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Search of human proteins with 18375676
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18375676 UPF2 regulator of nonsense transcripts homolog
[Homo sapiens]
(1272 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 2559 0.0
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 2559 0.0
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 79 3e-14
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 77 1e-13
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 75 5e-13
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 74 7e-13
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 74 9e-13
gi|148746195 trichohyalin [Homo sapiens] 73 2e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 72 3e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 72 3e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 71 8e-12
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 70 1e-11
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 70 1e-11
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 70 1e-11
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 70 1e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 70 2e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 69 4e-11
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 69 4e-11
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 69 4e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 67 8e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 67 1e-10
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 67 1e-10
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 67 1e-10
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 67 1e-10
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 67 1e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 66 2e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 65 3e-10
gi|221219020 NYD-SP11 protein [Homo sapiens] 65 3e-10
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 65 3e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 65 5e-10
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 2559 bits (6632), Expect = 0.0
Identities = 1272/1272 (100%), Positives = 1272/1272 (100%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL
Sbjct: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ
Sbjct: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
Query: 121 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT
Sbjct: 121 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
Query: 181 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 240
ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL
Sbjct: 181 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 240
Query: 241 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 300
LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE
Sbjct: 241 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 300
Query: 301 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 360
SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF
Sbjct: 301 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 360
Query: 361 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 420
TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL
Sbjct: 361 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 420
Query: 421 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 480
DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA
Sbjct: 421 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 480
Query: 481 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 540
ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA
Sbjct: 481 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 540
Query: 541 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 600
EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN
Sbjct: 541 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 600
Query: 601 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 660
RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI
Sbjct: 601 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 660
Query: 661 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 720
ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES
Sbjct: 661 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 720
Query: 721 HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 780
HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY
Sbjct: 721 HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 780
Query: 781 KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 840
KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED
Sbjct: 781 KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 840
Query: 841 VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 900
VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG
Sbjct: 841 VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 900
Query: 901 VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 960
VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE
Sbjct: 901 VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 960
Query: 961 VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 1020
VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK
Sbjct: 961 VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 1020
Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT
Sbjct: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
Query: 1081 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1140
DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV
Sbjct: 1081 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1140
Query: 1141 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1200
AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN
Sbjct: 1141 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1200
Query: 1201 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1260
QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN
Sbjct: 1201 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1260
Query: 1261 ADLIFKTGGRRR 1272
ADLIFKTGGRRR
Sbjct: 1261 ADLIFKTGGRRR 1272
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 2559 bits (6632), Expect = 0.0
Identities = 1272/1272 (100%), Positives = 1272/1272 (100%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL
Sbjct: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ
Sbjct: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
Query: 121 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT
Sbjct: 121 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
Query: 181 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 240
ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL
Sbjct: 181 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 240
Query: 241 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 300
LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE
Sbjct: 241 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 300
Query: 301 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 360
SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF
Sbjct: 301 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 360
Query: 361 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 420
TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL
Sbjct: 361 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 420
Query: 421 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 480
DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA
Sbjct: 421 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 480
Query: 481 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 540
ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA
Sbjct: 481 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 540
Query: 541 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 600
EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN
Sbjct: 541 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 600
Query: 601 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 660
RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI
Sbjct: 601 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 660
Query: 661 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 720
ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES
Sbjct: 661 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 720
Query: 721 HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 780
HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY
Sbjct: 721 HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 780
Query: 781 KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 840
KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED
Sbjct: 781 KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 840
Query: 841 VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 900
VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG
Sbjct: 841 VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 900
Query: 901 VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 960
VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE
Sbjct: 901 VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 960
Query: 961 VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 1020
VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK
Sbjct: 961 VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 1020
Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT
Sbjct: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
Query: 1081 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1140
DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV
Sbjct: 1081 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1140
Query: 1141 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1200
AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN
Sbjct: 1141 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1200
