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Search of human proteins with 187761317
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187761317 tet oncogene family member 2 isoform a [Homo
sapiens]
(2002 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens] 4103 0.0
gi|116063558 tet oncogene family member 2 isoform b [Homo sapiens] 2325 0.0
gi|149944516 tet oncogene family member 3 [Homo sapiens] 606 e-173
gi|156139122 CXXC finger 6 [Homo sapiens] 523 e-148
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 60 3e-08
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 60 3e-08
gi|221139761 zinc finger protein 853 [Homo sapiens] 55 5e-07
gi|33286444 mastermind-like 2 [Homo sapiens] 55 5e-07
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho... 55 9e-07
gi|93141033 PAX interacting protein 1 [Homo sapiens] 53 3e-06
gi|226246533 TOX high mobility group box family member 3 isoform... 51 1e-05
gi|226054295 TOX high mobility group box family member 3 isoform... 51 1e-05
gi|5174545 myocyte enhancer factor 2D [Homo sapiens] 51 1e-05
gi|38158015 mastermind-like 3 [Homo sapiens] 50 2e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 49 5e-05
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 48 1e-04
gi|148922920 DENN/MADD domain containing 4B [Homo sapiens] 47 2e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 46 3e-04
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 45 5e-04
gi|44890059 involucrin [Homo sapiens] 45 7e-04
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 44 0.001
gi|110347429 mediator complex subunit 12 [Homo sapiens] 44 0.001
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 44 0.001
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 44 0.002
gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] 44 0.002
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 44 0.002
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 43 0.003
gi|116805330 small conductance calcium-activated potassium chann... 43 0.004
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 43 0.004
gi|116235460 YTH domain family, member 3 [Homo sapiens] 43 0.004
>gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens]
Length = 2002
Score = 4103 bits (10642), Expect = 0.0
Identities = 2002/2002 (100%), Positives = 2002/2002 (100%)
Query: 1 MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY 60
MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY
Sbjct: 1 MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY 60
Query: 61 YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG 120
YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG
Sbjct: 61 YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG 120
Query: 121 ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ 180
ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ
Sbjct: 121 ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ 180
Query: 181 ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI 240
ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI
Sbjct: 181 ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI 240
Query: 241 AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD 300
AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD
Sbjct: 241 AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD 300
Query: 301 ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL 360
ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL
Sbjct: 301 ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL 360
Query: 361 QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS 420
QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS
Sbjct: 361 QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS 420
Query: 421 EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP
Sbjct: 421 EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
Query: 481 QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI 540
QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI
Sbjct: 481 QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI 540
Query: 541 LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM 600
LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM
Sbjct: 541 LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM 600
Query: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV 660
TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV
Sbjct: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV 660
Query: 661 HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ 720
HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ
Sbjct: 661 HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ 720
Query: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK
Sbjct: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
Query: 781 VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL 840
VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL
Sbjct: 781 VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL 840
Query: 841 VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK 900
VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK
Sbjct: 841 VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK 900
Query: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ 960
NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ
Sbjct: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ 960
Query: 961 EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ 1020
EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ
Sbjct: 961 EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ 1020
Query: 1021 QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA 1080
QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA
Sbjct: 1021 QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA 1080
Query: 1081 LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVEQII 1140
LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVEQII
Sbjct: 1081 LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCVEQII 1140
Query: 1141 EKDEGPFYTHLGAGPNVAAIREIMEERFGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVV 1200
EKDEGPFYTHLGAGPNVAAIREIMEERFGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVV
Sbjct: 1141 EKDEGPFYTHLGAGPNVAAIREIMEERFGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVV 1200
Query: 1201 RRSSSEEKLLCLVRERAGHTCEAAVIVILILVWEGIPLSLADKLYSELTETLRKYGTLTN 1260
RRSSSEEKLLCLVRERAGHTCEAAVIVILILVWEGIPLSLADKLYSELTETLRKYGTLTN
Sbjct: 1201 RRSSSEEKLLCLVRERAGHTCEAAVIVILILVWEGIPLSLADKLYSELTETLRKYGTLTN 1260
Query: 1261 RRCALNEERTCACQGLDPETCGASFSFGCSWSMYYNGCKFARSKIPRKFKLLGDDPKEEE 1320
RRCALNEERTCACQGLDPETCGASFSFGCSWSMYYNGCKFARSKIPRKFKLLGDDPKEEE
Sbjct: 1261 RRCALNEERTCACQGLDPETCGASFSFGCSWSMYYNGCKFARSKIPRKFKLLGDDPKEEE 1320
Query: 1321 KLESHLQNLSTLMAPTYKKLAPDAYNNQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAH 1380
KLESHLQNLSTLMAPTYKKLAPDAYNNQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAH
Sbjct: 1321 KLESHLQNLSTLMAPTYKKLAPDAYNNQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAH 1380
Query: 1381 AHRDLHNMQNGSTLVCTLTREDNREFGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKR 1440
AHRDLHNMQNGSTLVCTLTREDNREFGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKR
Sbjct: 1381 AHRDLHNMQNGSTLVCTLTREDNREFGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKR 1440
Query: 1441 SGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTK 1500
SGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTK
Sbjct: 1441 SGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTK 1500
Query: 1501 QTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSY 1560
QTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSY
Sbjct: 1501 QTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSY 1560
Query: 1561 SASGSTNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPG 1620
SASGSTNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPG
Sbjct: 1561 SASGSTNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPG 1620
Query: 1621 LLNQNTQYPSYQCNGNLSVDNCSPYLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQ 1680
LLNQNTQYPSYQCNGNLSVDNCSPYLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQ
Sbjct: 1621 LLNQNTQYPSYQCNGNLSVDNCSPYLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQ 1680
Query: 1681 PRFGNSQSFTSKYLGYGNQNMQGDGFSSCTIRPNVHHVGKLPPYPTHEMDGHFMGATSRL 1740
PRFGNSQSFTSKYLGYGNQNMQGDGFSSCTIRPNVHHVGKLPPYPTHEMDGHFMGATSRL
Sbjct: 1681 PRFGNSQSFTSKYLGYGNQNMQGDGFSSCTIRPNVHHVGKLPPYPTHEMDGHFMGATSRL 1740
Query: 1741 PPNLSNPNMDYKNGEHHSPSHIIHNYSAAPGMFNSSLHALHLQNKENDMLSHTANGLSKM 1800
PPNLSNPNMDYKNGEHHSPSHIIHNYSAAPGMFNSSLHALHLQNKENDMLSHTANGLSKM
Sbjct: 1741 PPNLSNPNMDYKNGEHHSPSHIIHNYSAAPGMFNSSLHALHLQNKENDMLSHTANGLSKM 1800
Query: 1801 LPALNHDRTACVQGGLHKLSDANGQEKQPLALVQGVASGAEDNDEVWSDSEQSFLDPDIG 1860
LPALNHDRTACVQGGLHKLSDANGQEKQPLALVQGVASGAEDNDEVWSDSEQSFLDPDIG
Sbjct: 1801 LPALNHDRTACVQGGLHKLSDANGQEKQPLALVQGVASGAEDNDEVWSDSEQSFLDPDIG 1860
Query: 1861 GVAVAPTHGSILIECAKRELHATTPLKNPNRNHPTRISLVFYQHKSMNEPKHGLALWEAK 1920
GVAVAPTHGSILIECAKRELHATTPLKNPNRNHPTRISLVFYQHKSMNEPKHGLALWEAK
Sbjct: 1861 GVAVAPTHGSILIECAKRELHATTPLKNPNRNHPTRISLVFYQHKSMNEPKHGLALWEAK 1920
Query: 1921 MAEKAREKEEECEKYGPDYVPQKSHGKKVKREPAEPHETSEPTYLRFIKSLAERTMSVTT 1980
MAEKAREKEEECEKYGPDYVPQKSHGKKVKREPAEPHETSEPTYLRFIKSLAERTMSVTT
Sbjct: 1921 MAEKAREKEEECEKYGPDYVPQKSHGKKVKREPAEPHETSEPTYLRFIKSLAERTMSVTT 1980
Query: 1981 DSTVTTSPYAFTRVTGPYNRYI 2002
DSTVTTSPYAFTRVTGPYNRYI
Sbjct: 1981 DSTVTTSPYAFTRVTGPYNRYI 2002
>gi|116063558 tet oncogene family member 2 isoform b [Homo sapiens]
Length = 1165
Score = 2325 bits (6025), Expect = 0.0
Identities = 1136/1136 (100%), Positives = 1136/1136 (100%)
Query: 1 MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY 60
MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY
Sbjct: 1 MEQDRTNHVEGNRLSPFLIPSPPICQTEPLATKLQNGSPLPERAHPEVNGDTKWHSFKSY 60
Query: 61 YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG 120
YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG
Sbjct: 61 YGIPCMKGSQNSRVSPDFTQESRGYSKCLQNGGIKRTVSEPSLSGLLQIKKLKQDQKANG 120
Query: 121 ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ 180
ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ
Sbjct: 121 ERRNFGVSQERNPGESSQPNVSDLSDKKESVSSVAQENAVKDFTSFSTHNCSGPENPELQ 180
Query: 181 ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI 240
ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI
Sbjct: 181 ILNEQEGKSANYHDKNIVLLKNKAVLMPNGATVSASSVEHTHGELLEKTLSQYYPDCVSI 240
Query: 241 AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD 300
AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD
Sbjct: 241 AVQKTTSHINAINSQATNELSCEITHPSHTSGQINSAQTSNSELPPKPAAVVSEACDADD 300
Query: 301 ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL 360
ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL
Sbjct: 301 ADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNL 360
Query: 361 QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS 420
QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS
Sbjct: 361 QAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSPPPPLPQVPQLPS 420
Query: 421 EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP
Sbjct: 421 EGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
Query: 481 QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI 540
QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI
Sbjct: 481 QNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEI 540
Query: 541 LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM 600
LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM
Sbjct: 541 LKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQM 600
Query: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV 660
TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV
Sbjct: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV 660
Query: 661 HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ 720
HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ
Sbjct: 661 HFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQ 720
Query: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK
Sbjct: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
Query: 781 VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL 840
VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL
Sbjct: 781 VEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHL 840
Query: 841 VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK 900
VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK
Sbjct: 841 VSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYK 900
Query: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ 960
NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ
Sbjct: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQ 960
Query: 961 EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ 1020
EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ
Sbjct: 961 EQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQ 1020
Query: 1021 QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA 1080
QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA
Sbjct: 1021 QKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPA 1080
Query: 1081 LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCV 1136
LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCV
Sbjct: 1081 LEQQTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNLLDTPVKTQYDFPSCRCV 1136
Score = 31.6 bits (70), Expect = 8.2
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 27/129 (20%)
Query: 1460 PVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSG 1519
P + R + ++ +++ S L+ N+N+ + A+Q Q L+
Sbjct: 874 PKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSG--------QQAAQLAQQRYLIHNHA 925
Query: 1520 PVMQQSQQPQPLQKQPPQPQQQ----------QRPQQQQPHHPQTESVNSYSASGSTNPY 1569
V Q + PPQ Q Q+ +QQQ PQTES +S
Sbjct: 926 NVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHS---------Q 976
Query: 1570 MRRPNPVSP 1578
