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Search of human proteins with 18379346
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo
sapiens]
(1222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo sapiens] 2477 0.0
gi|61743975 SORCS receptor 1 isoform b [Homo sapiens] 1592 0.0
gi|61743973 SORCS receptor 1 isoform a [Homo sapiens] 1521 0.0
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] 961 0.0
gi|4507157 sortilin-related receptor containing LDLR class A rep... 259 8e-69
gi|17149834 sortilin 1 preproprotein [Homo sapiens] 215 2e-55
gi|55741675 hypothetical protein LOC22889 [Homo sapiens] 44 0.001
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 44 0.001
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 41 0.008
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 41 0.008
gi|239751430 PREDICTED: hypothetical protein [Homo sapiens] 41 0.008
gi|239745934 PREDICTED: hypothetical protein XP_002343619 [Homo ... 41 0.008
gi|169162742 PREDICTED: hypothetical protein [Homo sapiens] 40 0.010
gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens] 40 0.010
gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens] 40 0.010
gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens] 40 0.010
gi|169204510 PREDICTED: hypothetical protein [Homo sapiens] 40 0.014
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens] 40 0.014
gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo ... 40 0.014
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 40 0.014
gi|145699105 connexin40.1 [Homo sapiens] 40 0.018
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 39 0.023
gi|239756550 PREDICTED: hypothetical protein XP_002344932 [Homo ... 39 0.030
gi|239745514 PREDICTED: hypothetical protein XP_002343509 [Homo ... 39 0.030
gi|182507165 thymus expressed gene 3-like [Homo sapiens] 39 0.040
gi|33286446 opioid growth factor receptor [Homo sapiens] 38 0.052
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 38 0.052
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 38 0.052
gi|194272140 dendrin [Homo sapiens] 38 0.052
gi|239748460 PREDICTED: hypothetical protein [Homo sapiens] 38 0.067
>gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo sapiens]
Length = 1222
Score = 2477 bits (6419), Expect = 0.0
Identities = 1222/1222 (100%), Positives = 1222/1222 (100%)
Query: 1 MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPLS 60
MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPLS
Sbjct: 1 MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPLS 60
Query: 61 PRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIP 120
PRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIP
Sbjct: 61 PRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIP 120
Query: 121 APAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAED 180
APAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAED
Sbjct: 121 APAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAED 180
Query: 181 LRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTY 240
LRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTY
Sbjct: 181 LRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTY 240
Query: 241 EKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLTFYIQSL 300
EKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLTFYIQSL
Sbjct: 241 EKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLTFYIQSL 300
Query: 301 LFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVR 360
LFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVR
Sbjct: 301 LFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVR 360
Query: 361 TTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYYVSYRRE 420
TTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYYVSYRRE
Sbjct: 361 TTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYYVSYRRE 420
Query: 421 AFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKS 480
AFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKS
Sbjct: 421 AFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKS 480
Query: 481 SRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVH 540
SRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVH
Sbjct: 481 SRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVH 540
Query: 541 CLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFISSDGGNT 600
CLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFISSDGGNT
Sbjct: 541 CLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFISSDGGNT 600
Query: 601 WRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALV 660
WRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALV
Sbjct: 601 WRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALV 660
Query: 661 EAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCVMGERKI 720
EAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCVMGERKI
Sbjct: 661 EAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCVMGERKI 720
Query: 721 FKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNPASPSKD 780
FKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNPASPSKD
Sbjct: 721 FKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNPASPSKD 780
Query: 781 CSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLVAEQGHN 840
CSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLVAEQGHN
Sbjct: 781 CSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLVAEQGHN 840
Query: 841 ATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLG 900
ATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLG
Sbjct: 841 ATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLG 900
Query: 901 SDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNSTKPLIT 960
SDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNSTKPLIT
