDLGFRQGDTVDVLCEEPDVPLAVDQAWLEGHCDGRIGIFPKCFV 460
>gi|11321634 CD2-associated protein [Homo sapiens]
Length = 639
Score = 77.0 bits (188), Expect = 4e-14
Identities = 71/309 (22%), Positives = 125/309 (40%), Gaps = 65/309 (21%)
Query: 205 VASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPG 264
VAS+V + S G A P P+T I + + +VLF ++P+ ++EL++ G
Sbjct: 78 VASLVQRISTYGLP-----AGGIQPHPQTKNIKKKTKKRQCKVLFEYIPQNEDELELKVG 132
Query: 265 NIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSK 324
+I+ + ++ + W + N + GL P N+++ EL + + E + A P+S
Sbjct: 133 DIIDINEEVEEGWWSGTLNNKLGLFPSNFVK--ELEVTDDGETHEAQDDSETVLAGPTSP 190
Query: 325 APGRPQLS-PGQKQKEEPKEVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKL 383
P +S +PK+++ G+ + + S KL
Sbjct: 191 IPSLGNVSETASGSVTQPKKIR-----------------------GIGFGDIFKEGSVKL 227
Query: 384 ELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEPKESE 443
R ++ + + PL S+ PK ++
Sbjct: 228 RTRTSSSETEEKKPEK----PLILQSL---------------------------GPK-TQ 255
Query: 444 KADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEE--WLEGECKG 501
+ TE ++K LF+YE T ++L F+EG+II ++SK E W GE G
Sbjct: 256 SVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNG 315
Query: 502 KVGIFPKVF 510
K G+FP F
Sbjct: 316 KEGVFPDNF 324
Score = 48.1 bits (113), Expect = 2e-05
Identities = 23/61 (37%), Positives = 33/61 (54%)
Query: 458 KGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATT 517
K Q + LF Y ++LE + GDII + +V E W G K+G+FP FV++ T
Sbjct: 109 KKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVT 168
Query: 518 D 518
D
Sbjct: 169 D 169
Score = 43.5 bits (101), Expect = 5e-04
Identities = 20/49 (40%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
Query: 466 FSYEATQPEDLEFQEGDIILVLSKVNEE-WLEGECKGKVGIFPKVFVED 513
+ Y+A ++L + G+II + K+ EE WLEGE G+ G+FP FV++
Sbjct: 8 YDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKE 56
>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
sapiens]
Length = 628
Score = 66.2 bits (160), Expect = 7e-11
Identities = 56/269 (20%), Positives = 114/269 (42%), Gaps = 50/269 (18%)
Query: 246 RVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQ 305
+V F ++P+ +EL++ G+I+ V+ + + W + NG+ G+ P N+++ +
Sbjct: 67 QVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELG 126
Query: 306 QPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKYTVVMK 365
Q+E +S + S++ G S K + V + P +K
Sbjct: 127 ISQDEQLSKSSLRETTGSESDGGD--SSSTKSEGANGTVATAAIQPKKVK---------- 174
Query: 366 TQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNYCLTLW 425
G+ + + K ++LR ++ N+ +P+
Sbjct: 175 ---GVGFGDI--FKDKPIKLRPRSIEVE------NDFLPV-------------------- 203
Query: 426 CENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIIL 485
E T+G + P + D++ + + K + +F YEA ++L +EGDI+
Sbjct: 204 -EKTIGKK----LPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVT 258
Query: 486 VLSK--VNEEWLEGECKGKVGIFPKVFVE 512
+++K ++ W EGE G+ G+FP FV+
Sbjct: 259 LINKDCIDVGWWEGELNGRRGVFPDNFVK 287
Score = 47.8 bits (112), Expect = 3e-05
Identities = 21/57 (36%), Positives = 34/57 (59%)
Query: 457 KKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVED 513
++ + + FSY ++LE + GDII V+ +V E W EG GK G+FP F+++
Sbjct: 61 RRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKE 117
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/152 (24%), Positives = 66/152 (43%), Gaps = 29/152 (19%)
Query: 222 PQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKG--NDNWAT 279
P P KT R + +V+F + + +EL + G+IV ++ K + W
Sbjct: 212 PATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWE 271
Query: 280 VMFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKA-------------- 325
NG++G+ P N+ +++ P +E + P+ P PPS+
Sbjct: 272 GELNGRRGVFPDNF-----VKLLPPDFEKEGNRPKK--PPPPSAPVIKQGAGTTERKHEI 324
Query: 326 ----PGRPQLSPGQ-KQKEEP-KEVKLSVPMP 351
P RP++ P + ++KE P +E KL + P
Sbjct: 325 KKIPPERPEMLPNRTEEKERPEREPKLDLQKP 356
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 66.2 bits (160), Expect = 7e-11
Identities = 56/269 (20%), Positives = 114/269 (42%), Gaps = 50/269 (18%)
Query: 246 RVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQ 305
+V F ++P+ +EL++ G+I+ V+ + + W + NG+ G+ P N+++ +
Sbjct: 104 QVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELG 163
Query: 306 QPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKYTVVMK 365
Q+E +S + S++ G S K + V + P +K
Sbjct: 164 ISQDEQLSKSSLRETTGSESDGGD--SSSTKSEGANGTVATAAIQPKKVK---------- 211
Query: 366 TQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNYCLTLW 425
G+ + + K ++LR ++ N+ +P+
Sbjct: 212 ---GVGFGDI--FKDKPIKLRPRSIEVE------NDFLPV-------------------- 240
Query: 426 CENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIIL 485
E T+G + P + D++ + + K + +F YEA ++L +EGDI+
Sbjct: 241 -EKTIGKK----LPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVT 295
Query: 486 VLSK--VNEEWLEGECKGKVGIFPKVFVE 512
+++K ++ W EGE G+ G+FP FV+
Sbjct: 296 LINKDCIDVGWWEGELNGRRGVFPDNFVK 324
Score = 47.8 bits (112), Expect = 3e-05
Identities = 21/57 (36%), Positives = 34/57 (59%)
Query: 457 KKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVED 513
++ + + FSY ++LE + GDII V+ +V E W EG GK G+FP F+++
Sbjct: 98 RRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKE 154
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/152 (24%), Positives = 66/152 (43%), Gaps = 29/152 (19%)
Query: 222 PQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKG--NDNWAT 279
P P KT R + +V+F + + +EL + G+IV ++ K + W
Sbjct: 249 PATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWE 308
Query: 280 VMFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKA-------------- 325
NG++G+ P N+ +++ P +E + P+ P PPS+
Sbjct: 309 GELNGRRGVFPDNF-----VKLLPPDFEKEGNRPKK--PPPPSAPVIKQGAGTTERKHEI 361
Query: 326 ----PGRPQLSPGQ-KQKEEP-KEVKLSVPMP 351
P RP++ P + ++KE P +E KL + P
Sbjct: 362 KKIPPERPEMLPNRTEEKERPEREPKLDLQKP 393
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 462 VEAL--FSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVED 513
VEA+ F Y+A ++L G+II + K + W EG+ G+ G+FP FV +
Sbjct: 2 VEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVRE 55
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 63.5 bits (153), Expect = 4e-10
Identities = 33/89 (37%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 434 GFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEE 493
G D P E+ + EP G+ AL+ ++A +P +L+F+ GD I +L+ + +
Sbjct: 224 GEVDTPVGEEEIGPDEDEEEP----GTYGVALYRFQALEPNELDFEVGDKIRILATLEDG 279
Query: 494 WLEGECKGKVGIFPKVFVEDCATTDLEST 522
WLEG KG+ GIFP FV+ C T +E T
Sbjct: 280 WLEGSLKGRTGIFPYRFVKLCPDTRVEET 308
Score = 51.6 bits (122), Expect = 2e-06
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Query: 454 PQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
P+ G Q AL A E+L+F+EGD+I ++ W EGE +G+ GIFP+ FVE
Sbjct: 143 PEYSMG-QARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVE 200
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/69 (37%), Positives = 37/69 (53%)
Query: 456 LKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCA 515
++ GS V A+F + + E+L GDII VL+ V+E WL G+ + G FP FVE
Sbjct: 1 MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVT 60
Query: 516 TTDLESTRR 524
L+ R
Sbjct: 61 IPSLKEGER 69
Score = 35.8 bits (81), Expect = 0.099
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 4/79 (5%)
Query: 224 AAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLK----KGNDNWAT 279
A P R P+ A + + ++ F EL V + +L+ GN W
Sbjct: 1497 AQAPEDRSTEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWL 1556
