BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|189011559 B-cell scaffold protein with ankyrin repeats 1 isoform 3 [Homo sapiens] (652 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|189011559 B-cell scaffold protein with ankyrin repeats 1 isof... 1345 0.0 gi|144953889 B-cell scaffold protein with ankyrin repeats 1 isof... 1294 0.0 gi|144953891 B-cell scaffold protein with ankyrin repeats 1 isof... 1294 0.0 gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo sa... 149 8e-36 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 47 4e-05 gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 45 2e-04 gi|13375654 PTIP-associated 1 protein [Homo sapiens] 44 5e-04 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 42 0.002 gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens] 42 0.002 gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens] 42 0.002 gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 41 0.003 gi|210032580 SET domain containing 1B [Homo sapiens] 40 0.007 gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 40 0.009 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.012 gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 39 0.015 gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 39 0.015 gi|14277690 hypothetical protein LOC9750 isoform 2 [Homo sapiens] 39 0.015 gi|164414421 hypothetical protein LOC9750 isoform 1 [Homo sapiens] 39 0.015 gi|55741655 anoctamin 8 [Homo sapiens] 39 0.020 gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 39 0.020 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 39 0.020 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 39 0.020 gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens] 38 0.026 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 38 0.026 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 38 0.026 gi|209862789 microtubule associated monoxygenase, calponin and L... 37 0.044 gi|50726968 microfibrillar-associated protein 1 [Homo sapiens] 37 0.044 gi|17975763 myelin transcription factor 1 [Homo sapiens] 37 0.057 gi|118600967 shroom family member 4 [Homo sapiens] 37 0.075 gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 37 0.075 >gi|189011559 B-cell scaffold protein with ankyrin repeats 1 isoform 3 [Homo sapiens] Length = 652 Score = 1345 bits (3481), Expect = 0.0 Identities = 652/652 (100%), Positives = 652/652 (100%) Query: 1 MLPAAPGKGLGSPDPAPCGPAPPDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRN 60 MLPAAPGKGLGSPDPAPCGPAPPDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRN Sbjct: 1 MLPAAPGKGLGSPDPAPCGPAPPDSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRN 60 Query: 61 TIPLAVVLPTEIPCENPGEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKA 120 TIPLAVVLPTEIPCENPGEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKA Sbjct: 61 TIPLAVVLPTEIPCENPGEIFIILRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKA 120 Query: 121 LEFPAGSVHVNVYCDGIVKATTKIKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTS 180 LEFPAGSVHVNVYCDGIVKATTKIKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTS Sbjct: 121 LEFPAGSVHVNVYCDGIVKATTKIKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTS 180 Query: 181 IFKHEIPYYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASK 240 IFKHEIPYYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASK Sbjct: 181 IFKHEIPYYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASK 240 Query: 241 MKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNP 300 MKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNP Sbjct: 241 MKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNP 300 Query: 301 AFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPG 360 AFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPG Sbjct: 301 AFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPG 360 Query: 361 ADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQE 420 ADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQE Sbjct: 361 ADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQE 420 Query: 421 TGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPA 480 TGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPA Sbjct: 421 TGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPA 480 Query: 481 PTPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCL 540 PTPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCL Sbjct: 481 PTPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCL 540 Query: 541 TDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEE 600 TDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEE Sbjct: 541 TDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEE 600 Query: 601 ENVYNKLTIVHHPGGKETAHNENKFYNVHFSNKLPARPQVEKEFGFCCKKDH 652 ENVYNKLTIVHHPGGKETAHNENKFYNVHFSNKLPARPQVEKEFGFCCKKDH Sbjct: 601 ENVYNKLTIVHHPGGKETAHNENKFYNVHFSNKLPARPQVEKEFGFCCKKDH 652 >gi|144953889 B-cell scaffold protein with ankyrin repeats 1 isoform 2 [Homo sapiens] Length = 755 Score = 1294 bits (3348), Expect = 0.0 Identities = 629/629 (100%), Positives = 629/629 (100%) Query: 24 DSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENPGEIFII 