Guide to the Human Genome
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Search of human proteins with 18765709

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1
[Homo sapiens]
         (448 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho...   929   0.0  
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H...   782   0.0  
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho...   782   0.0  
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas...   387   e-107
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs...   179   6e-45
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso...   151   1e-36
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso...   151   1e-36
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                  133   3e-31
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                  133   3e-31
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                  133   3e-31
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                  133   3e-31
gi|26190608 synaptojanin 2 [Homo sapiens]                             129   7e-30
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...   119   4e-27
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ...   110   3e-24
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ...   110   3e-24
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]      93   6e-19
gi|119943086 Tax1 (human T-cell leukemia virus type I) binding p...    42   0.001
gi|21361682 Tax1 (human T-cell leukemia virus type I) binding pr...    42   0.001
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]     40   0.003
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H...    37   0.028
gi|109702906 inositol polyphosphate-5-phosphatase A [Homo sapiens]     32   1.5  
gi|66392146 RNA U, small nuclear RNA export adaptor (phosphoryla...    30   4.4  
gi|62241001 conserved helix-loop-helix ubiquitous kinase [Homo s...    29   7.6  
gi|27477111 step II splicing factor SLU7 [Homo sapiens]                29   7.6  
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ...    29   9.9  
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ...    29   9.9  
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [...    29   9.9  

>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
           sapiens]
          Length = 448

 Score =  929 bits (2401), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 1   MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELNSGII 60
           MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELNSGII
Sbjct: 1   MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELNSGII 60

Query: 61  SLLSDAAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPT 120
           SLLSDAAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPT
Sbjct: 61  SLLSDAAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPT 120

Query: 121 GLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPN 180
           GLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPN
Sbjct: 121 GLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPN 180

Query: 181 ILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGR 240
           ILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGR
Sbjct: 181 ILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGR 240

Query: 241 LLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGY 300
           LLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGY
Sbjct: 241 LLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGY 300

Query: 301 SSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPW 360
           SSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPW
Sbjct: 301 SSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPW 360

Query: 361 DWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLR 420
           DWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLR
Sbjct: 361 DWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLR 420

Query: 421 SVVGISRPFQIPPGSLREDPLGEAQPQI 448
           SVVGISRPFQIPPGSLREDPLGEAQPQI
Sbjct: 421 SVVGISRPFQIPPGSLREDPLGEAQPQI 448


>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
           sapiens]
          Length = 372

 Score =  782 bits (2020), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 77  MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 136
           MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL
Sbjct: 1   MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60

Query: 137 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 196
           KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR
Sbjct: 61  KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120

Query: 197 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 256
           IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY
Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180

Query: 257 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 316
           DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG
Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240

Query: 317 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 376
           TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY
Sbjct: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300

Query: 377 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 436
           VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL
Sbjct: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360

Query: 437 REDPLGEAQPQI 448
           REDPLGEAQPQI
Sbjct: 361 REDPLGEAQPQI 372


>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
           sapiens]
          Length = 372

 Score =  782 bits (2020), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 77  MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 136
           MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL
Sbjct: 1   MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICL 60

Query: 137 KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 196
           KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR
Sbjct: 61  KLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFR 120

Query: 197 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 256
           IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY
Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180

Query: 257 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 316
           DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG
Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240

Query: 317 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 376
           TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY
Sbjct: 241 TFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDY 300

Query: 377 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 436
           VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL
Sbjct: 301 VSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSL 360

Query: 437 REDPLGEAQPQI 448
           REDPLGEAQPQI
Sbjct: 361 REDPLGEAQPQI 372


>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase,
           A [Homo sapiens]
          Length = 638

 Score =  387 bits (993), Expect = e-107
 Identities = 198/426 (46%), Positives = 262/426 (61%), Gaps = 7/426 (1%)

Query: 8   GPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRNLN--LDIYVIGLQELNSGIISLLSD 65
           GP   R++  VVTWNV +A PP D++ LL L   + +   D+  IGLQE+NS +   L D
Sbjct: 51  GPSEPRIT--VVTWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLKD 108

Query: 66  AAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGY 125
           A F D WS   MD L P +F+ VS VRMQG++LL+FAKY HLP+++ + T  T TGL GY
Sbjct: 109 ALFTDQWSELFMDALGPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGY 168