Query: 280 VMFNGQKGLVPCNYLEPVE 298
NG+KG VP NY+ E
Sbjct: 1557 AEVNGKKGYVPSNYIRKTE 1575
Score = 32.0 bits (71), Expect = 1.4
Identities = 17/58 (29%), Positives = 27/58 (46%)
Query: 242 GEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVEL 299
G R +F F P EEL + G+I+ VL ++ W G P +++E V +
Sbjct: 4 GSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTI 61
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 63.2 bits (152), Expect = 6e-10
Identities = 67/283 (23%), Positives = 115/283 (40%), Gaps = 24/283 (8%)
Query: 245 HRVLFGFVPETKEELQVMPGNIVFVLKK--GNDNWATVMFNGQKGLVPCNYLEPVELRIH 302
+R L+ F +E+ G+I+ V +K G W F G G PCNY+E +
Sbjct: 735 YRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM----- 789
Query: 303 PQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEV---------KLSVPMPYT 353
P + ++ SP+ + P S + P +P V L+V +
Sbjct: 790 PSSENEKAVSPKKALLPPTVSLSATSTSSEP--LSSNQPASVTDYQNVSFSNLTVNTSWQ 847
Query: 354 LKVHYKYTVVM-KTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKD 412
K + TV P QV + + + K ++ ++++ + E
Sbjct: 848 KKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENW 907
Query: 413 AWGQV---KNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYE 469
+G+V + + + + G + +EP E+ A N + T G + AL+ Y
Sbjct: 908 WFGEVHGGRGWFPKSYVKIIPGSEVKREEP-EALYAAVNKKPTSAAYSVGEEYIALYPYS 966
Query: 470 ATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
+ +P DL F EG+ ILV K + EW G + GIFP +V+
Sbjct: 967 SVEPGDLTFTEGEEILVTQK-DGEWWTGSIGDRSGIFPSNYVK 1008
Score = 49.3 bits (116), Expect = 9e-06
Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Query: 448 NNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFP 507
+++ P QV A++ Y A ++L F +G +I V++K + +W +GE G G+FP
Sbjct: 1091 SSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFP 1150
Query: 508 KVFVEDCATTDLESTRR 524
+V+ TTD + +++
Sbjct: 1151 SNYVK--MTTDSDPSQQ 1165
Score = 42.7 bits (99), Expect = 8e-04
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 437 DEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQP------EDLEFQEGDIILVLSKV 490
+E K EK + T + + KK L +Y A P +++ F GDII V K
Sbjct: 704 EERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKT 763
Query: 491 NEE--WLEGECKGKVGIFPKVFVEDCATTDLE 520
E WL G +G G FP +VE +++ E
Sbjct: 764 VGEPGWLYGSFQGNFGWFPCNYVEKMPSSENE 795
Score = 35.4 bits (80), Expect = 0.13
Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 425 WCENTVGDQG--FPD---EPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQ 479
W ++GD+ FP +PK+ E + +++ KK + +Y A+ E L
Sbjct: 990 WWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASN-KKPEIAQVTSAYVASGSEQLSLA 1048
Query: 480 EGDIILVLSKVNEEWLEGECKGK 502
G +IL+L K W +GE + +
Sbjct: 1049 PGQLILILKKNTSGWWQGELQAR 1071
Score = 33.5 bits (75), Expect = 0.49
Identities = 13/48 (27%), Positives = 25/48 (52%)
Query: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
++ + ++EL G ++ V+ K + +W NG GL P NY++
Sbjct: 1108 MYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1155
Score = 30.8 bits (68), Expect = 3.2
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 20/91 (21%)
Query: 210 DQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFV 269
DQ+SF A++ K PEI + V +V E+L + PG ++ +
Sbjct: 1011 DQESFGS-------ASKSGASNKKPEIAQ--------VTSAYVASGSEQLSLAPGQLILI 1055
Query: 270 LKKGNDNW--ATVMFNG---QKGLVPCNYLE 295
LKK W + G QKG P ++++
Sbjct: 1056 LKKNTSGWWQGELQARGKKRQKGWFPASHVK 1086
Score = 30.4 bits (67), Expect = 4.2
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 4/97 (4%)
Query: 242 GEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRI 301
GE + L+ + +L G + V +K + W T + G+ P NY++P +
Sbjct: 956 GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGE-WWTGSIGDRSGIFPSNYVKPKDQES 1014
Query: 302 HPQQQPQEESSPQSDIPAPPSS-KAPGRPQLS--PGQ 335
S+ + +I S+ A G QLS PGQ
Sbjct: 1015 FGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQ 1051
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 63.2 bits (152), Expect = 6e-10
Identities = 67/283 (23%), Positives = 115/283 (40%), Gaps = 24/283 (8%)
Query: 245 HRVLFGFVPETKEELQVMPGNIVFVLKK--GNDNWATVMFNGQKGLVPCNYLEPVELRIH 302
+R L+ F +E+ G+I+ V +K G W F G G PCNY+E +
Sbjct: 762 YRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM----- 816
Query: 303 PQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEV---------KLSVPMPYT 353
P + ++ SP+ + P S + P +P V L+V +
Sbjct: 817 PSSENEKAVSPKKALLPPTVSLSATSTSSEP--LSSNQPASVTDYQNVSFSNLTVNTSWQ 874
Query: 354 LKVHYKYTVVM-KTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKD 412
K + TV P QV + + + K ++ ++++ + E
Sbjct: 875 KKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENW 934
Query: 413 AWGQV---KNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYE 469
+G+V + + + + G + +EP E+ A N + T G + AL+ Y
Sbjct: 935 WFGEVHGGRGWFPKSYVKIIPGSEVKREEP-EALYAAVNKKPTSAAYSVGEEYIALYPYS 993
Query: 470 ATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
+ +P DL F EG+ ILV K + EW G + GIFP +V+
Sbjct: 994 SVEPGDLTFTEGEEILVTQK-DGEWWTGSIGDRSGIFPSNYVK 1035
Score = 49.3 bits (116), Expect = 9e-06
Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Query: 448 NNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFP 507
+++ P QV A++ Y A ++L F +G +I V++K + +W +GE G G+FP
Sbjct: 1118 SSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFP 1177
Query: 508 KVFVEDCATTDLESTRR 524
+V+ TTD + +++
Sbjct: 1178 SNYVK--MTTDSDPSQQ 1192
Score = 42.7 bits (99), Expect = 8e-04
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 437 DEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQP------EDLEFQEGDIILVLSKV 490
+E K EK + T + + KK L +Y A P +++ F GDII V K
Sbjct: 731 EERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKT 790
Query: 491 NEE--WLEGECKGKVGIFPKVFVEDCATTDLE 520
E WL G +G G FP +VE +++ E
Sbjct: 791 VGEPGWLYGSFQGNFGWFPCNYVEKMPSSENE 822
Score = 35.4 bits (80), Expect = 0.13
Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 425 WCENTVGDQG--FPD---EPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQ 479
W ++GD+ FP +PK+ E + +++ KK + +Y A+ E L
Sbjct: 1017 WWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASN-KKPEIAQVTSAYVASGSEQLSLA 1075
Query: 480 EGDIILVLSKVNEEWLEGECKGK 502
G +IL+L K W +GE + +
Sbjct: 1076 PGQLILILKKNTSGWWQGELQAR 1098
Score = 33.5 bits (75), Expect = 0.49
Identities = 13/48 (27%), Positives = 25/48 (52%)
Query: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
++ + ++EL G ++ V+ K + +W NG GL P NY++
Sbjct: 1135 MYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1182
Score = 30.8 bits (68), Expect = 3.2
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 20/91 (21%)
Query: 210 DQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFV 269
DQ+SF A++ K PEI + V +V E+L + PG ++ +
Sbjct: 1038 DQESFGS-------ASKSGASNKKPEIAQ--------VTSAYVASGSEQLSLAPGQLILI 1082
Query: 270 LKKGNDNW--ATVMFNG---QKGLVPCNYLE 295
LKK W + G QKG P ++++
Sbjct: 1083 LKKNTSGWWQGELQARGKKRQKGWFPASHVK 1113
Score = 30.4 bits (67), Expect = 4.2
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 4/97 (4%)
Query: 242 GEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRI 301
GE + L+ + +L G + V +K + W T + G+ P NY++P +
Sbjct: 983 GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGE-WWTGSIGDRSGIFPSNYVKPKDQES 1041
Query: 302 HPQQQPQEESSPQSDIPAPPSS-KAPGRPQLS--PGQ 335
S+ + +I S+ A G QLS PGQ
Sbjct: 1042 FGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQ 1078
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 63.2 bits (152), Expect = 6e-10
Identities = 67/283 (23%), Positives = 115/283 (40%), Gaps = 24/283 (8%)