83 DSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENPGEIFII Sbjct: 127 DSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENPGEIFII 186 Query: 84 LRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTK 143 LRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTK Sbjct: 187 LRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTK 246 Query: 144 IKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNK 203 IKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNK Sbjct: 247 IKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNK 306 Query: 204 YTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKK 263 YTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKK Sbjct: 307 YTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKK 366 Query: 264 IFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEME 323 IFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEME Sbjct: 367 IFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEME 426 Query: 324 GEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRP 383 GEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRP Sbjct: 427 GEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRP 486 Query: 384 VANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEED 443 VANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEED Sbjct: 487 VANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEED 546 Query: 444 PYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQ 503 PYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQ Sbjct: 547 PYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQ 606 Query: 504 QKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDE 563 QKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDE Sbjct: 607 QKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDE 666 Query: 564 ALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEEENVYNKLTIVHHPGGKETAHNEN 623 ALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEEENVYNKLTIVHHPGGKETAHNEN Sbjct: 667 ALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEEENVYNKLTIVHHPGGKETAHNEN 726 Query: 624 KFYNVHFSNKLPARPQVEKEFGFCCKKDH 652 KFYNVHFSNKLPARPQVEKEFGFCCKKDH Sbjct: 727 KFYNVHFSNKLPARPQVEKEFGFCCKKDH 755 >gi|144953891 B-cell scaffold protein with ankyrin repeats 1 isoform 1 [Homo sapiens] Length = 785 Score = 1294 bits (3348), Expect = 0.0 Identities = 629/629 (100%), Positives = 629/629 (100%) Query: 24 DSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENPGEIFII 83 DSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENPGEIFII Sbjct: 157 DSEDYFEVNIPTDLRAKHSGEISERKEIEELSEASRNTIPLAVVLPTEIPCENPGEIFII 216 Query: 84 LRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTK 143 LRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTK Sbjct: 217 LRDEVIGDTVEVEFTSSNKRIRTRPALWNKKVWCMKALEFPAGSVHVNVYCDGIVKATTK 276 Query: 144 IKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNK 203 IKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNK Sbjct: 277 IKYYPTAKAKECLFRMADSGESLCQNSIEELDGVLTSIFKHEIPYYEFQSLQTEICSQNK 336 Query: 204 YTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKK 263 YTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKK Sbjct: 337 YTHFKELPTLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKK 396 Query: 264 IFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEME 323 IFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEME Sbjct: 397 IFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEME 456 Query: 324 GEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRP 383 GEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRP Sbjct: 457 GEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRP 516 Query: 384 VANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEED 443 VANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEED Sbjct: 517 VANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEED 576 Query: 444 PYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQ 503 PYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQ Sbjct: 577 PYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQ 636 Query: 504 QKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDE 563 QKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDE Sbjct: 637 QKTARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDE 696 Query: 564 ALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEEENVYNKLTIVHHPGGKETAHNEN 623 ALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEEENVYNKLTIVHHPGGKETAHNEN Sbjct: 697 ALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKRPEEENVYNKLTIVHHPGGKETAHNEN 756 Query: 624 KFYNVHFSNKLPARPQVEKEFGFCCKKDH 652 KFYNVHFSNKLPARPQVEKEFGFCCKKDH Sbjct: 757 KFYNVHFSNKLPARPQVEKEFGFCCKKDH 785 Score = 55.8 bits (133), Expect = 1e-07 Identities = 23/23 (100%), Positives = 23/23 (100%) Query: 1 MLPAAPGKGLGSPDPAPCGPAPP 23 MLPAAPGKGLGSPDPAPCGPAPP Sbjct: 1 MLPAAPGKGLGSPDPAPCGPAPP 23 >gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo sapiens] Length = 805 Score = 149 bits (376), Expect = 8e-36 Identities = 151/565 (26%), Positives = 239/565 (42%), Gaps = 104/565 (18%) Query: 