Query: 1201 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1260
QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN
Sbjct: 1201 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1260
Query: 1261 ADLIFKTGGRRR 1272
ADLIFKTGGRRR
Sbjct: 1261 ADLIFKTGGRRR 1272
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 79.0 bits (193), Expect = 3e-14
Identities = 44/168 (26%), Positives = 90/168 (53%), Gaps = 6/168 (3%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+RKK +E++ +EK ERR ++R K+ K K+ + + KK+R E +
Sbjct: 65 KRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE 124
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
+ K+ +ERK+K K K +E K+++E K++ + ++RKK+E + KR++ + + +E
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERE 184
Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKN 171
++E + +E +KE R K + D + + S++ L+++
Sbjct: 185 RKERRERKKER------KKERRKKKERKKDRKTDRQTDSQVFRPLRES 226
Score = 74.7 bits (182), Expect = 5e-13
Identities = 49/215 (22%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 7 KPASMEEKDSLPNNKEKDCS--ERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
KP + E + +E++ ER +ER K + K K+E K E K+K E +
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 65 RKKEDKERKKKDEEKVKAEEESK-----KKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
+++ +KER+K+ +EK K E + + KK++E K++ +E +++++ ++ KR++++
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Query: 120 QMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLK 179
+ +EKE + + + R++ R +N+ E KK K+ K
Sbjct: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Query: 180 TITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKL 214
+ R + S F L S + V + ++
Sbjct: 207 KDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRI 241
Score = 66.6 bits (161), Expect = 1e-10
Identities = 36/167 (21%), Positives = 91/167 (54%), Gaps = 2/167 (1%)
Query: 4 ERKKPASMEEKDSLPNNKE-KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
ERK+ +EK + K+ +R K+R + K K++ K ++K+R
Sbjct: 53 ERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRR 112
Query: 63 DKRKKED-KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQM 121
+++KK++ KER+++++++ + + + ++K++ K++ +E+ER K+E + K++++EE +
Sbjct: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
+ + + +E ER +KE + + + + + + + DS +
Sbjct: 173 ERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
Score = 62.0 bits (149), Expect = 3e-09
Identities = 31/137 (22%), Positives = 79/137 (57%), Gaps = 4/137 (2%)
Query: 26 SERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEK----VK 81
+E + VS K + ++++ + +K+KR + +RK+E +++KK +K +
Sbjct: 15 TELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKE 74
Query: 82 AEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLR 141
E + K++E++ K++ ++E RK+++E+ KR++++ + K+K+E + +E +R +
Sbjct: 75 RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK 134
Query: 142 KELRSKNQNAPDSRPEE 158
++ R K + + + E+
Sbjct: 135 RKKRRKKKRRKERKREK 151
Score = 59.7 bits (143), Expect = 2e-08
Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 15/147 (10%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
K+ EK+ KEK ER+ +ER K + ++E + E K+K+ KR
Sbjct: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR 143
Query: 66 KKEDK-------------ERKKKDEEKVKAEEESKKKEEEEKKKHQE--EERKKQEEQAK 110
+KE K +RKK++ EK + ++K+E E+K+ +E +ERKK+ + K
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Query: 111 RQQEEEAAAQMKEKEESIQLHQEAWER 137
++++ + + + L + A+ R
Sbjct: 204 ERKKDRKTDRQTDSQVFRPLRESAFNR 230
Score = 50.4 bits (119), Expect = 1e-05
Identities = 36/147 (24%), Positives = 75/147 (51%), Gaps = 9/147 (6%)
Query: 29 RTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
+ +SS+ K + +L + VS + K + +RKKE +ER+K+ E+ K E + ++
Sbjct: 3 KAISSRAAVKLNTEL---QMVSCSHISKPCTQRESERKKERREREKRKREREK-ERKRER 58
Query: 89 KEEEEKKKH-----QEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKE 143
++E+KK+ +E ERK++E + +R++ E + ++KE+ + ++ R +K+
Sbjct: 59 GKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK 118
Query: 144 LRSKNQNAPDSRPEENFFSRLDSSLKK 170
R + + R E R +K
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRK 145
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/120 (23%), Positives = 63/120 (52%), Gaps = 11/120 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
ERKK +E++ NK++ +R+ K+R K+ + +KE K +KKR +++
Sbjct: 113 ERKKKKERKERER--ENKQRRERKRKKRRKKKRRKERKR---EKERGKRERKRKKRKKEE 167
Query: 64 KRKKEDKER------KKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
+ KK ++ R +++ E + + +E K++ +++++K + ++ + Q R E A
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 77.0 bits (188), Expect = 1e-13
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E KK E K +EK ER +ER K + K KKE E KK+R E +
Sbjct: 50 EGKKERESERKKER-REREKRKREREKERKRERGKKEKKGERKKEER---ERKKRRREKE 105
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
++ E+KE++KK E+K + + KE E K++ + EERK++E + + +++E + K+
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKK 165
Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITE 183
+E +E + RKE + + +N + + E R + ++ KK + E
Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK----KKEERKKE 221
Query: 184 QQRD 187
+Q+D
Sbjct: 222 RQKD 225
Score = 73.9 bits (180), Expect = 9e-13
Identities = 43/154 (27%), Positives = 87/154 (56%), Gaps = 7/154 (4%)
Query: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDI--KLTAKKEVSKAPEDKKKRL 60
+ERKK EK KE+ + ER K++ K +++ +K E+K+KR
Sbjct: 57 SERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116
Query: 61 EDDKRK-----KEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115
+ +K++ KE KER++K+E K + +E ++K+EE +K+ + +ERKK+E + ++EE
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEE 176
Query: 116 EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
E + +++ + + +++ ++ RKE R + +
Sbjct: 177 ERKEKERKERKKRERNRKERKKERERKERRERKK 210
Score = 71.2 bits (173), Expect = 6e-12
Identities = 34/113 (30%), Positives = 68/113 (60%), Gaps = 2/113 (1%)
Query: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105
++E+ E KK+R + K+++ ++E++K++ EK + E KK+++ E+KK + E +K++
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
E+ ++ EE+ + KEK+E + +E ER RKE R + + R +E
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERE--RKEERKREERKERERKKE 152
Score = 68.9 bits (167), Expect = 3e-11
Identities = 39/141 (27%), Positives = 77/141 (54%), Gaps = 5/141 (3%)
Query: 23 KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA 82
K C++ S + +I+ + + + E KK+R E +KRK+E ++ +K++ K +
Sbjct: 27 KPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
Query: 83 EEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-----AAAQMKEKEESIQLHQEAWER 137
+ E KK+E E KK+ +E+E K+ EE+ KR+++E+ + + KE+E + +E +
Sbjct: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
Query: 138 HHLRKELRSKNQNAPDSRPEE 158
+KE R K + + + E
Sbjct: 147 RERKKEEREKERERKERKKRE 167
Score = 67.0 bits (162), Expect = 1e-10
Identities = 44/150 (29%), Positives = 85/150 (56%), Gaps = 8/150 (5%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+R++ +E + K+K+ ER +SKE + + K K+E K E KK E+
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGR-TSKEGKERERKEERKREERKERERKK---EER 154
Query: 64 KRKKEDKERKKKDEEKV-KAEEESKKKEEEEKKKHQ---EEERKKQEEQAKRQQEEEAAA 119
++++E KERKK++ ++V + EEE K+KE +E+KK + +E +K++E + +R++++E
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 120 QMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
+ + K+E + Q W K R + +
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 35.0 bits (79), Expect = 0.46
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 1025 EGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNK 1084
+GE +E+ E ++ E E + G E E + +E++ EG+E E + + + K
Sbjct: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE-ERKREERK 145
Query: 1085 ENETDEENTE 1094
E E +E E
Sbjct: 146 ERERKKEERE 155
Score = 32.0 bits (71), Expect = 3.9
Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Query: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
+K++K+ E E ++ E++E G E + E + EE + + +E E+E E
Sbjct: 103 EKENKEG-EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161
Query: 1076 TDYLTDSNKENETDEENTE 1094
+ + E +EE E
Sbjct: 162 ERKKRERKQVGEKEEERKE 180
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 74.7 bits (182), Expect = 5e-13
Identities = 36/123 (29%), Positives = 78/123 (63%), Gaps = 3/123 (2%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
+KK +E + +E + E + KE+ K+ K KK+ +K E +K++ E++K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
++K +++KK++EE+ + EEE ++++EEE+K EE R++++++ +R++EEE + K +
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEK---EEGRRRKKKKKRRRKEEEEEKKKKRR 117
Query: 125 EES 127
++
Sbjct: 118 RKT 120
Score = 72.8 bits (177), Expect = 2e-12
Identities = 37/110 (33%), Positives = 72/110 (65%), Gaps = 5/110 (4%)
Query: 34 KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEE 93
K++ K + + T + E ++ E+K + KRK++ KE++K+ E+K K +E K+KE+EE
Sbjct: 3 KKKKKKETEETEETEETEEEEEK-----EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57
Query: 94 KKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKE 143
++K ++ +RKK++E+ +R++EEE + KE+EE + + ++ RKE
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107
Score = 70.9 bits (172), Expect = 8e-12
Identities = 37/118 (31%), Positives = 74/118 (62%), Gaps = 4/118 (3%)
Query: 34 KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA-EEESKKKEEE 92
K++ ++ + T + E + E K+K +KRK+++K++K K+ EK K EEE KK++ +
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65
Query: 93 EKKKHQEEERKKQEEQA---KRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSK 147
KKK +EEER+++EE+ K ++E+E + K+K++ + +E ++ R++ + K
Sbjct: 66 RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 69.7 bits (169), Expect = 2e-11