Query: 245 HRVLFGFVPETKEELQVMPGNIVFVLKK--GNDNWATVMFNGQKGLVPCNYLEPVELRIH 302
+R L+ F +E+ G+I+ V +K G W F G G PCNY+E +
Sbjct: 762 YRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKM----- 816
Query: 303 PQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEV---------KLSVPMPYT 353
P + ++ SP+ + P S + P +P V L+V +
Sbjct: 817 PSSENEKAVSPKKALLPPTVSLSATSTSSEP--LSSNQPASVTDYQNVSFSNLTVNTSWQ 874
Query: 354 LKVHYKYTVVM-KTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKD 412
K + TV P QV + + + K ++ ++++ + E
Sbjct: 875 KKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITVLEQQENW 934
Query: 413 AWGQV---KNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYE 469
+G+V + + + + G + +EP E+ A N + T G + AL+ Y
Sbjct: 935 WFGEVHGGRGWFPKSYVKIIPGSEVKREEP-EALYAAVNKKPTSAAYSVGEEYIALYPYS 993
Query: 470 ATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
+ +P DL F EG+ ILV K + EW G + GIFP +V+
Sbjct: 994 SVEPGDLTFTEGEEILVTQK-DGEWWTGSIGDRSGIFPSNYVK 1035
Score = 49.3 bits (116), Expect = 9e-06
Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Query: 448 NNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFP 507
+++ P QV A++ Y A ++L F +G +I V++K + +W +GE G G+FP
Sbjct: 1118 SSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFP 1177
Query: 508 KVFVEDCATTDLESTRR 524
+V+ TTD + +++
Sbjct: 1178 SNYVK--MTTDSDPSQQ 1192
Score = 42.7 bits (99), Expect = 8e-04
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 8/92 (8%)
Query: 437 DEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQP------EDLEFQEGDIILVLSKV 490
+E K EK + T + + KK L +Y A P +++ F GDII V K
Sbjct: 731 EERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKT 790
Query: 491 NEE--WLEGECKGKVGIFPKVFVEDCATTDLE 520
E WL G +G G FP +VE +++ E
Sbjct: 791 VGEPGWLYGSFQGNFGWFPCNYVEKMPSSENE 822
Score = 35.4 bits (80), Expect = 0.13
Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 425 WCENTVGDQG--FPD---EPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQ 479
W ++GD+ FP +PK+ E + +++ KK + +Y A+ E L
Sbjct: 1017 WWTGSIGDRSGIFPSNYVKPKDQESFGSASKSGASN-KKPEIAQVTSAYVASGSEQLSLA 1075
Query: 480 EGDIILVLSKVNEEWLEGECKGK 502
G +IL+L K W +GE + +
Sbjct: 1076 PGQLILILKKNTSGWWQGELQAR 1098
Score = 33.5 bits (75), Expect = 0.49
Identities = 13/48 (27%), Positives = 25/48 (52%)
Query: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
++ + ++EL G ++ V+ K + +W NG GL P NY++
Sbjct: 1135 MYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVK 1182
Score = 30.8 bits (68), Expect = 3.2
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 20/91 (21%)
Query: 210 DQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFV 269
DQ+SF A++ K PEI + V +V E+L + PG ++ +
Sbjct: 1038 DQESFGS-------ASKSGASNKKPEIAQ--------VTSAYVASGSEQLSLAPGQLILI 1082
Query: 270 LKKGNDNW--ATVMFNG---QKGLVPCNYLE 295
LKK W + G QKG P ++++
Sbjct: 1083 LKKNTSGWWQGELQARGKKRQKGWFPASHVK 1113
Score = 30.4 bits (67), Expect = 4.2
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 4/97 (4%)
Query: 242 GEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRI 301
GE + L+ + +L G + V +K + W T + G+ P NY++P +
Sbjct: 983 GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGE-WWTGSIGDRSGIFPSNYVKPKDQES 1041
Query: 302 HPQQQPQEESSPQSDIPAPPSS-KAPGRPQLS--PGQ 335
S+ + +I S+ A G QLS PGQ
Sbjct: 1042 FGSASKSGASNKKPEIAQVTSAYVASGSEQLSLAPGQ 1078
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 60.8 bits (146), Expect = 3e-09
Identities = 29/70 (41%), Positives = 39/70 (55%)
Query: 443 EKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGK 502
E + + KGS+ A F Y Q ++L F EG+II++ VNEEW GE +G+
Sbjct: 498 EGGNGKRECVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGR 557
Query: 503 VGIFPKVFVE 512
GIFP FVE
Sbjct: 558 TGIFPLNFVE 567
Score = 55.8 bits (133), Expect = 9e-08
Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 425 WCENTVGDQG--FPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGD 482
WC + D+ FP A+A + + KG + +AL+ + ++L F+ GD
Sbjct: 639 WCRGRLQDREGIFPAVFVRPCPAEAKSMLAI--VPKGRKAKALYDFRGENEDELSFKAGD 696
Query: 483 IILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
II L V+++W+ GE GK GIFPK +++
Sbjct: 697 IITELESVDDDWMSGELMGKSGIFPKNYIQ 726
Score = 52.8 bits (125), Expect = 8e-07
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Query: 439 PKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGE 498
P +++K D+ + + L EAL S+ A +DL F+ GD I +L +++ +W G
Sbjct: 585 PLKTKKEDSGSNSQVNSLP-AEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGR 643
Query: 499 CKGKVGIFPKVFVEDC 514
+ + GIFP VFV C
Sbjct: 644 LQDREGIFPAVFVRPC 659
Score = 47.0 bits (110), Expect = 4e-05
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 436 PDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWL 495
P++P ++K P L + A Q +DL G+I+ +L K++ +W
Sbjct: 424 PNDPSHAQK---------PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWY 474
Query: 496 EGECKGKVGIFPKVFVE 512
G C+ ++GIFP +V+
Sbjct: 475 RGNCRNQIGIFPANYVK 491
Score = 42.7 bits (99), Expect = 8e-04
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 249 FGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVE 298
F ++ E K+EL G I+ + + N+ WA G+ G+ P N++EPVE
Sbjct: 521 FEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVE 570
Score = 38.1 bits (87), Expect = 0.020
Identities = 16/59 (27%), Positives = 34/59 (57%)
Query: 241 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVEL 299
+G + L+ F E ++EL G+I+ L+ +D+W + G+ G+ P NY++ +++
Sbjct: 672 KGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQI 730
Score = 33.9 bits (76), Expect = 0.38
Identities = 16/51 (31%), Positives = 28/51 (54%)
Query: 247 VLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPV 297
VL F E ++L + G IV++L+K + +W Q G+ P NY++ +
Sbjct: 443 VLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVI 493
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 60.8 bits (146), Expect = 3e-09
Identities = 29/70 (41%), Positives = 39/70 (55%)
Query: 443 EKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGK 502
E + + KGS+ A F Y Q ++L F EG+II++ VNEEW GE +G+
Sbjct: 534 EGGNGKRECVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGR 593
Query: 503 VGIFPKVFVE 512
GIFP FVE
Sbjct: 594 TGIFPLNFVE 603
Score = 55.8 bits (133), Expect = 9e-08
Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 425 WCENTVGDQG--FPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGD 482
WC + D+ FP A+A + + KG + +AL+ + ++L F+ GD
Sbjct: 675 WCRGRLQDREGIFPAVFVRPCPAEAKSMLAI--VPKGRKAKALYDFRGENEDELSFKAGD 732
Query: 483 IILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
II L V+++W+ GE GK GIFPK +++
Sbjct: 733 IITELESVDDDWMSGELMGKSGIFPKNYIQ 762
Score = 52.8 bits (125), Expect = 8e-07
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Query: 439 PKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGE 498
P +++K D+ + + L EAL S+ A +DL F+ GD I +L +++ +W G
Sbjct: 621 PLKTKKEDSGSNSQVNSLP-AEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGR 679
Query: 499 CKGKVGIFPKVFVEDC 514
+ + GIFP VFV C
Sbjct: 680 LQDREGIFPAVFVRPC 695
Score = 47.0 bits (110), Expect = 4e-05
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 436 PDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWL 495
P++P ++K P L + A Q +DL G+I+ +L K++ +W
Sbjct: 460 PNDPSHAQK---------PVDSGAPHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWY 510
Query: 496 EGECKGKVGIFPKVFVE 512
G C+ ++GIFP +V+
Sbjct: 511 RGNCRNQIGIFPANYVK 527
Score = 42.7 bits (99), Expect = 8e-04
Identities = 18/50 (36%), Positives = 29/50 (58%)
Query: 249 FGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVE 298