64 LAVVLPTEIPCENPGEIFIILRDEVIGDTV--EVEFTSSNK-RIRTRPALWNKKVWCMKA 120 L VV P I C +++I+R + + D V E EF+ + +R + N+ +KA Sbjct: 178 LMVVQPDRIRCGAETTVYVIVRCK-LDDRVATEAEFSPEDSPSVRMEAKVENEYTISVKA 236 Query: 121 LEFPAGSVHVNVYCDGIVKATTKIKYYPTAKA-KECLFRMADSGESLCQN------SIEE 173 +G+V + +Y +V T I YY + L A+ E +CQ + E Sbjct: 237 PNLSSGNVSLKIYSGDLVVCETVISYYTDMEEIGNLLSNAANPVEFMCQAFKIVPYNTET 296 Query: 174 LDGVLTSIFKHEIP-----YYEFQSLQTEICSQNKYTHFKELPTLLHCAAKFGLKNLAIH 228 LD +LT K+ IP + L+ E N+ +ELPTLLH AAK+GLKNL Sbjct: 297 LDKLLTESLKNNIPASGLHLFGINQLEEEDMMTNQRD--EELPTLLHFAAKYGLKNLTAL 354 Query: 229 LLQCSGATWASKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIA 288 LL C GA A + N G P IAE+HG ++L++ +++ ++ +D+ Sbjct: 355 LLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEY-VETVDMLKS---------- 403 Query: 289 SFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSE 348 H + +G+ AD E + S L G + E Sbjct: 404 --------------HIKEELMHGEEADAVY------ESMAHLSTDLLMKCSLNPGCD--E 441 Query: 349 DQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMER 408 D Y+ + F+P A + + S+ P+P + F Sbjct: 442 DLYESMAAFVPAATEDLYVEMLQASTSNPIP-----GDGF-------------------- 476 Query: 409 SQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKT 468 S+ +R+ G + ++ +EED Y + DD + + LA+ Sbjct: 477 SRATKDSMIRKFLEGNSMGMTNLERDQCHLGQEEDVYHTVD-DDEAFSVDLAS------- 528 Query: 469 GSRSFIINRPPAPTPRPTSIPPKE----ETTPYIAQVFQQKTARRQ-----SDDDKFCGL 519 RPP P PRP + P + PYI +VF +K+ R S + G Sbjct: 529 --------RPPVPVPRPETTAPGAHQLPDNEPYIFKVFAEKSQERPGNFYVSSESIRKGP 580 Query: 520 PKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMG---KS 576 P + R R +S + G T GQ +LI LQE+VK G +++DEA+ FK WQ+ +S Sbjct: 581 PVRPWRDRPQSSIYDPFAGMKTPGQRQLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRS 640 Query: 577 GLEMIQQEKLRQLRDCIIGKRPEEE 601 QQE L++LRD I ++ E++ Sbjct: 641 ESFRFQQENLKRLRDSITRRQREKQ 665 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 47.4 bits (111), Expect = 4e-05 Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 16/88 (18%) Query: 376 PPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQE--------TGDEPKG 427 PP PPP PV L P GT G G P + ++ + +E + Sbjct: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPGGG--------GPPALEEDLTVININSSDEEEEE 892 Query: 428 EKEKKEEEKEQEEEEDPYTFAEIDDSEY 455 E+E++EEE+E+EEEE+ + E D+ EY Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEY 920 Score = 37.4 bits (85), Expect = 0.044 Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 15/74 (20%) Query: 419 QETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRP 478 +E +E +GE E++EEE+++EEEE+ E++D E+ T P Sbjct: 932 EEEFEEEEGELEEEEEEEDEEEEEE---LEEVEDLEFG-----------TAGGEVEEGAP 977 Query: 479 PAPTPRPTSIPPKE 492 P PT P ++PP E Sbjct: 978 PPPT-LPPALPPPE 990 >gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] Length = 1163 Score = 45.4 bits (106), Expect = 2e-04 Identities = 69/331 (20%), Positives = 127/331 (38%), Gaps = 94/331 (28%) Query: 248 DPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDI-ASFSTYIPSTQNPAFHHES 306 +P+ + H K + K ++ +++ +++D E+D + P + + HH S Sbjct: 366 NPSKTSNGHQSKSMLK-------DDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNS 418 Query: 307 RKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENN 366 + AD + + G ++ SG +++ SESS ++ Sbjct: 419 -----EGADNSRDDSSSHSGSESSSGSDSE-------SESSSS--------------DSE 452 Query: 367 SQEPLMSSRP-PLPPPRPVANAFQLER------PHFTLPGTMVEGQMERSQNWGHPGVRQ 419 + EP S+ P P PPP N +QL+ PH P + V+ + SQ + G Q Sbjct: 453 ANEPSQSASPEPEPPP---TNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQ 509 Query: 420 ETGD---EPKGEKE-----------------------------------------KKEEE 435 TG+ + G KE K+ ++ Sbjct: 510 GTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKK 569 Query: 436 KEQEEEEDPYTFAEID-DSEYDMILANLSIKKKT---GSRSFIINRPPAPTPRPTSIPPK 491 E+ E+P +I+ ++ D+ + S + K GSR I + +PRPT+ K Sbjct: 570 AEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKK 629 Query: 492 EETTPYIAQVFQQ--KTARRQSDDDKFCGLP 520 ++T +Q ++ +T SD D+ LP Sbjct: 630 YKSTSKSSQKSREIIETDTSSSDSDESESLP 660 >gi|13375654 PTIP-associated 1 protein [Homo sapiens] Length = 254 Score = 43.9 bits (102), Expect = 5e-04 Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 23/146 (15%) Query: 308 KTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNS 367 K + G E E EG G + G P G E +E+ +D V P +D E Sbjct: 45 KAEDEGEGGREETEREGSGGEEAQG----EVPSAGGEEPAEEDSEDWCV--PCSDEE--- 95 Query: 368 QEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKG 427 E +P +PPP + ++L H TL E Q E R+ E + Sbjct: 96 VELPADGQPWMPPPSEIQRLYELLAAHGTL-----ELQAEILP-------RRPPTPEAQS 143 Query: 428 EKEKKEEEKE--QEEEEDPYTFAEID 451 E+E+ +EE E +EEEE P+ E D Sbjct: 144 EEERSDEEPEAKEEEEEKPHMPTEFD 169 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 42.0 bits (97), Expect = 0.002 Identities = 66/302 (21%), Positives = 116/302 (38%), Gaps = 58/302 (19%) Query: 271 QEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNG 330 +E N E+ D E+ IA+ + G+ E +E+ EG Sbjct: 401 EEFTANEEEAEDEEDTIAA----------------EEQLEGEVDHAMELSELAREG---- 440 Query: 331 SGMETKHSPLEVGSESSEDQYDDLYVFIPGA-DPENNSQEPLMSSRPPLPPPRPVANAFQ 