Identities = 33/113 (29%), Positives = 71/113 (62%)
Query: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ 105
KK+ K E+ ++ E ++ ++++ +RK+K +EK K +E+ KK +E EK+K +EEE KK+
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
+ + K+++EEE + +E+EE + +E E +K+ + + + + + ++
Sbjct: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Score = 60.5 bits (145), Expect = 1e-08
Identities = 36/120 (30%), Positives = 70/120 (58%), Gaps = 11/120 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE---DKKKRL 60
++KK + E +++ +E++ +R KE+ K+ K KE K E ++KKR
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 61 EDDKRKKEDKERKK----KDEEKVKAEEES----KKKEEEEKKKHQEEERKKQEEQAKRQ 112
K+KKE++ER++ ++EEK + E+E KKK++ +K+ +EE++KK+ + K++
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 52.8 bits (125), Expect = 2e-06
Identities = 33/113 (29%), Positives = 64/113 (56%), Gaps = 14/113 (12%)
Query: 56 KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEE-EEKKKHQEEERK---------KQ 105
KKK+ K+KKE +E ++ +E + + E+E K+KE+ +EK+K +E+++K K+
Sbjct: 1 KKKK----KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKE 56
Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
EE+ KR+++ + + +E+EE + +E E + R K + + EE
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109
Score = 48.5 bits (114), Expect = 4e-05
Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 9/118 (7%)
Query: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129
K++KKK E + E E ++EEE++ K +E+ ++K++E+ K+++ +E + KEKEE
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKE-TEKRKEKEEE-- 58
Query: 130 LHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRD 187
E+ RK + K + + EE + + ++ KK K +++ +
Sbjct: 59 ------EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 39.7 bits (91), Expect = 0.019
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 5/76 (6%)
Query: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
+K+ K E E +E EEEE+ ++ E E E EEEE ++E EEEE+E
Sbjct: 39 EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEE-----EEEKEEEEKEE 93
Query: 1076 TDYLTDSNKENETDEE 1091
K +EE
Sbjct: 94 GRRRKKKKKRRRKEEE 109
Score = 38.1 bits (87), Expect = 0.054
Identities = 23/78 (29%), Positives = 35/78 (44%)
Query: 1017 KDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENT 1076
K K E E EE EEEEE + +E+ + + E +++ E EEEE++
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 1077 DYLTDSNKENETDEENTE 1094
+E E +EE E
Sbjct: 64 RKRKKKKEEEEREEEEEE 81
Score = 35.8 bits (81), Expect = 0.27
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
Query: 984 RPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETE 1043
+ K K EE+ ++ E+E K + K+ + + E+ +E+EE E
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEE-----E 58
Query: 1044 EQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTD 1077
E+ + EEEE + +++E EE+EEE +
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92
Score = 34.3 bits (77), Expect = 0.78
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 24/94 (25%)
Query: 1017 KDSKDSMTEGENLEEDEEEEEGG-------------------AETEEQSGNESEVNEPEE 1057
K K++ E E +EEEE+ G ETE++ E E + +
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64
Query: 1058 EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEE 1091
+ +++E EEEEEE + KE E EE
Sbjct: 65 KRKKKKEEEEREEEEEEE-----EEEKEEEEKEE 93
Score = 33.9 bits (76), Expect = 1.0
Identities = 18/74 (24%), Positives = 40/74 (54%)
Query: 484 KDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDL 543
K+ E++ + +E+ +++ KE K ++ KE + + + + E + E E + +
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK 67
Query: 544 TKKLLDEQEQEDEE 557
KK +E+E+E+EE
Sbjct: 68 KKKEEEEREEEEEE 81
Score = 33.1 bits (74), Expect = 1.7
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 1017 KDSKDSMTEGENLEE-DEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
K K E E EE +E EEE E + + + + E E+++ + + E+EEEE
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 1076 TDYLTDSNKENETDEENTE 1094
K+ E + E E
Sbjct: 61 KRKRKRKKKKEEEEREEEE 79
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 484 KDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDL 543
++ EK + KE K+ KE ++ K+ KE + E E + + + E E E+
Sbjct: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80
Query: 544 TKKLLDEQEQEDEEASTGSHLK 565
+E+E+E+EE G K
Sbjct: 81 E----EEEEKEEEEKEEGRRRK 98
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 74.3 bits (181), Expect = 7e-13
Identities = 44/160 (27%), Positives = 91/160 (56%), Gaps = 3/160 (1%)
Query: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
AE+++ A ++++ EK+ +R +R ++ +L ++E K E++K++ E+
Sbjct: 405 AEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEE 464
Query: 63 DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
K+++ +++RK +E K KAEEE KE++E++K ++ +KQ+E A+ + E A
Sbjct: 465 KKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRL 524
Query: 123 EKEE-SIQLHQEAWERHHLRKEL--RSKNQNAPDSRPEEN 159
E+E+ +Q+ QE ER E+ R++ + P +E+
Sbjct: 525 EREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKED 564
Score = 67.4 bits (163), Expect = 8e-11
Identities = 37/126 (29%), Positives = 75/126 (59%), Gaps = 5/126 (3%)
Query: 23 KDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA 82
K +E+R + ++ +++ + K+E + ++ KR +++R + ++E +K++EE+ +
Sbjct: 402 KILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQ 461
Query: 83 EEESKKKEEEEKKKHQEEERKKQEE-----QAKRQQEEEAAAQMKEKEESIQLHQEAWER 137
EEE KK+E EEK+K EE ++K EE + + Q+++E A K+KE + +E E+
Sbjct: 462 EEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQ 521
Query: 138 HHLRKE 143
L +E
Sbjct: 522 MRLERE 527
Score = 63.5 bits (153), Expect = 1e-09
Identities = 43/135 (31%), Positives = 78/135 (57%), Gaps = 10/135 (7%)
Query: 18 PNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE-DDKRKKEDKERKKKD 76
P D E + +++R + ++ ++E + ++++ RLE ++ ++K ++ER + +
Sbjct: 390 PTAGTTDAGEAAKILAEKRRQARLQ-KEQEEQERVEKEEQDRLEREELKRKAEEERLRLE 448
Query: 77 EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
EE K EEE K+ +EEEKKK + EE++K E+AKR+ EEE +KEK+E QE E
Sbjct: 449 EEARKQEEERKR-QEEEKKKQEGEEKRKAGEEAKRKAEEELL--LKEKQE-----QEKQE 500
Query: 137 RHHLRKELRSKNQNA 151
+ + K+ + A
Sbjct: 501 KAMIEKQKEAAETKA 515
Score = 46.6 bits (109), Expect = 2e-04
Identities = 33/129 (25%), Positives = 67/129 (51%), Gaps = 10/129 (7%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDC-----SERRTVSSKERPKDDIKLTAKKEVSKAPED 55
+P + +P ++ + S PN + + S+ R +KER ++ K A +E +
Sbjct: 23 LPGKIAEPGAV--RTSQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQ 80
Query: 56 KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115
K+ RL+ +K+ +E R +K EE+ + E++ + EE++K+ EE ++ E +R E
Sbjct: 81 KRARLQYEKQMEE---RWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLER 137
Query: 116 EAAAQMKEK 124
++K+K
Sbjct: 138 TQQLELKKK 146
Score = 45.1 bits (105), Expect = 4e-04
Identities = 24/78 (30%), Positives = 47/78 (60%), Gaps = 4/78 (5%)
Query: 53 PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEE----ESKKKEEEEKKKHQEEERKKQEEQ 108
P+ + L+ D+R++ KER+++ E+ + A E E +K+ + +K EE +K EEQ
Sbjct: 42 PQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQ 101
Query: 109 AKRQQEEEAAAQMKEKEE 126
+R+ ++ AA + K K++
Sbjct: 102 RQREDQKRAAVEEKRKQK 119
Score = 40.8 bits (94), Expect = 0.008
Identities = 26/143 (18%), Positives = 64/143 (44%), Gaps = 1/143 (0%)
Query: 77 EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
E++ +A + +++E+E +K +++ +++E + K ++E + K+E + QE +
Sbjct: 406 EKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEK 465
Query: 137 RHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGL 196
+ +E R + A EE K+ A ++K K E + ++ L
Sbjct: 466 KKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMR-L 524
Query: 197 NLSKYIAEAVASIVEAKLKISDV 219
+ + + +E K +I ++
Sbjct: 525 EREQIMLQIEQERLERKKRIDEI 547
Score = 40.0 bits (92), Expect = 0.014
Identities = 25/96 (26%), Positives = 54/96 (56%), Gaps = 4/96 (4%)
Query: 55 DKKKRLEDDKRKKEDK---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR 111
D+++RL ++R++ +K R+++ EK K +K+ EE+ + EE+R++ E+Q +
Sbjct: 52 DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQR-EDQKRA 110
Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSK 147
EE+ +++E+EE ++ + EL+ K
Sbjct: 111 AVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKK 146
Score = 36.2 bits (82), Expect = 0.21
Identities = 27/127 (21%), Positives = 52/127 (40%), Gaps = 17/127 (13%)
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK---------- 110
+D ++K +KE+ K+ E A++ + + EE +KH ++ ++ A
Sbjct: 327 QDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAA 386
Query: 111 -------RQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSR 163
EAA + EK +L +E E+ + KE + + + R E R
Sbjct: 387 LGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLR 446
Query: 164 LDSSLKK 170
L+ +K
Sbjct: 447 LEEEARK 453
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 73.9 bits (180), Expect = 9e-13
Identities = 52/175 (29%), Positives = 90/175 (51%), Gaps = 21/175 (12%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKK------ 57
E+ K ++EK+ L K+ ++ + E K+T V A E+K
Sbjct: 246 EKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAA 305
Query: 58 -------KRLEDDKRKKEDKERKKKDEEK------VKAEEES--KKKEEEEKKKHQEEER 102
K+ +D K+KK +KE K+K+++K VKA +E+ K KEEEE++K +EEER
Sbjct: 306 EDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365
Query: 103 KKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPE 157
K+ E+ + +++EE + +++E Q +E ER +L +K+Q +R E
Sbjct: 366 IKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE 420
Score = 54.7 bits (130), Expect = 6e-07
Identities = 34/128 (26%), Positives = 72/128 (56%), Gaps = 9/128 (7%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERR---TVSSKERPKDDIKLTAKKEVS-----KAPED 55
E+ + + E D+ + K+KD +++ KE+ K K T K K E+
Sbjct: 297 EKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEE 356