Sbjct: 901 SDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNSTKPLIT 960
Query: 961 LDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPE 1020
LDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPE
Sbjct: 961 LDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPE 1020
Query: 1021 WRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQI 1080
WRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQI
Sbjct: 1021 WRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQI 1080
Query: 1081 VETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAV 1140
VETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAV
Sbjct: 1081 VETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAV 1140
Query: 1141 FLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRV 1200
FLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRV
Sbjct: 1141 FLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRV 1200
Query: 1201 IGGIATIANSESTKEIPNCTSV 1222
IGGIATIANSESTKEIPNCTSV
Sbjct: 1201 IGGIATIANSESTKEIPNCTSV 1222
>gi|61743975 SORCS receptor 1 isoform b [Homo sapiens]
Length = 1198
Score = 1592 bits (4123), Expect = 0.0
Identities = 761/1108 (68%), Positives = 912/1108 (82%), Gaps = 2/1108 (0%)
Query: 115 RGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAG 174
RG G RR R ERG+ + +P R G+RE +A
Sbjct: 93 RGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGTRER-DPDKAT 151
Query: 175 GSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRST 234
E+LRL ST+FALTGDSAHNQAMVHWSGHNSSVILILTKLYD+NLGS+TESSLWRST
Sbjct: 152 RFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRST 211
Query: 235 DYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLT 294
DYGTTYEKLNDKVGLKT+LSYLYV PTNKRKIMLL+DPE+ESS+LISSDEGATYQKYRL
Sbjct: 212 DYGTTYEKLNDKVGLKTILSYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLN 271
Query: 295 FYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADL 354
FYIQSLLFHPKQEDW+LAYS DQKLYSS +FGRRWQL+ E + PNRFYWSV G +KE DL
Sbjct: 272 FYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDL 331
Query: 355 VHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYY 414
VH+E RT DG++HYLTCR+Q C E R+ PF ID SL+VQD Y+F+Q+T+ GR YY
Sbjct: 332 VHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGGRPHYY 391
Query: 415 VSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLA 474
VSYRR AFAQ+KLPKY+LPKDMH+ISTDENQVFAAVQEWNQNDTYNLYISDTRG+YFTLA
Sbjct: 392 VSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLA 451
Query: 475 MENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDL 534
+EN++SSRG GNI+I+LYEVAGIKG+FLANKK+D+QVKT+ITYNKGRDWRLLQAPD DL
Sbjct: 452 LENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDTDL 511
Query: 535 RGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFIS 594
RG PVHCLLP+CSLHLHL++SENPY+SG I+SK+TAP ++VA+GNIG ELS TDI +F+S
Sbjct: 512 RGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSELSDTDISMFVS 571
Query: 595 SDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLF 654
SD GNTWRQIF+EE++V +LD GG LVAMKHT LP+RHLW+SFDEG SW KY FTS+PLF
Sbjct: 572 SDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLF 631
Query: 655 VDGALVEAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCV 714
VDG L E G ET IMTVFGHFS RSEWQLVKVDYKSIF R C +EDY+ W L +QGE C+
Sbjct: 632 VDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQGEACI 691
Query: 715 MGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNP 774
MG ++I+KKRK +C G+ ++G++ SEPCVC DF+CDYGYERH QC+PAFW+NP
Sbjct: 692 MGAKRIYKKRKSERKCMQGK-YAGAMESEPCVCTEADFDCDYGYERHSNGQCLPAFWFNP 750
Query: 775 ASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLV 834
+S SKDCSLGQSYLNSTGYR++VSNNCTDG+RE+YTAK Q CPGKAPRGL +VT DG+L
Sbjct: 751 SSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLT 810
Query: 835 AEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAY 894
AEQGHN T ++ +EEGD+QRT IQ+DFGDGIAVSY N S +EDGIKHVY++ GIF+VT
Sbjct: 811 AEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQ 870
Query: 895 AENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNS 954
+N+LGSD+AVL+LHV CP+EHVHL +PFV +NKEVN +AV+WPSQ+GTLTY WW+GN+
Sbjct: 871 VDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNN 930
Query: 955 TKPLITLDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYH 1014
T+PLITL+ SISF F +EG +TITVQV+AGNA++QDTK IAV+E F+S LSFSPNLD +
Sbjct: 931 TEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLSFSPNLDDY 990
Query: 1015 NPDIPEWRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNE 1074
NPDIPEWR+DIG VIK++LV+ T VP IL+AV PGLPT+AELF+LP ++ K +
Sbjct: 991 NPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLPYQDPAGENKRST 1050
Query: 1075 GDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVV 1134
DLEQI E L + LNQN V FELKPGV+V+V+ LT APLVD + HS SAMLMLLSVV
Sbjct: 1051 DDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVV 1110
Query: 1135 FVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDK 1194
FVGLAVF+IYKFKRKIP IN+YAQ+Q++KEQEMI VS SE+ P + ++ P +L+D+
Sbjct: 1111 FVGLAVFVIYKFKRKIPGINVYAQMQNEKEQEMISPVSHSESRPNVPQTELRRPGQLIDE 1170
Query: 1195 ELDTRVIGGIATIANSESTKEIPNCTSV 1222
++++++IG I+ +A ++STKEIP +V
Sbjct: 1171 KVESQLIGSISIVAENQSTKEIPTYVNV 1198
>gi|61743973 SORCS receptor 1 isoform a [Homo sapiens]
Length = 1168
Score = 1521 bits (3938), Expect = 0.0
Identities = 727/1036 (70%), Positives = 858/1036 (82%), Gaps = 2/1036 (0%)
Query: 115 RGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAG 174
RG G RR R ERG+ + +P R G+RE +A
Sbjct: 93 RGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGTRER-DPDKAT 151
Query: 175 GSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRST 234
E+LRL ST+FALTGDSAHNQAMVHWSGHNSSVILILTKLYD+NLGS+TESSLWRST