Query: 126 WGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHD 185
           WGNKGGV++ L  +G+ +  +NCHLP H+    QR ++F  IL +Q  +G     ILDHD
Sbjct: 169 WGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQGILDHD 228

Query: 186 LIIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPP 245
           L+ WFGD+NFRIE + LHFV+ +I +     LWEKDQL++AK   P+L+ FQEG L F P
Sbjct: 229 LVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAP 288

Query: 246 TYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMT 305
           T+KFD  +N YDTS KKRKPAWTDRILW++K  P  GP      +    ++   Y SHM 
Sbjct: 289 TFKFDVGTNKYDTSAKKRKPAWTDRILWKVK-APGGGPSPSGRKSHRLQVTQHSYRSHME 347

Query: 306 YGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGL 365
           Y +SDHKPV+  F L+       PL+ L   D W      +V Y   + F  S WDWIGL
Sbjct: 348 YTVSDHKPVAAQFLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGL 407

Query: 366 YKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGI 425
           Y+VG R   DYV+Y W     V    N  QV     ++P    +F+L YYS++   ++GI
Sbjct: 408 YRVGFRHCKDYVAYVWAKHEDV--DGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGI 465

Query: 426 SRPFQI 431
           + PFQI
Sbjct: 466 TEPFQI 471


>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
           [Homo sapiens]
          Length = 913

 Score =  179 bits (453), Expect = 6e-45
 Identities = 109/310 (35%), Positives = 163/310 (52%), Gaps = 25/310 (8%)

Query: 20  TWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELN-SGIISLLSDAAFNDSWSSFLMD 78
           T+NV   +P   L   L L+N     D+Y +G QEL+ S       D    + W   + +
Sbjct: 271 TYNVNGQSPKECLR--LWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSE 328

Query: 79  VLSP-LSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLK 137
            L P   + KV  +R+ GI+LL++ K +H  YI  +  ++  TG+ G  GNKGGV I  +
Sbjct: 329 GLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQ 388

Query: 138 LYGYYVSIINCHLPPHISNNYQRLEHFDRILE-MQNCE-GRDIP--NILDHDLIIWFGDM 193
            +   + ++N HL  HI    +R + +  I   MQ C+    +P   I +HD+I+W GD+
Sbjct: 389 FHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDL 448

Query: 194 NFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNS 253
           N+RIE+  +  V++ I+ + +  L+  DQL I      +   F EG L F PTYK+D  S
Sbjct: 449 NYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGS 508

Query: 254 NDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKP 313
           +D+DTSEK R PAW DRILW+ K                 +++   Y SHM    SDHKP
Sbjct: 509 DDWDTSEKCRAPAWCDRILWKGK-----------------NITQLSYQSHMALKTSDHKP 551

Query: 314 VSGTFDLELK 323
           VS  FD+ ++
Sbjct: 552 VSSVFDIGVR 561


>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
           isoform b [Homo sapiens]
          Length = 893

 Score =  151 bits (381), Expect = 1e-36
 Identities = 100/312 (32%), Positives = 155/312 (49%), Gaps = 25/312 (8%)

Query: 18  VVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELNSGIISLLS-DAAFNDSWSSFL 76
           V TWNV   +P   L   L  +      DIY IG QEL+    +    ++     WS  +
Sbjct: 244 VGTWNVNGQSPDSGLEPWLNCDPNPP--DIYCIGFQELDLSTEAFFYFESVKEQEWSMAV 301

Query: 77  MDVL-SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNIC 135
              L S   + KV  VR+ G++LL+FA+     YI+ ++T++  TG+ G  GNKGGV + 
Sbjct: 302 ERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVR 361

Query: 136 LKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFG 191
              +     I+N HL  H+ +  +R + +  I    +     + +P  NI+ H+++IW G
Sbjct: 362 FVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLG 421

Query: 192 DMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDR 251
           D+N+R+     + V+  I  +    L + DQL+I +       +F EG + F PTYK+D 
Sbjct: 422 DLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDS 481

Query: 252 NSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDH 311
            ++ +D+S K R PAW DRILWR                   +++   Y SHM    SDH
Sbjct: 482 KTDRWDSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDH 524

Query: 312 KPVSGTFDLELK 323
           KPVS  F + +K
Sbjct: 525 KPVSALFHIGVK 536


>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
           isoform a [Homo sapiens]
          Length = 901