F ++ E K+EL G I+ + + N+ WA G+ G+ P N++EPVE
Sbjct: 557 FEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVE 606
Score = 38.1 bits (87), Expect = 0.020
Identities = 16/59 (27%), Positives = 34/59 (57%)
Query: 241 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVEL 299
+G + L+ F E ++EL G+I+ L+ +D+W + G+ G+ P NY++ +++
Sbjct: 708 KGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQI 766
Score = 33.9 bits (76), Expect = 0.38
Identities = 16/51 (31%), Positives = 28/51 (54%)
Query: 247 VLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPV 297
VL F E ++L + G IV++L+K + +W Q G+ P NY++ +
Sbjct: 479 VLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVI 529
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 60.8 bits (146), Expect = 3e-09
Identities = 29/70 (41%), Positives = 39/70 (55%)
Query: 443 EKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGK 502
E + + KGS+ A F Y Q ++L F EG+II++ VNEEW GE +G+
Sbjct: 557 EGGNGKRECVSSHCVKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGR 616
Query: 503 VGIFPKVFVE 512
GIFP FVE
Sbjct: 617 TGIFPLNFVE 626
Score = 55.8 bits (133), Expect = 9e-08
Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 425 WCENTVGDQG--FPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGD 482
WC + D+ FP A+A + + KG + +AL+ + ++L F+ GD
Sbjct: 698 WCRGRLQDREGIFPAVFVRPCPAEAKSMLAI--VPKGRKAKALYDFRGENEDELSFKAGD 755
Query: 483 IILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
II L V+++W+ GE GK GIFPK +++
Sbjct: 756 IITELESVDDDWMSGELMGKSGIFPKNYIQ 785
Score = 53.9 bits (128), Expect = 4e-07
Identities = 73/328 (22%), Positives = 128/328 (39%), Gaps = 38/328 (11%)
Query: 221 QPQAAEPPPRPKTPEIFRALEGEAHRVLF-GFVPETKEELQVMPGNIVFVLKKGNDNWAT 279
Q P P+P P + + H + V + EL G+++ +LK+ +N+
Sbjct: 395 QDPVLPPRPKPGHPLYSKYMLSVPHGIANEDIVSQNPGELSCKRGDVLVMLKQTENNYLE 454
Query: 280 VMFNGQKGLVPCNYLEPVE-LRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQK 338
G V + ++ + L H + +P + S Q P S AP L ++
Sbjct: 455 CQKGEDTGRVHLSQMKIITPLDEHLRSRPNDPSHAQK----PVDSGAPHAVVLHDFPAEQ 510
Query: 339 EEPKEVKLSVPMPYTLKVHYK-YTVVMKTQPGL-PYSQVRDMV------SKKLELRLEHT 390
+ + + K+ Y + Q G+ P + V+ ++ + K E H
Sbjct: 511 VDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVIIDIPEGGNGKRECVSSHC 570
Query: 391 KLSYRPRDSNELVPLSEDSMKDAWGQV---KNYCLTLWCENTVGDQ------GFPDEPKE 441
R E + +D + + G++ K Y W V + F + ++
Sbjct: 571 VKGSRCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVED 630
Query: 442 SEKADANNQTTEPQLK-------KGSQV--------EALFSYEATQPEDLEFQEGDIILV 486
+ AN +T+ LK SQV EAL S+ A +DL F+ GD I +
Sbjct: 631 YPTSGANVLSTKVPLKTKKEDSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQI 690
Query: 487 LSKVNEEWLEGECKGKVGIFPKVFVEDC 514
L +++ +W G + + GIFP VFV C
Sbjct: 691 LERLDSDWCRGRLQDREGIFPAVFVRPC 718
Score = 38.1 bits (87), Expect = 0.020
Identities = 16/59 (27%), Positives = 34/59 (57%)
Query: 241 EGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVEL 299
+G + L+ F E ++EL G+I+ L+ +D+W + G+ G+ P NY++ +++
Sbjct: 731 KGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQI 789
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 60.1 bits (144), Expect = 5e-09
Identities = 74/327 (22%), Positives = 121/327 (37%), Gaps = 76/327 (23%)
Query: 245 HRVLFGFVPETKEELQVMPGNIVFVL-------KKGNDNWATVMFNGQKGLVPCNYLEPV 297
+R L+ F + +E+ + PG+IV V + G W G+ G P NY E +
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 298 ELRIHPQQQPQEESSPQSDIPAP---------PSSKAPGRPQLSPGQ----------KQK 338
P P + + + PAP P + P +P
Sbjct: 805 PENEVPA--PVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPTSTN 862
Query: 339 EEPK---------EVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEH 389
E+P+ + L+VP L+ +T T G S V +K+E
Sbjct: 863 EKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATAT--GSSPSPVLGQ-GEKVEGLQAQ 919
Query: 390 TKLSYRPRDSNELVPLSED-----SMKDAWGQVKNYCLTLWCENTVGDQG-FPDEP---- 439
+R + N L D +D W W G +G FP
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMW----------WFGEVQGQKGWFPKSYVKLI 969
Query: 440 ----KESEKADANNQTTEPQLKK-----------GSQVEALFSYEATQPEDLEFQEGDII 484
++S D+ + + LK+ G + A+++YE+++ DL FQ+GD+I
Sbjct: 970 SGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVI 1029
Query: 485 LVLSKVNEEWLEGECKGKVGIFPKVFV 511
LV +K + +W G K G+FP +V
Sbjct: 1030 LV-TKKDGDWWTGTVGDKAGVFPSNYV 1055
Score = 52.0 bits (123), Expect = 1e-06
Identities = 24/64 (37%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Query: 461 QVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLE 520
QV ++ Y A ++L F +G II VL+K + +W +GE G+VG+FP +V+ TTD++
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK--LTTDMD 1216
Query: 521 STRR 524
+++
Sbjct: 1217 PSQQ 1220
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 11/98 (11%)
Query: 425 WCENTVGDQG--FPDEP---KESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQ 479
W TVGD+ FP K+SE + +T KK + + SY AT PE L
Sbjct: 1038 WWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLG-KKPEIAQVIASYTATGPEQLTLA 1096
Query: 480 EGDIILVLSKVNEEWLEGEC-----KGKVGIFPKVFVE 512
G +IL+ K W EGE K ++G FP +V+
Sbjct: 1097 PGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1134
Score = 39.7 bits (91), Expect = 0.007
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 464 ALFSYEATQPEDLEFQEGDIILVLSKVNEE-------WLEGECKGKVGIFPKVFVE 512
AL+ +E+ +++ Q GDI++V + +E WL GE KGK G FP + E
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAE 802
Score = 36.6 bits (83), Expect = 0.058
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQ 306
++ + + +EL G I+ VL K + +W NGQ GL P NY++ + + P QQ
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK-LTTDMDPSQQ 1220
Score = 30.8 bits (68), Expect = 3.2
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 243 EAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW--ATVMFNGQK---GLVPCNY---L 294
E +V+ + E+L + PG ++ + KK W + G+K G P NY L
Sbjct: 1077 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 1136
Query: 295 EPVELRIHPQQQPQ 308
P +I P + P+
Sbjct: 1137 SPGTSKITPTEPPK 1150
Score = 30.0 bits (66), Expect = 5.4
Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 230 RPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLV 289
R +P + GE ++ + + +L G+++ V KK D W T + G+
Sbjct: 992 RVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVF 1050
Query: 290 PCNYL 294
P NY+
Sbjct: 1051 PSNYV 1055
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 60.1 bits (144), Expect = 5e-09
Identities = 74/327 (22%), Positives = 121/327 (37%), Gaps = 76/327 (23%)
Query: 245 HRVLFGFVPETKEELQVMPGNIVFVL-------KKGNDNWATVMFNGQKGLVPCNYLEPV 297
+R L+ F + +E+ + PG+IV V + G W G+ G P NY E +
Sbjct: 745 YRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKI 804
Query: 298 ELRIHPQQQPQEESSPQSDIPAP---------PSSKAPGRPQLSPGQ----------KQK 338
P P + + + PAP P + P +P
Sbjct: 805 PENEVPA--PVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPTSTN 862
Query: 339 EEPK---------EVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEH 389
E+P+ + L+VP L+ +T T G S V +K+E
Sbjct: 863 EKPETDNWDAWAAQPSLTVPSAGQLRQRSAFTPATAT--GSSPSPVLGQ-GEKVEGLQAQ 919
Query: 390 TKLSYRPRDSNELVPLSED-----SMKDAWGQVKNYCLTLWCENTVGDQG-FPDEP---- 439
+R + N L D +D W W G +G FP
Sbjct: 920 ALYPWRAKKDNHLNFNKNDVITVLEQQDMW----------WFGEVQGQKGWFPKSYVKLI 969
Query: 440 ----KESEKADANNQTTEPQLKK-----------GSQVEALFSYEATQPEDLEFQEGDII 484
++S D+ + + LK+ G + A+++YE+++ DL FQ+GD+I
Sbjct: 970 SGPIRKSTSMDSGSSESPASLKRVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVI 1029
Query: 485 LVLSKVNEEWLEGECKGKVGIFPKVFV 511