Sbjct: 152 RFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRST 211
Query: 235 DYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLT 294
DYGTTYEKLNDKVGLKT+LSYLYV PTNKRKIMLL+DPE+ESS+LISSDEGATYQKYRL
Sbjct: 212 DYGTTYEKLNDKVGLKTILSYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLN 271
Query: 295 FYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADL 354
FYIQSLLFHPKQEDW+LAYS DQKLYSS +FGRRWQL+ E + PNRFYWSV G +KE DL
Sbjct: 272 FYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDL 331
Query: 355 VHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYY 414
VH+E RT DG++HYLTCR+Q C E R+ PF ID SL+VQD Y+F+Q+T+ GR YY
Sbjct: 332 VHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGGRPHYY 391
Query: 415 VSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLA 474
VSYRR AFAQ+KLPKY+LPKDMH+ISTDENQVFAAVQEWNQNDTYNLYISDTRG+YFTLA
Sbjct: 392 VSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLA 451
Query: 475 MENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDL 534
+EN++SSRG GNI+I+LYEVAGIKG+FLANKK+D+QVKT+ITYNKGRDWRLLQAPD DL
Sbjct: 452 LENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDTDL 511
Query: 535 RGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFIS 594
RG PVHCLLP+CSLHLHL++SENPY+SG I+SK+TAP ++VA+GNIG ELS TDI +F+S
Sbjct: 512 RGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSELSDTDISMFVS 571
Query: 595 SDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLF 654
SD GNTWRQIF+EE++V +LD GG LVAMKHT LP+RHLW+SFDEG SW KY FTS+PLF
Sbjct: 572 SDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLF 631
Query: 655 VDGALVEAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCV 714
VDG L E G ET IMTVFGHFS RSEWQLVKVDYKSIF R C +EDY+ W L +QGE C+
Sbjct: 632 VDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQGEACI 691
Query: 715 MGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNP 774
MG ++I+KKRK +C G+ ++G++ SEPCVC DF+CDYGYERH QC+PAFW+NP
Sbjct: 692 MGAKRIYKKRKSERKCMQGK-YAGAMESEPCVCTEADFDCDYGYERHSNGQCLPAFWFNP 750
Query: 775 ASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLV 834
+S SKDCSLGQSYLNSTGYR++VSNNCTDG+RE+YTAK Q CPGKAPRGL +VT DG+L
Sbjct: 751 SSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLT 810
Query: 835 AEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAY 894
AEQGHN T ++ +EEGD+QRT IQ+DFGDGIAVSY N S +EDGIKHVY++ GIF+VT
Sbjct: 811 AEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQ 870
Query: 895 AENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNS 954
+N+LGSD+AVL+LHV CP+EHVHL +PFV +NKEVN +AV+WPSQ+GTLTY WW+GN+
Sbjct: 871 VDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNN 930
Query: 955 TKPLITLDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYH 1014
T+PLITL+ SISF F +EG +TITVQV+AGNA++QDTK IAV+E F+S LSFSPNLD +
Sbjct: 931 TEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLSFSPNLDDY 990
Query: 1015 NPDIPEWRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNE 1074
NPDIPEWR+DIG VIK++LV+ T VP IL+AV PGLPT+AELF+LP ++ K +
Sbjct: 991 NPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLPYQDPAGENKRST 1050
Query: 1075 GDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVV 1134
DLEQI E L + LNQN V FELKPGV+V+V+ LT APLVD + HS SAMLMLLSVV
Sbjct: 1051 DDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVV 1110
Query: 1135 FVGLAVFLIYKFKRKI 1150
FVGLAVF+IYKFKR++
Sbjct: 1111 FVGLAVFVIYKFKRRV 1126
>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
Length = 1159
Score = 961 bits (2485), Expect = 0.0
Identities = 504/1150 (43%), Positives = 720/1150 (62%), Gaps = 38/1150 (3%)
Query: 39 ATGGPG---RPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQGG 95
A+ GPG R +P + PP P SPR+ L A AA GR P G
Sbjct: 9 ASKGPGPTARAPSPGAPPP---PRSPRSRPLLLLLLLLGACGAA--GRSPEP-------G 56
Query: 96 GRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSR 155
G Q+ SP R G GG R R P G + AP G
Sbjct: 57 RLGPHAQLTRVPRSPPAGRAEPG-------GGEDRQARGTEPGAP--GPSPGPAPGPGED 107
Query: 156 GSRPLAKGSREEVKAPRAGGSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILT 215
G+ P A R E AP AG ++ + L STSF L GD+ HNQAMVHW+G NSSVILILT
Sbjct: 108 GA-PAAGYRRWERAAPLAGVASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILT 166
Query: 216 KLYDFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDP--E 273
K Y ++G V ESSLWRS+D+GT+Y KL + G+ TV+ Y+ PTNKRK++L+S +
Sbjct: 167 KYYHADMGKVLESSLWRSSDFGTSYTKLTLQPGVTTVIDNFYICPTNKRKVILVSSSLSD 226
Query: 274 MESSILISSDEGATYQKYRLTFYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMH 333
+ S+ +S+DEGAT+QK + F++++L+FHPK+ED VLAY+ + KLY S D G++W L+
Sbjct: 227 RDQSLFLSADEGATFQKQPIPFFVETLIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQ 286
Query: 334 ERITPNRFYWSVAGLDKEADLVHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISS 393
ER+T + +WSV+G+D + DLVH+E + G Y+TC I C+E + PFA ID S
Sbjct: 287 ERVTKDHVFWSVSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGS 346
Query: 394 LVVQDEYIFIQVTTSGRASYYVSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEW 453
L VQD+YIF + T++ + YYVSYRR F +KLPKY+LPKD+ IISTDE+QVF AVQEW
Sbjct: 347 LTVQDDYIFFKATSANQTKYYVSYRRNEFVLMKLPKYALPKDLQIISTDESQVFVAVQEW 406
Query: 454 NQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVK 513
Q DTYNLY SD RG+ + L +++++SSR +++I++ EV G+KG+FLAN+K+D +V
Sbjct: 407 YQMDTYNLYQSDPRGVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVM 466
Query: 514 TYITYNKGRDWRLLQAPDVDLRGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKETAPGL 573
T ITYNKGRDW L+ P +D+ G P +C P C LHLHL+ ++NPY SG + +K+TAPGL
Sbjct: 467 TLITYNKGRDWDYLRPPSMDMNGKPTNCKPPDCHLHLHLRWADNPYVSGTVHTKDTAPGL 526
Query: 574 VVATGNIGPELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHL 633
++ GN+G +L ++I+SD G+TWRQ+F+EE+++ +LD GG +VA+K T +P++ L