M RP V P
Sbjct: 977 MHRPIKVEP 985
>gi|149944516 tet oncogene family member 3 [Homo sapiens]
Length = 1660
Score = 606 bits (1562), Expect = e-173
Identities = 332/585 (56%), Positives = 401/585 (68%), Gaps = 55/585 (9%)
Query: 1049 KSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQQTTSSEKTPTK--RTAASVLNNFIE 1106
+S KQ+K+E SG VTVL+ T + E TPTK L+ F+E
Sbjct: 617 RSPKQIKIESSGAVTVLS-----------TTCFHSEEGGQEATPTKAENPLTPTLSGFLE 665
Query: 1107 SPSKLLDTPIKNLLDTPVK-TQYDFPSCRCVEQIIEKDEGPFYTHLGAGPNVAAIREIME 1165
SP K LDTP K+LLDTP K Q +FP+C CVEQI+EKDEGP+YTHLG+GP VA+IRE+ME
Sbjct: 666 SPLKYLDTPTKSLLDTPAKRAQAEFPTCDCVEQIVEKDEGPYYTHLGSGPTVASIRELME 725
Query: 1166 ERFGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVVRRSSSEEKLLCLVRERAGHTCEAAV 1225
ER+G+KGKAIRIE+VIYTGKEGKSS+GCPIAKWV+RR + EEKLLCLVR RAGH C+ AV
Sbjct: 726 ERYGEKGKAIRIEKVIYTGKEGKSSRGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAV 785
Query: 1226 IVILILVWEGIPLSLADKLYSELTETLRKYGTLTNRRCALNEERTCACQGLDPETCGASF 1285
IVILIL WEGIP SL D LY ELT+TLRKYG T+RRC LN++RTCACQG DP TCGASF
Sbjct: 786 IVILILAWEGIPRSLGDTLYQELTDTLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASF 845
Query: 1286 SFGCSWSMYYNGCKFARSKIPRKFKLLGDDPKEEEKLESHLQNLSTLMAPTYKKLAPDAY 1345
SFGCSWSMY+NGCK+ARSK PRKF+L GD+PKEEE L Q+L+T +AP YK+LAP AY
Sbjct: 846 SFGCSWSMYFNGCKYARSKTPRKFRLAGDNPKEEEVLRKSFQDLATEVAPLYKRLAPQAY 905
Query: 1346 NNQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAHAHRDLHNMQNGSTLVCTLTREDNRE 1405
NQ+ E A +CRLGLKEGRPF+GVTAC+DFCAHAH+D HN+ NG T+VCTLT+EDNR
Sbjct: 906 QNQVTNEEIAIDCRLGLKEGRPFAGVTACMDFCAHAHKDQHNLYNGCTVVCTLTKEDNRC 965
Query: 1406 FGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCR 1465
G PEDEQLHVLPLYK+++ DEFGS E Q K SGAIQVL++F R+VR L EP K+CR
Sbjct: 966 VGKIPEDEQLHVLPLYKMANTDEFGSEENQNAKVGSGAIQVLTAFPREVRRLPEPAKSCR 1025
Query: 1466 QRKLEAKKAAAEKLSSLENSSNKNEKEK-SAPSRTKQTENASQAKQLAEL-----LRLSG 1519
QR+LEA+KAAAEK K +KEK S P + KQ +A +LA + L L G
Sbjct: 1026 QRQLEARKAAAEK--------KKIQKEKLSTPEKIKQ-----EALELAGITSDPGLSLKG 1072
Query: 1520 PVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPY 1579
+ QQ +P L+ +P + + V SYS G+ P PY
Sbjct: 1073 GLSQQGLKPS-LKVEPQNHFSSFK-------YSGNAVVESYSVLGNC-------RPSDPY 1117
Query: 1580 P-NSSHTSDIY----GSTSPMNFYSTSSQAAGSYLN--SSNPMNP 1617
NS ++ Y TS F+S + + SY SSNP+ P
Sbjct: 1118 SMNSVYSYHSYYAQPSLTSVNGFHSKYALPSFSYYGFPSSNPVFP 1162
Score = 189 bits (481), Expect = 2e-47
Identities = 100/175 (57%), Positives = 124/175 (70%), Gaps = 11/175 (6%)
Query: 1834 QGVASGAEDNDEVWSDSEQSFLDPDIGGVAVAPTHGSILIECAKRELHATTPLKNPNRNH 1893
+G E+ +E+WSDSE +FLD +IGGVAVAP HGSILIECA+RELHATTPLK PNR H
Sbjct: 1491 KGGGGAEEEEEELWSDSEHNFLDENIGGVAVAPAHGSILIECARRELHATTPLKKPNRCH 1550
Query: 1894 PTRISLVFYQHKSMNEPKHGLALWEAKM---AEKAREKEEECEKYGPDYVPQKSHGKKVK 1950
PTRISLVFYQHK++N+P HGLALWEAKM AE+AR ++EE + G K +GKK K
Sbjct: 1551 PTRISLVFYQHKNLNQPNHGLALWEAKMKQLAERARARQEEAARLGLGQQEAKLYGKKRK 1610
Query: 1951 ---REPAEPHETSEPTYLRFIKSLAERTMSVTTDSTVTTSPYAFTRVTGPYNRYI 2002
AEP + + + ++LA V TDS VT S YA+T+VTGPY+R+I
Sbjct: 1611 WGGTVVAEPQQKEKKGVVPTRQALA-----VPTDSAVTVSSYAYTKVTGPYSRWI 1660
Score = 32.3 bits (72), Expect = 4.8
Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 26/133 (19%)
Query: 170 NCSGPENPELQILNEQEGKSANYHDKNIVLLKNK------AVLMPNGATVSASSVEHTHG 223
NC GPE P+ L EGK K++V+ + L P A + A S
Sbjct: 138 NCDGPECPDY--LEWLEGKI-----KSVVMEGGEERPRLPGPLPPGEAGLPAPSTR---- 186
Query: 224 ELLEKTLSQYYPD--------CVSIAVQKTTSHINAINSQATNELSCEITHPSHTSGQIN 275
LL + Q P +SIA +K S AI +A +LS + PSH++ Q
Sbjct: 187 PLLSSEVPQISPQEGLPLSQSALSIAKEKNISLQTAIAIEALTQLSSALPQPSHSTPQA- 245
Query: 276 SAQTSNSELPPKP 288
S + PP P
Sbjct: 246 SCPLPEALSPPAP 258
>gi|156139122 CXXC finger 6 [Homo sapiens]
Length = 2136
Score = 523 bits (1347), Expect = e-148
Identities = 304/687 (44%), Positives = 401/687 (58%), Gaps = 41/687 (5%)
Query: 1000 NKTWKKVTKQENPPASCDNV---------QQKSIIETMEQHLKQFHA---KSLFDHKALT 1047
N+ +T+ +PP C NV QQ + M Q L ++ ALT
Sbjct: 1293 NQKAHPLTQPSSPPNQCANVMAGDDQIRFQQVVKEQLMHQRLPTLPGISHETPLPESALT 1352
Query: 1048 LKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQQTTSSEKTPTKRTAASVLNNFIES 1107
L++ V V SG +TV++ T + E+ +SS T T S NF +
Sbjct: 1353 LRN---VNVVCSGGITVVS-----------TKSEEEVCSSSFGTSEFSTVDSAQKNFNDY 1398
Query: 1108 PSKLLDTPIKNLLDTPVKTQYDFPSCRCVEQIIEKDEGPFYTHLGAGPNVAAIREIMEER 1167
P KNL+ + + P+C C++++I+KD+GP+YTHLGAGP+VAA+REIME R
Sbjct: 1399 AMNFFTNPTKNLVS--ITKDSELPTCSCLDRVIQKDKGPYYTHLGAGPSVAAVREIMENR 1456
Query: 1168 FGQKGKAIRIERVIYTGKEGKSSQGCPIAKWVVRRSSSEEKLLCLVRERAGHTCEAAVIV 1227
+GQKG AIRIE V+YTGKEGKSS GCPIAKWV+RRSS EEK+LCLVR+R GH C AV+V
Sbjct: 1457 YGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLCLVRQRTGHHCPTAVMV 1516
Query: 1228 ILILVWEGIPLSLADKLYSELTETLRKY-GTLTNRRCALNEERTCACQGLDPETCGASFS 1286
+LI+VW+GIPL +AD+LY+ELTE L+ Y G T+RRC LNE RTC CQG+DPETCGASFS
Sbjct: 1517 VLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRTCTCQGIDPETCGASFS 1576
Query: 1287 FGCSWSMYYNGCKFARSKIPRKFKLLGDDPKEEEKLESHLQNLSTLMAPTYKKLAPDAYN 1346
FGCSWSMY+NGCKF RS PR+F++ P E+ LE +LQ+L+T +AP YK+ AP AY
Sbjct: 1577 FGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLHEKNLEDNLQSLATRLAPIYKQYAPVAYQ 1636
Query: 1347 NQIEYEHRAPECRLGLKEGRPFSGVTACLDFCAHAHRDLHNMQNGSTLVCTLTREDNREF 1406
NQ+EYE+ A ECRLG KEGRPFSGVTACLDFCAH HRD+HNM NGST+VCTLTREDNR
Sbjct: 1637 NQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNNGSTVVCTLTREDNRSL 1696
Query: 1407 GGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPV-KTCR 1465
G P+DEQLHVLPLYK+SD DEFGS E E K +SGAI+VL+ R+K +PV ++ +
Sbjct: 1697 GVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLAPRRKKRTCFTQPVPRSGK 1756
Query: 1466 QRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQS 1525
+R + A K+ ++E K K+ S T S L P ++
Sbjct: 1757 KRAAMMTEVLAHKIRAVEKKPIPRIKRKN-NSTTTNNSKPSSLPTLGSNTETVQPEVKSE 1815
Query: 1526 QQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRP--NPVSPYPNSS 1583
+P + K + HP E+ +S S T P N + S
Sbjct: 1816 TEPHFILKSSDNTKTYS--LMPSAPHPVKEASPGFSWSPKTASATPAPLKNDATASCGFS 1873
Query: 1584 HTSDIYGSTSPMNFYSTSSQAA--GSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSV-D 1640
S T P S ++ AA G ++ + P P L+ P + V +
Sbjct: 1874 ERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLP-TLSAPVMEPLINSEPSTGVTE 1932
Query: 1641 NCSPYLGSYSPQ--SQPMDLYRYPSQD 1665
+P+ ++ P + P DL P ++
Sbjct: 1933 PLTPHQPNHQPSFLTSPQDLASSPMEE 1959
Score = 157 bits (397), Expect = 1e-37
Identities = 80/160 (50%), Positives = 109/160 (68%), Gaps = 15/160 (9%)
Query: 1844 DEVWSDSEQSFLDPDIGGVAVAPTHGSILIECAKRELHATTPLKNPNRNHPTRISLVFYQ 1903
DE WSDSE FLD +IGGVA+AP HGS+LIECA+RELHATTP+++PNRNHPTR+SLVFYQ
Sbjct: 1991 DEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVEHPNRNHPTRLSLVFYQ 2050
Query: 1904 HKSMNEPKHGLALWEAKM-AEKAREKEEECEKYGPDYVPQKSHGKKVKREPAEPHETSEP 1962
HK++N+P+HG L + K A++A+ K+ K+ +K + P ++SE
Sbjct: 2051 HKNLNKPQHGFELNKIKFEAKEAKNKK------------MKASEQKDQAANEGPEQSSEV 2098
Query: 1963 TYLRFIKSLAERTMSVTTDSTVTTSPYAFTRVTGPYNRYI 2002
L I S + +++T D+ VT SPYA T V GPYN ++
Sbjct: 2099 NELNQIPS--HKALTLTHDNVVTVSPYALTHVAGPYNHWV 2136
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 59.7 bits (143), Expect = 3e-08
Identities = 66/251 (26%), Positives = 89/251 (35%), Gaps = 63/251 (25%)
Query: 1526 QQPQPLQKQPP------------QPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRP 1573
Q P P Q+QPP QP QQ+PQ Q P ++ YS S P+ + P
Sbjct: 474 QSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP--PYSQQPSQPPHQQSP 531
Query: 1574 NPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQC 1633
+PYP+ T+ + + P S A S P P P L+Q YP
Sbjct: 532 ---APYPSQQSTTQQHPQSQP----PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYP---- 580
Query: 1634 NGNLSVDNCSPYLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFG----NSQSF 1689
PQSQ Y Q PP L Q FG ++ S
Sbjct: 581 ----------------QPQSQQSQQTAYSQQ------RFPPPQELSQDSFGSQASSAPSM 618
Query: 1690 TSKYLGYGNQNMQGDGFSSCTIRPNVHHVGKLPPYPTHEMDGHFMGATSRLPPNLSNPNM 1749
TS G + N+ S RP+ LP + +D MG L P +S +
Sbjct: 619 TSSKGGQEDMNL------SLQSRPS-----SLPDL-SGSIDDLPMGTEGALSPGVSTSGI 666
Query: 1750 DYKNGEHHSPS 1760
GE +P+
Sbjct: 667 SSSQGEQSNPA 677
Score = 38.1 bits (87), Expect = 0.087
Identities = 54/223 (24%), Positives = 75/223 (33%), Gaps = 20/223 (8%)
Query: 1474 AAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQ-QPQPLQ 1532
AAA ++ S ++ AP + Q LA + S P+ Q + +PQP
Sbjct: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP--LARTPQPSSPMDQMGKMRPQPYG 396
Query: 1533 KQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSSHTSDI--YG 1590
P QQQ P Q H S + P + S S+T I YG
Sbjct: 397 GTNPYSQQQGPPSGPQQGHGYPGQPYG-SQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYG 455
Query: 1591 STSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSVDNCSPYLGSYS 1650
P + Q Y N +P + Q P Y + P
Sbjct: 456 QQGPSGY---GQQGQTPYYNQQSP--------HPQQQQPPYSQQPPSQTPHAQPSY-QQQ 503
Query: 1651 PQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFGNSQSFTSKY 1693
PQSQP L SQ P S+ P H + + QS T ++
Sbjct: 504 PQSQPPQL--QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQH 544
Score = 35.4 bits (80), Expect = 0.56
Identities = 48/212 (22%), Positives = 84/212 (39%), Gaps = 20/212 (9%)
Query: 613 GGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSH-QVHFSKTDHLPKA 671
GGL +YTQ+ + + Q H Q Q+P + Q S+T H +
Sbjct: 443 GGL---SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS 499
Query: 672 HVQSLCGTRFHFQQRADSQTEKLMS--PVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQ 729
+QQ+ SQ +L S P Q +Q + P + Q +Q Q
Sbjct: 500 -----------YQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP--YPSQQSTTQQHPQ 546
Query: 730 TQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGEN 789
+QP S Q+ QQQ+ Q + Q +PQ + Q ++ ++ Q ++
Sbjct: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQD 606
Query: 790 QY-SKSSEFETHNVQMGLEEVQNINRRNSPYS 820
+ S++S + G +E N++ ++ P S
Sbjct: 607 SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSS 638
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 5/100 (5%)
Query: 1523 QQSQQPQPLQKQPPQPQQQ-QRP-QQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPY- 1579
QQS Q Q QPP Q Q Q P QQQQP P +++ +A + S
Sbjct: 537 QQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQR 596
Query: 1580 --PNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNP 1617
P + D +GS + TSS+ +N S P
Sbjct: 597 FPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRP 636
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 59.7 bits (143), Expect = 3e-08
Identities = 66/251 (26%), Positives = 89/251 (35%), Gaps = 63/251 (25%)
Query: 1526 QQPQPLQKQPP------------QPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRP 1573
Q P P Q+QPP QP QQ+PQ Q P ++ YS S P+ + P
Sbjct: 474 QSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP--PYSQQPSQPPHQQSP 531
Query: 1574 NPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQC 1633
+PYP+ T+ + + P S A S P P P L+Q YP
Sbjct: 532 ---APYPSQQSTTQQHPQSQP----PYSQPQAQSPYQQQQPQQPAPSTLSQQAAYP---- 580
Query: 1634 NGNLSVDNCSPYLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFG----NSQSF 1689
PQSQ Y Q PP L Q FG ++ S
Sbjct: 581 ----------------QPQSQQSQQTAYSQQ------RFPPPQELSQDSFGSQASSAPSM 618
Query: 1690 TSKYLGYGNQNMQGDGFSSCTIRPNVHHVGKLPPYPTHEMDGHFMGATSRLPPNLSNPNM 1749
TS G + N+ S RP+ LP + +D MG L P +S +
Sbjct: 619 TSSKGGQEDMNL------SLQSRPS-----SLPDL-SGSIDDLPMGTEGALSPGVSTSGI 666
Query: 1750 DYKNGEHHSPS 1760
GE +P+
Sbjct: 667 SSSQGEQSNPA 677
Score = 38.1 bits (87), Expect = 0.087
Identities = 54/223 (24%), Positives = 75/223 (33%), Gaps = 20/223 (8%)
Query: 1474 AAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQ-QPQPLQ 1532
AAA ++ S ++ AP + Q LA + S P+ Q + +PQP
Sbjct: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQP--LARTPQPSSPMDQMGKMRPQPYG 396
Query: 1533 KQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSSHTSDI--YG 1590
P QQQ P Q H S + P + S S+T I YG
Sbjct: 397 GTNPYSQQQGPPSGPQQGHGYPGQPYG-SQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYG 455
Query: 1591 STSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSVDNCSPYLGSYS 1650
P + Q Y N +P + Q P Y + P
Sbjct: 456 QQGPSGY---GQQGQTPYYNQQSP--------HPQQQQPPYSQQPPSQTPHAQPSY-QQQ 503
Query: 1651 PQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFGNSQSFTSKY 1693
PQSQP L SQ P S+ P H + + QS T ++
Sbjct: 504 PQSQPPQL--QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQH 544
Score = 35.4 bits (80), Expect = 0.56
Identities = 48/212 (22%), Positives = 84/212 (39%), Gaps = 20/212 (9%)
Query: 613 GGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSH-QVHFSKTDHLPKA 671
GGL +YTQ+ + + Q H Q Q+P + Q S+T H +
Sbjct: 443 GGL---SYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS 499
Query: 672 HVQSLCGTRFHFQQRADSQTEKLMS--PVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQ 729
+QQ+ SQ +L S P Q +Q + P + Q +Q Q
Sbjct: 500 -----------YQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAP--YPSQQSTTQQHPQ 546
Query: 730 TQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGEN 789
+QP S Q+ QQQ+ Q + Q +PQ + Q ++ ++ Q ++
Sbjct: 547 SQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQD 606
Query: 790 QY-SKSSEFETHNVQMGLEEVQNINRRNSPYS 820
+ S++S + G +E N++ ++ P S
Sbjct: 607 SFGSQASSAPSMTSSKGGQEDMNLSLQSRPSS 638
Score = 33.9 bits (76), Expect = 1.6
Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 5/100 (5%)
Query: 1523 QQSQQPQPLQKQPPQPQQQ-QRP-QQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPY- 1579
QQS Q Q QPP Q Q Q P QQQQP P +++ +A + S
Sbjct: 537 QQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQR 596
Query: 1580 --PNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNP 1617
P + D +GS + TSS+ +N S P
Sbjct: 597 FPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRP 636
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 55.5 bits (132), Expect = 5e-07