Query: 56 KKKRLEDDKRKK-EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
++KR E+++ K+ E+ E K+K+EE+++ E+ +KK++E+++K + ++ K +++R+
Sbjct: 357 RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREAR 416
Query: 115 EEAAAQMK 122
A A +K
Sbjct: 417 ARAEATLK 424
Score = 51.6 bits (122), Expect = 5e-06
Identities = 45/187 (24%), Positives = 86/187 (45%), Gaps = 12/187 (6%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPED-----KKKRLEDDKR 65
++E+ + ++ E + S++ K + K + ED K K + K
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKA 233
Query: 66 KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQ----EEERKKQEEQAKRQQEEEAAA-- 119
+K+++ERKK+DEEK K + +K+E E KK Q E +RK +EE K + +
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIP 293
Query: 120 QMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLK 179
+EK E+ ++ E +K+ + K + + + +E +++K + KLK
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKD-KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK 352
Query: 180 TITEQQR 186
E+Q+
Sbjct: 353 EEEERQK 359
Score = 51.2 bits (121), Expect = 6e-06
Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 18/211 (8%)
Query: 4 ERKKPASMEEKDSLPNNKEKDC------SERRTVSSKERPKDDIKLTAKKEVSKAPEDKK 57
+ KK +E D L +E ++R TV+ K ++ + T+K + K + KK
Sbjct: 46 KEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKK 105
Query: 58 KRLED-DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR----Q 112
+ +D D + EDK+ K K K K E S ++++ K ++ + K ++ K+ +
Sbjct: 106 QSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSE 165
Query: 113 QEEEAAAQMKEK---EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
++E+ + ++KE+ S + E+ E RK + +N P E D+S K
Sbjct: 166 EDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDD-DASFK 224
Query: 170 KNTAFVKKLKTITEQQRDSLSHDFNGLNLSK 200
T KK + +++R+ D L K
Sbjct: 225 IKTVAQKKAE---KKERERKKRDEEKAKLRK 252
Score = 47.4 bits (111), Expect = 9e-05
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 57/225 (25%)
Query: 14 KDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR-----KKE 68
K N K K + + + IK A+K+ K ++KKR E+ + +KE
Sbjct: 198 KGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKE 257
Query: 69 DKERKKKDEEKVKAEEESKKKEEEEKKK--------------------------HQEEER 102
+ E KKD+ K K ES++K EEE K ++ +++
Sbjct: 258 ELETGKKDQSKQK---ESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314
Query: 103 KKQEEQAKRQQEE------------------EAAAQMKEKEESIQLHQEAWERHHLRKEL 144
KK +++ K ++EE EA A++KE+EE + +E ER +EL
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE--ERIKRLEEL 372
Query: 145 RSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL-KTITEQQRDS 188
+K + + R E+ R K+ +KK K +T+ QR++
Sbjct: 373 EAKRKE--EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREA 415
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/121 (24%), Positives = 62/121 (51%), Gaps = 4/121 (3%)
Query: 52 APEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR 111
A +++ +++E +K E KE +++EE+ + EEE ++ EEEE+++ + E + EE K
Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569
Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKN 171
E+++ + +K + + + + + R+K + A D RL+ S N
Sbjct: 570 SDEKDSGKTLDKKPSK----EMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVN 625
Query: 172 T 172
T
Sbjct: 626 T 626
Score = 45.1 bits (105), Expect = 4e-04
Identities = 33/129 (25%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
+ +K S E++D+ KE+ R S + + D L ++K K ++K +
Sbjct: 157 SNKKWDGSEEDEDNSKKIKERS---RINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIE 213
Query: 63 DKRKKEDKERKKKDEEKVKAEEES--KKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
+ +D K K + KAE++ +KK +EEK K ++ + K++ E K+ Q ++ +Q
Sbjct: 214 SGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQ 273
Query: 121 MKEKEESIQ 129
K +EE+++
Sbjct: 274 RKFEEETVK 282
Score = 44.7 bits (104), Expect = 6e-04
Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 13/166 (7%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK--KKR-- 59
ERKK E K+ L KE + ++ R + +KL + V +D KKR
Sbjct: 388 ERKKQKEKERKERL--KKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPI 445
Query: 60 LEDDKRKKEDKERKKKDEEK-------VKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ 112
ED KRKK ++ + K+ + V+ E+ ++EE + EE + E+
Sbjct: 446 YEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDD 505
Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
E A+ + EK E ++H E E +E + + +S EE
Sbjct: 506 WEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEE 551
Score = 44.7 bits (104), Expect = 6e-04
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 21/129 (16%)
Query: 1030 EEDEEEEEGG----------AETEEQSGNESEV------NEPEEEEGSDNDDDEGEEEEE 1073
EE+E+ E+ G ETE+ GN+ + E EEEE + +D+E EEEEE
Sbjct: 493 EEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEE 552
Query: 1074 ENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVE---DEDFIQALDKMMLENLQQRSG 1130
E + ++ ++ +E DE+ ++ G L P E D ++ D+ E ++
Sbjct: 553 EEGE--SEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAK 610
Query: 1131 ESVKVHQLD 1139
++ +L+
Sbjct: 611 RRIEKRRLE 619
Score = 44.7 bits (104), Expect = 6e-04
Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 5/67 (7%)
Query: 1027 ENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDS--NK 1084
EN EE+EEEEE E EE +E E E E EGS+ D+++ + +E+++ D +K
Sbjct: 529 ENPEEEEEEEE---EEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK 585
Query: 1085 ENETDEE 1091
E +D E
Sbjct: 586 EMSSDSE 592
Score = 44.3 bits (103), Expect = 8e-04
Identities = 44/188 (23%), Positives = 79/188 (42%), Gaps = 18/188 (9%)
Query: 31 VSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKE 90
V KE ++ +++ A D + + D+ ++ + K E K EEE +++E
Sbjct: 480 VPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEE 539
Query: 91 EEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQN 150
EEE+ + EEE +++ E + +EE EK+ L ++ KE+ S ++
Sbjct: 540 EEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP------SKEMSSDSEY 593
Query: 151 APDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIV 210
D D K+ A+ K + I E++R S + N L I + +
Sbjct: 594 DSD-----------DDRTKEERAYDKAKRRI-EKRRLEHSKNVNTEKLRAPIICVLGHVD 641
Query: 211 EAKLKISD 218
K KI D
Sbjct: 642 TGKTKILD 649
Score = 44.3 bits (103), Expect = 8e-04
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Query: 1016 DKDSKDS-MTEGENLEEDEEEE--EGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEE 1072
++D++D+ + + E + DEE E EG E N E E EEEE D + +E EEEE
Sbjct: 495 EEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEE 554
Query: 1073 EENTDYLTDSNKENETDEENT 1093
E+ D E +DE+++
Sbjct: 555 GESEGSEGDEEDEKVSDEKDS 575
Score = 44.3 bits (103), Expect = 8e-04
Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Query: 1020 KDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYL 1079
K++ E E EE+EEE+E E EE+ G ESE +E +EE+ +D+ + + ++
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEEG-ESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE 586
Query: 1080 TDSNKENETDEENTE 1094
S+ E ++D++ T+
Sbjct: 587 MSSDSEYDSDDDRTK 601
Score = 41.6 bits (96), Expect = 0.005
Identities = 21/70 (30%), Positives = 37/70 (52%)
Query: 1025 EGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNK 1084
E E EE+EE+EE E EE+ +E + E+E+ SD D +++ + + +DS
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEY 593
Query: 1085 ENETDEENTE 1094
+++ D E
Sbjct: 594 DSDDDRTKEE 603
Score = 41.2 bits (95), Expect = 0.006
Identities = 20/73 (27%), Positives = 38/73 (52%)
Query: 1015 NDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEE 1074
N ++ ++ E E EE EEEEE E+E G+E + +E++ D + +E
Sbjct: 530 NPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS 589
Query: 1075 NTDYLTDSNKENE 1087
+++Y +D ++ E
Sbjct: 590 DSEYDSDDDRTKE 602
Score = 40.4 bits (93), Expect = 0.011
Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 14/93 (15%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLE---------EDEEEEEGGAETEE 1044
EE+ V+ E E GL +D ++ S E E +E E+ EEEE E EE
Sbjct: 484 EETPPPVEPEEEEDTEDAGL-DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEE 542
Query: 1045 QSGNESEVNEPEEEEGSDNDDDEGEEEEEENTD 1077
E E +E EEEE +++ EG+EE+E+ +D
Sbjct: 543 ----EDEESEEEEEEEGESEGSEGDEEDEKVSD 571
Score = 39.7 bits (91), Expect = 0.019
Identities = 37/166 (22%), Positives = 73/166 (43%), Gaps = 45/166 (27%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKE-RPK----------DDIKLTAKKEVSKA 52
++KK +K S +N ++ ++ + S K +PK DD KK KA
Sbjct: 95 DKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKA 154
Query: 53 PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEE------EKKKHQE------- 99
+ KK D + ED +K K+ ++ + ES + +E +KK+Q+
Sbjct: 155 QKSNKKW--DGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212
Query: 100 -----------------EERKKQEEQAKRQQEEEAA--AQMKEKEE 126
+++ +++E+ +++++EE A ++KEKEE
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEE 258
Score = 38.5 bits (88), Expect = 0.041
Identities = 46/232 (19%), Positives = 101/232 (43%), Gaps = 22/232 (9%)
Query: 1016 DKDSKDSMTE-GENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDD-------- 1066
DK KD + GE E+++E+++G ++ ++ E+ EEEE +++
Sbjct: 312 DKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE 371
Query: 1067 -EGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENL 1125
E + +EEE + ++ + ++E E + K G L + + +A + L+ L
Sbjct: 372 LEAKRKEEERLEQ-EKRERKKQKEKERKERLKKEGKL----LTKSQREARARAEATLKLL 426
Query: 1126 QQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKG--NKQQF 1183
Q + E L P++ + +K P + +ES + V + +G K++
Sbjct: 427 QAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEET 486
Query: 1184 KILNVPMSSQ----LAANHWNQQQAEQE-ERMRMKKLTLDINERQEQEDYQE 1230
P + + W +++E E++ K+ +++ E E+E+ +E
Sbjct: 487 PPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEE 538