Sbjct: 527 IMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKIL 586
Query: 634 WVSFDEGHSWDKYGFTSVPLFVDGALVEAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFS 693
S DEG +W + FTS +FVDG L E G ET +MTVFGH S RS+W+LVKVD++ FS
Sbjct: 587 KFSVDEGLTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFS 646
Query: 694 RHCTKEDYQTWHLLN-QGEPCVMGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDF 752
R C +EDY +W L N QG+ C+MG+++ F+KRK + C GR + ++ S C C + DF
Sbjct: 647 RQCGEEDYSSWELSNLQGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDF 706
Query: 753 ECDYGYERHGESQ-----CVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLRE 807
CDYG+ER S+ C FW+NP SP DC+LGQ+Y +S GYR++VSN C G+
Sbjct: 707 LCDYGFERSSSSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDM 766
Query: 808 KYTAKAQMCPGKAPRGLHVVTTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGIAV 867
+ + CP PRGL V + G + F++ E+GD+ T Q+D GDG
Sbjct: 767 QQSQVQLQCPLTPPRGLQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKA 826
Query: 868 SYANFSPIEDGIKHVYKSAGIFQVTAYAENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIR 927
Y N + + I+H Y+S GI++V+ AEN G D AVLF+ V P++ ++L V V
Sbjct: 827 MYVNLTLTGEPIRHRYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGL 886
Query: 928 NKEVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTDTITVQVAAGNAL 987
N+EVN++AV+ P ++WW G+S +PL++LD+S++ F G +TVQ A GN++
Sbjct: 887 NQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSV 946
Query: 988 IQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPEWRKDIGNVIKRALVKVTSVPEDQILIA 1047
+QD++ + V + FQ L FS LD +NP+ PEWR+D+G V+ R L K TSVP++ ++
Sbjct: 947 LQDSRVLRVLDQFQVMPLQFSKELDAYNPNTPEWREDVGLVVTRLLSKETSVPQELLVTV 1006
Query: 1048 VFPGLPTSAELFILPPKNLTERRKGNEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYV 1107
V PGLPT A+L++L P R++ D + + + LN + F L+ GV+V+V +
Sbjct: 1007 VKPGLPTLADLYVLLPPPRPTRKRSLSSD--KRLAAIQQVLNAQKISFLLRGGVRVLVAL 1064
Query: 1108 TQL-TLAPLVDSSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRKIPWINIYAQVQHDKEQE 1166
T A + G+ + +L ++ + G F++YKFKRK P +YAQ+ ++KEQE
Sbjct: 1065 RDTGTGAEQLGGGGGYWAVVVLFVIGLFAAG--AFILYKFKRKRPGRTVYAQMHNEKEQE 1122
Query: 1167 MIGSVSQSEN 1176
M VS SE+
Sbjct: 1123 MTSPVSHSED 1132
>gi|4507157 sortilin-related receptor containing LDLR class A
repeats preproprotein [Homo sapiens]
Length = 2214
Score = 259 bits (663), Expect = 8e-69
Identities = 200/728 (27%), Positives = 347/728 (47%), Gaps = 73/728 (10%)
Query: 129 RRSRRAQPPITQERGDAWATA-PADGSRGSRPLAKG-SREEVKAPRAGGSAAEDLRLPST 186
+R P+ Q+RG P + +R A+G SR + K R SAA
Sbjct: 33 QRLHGGSAPLPQDRGFLVVQGDPRELRLWARGDARGASRADEKPLRRKRSAALQPEPIKV 92
Query: 187 SFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTYEKLNDK 246
++ + +HNQ +VHW+G S+VI+ L + L S ++ S DYG +++K++DK
Sbjct: 93 YGQVSLNDSHNQMVVHWAGEKSNVIVALAR-DSLALARPKSSDVYVSYDYGKSFKKISDK 151
Query: 247 VGL------KTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLTFYIQSL 300
+ + V++ Y +P + ++ + + I+ D T Q + + F L
Sbjct: 152 LNFGLGNRSEAVIAQFYHSPADNKRYIFAD--AYAQYLWITFDFCNTLQGFSIPFRAADL 209
Query: 301 LFHPKQEDWVLAYSL---DQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHM 357
L H K + +L + +++L+ S DFG+ W ++ E + F W + DK + +++
Sbjct: 210 LLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHV--KSFSWGIDPYDKP-NTIYI 266
Query: 358 EVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQ--------DEYIF----IQV 405
E GY+ RS F +S + ++++ D+Y+F + +
Sbjct: 267 ERHEPSGYSTVF-----------RSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHL 315
Query: 406 TTSGRAS---YYVSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLY 462
S + S +VS+ R+ + + +I E+QVF V + N+ NLY
Sbjct: 316 LGSEQQSSVQLWVSFGRKPMRAAQFVTRHPINEYYIADASEDQVFVCVS--HSNNRTNLY 373
Query: 463 ISDTRGIYFTLAMENIK--SSRGLMGNIII---------ELYEVAGIKGIFLAN----KK 507
IS+ G+ F+L++EN+ S G + ++ + + V G++G+++A
Sbjct: 374 ISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSM 433
Query: 508 VDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHC-LLPFCSLHLHLQLSENPYSSGR--- 563
++ +++ IT++KG W LQAP G ++C L CSLHL +LS+ R
Sbjct: 434 NEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMP 493
Query: 564 ISSKETAPGLVVATGNIGPELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAM 623
I SKE+APGL++ATG++G L+ + V+ISS G WR+ + + D GG + A+
Sbjct: 494 ILSKESAPGLIIATGSVGKNLA-SKTNVYISSSAGARWREALPGPHYYTWGDHGGIITAI 552
Query: 624 KHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALVEAGMETHIMTVFGHFSLR-SEWQ 682
+ L S +EG +W + F+ P+FV G L E G ++ + T+FG W
Sbjct: 553 AQG-METNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIFGSNKENVHSWL 611
Query: 683 LVKVDYKSIFSRHCTKEDYQTWHLLNQ-GEPCVMGERKIFKKRKPGAQCALGRDHSGSVV 741
+++V+ CT+ DY+ W ++ G C++G + +FK+R P A C G D VV
Sbjct: 612 ILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVV 671
Query: 742 SEPCVCANWDFECDYGYERHGE---SQCV--PAFWYNPASPSKDCSLGQSYLNSTGYRRI 796
C C D+ECD+G++ + CV P F SP C +G +Y + GYR+I
Sbjct: 672 VSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGSTYRRTRGYRKI 731
Query: 797 VSNNCTDG 804
+ C+ G
Sbjct: 732 SGDTCSGG 739
>gi|17149834 sortilin 1 preproprotein [Homo sapiens]
Length = 831
Score = 215 bits (547), Expect = 2e-55
Identities = 176/699 (25%), Positives = 333/699 (47%), Gaps = 62/699 (8%)
Query: 143 GDAWA--TAPADGS--RGSRPLAKGSREEVKAPRAGGSAAEDLRLPSTSFALTGDSAHNQ 198
G +W A A G+ RG R E+ + R A +L + + D
Sbjct: 55 GVSWGLRAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVA---KLANNTHQHVFDDLRGS 111
Query: 199 AMVHWSGHNSSVILILTKLY-DFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSY-- 255
+ W G ++ VIL+LT + + + +S L+RS DYG ++ + D + + +
Sbjct: 112 VSLSWVGDSTGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFG 171
Query: 256 LYVNPTNKRKIMLLSDPEMESS---ILISSDEGATYQKYRLTFY-IQSLLFHPKQEDWVL 311