LV +K + +W G K G+FP +V
Sbjct: 1030 LV-TKKDGDWWTGTVGDKAGVFPSNYV 1055
Score = 52.0 bits (123), Expect = 1e-06
Identities = 24/64 (37%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Query: 461 QVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLE 520
QV ++ Y A ++L F +G II VL+K + +W +GE G+VG+FP +V+ TTD++
Sbjct: 1159 QVIGMYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK--LTTDMD 1216
Query: 521 STRR 524
+++
Sbjct: 1217 PSQQ 1220
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 11/98 (11%)
Query: 425 WCENTVGDQG--FPDEP---KESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQ 479
W TVGD+ FP K+SE + +T KK + + SY AT PE L
Sbjct: 1038 WWTGTVGDKAGVFPSNYVRLKDSEGSGTAGKTGSLG-KKPEIAQVIASYTATGPEQLTLA 1096
Query: 480 EGDIILVLSKVNEEWLEGEC-----KGKVGIFPKVFVE 512
G +IL+ K W EGE K ++G FP +V+
Sbjct: 1097 PGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVK 1134
Score = 39.7 bits (91), Expect = 0.007
Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 7/56 (12%)
Query: 464 ALFSYEATQPEDLEFQEGDIILVLSKVNEE-------WLEGECKGKVGIFPKVFVE 512
AL+ +E+ +++ Q GDI++V + +E WL GE KGK G FP + E
Sbjct: 747 ALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAE 802
Score = 36.6 bits (83), Expect = 0.058
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQ 306
++ + + +EL G I+ VL K + +W NGQ GL P NY++ + + P QQ
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKEDPDWWKGEVNGQVGLFPSNYVK-LTTDMDPSQQ 1220
Score = 30.8 bits (68), Expect = 3.2
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 243 EAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW--ATVMFNGQK---GLVPCNY---L 294
E +V+ + E+L + PG ++ + KK W + G+K G P NY L
Sbjct: 1077 EIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLL 1136
Query: 295 EPVELRIHPQQQPQ 308
P +I P + P+
Sbjct: 1137 SPGTSKITPTEPPK 1150
Score = 30.0 bits (66), Expect = 5.4
Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 230 RPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLV 289
R +P + GE ++ + + +L G+++ V KK D W T + G+
Sbjct: 992 RVASPAAKPVVSGEEFIAMYTYESSEQGDLTFQQGDVILVTKKDGD-WWTGTVGDKAGVF 1050
Query: 290 PCNYL 294
P NY+
Sbjct: 1051 PSNYV 1055
>gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo
sapiens]
Length = 323
Score = 58.9 bits (141), Expect = 1e-08
Identities = 30/75 (40%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Query: 439 PKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNE--EWLE 496
P++S N ++ L + +V AL+S+E QP DL FQ GD I V+SK + +W E
Sbjct: 246 PQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWE 305
Query: 497 GECKGKVGIFPKVFV 511
G+ +G+ GIFP +V
Sbjct: 306 GKLRGQTGIFPANYV 320
>gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo
sapiens]
Length = 671
Score = 57.8 bits (138), Expect = 2e-08
Identities = 24/78 (30%), Positives = 43/78 (55%)
Query: 435 FPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEW 494
+P ++ ++ + KK F ++A P++L Q+GDI+ + +V++ W
Sbjct: 358 YPSSTRDPSASNGGGSPARREEKKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNW 417
Query: 495 LEGECKGKVGIFPKVFVE 512
LEGE G++GIFP +VE
Sbjct: 418 LEGEHHGRLGIFPANYVE 435
Score = 47.8 bits (112), Expect = 3e-05
Identities = 66/304 (21%), Positives = 115/304 (37%), Gaps = 53/304 (17%)
Query: 243 EAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIH 302
+A R+ F F ++ +EL + G+IV++ K+ + NW +G+ G+ P NY+E +
Sbjct: 383 KAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVEVL----- 437
Query: 303 PQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVH----- 357
P +IP P K P L G+ + + L V + + H
Sbjct: 438 ----------PADEIPKP--IKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIR 485
Query: 358 ------YKYTVVMKTQPGL-PYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSM 410
Y+ + + G+ P S V+ +L L + +L PR + S
Sbjct: 486 KVNENWYEGRITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSS 545
Query: 411 KDAWGQVKNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKG----------- 459
A + + L + + GF +E N T P L
Sbjct: 546 PSALRSPAD-PIDLGGQTSPRRTGFSFPTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGT 604
Query: 460 -----SQV-----EALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECK--GKVGIFP 507
SQ+ A++ Y ++LE +EGD + V+ + ++ W G + K G FP
Sbjct: 605 SSPNTSQIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFP 664
Query: 508 KVFV 511
+V
Sbjct: 665 GNYV 668
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 435 FPDEPKESEKADANNQTTEP---QLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVN 491
FP E AD + +P Q+ + + A ++++ +L F++G+ I ++ KVN
Sbjct: 429 FPANYVEVLPADEIPKPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIRKVN 488
Query: 492 EEWLEGEC--KGKVGIFPKVFVE 512
E W EG G+ GIFP +V+
Sbjct: 489 ENWYEGRITGTGRQGIFPASYVQ 511
Score = 33.1 bits (74), Expect = 0.64
Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 245 HRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW-ATVMFNGQK-GLVPCNYLEPV 297
+R ++ + P+ ++EL++ G+ V V+++ +D W V QK G P NY+ PV
Sbjct: 617 YRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 671
>gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo
sapiens]
Length = 329
Score = 57.8 bits (138), Expect = 2e-08
Identities = 24/78 (30%), Positives = 43/78 (55%)
Query: 435 FPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEW 494
+P ++ ++ + KK F ++A P++L Q+GDI+ + +V++ W
Sbjct: 16 YPSSTRDPSASNGGGSPARREEKKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNW 75
Query: 495 LEGECKGKVGIFPKVFVE 512
LEGE G++GIFP +VE
Sbjct: 76 LEGEHHGRLGIFPANYVE 93
Score = 47.8 bits (112), Expect = 3e-05
Identities = 66/304 (21%), Positives = 115/304 (37%), Gaps = 53/304 (17%)
Query: 243 EAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIH 302
+A R+ F F ++ +EL + G+IV++ K+ + NW +G+ G+ P NY+E +
Sbjct: 41 KAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVEVL----- 95
Query: 303 PQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVH----- 357
P +IP P K P L G+ + + L V + + H
Sbjct: 96 ----------PADEIPKP--IKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIR 143
Query: 358 ------YKYTVVMKTQPGL-PYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSM 410
Y+ + + G+ P S V+ +L L + +L PR + S
Sbjct: 144 KVNENWYEGRITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSS 203
Query: 411 KDAWGQVKNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKG----------- 459
A + + L + + GF +E N T P L
Sbjct: 204 PSALRSPAD-PIDLGGQTSPRRTGFSFPTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGT 262
Query: 460 -----SQV-----EALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECK--GKVGIFP 507
SQ+ A++ Y ++LE +EGD + V+ + ++ W G + K G FP
Sbjct: 263 SSPNTSQIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFP 322
Query: 508 KVFV 511
+V
Sbjct: 323 GNYV 326
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 435 FPDEPKESEKADANNQTTEP---QLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVN 491
FP E AD + +P Q+ + + A ++++ +L F++G+ I ++ KVN
Sbjct: 87 FPANYVEVLPADEIPKPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIRKVN 146
Query: 492 EEWLEGEC--KGKVGIFPKVFVE 512
E W EG G+ GIFP +V+
Sbjct: 147 ENWYEGRITGTGRQGIFPASYVQ 169
Score = 33.1 bits (74), Expect = 0.64
Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 245 HRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW-ATVMFNGQK-GLVPCNYLEPV 297
+R ++ + P+ ++EL++ G+ V V+++ +D W V QK G P NY+ PV
Sbjct: 275 YRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 329
>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
sapiens]
Length = 644
Score = 57.0 bits (136), Expect = 4e-08
Identities = 62/282 (21%), Positives = 111/282 (39%), Gaps = 46/282 (16%)