 Score =  151 bits (381), Expect = 1e-36
 Identities = 100/312 (32%), Positives = 155/312 (49%), Gaps = 25/312 (8%)

Query: 18  VVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELNSGIISLLS-DAAFNDSWSSFL 76
           V TWNV   +P   L   L  +      DIY IG QEL+    +    ++     WS  +
Sbjct: 244 VGTWNVNGQSPDSGLEPWLNCDPNPP--DIYCIGFQELDLSTEAFFYFESVKEQEWSMAV 301

Query: 77  MDVL-SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNIC 135
              L S   + KV  VR+ G++LL+FA+     YI+ ++T++  TG+ G  GNKGGV + 
Sbjct: 302 ERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVR 361

Query: 136 LKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFG 191
              +     I+N HL  H+ +  +R + +  I    +     + +P  NI+ H+++IW G
Sbjct: 362 FVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLG 421

Query: 192 DMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDR 251
           D+N+R+     + V+  I  +    L + DQL+I +       +F EG + F PTYK+D 
Sbjct: 422 DLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDS 481

Query: 252 NSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDH 311
            ++ +D+S K R PAW DRILWR                   +++   Y SHM    SDH
Sbjct: 482 KTDRWDSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDH 524

Query: 312 KPVSGTFDLELK 323
           KPVS  F + +K
Sbjct: 525 KPVSALFHIGVK 536


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score =  133 bits (335), Expect = 3e-31
 Identities = 98/301 (32%), Positives = 153/301 (50%), Gaps = 23/301 (7%)

Query: 39  NNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDS-WSSFLMDVLS-PLSFIKVSHVRM 93
           + R+   DI+ IG +E   LN+G  +++S +  N   W+  L   +S    ++ ++  ++
Sbjct: 576 DKRSKPTDIFAIGFEEMVELNAG--NIVSASTTNQKLWAVELQKTISRDNKYVLLASEQL 633

Query: 94  QGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPH 153
            G+ L VF + QH P+I+ ++  +  TG+ G  GNKG V I +  +   +  +  H    
Sbjct: 634 VGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAG 693

Query: 154 ISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNR 212
            S   +R E F  I    +   GR    +  HD + W GD N+RI D     V+E I+ +
Sbjct: 694 QSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNEEVKELIRQQ 749

Query: 213 CYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRIL 272
            +  L   DQL   K    + R F EG++ F PTYK+D  S+DYDTSEK R PAWTDR+L
Sbjct: 750 NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVL 809

Query: 273 WRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHKPVSGTFDLE 321
           WR ++ P   +  D  +  AS    S   Y+    + + YG      SDH+PV    D++
Sbjct: 810 WRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDID 869

Query: 322 L 322
           +
Sbjct: 870 I 870


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score =  133 bits (335), Expect = 3e-31
 Identities = 98/301 (32%), Positives = 153/301 (50%), Gaps = 23/301 (7%)

Query: 39  NNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDS-WSSFLMDVLS-PLSFIKVSHVRM 93
           + R+   DI+ IG +E   LN+G  +++S +  N   W+  L   +S    ++ ++  ++
Sbjct: 615 DKRSKPTDIFAIGFEEMVELNAG--NIVSASTTNQKLWAVELQKTISRDNKYVLLASEQL 672

Query: 94  QGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPH 153
            G+ L VF + QH P+I+ ++  +  TG+ G  GNKG V I +  +   +  +  H    
Sbjct: 673 VGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAG 732

Query: 154 ISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNR 212
            S   +R E F  I    +   GR    +  HD + W GD N+RI D     V+E I+ +
Sbjct: 733 QSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNEEVKELIRQQ 788

Query: 213 CYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRIL 272
            +  L   DQL   K    + R F EG++ F PTYK+D  S+DYDTSEK R PAWTDR+L
Sbjct: 789 NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVL 848

Query: 273 WRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHKPVSGTFDLE 321
           WR ++ P   +  D  +  AS    S   Y+    + + YG      SDH+PV    D++
Sbjct: 849 WRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDID 908

Query: 322 L 322
           +
Sbjct: 909 I 909


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score =  133 bits (335), Expect = 3e-31
 Identities = 98/301 (32%), Positives = 153/301 (50%), Gaps = 23/301 (7%)