+ + P N K++L ++ S I SSD + + L F+ + +++ P+ D++L
Sbjct: 172 MAIGPENSGKVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLL 231
Query: 312 AYSLDQKLYSSMDFGRRWQLMHERITPNR-------FYWSVAGLDKEADLVHMEV-RTTD 363
A S + L+ S +FG +W+ +H+ + + F+ + A +ADL +E+ RT+D
Sbjct: 232 ALSTENGLWVSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALELWRTSD 291
Query: 364 GYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYYVSYRREAFA 423
+ T ++ + G R + S + +D I V+T + + ++
Sbjct: 292 LGKSFKTIGVKIYS----FGLGGRFLFASVMADKDTTRRIHVSTD---------QGDTWS 338
Query: 424 QIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAME-NIKSSR 482
+LP + I++ +++ VF V E ++ SD RGI ++ +++ ++ ++
Sbjct: 339 MAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTT 398
Query: 483 GLMGNIIIELYEVAGIKGIFLANK-KVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHC 541
G G + V ++G+++ + D+ ++T IT+++G W L+ P+ +
Sbjct: 399 G--GET--DFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWTHLRKPENSECDATAKN 454
Query: 542 LLPFCSLHLHLQLSENPYSSGRIS--SKETAPGLVVATGNIGPELSYTDIGVFISSDGGN 599
CSLH+H S + + ++ S+ A G+V+A G++G +S V+IS DGG
Sbjct: 455 KNE-CSLHIHASYSISQKLNVPMAPLSEPNAVGIVIAHGSVGDAISVMVPDVYISDDGGY 513
Query: 600 TWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGAL 659
+W ++ + + LD GG +VA++H+ P+ + S DEG W Y FT P++ G
Sbjct: 514 SWTKMLEGPHYYTILDSGGIIVAIEHSSRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLA 573
Query: 660 VEAGMETHIMTVFGHFS--LRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEP----- 712
E G + ++++G L S+W +D+K I R+C ++DY W L + +P
Sbjct: 574 SEPGARSMNISIWGFTESFLTSQWVSYTIDFKDILERNCEEKDYTIW-LAHSTDPEDYED 632
Query: 713 -CVMGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYER-HGESQCVPAF 770
C++G ++ F + + + C GRD+ + C+C+ DF CD+GY R +S+CV
Sbjct: 633 GCILGYKEQFLRLRKSSVCQNGRDYVVTKQPSICLCSLEDFLCDFGYYRPENDSKCVE-- 690
Query: 771 WYNPASPSKD---CSLG-QSYLNSTGYRRIVSNNCTDGL 805
P D C G + +L + GYR+I + C G+
Sbjct: 691 --QPELKGHDLEFCLYGREEHLTTNGYRKIPGDKCQGGV 727
>gi|55741675 hypothetical protein LOC22889 [Homo sapiens]
Length = 614
Score = 43.9 bits (102), Expect = 0.001
Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 19/132 (14%)
Query: 9 PAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPAS-----------RPPALS 57
PA G P V T + T V A GGP PAAP +P
Sbjct: 396 PALPTGVPPVPTQYPI--TQVQPPASTGQSPMGGPFIPAAPVKTALPAGPQPQPQPQPPL 453
Query: 58 PLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAG----- 112
P P+A ++ EEL R + +LG + GP + G G + ++E G+ PA
Sbjct: 454 PSQPQAQKRRFTEELPDERESGLLGYQHGPIHMTNLGTGFSSQNEIEGAGSKPASSSGKE 513
Query: 113 -ERRGRGIPAPA 123
ER + +P PA
Sbjct: 514 RERDRQLMPPPA 525
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 43.5 bits (101), Expect = 0.001
Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 12/107 (11%)
Query: 38 DATGGPGRPAA--PAS--RPPALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQ- 92
+A GG GRP A PAS R P L+ A +E A + L RR GP P
Sbjct: 1330 EAPGGQGRPEAGRPASEARAPGLAAADAADAARAGGKEAPRAAAGSELCRREGPGAAPAF 1389
Query: 93 --QGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPP 137
GGG G ++ E + AG R P P GGA + A P
Sbjct: 1390 AGPGGGGSGALEAEGRAGARAGPR-----PGPRPPGGAPARKAAVAP 1431
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 40.8 bits (94), Expect = 0.008
Identities = 50/156 (32%), Positives = 67/156 (42%), Gaps = 23/156 (14%)
Query: 40 TGGPGRPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRA-----GPELLPQQG 94
T GP + PA P A P + + P E +A A G R GPE P +
Sbjct: 727 TDGPKGASGPAGPPGAQGPPGLQGM----PGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 782
Query: 95 GGRGGEMQVEAGGTSPA-GERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPAD- 152
GGRG + G + A GE+ G P PA GAR + ERG+ PA
Sbjct: 783 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA-------PGERGETGPPGPAGF 835
Query: 153 -GSRGS--RPLAKGSREEVKAPRAGGSAAEDLRLPS 185
G G+ +P AKG E+ +A + G + A + PS
Sbjct: 836 AGPPGADGQPGAKG--EQGEAGQKGDAGAPGPQGPS 869
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 40.8 bits (94), Expect = 0.008
Identities = 50/156 (32%), Positives = 67/156 (42%), Gaps = 23/156 (14%)
Query: 40 TGGPGRPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRA-----GPELLPQQG 94
T GP + PA P A P + + P E +A A G R GPE P +
Sbjct: 658 TDGPKGASGPAGPPGAQGPPGLQGM----PGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 713
Query: 95 GGRGGEMQVEAGGTSPA-GERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPAD- 152
GGRG + G + A GE+ G P PA GAR + ERG+ PA
Sbjct: 714 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA-------PGERGETGPPGPAGF 766
Query: 153 -GSRGS--RPLAKGSREEVKAPRAGGSAAEDLRLPS 185
G G+ +P AKG E+ +A + G + A + PS
Sbjct: 767 AGPPGADGQPGAKG--EQGEAGQKGDAGAPGPQGPS 800
>gi|239751430 PREDICTED: hypothetical protein [Homo sapiens]
Length = 303
Score = 40.8 bits (94), Expect = 0.008
Identities = 51/160 (31%), Positives = 63/160 (39%), Gaps = 26/160 (16%)
Query: 41 GGPGRPAAPASRPPA-LSPLSP----------RAVASQWPEELASARRAAVLGRRAGPEL 89
GGPG+ AA A PPA +P P R AS P + + AAV AGP
Sbjct: 98 GGPGQVAAAAPAPPASWAPPQPGRRPTCPGCCRGAASGAPRWVRTWAAAAV---AAGPGR 154
Query: 90 LPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATA 149
Q R AG +S AG RG + A G RS A RG A A++
Sbjct: 155 SAPQREPRAAWAACPAGPSSAAGPERGH-VSCAADEPGTERSGAA-----AARGSAGASS 208
Query: 150 PADGSRGSRP------LAKGSREEVKAPRAGGSAAEDLRL 183
G+ G+ L G K P AGG+A +L
Sbjct: 209 RGRGALGAWARHSAVRLDSGRGWRGKTPGAGGAAERGAQL 248
>gi|239745934 PREDICTED: hypothetical protein XP_002343619 [Homo
sapiens]
Length = 303
Score = 40.8 bits (94), Expect = 0.008
Identities = 51/160 (31%), Positives = 63/160 (39%), Gaps = 26/160 (16%)
Query: 41 GGPGRPAAPASRPPA-LSPLSP----------RAVASQWPEELASARRAAVLGRRAGPEL 89