Query: 276 NWATVMFNGQKGLV--PCNYLEPVELRIHPQQQPQ---------EESSPQS----DIPAP 320
+W MF Q +V P Y P + HP + Q ++SP + P P
Sbjct: 182 DWYKTMFK-QIHMVHKPGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFKDASSPVP 240
Query: 321 PSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKYTVVMKTQPGL--------PY 372
P P P L P + E + T K + + + +PG P
Sbjct: 241 PPHVPPPVPPLRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPA 300
Query: 373 SQVRDMVSKKLELRLEHTKLSYRPRDSNELVPL--------SEDSMKDAWGQVK--NYCL 422
S + + + LE + ++ R + P + + + + G+V
Sbjct: 301 SLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSST 360
Query: 423 TLWCENTVGDQGFPDEPKESEKADANNQT------TEPQLKKGSQ------VEALFSYEA 470
TL T P K+ E + + T + P+ ++G+ +A++ ++A
Sbjct: 361 TLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKA 420
Query: 471 TQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
++L F++GD + +L K+++ W EGE G+VGIFP +VE
Sbjct: 421 QTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVE 462
Score = 52.0 bits (123), Expect = 1e-06
Identities = 67/300 (22%), Positives = 117/300 (39%), Gaps = 69/300 (23%)
Query: 227 PPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQK 286
P R TPE E + ++ F +T +EL G+ V++L+K + NW +G+
Sbjct: 398 PRERRGTPE----KEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRV 453
Query: 287 GLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKL 346
G+ P +Y+E + PP P RP P Q P E+
Sbjct: 454 GIFPISYVEKL---------------------TPPEKAQPARPP-PPAQ-----PGEIGE 486
Query: 347 SVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLS 406
++ Y + + L R ++ K+++ K+ R + P+S
Sbjct: 487 AI-------AKYNFNADTNVELSLRKGD-RVILLKRVDQNWYEGKIPGTNRQG--IFPVS 536
Query: 407 EDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEP-KESEKAD-----ANNQTTEPQLKK-- 458
+ VK +NT G + +PD P S +D ++N+ P
Sbjct: 537 YVEV------VK--------KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHEN 582
Query: 459 ----GSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGK--VGIFPKVFVE 512
G +AL++Y ++LE +E D+I V+ K ++ W G + G FP +V+
Sbjct: 583 IQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVK 642
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 219 PLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW- 277
P + Q A PPP + EI A+ + F +T EL + G+ V +LK+ + NW
Sbjct: 467 PEKAQPARPPPPAQPGEIGEAI------AKYNFNADTNVELSLRKGDRVILLKRVDQNWY 520
Query: 278 -ATVMFNGQKGLVPCNYLEPVELRIHPQQ---QPQEESSPQSDIPAPPSSKAPGRP 329
+ ++G+ P +Y+E V+ + P S SD SS P RP
Sbjct: 521 EGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRP 576
>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
sapiens]
Length = 492
Score = 56.6 bits (135), Expect = 5e-08
Identities = 66/304 (21%), Positives = 117/304 (38%), Gaps = 46/304 (15%)
Query: 252 VPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQPQ--- 308
V K+ + M I V K +D T M+N Y P + HP + Q
Sbjct: 10 VDRPKDWYKTMFKQIHMVHKPDDD---TDMYNTPYTYNAGLYNPPYSAQSHPAAKTQTYR 66
Query: 309 ------EESSPQS----DIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHY 358
++SP + P PP P P L P + E + T K
Sbjct: 67 PLSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDRSSTEKHDWDPPDRKVDTRKFRS 126
Query: 359 KYTVVMKTQPGL--------PYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPL----- 405
+ + + +PG P S + + + LE + ++ R + P
Sbjct: 127 EPRSIFEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPR 186
Query: 406 ---SEDSMKDAWGQVK--NYCLTLWCENTVGDQGFPDEPKESEKADANNQT------TEP 454
+ + + + G+V TL T P K+ E + + T + P
Sbjct: 187 GLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDMGRSAP 246
Query: 455 QLKKGSQ------VEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPK 508
+ ++G+ +A++ ++A ++L F++GD + +L K+++ W EGE G+VGIFP
Sbjct: 247 RERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPI 306
Query: 509 VFVE 512
+VE
Sbjct: 307 SYVE 310
Score = 52.0 bits (123), Expect = 1e-06
Identities = 67/300 (22%), Positives = 117/300 (39%), Gaps = 69/300 (23%)
Query: 227 PPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQK 286
P R TPE E + ++ F +T +EL G+ V++L+K + NW +G+
Sbjct: 246 PRERRGTPE----KEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRV 301
Query: 287 GLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKL 346
G+ P +Y+E + PP P RP P Q P E+
Sbjct: 302 GIFPISYVEKL---------------------TPPEKAQPARPP-PPAQ-----PGEIGE 334
Query: 347 SVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLS 406
++ Y + + L R ++ K+++ K+ R + P+S
Sbjct: 335 AI-------AKYNFNADTNVELSLRKGD-RVILLKRVDQNWYEGKIPGTNRQG--IFPVS 384
Query: 407 EDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEP-KESEKAD-----ANNQTTEPQLKK-- 458
+ VK +NT G + +PD P S +D ++N+ P
Sbjct: 385 YVEV------VK--------KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHEN 430
Query: 459 ----GSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGK--VGIFPKVFVE 512
G +AL++Y ++LE +E D+I V+ K ++ W G + G FP +V+
Sbjct: 431 IQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVK 490
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 219 PLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW- 277
P + Q A PPP + EI A+ + F +T EL + G+ V +LK+ + NW
Sbjct: 315 PEKAQPARPPPPAQPGEIGEAI------AKYNFNADTNVELSLRKGDRVILLKRVDQNWY 368
Query: 278 -ATVMFNGQKGLVPCNYLEPVELRIHPQQ---QPQEESSPQSDIPAPPSSKAPGRP 329
+ ++G+ P +Y+E V+ + P S SD SS P RP
Sbjct: 369 EGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRP 424
>gi|21450838 SH3 and cysteine rich domain 3 [Homo sapiens]
Length = 364
Score = 56.2 bits (134), Expect = 7e-08
Identities = 26/78 (33%), Positives = 45/78 (57%)
Query: 434 GFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEE 493
G P+ K++EK +++ +P ++ AL+ ++A + +DL+F G+ I V+ NEE
Sbjct: 224 GNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEE 283
Query: 494 WLEGECKGKVGIFPKVFV 511
W G+ KVG FP F+
Sbjct: 284 WWRGKIGEKVGFFPPNFI 301
>gi|47519798 neutrophil cytosolic factor 4 isoform 1 [Homo sapiens]
Length = 339
Score = 55.8 bits (133), Expect = 9e-08
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 461 QVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
+ EALF + +L F+ GD+I +LS++N++WLEG +G GIFP FV+
Sbjct: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
Score = 34.3 bits (77), Expect = 0.29
Identities = 14/48 (29%), Positives = 26/48 (54%)
Query: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
LF F +K EL G+++F+L + N +W G G+ P ++++
Sbjct: 178 LFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
>gi|163644267 neutrophil cytosolic factor 4 isoform 2 [Homo sapiens]
Length = 348
Score = 55.8 bits (133), Expect = 9e-08
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 461 QVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
+ EALF + +L F+ GD+I +LS++N++WLEG +G GIFP FV+
Sbjct: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
Score = 34.3 bits (77), Expect = 0.29
Identities = 14/48 (29%), Positives = 26/48 (54%)
Query: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
LF F +K EL G+++F+L + N +W G G+ P ++++
Sbjct: 178 LFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 55.1 bits (131), Expect = 2e-07
Identities = 62/275 (22%), Positives = 110/275 (40%), Gaps = 52/275 (18%)
Query: 247 VLFGFVPETKEELQVMPGNIV----FVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIH 302
VL G+ + ++EL + PG++V +V +G W F G+ GL P ++ +
Sbjct: 5 VLAGYRAQKEDELSLAPGDVVRQVRWVPARG---WLRGEFGGRYGLFPERLVQEIP---- 57
Query: 303 PQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKYTV 362
E + P ++ G P P ++ KV++ Y+
Sbjct: 58 ------ETLRGSGEARRPRCARRRGHPAKHPRPQR---------------WCKVNFSYSP 96