Query: 39  NNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDS-WSSFLMDVLS-PLSFIKVSHVRM 93
           + R+   DI+ IG +E   LN+G  +++S +  N   W+  L   +S    ++ ++  ++
Sbjct: 615 DKRSKPTDIFAIGFEEMVELNAG--NIVSASTTNQKLWAVELQKTISRDNKYVLLASEQL 672

Query: 94  QGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPH 153
            G+ L VF + QH P+I+ ++  +  TG+ G  GNKG V I +  +   +  +  H    
Sbjct: 673 VGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAG 732

Query: 154 ISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNR 212
            S   +R E F  I    +   GR    +  HD + W GD N+RI D     V+E I+ +
Sbjct: 733 QSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNEEVKELIRQQ 788

Query: 213 CYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRIL 272
            +  L   DQL   K    + R F EG++ F PTYK+D  S+DYDTSEK R PAWTDR+L
Sbjct: 789 NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVL 848

Query: 273 WRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHKPVSGTFDLE 321
           WR ++ P   +  D  +  AS    S   Y+    + + YG      SDH+PV    D++
Sbjct: 849 WRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDID 908

Query: 322 L 322
           +
Sbjct: 909 I 909


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score =  133 bits (335), Expect = 3e-31
 Identities = 98/301 (32%), Positives = 153/301 (50%), Gaps = 23/301 (7%)

Query: 39  NNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDS-WSSFLMDVLS-PLSFIKVSHVRM 93
           + R+   DI+ IG +E   LN+G  +++S +  N   W+  L   +S    ++ ++  ++
Sbjct: 571 DKRSKPTDIFAIGFEEMVELNAG--NIVSASTTNQKLWAVELQKTISRDNKYVLLASEQL 628

Query: 94  QGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPH 153
            G+ L VF + QH P+I+ ++  +  TG+ G  GNKG V I +  +   +  +  H    
Sbjct: 629 VGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAG 688

Query: 154 ISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNR 212
            S   +R E F  I    +   GR    +  HD + W GD N+RI D     V+E I+ +
Sbjct: 689 QSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNEEVKELIRQQ 744

Query: 213 CYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRIL 272
            +  L   DQL   K    + R F EG++ F PTYK+D  S+DYDTSEK R PAWTDR+L
Sbjct: 745 NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVL 804

Query: 273 WRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHKPVSGTFDLE 321
           WR ++ P   +  D  +  AS    S   Y+    + + YG      SDH+PV    D++
Sbjct: 805 WRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDID 864

Query: 322 L 322
           +
Sbjct: 865 I 865


>gi|26190608 synaptojanin 2 [Homo sapiens]
          Length = 1496

 Score =  129 bits (323), Expect = 7e-30
 Identities = 102/357 (28%), Positives = 165/357 (46%), Gaps = 40/357 (11%)

Query: 1   MSSRKLSGPKGRRLSIHVVTWNV-------ASAAPPLDLSDLLQLNNRNLN--------- 44
           M+ R+      +R+ I + TWNV       ++     +L+D L L++  L+         
Sbjct: 517 MTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTAELTDWL-LDSPQLSGATDSQDDS 575

Query: 45  --LDIYVIGLQELNSGIISLLSDAAFNDS--WSSFLMDVLSPLS-FIKVSHVRMQGILLL 99
              DI+ +G +E+       + +A+  +   W   L   +S    +I ++  ++ G+ L 
Sbjct: 576 SPADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCLY 635

Query: 100 VFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQ 159
           +F +  H+P+I+ ++  +  TG+ G  GNKG V I  + +      I  HL    S   +
Sbjct: 636 IFVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKE 695

Query: 160 RLEHFDRILEMQNC--EGRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYGGL 217
           R E +  I + + C   GR   N+  HD + W GD N+RI D     V   +K + +  L
Sbjct: 696 RNEDYKEITQ-KLCFPMGR---NVFSHDYVFWCGDFNYRI-DLTYEEVFYFVKRQDWKKL 750

Query: 218 WEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKR 277
            E DQL + K    + ++F EG + F PTYK+D  S  YDTS+K R PAWTDR+LW  K+
Sbjct: 751 LEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKK 810