GGPG+ AA A PPA +P P R AS P + + AAV AGP
Sbjct: 98 GGPGQVAAAAPAPPASWAPPQPGRRPTCPGCCRGAASGAPRWVRTWAAAAV---AAGPGR 154
Query: 90 LPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATA 149
Q R AG +S AG RG + A G RS A RG A A++
Sbjct: 155 SAPQREPRAAWAACPAGPSSAAGPERGH-VSCAADEPGTERSGAA-----AARGSAGASS 208
Query: 150 PADGSRGSRP------LAKGSREEVKAPRAGGSAAEDLRL 183
G+ G+ L G K P AGG+A +L
Sbjct: 209 RGRGALGAWARHSAVRLDSGRGWRGKTPGAGGAAERGAQL 248
>gi|169162742 PREDICTED: hypothetical protein [Homo sapiens]
Length = 382
Score = 40.4 bits (93), Expect = 0.010
Identities = 58/206 (28%), Positives = 73/206 (35%), Gaps = 51/206 (24%)
Query: 9 PAGRPGAPLVRTGLLLLSTWVLAGA--EITWDA-TGGPGRPAAPASR------PPALSPL 59
P+ P P TGL S GA W +GG G P + PPA P
Sbjct: 9 PSTTPSPPQDPTGLTCPSPGRKGGAWQVAAWPVVSGGAGHPLFSSLLLDSPPWPPACPP- 67
Query: 60 SPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGE---MQVEAGGT-------- 108
+P A AS P AR ++L LP+ GGGRGG+ ++ GGT
Sbjct: 68 TPPAKASVQPRH--PARYISLLRYSEAAAPLPRGGGGRGGQDISLRARRGGTRTGDRGAE 125
Query: 109 ---------------------SPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWA 147
+ G RGR P P L R + RG+A
Sbjct: 126 LTRPQSLLARGLGPNWLAAAAANQGLGRGRDQPRPGPLPSLRAQEAGR------RGNAVG 179
Query: 148 TAPADGSRGSRPLAKGS-REEVKAPR 172
GSR P A+GS R + PR
Sbjct: 180 GVTGTGSRLHAPGARGSQRPSARGPR 205
>gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]
Length = 170
Score = 40.4 bits (93), Expect = 0.010
Identities = 47/154 (30%), Positives = 61/154 (39%), Gaps = 33/154 (21%)
Query: 16 PLVRTGLLLLSTWVLA--GAEITWDATGGPGRPAAPASRPPALSPLSPRAVASQWPEELA 73
P + T L LL W+L GA + + P PA PA A +P P A PE A
Sbjct: 12 PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCA-----PEPAA 66
Query: 74 SARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRR 133
S AGPE P + G G E G + GE G G PA A ++
Sbjct: 67 SP---------AGPE-EPGEPAGLG-----ELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111
Query: 134 AQPPITQERGDAWATAPADGSRGSRPLAKGSREE 167
A+ Q+ DG +G P ++G EE
Sbjct: 112 ARQEEEQD---------LDGEKG--PSSEGPEEE 134
>gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]
Length = 177
Score = 40.4 bits (93), Expect = 0.010
Identities = 47/154 (30%), Positives = 61/154 (39%), Gaps = 33/154 (21%)
Query: 16 PLVRTGLLLLSTWVLA--GAEITWDATGGPGRPAAPASRPPALSPLSPRAVASQWPEELA 73
P + T L LL W+L GA + + P PA PA A +P P A PE A
Sbjct: 12 PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCA-----PEPAA 66
Query: 74 SARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRR 133
S AGPE P + G G E G + GE G G PA A ++
Sbjct: 67 SP---------AGPE-EPGEPAGLG-----ELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111
Query: 134 AQPPITQERGDAWATAPADGSRGSRPLAKGSREE 167
A+ Q+ DG +G P ++G EE
Sbjct: 112 ARQEEEQD---------LDGEKG--PSSEGPEEE 134
>gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]
Length = 204
Score = 40.4 bits (93), Expect = 0.010
Identities = 47/154 (30%), Positives = 61/154 (39%), Gaps = 33/154 (21%)
Query: 16 PLVRTGLLLLSTWVLA--GAEITWDATGGPGRPAAPASRPPALSPLSPRAVASQWPEELA 73
P + T L LL W+L GA + + P PA PA A +P P A PE A
Sbjct: 12 PALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCA-----PEPAA 66
Query: 74 SARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRR 133
S AGPE P + G G E G + GE G G PA A ++
Sbjct: 67 SP---------AGPE-EPGEPAGLG-----ELGEPAGPGEPEGPGDPAAAPAEAEEQAVE 111
Query: 134 AQPPITQERGDAWATAPADGSRGSRPLAKGSREE 167
A+ Q+ DG +G P ++G EE
Sbjct: 112 ARQEEEQD---------LDGEKG--PSSEGPEEE 134
>gi|169204510 PREDICTED: hypothetical protein [Homo sapiens]
Length = 257
Score = 40.0 bits (92), Expect = 0.014
Identities = 40/127 (31%), Positives = 46/127 (36%), Gaps = 13/127 (10%)
Query: 40 TGGPGR-PAAPAS-RPPALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGR 97
T GP P AP RPP SP + P L RRA LGR+ G + G +
Sbjct: 116 TAGPTPIPRAPRPWRPPPPSPGRVGVLLEVLPRSLLQIRRALALGRQRGSYRICANGFYK 175
Query: 98 GGE--------MQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRA---QPPITQERGDAW 146
+ V A G RRG P +LG RR RA PP DA
Sbjct: 176 QSRKTPVCCRVLLVRARGKPGCSPRRGAAGPGACELGEGRRLPRAPGPSPPPLPASADAA 235
Query: 147 ATAPADG 153
P G
Sbjct: 236 GRLPPGG 242
>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
Length = 257
Score = 40.0 bits (92), Expect = 0.014
Identities = 51/179 (28%), Positives = 63/179 (35%), Gaps = 34/179 (18%)
Query: 40 TGGPGRPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRAGP------------ 87
T P A P A PL A ++ W ++R A GRRAGP
Sbjct: 56 TVAPAASAGSQEHPGAGGPLCFPARSAAWGPPARASRAA---GRRAGPAGPPCRAPGRGR 112
Query: 88 ----ELLPQQGGGRGGEMQVE-AGGTSPAGERRGRGIPA---PAKLGGA---------RR 130
P G RG VE AGG + A R +PA P GG RR
Sbjct: 113 AAATRRSPAPGTARGSPAGVERAGGATAASSAGTRSVPARRLPPPCGGTSLGAGSRALRR 172
Query: 131 SRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAEDLRLPSTSFA 189
A P + WA P G+ RP A G+ A A +AA + P + A
Sbjct: 173 PGSAALPRSPSSSRRWAAMPGPGA--PRPGAPGTWPVGFAVAAPPAAAASVAPPPPAVA 229
>gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo
sapiens]
Length = 193
Score = 40.0 bits (92), Expect = 0.014
Identities = 44/162 (27%), Positives = 57/162 (35%), Gaps = 33/162 (20%)
Query: 30 LAGAE----ITWDATGGPGRPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRA 85
L+GAE + A P + RP SP P A PE + R+
Sbjct: 41 LSGAEGKELLAAQAAHRPRQQQRQQQRPRPRSP-DPAARGQHVPE---------LRSRKP 90
Query: 86 GPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDA 145
GP ++GG G P G+P P GG RR R PP
Sbjct: 91 GPAARTEEGGDVTGRPWQPPLLPPP-------GVPTPGNRGGERRGERRAPP-------- 135
Query: 146 WATAPADGSRGSRPLAKG-SREEVKAPRAGGSAAEDLRLPST 186
PA RGS A+G +R E + P G A + P +
Sbjct: 136 ---RPAGAPRGSPMAARGRARGEAEPPALGAGACDSRNQPDS 174
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 40.0 bits (92), Expect = 0.014