Identities = 90/407 (22%), Positives = 148/407 (36%), Gaps = 48/407 (11%)
Query: 689 SQTEKLMSPVLKQHLNQQASETEPFSNSHLLQH-KPHKQAAQTQPSQSSHLPQNQQQQQK 747
S++++ P + Q+ + + P S + + +P ++ Q Q Q P+ QQQ Q
Sbjct: 49 SESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQ--QLEQQPEPQQQPQH 106
Query: 748 LQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLE 807
Q++ + L+ PQ + QQ S Q K + H E + Q+ +
Sbjct: 107 EQLQQPQPHLELQQQPQQDGQQQL--SQLQQEKHQSVHHQE--LKPELQLMHQQQQLQPQ 162
Query: 808 EVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQY 867
+VQ R Q A + QV E +Q + + + L Q
Sbjct: 163 QVQEQQRLQQQQEQLQTQQAQEQQVLQQQ------EQLQQQVQEQQLLQQQQEQLQQQQL 216
Query: 868 FPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANV 927
+Q + QEQ Q+ QQ +LQ Q + QQ AQL QQ L+
Sbjct: 217 LQQQEQLQQQQFQQQ-QEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQ--LLEQQ--- 270
Query: 928 FPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGC 987
Q Q Q+ Q LQ+Q+QQQ Q Q E Q +P +EP
Sbjct: 271 -----QAQLQQQLLLQQQEQ---------LQQQQQQQLLQQQQEQLQQQQLQPPPLEPEE 316
Query: 988 KPHACMHTAPPENKTWKKVTKQENPPASCDNVQQKSIIETMEQHLKQFHAKSLFDHKALT 1047
+ + P + + +++ +Q + +Q+ + EQ Q +
Sbjct: 317 EEEVELELMPVDLGSEQELEQQRQ-----ELERQQELERQQEQRQLQLKLQEELQQLEQQ 371
Query: 1048 LKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQQTTSSEKTPTK 1094
L+ Q+Q L +Q EL +QQ E TP +
Sbjct: 372 LEQQQQ----------QLEQQEVQLELTPVELGAQQQEVQLELTPVQ 408
Score = 42.4 bits (98), Expect = 0.005
Identities = 73/343 (21%), Positives = 124/343 (36%), Gaps = 25/343 (7%)
Query: 615 LPRQAYTQKTTQLEHKSQMY-QVEMNQGQSQGTVDQHLQFQKPSHQV--HFSKTDHLPKA 671
L +Q Q+ Q E Q +E+ Q Q Q Q Q+ HQ H L
Sbjct: 94 LEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLM 153
Query: 672 HVQS-LCGTRFHFQQRADSQTEKLMSPVLKQH--LNQQASETEPFSNSHLLQHKPHKQAA 728
H Q L + QQR Q E+L + ++ L QQ + LLQ + +
Sbjct: 154 HQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQ 213
Query: 729 QTQPSQSSHLPQNQQQQQKLQIKNKEEIL----------QTFPHPQSNNDQQREGSFFGQ 778
Q Q L Q Q QQQ+ Q++ ++++L Q Q+ QQ Q
Sbjct: 214 QQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQ 273
Query: 779 TKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNT 838
+ + + Q + + + +Q E++Q + P + + ++++
Sbjct: 274 LQQQLLLQQQEQLQQQQQQQL--LQQQQEQLQQ-QQLQPPPLEPEEEEEVELELM---PV 327
Query: 839 HLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQG 898
L SE + + EL + Q L Q + Q+ L + Q+ EQ+ QQ +
Sbjct: 328 DLGSEQELEQQRQEL---ERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEV 384
Query: 899 YKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTP 941
G Q ++ + + + VP GG P
Sbjct: 385 QLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVP 427
Score = 38.5 bits (88), Expect = 0.067
Identities = 30/140 (21%), Positives = 63/140 (45%), Gaps = 9/140 (6%)
Query: 1409 KPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCRQRK 1468
KPE + +H + V E ++ Q+E+ ++ Q +++ ++ Q++
Sbjct: 147 KPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQL---------QQQ 197
Query: 1469 LEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQP 1528
++ ++ ++ L+ ++E+ + +Q + Q +Q LL+ G + QQ Q
Sbjct: 198 VQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQ 257
Query: 1529 QPLQKQPPQPQQQQRPQQQQ 1548
Q Q Q +QQQ QQQ
Sbjct: 258 QQAQLQQQLLEQQQAQLQQQ 277
Score = 35.8 bits (81), Expect = 0.43
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 11/80 (13%)
Query: 1483 ENSSNKNEKEKSAP----SRTKQTENASQAKQLAELLRLSGPVMQ----QSQQPQP---L 1531
E +S+ SAP ++T + QL +L + P Q Q QQPQP L
Sbjct: 59 ERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLEL 118
Query: 1532 QKQPPQPQQQQRPQQQQPHH 1551
Q+QP Q QQQ Q QQ H
Sbjct: 119 QQQPQQDGQQQLSQLQQEKH 138
Score = 31.6 bits (70), Expect = 8.2
Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 1500 KQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTE 1555
+Q QA+ +LL +QQ QQ Q LQ+Q Q QQQQ Q P P+ E
Sbjct: 264 QQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQ--LQPPPLEPEEE 317
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 55.5 bits (132), Expect = 5e-07
Identities = 74/297 (24%), Positives = 109/297 (36%), Gaps = 37/297 (12%)
Query: 714 SNSHLLQHKPHKQAA-QTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE 772
S S + P QA QT S LP Q+ Q+K Q Q + Q +
Sbjct: 399 STSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQP 458
Query: 773 GSF-------------FGQTKVEECFHGENQYS-KSSEFETHNVQMGLEEVQ-NINRRNS 817
++ FGQ K+ G+ +S +SS G +V N +
Sbjct: 459 TNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAG 518
Query: 818 PYSQ------TMKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNN 871
P +Q M+ + S NN H E ++ T P LF N Q M +
Sbjct: 519 PSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKP-LFHFNSDQANQQMP----S 573
Query: 872 VIPKQD---LLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVF 928
V+P Q+ LLH Q+Q+Q+ QQ Q + + Q QQ Q Q
Sbjct: 574 VLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQ---- 629
Query: 929 PVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEP 985
Q S Q+ Q+ + Q+Q+QQQ QQP ++ S +P+ P
Sbjct: 630 ---QQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
Score = 45.8 bits (107), Expect = 4e-04
Identities = 85/384 (22%), Positives = 129/384 (33%), Gaps = 82/384 (21%)
Query: 1483 ENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQ 1542
+ + ++++ + +Q + +S + Q + + S QQ QQ Q Q+Q Q QQQQ
Sbjct: 600 QQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ 659
Query: 1543 RPQQQQPHHPQTESVNSYSASGSTNPYMRRPNP---------------------VSPYPN 1581
+ QQQQP +S+ S P +R P P VS
Sbjct: 660 QQQQQQPSSQPAQSLPS-------QPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQR 712
Query: 1582 SSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSVDN 1641
S + +T P S S + S MN LLNQ +
Sbjct: 713 QDQHSVVGQNTGP----SPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQK 768
Query: 1642 CSPYLGSYSPQSQPMDLYRYPSQDPLSK-LSLPPIHTLYQPRFGNSQSFTSKYLG----- 1695
L Q D + QD +++ LS PP Q R + T++Y G
Sbjct: 769 QQLLL----QQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTI 824
Query: 1696 --YGNQNMQGDGFSSCTIRPN-----VHHVGKLPPYPTHEMDGHFMGATSRLPPNLSNPN 1748
NQ + + + PN H ++P T + MG LP N N
Sbjct: 825 SLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQN---MGMYGNLPCNQPN-- 879
Query: 1749 MDYKNGEHHSPSHIIHNYSAAPGMFNSSLHALHLQNKENDMLSHTANGLSKMLPAL---N 1805
YS GM + L Q +L++ N + P L N
Sbjct: 880 ----------------TYSVTSGM-----NQLTQQRNPKQLLANQNNPMMPRPPTLGPSN 918
Query: 1806 HDRTACVQGGLHKLSDANGQEKQP 1829
++ A G S N Q+ +P
Sbjct: 919 NNNVATFGAG----SVGNSQQLRP 938
Score = 41.2 bits (95), Expect = 0.010
Identities = 24/98 (24%), Positives = 41/98 (41%)
Query: 1483 ENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQ 1542
+ + ++++ + +Q + Q +Q + + S QQ QQ + Q Q QQQQ
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
Query: 1543 RPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYP 1580
+ QQQQ Q + +S +P SP P
Sbjct: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLP 685
Score = 39.7 bits (91), Expect = 0.030
Identities = 37/146 (25%), Positives = 55/146 (37%), Gaps = 7/146 (4%)
Query: 608 NSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDH 667
N MP LP Q + + Q Q + Q Q Q Q Q Q+ Q S +
Sbjct: 568 NQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQ 627
Query: 668 LPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASE------TEPFSNSHL-LQ 720
+ S+ + QQ+ Q ++ +Q Q +S+ ++P S L LQ
Sbjct: 628 QQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ 687
Query: 721 HKPHKQAAQTQPSQSSHLPQNQQQQQ 746
K Q Q QP +QQQ+Q
Sbjct: 688 QKLLLQQMQNQPIAGMGYQVSQQQRQ 713
Score = 38.5 bits (88), Expect = 0.067
Identities = 47/239 (19%), Positives = 87/239 (36%), Gaps = 11/239 (4%)
Query: 713 FSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE 772
F++ Q P +Q +PS + Q QQQQQ+ Q + +++ Q Q QQ++
Sbjct: 562 FNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 621
Query: 773 GSFFGQTKVEE--CFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKI 830
S Q + ++ + Q + + + Q ++ Q + +S +Q++ S
Sbjct: 622 SSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLR 681
Query: 831 QVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQE----- 885
L+ + + Q + ++ Q N P + C
Sbjct: 682 SPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPS-PNPCSNPNTGSG 740
Query: 886 --QEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPP 942
Q+S L G K Q +Q QL Q+ ++ + + P DQ H PP
Sbjct: 741 YMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAP-QDQINRHLSRPP 798
Score = 35.8 bits (81), Expect = 0.43
Identities = 53/237 (22%), Positives = 87/237 (36%), Gaps = 29/237 (12%)
Query: 562 PGWIELK-APRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGG---LPR 617
P W E+ A + Q ++ +++ Q+QP + + S G S P G +P
Sbjct: 425 PSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSS--AGPSPGPFGQEKIPS 482
Query: 618 QAYTQKTTQLEHKSQMYQVEMNQGQSQ---------------GTVDQHLQFQKPSHQVHF 662
++ Q+T + S M V GQS+ G +D +Q + F
Sbjct: 483 PSFGQQTFSPQ-SSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSF 541
Query: 663 SKTDHLPKAHVQSLCGTRFHFQQ-RADSQTEKLMSPVLKQHL------NQQASETEPFSN 715
H Q FHF +A+ Q ++ K L QQ + +
Sbjct: 542 INNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQ 601
Query: 716 SHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE 772
Q + +Q Q Q Q S + QQQQQ+ I +++ Q Q QQ++
Sbjct: 602 QQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658
Score = 35.4 bits (80), Expect = 0.56
Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 12/84 (14%)
Query: 1484 NSSNKNEKEKSA-PSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQ 1542
NS N++ S PS+ K + LL + QQ QQ Q Q+Q Q QQQQ
Sbjct: 563 NSDQANQQMPSVLPSQNKPS-----------LLHYTQQQQQQQQQQQQQQQQQQQQQQQQ 611
Query: 1543 RPQQQQPHHPQTESVNSYSASGST 1566
+ QQQQ + S S+
Sbjct: 612 QQQQQQQQQQSSISAQQQQQQQSS 635
Score = 35.4 bits (80), Expect = 0.56
Identities = 22/97 (22%), Positives = 39/97 (40%)
Query: 1478 KLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQ 1537
K S L + + ++++ + +Q + Q +Q + + + QQ Q Q
Sbjct: 580 KPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQ 639
Query: 1538 PQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPN 1574
QQQQ+ QQQQ Q + S+ P P+
Sbjct: 640 QQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPS 676
Score = 35.0 bits (79), Expect = 0.74
Identities = 27/118 (22%), Positives = 47/118 (39%)
Query: 653 FQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEP 712
F S Q + LP + SL QQ+ Q ++ +Q QQ + +
Sbjct: 560 FHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 619
Query: 713 FSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQ 770
+S Q + +Q++ + Q Q QQQQQ+ Q + +++ Q P + Q
Sbjct: 620 QQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQ 677
Score = 34.3 bits (77), Expect = 1.3
Identities = 30/154 (19%), Positives = 66/154 (42%), Gaps = 3/154 (1%)
Query: 1433 EAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKE 1492
+ Q+++++ Q +++ + + +Q++ ++ +A ++ + + +++
Sbjct: 596 QQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQ 655
Query: 1493 KSAPSRTKQTENASQAKQLAELLRLSGPV-MQQSQQPQPLQKQPPQPQQQQRPQQQQPHH 1551
+ + +Q ++ A+ L L P+ +QQ Q +Q QP Q QQQ+
Sbjct: 656 QQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQ 715
Query: 1552 PQTESVNSYSASGSTNPYMRRPNPVSPYPNSSHT 1585
N+ S S NP PN S Y NS +
Sbjct: 716 HSVVGQNT-GPSPSPNP-CSNPNTGSGYMNSQQS 747
>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
sapiens]
Length = 3549
Score = 54.7 bits (130), Expect = 9e-07
Identities = 98/469 (20%), Positives = 164/469 (34%), Gaps = 77/469 (16%)
Query: 398 PPPPSQ------LLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKI 451
PPPPS L PPPPL P+ S + E +P + K
Sbjct: 2296 PPPPSNASSEIEFPLPPPPPLMMFPEKNGFLPSLSTEKIKAEFESFPGLPLPPPPVDEKS 2355
Query: 452 EGK-------PEAPPSQSPNPSTHVCSPSP---------MLSERPQNNCVN-RNDIQTAG 494
E + P PP+ S P+ + S +P S++ +N N + I T
Sbjct: 2356 ERESSSMFLPPPPPPTPSQKPAHLLSSSAPEKHSGDFMQQYSQKEASNSQNSQAKIITGK 2415
Query: 495 TMTVPLCSEKTRPMSEHLKHNPPIFGSSGELQDN-----CQQLMRNKEQEILKGRDKEQT 549
T +P + + +H+K N F EL + C+ +++++ E T
Sbjct: 2416 TGVLPPPTLPKPKLPKHIKDNKNDFSPKVELATSLSDMECKITTSKDQKKVMVMTSSEHT 2475
Query: 550 RDLVPPTQHYLKPGWIELKAPRFHQAE--SH------LKRNEASLPSILQYQ-PNLSNQM 600
Q+ + E K A SH R + P I + P S Q
Sbjct: 2476 E----TKQNVISKSLDERKQLSIDSANCLSHTVPGTSAPRKKQIAPLIKSHSFPESSGQQ 2531
Query: 601 TSKQYTGNSNMPGGLPRQAYTQKTTQLE---HKSQMYQVEMNQGQSQ--GTVDQHLQFQK 655
K Y P + + Y Q+ ++E +S Y + Q Q+Q V++ + QK
Sbjct: 2532 NPKPYMRKFKTPLMIAEEKYRQQKEEIEKQKQESSYYNIVKTQSQNQHITEVEKEMPLQK 2591
Query: 656 PSHQVHFSKTD-------------------------HLPKAHVQSLCGTRFHFQQRADSQ 690
+ +V S D L +++ R H A
Sbjct: 2592 TNEEVSLSGIDSECTVVQPSPGSQSNARILGVCSDNQLSTTSPETVAAKRLHHVLAASED 2651
Query: 691 TEKLMSPVLKQHLN-QQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQ 749
+K+ VL+ + Q+ SH Q +Q Q + + HLPQ++ +
Sbjct: 2652 KDKMKKEVLQSSRDIMQSKSACEIKQSH--QECSTQQTQQKKYLEQLHLPQSKPISPNFK 2709
Query: 750 IKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFE 798
+K + L T H + D E S Q++++ + QY K+ + E
Sbjct: 2710 VKTIK--LPTLDHTLNETDHSYE-SHKQQSEIDVQTFTKKQYLKTKKTE 2755
Score = 34.3 bits (77), Expect = 1.3
Identities = 108/565 (19%), Positives = 193/565 (34%), Gaps = 79/565 (13%)
Query: 457 APPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPMSEHLKHNP 516
+P SQS VCS + + + P+ R A + +K + E L+ +
Sbjct: 2611 SPGSQSNARILGVCSDNQLSTTSPETVAAKRLHHVLAAS------EDKDKMKKEVLQSSR 2664
Query: 517 PIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRFHQAE 576
I S C+ ++E + + K+ L P + P + ++K + +
Sbjct: 2665 DIMQSKSA----CEIKQSHQECSTQQTQQKKYLEQLHLPQSKPISPNF-KVKTIKLPTLD 2719
Query: 577 SHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQV 636
L + S S Q T KQY T+ +T+ HK
Sbjct: 2720 HTLNETDHSYESHKQQSEIDVQTFTKKQYLKTKK----------TEASTECSHK------ 2763
Query: 637 EMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHF---QQRADSQTEK 693
Q ++H Q K +V T LP +Q + +QR S +++
Sbjct: 2764 -------QSLAERHYQLPKKEKRV----TVQLPTESIQKNQEDKLKMVPRKQREFSGSDR 2812
Query: 694 LMSPVLKQHLNQQAS----ETEPFSNSHLLQHKPHKQAAQT--QPSQSSHLPQNQQQQQK 747