Query: 278 QP---CAGP--------DTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLELK 323
            P    AG         D        +S     Y        SDH+PV    ++E++
Sbjct: 811 HPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQYYGRAELQASDHRPVLAIVEVEVQ 867


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
           sapiens]
          Length = 1258

 Score =  119 bits (299), Expect = 4e-27
 Identities = 90/330 (27%), Positives = 141/330 (42%), Gaps = 49/330 (14%)

Query: 14  LSIHVVTWNVASAAPPLDLSDLLQLNNRNLNLD---------IYVIGLQELNSGIISLLS 64
           +S+ + TWN+ S  PP +++           LD         IYV G QE + G      
Sbjct: 424 ISVFIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVFGTQENSVG------ 477

Query: 65  DAAFNDSWSSFLMDVLSPLSFIKVSHVRMQG---ILLLVFAKYQHLPYIQILSTKSTPTG 121
               +  W   L   L  L+ +    + MQ    I + V  K +H   I  +ST S  TG
Sbjct: 478 ----DREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTG 533

Query: 122 LFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNI 181
           +    GNKG V +     G     +NCHL        +R +++  IL + +   R + N 
Sbjct: 534 IANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLSLGDRQL-NA 592

Query: 182 LDHDL----IIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQ 237
            D  L    + WFGD+N+R+ D  +  +   I  + +  L   DQL++ ++   +   F 
Sbjct: 593 FDISLRFTHLFWFGDLNYRL-DMDIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFS 651

Query: 238 EGRLLFPPTYKFDRNSND-------YDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPA 290
           E  + FPPTY+++R S D         T  +   P+W DRILW+              P 
Sbjct: 652 EEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSY------------PE 699

Query: 291 SHFSLSLRGYSSHMTYGISDHKPVSGTFDL 320
           +H   +  G +  +    SDH PV GTF++
Sbjct: 700 THIICNSYGCTDDIV--TSDHSPVFGTFEV 727


>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
           sapiens]
          Length = 1188

 Score =  110 bits (275), Expect = 3e-24
 Identities = 86/343 (25%), Positives = 144/343 (41%), Gaps = 48/343 (13%)

Query: 1   MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRN---------LNLDIYVIG 51
           M ++    P+   ++I + TWN+ +A PP  ++       +          +  DIYVIG
Sbjct: 390 MKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIG 449

Query: 52  LQELNSGIISLLSDAAFNDSWSSFL---MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLP 108
            QE          D      W   L   +  ++ ++F  V+   +  I ++V AK +H  
Sbjct: 450 TQE----------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHEN 499

Query: 109 YIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRIL 168
            I  + T +  TG+    GNKG V +     G  +  +N HL        +R +++  IL
Sbjct: 500 RISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNIL 559

Query: 169 EMQNCEGRDI-PNILDHDL--IIWFGDMNFRIE--DFGLHFVRESIKNRCYGGLWEKDQL 223
                  + + P  + H    + WFGD+N+R++   +    + + IK + Y  L   DQL
Sbjct: 560 RFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQL 619

Query: 224 SIAKKHDPLLREFQEGRLLFPPTYKFDRNSND-------YDTSEKKRKPAWTDRILWRLK 276
              ++   +   F+E  + F PTY+F+R + D         T  K   P+W DR+LW+  
Sbjct: 620 LTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSY 679

Query: 277 RQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFD 319
                       P  H  +  + Y S      SDH PV  TF+
Sbjct: 680 ------------PLVH--VVCQSYGSTSDIMTSDHSPVFATFE 708


>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
           sapiens]
          Length = 1189

 Score =  110 bits (275), Expect = 3e-24
 Identities = 86/343 (25%), Positives = 144/343 (41%), Gaps = 48/343 (13%)

Query: 1   MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRN---------LNLDIYVIG 51
           M ++    P+   ++I + TWN+ +A PP  ++       +          +  DIYVIG
Sbjct: 391 MKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIG 450

Query: 52  LQELNSGIISLLSDAAFNDSWSSFL---MDVLSPLSFIKVSHVRMQGILLLVFAKYQHLP 108
            QE          D      W   L   +  ++ ++F  V+   +  I ++V AK +H  
Sbjct: 451 TQE----------DPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHEN 500