Identities = 42/133 (31%), Positives = 49/133 (36%), Gaps = 15/133 (11%)
Query: 43 PGRPAAPASRPPALSPLSPRAVASQWPEELASARR---AAVLGRRAGPELLPQQGGGRGG 99
P P A S PP P +P + A AAV G GP+ P GG +GG
Sbjct: 151 PTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGG 210
Query: 100 EMQVEAGGTSPAGE---RRGRGIPAPAKLGGA--RRSRRAQPPITQERGDAWATAPADGS 154
+M GG P G G P P GG R R+ PP Q+ P G
Sbjct: 211 KM---PGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQ----GPPPGG 263
Query: 155 RGSRPLAKGSREE 167
G R K S E
Sbjct: 264 PGGRSEEKISDSE 276
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 39.7 bits (91), Expect = 0.018
Identities = 32/111 (28%), Positives = 42/111 (37%), Gaps = 8/111 (7%)
Query: 83 RRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAP--AKLGG------ARRSRRA 134
RR GP P G E T G R G PAP A+ GG R SR +
Sbjct: 226 RRPGPPTSPSIRKQSGASGHAEGRRTDEEGGREEEGAPAPPGARAGGEGAGSPRRTSRVS 285
Query: 135 QPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAEDLRLPS 185
+ ++ T+ A G +P + RE + PR GS + PS
Sbjct: 286 GHTKIPDEDESEVTSSASEKLGRQPRGRPHREAAQDPRGSGSEEQPSAAPS 336
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 39.3 bits (90), Expect = 0.023
Identities = 36/143 (25%), Positives = 51/143 (35%), Gaps = 11/143 (7%)
Query: 27 TWVLAGAEITWD--ATGGPGRPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRR 84
+W LAG + + A G + P + +S + A+ W A + G
Sbjct: 1315 SWALAGNQAIGELWAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGAG 1374
Query: 85 AG--------PELLPQQGGGR-GGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQ 135
AG ++ Q GGG G GG+ P E + G + A GG
Sbjct: 1375 AGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSML 1434
Query: 136 PPITQERGDAWATAPADGSRGSR 158
P Q G +WA S GSR
Sbjct: 1435 GPEDQSSGRSWADTADQASGGSR 1457
>gi|239756550 PREDICTED: hypothetical protein XP_002344932 [Homo
sapiens]
Length = 177
Score = 38.9 bits (89), Expect = 0.030
Identities = 58/179 (32%), Positives = 67/179 (37%), Gaps = 29/179 (16%)
Query: 3 AARTERPAGRPG---APLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPL 59
+ART RPA G P R G L +GG A P R AL
Sbjct: 17 SARTVRPAMLAGLGPGPSPRRGRL---------------PSGGLRLRARPGRR--ALGLP 59
Query: 60 SPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGI 119
SP +A+ ASA V RRA P +P RG + E SPAG R
Sbjct: 60 SPLELAAPSLVPNASASPRPVSCRRAPPRPVPGAARWRG---RPEPRPGSPAGPAPTRAR 116
Query: 120 PAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAA 178
P LG RS A P +ER DG R RP A+G E V + G A
Sbjct: 117 P----LGAPGRS--APPARRRERELGTDARVGDGERELRPDARGRAEAVCSDHVGAGCA 169
>gi|239745514 PREDICTED: hypothetical protein XP_002343509 [Homo
sapiens]
Length = 177
Score = 38.9 bits (89), Expect = 0.030
Identities = 58/179 (32%), Positives = 67/179 (37%), Gaps = 29/179 (16%)
Query: 3 AARTERPAGRPG---APLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPL 59
+ART RPA G P R G L +GG A P R AL
Sbjct: 17 SARTVRPAMLAGLGPGPSPRRGRL---------------PSGGLRLRARPGRR--ALGLP 59
Query: 60 SPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGI 119
SP +A+ ASA V RRA P +P RG + E SPAG R
Sbjct: 60 SPLELAAPSLVPNASASPRPVSCRRAPPRPVPGAARWRG---RPEPRPGSPAGPAPTRAR 116
Query: 120 PAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAA 178
P LG RS A P +ER DG R RP A+G E V + G A
Sbjct: 117 P----LGAPGRS--APPARRRERELGTDARVGDGERELRPDARGRAEAVCSDHVGAGCA 169
>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
Length = 629
Score = 38.5 bits (88), Expect = 0.040
Identities = 62/230 (26%), Positives = 79/230 (34%), Gaps = 54/230 (23%)
Query: 3 AARTERPAGRP----------GAPLVRTGLLLLSTWVLAGA----EITWDATGGPGRPAA 48
A R+ RP GRP G PL LL GA A GGP R +
Sbjct: 225 AMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNS 284
Query: 49 PASRPPALS--------------------PLSPRAVASQWPEELASARRAAVLGRRAGPE 88
RPP S P SP A++ W AS+ + A P
Sbjct: 285 VRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAW----ASSWESEAAPEPAAPP 340
Query: 89 LLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWAT 148
P V+A P + RG+P R +RR PP+T RG +
Sbjct: 341 AAPSPPDSPAEGRLVKA-QYIPGAQAATRGLP-------GRAARRKPPPLT--RGRSVEQ 390
Query: 149 AP------ADGSRGSRPLAKGSREEVKAPRAGGSAAEDLRLPSTSFALTG 192
+P A G RG A G R +A +A S +E L S +G
Sbjct: 391 SPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSG 440
Score = 36.6 bits (83), Expect = 0.15
Identities = 49/168 (29%), Positives = 62/168 (36%), Gaps = 21/168 (12%)
Query: 7 ERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPLSPRAVAS 66
ER G P +P L W + W++ P A PA+ P SP R V +
Sbjct: 308 ERVGGHPTSPAA-----LSRAWASS-----WESEAAPEPAAPPAAPSPPDSPAEGRLVKA 357
Query: 67 QWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLG 126
Q+ +A R L RA P GR E AG RRGR A + G
Sbjct: 358 QYIPGAQAATRG--LPGRAARRKPPPLTRGRSVEQSPPRERPRAAG-RRGRMAEASGRRG 414
Query: 127 G--ARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPR 172
AR++ R+Q T G A A G REE + PR
Sbjct: 415 SPRARKASRSQSE-TSLLGRASAV-----PSGPPKYPTAEREEPRPPR 456
Score = 30.8 bits (68), Expect = 8.2
Identities = 40/116 (34%), Positives = 44/116 (37%), Gaps = 12/116 (10%)
Query: 2 EAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPLSP 61
E R RP P L W + AEI A G RP APA+R P P SP
Sbjct: 450 EEPRPPRPRRGPAPTLAAQAAGSCRRW-RSTAEID-AADGRRVRPRAPAARVPGPGP-SP 506
Query: 62 RA------VASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPA 111
A + SA R LGRR GP GGG G + G SPA
Sbjct: 507 SAPQRRLLYGCAGSDSECSAGRLGPLGRR-GP--AGGVGGGYGESESSASEGESPA 559
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 38.1 bits (87), Expect = 0.052
Identities = 50/168 (29%), Positives = 63/168 (37%), Gaps = 37/168 (22%)
Query: 5 RTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPG-RPAAPASRPPALSPLSPRA 63
RT G PG+P G S AG E + PG RPA PA PA SP
Sbjct: 507 RTGPKEGTPGSPSETPGP---SPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP----- 558