P ++ NQ S + E +H +K A + Q +HL Q Q+
Sbjct: 2813 GKLPGSEEK-NQGPSMIGRKEERLITERKHEHLKNKSAPKVVKQKVIDAHLDSQTQNFQQ 2871
Query: 748 LQIKNKEEILQTFPHPQSNNDQQ----------REGSFFGQTK--VEECFHGENQYSKSS 795
QI+ E + PQ N Q +E F TK +E ++ +S
Sbjct: 2872 TQIQTAESKAEHKKLPQPYNSLQEEKCLEVKGIQEKQVFSNTKDSKQEITQNKSFFSSVK 2931
Query: 796 EFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQTTHPELFA 855
E + + + L V+ + +R Q + S + + + + + T L +
Sbjct: 2932 ESQRDDGKGALNIVEFLRKREE--LQQILSRVKQFEAEPNKSGLKTFQTLLNTIPGWLIS 2989
Query: 856 GNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQD--MSGQQAAQ 913
+K + H+ N K+++ H K+Q +L Y+N Q MS +
Sbjct: 2990 EDKREYAVHIAMENNLEKVKEEITH-------IKTQAEDMLVSYENIIQTAMMSSKTGKP 3042
Query: 914 LAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESC 973
+ L + V V +++ K ++ Q Q T
Sbjct: 3043 GNKPTSLDETSSKVSNVHVSNNKNSEQKENKIAKEKTV--------QHQVAAHHEATVRS 3094
Query: 974 HSQMHRPIKVEPGCKPHACMHTAPP 998
H + H+ IK++ P + T PP
Sbjct: 3095 HVKTHQEIKLDDSNIPPPSLKTRPP 3119
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 53.1 bits (126), Expect = 3e-06
Identities = 68/294 (23%), Positives = 105/294 (35%), Gaps = 63/294 (21%)
Query: 737 HLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSE 796
++ N QQ + N ILQT P N +QQ S G T + + +
Sbjct: 340 NITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTP--- 396
Query: 797 FETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENK--EQTTHPELF 854
ETH +Q + Q ++ P ++Q +S+ +Q HP
Sbjct: 397 -ETHMLQQQQQAQQQ--QQQHPVLHLQPQQIMQLQ---QQQQQQISQQPYPQQPPHPFSQ 450
Query: 855 AGNKTQNLHHMQY------FPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQ-DMS 907
+ Q H Q+ FP + LHR Q+ + QQ ++ Q + Q +
Sbjct: 451 QQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQ 510
Query: 908 GQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQQ 967
QQ AQL QQ LLQ+Q+QQQ QQ
Sbjct: 511 QQQLAQLQQQH------------------------------------SLLQQQQQQQIQQ 534
Query: 968 PQTESCHSQMHRPIKVEPGCKPH------ACMHTAPPENKTWKKVTKQENPPAS 1015
Q + H Q + +++ PH A H PP+ ++ +Q+ PP S
Sbjct: 535 QQLQRMHQQQQQQ-QMQSQTAPHLSQTSQALQHQVPPQQPPQQQ--QQQQPPPS 585
Score = 49.3 bits (116), Expect = 4e-05
Identities = 105/443 (23%), Positives = 152/443 (34%), Gaps = 72/443 (16%)
Query: 337 ENNIQGTTKLASGEEFCSGSSSNLQAPGGSSERYLKQNEMNGAYFKQSSVFTKDSFSATT 396
EN Q + S +E S +SS +P G + K N K +F S S+
Sbjct: 202 ENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKS---KGELMFDDSSDSS-- 256
Query: 397 TPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNG---GVLEEHHHYPNQSNTTLLREVKIEG 453
P + L+ P +VPQL + + G G++ + P L EV+
Sbjct: 257 --PEKQERNLNWTPA--EVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNL 312
Query: 454 KPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPMS-EHL 512
QS S + + SP + R N N DIQ + RP + H+
Sbjct: 313 MAAGQNLQSSERSEMIATWSPAV--RTLRNITNNADIQ-----------QMNRPSNVAHI 359
Query: 513 KHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAPRF 572
+ E Q N Q +L + K V P H L
Sbjct: 360 LQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVK------VTPETHML------------ 401
Query: 573 HQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQ 632
Q + ++ + P +L QP Q+ +Q S P Y Q Q H
Sbjct: 402 -QQQQQAQQQQQQHP-VLHLQPQQIMQLQQQQQQQISQQP-------YPQ---QPPHPFS 449
Query: 633 MYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTE 692
Q + Q Q LQF P Q+H + H P+ +Q FQQ+ Q +
Sbjct: 450 QQQQQQQQAHPHQFSQQQLQF--PQQQLHPPQQLHRPQQQLQP-------FQQQHALQQQ 500
Query: 693 KLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKN 752
L+QH QQ + H L + +Q Q Q Q H Q QQQ Q +
Sbjct: 501 ---FHQLQQHQLQQ-QQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPH 556
Query: 753 KEEILQTFPH---PQSNNDQQRE 772
+ Q H PQ QQ++
Sbjct: 557 LSQTSQALQHQVPPQQPPQQQQQ 579
Score = 44.3 bits (103), Expect = 0.001
Identities = 55/257 (21%), Positives = 96/257 (37%), Gaps = 40/257 (15%)
Query: 647 VDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVL----KQH 702
V+ Q ++ V FS+ P+ H+ QQ+ +Q ++ PVL +Q
Sbjct: 374 VNHSQQGHTNANAVLFSQVKVTPETHM---------LQQQQQAQQQQQQHPVLHLQPQQI 424
Query: 703 LNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPH 762
+ Q + + S Q PH + Q Q Q +H +Q QQ+LQ + Q P
Sbjct: 425 MQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAH--PHQFSQQQLQFPQQ----QLHPP 478
Query: 763 PQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFETHNVQMGLEEVQNINRRNSPYSQT 822
Q + QQ+ F Q +++ FH + + H +Q Q + + +S
Sbjct: 479 QQLHRPQQQLQPFQQQHALQQQFH---------QLQQHQLQQ-----QQLAQLQQQHSLL 524
Query: 823 MKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRC 882
+ +IQ H + ++ + +Q L H +P Q +
Sbjct: 525 QQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQ-------VPPQQPPQQQ 577
Query: 883 FQEQEQKSQQASVLQGY 899
Q+Q S Q L G+
Sbjct: 578 QQQQPPPSPQQHQLFGH 594
Score = 40.4 bits (93), Expect = 0.018
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 6/124 (4%)
Query: 1431 SVEAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNE 1490
+ + Q+ + S +L + + L + V +Q A A S ++ + +
Sbjct: 344 NADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNAN---AVLFSQVKVTPETHM 400
Query: 1491 KEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQ-SQQPQPLQKQPPQPQQQQRPQQQQP 1549
++ ++ +Q ++ Q ++++L QQ SQQP P +QPP P QQ+ QQQQ
Sbjct: 401 LQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYP--QQPPHPFSQQQQQQQQA 458
Query: 1550 HHPQ 1553
H Q
Sbjct: 459 HPHQ 462
Score = 38.9 bits (89), Expect = 0.051
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 1468 KLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQ 1527
+L+ + ++L+ L+ + ++++ + +Q + Q +Q ++ + P + Q+ Q
Sbjct: 503 QLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQ 562
Query: 1528 PQPLQKQPPQPQQQQRPQQQQPHHPQ 1553
Q P QP QQQ+ QQQ P PQ
Sbjct: 563 ALQHQVPPQQPPQQQQ-QQQPPPSPQ 587
Score = 38.9 bits (89), Expect = 0.051
Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
Query: 1507 QAKQLAELLRLSGPVMQQSQQP---QPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSAS 1563
Q +QLA+L + + QQ QQ Q LQ+ Q QQQQ Q PH QT +
Sbjct: 510 QQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVP 569
Query: 1564 GSTNPYMRRPNPVSPYP 1580
P ++ P P
Sbjct: 570 PQQPPQQQQQQQPPPSP 586
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 50.8 bits (120), Expect = 1e-05
Identities = 38/159 (23%), Positives = 62/159 (38%), Gaps = 19/159 (11%)
Query: 609 SNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHL 668
+ M G P TQ + ++ + Q++ Q Q Q + Q Q Q HQ+H +
Sbjct: 416 TTMVGSAPS---TQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQM 472
Query: 669 PKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAA 728
+ H Q H QQ Q + L + +Q L QQ + +QH+
Sbjct: 473 QQQHFQ------HHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPR 526
Query: 729 QTQPSQS----------SHLPQNQQQQQKLQIKNKEEIL 757
Q P S S P +QQ Q ++Q + + ++L
Sbjct: 527 QHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVL 565
Score = 35.4 bits (80), Expect = 0.56
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 699 LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQ--SSHLPQN-QQQQQKLQIKNKEE 755
L+Q QQ + + L QH+ H+Q Q Q H+ Q+ QQQQQ LQ + ++
Sbjct: 440 LQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQ 499
Query: 756 ILQ 758
LQ
Sbjct: 500 QLQ 502
Score = 35.4 bits (80), Expect = 0.56
Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 5/129 (3%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+Q+ QQ + Q QQ Q QQ++ H+ + Q Q Q
Sbjct: 441 QQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQ--HLQQQQQHLQQQINQ 498
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQP---QTESCHSQMHRPIKVEPGCKPHACMHTAPPEN 1000
+ Q+ R L Q Q Q QP Q SQ+ PI +P + H + ++
Sbjct: 499 QQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQS 558
Query: 1001 KTWKKVTKQ 1009
+T +V Q
Sbjct: 559 QTQTQVLSQ 567
Score = 33.1 bits (74), Expect = 2.8
Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 12/148 (8%)
Query: 938 TQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAP 997
TQ P TQ+H Q+Q+QQ Q Q + QMH+ I+ + + H H
Sbjct: 425 TQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQ-QQHFQHHMQQ 483
Query: 998 PENKTWKKVTKQENPPASCDNVQQKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVE 1057
+ + + +Q N +QQ+ ++ + QH++ S H V +
Sbjct: 484 HLQQQQQHLQQQINQQQLQQQLQQRLQLQQL-QHMQHQSQPSPRQH--------SPVASQ 534
Query: 1058 MSGPVTVLTRQTTAAELDSHTPALEQQT 1085
++ P+ + A++ H ++ QT
Sbjct: 535 ITSPIPAIGSPQPASQ--QHQSQIQSQT 560
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 727 AAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE--GSFFGQTKVEEC 784
+ QTQ Q Q QQQQQ++Q ++++ Q H Q Q++ Q ++
Sbjct: 430 SVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQ 489
Query: 785 FHGENQYSKSSEFETHNVQMGLEEVQNINRRNSP 818
H + Q ++ + ++ L+++Q++ ++ P
Sbjct: 490 QHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQP 523
Score = 32.3 bits (72), Expect = 4.8
Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 12/157 (7%)
Query: 817 SPYSQTMKSSACKIQVSCSNNT--HLVSENKEQTTHPELFAGNKTQNL--HHMQYFPNNV 872
S TM SA QVS S T H + ++Q + + Q L H M
Sbjct: 412 SSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQ 471
Query: 873 IPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPD 932
+ +Q H Q +Q+ Q + NQ QQ Q Q + L H P P
Sbjct: 472 MQQQHFQHHMQQHLQQQQQHLQ-----QQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPR 526
Query: 933 QG---GSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQ 966
Q S +P A + H Q Q Q QTQ
Sbjct: 527 QHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQ 563
Score = 32.3 bits (72), Expect = 4.8
Identities = 28/76 (36%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 1522 MQQSQQ--PQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPV--S 1577
+QQ QQ Q + +Q Q Q QQR Q QQ H Q +S S + P P S
Sbjct: 485 LQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGS 544
Query: 1578 PYPNS-SHTSDIYGST 1592
P P S H S I T
Sbjct: 545 PQPASQQHQSQIQSQT 560
Score = 32.0 bits (71), Expect = 6.2
Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
Query: 1494 SAPSR--TKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHH 1551
SAPS + + QL + + MQQ QQ Q Q Q Q QQQ QQ HH
Sbjct: 421 SAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHH 480
Query: 1552 PQ 1553
Q
Sbjct: 481 MQ 482
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 50.8 bits (120), Expect = 1e-05
Identities = 38/159 (23%), Positives = 62/159 (38%), Gaps = 19/159 (11%)
Query: 609 SNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHL 668
+ M G P TQ + ++ + Q++ Q Q Q + Q Q Q HQ+H +
Sbjct: 421 TTMVGSAPS---TQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQM 477
Query: 669 PKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAA 728
+ H Q H QQ Q + L + +Q L QQ + +QH+
Sbjct: 478 QQQHFQ------HHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPR 531
Query: 729 QTQPSQS----------SHLPQNQQQQQKLQIKNKEEIL 757
Q P S S P +QQ Q ++Q + + ++L
Sbjct: 532 QHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQVL 570
Score = 35.4 bits (80), Expect = 0.56
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 699 LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQ--SSHLPQN-QQQQQKLQIKNKEE 755
L+Q QQ + + L QH+ H+Q Q Q H+ Q+ QQQQQ LQ + ++
Sbjct: 445 LQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQ 504
Query: 756 ILQ 758
LQ
Sbjct: 505 QLQ 507
Score = 35.4 bits (80), Expect = 0.56
Identities = 33/129 (25%), Positives = 51/129 (39%), Gaps = 5/129 (3%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+Q+ QQ + Q QQ Q QQ++ H+ + Q Q Q
Sbjct: 446 QQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQ--HLQQQQQHLQQQINQ 503
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQP---QTESCHSQMHRPIKVEPGCKPHACMHTAPPEN 1000
+ Q+ R L Q Q Q QP Q SQ+ PI +P + H + ++
Sbjct: 504 QQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQPASQQHQSQIQS 563
Query: 1001 KTWKKVTKQ 1009
+T +V Q
Sbjct: 564 QTQTQVLSQ 572
Score = 33.1 bits (74), Expect = 2.8
Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 12/148 (8%)
Query: 938 TQTPPQKDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAP 997
TQ P TQ+H Q+Q+QQ Q Q + QMH+ I+ + + H H
Sbjct: 430 TQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQ-QQHFQHHMQQ 488
Query: 998 PENKTWKKVTKQENPPASCDNVQQKSIIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVE 1057
+ + + +Q N +QQ+ ++ + QH++ S H V +
Sbjct: 489 HLQQQQQHLQQQINQQQLQQQLQQRLQLQQL-QHMQHQSQPSPRQH--------SPVASQ 539
Query: 1058 MSGPVTVLTRQTTAAELDSHTPALEQQT 1085
++ P+ + A++ H ++ QT
Sbjct: 540 ITSPIPAIGSPQPASQ--QHQSQIQSQT 565
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/94 (22%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 727 AAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE--GSFFGQTKVEEC 784
+ QTQ Q Q QQQQQ++Q ++++ Q H Q Q++ Q ++
Sbjct: 435 SVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQ 494
Query: 785 FHGENQYSKSSEFETHNVQMGLEEVQNINRRNSP 818
H + Q ++ + ++ L+++Q++ ++ P
Sbjct: 495 QHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQP 528
Score = 32.3 bits (72), Expect = 4.8
Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 12/157 (7%)
Query: 817 SPYSQTMKSSACKIQVSCSNNT--HLVSENKEQTTHPELFAGNKTQNL--HHMQYFPNNV 872
S TM SA QVS S T H + ++Q + + Q L H M
Sbjct: 417 SSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQ 476
Query: 873 IPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPD 932
+ +Q H Q +Q+ Q + NQ QQ Q Q + L H P P
Sbjct: 477 MQQQHFQHHMQQHLQQQQQHLQ-----QQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPR 531
Query: 933 QG---GSHTQTPPQKDTQKHAALRWHLLQKQEQQQTQ 966
Q S +P A + H Q Q Q QTQ
Sbjct: 532 QHSPVASQITSPIPAIGSPQPASQQHQSQIQSQTQTQ 568
Score = 32.3 bits (72), Expect = 4.8
Identities = 28/76 (36%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 1522 MQQSQQ--PQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPV--S 1577
+QQ QQ Q + +Q Q Q QQR Q QQ H Q +S S + P P S
Sbjct: 490 LQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGS 549