Query: 109 YIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRIL 168
            I  + T +  TG+    GNKG V +     G  +  +N HL        +R +++  IL
Sbjct: 501 RISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNIL 560

Query: 169 EMQNCEGRDI-PNILDHDL--IIWFGDMNFRIE--DFGLHFVRESIKNRCYGGLWEKDQL 223
                  + + P  + H    + WFGD+N+R++   +    + + IK + Y  L   DQL
Sbjct: 561 RFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQL 620

Query: 224 SIAKKHDPLLREFQEGRLLFPPTYKFDRNSND-------YDTSEKKRKPAWTDRILWRLK 276
              ++   +   F+E  + F PTY+F+R + D         T  K   P+W DR+LW+  
Sbjct: 621 LTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSY 680

Query: 277 RQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFD 319
                       P  H  +  + Y S      SDH PV  TF+
Sbjct: 681 ------------PLVH--VVCQSYGSTSDIMTSDHSPVFATFE 709


>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
          Length = 644

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 81/331 (24%), Positives = 141/331 (42%), Gaps = 48/331 (14%)

Query: 12  RRLSIHVVTWNVASAAP-PLDLSDLLQLNNRNLNLDIYVIGLQELNSGIISLLSDAAFND 70
           R +++ V TWN+      P  L + L     +   D+YVIG+QE            +   
Sbjct: 297 RNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQE----------GCSDRR 346

Query: 71  SWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKG 130
            W + L + L P  ++ +S      + + +F +   + +   +   +  T +      KG
Sbjct: 347 EWETRLQETLGP-HYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKG 405

Query: 131 GVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDH------ 184
            + I    +G     I  H         +RL  + R ++      R++P+   +      
Sbjct: 406 ALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALVLP-RNVPDTNPYRSSAAD 464

Query: 185 -----DLIIWFGDMNFRIEDFGLHFVRESIKNRCYG------GLWEKDQLSIAKKHDPLL 233
                D + WFGD NFR+   G   V +++   C G       L + DQL    +   + 
Sbjct: 465 VTTRFDEVFWFGDFNFRLS--GGRTVVDALL--CQGLVVDVPALLQHDQLIREMRKGSIF 520

Query: 234 REFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHF 293
           + FQE  + F P+YKFD   + YD++ K+R P++TDR+L+R + +   G   P+      
Sbjct: 521 KGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHK---GDICPV------ 571

Query: 294 SLSLRGYSSHMTYGISDHKPVSGTFDLELKP 324
                 YSS      SDH+PV G F ++++P
Sbjct: 572 -----SYSSCPGIKTSDHRPVYGLFRVKVRP 597


>gi|119943086 Tax1 (human T-cell leukemia virus type I) binding
           protein 1 isoform b [Homo sapiens]
          Length = 747

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 12/100 (12%)

Query: 349 YSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAW-------VGDSKVSCSDNLNQVYIDIS 401
           Y+ T      P DW+G++KVG     DY ++ W       V  S V+C       Y    
Sbjct: 36  YTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYY---- 91

Query: 402 NIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPL 441
            +P  + EF    Y      + G S PFQ    S  E+ L
Sbjct: 92  -LPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVEELL 130


>gi|21361682 Tax1 (human T-cell leukemia virus type I) binding
           protein 1 isoform a [Homo sapiens]
          Length = 789

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 12/100 (12%)

Query: 349 YSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAW-------VGDSKVSCSDNLNQVYIDIS 401
           Y+ T      P DW+G++KVG     DY ++ W       V  S V+C       Y    
Sbjct: 36  YTLTPYIHPHPKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYY---- 91

Query: 402 NIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPL 441
            +P  + EF    Y      + G S PFQ    S  E+ L
Sbjct: 92  -LPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVEELL 130


>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
          Length = 446

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 3/100 (3%)

Query: 336 EDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWV--GDSKVSCSDNL 393
           E  +    D+   Y+ T  F     DWIG+++VG +   +Y ++ WV       + S   
Sbjct: 29  EKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFMWVTLPIDLNNKSAKQ 88

Query: 394 NQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPP 433
            +V      +P  ++ +  CY       V G S PFQ  P
Sbjct: 89  QEVQFKAYYLPKDDEYYQFCYVDED-GVVRGASIPFQFRP 127


>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 2/72 (2%)