389 E+ E QY Y PG+ E+ ++ + ++ P PV + Sbjct: 441 ----------ELSMEELLQQYAGAYA--PGSGSSEDEDEDEVDANSSDCEPEGPV----E 484 Query: 390 LERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAE 449 E P + + +RS++ +E E G +E E E+ E+ + A+ Sbjct: 485 AEEPPQEDSSSQSDSVEDRSEDEEDEHSEEE---ETSGSSASEESESEESEDAQSQSQAD 541 Query: 450 IDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTARR 509 ++ + D + L + + S + + P PTP PT++ PK+E T A Sbjct: 542 EEEEDDDFGVEYLLARDEEQSEADAGSGP--PTPGPTTLGPKKEITDI--------AAAA 591 Query: 510 QSDDDKFCGLPKKQDRARIESPAFSTLRGCLTD----GQEELILLQEKVKNGKMSMDEAL 565 +S K L Q +++P LRG L + G + L+ + EK NG ++ + L Sbjct: 592 ESLQPKGYTLATTQ----VKTPIPLLLRGQLREYQHIGLDWLVTMYEKKLNGILADEMGL 647 Query: 566 EK 567 K Sbjct: 648 GK 649 Score = 34.7 bits (78), Expect = 0.28 Identities = 37/171 (21%), Positives = 72/171 (42%), Gaps = 26/171 (15%) Query: 420 ETGD-EPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSF---II 475 E GD +P+ ++E+ +EE + EE+ AE E +++ + + RS ++ Sbjct: 285 EDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLL 344 Query: 476 NRPPAPTPRPTSIPP---------KEETTPYIAQVFQQKTARRQ---------SDDDKFC 517 P +P+ P+S EE P + ++ +A Q DD++F Sbjct: 345 EGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFT 404 Query: 518 GLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKF 568 ++ + A L G + E L E + G++SM+E L+++ Sbjct: 405 ANEEEAEDEEDTIAAEEQLEGEVDHAME----LSELAREGELSMEELLQQY 451 >gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens] Length = 2817 Score = 41.6 bits (96), Expect = 0.002 Identities = 57/239 (23%), Positives = 93/239 (38%), Gaps = 23/239 (9%) Query: 212 TLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQ 271 TL+H A + GL L LLQ G A + N EG+ P +A G+ +L ++ Sbjct: 166 TLMHFAVRLGLLRLTWFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLL------ 219 Query: 272 EIDINNEQENDYEEDI-ASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNG 330 +EN E D +S S IP HH Y +++ +E G Sbjct: 220 ------TEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGDGCT 273 Query: 331 SGMETKHSPLEVGSESSEDQYDDLYVFI-----PGADPENNSQEPLMSSRPPLPPPRPVA 385 + + + +++ Q D L + P + PE + Q + P P+ ++ Sbjct: 274 GPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQ--FLPCAPEPTDPQRLS 331 Query: 386 NAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDP 444 ++ + E PG+ V Q E + V +E D +K K E K +E E P Sbjct: 332 SSEETESTQ-CCPGSPV-AQTESPCDLSSI-VEEENTDRSCRKKNKGVERKGEEVEPAP 387 >gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens] Length = 2813 Score = 41.6 bits (96), Expect = 0.002 Identities = 57/239 (23%), Positives = 93/239 (38%), Gaps = 23/239 (9%) Query: 212 TLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQ 271 TL+H A + GL L LLQ G A + N EG+ P +A G+ +L ++ Sbjct: 166 TLMHFAVRLGLLRLTWFLLQKPGGRGALSIHNQEGATPVSLALERGYHKLHQLL------ 219 Query: 272 EIDINNEQENDYEEDI-ASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNG 330 +EN E D +S S IP HH Y +++ +E G Sbjct: 220 ------TEENAGEPDSWSSLSYEIPYGDCSVRHHRELDIYTLTSESDSHHEHPFPGDGCT 273 Query: 331 SGMETKHSPLEVGSESSEDQYDDLYVFI-----PGADPENNSQEPLMSSRPPLPPPRPVA 385 + + + +++ Q D L + P + PE + Q + P P+ ++ Sbjct: 274 GPIFKLMNIQQQLMKTNLKQMDSLMPLMMTAQDPSSAPETDGQ--FLPCAPEPTDPQRLS 331 Query: 386 NAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDP 444 ++ + E PG+ V Q E + V +E D +K K E K +E E P Sbjct: 332 SSEETESTQ-CCPGSPV-AQTESPCDLSSI-VEEENTDRSCRKKNKGVERKGEEVEPAP 387 >gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] Length = 1312 Score = 41.2 bits (95), Expect = 0.003 Identities = 42/157 (26%), Positives = 61/157 (38%), Gaps = 7/157 (4%) Query: 359 PGADPENNSQEPLMSSRPPLPPPRPVANAFQLERP-HFTLPGTMVEGQMERSQNWGHP-- 415 P P ++S P PP PP P A F + P H T E+ + P Sbjct: 197 PSPSPSSSSPSPPPPPPPPAPPAPP-APRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTG 255 Query: 416 GVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDD--SEYDMILANLSIKKKTGSRSF 473 + P E+E++EEE+E+EEEED + S LA + + S+ F Sbjct: 256 SNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGI-YDDNSLSQDF 314 Query: 474 IINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTARRQ 510 + P P +PT P T P + RR+ Sbjct: 315 PGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRR 351 Score = 35.8 bits (81), Expect = 0.13 Identities = 41/199 (20%), Positives = 76/199 (38%), Gaps = 17/199 (8%) Query: 305 ESRKTYGQSADGAEANEMEGEGKQNGSG--METKHSPLEVGSESSEDQYDDLYVFIPGAD 362 +++ T G++ ++ G GSG + K S + S+++ + GA+ Sbjct: 910 KTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTK---------GAE 960 Query: 363 PENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETG 422 + S E + P PPP+ L T+ + ++ G Sbjct: 961 ETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGG 1020 Query: 423 DEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLS------IKKKTGSRSFIIN 476 E + E+E++EEE+E+EEE+ P T + A + + G S + Sbjct: 1021 AEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQ 1080 Query: 477 RPPAPTPRPTSIPPKEETT 495 P P P P ++P + T Sbjct: 1081 LPTLPPPMPWNLPAGVDCT 1099 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 40.0 bits (92), Expect = 0.007 Identities = 52/238 (21%), Positives = 86/238 (36%), Gaps = 24/238 (10%) Query: 266 EDFSIQEIDINNEQENDYEEDI------ASFSTYIPSTQNPAFHHESRKTYGQSADGAEA 319 ED ++ E +E ++D EE + A ++ S+++ F S + S D E Sbjct: 1079 EDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEV 1138 Query: 320 NEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDD--LYVFIPGADPENNSQEPLMSSRPP 377 E E ++ M + S G E E ++ L P D +E + + Sbjct: 1139 VAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAV 1198 Query: 378 LPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKE 437 P RP L+ P + VE + + PG+ QE E KE E Sbjct: 1199 APEERPS----MLDEPPLPVG---VEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEAR 1251 Query: 438 QEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETT 495 + +++ ++ L ++ PP PRP S PP+ ETT Sbjct: 1252 PPLSPERAPEHDLEVEPEPPMMLPLPLQPPL---------PPPRPPRPPSPPPEPETT 1300 >gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sapiens] Length = 1925 Score = 39.7 bits (91), Expect = 0.009 Identities = 39/139 (28%), Positives = 64/139 (46%), Gaps = 19/139 (13%) Query: 414 HPGV-RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRS 472 +PG+ ++E G+E KGE+E++E E+E+EEEE+ E+ E + K++ S + Sbjct: 1754 YPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEE-EELGKEEIEEKEEERDEKEEKVSWA 1812 Query: 473 FIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFCGLPKKQDRARIESPA 532 I PTP+P S +E Q Q D+K A PA Sbjct: 1813 GI-----GPTPQPES---QESMQWQWQQQLNVMVKEEQEQDEK---------EAIRRLPA 1855 Query: 533 FSTLRGCLTDGQEELILLQ 551 F+ L+ L + + IL++ Sbjct: 1856 FANLQEALLENMIQNILVE 1874 Score = 30.0 bits (66), Expect = 7.0 Identities = 15/52 (28%), Positives = 31/52 (59%) Query: 399 GTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEI 450 G +G+ E + +ET +E G++E +E+E+E++E+E+ ++A I Sbjct: 1763 GEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGI 1814 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 39.3 bits (90), Expect = 0.012 Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 26/199 (13%) Query: 403 EGQMERSQNWGHPGVRQETGDEP-------------KGEKEKKEEEKEQEEEEDPYTFAE 449 +GQ + +N PG E+G+E K EK+++E +K EE+ E Sbjct: 198 KGQKKNQKN--KPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKE 255 Query: 450 IDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEE---TTPYIAQVFQQKT 506 ++ E K+K R F + T + P E TP A+ + Sbjct: 256 KEELETG---KKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAE-DDNEG 311 Query: 507 ARRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALE 566 +++ D K G +++++ + + P+ +T++ QE L L+E+ + K +E ++ Sbjct: 312 DKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAM----QEALAKLKEEEERQKREEEERIK 367 Query: 567 KFKHWQMGKSGLEMIQQEK 585 + + + + E ++QEK Sbjct: 368 RLEELEAKRKEEERLEQEK 386 Score = 31.2 bits (69), Expect = 3.1 Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Query: 417 VRQETGDEPKGEKEKKEEEKEQEE-EEDPYTFAEIDDSEYDMILANLSIKKKTG 469 V E + P+ E+E++EEE+E EE EE+ E + SE D +S +K +G Sbjct: 523 VHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSG 576 >gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor [Homo sapiens] Length = 513 Score = 38.9 bits (89), Expect = 0.015 Identities = 54/257 (21%), Positives = 97/257 (37%), Gaps = 23/257 (8%) Query: 245 EGSDPAHIAERHGHKEL----KKIFEDFSIQEIDINNE-QENDYEEDIASFSTYIPSTQN 299 E S+ A+ + G + L +KIF I E D +E +N+ E++ S ST ++++ Sbjct: 244 ENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRD 303 Query: 300 PAFHHESRKTYGQSADGAEANEMEGE-----GKQNGSGMETKHSPLEVGSESSE------ 348 R + G S + ++ N + E G + S E S E SES E Sbjct: 304 TGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSES 363 Query: 349 --DQYDDLYVFIPGADPENNSQEPLMS--SRPPLPPPRPVANAFQLERPHFTLPGTMVEG 404 D D ++ + ++S+E S A++ E +F+ Sbjct: 364 RGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPE 423 Query: 405 QMERSQNWG---HPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILAN 461 S G H + +E E++ + + +ED + SE D L N Sbjct: 424 DENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKN 483 Query: 462 LSIKKKTGSRSFIINRP 478 + I+ + + N+P Sbjct: 484 IEIESRKLTVDAYHNKP 500 >gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 precursor [Homo sapiens] Length = 497 Score = 38.9 bits (89), Expect = 0.015 Identities = 54/257 (21%), Positives = 97/257 (37%), Gaps = 23/257 (8%) Query: 245 EGSDPAHIAERHGHKEL----KKIFEDFSIQEIDINNE-QENDYEEDIASFSTYIPSTQN 299 E S+ A+ + G + L +KIF I E D +E +N+ E++ S ST ++++ Sbjct: 228 ENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRD 287 Query: 300 PAFHHESRKTYGQSADGAEANEMEGE-----GKQNGSGMETKHSPLEVGSESSE------ 348 R + G S + ++ N + E G + S E S E SES E Sbjct: 288 TGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSES 347 Query: 349 --DQYDDLYVFIPGADPENNSQEPLMS--SRPPLPPPRPVANAFQLERPHFTLPGTMVEG 404 D D ++ + ++S+E S A++ E +F+ Sbjct: 348 RGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPE 407 Query: 405 QMERSQNWG---HPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILAN 461 S G H + +E E++ + + +ED + SE D L N Sbjct: 408 DENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKN 467 Query: 462 LSIKKKTGSRSFIINRP 478 + I+ + + N+P Sbjct: 468 IEIESRKLTVDAYHNKP 484 >gi|14277690 hypothetical protein LOC9750 isoform 2 [Homo sapiens] Length = 591 Score = 38.9 bits (89), Expect = 0.015 Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 12/112 (10%) Query: 238 ASKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEE------DIASFS 291 ASKMK + PA A R E+ + F++++ I E EN E +A F+ Sbjct: 156 ASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFA 215 Query: 292 TYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVG 343 P Q F R+ + ++E GKQ+ G ET PL VG Sbjct: 216 RLCPGDQYEIFMKYGRQRWKLK------GKIEVNGKQSWDGEETVFLPLIVG 261 >gi|164414421 hypothetical protein LOC9750 isoform 1 [Homo sapiens] Length = 1068 Score = 38.9 bits (89), Expect = 0.015 Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 12/112 (10%) Query: 238 ASKMKNMEGSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEE------DIASFS 291 ASKMK + PA A R E+ + F++++ I E EN E +A F+ Sbjct: 156 ASKMKQAFATSPASKAARESLTEINRSFKEYTENMCTIEVELENLLGEFSIKMKGLAGFA 215 Query: 292 TYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGMETKHSPLEVG 343 P Q F R+ + ++E GKQ+ G ET PL VG Sbjct: 216 RLCPGDQYEIFMKYGRQRWKLK------GKIEVNGKQSWDGEETVFLPLIVG 261 >gi|55741655 anoctamin 8 [Homo sapiens] Length = 1232 Score = 38.5 bits (88), Expect = 0.020 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 8/113 (7%) Query: 420 ETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPP 479 E GD P G KE+ E+++E+E+EE+ E + E ++ L +KK + + R P Sbjct: 572 EEGDGPPGGKEEDEDDEEEEDEEEEED--EEEGEEGGLLDCGLRLKKVSFAERGAGRRRP 629 Query: 480 APTPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFCGLPKKQDRARIESPA 532 P+P +E + + + + +DD+ G P +R E PA Sbjct: 630 GPSPEALL---EEGSPTMVEKGLEPGVFTLAEEDDEAEGAPGSPER---EPPA 676 >gi|117553584 adaptor-related protein complex 3, delta 1 subunit isoform 1 [Homo sapiens] Length = 1112 Score = 38.5 bits (88), Expect = 0.020 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 16/102 (15%) Query: 424 EPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINR--PPAP 481 E K +K KK+E+K +E+E D E + KK F ++ PPAP Sbjct: 747 EKKSKKPKKKEKKHKEKERDKEKKKEKE--------------KKAEDLDFWLSTTPPPAP 792 Query: 482 TPRPTSIPPKEETTPYIAQVFQQKTARRQSDDDKFCGLPKKQ 523 P P +P +E + ++ D DK PKK+ Sbjct: 793 APAPAPVPSTDECEDAKTEAQGEEDDAEGQDQDKKSPKPKKK 834 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 38.5 bits (88), Expect = 0.020 Identities = 44/202 (21%), Positives = 77/202 (38%), Gaps = 14/202 (6%) Query: 246 GSDPAHIAERHGHKELKKIFEDFSIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHE 305 G +AE+ K K+ E+ +E + +++E + E + + + E Sbjct: 690 GEGEKELAEKEEWK--KRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREE 747 Query: 306 SRKTYGQSADGAEANEMEGEG-KQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPE 364 + G+ + E E+EGE K+ G + + + E E DQ + G + E Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGE-------GEEEE 800 Query: 365 NNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHP----GVRQE 420 + + + E G EG+ E + G G +E Sbjct: 801 TEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE 860 Query: 421 TGDEPKGEKEKKEEEKEQEEEE 442 G+E +GE+E +E E E EEEE Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEE 882 Score = 34.7 bits (78), Expect = 0.28 Identities = 34/136 (25%), Positives = 50/136 (36%), Gaps = 42/136 (30%) Query: 312 QSADGAEANEMEGEGKQNGSGMETK-HSPLEVGSESSEDQYDDLYVFIPGADPENNSQEP 370 + D E E EGEGK+ G G E + E G E++ A E +E Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER----------AGKEEKGEEE 790 Query: 371 LMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHP---GVRQETGDEPKG 427 G EG+ E ++ G G E G+ +G Sbjct: 791 ----------------------------GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822 Query: 428 EKEKKEEEKEQEEEED 443 + E++EEE+E E EE+ Sbjct: 823 KGEREEEEEEGEGEEE 838 Score = 32.3 bits (72), Expect = 1.4 Identities = 16/45 (35%), Positives = 28/45 (62%), Gaps = 4/45 (8%) Query: 403 EGQMERSQNWGHPGVR----QETGDEPKGEKEKKEEEKEQEEEED 443 E Q ++ + GH R +E G+E GE E++E ++E+EEE++ Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752 Score = 32.3 bits (72), Expect = 1.4 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 7/53 (13%) Query: 402 VEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSE 454 VEG++E + G G+E +GE+E +E EKE E EE+ E ++ E Sbjct: 1021 VEGEVEGEEGEGE-------GEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066 Score = 32.0 bits (71), Expect = 1.8 Identities = 14/52 (26%), Positives = 29/52 (55%) Query: 403 EGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSE 454 EG+ ++ + G +E GD+ +GE+E+ E E++EE E+++ + Sbjct: 772 EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823 Score = 32.0 bits (71), Expect = 1.8 Identities = 32/134 (23%), Positives = 49/134 (36%), Gaps = 36/134 (26%) Query: 311 GQSADG-AEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQE 369 G+ +G E E EGEG++ G G + G E E + ++ + E +E Sbjct: 871 GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEE-------EEGEGKGEE 923 Query: 370 PLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEK 429 G EG+ E + G + G+E +GE Sbjct: 924 E----------------------------GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955 Query: 430 EKKEEEKEQEEEED 443 E +EEE E E EE+ Sbjct: 956 EGEEEEGEGEGEEE 969 