Query: 1578 PYPNS-SHTSDIYGST 1592
P P S H S I T
Sbjct: 550 PQPASQQHQSQIQSQT 565
Score = 32.0 bits (71), Expect = 6.2
Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
Query: 1494 SAPSR--TKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHH 1551
SAPS + + QL + + MQQ QQ Q Q Q Q QQQ QQ HH
Sbjct: 426 SAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHH 485
Query: 1552 PQ 1553
Q
Sbjct: 486 MQ 487
>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
Length = 521
Score = 50.8 bits (120), Expect = 1e-05
Identities = 36/108 (33%), Positives = 48/108 (44%), Gaps = 22/108 (20%)
Query: 1523 QQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSAS------GSTNPYMRRPNPV 1576
QQ QQPQP Q+QPPQPQQ Q Q QQP P + + S GS P++ V
Sbjct: 371 QQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTV 430
Query: 1577 SPYPNSSHTSD----------------IYGSTSPMNFYSTSSQAAGSY 1608
+ +P+ S S+ ++ + P SS A GSY
Sbjct: 431 TTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSY 478
Score = 38.9 bits (89), Expect = 0.051
Identities = 26/61 (42%), Positives = 29/61 (47%), Gaps = 4/61 (6%)
Query: 1523 QQSQQPQPLQKQPPQPQQQQ--RPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYP 1580
QQ QQPQ Q Q PQP QQQ +PQQ QP PQ S + P SP P
Sbjct: 365 QQPQQPQ--QPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLP 422
Query: 1581 N 1581
+
Sbjct: 423 H 423
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 50.4 bits (119), Expect = 2e-05
Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 32/199 (16%)
Query: 1505 ASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVN------ 1558
A Q KQ+A + +MQQ QQ Q +Q Q QQQQ+ QQQQ H QT + +
Sbjct: 465 AEQLKQMAAQQQQRAKLMQQKQQQQ---QQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPS 521
Query: 1559 -----SYSASGSTNPYM-----RRPNPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGSY 1608
+++A +P M NP+ P ++ + P N + +Q +
Sbjct: 522 SPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNL 581
Query: 1609 LNSSNPMNPYPGLLNQNTQYPSYQCNGNLS-----------VDNCSPYLGSYSPQSQPMD 1657
+N +N +L P N +LS + PY+ Q Q
Sbjct: 582 --GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQ 639
Query: 1658 LYRYPSQDPLSKLSLPPIH 1676
+ Q P +L P H
Sbjct: 640 QQQQQQQPPPPQLQAPRAH 658
Score = 33.1 bits (74), Expect = 2.8
Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 13/99 (13%)
Query: 947 QKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRP-----IKVEPGCKPHACMHTAPPENK 1001
Q+ A L Q+Q+QQQ QQ Q + Q H + P P+ TA N
Sbjct: 476 QQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNS 535
Query: 1002 --TWKKVTKQENP--PASCDNVQQKSIIETMEQHLKQFH 1036
+ + +NP P +N+Q+ TM +L Q H
Sbjct: 536 PMMYPQAFNNQNPIVPPMANNLQK----TTMNNYLPQNH 570
Score = 32.0 bits (71), Expect = 6.2
Identities = 72/363 (19%), Positives = 127/363 (34%), Gaps = 45/363 (12%)
Query: 591 QYQPNLSNQMTSKQYTGNSN--MPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVD 648
Q Q Q +Q++ ++ P G P Y T + S M + Q+
Sbjct: 493 QQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPP 552
Query: 649 QHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQAS 708
QK + ++LP+ H+ + QQ + T L KQH
Sbjct: 553 MANNLQKTT------MNNYLPQNHMNMIN------QQPNNLGTNSLN----KQHNILTYG 596
Query: 709 ETEPFS--NSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQ-- 764
T+P + N+ L Q A P+++ +P QQQQQ+ Q + +++ Q P PQ
Sbjct: 597 NTKPLTHFNADLSQRMTPPVA---NPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQ 653
Query: 765 -----SNNDQQR-----EGSFFGQTKVEECF--HGENQYSKSSEFETHNVQMGLEE---- 808
+ DQ+R + Q HG+ Q+ T +Q +
Sbjct: 654 APRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGG 713
Query: 809 -VQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQTTHPELFAGNKTQNLHHMQY 867
V + + + +A Q+ L+ + K+Q + + Q + Q
Sbjct: 714 MVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQ 773
Query: 868 FPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANV 927
+ +P+Q H Q QQ + QG + Q A Q + L+ +A +
Sbjct: 774 LQQSHLPRQ---HLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGM 830
Query: 928 FPV 930
+
Sbjct: 831 MGI 833
Score = 31.6 bits (70), Expect = 8.2
Identities = 42/185 (22%), Positives = 72/185 (38%), Gaps = 14/185 (7%)
Query: 1520 PVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSA-SGSTNPYMRRPNPVSP 1578
P Q Q Q++ QQ+Q+ QQQQ Q + S T+ + P SP
Sbjct: 464 PAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSP 523
Query: 1579 YPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLS 1638
Y ++ T++ SPM + N+ NP+ P Q T +Y +++
Sbjct: 524 Y-GAAFTAE--KPNSPMMYPQA--------FNNQNPIVPPMANNLQKTTMNNYLPQNHMN 572
Query: 1639 VDNCSP-YLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFGNSQSFTSKYLGYG 1697
+ N P LG+ S Q ++ Y + PL+ + + P +++ Y+
Sbjct: 573 MINQQPNNLGTNSLNKQ-HNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQ 631
Query: 1698 NQNMQ 1702
Q Q
Sbjct: 632 QQQQQ 636
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 48.9 bits (115), Expect = 5e-05
Identities = 65/314 (20%), Positives = 112/314 (35%), Gaps = 27/314 (8%)
Query: 1473 KAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQ 1532
K +A+ + SL+ + + ++ + +Q + Q +QL + QQ QQ Q Q
Sbjct: 3888 KLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQ 3947
Query: 1533 KQPPQPQQQQRPQQQQPHHPQTESVNSYSASGST----NPYMRRPNPVSPYPNSSHTSDI 1588
Q Q Q QQ+ QQQQ Q + + +P ++ V+ P
Sbjct: 3948 LQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM------ 4001
Query: 1589 YGSTSPMNFYSTSSQAAGSYLNSSNPMNPY-PGLLNQNTQYPSYQCNGNLSVDNCSPYLG 1647
P+ +S+ + L + N P + ++ T+ PS G L++ +
Sbjct: 4002 --PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059
Query: 1648 --------SYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFGNSQSFTSKYLGYGNQ 1699
S S SQ + + P P S PP+ Q + S T+ G G+
Sbjct: 4060 TEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTA---GGGSH 4116
Query: 1700 NMQGDGFSSCTIRPNVHHVGKLPPYPTHEMDGHF-MGATSRLPPNLSNPNMDYKNGEHHS 1758
G G SS +V H+ P + G P L P + +
Sbjct: 4117 GQLGSGSSS--EASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPK 4174
Query: 1759 PSHIIHNYSAAPGM 1772
P ++ + PG+
Sbjct: 4175 PGPVLQSGQGLPGV 4188
Score = 40.0 bits (92), Expect = 0.023
Identities = 37/144 (25%), Positives = 56/144 (38%), Gaps = 15/144 (10%)
Query: 635 QVEMNQGQSQGTVD--QHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTE 692
Q + Q Q QG++ HLQ SH PK Q + + QQ+ Q +
Sbjct: 3858 QQQQQQHQQQGSMAGLSHLQQSLMSHSGQ-------PKLSAQPMGSLQQLQQQQQLQQQQ 3910
Query: 693 KLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQIKN 752
+L +Q QQ + + Q +Q Q Q Q Q QQQQQ+ Q +
Sbjct: 3911 QLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQ 3970
Query: 753 KEEIL------QTFPHPQSNNDQQ 770
+++ + +T PQ QQ
Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQ 3994
Score = 37.7 bits (86), Expect = 0.11
Identities = 53/214 (24%), Positives = 77/214 (35%), Gaps = 32/214 (14%)
Query: 1470 EAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQ 1529
E++KA K L SS P ++ S L L + V + P+
Sbjct: 2280 ESRKALEVKKEELGASS-----PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPR 2334
Query: 1530 PLQKQPPQPQQQQRPQQ---------QQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYP 1580
Q +P P RPQ+ P HP SY+ + P RP P P P
Sbjct: 2335 ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP--PPP 2392
Query: 1581 NSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSVD 1640
S + + P + +S + S +S +P+ P P L+ PS
Sbjct: 2393 ES--CCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP--LSAEAFCPS---------- 2438
Query: 1641 NCSPYLGSYSPQSQPMDLYRYPSQDPLSKLSLPP 1674
+P S P S+P R S+DP + L PP
Sbjct: 2439 PVTPRFQSPDPYSRPPS--RPQSRDPFAPLHKPP 2470
Score = 35.4 bits (80), Expect = 0.56
Identities = 23/102 (22%), Positives = 43/102 (42%)
Query: 1456 MLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELL 1515
++ + T +Q++ + + ++ L + P + Q + Q Q + L
Sbjct: 3847 LMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQL 3906
Query: 1516 RLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESV 1557
+ + QQ QQ Q+Q Q Q QQ+ QQQQ Q + +
Sbjct: 3907 QQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQL 3948
Score = 35.0 bits (79), Expect = 0.74
Identities = 37/169 (21%), Positives = 62/169 (36%), Gaps = 6/169 (3%)
Query: 612 PGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKA 671
P G RQ ++ L Q + G T Q Q Q+ Q + HL ++
Sbjct: 3820 PQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQS 3879
Query: 672 HVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQ 731
+ S G Q + +Q + + +Q QQ + + L Q + +Q Q
Sbjct: 3880 -LMSHSG-----QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQ 3933
Query: 732 PSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTK 780
Q L Q QQQQ + Q + ++ Q QQ++ Q++
Sbjct: 3934 QQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSR 3982
Score = 33.5 bits (75), Expect = 2.1
Identities = 40/170 (23%), Positives = 65/170 (38%), Gaps = 18/170 (10%)
Query: 635 QVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHV----QSLCGTRF----HFQQR 686
QV + Q Q G + Q P QV +++ L + Q L G R QQ+
Sbjct: 3806 QVAVLQQQHPGALGP----QGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQ 3861
Query: 687 ADSQTEKLMSPV------LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQ 740
Q + M+ + L H Q +P + LQ + Q Q Q Q
Sbjct: 3862 QQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQ 3921
Query: 741 NQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQ 790
QQQ Q+ Q++ +++ Q Q QQ++ Q + ++ F + Q
Sbjct: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ 3971
Score = 32.3 bits (72), Expect = 4.8
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 19/94 (20%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+Q QQ + Q + + Q Q QL QQ+ Q Q
Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQ-------------------QQQLQ 3941
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQM 977
+ Q+ + LQ+Q+QQQ QQ Q + QM
Sbjct: 3942 QQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQM 3975
Score = 31.6 bits (70), Expect = 8.2
Identities = 39/129 (30%), Positives = 53/129 (41%), Gaps = 28/129 (21%)
Query: 397 TPPPPSQLLLSPPP------PLPQVPQL--PSEGKSTLNGGVLEEHHHYPNQSNTTLLRE 448
T PPP LSPPP PLP+ L P E +S L+ E P +S+
Sbjct: 458 TSPPPEASRLSPPPEELPASPLPEALHLSRPLE-ESPLSPPPEESPLSPPPESSPF---- 512
Query: 449 VKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPM 508
+E P +PP +SP PS + +P LS P+ A ++ P P
Sbjct: 513 SPLEESPLSPPEESP-PSPALETP---LSPPPE-----------ASPLSPPFEESPLSPP 557
Query: 509 SEHLKHNPP 517
E L +PP
Sbjct: 558 PEELPTSPP 566
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 47.8 bits (112), Expect = 1e-04
Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 13/141 (9%)
Query: 1496 PSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQ-------- 1547
P Q + A Q A+ ++ P +Q SQ P+ P QQ Q PQ
Sbjct: 357 PPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP 416
Query: 1548 QPHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNFYSTSSQAAGS 1607
QP P ++ ++ S+ + +P P+P SP P+ S + + +P NF S +
Sbjct: 417 QPGQPSSQPNSNVSSGPAPSPSSFLPSP-SPQPSQSPVT----ARTPQNFSVPSPGPLNT 471
Query: 1608 YLNSSNPMNPYPGLLNQNTQY 1628
+N S+ M+P + QY
Sbjct: 472 PVNPSSVMSPAGSSQAEEQQY 492
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 12/130 (9%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+ ++QQ+++ Q ++ Q Q Q QQ + +H N + Q Q
Sbjct: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQ---------Q 235
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTW 1003
+ Q+ A L+ LQ+Q+QQQ QQ Q + Q PI+ P +P A P+
Sbjct: 236 QQLQRIAQLQ---LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQ 292
Query: 1004 KKVTKQENPP 1013
T+ PP
Sbjct: 293 MHHTQHHQPP 302
Score = 38.1 bits (87), Expect = 0.087
Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 20/161 (12%)
Query: 617 RQAYTQKTTQLEHKSQMYQVEMN--QGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQ 674
+QA Q+ Q + + Q +Q + + Q Q Q V Q Q Q+ Q HL K H Q
Sbjct: 173 QQAALQQQQQ-QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ-----QQHLIKLHHQ 226
Query: 675 SLCGTRFHFQQRADSQTEKLMSPV-LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPS 733
+ QQ+ Q ++L L+ QQ + + LQ +P Q P
Sbjct: 227 N--------QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP---PIQQPPM 275
Query: 734 QSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGS 774
Q P +Q Q+LQ + + Q P PQ Q + S
Sbjct: 276 QQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
Score = 36.2 bits (82), Expect = 0.33
Identities = 35/147 (23%), Positives = 56/147 (38%), Gaps = 12/147 (8%)
Query: 1496 PSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTE 1555
P +++ SQA+ L + + P ++ + P +Q+ P QPQ QQ+ Q
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378
Query: 1556 SVNSYSASGSTNPYMRRPNP---------VSPYPNSSHTSDIYGSTSPMNFYSTSSQAAG 1606
S S+ P + P+P + P P S S N S + +
Sbjct: 379 VAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPS 438
Query: 1607 SYLNSSNP---MNPYPGLLNQNTQYPS 1630
S+L S +P +P QN PS
Sbjct: 439 SFLPSPSPQPSQSPVTARTPQNFSVPS 465
Score = 35.8 bits (81), Expect = 0.43
Identities = 84/432 (19%), Positives = 147/432 (34%), Gaps = 58/432 (13%)
Query: 725 KQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEEC 784
+Q Q Q Q + L Q QQQQQ+ Q + ++ +Q QQ + Q + +
Sbjct: 164 QQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKL 223
Query: 785 FHGENQYSKSSEFETHNV-QMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSE 843
H Q + + + + Q+ L++ Q ++ Q + IQ
Sbjct: 224 HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ---------QPP 274
Query: 844 NKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRN 903
++ P + Q +HH Q+ P+Q + Q Q SQ +++
Sbjct: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPV-----AQNQPSQLPP-----QSQT 324
Query: 904 QDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQ 963
Q + Q A Q Y TQ PP K + ++ +Q Q QQ
Sbjct: 325 QPLVSQAQALPGQMLY------------------TQ-PPLKFVRAPMVVQQPPVQPQVQQ 365
Query: 964 QTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQQKS 1023
Q QT + ++V P M ++P + + PP Q S