Score = 36.6 bits (83), Expect = 0.16
Identities = 29/132 (21%), Positives = 58/132 (43%), Gaps = 26/132 (19%)
Query: 989 LCNSLEESIRQVQDL--EREFLIKLGLVNDKD---SKDSMTEGENLEEDEEEEEGGAETE 1043
+ LEE + Q + +RE + N+++ SKD +G+ ++ ++ E E
Sbjct: 58 ILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE 117
Query: 1044 EQSGNESEVNEPEEE--EGSDNDDD-------------------EGEEEEEENTDYLTDS 1082
++ + +P+ E GSD+DDD +G EE+E+N+ + +
Sbjct: 118 DKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKER 177
Query: 1083 NKENETDEENTE 1094
++ N + E E
Sbjct: 178 SRINSSGESGDE 189
Score = 36.2 bits (82), Expect = 0.21
Identities = 29/114 (25%), Positives = 59/114 (51%), Gaps = 20/114 (17%)
Query: 33 SKERPKDDIKLTA-KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEK------------ 79
S++ KDDI L A E+ A K++ + K KK+ KE+KK+D ++
Sbjct: 9 SEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKK-KEKKKQDFDEDDILKELEELSL 67
Query: 80 ----VKAEEE--SKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEES 127
+KA+ E + K E +++ +++KK+ ++ K+Q ++ ++ E ++S
Sbjct: 68 EAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121
Score = 35.4 bits (80), Expect = 0.35
Identities = 29/155 (18%), Positives = 72/155 (46%), Gaps = 15/155 (9%)
Query: 14 KDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERK 73
+++L KE++ ++R + + ++++ K+E E ++++ + +K +KE K
Sbjct: 345 QEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKE--RLK 402
Query: 74 KKDEEKVKAEEESKKKEEEEKKKHQEE----------ERKKQEEQAKRQQEEEAAAQMKE 123
K+ + K++ E++ + E K Q + +K+ + K++++ + KE
Sbjct: 403 KEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKE 462
Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
ES++L + + + K + P PEE
Sbjct: 463 VSESMELCAAV---EVMEQGVPEKEETPPPVEPEE 494
Score = 33.9 bits (76), Expect = 1.0
Identities = 112/653 (17%), Positives = 237/653 (36%), Gaps = 122/653 (18%)
Query: 32 SSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEE 91
++KE+ K KKE K D+ L++ + + + K D E V + +EE
Sbjct: 31 AAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEE 90
Query: 92 ----EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH---QEAWERHHLRKEL 144
++KKK Q+ +++ ++ + E++ + K + ++++ + + + L K+
Sbjct: 91 FTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKA 150
Query: 145 RSKNQNA----------PDSRPEENFFSRLDSSLK---KNTAFVKKLKTITEQQRDSLSH 191
+ K Q + D+ + SR++SS + ++ F++ K + Q++
Sbjct: 151 KGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGP 210
Query: 192 DFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEAR 251
+ N + + ++ + K + + ++ D + L+ K+ E
Sbjct: 211 NIESGNEDDDASFKIKTVAQKKAEKKE----------RERKKRDEEKAKLRKLKEKEELE 260
Query: 252 KEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRESHTHVSVVISF 311
+K + +K + R E T+ T G+ E+ A + +
Sbjct: 261 TGKK--DQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNE-------- 310
Query: 312 CRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDH 371
GD K +K E +K+ P + +K +L K + +
Sbjct: 311 ----GD----------KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEE 356
Query: 372 RE-------------LQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLAD 418
R+ L+ ++ R+ K E + + K+ +E KLL SQ A
Sbjct: 357 RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREAR 416
Query: 419 LLDE--------------NMPDLPQDKPTPE--------------------EHGPGIDIF 444
E + LP+ +P E E +++
Sbjct: 417 ARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVM 476
Query: 445 TPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNK--DDTKE 502
G P + + + +E+ L D +A +++ + E NK + KE
Sbjct: 477 EQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA-------SDEETEKVEGNKVHIEVKE 529
Query: 503 AKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQE-------QED 555
E +E +E +D E E E E + G E ++ +K+ DE++ +
Sbjct: 530 NPEEEEEEEEEEEEDEESEEEEEEEGESE-----GSEGDEEDEKVSDEKDSGKTLDKKPS 584
Query: 556 EEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRAL 608
+E S+ S D ++ + I+K ++ N+NT+ R ++ L
Sbjct: 585 KEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVL 637
Score = 32.0 bits (71), Expect = 3.9
Identities = 58/253 (22%), Positives = 94/253 (37%), Gaps = 59/253 (23%)
Query: 1011 LGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEE 1070
+G S+DS + +L+ E EG +EQ +S+ + +E++ D D+D+ +
Sbjct: 1 MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK 60
Query: 1071 EEEE--------NTDYLTDSNKENETDEEN-TEVMIKGGGLKHVPCVEDEDFIQALDKMM 1121
E EE D T + K E +EE T K G K Q+ D
Sbjct: 61 ELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKK--------QSFDDND 112
Query: 1122 LENLQQRSGESVKVHQLDV-------------AIPLHLKSQLRKGPPLGGGEGE------ 1162
E L+ + +S K + V +P K + +K G E
Sbjct: 113 SEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSK 172
Query: 1163 -----------AESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN----------Q 1201
ES D + +RKG K+ K N P + + N + Q
Sbjct: 173 KIKERSRINSSGESGDESDEFLQSRKGQKKNQK--NKPGPNIESGNEDDDASFKIKTVAQ 230
Query: 1202 QQAEQEERMRMKK 1214
++AE++ER R K+
Sbjct: 231 KKAEKKERERKKR 243
Score = 31.6 bits (70), Expect = 5.1
Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Query: 56 KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115
+K + ED + D + + E A +E + ++ + KKK +++++ E+ ++ EE
Sbjct: 5 QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE 64
Query: 116 ---EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
EA ++E E E K+ + K Q ++N L+ K+
Sbjct: 65 LSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSK 124
Query: 173 AFVK-KLKTITEQQRDSLSHDFNGL 196
K K++ + D DFN L
Sbjct: 125 KTAKPKVEMYSGSDDDD---DFNKL 146
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 73.2 bits (178), Expect = 2e-12
Identities = 40/154 (25%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
+++ E++ L +E+ E R ++ + + K+E + E++ R E +K
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYR---KEEELQQEEEQLLREEPEK 1100
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
R+++++ER+ ++EE+++ EEE +EE EK++ QE ER+ +EE+ +Q+EE+ + EK
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160
Query: 125 EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
+L ++ E L++E + + R +E
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Score = 67.8 bits (164), Expect = 6e-11
Identities = 39/143 (27%), Positives = 79/143 (55%), Gaps = 3/143 (2%)
Query: 13 EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKER 72
+KD L +E+ E R K R ++ + ++E + E++ E + R++++ ER
Sbjct: 1022 KKDELQQEEEQLLREER---EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 73 KKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQ 132
+ + EE+++ EEE +EE EK++ QE ER+ +EE+ +Q+EE+ + +EK +L +
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 133 EAWERHHLRKELRSKNQNAPDSR 155
+ E +++E + P+ R
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKR 1161
Score = 67.8 bits (164), Expect = 6e-11
Identities = 37/129 (28%), Positives = 74/129 (57%), Gaps = 1/129 (0%)
Query: 29 RTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
R K R ++ + ++E + E++ R E +KR++++ ER+ ++EE+V+ EEE
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154
Query: 89 KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKN 148
+EE EK++ QE ER+ +EE+ +Q+EE+ + +EK + ++ E L+++ R +
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ-ERERQYREEEELQRQKRKQR 1213
Query: 149 QNAPDSRPE 157
D R +
Sbjct: 1214 YRDEDQRSD 1222
Score = 67.4 bits (163), Expect = 8e-11
Identities = 42/193 (21%), Positives = 98/193 (50%), Gaps = 21/193 (10%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKER-----------------PKDDIKLTAKKEVSKAPE 54
EE+D L ++E+ S+ + K R P +L ++++ + E
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 55 DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
++ +R E +KR+++++ER+ ++EE+++ EEE +EE EK++ QE ER+ ++++ +Q+E
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
E+ + EK QE +++ +EL+ + + E+ + +K
Sbjct: 971 EQLLGEEPEKRR----RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 175 VKKLKTITEQQRD 187
++ + + ++R+
Sbjct: 1027 QQEEEQLLREERE 1039
Score = 66.6 bits (161), Expect = 1e-10
Identities = 39/155 (25%), Positives = 83/155 (53%), Gaps = 3/155 (1%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSS---KERPKDDIKLTAKKEVSKAPEDKKKRL 60
ER+K E + +K+ E + + K R ++ K ++E + E++ R
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
E +KR++++ ER+ + +++++ EEE +EE EK++ QE ER+ +EE+ +Q+EE+ +
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 121 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSR 155
+E +L ++ + L++E + P+ R
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Score = 66.2 bits (160), Expect = 2e-10
Identities = 37/156 (23%), Positives = 88/156 (56%), Gaps = 3/156 (1%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
RK+ ++E++ +E++ R+ + R ++ ++ ++++ + +K++R E ++
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ-QEEEQLLREEREKRRRQERER 958
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
+ ++DK+ ++K+E+ + E E ++++E EKK +EEE +++EEQ R++ E+ Q E+
Sbjct: 959 QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 125 E--ESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
+ + +L QE + +E R + R EE
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054
Score = 65.5 bits (158), Expect = 3e-10
Identities = 36/181 (19%), Positives = 98/181 (54%), Gaps = 14/181 (7%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
EE++ L + ++ R +E + +L ++++ + E++++ ++++R+++++
Sbjct: 273 EEEEQLRKLERQELRRER----QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
++++ + + E +++ E++ ++ QEEER+ E+Q +R+QEEE Q +E+ ++
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERR--EQQLRREQEEERREQQLRREQQLRRE 386
Query: 132 QEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSH 191
Q+ LR+E + + + R E+ R + L++ ++L+ E++R H
Sbjct: 387 QQLRREQQLRREQQLRREQ--QLRREQQL--RREQQLRRE----QQLRREQEEERHEQKH 438
Query: 192 D 192
+
Sbjct: 439 E 439
Score = 65.1 bits (157), Expect = 4e-10