Query: 363 VMKTQPGLPYSQVRDMVSKKLE----LRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVK 418
+ L ++ +M+ K++E L ++ +L P + EL+ S+ +
Sbjct: 97 EQADELKLQAGEIVEMI-KEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNP----- 150
Query: 419 NYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEF 478
+ G PK S A + + LF Y+ P++L
Sbjct: 151 --------DMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELAL 202
Query: 479 QEGDIILVLSKVNEE--WLEGECKGKVGIFPKVFV 511
+ GD++ VLSK E+ W EGEC+G+ G+FP FV
Sbjct: 203 RRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 237
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 21/128 (16%)
Query: 246 RVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQ 305
+V F + PE +EL++ G IV ++K+ D W NGQ G P N++E ++
Sbjct: 89 KVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKNGQLGAFPSNFVELLD------- 141
Query: 306 QPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYK--YTVV 363
PPS P P +SPG ++ + + P Y V + Y V+
Sbjct: 142 ------------SGPPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVL 189
Query: 364 MKTQPGLP 371
QP P
Sbjct: 190 FDYQPEAP 197
Score = 42.7 bits (99), Expect = 8e-04
Identities = 17/47 (36%), Positives = 30/47 (63%)
Query: 466 FSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
FSY Q ++L+ Q G+I+ ++ ++ + W G+ G++G FP FVE
Sbjct: 92 FSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKNGQLGAFPSNFVE 138
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/150 (24%), Positives = 60/150 (40%), Gaps = 34/150 (22%)
Query: 219 PLQPQAAEPPPRP---------KTPEIFRALEG-EAHRVLFGFVPETKEELQVMPGNIVF 268
P P + P RP P+ + + E +RVLF + PE +EL + G++V
Sbjct: 150 PDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVK 209
Query: 269 VLKKGNDN--WATVMFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAP 326
VL K ++ W G++G+ P N++ +P PP K
Sbjct: 210 VLSKTTEDKGWWEGECQGRRGVFPDNFV----------------------LPPPPIKKLV 247
Query: 327 GRPQLSPGQKQKEEPKEVKLSVPMPYTLKV 356
R +S +EPK++ +P K+
Sbjct: 248 PRKVVSRESAPIKEPKKLMPKTSLPTVKKL 277
Score = 35.0 bits (79), Expect = 0.17
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 461 QVEALFSYEATQPEDLEFQEGDIILVLSKVNEE-WLEGECKGKVGIFPKVFVEDCATT 517
+V L Y A + ++L GD++ + V WL GE G+ G+FP+ V++ T
Sbjct: 2 EVLVLAGYRAQKEDELSLAPGDVVRQVRWVPARGWLRGEFGGRYGLFPERLVQEIPET 59
>gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]
Length = 740
Score = 55.1 bits (131), Expect = 2e-07
Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 11/86 (12%)
Query: 444 KADANNQTTEPQLKKGSQ--------VEALFSYEATQPEDLEFQEGDIILVLSKVNEE-- 493
++ ++ +TE +L GS V+AL+ YE ++L F EG II +L+K N++
Sbjct: 546 RSHTSSNSTEAELVSGSLNGDASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQDDD 605
Query: 494 -WLEGECKGKVGIFPKVFVEDCATTD 518
+ EGE G++G+FP V VE+ + ++
Sbjct: 606 GFWEGEFNGRIGVFPSVLVEELSASE 631
Score = 34.7 bits (78), Expect = 0.22
Identities = 15/52 (28%), Positives = 36/52 (69%), Gaps = 2/52 (3%)
Query: 463 EALFSYEATQPEDLEFQEGDIILVLSKVN-EEWLEGECK-GKVGIFPKVFVE 512
+ ++SY+A+QP++L +E +++ V+ + E+W++ K G+VG P+ +++
Sbjct: 475 KVVYSYKASQPDELTIEEHEVLEVIEDGDMEDWVKARNKVGQVGYVPEKYLQ 526
>gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo
sapiens]
Length = 342
Score = 54.7 bits (130), Expect = 2e-07
Identities = 27/58 (46%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Query: 456 LKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNE--EWLEGECKGKVGIFPKVFV 511
L + +V AL+S+E QP DL FQ GD I V+SK + +W EG+ +G+ GIFP +V
Sbjct: 282 LNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYV 339
>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
Length = 882
Score = 53.9 bits (128), Expect = 4e-07
Identities = 22/50 (44%), Positives = 34/50 (68%)
Query: 463 EALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
+AL+SYE +P DL+F +GDII++ KV+E+W GE G G P +++
Sbjct: 200 KALYSYEGKEPGDLKFNKGDIIVLRRKVDEQWYHGELHGTQGFLPASYIQ 249
Score = 49.7 bits (117), Expect = 7e-06
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 10/80 (12%)
Query: 218 APLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW 277
APL A P P+ L E +RV+ + P+++ E+++ G+IVFV KK D W
Sbjct: 809 APLSMAAIRPEPK--------LLPRERYRVVVSYPPQSEAEIELKEGDIVFVHKKREDGW 860
Query: 278 --ATVMFNGQKGLVPCNYLE 295
T+ NG+ GL P +++E
Sbjct: 861 YKGTLQRNGRTGLFPGSFVE 880
Score = 42.7 bits (99), Expect = 8e-04
Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%)
Query: 450 QTTEPQLKKGSQVEALFSYEATQPED----LEFQEGDIILVLSKVNEEWLEGECKGKVGI 505
Q +P Q +AL+ +E + L F + +I+ VL +V+E W EG K+GI
Sbjct: 249 QCIQPLPHAPPQGKALYDFEMKDKDQDKDCLTFTKDEILTVLRRVDENWAEGMLGDKIGI 308
Query: 506 FPKVFVE 512
FP ++VE
Sbjct: 309 FPLLYVE 315
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Query: 453 EPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEG--ECKGKVGIFPKVF 510
EP+L + + SY ++E +EGDI+ V K + W +G + G+ G+FP F
Sbjct: 819 EPKLLPRERYRVVVSYPPQSEAEIELKEGDIVFVHKKREDGWYKGTLQRNGRTGLFPGSF 878
Query: 511 VE 512
VE
Sbjct: 879 VE 880
Score = 40.0 bits (92), Expect = 0.005
Identities = 75/358 (20%), Positives = 134/358 (37%), Gaps = 50/358 (13%)
Query: 174 PVVIPVGK-LFRPNERQVAQLAKKDYLGKATVVASVVDQDSF-------SGFAPLQP-QA 224
P ++P GK L+ ++ L K G V+ VD+ + GF P Q
Sbjct: 193 PCLLPYGKALYSYEGKEPGDL--KFNKGDIIVLRRKVDEQWYHGELHGTQGFLPASYIQC 250
Query: 225 AEP----PPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATV 280
+P PP+ K F + + + F TK+E I+ VL++ ++NWA
Sbjct: 251 IQPLPHAPPQGKALYDFEMKDKDQDKDCLTF---TKDE-------ILTVLRRVDENWAEG 300
Query: 281 MFNGQKGLVPCNYLE----PVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQK 336
M + G+ P Y+E +L + P SS + +P+ + A P SP
Sbjct: 301 MLGDKIGIFPLLYVELNDSAKQLIEMDKPCPAAASSCNASLPSDSGAVASVAP--SPTLS 358
Query: 337 QKEEPKEVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRP 396
+ V K + +T + T + R +E+ S P
Sbjct: 359 SSGAVSAFQRRVDGKKNTKKRHSFTALSVTHRSSQAASHRH----SMEISAPVLISSSDP 414
Query: 397 RDSNELVPLSEDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQL 456
R + + G + + ++ G + + Q T P++
Sbjct: 415 RAAARI------------GDLAHLSCAAPTQDVSSSAGSTPTAVPRAASVSGEQGTPPKV 462
Query: 457 KKGSQVE-ALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGEC--KGKVGIFPKVFV 511
+ V AL++Y+ + ++LE +G++ VL K + W +G G G+FP +V
Sbjct: 463 QLPLNVYLALYAYKPQKSDELELHKGEMYRVLEKCQDGWFKGASLRTGVSGVFPGNYV 520
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 4/102 (3%)
Query: 199 LGKATVVASVVDQDSFSGFAPLQ-PQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKE 257
L + A D S +G P P+AA TP + L + L+ + P+ +
Sbjct: 423 LAHLSCAAPTQDVSSSAGSTPTAVPRAASVSGEQGTPPKVQ-LPLNVYLALYAYKPQKSD 481
Query: 258 ELQVMPGNIVFVLKKGNDNW--ATVMFNGQKGLVPCNYLEPV 297
EL++ G + VL+K D W + G G+ P NY+ PV
Sbjct: 482 ELELHKGEMYRVLEKCQDGWFKGASLRTGVSGVFPGNYVTPV 523
>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
sapiens]
Length = 1004
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/91 (29%), Positives = 55/91 (60%), Gaps = 10/91 (10%)
Query: 432 DQGFPDEPKESEKADANNQT----TEPQLKKGSQ------VEALFSYEATQPEDLEFQEG 481
D+G + +ES ++ ++ T + P+ ++G+ +A++ ++A ++L F++G
Sbjct: 732 DRGGALQDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKG 791
Query: 482 DIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
D + +L K+++ W EGE G+VGIFP +VE
Sbjct: 792 DTVYILRKIDQNWYEGEHHGRVGIFPISYVE 822
Score = 52.0 bits (123), Expect = 1e-06
Identities = 67/300 (22%), Positives = 117/300 (39%), Gaps = 69/300 (23%)
Query: 227 PPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQK 286
P R TPE E + ++ F +T +EL G+ V++L+K + NW +G+
Sbjct: 758 PRERRGTPE----KEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRV 813