Sbjct: 366 QQTAVQTAQAAQMVAPGVQVSQSSLP---MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS 422
Query: 1024 IIETMEQHLKQFHAKSLF--------DHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELD 1075
+ S F +T ++ + V GP+ ++
Sbjct: 423 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 482
Query: 1076 SHTPALEQQTTSSEKTPTK--RTAASVLNNFIESPSKLLD-TPIKNLLDTPVKTQYDFPS 1132
+ A EQQ K +K ++N ++ + D + +K+LLD PS
Sbjct: 483 GSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTD-----PS 537
Query: 1133 CRCVEQIIEKDE 1144
RC + ++K E
Sbjct: 538 KRCPLKTLQKCE 549
Score = 35.4 bits (80), Expect = 0.56
Identities = 33/152 (21%), Positives = 57/152 (37%), Gaps = 13/152 (8%)
Query: 1465 RQRKLEAKKAAAEKLSSLENSSNKN-EKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQ 1523
+Q++L+ ++ + L L + + + ++++ R Q + Q +Q + Q
Sbjct: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQ---------Q 256
Query: 1524 QSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSS 1583
Q QQ Q LQ QPP QQ P QQ P T + P P P +
Sbjct: 257 QQQQQQALQAQPPI---QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN 313
Query: 1584 HTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPM 1615
S + + S + G L + P+
Sbjct: 314 QPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL 345
Score = 33.5 bits (75), Expect = 2.1
Identities = 28/117 (23%), Positives = 53/117 (45%), Gaps = 7/117 (5%)
Query: 1465 RQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRT------KQTENASQAKQLAELLRLS 1518
+Q++ + ++ AA + + + + ++SA + +Q + Q +Q L++L
Sbjct: 165 QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLH 224
Query: 1519 GPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNP 1575
QQ QQ Q ++ Q Q QQ+ QQQQ Q + + P M++P P
Sbjct: 225 HQNQQQIQQQQQQLQRIAQLQLQQQ-QQQQQQQQQQQQQALQAQPPIQQPPMQQPQP 280
Score = 32.0 bits (71), Expect = 6.2
Identities = 17/42 (40%), Positives = 22/42 (52%)
Query: 1515 LRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTES 1556
L+L +QQ QQ Q Q+Q QQQ+ QQQQ +S
Sbjct: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQS 194
Score = 32.0 bits (71), Expect = 6.2
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 11/111 (9%)
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQH----KPHKQAAQTQPSQSSHL- 738
QQ+ Q ++ L+Q QQ + S + Q +Q Q Q Q HL
Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLI 221
Query: 739 ---PQNQQQ--QQKLQIKNKEEI-LQTFPHPQSNNDQQREGSFFGQTKVEE 783
QNQQQ QQ+ Q++ ++ LQ Q QQ++ + Q +++
Sbjct: 222 KLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
>gi|148922920 DENN/MADD domain containing 4B [Homo sapiens]
Length = 1496
Score = 47.0 bits (110), Expect = 2e-04
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Query: 1516 RLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTN--PYMRRP 1573
+L V+ +Q QPL+++ Q QQQQ+ QQQQ Q E V+++ +GS+ PY+ RP
Sbjct: 876 KLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQ----QQEQVSAHQEAGSSQAEPYLERP 931
Query: 1574 NPVSP 1578
+P P
Sbjct: 932 SPTRP 936
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 46.2 bits (108), Expect = 3e-04
Identities = 53/197 (26%), Positives = 86/197 (43%), Gaps = 22/197 (11%)
Query: 1400 REDNREFGGKPEDEQLHVLPLYKVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAE 1459
RE +E + E EQ + K ++ +E Q+EK++ +Q + ++ + E
Sbjct: 535 RERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKE--LQKMKEQEKECELEKE 592
Query: 1460 PVKTCRQRKLEAKKAAAEKL---SSLENSSNKNEK-----------EKSAPSRTKQTENA 1505
K + K+E ++ E + ENS NK E+ EK A +TE
Sbjct: 593 REKL--EEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPE 650
Query: 1506 SQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGS 1565
S ++ +L Q+S P+ ++Q QQQ + QQQQ PQT V S +S +
Sbjct: 651 SGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQT--VPSQPSSST 708
Query: 1566 TNPYMRRP--NPVSPYP 1580
P RP P+ P+P
Sbjct: 709 VPPPPHRPLYQPMQPHP 725
Score = 38.5 bits (88), Expect = 0.067
Identities = 32/147 (21%), Positives = 66/147 (44%), Gaps = 13/147 (8%)
Query: 1411 EDEQLHVLPLYKVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCRQRKLE 1470
E E+ +L ++ ++D+F +++A+ ++ +GA Q+ + ++ + Q
Sbjct: 290 EPERPSILSASELKELDKFDNLDAEADEGWAGA-QMEVDYTEQLNFSDDD----EQGSNS 344
Query: 1471 AKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQ---- 1526
K+ +E S + +N+N+KE S TK + +A++ GP Q +
Sbjct: 345 PKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSS 404
Query: 1527 ----QPQPLQKQPPQPQQQQRPQQQQP 1549
P+ L +Q P P +Q P + P
Sbjct: 405 HLPPPPKLLAQQHPPPDRQAVPGRPGP 431
Score = 33.1 bits (74), Expect = 2.8
Identities = 31/134 (23%), Positives = 61/134 (45%), Gaps = 16/134 (11%)
Query: 1422 KVSDVDEFGSVEAQEEKKRSGAIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSS 1481
+V+D DE +++ + S A++ R + R E + QRK A AEKL
Sbjct: 437 QVADEDEIWKQRRRQQSEISAAVE-----RARKRREEEERRMEEQRKA----ACAEKLKR 487
Query: 1482 LENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQ 1541
L+ EK+ S P ++ E + ++ EL + +Q Q+ + +++ + QQ+
Sbjct: 488 LDEKLGILEKQPS-PEEIREREREKEREREKELEK------EQEQEREKEREKDRERQQE 540
Query: 1542 QRPQQQQPHHPQTE 1555
+ + ++ Q E
Sbjct: 541 KEKELEKEQEKQRE 554
Score = 33.1 bits (74), Expect = 2.8
Identities = 56/279 (20%), Positives = 99/279 (35%), Gaps = 43/279 (15%)
Query: 237 CVSIAVQKTTS-----HINAINSQATNELSCEITHPS-HTSGQINSAQTSNSELPPKPAA 290
C QKT S I+A+ SQ + + S ++H S HT ++ +P +
Sbjct: 895 CFEAPDQKTLSAPQEERISAVESQPSRKRS--VSHGSNHTQKPDEQRSEPSAGIPKVTSR 952
Query: 291 VVSEACDADDADNASKLAAMLNTCSFQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGE 350
+ + + K + + KPE++ + KS P P+ N +
Sbjct: 953 CIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEV------- 1005
Query: 351 EFCSGSSSNLQAPGGSSERYLK--QNEMNGAYFKQSSVFTKDSFSATTTPPPPSQLLLSP 408
+ ++ G + L+ + E K+ K + P + L P
Sbjct: 1006 -----NDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPP 1060
Query: 409 PPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTH 468
PPP PQ P P + +S + + E +P+ TL ++ PSQ +
Sbjct: 1061 PPPPPQ-PPAPIQPQS-VPPPIQPEAEKFPSTETATLAQK----------PSQD---TEK 1105
Query: 469 VCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRP 507
P + P VN+ TM P+ E+ +P
Sbjct: 1106 PLEPVSTVQVEPAVKTVNQQ------TMAAPVVKEEKQP 1138
Score = 32.7 bits (73), Expect = 3.7
Identities = 61/325 (18%), Positives = 115/325 (35%), Gaps = 54/325 (16%)
Query: 1436 EEKKRSGAIQVLSSFRRKVRMLAEPV--KTCRQRKLEAKKAAAEKLSSLENSSNKNEKEK 1493
EE++++ + L K+ +L + + R+R+ E ++ ++L + + E+EK
Sbjct: 474 EEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK 533
Query: 1494 SAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQ----- 1548
R +Q E + ++ E R +Q ++ + L++Q + ++ Q+ ++Q+
Sbjct: 534 D---RERQQEKEKELEKEQEKQREMEKERKQEKEKE-LERQKEKEKELQKMKEQEKECEL 589
Query: 1549 ------------PHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSSHT----SDIYGST 1592
P P E + S N + PV +S+ + + + T
Sbjct: 590 EKEREKLEEKIEPREPNLEPM--VEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHET 647
Query: 1593 SPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSVDNCSPYLGSYSPQ 1652
P + Y P P Q Q Q Q
Sbjct: 648 EPESGSQPRPAVLSGYFKQFQKSLP-PRFQRQQEQMKQQQWQ---------------QQQ 691
Query: 1653 SQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFGNSQSFTSKYLGYGNQNMQGDGFSSCTI- 1711
Q + PSQ S + PP LYQP + Q S +G+ + + + +
Sbjct: 692 QQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLAS--MGFDPRWLMMQSYMDPRMM 749
Query: 1712 --RPNVH----HVGKLPPYPTHEMD 1730
RP + H G +PP P D
Sbjct: 750 SGRPAMDIPPIHPGMIPPKPLMRRD 774
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 45.4 bits (106), Expect = 5e-04
Identities = 61/226 (26%), Positives = 94/226 (41%), Gaps = 38/226 (16%)
Query: 1496 PSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQR------PQQQQP 1549
P +++ SQA+ L + + P ++ + P +Q+ P QPQ QQ+ Q Q
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQM 378
Query: 1550 HHPQTESVNSYSASGSTNPYMRRP--NPVSPYPNSS------HTSDIYGSTSPMNFYSTS 1601
P + + A G + R P VS P+SS + + S+ PM S
Sbjct: 379 VAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPM----LS 434
Query: 1602 SQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSVDNCSPYLGSYSPQSQPMDLYRY 1661
S + G + + M P P Q Q PS Q N N+S +P S+ P P
Sbjct: 435 SPSPGQQVQTPQSMPPPPQPSPQPGQ-PSSQPNSNVS-SGPAPSPSSFLPSPSPQ----- 487
Query: 1662 PSQDPLS-----KLSLP---PIHTLYQPR-----FGNSQSFTSKYL 1694
PSQ P++ S+P P++T P G+SQ+ +YL
Sbjct: 488 PSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYL 533
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 12/130 (9%)
Query: 884 QEQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQ 943
Q+Q+ ++QQ+++ Q ++ Q Q Q QQ + +H N + Q Q
Sbjct: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQ---------Q 235
Query: 944 KDTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTW 1003
+ Q+ A L+ LQ+Q+QQQ QQ Q + Q PI+ P +P A P+
Sbjct: 236 QQLQRIAQLQ---LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQ 292
Query: 1004 KKVTKQENPP 1013
T+ PP
Sbjct: 293 MHHTQHHQPP 302
Score = 38.1 bits (87), Expect = 0.087
Identities = 43/161 (26%), Positives = 64/161 (39%), Gaps = 20/161 (12%)
Query: 617 RQAYTQKTTQLEHKSQMYQVEMN--QGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQ 674
+QA Q+ Q + + Q +Q + + Q Q Q V Q Q Q+ Q HL K H Q
Sbjct: 173 QQAALQQQQQ-QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQ-----QQHLIKLHHQ 226
Query: 675 SLCGTRFHFQQRADSQTEKLMSPV-LKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPS 733
+ QQ+ Q ++L L+ QQ + + LQ +P Q P
Sbjct: 227 N--------QQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP---PIQQPPM 275
Query: 734 QSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGS 774
Q P +Q Q+LQ + + Q P PQ Q + S
Sbjct: 276 QQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPS 316
Score = 35.4 bits (80), Expect = 0.56
Identities = 33/152 (21%), Positives = 57/152 (37%), Gaps = 13/152 (8%)
Query: 1465 RQRKLEAKKAAAEKLSSLENSSNKN-EKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQ 1523
+Q++L+ ++ + L L + + + ++++ R Q + Q +Q + Q
Sbjct: 206 QQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQ---------Q 256
Query: 1524 QSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSS 1583
Q QQ Q LQ QPP QQ P QQ P T + P P P +
Sbjct: 257 QQQQQQALQAQPPI---QQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN 313
Query: 1584 HTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPM 1615
S + + S + G L + P+
Sbjct: 314 QPSQLPPQSQTQPLVSQAQALPGQMLYTQPPL 345
Score = 33.5 bits (75), Expect = 2.1
Identities = 28/117 (23%), Positives = 53/117 (45%), Gaps = 7/117 (5%)
Query: 1465 RQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRT------KQTENASQAKQLAELLRLS 1518
+Q++ + ++ AA + + + + ++SA + +Q + Q +Q L++L
Sbjct: 165 QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLH 224
Query: 1519 GPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNP 1575
QQ QQ Q ++ Q Q QQ+ QQQQ Q + + P M++P P
Sbjct: 225 HQNQQQIQQQQQQLQRIAQLQLQQQ-QQQQQQQQQQQQQALQAQPPIQQPPMQQPQP 280
Score = 32.0 bits (71), Expect = 6.2
Identities = 17/42 (40%), Positives = 22/42 (52%)
Query: 1515 LRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTES 1556
L+L +QQ QQ Q Q+Q QQQ+ QQQQ +S
Sbjct: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQS 194
Score = 32.0 bits (71), Expect = 6.2
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 11/111 (9%)
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQH----KPHKQAAQTQPSQSSHL- 738
QQ+ Q ++ L+Q QQ + S + Q +Q Q Q Q HL
Sbjct: 162 QQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLI 221
Query: 739 ---PQNQQQ--QQKLQIKNKEEI-LQTFPHPQSNNDQQREGSFFGQTKVEE 783
QNQQQ QQ+ Q++ ++ LQ Q QQ++ + Q +++
Sbjct: 222 KLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
Score = 32.0 bits (71), Expect = 6.2
Identities = 38/186 (20%), Positives = 69/186 (37%), Gaps = 13/186 (6%)
Query: 725 KQAAQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEEC 784
+Q Q Q Q + L Q QQQQQ+ Q + ++ +Q QQ + Q + +
Sbjct: 164 QQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKL 223
Query: 785 FHGENQYSKSSEFETHNV-QMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSE 843
H Q + + + + Q+ L++ Q ++ Q + IQ
Sbjct: 224 HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ---------QPP 274
Query: 844 NKEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRN 903
++ P + Q +HH Q+ P+Q + Q Q + S Q ++
Sbjct: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQA 331
Query: 904 QDMSGQ 909
Q + GQ
Sbjct: 332 QALPGQ 337
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 45.1 bits (105), Expect = 7e-04
Identities = 138/630 (21%), Positives = 218/630 (34%), Gaps = 151/630 (23%)
Query: 396 TTPPPPS---QLLLSP---PPPLPQVP-QLPSEGKSTLNGGVLEEHHHYPNQSNTTLLRE 448
T PPP + + + P PPP +VP +LP E S EE H
Sbjct: 22 TVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQ-----EEKHM------------ 64
Query: 449 VKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPM 508
++G PE Q P E Q + + Q A L EKT+
Sbjct: 65 TAVKGLPEQECEQQQK--------EPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRD 116
Query: 509 SEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILK-----GRDKEQTRDLVPPTQHYLKPG 563
+ K +L++ + L + +QE++K G KEQ +L + +LK
Sbjct: 117 QQLNK----------QLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLK-- 164
Query: 564 WIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQK 623
HL++ E L Q + L LP Q Q
Sbjct: 165 --------------HLEQQEGQLKHPEQQEGQLE-----------------LPEQQEGQL 193
Query: 624 TTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHF 683
+ + Q+ E +GQ + Q Q + P Q LP+ L
Sbjct: 194 ELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ---EGQLELPQQQEGQL---ELSE 247
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQT-----QPSQSSHL 738
QQ + + LK HL Q + E P +Q Q Q Q HL
Sbjct: 248 QQEGQLELSEQQEGQLK-HLEHQEGQLEV----------PEEQMGQLKYLEQQEGQLKHL 296
Query: 739 PQNQQQ-----QQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVE-ECFHGENQYS 792
Q ++Q QQ Q+K+ E+ Q + +Q+EG + E + H E Q
Sbjct: 297 DQQEKQPELPEQQMGQLKHLEQ-----QEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEG 351