Identities = 40/140 (28%), Positives = 78/140 (55%), Gaps = 5/140 (3%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
ER+K E++ L +E+ E R K R ++ + KK+ + E++ R E +
Sbjct: 985 EREK--KYREEEELQQEEEQLLREER---EKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
KR+ +++ER+ ++EE+++ EEE EE E ++ QE ER+ ++E+ +Q+EE+ + E
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE 1099
Query: 124 KEESIQLHQEAWERHHLRKE 143
K + ++ E L++E
Sbjct: 1100 KRRRQERERQCREEEELQQE 1119
Score = 63.5 bits (153), Expect = 1e-09
Identities = 35/131 (26%), Positives = 75/131 (57%), Gaps = 3/131 (2%)
Query: 13 EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKER 72
E++ L +E+ E R K R ++ + K + + E++ E +KR+++++E+
Sbjct: 932 EEEQLQQEEEQLLREER---EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
Query: 73 KKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQ 132
K ++EE+++ EEE +EE EK++ QE ER+ +++ +Q+EE+ + +EK + +
Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
Query: 133 EAWERHHLRKE 143
+ E L++E
Sbjct: 1049 QYREEEELQQE 1059
Score = 60.8 bits (146), Expect = 8e-09
Identities = 42/192 (21%), Positives = 97/192 (50%), Gaps = 18/192 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE---DKKKRL 60
E ++ + + L +E+ + + +++ + + +L ++++ + + +++ R
Sbjct: 370 EERREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKK---KEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
E ++ + E K +++ E+++K E+E ++ K EEE ++H++E RK +Q KR QEEE
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK---QQLKRDQEEER 484
Query: 118 AAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
+ + EE + Q+ LR+E + + + EE RL L+ ++
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE---ERLQQRLRSE----QQ 537
Query: 178 LKTITEQQRDSL 189
L+ E++R+ L
Sbjct: 538 LRREQEERREQL 549
Score = 60.5 bits (145), Expect = 1e-08
Identities = 44/175 (25%), Positives = 91/175 (52%), Gaps = 22/175 (12%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E++ E+ L ++ C ER ++R + + ++++S+ D+K R E+
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE--EEQQLSRQERDRKFREEEQ 1437
Query: 64 KRKKEDKERKKKDEE---------KVKAEEESKKKEEEEKKKHQEEERK--KQEEQAKRQ 112
+ +++++ERK +EE K + EE+ ++ EE++ QE +RK ++E+Q +RQ
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497
Query: 113 Q------EEEAAAQMKEK---EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
+ E+E +Q E+ EE QLH++ +R L++E + + Q R ++
Sbjct: 1498 ERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Score = 60.1 bits (144), Expect = 1e-08
Identities = 43/185 (23%), Positives = 94/185 (50%), Gaps = 14/185 (7%)
Query: 21 KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE---RKKKDE 77
+E+ R+ + K R ++ ++ ++E + E +K LE+++ + E +E R+++ +
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 78 EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK-------EESIQL 130
K + EE+ +++ EE++ + QE +RK +EE+ RQ+ EE + +++ EE +QL
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
Query: 131 -HQEAWERHHLRKELRSKNQNAPDS---RPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
QE R ++ R++ Q A R E+ + + ++ + + I QQ+
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Query: 187 DSLSH 191
+ H
Sbjct: 1891 EEQRH 1895
Score = 59.7 bits (143), Expect = 2e-08
Identities = 42/195 (21%), Positives = 99/195 (50%), Gaps = 11/195 (5%)
Query: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
A+R+ S EEK L +E+ R+ K R ++ + +++ + E +K E+
Sbjct: 1307 AKRRDRKSQEEKQLLREEREEK-RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 63 DKRKKEDKERKKKDEEKVKAEEESKK-KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQM 121
+ R +E + ++E++++ +E +K +EE++ + QE E++ ++++ ++ +EEE
Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
Query: 122 KE-----KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSS----LKKNT 172
+E +EE Q+ ++ ER L +E + + + R EE + +++
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 173 AFVKKLKTITEQQRD 187
F+++ + + Q+RD
Sbjct: 1486 KFLEEEQQLRRQERD 1500
Score = 58.9 bits (141), Expect = 3e-08
Identities = 39/163 (23%), Positives = 82/163 (50%), Gaps = 14/163 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRK---KE 68
+E++ E++ E+R +E +D +K E++ +R E ++RK K
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKR----------EEETERHEQERRKQQLKR 478
Query: 69 DKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI 128
D+E ++++ EEE ++++E +++ + E+ +++E++ KRQ+EEE Q E+ +
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 129 QLHQEAWERHHLRKELRSK-NQNAPDSRPEENFFSRLDSSLKK 170
+ QE L++E + Q + R + R D LK+
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Score = 58.5 bits (140), Expect = 4e-08
Identities = 48/206 (23%), Positives = 107/206 (51%), Gaps = 29/206 (14%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--- 60
E ++ E ++ ++++ E+R +E + +L +++++ + E+++++L
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 61 EDDKRKKEDK--ERKKKDEEK-----VKAEEESK----KKEEEEKK----KHQEEERKKQ 105
E++KR ++++ +R K+++E+ +K EEE + K+E+EE+ K +E ER +Q
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 106 EE----QAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFF 161
EE + KR++ EE Q K E QE + LR+E + + + EE
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSE----EQEERRQQQLRREQQERREQRLKREEEE--- 665
Query: 162 SRLDSSLKKNTAFVKKLKTITEQQRD 187
RL+ LK+ ++ + + E++++
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQE 691
Score = 58.5 bits (140), Expect = 4e-08
Identities = 41/172 (23%), Positives = 84/172 (48%), Gaps = 10/172 (5%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E+++ + P ++ + E++ ++R + K ++E E+K++R E D
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE----REEKRRRQETD 1335
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK-KQEEQAKRQQEEE-----A 117
++ +E+++ ++ EE+ +E +K EE+ +HQE+ RK +EEQ R+QE E
Sbjct: 1336 RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395
Query: 118 AAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
Q++ +E QL Q+ + ++ S+ + R EE R + K
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1447
Score = 57.8 bits (138), Expect = 7e-08
Identities = 38/170 (22%), Positives = 87/170 (51%), Gaps = 9/170 (5%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
+K +++K+ +E + +RR +++ +++ +L ++E E +K+R ++ +R
Sbjct: 961 RKDKKLQQKEEQLLGEEPE--KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 66 KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK--- 122
+ K+ +++EE++ EE K++ +E +++++EEE +QEE+ +E E + +
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 123 --EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
KEE +Q +E R K R + + R EE + L++
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERER--QCREEEELQQEEEQLLRE 1126
Score = 57.4 bits (137), Expect = 9e-08
Identities = 42/181 (23%), Positives = 91/181 (50%), Gaps = 20/181 (11%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKR---- 59
E ++ E++ +++ ERR +E + + +K+ K +++++R
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 60 -LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQ---EEQAKRQQEE 115
LE+++R+++ + R E++++ E+E ++ E+ K+ +EEER +Q EQ R+++E
Sbjct: 490 KLEEEERREQQERR----EQQLRREQEERR--EQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 116 EAAAQMKEKEESIQLHQE------AWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
E Q+ ++EE +L QE E+ R +L + + R + RL+ LK
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
Query: 170 K 170
+
Sbjct: 604 R 604
Score = 57.0 bits (136), Expect = 1e-07
Identities = 37/140 (26%), Positives = 75/140 (53%), Gaps = 10/140 (7%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+R K E +D L +E ERR K ++ ++ K+E + E +++R +
Sbjct: 565 QRLKREQEERRDQLLKREE----ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 64 KRKKEDKERKK---KDEEKVKAEEESKKKEEEEKKKH---QEEERKKQEEQAKRQQEEEA 117
KR++ ++ER++ K EE+ + ++ ++E++E+++ +EEE ++ E++ KR+ EEE
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680
Query: 118 AAQMKEKEESIQLHQEAWER 137
Q +EE Q + R
Sbjct: 681 REQELAEEEQEQARERIKSR 700
Score = 56.6 bits (135), Expect = 1e-07
Identities = 39/154 (25%), Positives = 85/154 (55%), Gaps = 14/154 (9%)
Query: 22 EKDCSERRTVSSKERPKDDI-KLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKV 80
E++ E+R +E +D + K ++ + ++++RLE + K+E+ ER +++E +
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERR- 616
Query: 81 KAEEESKKKEEEEKKKHQ----EEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
E+ K++E EE+++ Q EE+ +++++Q +R+Q+E ++K +EE +L Q
Sbjct: 617 --EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674
Query: 137 RHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
H +E R + + A + +E R+ S + K
Sbjct: 675 EH---EEERREQELAEEE--QEQARERIKSRIPK 703
Score = 54.7 bits (130), Expect = 6e-07
Identities = 44/193 (22%), Positives = 91/193 (47%), Gaps = 16/193 (8%)
Query: 5 RKKPASMEEKDSLPNNKEKDCS-ERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
R + + + + L +E+D ERR ++R + + ++E +A +K E+
Sbjct: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK 1318
Query: 64 KRKKEDKERKKKDEE---KVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQ------E 114
+ +E++E K++ +E K + EE+ ++ EE+ + QE +RK +EE+ + Q+ E
Sbjct: 1319 QLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
EE + +E+E ++ ++LR R EE SR + K F
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR--KFREEEQQLSRQERDRK----F 1432
Query: 175 VKKLKTITEQQRD 187
++ + + Q+R+
Sbjct: 1433 REEEQQVRRQERE 1445
Score = 54.7 bits (130), Expect = 6e-07
Identities = 37/154 (24%), Positives = 82/154 (53%), Gaps = 19/154 (12%)
Query: 13 EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKER 72
E++ L +E+ R+ K R ++ ++ +++ ++ E +K E+++ ++E +E+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 73 KKKDEE---KVKAEEESKKKEEEEKKKHQE-------------EERKKQEEQAKRQQEEE 116
+ + ++ K + EEE + EE+E++ QE +E+ ++EEQ Q+EE+
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ 1870
Query: 117 AAAQMKE---KEESIQLHQEAWERHHLRKELRSK 147
Q +E +EE I+ Q+ +RH E++S+