Score = 30.8 bits (68), Expect = 4.1 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 7/59 (11%) Query: 403 EGQMERSQNWGHPGVRQETGDEPKGEKEKKEE-------EKEQEEEEDPYTFAEIDDSE 454 EG+ E + G + G+E +GE+E +EE E E EEEE+ E++ E Sbjct: 971 EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029 Score = 30.8 bits (68), Expect = 4.1 Identities = 29/127 (22%), Positives = 48/127 (37%), Gaps = 29/127 (22%) Query: 311 GQSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEP 370 G+ +G E E EGEG++ G G E E++ ++ + G + E +E Sbjct: 990 GEEEEGEEEGEEEGEGEEEGEG------------EGEEEEEGEVEGEVEGEEGEGEGEE- 1036 Query: 371 LMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKE 430 + E G E + R + G QETG+E + E++ Sbjct: 1037 ---------------EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEE-ENERQ 1080 Query: 431 KKEEEKE 437 EE K+ Sbjct: 1081 DGEEYKK 1087 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 38.5 bits (88), Expect = 0.020 Identities = 54/192 (28%), Positives = 74/192 (38%), Gaps = 19/192 (9%) Query: 312 QSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPEN---NSQ 368 Q A+G EA E EGE + G+E + E ES + D A PE+ +Q Sbjct: 2111 QKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAE---GEAQPESEGIEAQ 2167 Query: 369 EPLMSSRPPL---PPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEP 425 E ++P L P A Q E P E Q E + P +E EP Sbjct: 2168 EAEEEAQPELEGVEAPEAEGEA-QPESEGIEAPEAEGEAQPE-LEGVEAPEAEEEAQPEP 2225 Query: 426 KGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRP 485 +G E E E E + E + T E S + L + ++ + S S P P RP Sbjct: 2226 EG-VETPEAEGEAQPESEGETQGEKKGSP-QVSLGDGQSEEASESSS------PVPEDRP 2277 Query: 486 TSIPPKEETTPY 497 T P TP+ Sbjct: 2278 TPPPSPGGDTPH 2289 Score = 33.1 bits (74), Expect = 0.83 Identities = 35/143 (24%), Positives = 57/143 (39%), Gaps = 11/143 (7%) Query: 311 GQS--ADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGAD----PE 364 GQS A+G EA E EGE + G+E + + E Q + V P A+ PE Sbjct: 1827 GQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPE 1886 Query: 365 NNSQEPLMSSRPPLPPPRPVANAFQLER----PHFTLPGTMVEGQMERSQNWGHPGVRQE 420 + E + + P A A + E+ ++ EG+ E +E Sbjct: 1887 SEDVE-TPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945 Query: 421 TGDEPKGEKEKKEEEKEQEEEED 443 E +G+ + + E E +E E+ Sbjct: 1946 AAQEAEGQTQPESEVIESQEAEE 1968 Score = 31.2 bits (69), Expect = 3.1 Identities = 28/132 (21%), Positives = 48/132 (36%), Gaps = 2/132 (1%) Query: 318 EANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPP 377 E E EGE + +E + E+ E Q + V +QE ++ Sbjct: 1985 ETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKT 2044 Query: 378 LPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKE 437 +P ++ +E P EG+++ ++ HP E +GE + + E E Sbjct: 2045 EGDAQPESDG--VEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVE 2102 Query: 438 QEEEEDPYTFAE 449 E E AE Sbjct: 2103 APEAEGEAQKAE 2114 Score = 29.6 bits (65), Expect = 9.1 Identities = 26/130 (20%), Positives = 51/130 (39%), Gaps = 11/130 (8%) Query: 314 ADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMS 373 ++GAEA E E E + +E + E ES + + A+ + + ++ Sbjct: 1903 SEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIE 1962 Query: 374 SRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKE 433 S+ +P + + +E ++E + G E + P+ E E +E Sbjct: 1963 SQEAEEEAQPESEDVEA-----------LEVEVETQEAEGEAQPESEDVEAPEAEGEMQE 2011 Query: 434 EEKEQEEEED 443 E+E + E D Sbjct: 2012 AEEEAQPESD 2021 >gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens] Length = 1651 Score = 38.1 bits (87), Expect = 0.026 Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 13/156 (8%) Query: 212 TLLHCAAKFGLKNLAIHLLQCSGATWASKMKNMEGSDPAHIAERHGHKELKKIFEDF--- 268 +LLH A ++GL L+ L G A + N EG+ P +A R GH +L + +F Sbjct: 165 SLLHLAMRWGLAKLSQFFLCLPGGVQALALPNEEGATPLDLALREGHSKLVEDVTNFQGR 224 Query: 269 ---SIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHE---SRKTYGQSADGAEANEM 322 S + ++ E Y + + + T + RK + A +A E Sbjct: 225 WSPSFSRVQLSEEASLHYIHSSETLTLTLNHTAEHLLEADIKLFRKYFWDRAFLVKAFEP 284 Query: 323 EGEGKQN----GSGMETKHSPLEVGSESSEDQYDDL 354 E ++ SG ET+ S S + +D+ Sbjct: 285 EARPEERTAMPSSGAETEEEIKNSVSSRSAAEKEDI 320 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 38.1 bits (87), Expect = 0.026 Identities = 42/183 (22%), Positives = 73/183 (39%), Gaps = 34/183 (18%) Query: 275 INNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGME 334 +N+E ++D EE ++ P + H + +DG E + + K++ E Sbjct: 1282 VNSESDSDSEE-----------SKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEH---KE 1327 Query: 335 TK-HSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERP 393 K + +V SE SED E+ E + S P A +LE Sbjct: 1328 VKGRNRRKVSSEDSEDSDFQ----------ESGVSEEVSESEDEQRPRTRSAKKAELEEN 1377 Query: 394 HFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDS 453 + ++ + V++++ E K E++EEEKE+EEEE+ E +D Sbjct: 1378 ---------QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1428 Query: 454 EYD 456 D Sbjct: 1429 NDD 1431 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 38.1 bits (87), Expect = 0.026 Identities = 42/183 (22%), Positives = 73/183 (39%), Gaps = 34/183 (18%) Query: 275 INNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGKQNGSGME 334 +N+E ++D EE ++ P + H + +DG E + + K++ E Sbjct: 1320 VNSESDSDSEE-----------SKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEH---KE 1365 Query: 335 TK-HSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERP 393 K + +V SE SED E+ E + S P A +LE Sbjct: 1366 VKGRNRRKVSSEDSEDSDFQ----------ESGVSEEVSESEDEQRPRTRSAKKAELEEN 1415 Query: 394 HFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDS 453 + ++ + V++++ E K E++EEEKE+EEEE+ E +D Sbjct: 1416 ---------QRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1466 Query: 454 EYD 456 D Sbjct: 1467 NDD 1469 >gi|209862789 microtubule associated monoxygenase, calponin and LIM domain containing 3 isoform 1 [Homo sapiens] Length = 2002 Score = 37.4 bits (85), Expect = 0.044 Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 29/145 (20%) Query: 312 QSADGAEANEMEGEGKQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPL 371 + A+ + E + + N S + + +V S SSE + ++ + E +EP Sbjct: 901 RQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESEMEE--------EGEEEEEEPR 952 Query: 372 MSSRPPLPPPRPVANAFQLE--RPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEK 429 + PP + E R H L G E ++E S+++G P E+ Sbjct: 953 L-------PPSDLGGVPWKEAVRIHALLKGKSEE-ELEASKSFG-----------PGNEE 993 Query: 430 EKKEEEKEQEEEEDPYTFAEIDDSE 454 E++EEE+ +EEEE+ Y E + SE Sbjct: 994 EEEEEEEYEEEEEEDYDEEEEESSE 1018 >gi|50726968 microfibrillar-associated protein 1 [Homo sapiens] Length = 439 Score = 37.4 bits (85), Expect = 0.044 Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 26/133 (19%) Query: 327 KQNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGA---DPENNSQEPLMSSRPPLPPPRP 383 K+ SG ++P+E S D+ D+ + FI A + E QE SS P L R Sbjct: 37 KRYVSGKRPDYAPME-----SSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRL---RR 88 Query: 384 VANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEED 443 + N + VE ++ R + P V E+ E +G+ + E E EEEE+ Sbjct: 89 LQNRISED----------VEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEE 138 Query: 444 PYTFAEIDDSEYD 456 EIDD E + Sbjct: 139 -----EIDDEEIE 146 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 37.0 bits (84), Expect = 0.057 Identities = 20/71 (28%), Positives = 40/71 (56%), Gaps = 4/71 (5%) Query: 419 QETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSF----I 474 +E +E + E+E++EEE+E+EEEE+ E ++ E + ++ ++ T S Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327 Query: 475 INRPPAPTPRP 485 + P +P+P+P Sbjct: 328 LRGPESPSPKP 338 Score = 31.6 bits (70), Expect = 2.4 Identities = 16/48 (33%), Positives = 29/48 (60%) Query: 407 ERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSE 454 E S+ G +E +E + E+E++E+E+E+EEEE+ E ++ E Sbjct: 247 ESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294 >gi|118600967 shroom family member 4 [Homo sapiens] Length = 1493 Score = 36.6 bits (83), Expect = 0.075 Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 12/84 (14%) Query: 365 NNSQEPLMSSR----PPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGVRQE 420 + +Q L+ +R PP PP P ++L R + Q ++ Q +E Sbjct: 1085 DETQSDLLGARKKAFPPPRPPPPNWEKYRLFRA--------AQQQKQQQQQQKQQEEEEE 1136 Query: 421 TGDEPKGEKEKKEEEKEQEEEEDP 444 +E + E+E++EEE E+EEEE P Sbjct: 1137 EEEEEEEEEEEEEEEAEEEEEELP 1160 Score = 32.3 bits (72), Expect = 1.4 Identities = 14/37 (37%), Positives = 26/37 (70%) Query: 418 RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSE 454 +Q+ + + E+E++EEE+E+EEEE+ AE ++ E Sbjct: 1122 KQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158 Score = 30.0 bits (66), Expect = 7.0 Identities = 12/40 (30%), Positives = 27/40 (67%) Query: 418 RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDM 457 +Q+ + + ++E++EEE+E+EEEE+ E ++ E ++ Sbjct: 1120 QQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEEL 1159 >gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 36.6 bits (83), Expect = 0.075 Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 17/121 (14%) Query: 390 LERPHFTLPGTMVEGQMERSQNWGHPGVRQETGDEPKGEKEKKEEEKEQEEE-------- 441 LE P P T E Q ER + ++ E E+EK+ +E+E++E Sbjct: 499 LEAPEPRKPVTAQERQREREE-------KRRRRQERAKEREKRRQERERKERGAGASGGP 551 Query: 442 -EDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRP-PAPTPRPTSIPPKEETTPYIA 499 DP + D++ ++ + + + P PAPTP PT + P +A Sbjct: 552 STDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVA 611 Query: 500 Q 500 Q Sbjct: 612 Q 612 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.132 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,278,028 Number of Sequences: 37866 Number of extensions: 1648453 Number of successful extensions: 17147 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 179 Number of HSP's successfully gapped in prelim test: 272 Number of HSP's that attempted gapping in prelim test: 12659 Number of HSP's gapped (non-prelim): 2799 length of query: 652 length of database: 18,247,518 effective HSP length: 109 effective length of query: 543 effective length of database: 14,120,124 effective search space: 7667227332 effective search space used: 7667227332 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.