Query: 793 KSSEFETHNVQMGLEEVQNIN------RRNSPYSQTMKSSACKIQVSCSNNT-HLVSEN- 844
+ E Q+GL E Q + ++ P + K V HLV +
Sbjct: 352 QLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEG 411
Query: 845 -----KEQTTHPELFAGN------KTQNLHHMQYFPNNV-IPKQDLLHRCFQEQEQKSQQ 892
+ Q H E G + L H++ + +P+Q + EQE+K Q
Sbjct: 412 QLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEK--Q 469
Query: 893 ASVLQGYKNRNQDMSGQQAA-QLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAA 951
+ + + + + + Q+A +L +Q+ H +Q H + P Q+D Q
Sbjct: 470 LELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHL------EQQEKHLEHPEQQDGQ---- 519
Query: 952 LRWHLLQKQEQQQTQQPQTESCHSQMHRPI 981
L+ EQQ+ Q E Q+ +P+
Sbjct: 520 -----LKHLEQQEGQLKDLEQQKGQLEQPV 544
Score = 41.2 bits (95), Expect = 0.010
Identities = 91/455 (20%), Positives = 160/455 (35%), Gaps = 42/455 (9%)
Query: 570 PRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQA--YTQKTTQL 627
P + + +K+ P + L ++ SKQ + GLP Q QK Q
Sbjct: 25 PPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQE 84
Query: 628 EHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKT-DHLPKAHVQSLCGTRFHFQQR 686
+ Q + + + Q +Q L+ +K +K + K Q L ++
Sbjct: 85 QELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQ 144
Query: 687 ADSQTEKLMSPVLKQ-----HLNQQASETEPFSNSHLLQHKPHKQAAQTQ--PSQSSHLP 739
+ E+L+ +Q HL QQ + + P +Q Q + Q L
Sbjct: 145 LGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLE 204
Query: 740 QNQQQQQKLQIKNKEEILQTFPHPQSNN---DQQREGSFF------GQTKVEECFHGENQ 790
+QQ+ +L++ ++E P Q QQ+EG GQ ++ E G+ +
Sbjct: 205 LPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLK 264
Query: 791 YSKSSE--FETHNVQMG-LEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSENKEQ 847
+ + E E QMG L+ ++ + Q K Q HL + + Q
Sbjct: 265 HLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQ-QMGQLKHL-EQQEGQ 322
Query: 848 TTHPELFAGNKTQ----------------NLHHMQYFPNNV-IPKQDLLH-RCFQEQEQK 889
H E G Q L H+++ + +P+Q +L + ++Q+ +
Sbjct: 323 PKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQ 382
Query: 890 SQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKH 949
+ +G GQ + Q+ L V + Q G Q+ KH
Sbjct: 383 PKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKH 442
Query: 950 AALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVE 984
+ L+ EQQ Q E Q+ P + E
Sbjct: 443 LEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQE 477
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 44.3 bits (103), Expect = 0.001
Identities = 53/176 (30%), Positives = 71/176 (40%), Gaps = 26/176 (14%)
Query: 1526 QQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSSHT 1585
Q Q P QP Q Q QP+ Q S + YS S T+ Y + + S Y S +T
Sbjct: 9 QATQSYGAYPTQPGQGYSQQSSQPYGQQ--SYSGYSQSTDTSGYGQ--SSYSSYGQSQNT 64
Query: 1586 SDIYGSTS-PMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSVDNCSP 1644
YG+ S P + ST G Y +S + + Y Q + YP Y G + +
Sbjct: 65 G--YGTQSTPQGYGST-----GGYGSSQSSQSSY----GQQSSYPGY---GQQPAPSSTS 110
Query: 1645 YLGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPRFGNSQSFTSKYLGYGNQN 1700
GSY SQ Y P S+ P + Q +G QS+ GYG QN
Sbjct: 111 --GSYGSSSQSSS-YGQPQSGSYSQ---QPSYGGQQQSYGQQQSYNPPQ-GYGQQN 159
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 44.3 bits (103), Expect = 0.001
Identities = 23/95 (24%), Positives = 43/95 (45%)
Query: 1461 VKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGP 1520
+ T + +A + L + ++++ + +Q + Q +Q +
Sbjct: 2027 ISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQ 2086
Query: 1521 VMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTE 1555
+++Q QQ Q Q+Q Q QQQQ+ QQQQ H Q +
Sbjct: 2087 ILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQ 2121
Score = 42.7 bits (99), Expect = 0.004
Identities = 26/111 (23%), Positives = 51/111 (45%)
Query: 1452 RKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQL 1511
R +L E + +Q++ + ++ ++ + + ++++ R +Q + Q +Q
Sbjct: 2043 RSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQ 2102
Query: 1512 AELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSA 1562
+ + QQ QQ Q Q PPQPQ Q +PQ Q+ QT+ +A
Sbjct: 2103 QQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAA 2153
Score = 41.2 bits (95), Expect = 0.010
Identities = 54/220 (24%), Positives = 83/220 (37%), Gaps = 36/220 (16%)
Query: 552 LVPPTQHYLK--PGWIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNS 609
LV PT+H + G++ +AP + + +R LQ P +S MT G
Sbjct: 1984 LVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQT---LQQTPMIST-MTPMSAQGV- 2038
Query: 610 NMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLP 669
QA + T L + Q Q + Q Q Q Q Q Q+ Q H +
Sbjct: 2039 --------QAGVRSTAILPEQQQQQQQQQQQQQQQ----QQQQQQQQQQQYHIRQQQQQQ 2086
Query: 670 KAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQ 729
Q QQ+ Q ++ +Q QQ + + Q P + Q
Sbjct: 2087 ILRQQQ--------QQQQQQQQQQ------QQQQQQQQQQQQQHQQQQQQQAAPPQPQPQ 2132
Query: 730 TQPS-QSSHLPQNQQQQQKLQI--KNKEEILQTFPHPQSN 766
+QP Q L Q QQQQQ + + ++++ T P P +N
Sbjct: 2133 SQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTN 2172
Score = 40.0 bits (92), Expect = 0.023
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 4/92 (4%)
Query: 1477 EKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPP 1536
E+ + + ++++ + +Q + + +Q ++LR QQ QQ Q Q+Q
Sbjct: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
Query: 1537 QPQQQQ----RPQQQQPHHPQTESVNSYSASG 1564
Q QQQQ + QQ P PQ +S + G
Sbjct: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
Score = 40.0 bits (92), Expect = 0.023
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 1/90 (1%)
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQ 743
QQ+ Q ++ +Q QQ +L+ + +Q Q Q Q Q QQ
Sbjct: 2053 QQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ-QQQQQ 2111
Query: 744 QQQKLQIKNKEEILQTFPHPQSNNDQQREG 773
QQQ+ Q + +++ P PQS QR+G
Sbjct: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
Score = 38.1 bits (87), Expect = 0.087
Identities = 56/252 (22%), Positives = 95/252 (37%), Gaps = 18/252 (7%)
Query: 570 PRFHQAESHLKRNEASL--PSILQYQPNLSNQM-TSKQYTGNSNMPGGLPRQAYTQKTTQ 626
P+ + L++++ L S+ Q P+ S + TS+ YT + G
Sbjct: 1906 PQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVP 1965
Query: 627 LEHKSQMYQVEMNQGQSQGTVD--QHLQFQKPSHQVHFSKTDHLPKAHVQSLCGT-RFHF 683
+ SQ YQ + + VD +HLQ Q+PS VH + L T RF
Sbjct: 1966 PSYSSQPYQ-STHPSTNPTLVDPTRHLQ-QRPSGYVH-----QQAPTYGHGLTSTQRFSH 2018
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQN-- 741
Q + M+P+ Q + T Q + +Q Q Q Q Q
Sbjct: 2019 QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYH 2078
Query: 742 ---QQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFHGENQYSKSSEFE 798
QQQQQ L+ + +++ Q Q QQ++ Q + ++ + Q +F+
Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQ 2138
Query: 799 THNVQMGLEEVQ 810
+Q ++ Q
Sbjct: 2139 RQGLQQTQQQQQ 2150
Score = 36.6 bits (83), Expect = 0.25
Identities = 33/146 (22%), Positives = 55/146 (37%), Gaps = 27/146 (18%)
Query: 885 EQEQKSQQASVLQGYKNRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQK 944
EQ+Q+ QQ + + Q QQ Q QQ+Y I Q+
Sbjct: 2050 EQQQQQQQ-------QQQQQQQQQQQQQQQQQQQYHIR--------------------QQ 2082
Query: 945 DTQKHAALRWHLLQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWK 1004
Q+ + Q+Q+QQQ QQ Q + Q H+ + + P + P +
Sbjct: 2083 QQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGL 2142
Query: 1005 KVTKQENPPASCDNVQQKSIIETMEQ 1030
+ T+Q+ A+ Q+ + T Q
Sbjct: 2143 QQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Score = 36.2 bits (82), Expect = 0.33
Identities = 22/82 (26%), Positives = 35/82 (42%)
Query: 1492 EKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHH 1551
E+ + +Q + Q +Q + + + QQ QQ Q+Q Q QQQQ+ QQQQ
Sbjct: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
Query: 1552 PQTESVNSYSASGSTNPYMRRP 1573
Q + + P +P
Sbjct: 2110 QQQQQQHQQQQQQQAAPPQPQP 2131
Score = 33.9 bits (76), Expect = 1.6
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Query: 1493 KSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHH 1551
+ P + T ++Q Q P QQ QQ Q Q+Q Q QQQQ QQQQ +H
Sbjct: 2022 QQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQ--QQQQQYH 2078
Score = 32.0 bits (71), Expect = 6.2
Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 8/90 (8%)
Query: 1496 PSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQP---QQQQRPQQQQPHHP 1552
P + +Q + Q +Q + + QQ QQ +++Q Q QQQQ+ QQQQ
Sbjct: 2049 PEQQQQQQQQQQQQQQQQQQQ-----QQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQ 2103
Query: 1553 QTESVNSYSASGSTNPYMRRPNPVSPYPNS 1582
Q + ++ P P P S
Sbjct: 2104 QQQQQQQQQQQQHQQQQQQQAAPPQPQPQS 2133
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 44.3 bits (103), Expect = 0.001
Identities = 106/576 (18%), Positives = 212/576 (36%), Gaps = 67/576 (11%)
Query: 566 ELKAPRFH----QAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYT 621
E + R H Q H+ E L S + + + + S Q+ + +A
Sbjct: 898 EAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALK 957
Query: 622 QKTTQLEHKSQMYQVEMNQGQSQ--GTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGT 679
++ +L+ +++ E Q + + + K H+ + + L + ++L
Sbjct: 958 KQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAA- 1016
Query: 680 RFHFQQRADSQTEKLMSP------VLKQHLNQQASETEPFSNSH---LLQHKPHKQAAQT 730
++ AD++ +L + L H QA E E + SH LL+ + + A T
Sbjct: 1017 ----KEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALT 1072
Query: 731 ----QPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQREGSFFGQTKVEECFH 786
+ S+ L + Q+ + K + L+ + + +G G +
Sbjct: 1073 SQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALR 1132
Query: 787 GENQYSKSS--EFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSEN 844
N +++ + E VQ+ L+ VQ + +R + MK +Q S V+
Sbjct: 1133 EHNSILETALAKREADLVQLNLQ-VQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSL 1191
Query: 845 KEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKNRNQ 904
KEQ ++ AG H+ ++F + L +E + K LQ + Q
Sbjct: 1192 KEQVAAAKVEAG------HNRRHFKAASLE----LSEVKKELQAKEHLVQKLQAEADDLQ 1241
Query: 905 DMSGQQAAQLAQ-QRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHLLQKQEQQ 963
G+ + ++AQ Q L A + + Q P Q+ L+W + QK+ +
Sbjct: 1242 IREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQP-VGNQEMENLKWEVDQKEREI 1300
Query: 964 QTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASCDNVQQKS 1023
Q+ + Q + Q + ++ G + +N + + Q+
Sbjct: 1301 QSLKQQLDLTEQQGRKELE---GLQ------------------QLLQNVKSELEMAQEDL 1339
Query: 1024 IIETMEQHLKQFHAKSLFDHKALTLKSQKQVKVEMSGPVTVLTRQTTAAELDSHTPALEQ 1083
+ ++ + Q L ++ L+ +Q+K+++ TR+ E S PA
Sbjct: 1340 SMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRG-AAKTRKEPKGEASSSNPA--- 1395
Query: 1084 QTTSSEKTPTKRTAASVLNNFIESPSKLLDTPIKNL 1119
+ K P AS+L + P + P+KNL
Sbjct: 1396 ---TPIKIPDCPVPASLLEELLRPPPAVSKEPLKNL 1428
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 43.9 bits (102), Expect = 0.002
Identities = 124/546 (22%), Positives = 192/546 (35%), Gaps = 92/546 (16%)
Query: 399 PPPSQLLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAP 458
P + LL PP Q+P+ G++ PN+ N+ E +E +P
Sbjct: 1164 PSEASLLEGDPPFKSQIPKESGTGQAEAT----------PNEFNSQGSIEATME-RPLEK 1212
Query: 459 PSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCS---------EKTRPMS 509
PS S T S S+ P ++ N++ +++ PL S + T P +
Sbjct: 1213 PSCSLGIKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTSEQTTVPAT 1272
Query: 510 EHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKA 569
+L + +GS Q LM QE L + + LKP K
Sbjct: 1273 VNLTVSSSSYGS----QPPGPSLMTEYSQEQLNTMTSTIPNSQIQ--EPLLKPSHESRKD 1326
Query: 570 PRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEH 629
+ L + A Q P M+ T P + Q + +
Sbjct: 1327 SAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRT-----PDTISDQTQMMVSQIPPN 1381
Query: 630 KSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADS 689
S N G + PS+ T L + VQ CG++ ++ +
Sbjct: 1382 SSNSVVPVSNPAHGDGLT----RLFPPSNNF---VTPALRQTEVQ--CGSQPSVAEQQQT 1432
Query: 690 QTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQQQQKLQ 749
Q + + L+QH+ Q SHL H H Q Q Q Q QQQQQ Q
Sbjct: 1433 QASQHLQ-ALQQHVPAQGV-------SHL--HSNHLYIKQQQQQQQQQ-QQQQQQQQAGQ 1481
Query: 750 IKNKEEILQT---FPHPQS-------NNDQQR---------------EGSFFGQTKVEEC 784
++ + + Q PH +S N QQR +G+ Q ++
Sbjct: 1482 LRERHHLYQMQHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPK 1541
Query: 785 FHGENQ-YSKSSEFETHNVQMGLEEVQNINRRNSPYSQTMKSSACKIQVSCSNNTHLVSE 843
HG +Q SK+ + H+ QM + Q+ SQT KS C+ S S N H +
Sbjct: 1542 HHGTDQSRSKTGQPHPHHQQMQQQMQQHFGS-----SQTEKS--CE-NPSTSRNHHNHPQ 1593
Query: 844 N--KEQTTHPELFAGNKTQNLHHMQYFPNNVIPKQDLLHRCFQEQEQKSQQASVLQGYKN 901
N + H + G++ Q + P Q LL EQ+ SQ + V
Sbjct: 1594 NHLNQDIMHQQQDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQQMVSQPSIV-----T 1648
Query: 902 RNQDMS 907
R+ DM+
Sbjct: 1649 RSSDMT 1654
>gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
Length = 1962
Score = 43.9 bits (102), Expect = 0.002
Identities = 26/88 (29%), Positives = 40/88 (45%)
Query: 1462 KTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPV 1521
K +++K A+K A E+ + + + + T A+ A+ +
Sbjct: 35 KDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQ 94
Query: 1522 MQQSQQPQPLQKQPPQPQQQQRPQQQQP 1549
QQ QQ Q Q+Q PQ Q Q +PQQQQP
Sbjct: 95 PQQQQQQQQPQQQQPQQQPQPQPQQQQP 122
Score = 43.5 bits (101), Expect = 0.002
Identities = 56/214 (26%), Positives = 84/214 (39%), Gaps = 59/214 (27%)
Query: 1465 RQRKLEAKKAAAEKLSSLE------------NSSNKNEKEKSAPSRTKQ-TENASQAKQL 1511
++++ KKA +K+ E NS+N S + K+ T N Q +Q
Sbjct: 39 KKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQ 98
Query: 1512 AELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQ--PHHPQ---------------- 1553
+ QQ QQ QP Q+ PQPQQQQ QQ Q P +P+
Sbjct: 99 QQ--------QQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLK 150
Query: 1554 ---------------TESVNSYSASGS-TNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNF 1597
+ +NS S S + TN ++P NS + SDI STS ++