Query: 361 DWIGLYKVGLRDVNDYVSYAW--VGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNS 418
           DWIG++KV    V DY ++ W  V +S    S     V    S +P    +     Y N 
Sbjct: 46  DWIGIFKVEAACVRDYHTFVWSSVPESTTDGSPIHTSVQFQASYLPKPGAQLYQFRYVNR 105

Query: 419 LRSVVGISRPFQ 430
              V G S PFQ
Sbjct: 106 QGQVCGQSPPFQ 117


>gi|109702906 inositol polyphosphate-5-phosphatase A [Homo sapiens]
          Length = 412

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 22/79 (27%), Positives = 29/79 (36%), Gaps = 20/79 (25%)

Query: 243 FPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSS 302
           FPP+Y +  ++   +     R PAW DRIL               P A    L       
Sbjct: 323 FPPSYPYSEDARQGEQYMNTRCPAWCDRILMS-------------PSAKELVLRSESEEK 369

Query: 303 HMTYG-------ISDHKPV 314
            +TY        + DHKPV
Sbjct: 370 VVTYDHIGPNVCMGDHKPV 388


>gi|66392146 RNA U, small nuclear RNA export adaptor
           (phosphorylation regulated) [Homo sapiens]
          Length = 394

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 2/67 (2%)

Query: 230 DPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPP 289
           D  +R FQ       P   + R     D+SE+    +  D  LW+ KRQ C  P  P P 
Sbjct: 38  DSAMRAFQNTATACAPVSHY-RAVESVDSSEESFSDSDDDSCLWKRKRQKCFNP-PPKPE 95

Query: 290 ASHFSLS 296
              F  S
Sbjct: 96  PFQFGQS 102


>gi|62241001 conserved helix-loop-helix ubiquitous kinase [Homo
           sapiens]
          Length = 745

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 5/66 (7%)

Query: 295 LSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSD 354
           L L  YS  MTYGIS  K +    ++E K +  A + V     +  +E+ +M  ++   +
Sbjct: 489 LDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGV-----IGYLEDQIMSLHAEIME 543

Query: 355 FPSSPW 360
              SP+
Sbjct: 544 LQKSPY 549


>gi|27477111 step II splicing factor SLU7 [Homo sapiens]
          Length = 586

 Score = 29.3 bits (64), Expect = 7.6
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 6/64 (9%)

Query: 227 KKHDPLLREF--QEGRLLF-PPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGP 283
           KKH+ L +    +E RLL    T + D     Y++  + R+P   +   +R+KRQ    P
Sbjct: 520 KKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQ---RP 576

Query: 284 DTPI 287
           D P+
Sbjct: 577 DDPM 580


>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 2 [Homo sapiens]
          Length = 548

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 233 LREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASH 292
           LR   +  L  P  +++  +++D    E+KRK  + +     +K+ P +GP  P PP   
Sbjct: 269 LRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTY-ETFKSIMKKSPFSGPTDPRPPPRR 327

Query: 293 FSLSLRGYSS 302
            ++  R  +S
Sbjct: 328 IAVPSRSSAS 337


>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
           isoform 1 [Homo sapiens]
          Length = 551

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 233 LREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASH 292
           LR   +  L  P  +++  +++D    E+KRK  + +     +K+ P +GP  P PP   
Sbjct: 272 LRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTY-ETFKSIMKKSPFSGPTDPRPPPRR 330

Query: 293 FSLSLRGYSS 302
            ++  R  +S
Sbjct: 331 IAVPSRSSAS 340


>gi|219521893 coiled-coil transcriptional coactivator isoform 2
           [Homo sapiens]
          Length = 606

 Score = 28.9 bits (63), Expect = 9.9
 Identities = 10/21 (47%), Positives = 14/21 (66%)

Query: 361 DWIGLYKVGLRDVNDYVSYAW 381
           DWIG++KV    V DY ++ W
Sbjct: 46  DWIGIFKVEAACVRDYHTFVW 66


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,912,541
Number of Sequences: 37866
Number of extensions: 871517
Number of successful extensions: 1841
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1775
Number of HSP's gapped (non-prelim): 32
length of query: 448
length of database: 18,247,518
effective HSP length: 106
effective length of query: 342
effective length of database: 14,233,722
effective search space: 4867932924
effective search space used: 4867932924
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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