Sbjct: 1871 KRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Score = 53.9 bits (128), Expect = 1e-06
Identities = 35/152 (23%), Positives = 81/152 (53%), Gaps = 6/152 (3%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKR-- 59
+ +K +E++D ++E + +ER ++ +L + K E + P++++ R
Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
Query: 60 --LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
LE ++ +E+K++++++ + +EE +K+ + + ++EE K QEE+ +RQ+E +
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 118 AAQMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
+ K E +L +E E ++ LR + Q
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Score = 53.9 bits (128), Expect = 1e-06
Identities = 24/159 (15%), Positives = 82/159 (51%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
+E++ ++ RR + R + + + ++ + E ++++L ++ ++ +++
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
+++ EE+ + ++ +++EEE +++ E++ + EQ R++++ Q +E+ ++
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410
Query: 132 QEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
Q+ LR+E + + + + +++ R + LK+
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Score = 53.5 bits (127), Expect = 1e-06
Identities = 46/202 (22%), Positives = 97/202 (48%), Gaps = 23/202 (11%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+R K E +D L +E + E+ K++ K D + ++ K E++++ ++
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQER--RKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 64 KRKKEDKERKKKDEEKVKAEEESK------------KKEEEEKK----KHQEE---ERKK 104
+ ++ +E++++ E+++K +EE + ++E+EE++ K +EE E+++
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRL 164
+E++ KR+QEE +K +EE Q Q R E R K + EE RL
Sbjct: 563 REQRLKREQEERRDQLLKREEERRQ--QRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 165 DSSLKKNTAFVKKLKTITEQQR 186
+ + LK+ +++R
Sbjct: 621 KREEPEEERRQQLLKSEEQEER 642
Score = 53.1 bits (126), Expect = 2e-06
Identities = 30/123 (24%), Positives = 76/123 (61%), Gaps = 10/123 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
EE+ L +EK R+ + + R +++++ ++ + + PE K+R ++ +R+ ++E
Sbjct: 1119 EEEQLLREEREK--RRRQELERQYREEEEVQQEEEQLLREEPE--KRRRQELERQYREEE 1174
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK-----EKEE 126
+++EE++ EE+ K+++E E++ +EEE ++Q+ + +R ++E+ + +K EKE
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK-QRYRDEDQRSDLKWQWEPEKEN 1233
Query: 127 SIQ 129
+++
Sbjct: 1234 AVR 1236
Score = 53.1 bits (126), Expect = 2e-06
Identities = 41/181 (22%), Positives = 89/181 (49%), Gaps = 15/181 (8%)
Query: 21 KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK--RKKEDKERKKKDEE 78
+E+ + R R + D K +++ + E ++K +ED++ R++E +++ +++ +
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 79 KVKAEEESKKKEEEEKKKHQEEERKK---QEEQAKRQQEEEAAAQMKEKE--ESIQLHQE 133
+ E+E +E EE++ H++E +K +E Q +RQ+ E+ ++++ E QL QE
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 134 AWERHHLRKE----LRSKNQNAPDSRPEENFFSRLD----SSLKKNTAFVKKLKTITEQQ 185
E+ R+E R + Q E F L++ ++L+ TEQ+
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 186 R 186
+
Sbjct: 1739 Q 1739
Score = 52.8 bits (125), Expect = 2e-06
Identities = 42/182 (23%), Positives = 91/182 (50%), Gaps = 11/182 (6%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
+++ E++ L +E+ E R K R ++ + ++E + E++ R E +K
Sbjct: 1104 QERERQCREEEELQQEEEQLLREER---EKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEK-KKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
R++++ ER+ ++EE+++ EEE +EE+EK + QE ER+ +EE+ ++Q+ + + ++
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRR--QERERQYREEEELQRQKRKQRYRDED 1218
Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITE 183
+ ++ W+ ++ N+ R E F DS L+ + + E
Sbjct: 1219 QRSDLK-----WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273
Query: 184 QQ 185
QQ
Sbjct: 1274 QQ 1275
Score = 52.4 bits (124), Expect = 3e-06
Identities = 33/164 (20%), Positives = 84/164 (51%), Gaps = 9/164 (5%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSE------RRTVSSKERPKDDIKLTAKKEVSKAPEDKK 57
ER + +EE+ +E+ E R+ + R + D K +++ + E+++
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 58 KRLEDDKRK---KEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
++ RK +E + R+++ E++++ + + K +EEE+ + EE++ +++E+ ++ +E
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
EE + +E+E ++ R L ++ R + Q ++ E+
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
Score = 52.0 bits (123), Expect = 4e-06
Identities = 48/205 (23%), Positives = 96/205 (46%), Gaps = 23/205 (11%)
Query: 2 PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE 61
P +R++ E++ L +E+ + R + ++R + D +L +++ + E+++ E
Sbjct: 133 PGQRRRQKRQEQERELAEGEEQSEKQER-LEQRDRQRRDEELWRQRQEWQEREERRAEEE 191
Query: 62 DDKRKKEDKERKKKDEEKVKAEE--ESKKKEEEEKKKHQEEERKK---QEEQAK------ 110
+ K + + DEE+++ E E ++K EEK++ Q ER+ QEE+ K
Sbjct: 192 QLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ-QRRERQDRVFQEEEEKEWRKRE 250
Query: 111 --------RQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFS 162
+ QEEE Q + +EE QL + ER LR+E + + Q R E+
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLRK--LERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 163 RLDSSLKKNTAFVKKLKTITEQQRD 187
+ + ++ ++ + EQQ +
Sbjct: 309 KQEEERREQQEERREQQERREQQEE 333
Score = 52.0 bits (123), Expect = 4e-06
Identities = 43/187 (22%), Positives = 94/187 (50%), Gaps = 19/187 (10%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ E++ ++ E R E+ + + +L K+E + + K+ E ++
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL--KREQEERRDWLKREEETER 466
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE--EERKKQEEQAKRQQEEEAAAQMK 122
++E ++++ K +++ + E K EEEE+++ QE E++ ++E++ +R+Q ++K
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ------RLK 520
Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTIT 182
+EE +L Q LR+E + + R EE RL+ ++ ++LK
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLL-KREEE---KRLEQERRE-----QRLKREQ 571
Query: 183 EQQRDSL 189
E++RD L
Sbjct: 572 EERRDQL 578
Score = 52.0 bits (123), Expect = 4e-06
Identities = 32/119 (26%), Positives = 66/119 (55%), Gaps = 23/119 (19%)
Query: 54 EDKKKRLEDDKRKKEDKERKKKDEEKVKAEEES----------KKKEEEEKKKHQEEERK 103
E + +R E +++++D++RK ++EE+++ E E K + EE+K + QE+ERK
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596
Query: 104 --KQEEQAKRQQEEEAAAQMKEKE-----------ESIQLHQEAWERHHLRKELRSKNQ 149
+ E+Q +RQ+ ++ Q ++++ E QLH++ +R L +E + + Q
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
Score = 52.0 bits (123), Expect = 4e-06
Identities = 44/181 (24%), Positives = 95/181 (52%), Gaps = 12/181 (6%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE-DKKKRLEDDKRKKED 69
+EE+ L +E++ R K R ++ + +++ + E D+K R E+ + ++++
Sbjct: 1646 LEEEPQL-RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 70 KERKKKDEEKV--KAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEES 127
+ERK EE+ + E E K +EEE+ ++ E+E+ +++E+ ++ EEE Q++ + E
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE---QLRPEREE 1761
Query: 128 IQLHQEAWERHHLRKE-LRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
QL ++ +R +E LR + + E + R + L++ ++ + + QQR
Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE----REEQQLRPQQR 1817
Query: 187 D 187
D
Sbjct: 1818 D 1818
Score = 51.6 bits (122), Expect = 5e-06
Identities = 44/198 (22%), Positives = 99/198 (50%), Gaps = 18/198 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E ++ K L ++E++ ER +E ++ + ++E E +++R +
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE---RREQQLRREQEERREQRL 519
Query: 64 KRKKEDK--ERKKKDEEKVKAEEESKK----KEEEEKKKHQEEE----RKKQEEQ----A 109
KR++E++ +++ + E++++ E+E ++ K EEEK+ QE +++QEE+
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 110 KRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
KR++E +E+EE ++ + E L +E R + Q PEE +L S +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEER-REQRLKREEPEEERRQQLLKSEE 638
Query: 170 KNTAFVKKLKTITEQQRD 187
+ ++L+ +++R+
Sbjct: 639 QEERRQQQLRREQQERRE 656
Score = 51.6 bits (122), Expect = 5e-06
Identities = 31/144 (21%), Positives = 76/144 (52%), Gaps = 8/144 (5%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKD-----DIKLTAKKEVSKAPEDKKKR 59
R + E+ LP +EK E+R +ER K+ + + ++E ++ ++++
Sbjct: 799 RAEERQQREQRFLPEEEEK---EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
Query: 60 LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
L++D+ ++ +E+++ + + + EEE K++ K +E+ ++E+Q +++EEE
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 120 QMKEKEESIQLHQEAWERHHLRKE 143
+ +EK + ++ E L++E
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQE 939
Score = 51.2 bits (121), Expect = 6e-06
Identities = 30/156 (19%), Positives = 83/156 (53%), Gaps = 10/156 (6%)
Query: 40 DIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERK---KKDEEKVKAEE-----ESKKKEE 91
+++ ++E + +++ R+ ++ +KE ++R+ +K+EEK++ EE E +++EE
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
Query: 92 EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNA 151
+ +K ++E R++++E+ ++QQ Q++ K+E + Q+ R + + + +
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
Query: 152 PDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRD 187
R E+ R + L++ ++ + + +Q +
Sbjct: 337 QQLRREQE--ERREQQLRREQEEERREQQLRREQEE 370
Score = 50.4 bits (119), Expect = 1e-05
Identities = 36/151 (23%), Positives = 84/151 (55%), Gaps = 12/151 (7%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKE---VSKAPEDKK 57
ER + EE+ +E+ E +ER + ++ +L ++E + + D+K
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Query: 58 KRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKK---QEEQAKRQQE 114
E+ + ++++++RK +++E ++++E +K EEE++ H+++ ++K +E+Q +RQ+
Sbjct: 1487 FLEEEQQLRRQERDRKFREQE-LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Query: 115 EEAAAQMKEKE--ESIQLHQEAWERHHLRKE 143
+ Q ++++ E QL QE E+ R+E