Sbjct: 151 RGQHFPVIAANLGSAVKVLNSQSESSALTN---QQPQNNGEVQNSKNQSDINHSTSGSHY 207
Query: 1598 YSTSSQAAGSYLNSS-NPMNPYPGLLNQNTQYPS 1630
++ S +SS N N L++ +PS
Sbjct: 208 ENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPS 241
Score = 41.2 bits (95), Expect = 0.010
Identities = 36/137 (26%), Positives = 49/137 (35%), Gaps = 25/137 (18%)
Query: 1467 RKLEAK--KAAAEKLS-SLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQ 1523
R+LEAK K LS L + +EK K+ + A+Q K + +++ +
Sbjct: 2 RELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKP 61
Query: 1524 QSQQPQPLQ----------------------KQPPQPQQQQRPQQQQPHHPQTESVNSYS 1561
QPQP +QP Q QQQQ+PQQQQP
Sbjct: 62 SVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQ 121
Query: 1562 ASGSTNPYMRRPNPVSP 1578
R P V P
Sbjct: 122 PQQQPQALPRYPREVPP 138
Score = 35.8 bits (81), Expect = 0.43
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 5/93 (5%)
Query: 1490 EKEKSAPSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQP 1549
+++++ R+ + N Q Q L + +MQQS+Q P +QQ P QQQP
Sbjct: 1422 QQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLV----KQQTPPSQQQP 1477
Query: 1550 -HHPQTESVNSYSASGSTNPYMRRPNPVSPYPN 1581
H P +S +T + P+P++ + N
Sbjct: 1478 LHQPAMKSFLDNVMPHTTPELQKGPSPINAFSN 1510
Score = 35.0 bits (79), Expect = 0.74
Identities = 46/209 (22%), Positives = 76/209 (36%), Gaps = 21/209 (10%)
Query: 533 MRNKEQEILKGRDKEQTRDLVPPTQHYL------KPGWIELKAPRFHQAESHLKRNEASL 586
MR E + K ++ +RDLV + + K + +A + E +K E
Sbjct: 1 MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIK 60
Query: 587 PSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLEHKSQMYQVEMNQGQSQGT 646
PS+ Q QP SN TS + N+N R + Q + + Q Q + Q Q Q
Sbjct: 61 PSVSQPQPANSNNGTSTATSTNNN----AKRATANNQQPQQQQQQQQPQQQQPQQQPQPQ 116
Query: 647 VDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHFQQRADSQTEKLMSPVLKQHLNQQ 706
Q Q+P + + +P RF Q+ PV+ +L
Sbjct: 117 PQQQQPQQQPQALPRYPR--EVP---------PRFRHQEHKQLLKRGQHFPVIAANLGSA 165
Query: 707 ASETEPFSNSHLLQHKPHKQAAQTQPSQS 735
S S L ++ + + Q S++
Sbjct: 166 VKVLNSQSESSALTNQQPQNNGEVQNSKN 194
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 43.9 bits (102), Expect = 0.002
Identities = 57/239 (23%), Positives = 86/239 (35%), Gaps = 48/239 (20%)
Query: 1401 EDNREFGGKPEDEQLH---VLPLYKVSDVDEFG---------------SVEAQEEKKRSG 1442
ED E+ +PE+EQL+ VL + +DEF S E +E+ + SG
Sbjct: 157 EDQIEYVEEPEEEQLYTDEVLDIEINEPLDEFTGGMETLELQKDIKEESDEEEEDDEESG 216
Query: 1443 AIQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSA------- 1495
++ + + + V R+ E + +AE ++L + + K
Sbjct: 217 RLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSRRG 276
Query: 1496 -------------PSRTKQTENASQAKQLAELLRLSGPVMQQS--QQPQPLQKQP----- 1535
R + TE LL PV+ Q+ P P Q+QP
Sbjct: 277 GRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLF 336
Query: 1536 -PQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSP-YPNSSHTSDIYGST 1592
PQP Q P Q PHHP T M P PV+P P + H + + T
Sbjct: 337 QPQPLQPLLP-VQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGT 394
Score = 38.5 bits (88), Expect = 0.067
Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 1517 LSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHP 1552
L GP+ P P Q QP QPQQQ PQ Q PH P
Sbjct: 578 LQGPL--HPPLPPPHQPQPQQPQQQPPPQHQPPHQP 611
Score = 36.2 bits (82), Expect = 0.33
Identities = 39/168 (23%), Positives = 63/168 (37%), Gaps = 8/168 (4%)
Query: 1520 PVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPY 1579
P Q QP P + PPQ Q PQ Q HH SV + P RP+ +
Sbjct: 607 PPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQF-RPHVQTAQ 665
Query: 1580 PNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNSSNPMNPYPGLLNQNTQYPSYQCNGNLSV 1639
P +S + + +TS + + P P L + PS+ + S
Sbjct: 666 PQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSR 725
Query: 1640 DNCSPY-----LGSYSPQSQPMDLYRYPSQDPLSKLSLPPIHTLYQPR 1682
+ +P + S SP S+ + R S +++ + P + QP+
Sbjct: 726 CSATPSAQVKPIVSASPPSRAVAGSR--SSQGKTEVKVKPASPVAQPK 771
Score = 33.9 bits (76), Expect = 1.6
Identities = 18/39 (46%), Positives = 18/39 (46%), Gaps = 6/39 (15%)
Query: 1520 PVMQQSQQPQPLQKQPPQ------PQQQQRPQQQQPHHP 1552
P QQ QQ P Q QPP P Q Q P Q P HP
Sbjct: 592 PQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHP 630
Score = 31.6 bits (70), Expect = 8.2
Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 1520 PVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHP 1552
P + QPQP Q Q QP Q +P Q PH P
Sbjct: 584 PPLPPPHQPQPQQPQ-QQPPPQHQPPHQPPHQP 615
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 43.1 bits (100), Expect = 0.003
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 36/177 (20%)
Query: 1461 VKTCRQRKLEAKKAAAEKLSSLE---NSSNKNEKEKSAPSRTKQTENASQAKQLAELLRL 1517
+ T + L+A + +L L+ + ++++ PS + + A QA ++
Sbjct: 161 IMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQ---- 216
Query: 1518 SGPVMQQSQQPQPLQKQPP----------QPQQQQRPQQQQPH-HPQ-------TESVNS 1559
QQ QP P Q+ PP Q QQ +PQQ QPH H Q T+ +S
Sbjct: 217 -----QQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSS 271
Query: 1560 YSASGSTNPYMRRPNPVSP-----YPNSSHTSDIYGSTSPMNFYSTSSQAAGSYLNS 1611
S +P P+P++P N+ S + + M+ + SSQA G+ L+S
Sbjct: 272 PPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIA-SSQAFGNALSS 327
Score = 34.3 bits (77), Expect = 1.3
Identities = 43/176 (24%), Positives = 61/176 (34%), Gaps = 18/176 (10%)
Query: 316 FQKPEQLQQQKSVFEICPSPAENNIQGTTKLASGEEFCSGSSSNLQAPGGSSERYLKQNE 375
F QL Q+ + P+ NIQG A+ + NLQA + + +
Sbjct: 125 FNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQL 184
Query: 376 MNGAYFKQSSVFTKDSFSATTTPPP--PSQLLLSP--------PPPLPQVPQLP-SEGKS 424
+Q S + P P PSQ P PPP Q P P S+ +
Sbjct: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQ 244
Query: 425 TLNGGVLEEHHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERP 480
+ H H NQ+ + ++ P PSQSP PSP+ P
Sbjct: 245 APQPQQHQPHSHSQNQNQPSPTQQ---SSSPPQKPSQSPGHGL----PSPLTPPNP 293
Score = 34.3 bits (77), Expect = 1.3
Identities = 35/143 (24%), Positives = 54/143 (37%), Gaps = 13/143 (9%)
Query: 901 NRNQDMSGQQAAQLAQQRYLIHNHANVFPVPDQGGSHTQTPPQKDTQKHAALRWHL---- 956
N + GQQ L + N + GG T P ++ Q ++L L
Sbjct: 126 NMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGG--IMTLPLQNLQATSSLNSQLQQLQ 183
Query: 957 LQKQEQQQTQQPQTESCHSQMHRPIKVEPGCKPHACMHTAPPENKTWKKVTKQENPPASC 1016
LQ Q+QQQ QQ Q +Q +P P + PP+ + + PPA
Sbjct: 184 LQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQ----QPPPASQQPPAPT 239
Query: 1017 DNVQQKSIIETMEQHLKQFHAKS 1039
+QQ +QH H+++
Sbjct: 240 SQLQQ---APQPQQHQPHSHSQN 259
>gi|116805330 small conductance calcium-activated potassium channel
protein 3 isoform a [Homo sapiens]
Length = 731
Score = 42.7 bits (99), Expect = 0.004
Identities = 49/195 (25%), Positives = 73/195 (37%), Gaps = 25/195 (12%)
Query: 1496 PSRTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQ----PQQQQRPQQQQPHH 1551
PS + + Q +Q + + P Q LQ QPPQ QQQQ+ QQQQP H
Sbjct: 24 PSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPH 83
Query: 1552 P-----QTESVNSYSASGSTNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNFY-------- 1598
P Q +S + ++P R P S H S GS +N +
Sbjct: 84 PLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSS 143
Query: 1599 -STSSQAAGSYLNSSNPM------NPYPGLLNQNTQYPSYQCNGNLSVDNCSPYLGSYSP 1651
+TS GS ++P+ NP+ + + +Y + L
Sbjct: 144 TATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAET 203
Query: 1652 QSQPMDLYRYPSQDP 1666
+ QP+ L+ PS P
Sbjct: 204 EGQPLQLFS-PSNPP 217
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 42.7 bits (99), Expect = 0.004
Identities = 48/194 (24%), Positives = 78/194 (40%), Gaps = 26/194 (13%)
Query: 1402 DNREFGGKPEDEQLHVL----PLYKVSDVDEFGSVEAQEEKKRSGAIQ-----VLSSFRR 1452
D + G+ +H++ P K S+ DE +E E + ++ V S R+
Sbjct: 621 DINKLPGEKLGRVVHIIQSREPSLKNSNPDE---IEIDFETLKPSTLRELERYVTSCLRK 677
Query: 1453 KVRMLAEPVKTCRQRKLEAKKAAAEKLSSLENSSNKNE----------KEKSAPSRTKQT 1502
K + AE V +++E SS E+SS+ +E K+K P R ++
Sbjct: 678 KRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKK 737
Query: 1503 ENASQAKQLAELLRLSGPVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSA 1562
+ +Q+ + PV QQ P PP PQQQQ+P P P + +
Sbjct: 738 HHHHHHQQMQQA---PAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPP-PPSMPQQAAPAM 793
Query: 1563 SGSTNPYMRRPNPV 1576
S P++ PV
Sbjct: 794 KSSPPPFIATQVPV 807
Score = 38.5 bits (88), Expect = 0.067
Identities = 89/410 (21%), Positives = 145/410 (35%), Gaps = 77/410 (18%)
Query: 398 PPPP-----SQLLLSPPPPLPQVPQLPSEGKSTLNGGVLEEHHHYPNQSNTTLLREVKIE 452
PPPP QL PPPP P PQ P + + + H P Q +T + + +
Sbjct: 959 PPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQ---HQPPPRPVHLQPMQFSTHIQQPPPPQ 1015
Query: 453 GK--PEAPPSQSPNPSTHVCSPSPMLSERPQNNCVNRNDIQTAGTMTVPLCSEKTRPMSE 510
G+ P PP Q P P P P +PQ + +
Sbjct: 1016 GQQPPHPPPGQQPPP------PQP---AKPQQVIQHHHS-------------------PR 1047
Query: 511 HLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPGWIELKAP 570
H K +P S+G L++ LM + Q + Q+ P Q ++P EL+A
Sbjct: 1048 HHKSDP---YSTGHLREAPSPLMIHSPQ-----MSQFQSLTHQSPPQQNVQPKKQELRAA 1099
Query: 571 RFHQAESHLKRNEASLPS-ILQYQP-NLSNQMTSKQYTGNSNMPGGLPRQAYTQKTTQLE 628
Q + + E + S I++ +P + S + ++ + P LP++ + ++
Sbjct: 1100 SVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQR---PEMKPVD 1156
Query: 629 HKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQV---------HFSKTDHLPKAHVQSLCGT 679
+ + G D+ Q Q+P V + L + H + T
Sbjct: 1157 VGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSST 1216
Query: 680 ---------RFHFQQRADSQTEKLMSPVL------KQHLNQQASETEPFSNSHLLQHKPH 724
+F R + EK + K+ L Q+ + ++ + H
Sbjct: 1217 AKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAH 1276
Query: 725 KQA--AQTQPSQSSHLPQNQQQQQKLQIKNKEEILQTFPHPQSNNDQQRE 772
++A Q Q Q Q QQQQQ + PQS DQQRE
Sbjct: 1277 EEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRE 1326
Score = 36.2 bits (82), Expect = 0.33
Identities = 32/116 (27%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Query: 1460 PVKTCRQRKLEAKKAAAEKLSSLENSSNKNEKEKSAPSRTKQTENASQAKQLAELLRLSG 1519
P+ Q LE ++ A L+S++ + +K P Q++ L
Sbjct: 904 PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH 963
Query: 1520 PVMQQSQQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNP 1575
P +QQ Q QP PPQPQ P QQ H P V+ ST ++++P P
Sbjct: 964 PSVQQQLQQQPPPPPPPQPQ----PPPQQQHQPPPRPVHLQPMQFST--HIQQPPP 1013
Score = 33.5 bits (75), Expect = 2.1
Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 5/80 (6%)
Query: 1520 PVMQQSQQPQPLQKQPPQPQQQQRPQQ--QQPHHPQTESVNSYSAS---GSTNPYMRRPN 1574
P Q Q P P Q P P Q +PQQ Q H P+ + YS + +P M
Sbjct: 1012 PPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSP 1071
Query: 1575 PVSPYPNSSHTSDIYGSTSP 1594
+S + + +H S + P
Sbjct: 1072 QMSQFQSLTHQSPPQQNVQP 1091
Score = 32.7 bits (73), Expect = 3.7
Identities = 72/372 (19%), Positives = 121/372 (32%), Gaps = 50/372 (13%)
Query: 392 FSATTTPPPPSQLLLSPPPPLPQVPQLPSEGKSTLNGGVLEEH----HHYPNQSNTTLLR 447
FS PPP Q P PP Q P P K V++ H HH + +T LR
Sbjct: 1004 FSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQ---QVIQHHHSPRHHKSDPYSTGHLR 1060
Query: 448 EVKIEGKPEAPPSQSPNPSTHVCSPSPMLSERPQN----NCVNRNDIQTAGTMTVPLCSE 503
E +P TH P + + Q + V + +
Sbjct: 1061 EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPII 1120
Query: 504 KTRPMSEHLKHNPPIFGSSGELQDNCQQLMRNKEQEILKGRDKEQTRDLVPPTQHYLKPG 563
++ P S L+ PP S + + Q K ++ + + ++ PP
Sbjct: 1121 RSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQ 1180
Query: 564 WIELKAPRFHQAESHLKRNEASLPSILQYQPNLSNQMTSKQYTGNSNMPGGLPRQAYTQK 623
E K P + + +K N S S++Q P T+ T S+ ++ Q
Sbjct: 1181 KQEPKTPVAPKKDLKIK-NMGSWASLVQKHP------TTPSSTAKSS------SDSFEQF 1227
Query: 624 TTQLEHKSQMYQVEMNQGQSQGTVDQHLQFQKPSHQVHFSKTDHLPKAHVQSLCGTRFHF 683
K + + Q + + L+ ++ + + +AH ++
Sbjct: 1228 RRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQ 1287
Query: 684 QQRADSQTEKLMSPVLKQHLNQQASETEPFSNSHLLQHKPHKQAAQTQPSQSSHLPQNQQ 743
QQR + Q Q QQA+ AA P S PQ+
Sbjct: 1288 QQRQEQQ----------QQQQQQAAAV----------------AAAATPQAQSSQPQSML 1321
Query: 744 QQQKLQIKNKEE 755
QQ+ + +E+
Sbjct: 1322 DQQRELARKREQ 1333
Score = 32.0 bits (71), Expect = 6.2
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 2/75 (2%)
Query: 409 PPPLPQVPQLPSEGKSTLNGGVLEE--HHHYPNQSNTTLLREVKIEGKPEAPPSQSPNPS 466
PP LPQ P+ + + V H+ P Q + R + KP PP+ SP +
Sbjct: 836 PPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALT 895
Query: 467 THVCSPSPMLSERPQ 481
P P +++ PQ
Sbjct: 896 QTPLLPQPPMAQPPQ 910
Score = 31.6 bits (70), Expect = 8.2
Identities = 24/89 (26%), Positives = 35/89 (39%), Gaps = 13/89 (14%)
Query: 1526 QQPQPLQKQPPQPQQQQRPQQQQPHHPQTESVNSYSASGSTNPYMRRPNPVSPYPNSSHT 1585
Q P P +QPP P Q+P QP PQ + +S P + +P S T
Sbjct: 1010 QPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHS------PRHHKSDPYS-------T 1056
Query: 1586 SDIYGSTSPMNFYSTSSQAAGSYLNSSNP 1614
+ + SP+ +S S + S P
Sbjct: 1057 GHLREAPSPLMIHSPQMSQFQSLTHQSPP 1085
>gi|116235460 YTH domain family, member 3 [Homo sapiens]
Length = 585
Score = 42.7 bits (99), Expect = 0.004
Identities = 34/97 (35%), Positives = 43/97 (44%), Gaps = 19/97 (19%)
Query: 1520 PVMQQSQQPQPLQKQPPQPQQQQRPQ-QQQPHHPQTE----------------SVNSYSA 1562
P + QSQ PQ Q QPPQPQQQQ PQ Q QPH Q + N +
Sbjct: 311 PPLVQSQLPQQ-QPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNNG 369
Query: 1563 SGSTNPYMRRPNPVSPYPNSSHTSDIYGSTSPMNFYS 1599
+GS N + PVS P+S + +N Y+
Sbjct: 370 AGSEN-FGLGVVPVSASPSSVEVHPVLEKLKAINNYN 405
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,398,990
Number of Sequences: 37866
Number of extensions: 4516476
Number of successful extensions: 27846
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 446
Number of HSP's that attempted gapping in prelim test: 19057
Number of HSP's gapped (non-prelim): 5796
length of query: 2002
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1885
effective length of database: 13,817,196
effective search space: 26045414460
effective search space used: 26045414460
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.