Query: 64 VASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPA 123
S+ P R AGP G E E G SPAG R +P+
Sbjct: 559 --SETPGP-----------RPAGP------AGDEPAESPSETPGPSPAGPTRDEPAESPS 599
Query: 124 KLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAP 171
+ G R + A GD A +P++ + G RP E ++P
Sbjct: 600 ETPGPRPAGPA--------GDEPAESPSE-TPGPRPAGPAGDEPAESP 638
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 38.1 bits (87), Expect = 0.052
Identities = 43/138 (31%), Positives = 52/138 (37%), Gaps = 12/138 (8%)
Query: 49 PASRPPALSPLSPRAVASQWPEELASARRAAVLGRRA--GPELLPQQGGGRGG----EMQ 102
PA+R P L L+PR S P + VLG G + L ++ GG GG E
Sbjct: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 103 VEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLA- 161
AG T AG P G R RA P G + A G+ PL
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASG---RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 162 KGSREEVKAPRAGGSAAE 179
KG R + A G A E
Sbjct: 132 KGLRISAEETVARGKATE 149
Score = 32.7 bits (73), Expect = 2.2
Identities = 59/234 (25%), Positives = 76/234 (32%), Gaps = 56/234 (23%)
Query: 6 TERPAG--RPGAPLVRTGLLLLSTWVLAGAEITWDATGG--------------PGRPAA- 48
T RP G RP P+ L +L G + + GG P R A
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 49 ----PASRPPA---------LSPLSPRAVASQWPEELASARRAAVLGRRA---------- 85
PASRPPA SP V+S P + R LG++
Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 86 ------GPELLPQQGGGRGGEMQVEAGGTSPAGERRGR------GIPAPAKLGGARRSRR 133
P+ G R G SPA RR R G+P PA R
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 134 AQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAEDLRLPSTS 187
+ T P+ +R RP A G + A R+ S+A L P+ S
Sbjct: 204 GPRKSVSSASEHSTTEPSPAAR-RRPSAGGGLQR-PASRSLSSSATPLSSPARS 255
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 38.1 bits (87), Expect = 0.052
Identities = 43/138 (31%), Positives = 52/138 (37%), Gaps = 12/138 (8%)
Query: 49 PASRPPALSPLSPRAVASQWPEELASARRAAVLGRRA--GPELLPQQGGGRGG----EMQ 102
PA+R P L L+PR S P + VLG G + L ++ GG GG E
Sbjct: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 103 VEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLA- 161
AG T AG P G R RA P G + A G+ PL
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASG---RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 162 KGSREEVKAPRAGGSAAE 179
KG R + A G A E
Sbjct: 132 KGLRISAEETVARGKATE 149
Score = 32.7 bits (73), Expect = 2.2
Identities = 59/234 (25%), Positives = 76/234 (32%), Gaps = 56/234 (23%)
Query: 6 TERPAG--RPGAPLVRTGLLLLSTWVLAGAEITWDATGG--------------PGRPAA- 48
T RP G RP P+ L +L G + + GG P R A
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 49 ----PASRPPA---------LSPLSPRAVASQWPEELASARRAAVLGRRA---------- 85
PASRPPA SP V+S P + R LG++
Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 86 ------GPELLPQQGGGRGGEMQVEAGGTSPAGERRGR------GIPAPAKLGGARRSRR 133
P+ G R G SPA RR R G+P PA R
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 134 AQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAEDLRLPSTS 187
+ T P+ +R RP A G + A R+ S+A L P+ S
Sbjct: 204 GPRKSVSSASEHSTTEPSPAAR-RRPSAGGGLQR-PASRSLSSSATPLSSPARS 255
>gi|194272140 dendrin [Homo sapiens]
Length = 711
Score = 38.1 bits (87), Expect = 0.052
Identities = 38/129 (29%), Positives = 49/129 (37%), Gaps = 25/129 (19%)
Query: 83 RRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGR--GIPA------------------- 121
R + LL Q GGGRGGE + G S ER R G+PA
Sbjct: 513 RLSSSRLLHQPGGGRGGEAEGGRPGDSTLEERTFRILGLPAPEVNLRDAPTQPGSPEHQA 572
Query: 122 --PAKLGGARRSRRAQPPITQER-GDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAA 178
PA G R+ ++ + Q R G WA P + R R AP + A
Sbjct: 573 LGPAASGAQGRAEGSEVAVVQRRAGRGWARTPGPYAGALREAVSRIRRHT-APDSDTDEA 631
Query: 179 EDLRLPSTS 187
E+L + S S
Sbjct: 632 EELSVHSGS 640
Score = 31.2 bits (69), Expect = 6.3
Identities = 50/206 (24%), Positives = 66/206 (32%), Gaps = 59/206 (28%)
Query: 43 PGRPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQ--------- 93
PGRP P ++ L+ + PE LA +GR P PQ
Sbjct: 140 PGRPRPEPRNAPRVAQLAGLPAPLR-PERLAP------VGRAPRPSAQPQSDPGSAWAGP 192
Query: 94 -GGGRGGEMQVEA-------GGTSPA----------------------GERRGRG----- 118
GG R G EA GT+P G +RG G
Sbjct: 193 WGGRRPGPPSYEAHLLLRGSAGTAPRRRWDRPPPYVAPPSYEGPHRTLGTKRGPGNSQVP 252
Query: 119 ---IPA--PAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRA 173
PA PA+ G R +R P I ++ AW G G P +R P
Sbjct: 253 TSSAPAATPARTDGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARAR---PEP 309
Query: 174 GGSAAEDLRLPSTSFALTGDSAHNQA 199
G E + + +G +H QA
Sbjct: 310 GKGVVEKSLGLAAADLNSGSDSHPQA 335
>gi|239748460 PREDICTED: hypothetical protein [Homo sapiens]
Length = 272
Score = 37.7 bits (86), Expect = 0.067
Identities = 36/101 (35%), Positives = 46/101 (45%), Gaps = 10/101 (9%)
Query: 43 PGRPAAPASRPPALSPL-------SPRAVASQWPE-ELASARRAAVLGRRAGPELLPQQG 94
PGRPA+ + PPA S L SP +++ P+ + S R AVL R P P
Sbjct: 107 PGRPASAS--PPAASRLPAAAKTTSPAVLSAVGPKAKTNSGLRGAVLSRAPPPAPCPSGA 164
Query: 95 GGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQ 135
RGGE + G RRG A A L +R S RA+
Sbjct: 165 LQRGGETKGRVFLFGFLGSRRGECAGAQAPLHLSRPSVRAR 205
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,188,847
Number of Sequences: 37866
Number of extensions: 2359442
Number of successful extensions: 8844
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 287
Number of HSP's that attempted gapping in prelim test: 8393
Number of HSP's gapped (non-prelim): 691
length of query: 1222
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1108
effective length of database: 13,930,794
effective search space: 15435319752
effective search space used: 15435319752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.