Query: 287 GLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKL 346
G+ P +Y+E + PP P RP P Q P E+
Sbjct: 814 GIFPISYVEKL---------------------TPPEKAQPARPP-PPAQ-----PGEIGE 846
Query: 347 SVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLS 406
++ Y + + L R ++ K+++ K+ R + P+S
Sbjct: 847 AI-------AKYNFNADTNVELSLRKGD-RVILLKRVDQNWYEGKIPGTNRQG--IFPVS 896
Query: 407 EDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEP-KESEKAD-----ANNQTTEPQLKK-- 458
+ VK +NT G + +PD P S +D ++N+ P
Sbjct: 897 YVEV------VK--------KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHEN 942
Query: 459 ----GSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGK--VGIFPKVFVE 512
G +AL++Y ++LE +E D+I V+ K ++ W G + G FP +V+
Sbjct: 943 IQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVK 1002
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 219 PLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW- 277
P + Q A PPP + EI A+ + F +T EL + G+ V +LK+ + NW
Sbjct: 827 PEKAQPARPPPPAQPGEIGEAI------AKYNFNADTNVELSLRKGDRVILLKRVDQNWY 880
Query: 278 -ATVMFNGQKGLVPCNYLEPVELRIHPQQ---QPQEESSPQSDIPAPPSSKAPGRP 329
+ ++G+ P +Y+E V+ + P S SD SS P RP
Sbjct: 881 EGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRP 936
>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
sapiens]
Length = 1100
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/91 (29%), Positives = 55/91 (60%), Gaps = 10/91 (10%)
Query: 432 DQGFPDEPKESEKADANNQT----TEPQLKKGSQ------VEALFSYEATQPEDLEFQEG 481
D+G + +ES ++ ++ T + P+ ++G+ +A++ ++A ++L F++G
Sbjct: 828 DRGGALQDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKG 887
Query: 482 DIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
D + +L K+++ W EGE G+VGIFP +VE
Sbjct: 888 DTVYILRKIDQNWYEGEHHGRVGIFPISYVE 918
Score = 52.0 bits (123), Expect = 1e-06
Identities = 67/300 (22%), Positives = 117/300 (39%), Gaps = 69/300 (23%)
Query: 227 PPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQK 286
P R TPE E + ++ F +T +EL G+ V++L+K + NW +G+
Sbjct: 854 PRERRGTPE----KEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRV 909
Query: 287 GLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKL 346
G+ P +Y+E + PP P RP P Q P E+
Sbjct: 910 GIFPISYVEKL---------------------TPPEKAQPARPP-PPAQ-----PGEIGE 942
Query: 347 SVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLS 406
++ Y + + L R ++ K+++ K+ R + P+S
Sbjct: 943 AI-------AKYNFNADTNVELSLRKGD-RVILLKRVDQNWYEGKIPGTNRQG--IFPVS 992
Query: 407 EDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEP-KESEKAD-----ANNQTTEPQLKK-- 458
+ VK +NT G + +PD P S +D ++N+ P
Sbjct: 993 YVEV------VK--------KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHEN 1038
Query: 459 ----GSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGK--VGIFPKVFVE 512
G +AL++Y ++LE +E D+I V+ K ++ W G + G FP +V+
Sbjct: 1039 IQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVK 1098
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 219 PLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW- 277
P + Q A PPP + EI A+ + F +T EL + G+ V +LK+ + NW
Sbjct: 923 PEKAQPARPPPPAQPGEIGEAI------AKYNFNADTNVELSLRKGDRVILLKRVDQNWY 976
Query: 278 -ATVMFNGQKGLVPCNYLEPVELRIHPQQ---QPQEESSPQSDIPAPPSSKAPGRP 329
+ ++G+ P +Y+E V+ + P S SD SS P RP
Sbjct: 977 EGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRP 1032
>gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]
Length = 888
Score = 53.5 bits (127), Expect = 5e-07
Identities = 23/50 (46%), Positives = 34/50 (68%)
Query: 463 EALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
+AL++YE +P DL+F +GDII++ +V+E W GE G G FP FV+
Sbjct: 140 KALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQ 189
Score = 52.4 bits (124), Expect = 1e-06
Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 10/104 (9%)
Query: 204 VVASVVDQDSFSGFAPLQPQAAE--PPPRPKTPEI------FRALEGEAHRVLFGFVPET 255
V + + QD+F A A PPPR + R + E HRV+ + P++
Sbjct: 785 VAGAALAQDAFHRKASSLDSAVPIAPPPRQACSSLGPVLNESRPVVCERHRVVVSYPPQS 844
Query: 256 KEELQVMPGNIVFVLKKGNDNW--ATVMFNGQKGLVPCNYLEPV 297
+ EL++ G+IVFV KK D W T+ NG+ GL P +++E +
Sbjct: 845 EAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI 888
Score = 43.9 bits (102), Expect = 4e-04
Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%)
Query: 450 QTTEPQLKKGSQVEALFSYEATQPED----LEFQEGDIILVLSKVNEEWLEGECKGKVGI 505
Q +P + Q +AL+ +E E L F + D++ V+ +V+E W EG K+GI
Sbjct: 189 QIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGI 248
Query: 506 FPKVFVE 512
FP +VE
Sbjct: 249 FPISYVE 255
Score = 40.4 bits (93), Expect = 0.004
Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 467 SYEATQPEDLEFQEGDIILVLSKVNEEWLEG--ECKGKVGIFPKVFVED 513
SY +LE +EGDI+ V K + W +G + GK G+FP FVE+
Sbjct: 839 SYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVEN 887
Score = 35.8 bits (81), Expect = 0.099
Identities = 34/157 (21%), Positives = 62/157 (39%), Gaps = 15/157 (9%)
Query: 230 RPKT-PEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW--ATVMFNGQK 286
RP+T P ++ A+ + + P ++EL++ G + V ++ D W T M +
Sbjct: 442 RPQTRPSVYVAI--------YPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKI 493
Query: 287 GLVPCNYLEPVELRIHPQQQPQEESSPQSD----IPAPPSSKAPGRPQLSPGQKQKEEPK 342
G+ P NY+ PV + Q + S + S A G Q G P
Sbjct: 494 GVFPGNYVAPVTRAVTNASQAKVPMSTAGQTSRGVTMVSPSTAGGPAQKLQGNGVAGSPS 553
Query: 343 EVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMV 379
V +V ++ + V++ + +Q R+ V
Sbjct: 554 VVPAAVVSAAHIQTSPQAKVLLHMTGQMTVNQARNAV 590
Score = 35.4 bits (80), Expect = 0.13
Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 3/60 (5%)
Query: 454 PQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGEC--KGKVGIFPKVFV 511
PQ + V A++ Y + ++LE ++G++ LV + + W +G K+G+FP +V
Sbjct: 443 PQTRPSVYV-AIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYV 501
Score = 33.9 bits (76), Expect = 0.38
Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 15/131 (11%)
Query: 215 SGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGN 274
+ F + +PPP+ K F + EA + F + +++ V+++ +
Sbjct: 185 TNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKD----------DVLTVIRRVD 234
Query: 275 DNWATVMFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPG 334
+NWA M + G+ P +Y VE +Q + + P + A S A + +P
Sbjct: 235 ENWAEGMLADKIGIFPISY---VEFNSAAKQLIEWDKPPVPGVDAGECSSAAAQSSTAP- 290
Query: 335 QKQKEEPKEVK 345
K + K K
Sbjct: 291 -KHSDTKKNTK 300
Score = 33.1 bits (74), Expect = 0.64
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Query: 201 KATVVASVVDQDSFSGFAPLQP--QAAEPPPR--PKTPEIFRALEGEAHRVLFGFVPETK 256
+++ VA+ +D S QP Q+ PP R P+ P + L+ + +
Sbjct: 100 QSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLP---------CAKALYNYEGKEP 150
Query: 257 EELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQPQ 308
+L+ G+I+ + ++ ++NW NG G P N+++ + + PQ PQ
Sbjct: 151 GDLKFSKGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQII--KPLPQPPPQ 200
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,794,072
Number of Sequences: 37866
Number of extensions: 1088635
Number of successful extensions: 8108
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 205
Number of HSP's successfully gapped in prelim test: 179
Number of HSP's that attempted gapping in prelim test: 6969
Number of HSP's gapped (non-prelim): 1241
length of query: 526
length of database: 18,247,518
effective HSP length: 107
effective length of query: 419
effective length of database: 14,195,856
effective search space: 5948063664
effective search space used: 5948063664
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.