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Score = 49.7 bits (117), Expect = 2e-05
Identities = 31/147 (21%), Positives = 74/147 (50%), Gaps = 6/147 (4%)
Query: 5 RKKPASMEEKDSLPNNKEK----DCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
+++ E++ L K K D +R + + P+ + + K K E+++ R
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
+D + ++ + ++D + + E++ + +E+E ++ Q + +EEQ +R++++EA +
Sbjct: 1253 LEDSQLRD--RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
Query: 121 MKEKEESIQLHQEAWERHHLRKELRSK 147
++ +E QL +E E R+E K
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRK 1337
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 16/163 (9%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK-RLEDDKRKKEDK 70
E ++ + +E+D R R + + K ++ + E +++ R E D++ +ED+
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625
Query: 71 E-----------RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
+ R+++D + ++ E + +++E E++ +H + + ++EEQ ++ EE+
Sbjct: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
Query: 120 QM----KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
+ K +EE QL ++ ER L++E + + Q EE
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728
Score = 49.7 bits (117), Expect = 2e-05
Identities = 32/126 (25%), Positives = 67/126 (53%), Gaps = 14/126 (11%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPE-DKKKRLEDD 63
+++ E++ L +E+ + K R ++ ++ +++ + + D K R E++
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 64 KRKKEDKERKKKDE-------EKVKAEEESKKKE------EEEKKKHQEEERKKQEEQAK 110
+ + E++E++ + E E+ A +E ++E EEE+K+ QE ERK +EE +
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Query: 111 RQQEEE 116
RQQ+EE
Sbjct: 1887 RQQKEE 1892
Score = 49.3 bits (116), Expect = 2e-05
Identities = 35/123 (28%), Positives = 61/123 (49%), Gaps = 6/123 (4%)
Query: 44 TAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK 103
T E +A D K+ L D+R++ED+ R + + ++ EE + +K++ QE E
Sbjct: 93 TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQL---EEEPGQRRRQKRQEQERELA 149
Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKE---LRSKNQNAPDSRPEENF 160
+ EEQ+++Q+ E + + EE + QE ER R E L+S + + P+E
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
Query: 161 FSR 163
R
Sbjct: 210 LRR 212
Score = 49.3 bits (116), Expect = 2e-05
Identities = 43/219 (19%), Positives = 94/219 (42%), Gaps = 39/219 (17%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDI---------KLTAKKEVSKAPE 54
+R+ ++ +E+ E + S K ++ +L + + +
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Query: 55 DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEE--------------------- 93
+++R D+ +E++E++ + E V +EE K +EEE
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 94 KKKHQEEERKKQ----EEQAKRQQEEEAAAQMKEKEESIQLHQEAWER--HHLRKELRSK 147
+++ QEEE+++Q E+Q +R+QEEE Q +E+ E + ++ ER LR+E +
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346
Query: 148 NQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
+ EE R + L++ ++ + + +Q+
Sbjct: 347 REQQLRREQEE---ERREQQLRREQEEERREQQLRREQQ 382
Score = 49.3 bits (116), Expect = 2e-05
Identities = 37/177 (20%), Positives = 87/177 (49%), Gaps = 2/177 (1%)
Query: 21 KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKV 80
+E++ +E ++ER K I + S+A + ++ ++ RK+E + R+++ EEK
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEA-DARQSKVYSRPRKQEGQRRRQEQEEKR 739
Query: 81 KAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHL 140
+ E + +EEE+ Q++E +++ + + Q EE + + +++ + +E ER
Sbjct: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799
Query: 141 RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR-DSLSHDFNGL 196
+E + + Q E+ R +K F+++ + + ++R L + +GL
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGL 856
Score = 49.3 bits (116), Expect = 2e-05
Identities = 33/163 (20%), Positives = 82/163 (50%), Gaps = 5/163 (3%)
Query: 34 KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE--RKKKDEEKVKAEEESKKKEE 91
+ER + + + + E K +R E +++ ED++ R+++ +++++ E + K +E+
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624
Query: 92 EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNA 151
E+ + +EE++ ++E+ ++ EEE + +E+E+ QL + + ++L + +
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ--QLRHDRDRKFREEEQLLQEGEEQ 1682
Query: 152 PDSRPE-ENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDF 193
R E + F + L++ K L+ + +R L F
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Score = 48.9 bits (115), Expect = 3e-05
Identities = 34/143 (23%), Positives = 71/143 (49%), Gaps = 4/143 (2%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
+++ EEK ++ + E R ++ + T + + + E ++RL
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEE-EKKKHQEEERKKQ---EEQAKRQQEEEAAAQ 120
+E +ER+ + EE+ + E+ +EEE E+++ Q ER+K+ E+ ++ Q E A Q
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 121 MKEKEESIQLHQEAWERHHLRKE 143
++E+E+ +Q QE R++
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRD 871
Score = 47.8 bits (112), Expect = 7e-05
Identities = 36/195 (18%), Positives = 91/195 (46%), Gaps = 16/195 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
E ++ + +E+D R + D K ++ S+ PE K E +++ +
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
+ ++E++++ +E +++ ++ +K +EEE+ +QE + ++ +E + + +E+ ++
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591
Query: 132 QEAWERHHLRKELRSKNQNAPDS-RPEENFFSRLDSSL------------KKNTAFVKKL 178
++ ER + E + + Q R E + R D L +++ F+++
Sbjct: 1592 EQ--ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE 1649
Query: 179 KTITEQQRD-SLSHD 192
+ Q+R+ L HD
Sbjct: 1650 PQLRRQEREQQLRHD 1664
Score = 47.8 bits (112), Expect = 7e-05
Identities = 25/114 (21%), Positives = 63/114 (55%), Gaps = 5/114 (4%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK- 70
+E D +E+ ER + + +D ++++ ++++ R E D++ + ++
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ 1850
Query: 71 ----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
E+ +++E+++ EEE K+++E E+K +E R++Q+E+ + +Q E +Q
Sbjct: 1851 FATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Score = 47.4 bits (111), Expect = 9e-05
Identities = 30/185 (16%), Positives = 90/185 (48%), Gaps = 5/185 (2%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E++ EE+ + ++ ERR + R + + ++ + ++++ +
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
+ ++E +E ++ E++++ E++ +++++ +++ E++ + EQ R++++ Q
Sbjct: 363 QLRREQEEERR--EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK--LKTI 181
+E+ ++ QE ERH + E + Q + E + + + +++ +K LK
Sbjct: 421 REQQLRREQEE-ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 182 TEQQR 186
E++R
Sbjct: 480 QEEER 484
Score = 47.4 bits (111), Expect = 9e-05
Identities = 37/161 (22%), Positives = 82/161 (50%), Gaps = 19/161 (11%)
Query: 36 RPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERK-KKDEEKVKAEEESKKKEEEEK 94
+ + ++ +++ + D+K R E+ + +++++RK +++E++V+ +E +K EEE+
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 95 KKHQEEE--RKKQEEQAKRQQEEEAAAQMKEK-----EESIQLHQEAWERHHLRKELRSK 147
+ +E RK +EE+ Q+ EE +E+ EE QL ++ +R +ELRS+
Sbjct: 1454 QL--RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Query: 148 NQNAPDSRPEENFFSRLDS--SLKKNTAFVKKLKTITEQQR 186
PE F ++ F+++ + + Q+R
Sbjct: 1512 -------EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Score = 47.0 bits (110), Expect = 1e-04
Identities = 39/174 (22%), Positives = 88/174 (50%), Gaps = 20/174 (11%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKE---VSKAPEDKK 57
E+K +E+ + + ++ E + +ER + +D +L ++E + + D+K
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 58 KRLEDDKRKKE--------DKERKKKDEEKV--KAEEESKKKEEEEKKKHQEEERKKQEE 107
E+ + +++ D++RK ++EE++ + EE+ +++E ++K +EE++ +++E
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 108 QAKRQQEEEAAAQMKEKE----ESIQLHQEAWERHHLRKELRSKNQNAPDSRPE 157
+ ++ +EE + +E E E QL QE + R+E K RPE
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Score = 45.4 bits (106), Expect = 3e-04
Identities = 33/193 (17%), Positives = 92/193 (47%), Gaps = 10/193 (5%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAP---EDKKKRLE 61
R++ + ++ ++ ++++ E+R + + ++ ++ +S P E ++++L
Sbjct: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799
Query: 62 DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQM 121
++R++ ++ ++EEK + + +++E+E + +EE+ +++E + Q+EE+ +
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED 859
Query: 122 KEKEES-IQLHQEAW------ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
+E+ S Q + W ER R L +K R E+ + L++
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 175 VKKLKTITEQQRD 187
++ + Q R+
Sbjct: 920 KRRRQEQERQYRE 932
Score = 45.1 bits (105), Expect = 4e-04
Identities = 39/167 (23%), Positives = 84/167 (50%), Gaps = 20/167 (11%)
Query: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL-- 60
A R++ + +D + ++ SER RP L ++E E++++R
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP----LREQRERQLRAEERQQREQR 809
Query: 61 ---EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
E++++++ ++R+++++E EEE + + E ++ QEEE QE+Q +R++ +E
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ-ERRRSQE- 867
Query: 118 AAQMKEKEESIQLHQEAWERHH-------LRKELRSKNQNAPDSRPE 157
Q ++++ QL +E R H L+++LR + Q + E
Sbjct: 868 --QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/107 (23%), Positives = 60/107 (56%), Gaps = 6/107 (5%)
Query: 13 EKDSLPNNKEKDCSERRTVSSKER-PKDDIKLTAKKEVSKAPEDKKKRLED-----DKRK 66
E++ L +E+ + K R ++ ++L +++ + D++ R E+ +K +
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
Query: 67 KEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQ 113
+E++E +++E+K + E E K +EE +++ +EE+R +Q + K Q+
Sbjct: 1859 REEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 41.6 bits (96), Expect = 0.005
Identities = 36/180 (20%), Positives = 78/180 (43%), Gaps = 24/180 (13%)
Query: 10 SMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED 69
++ + L K C + ++ R ++D + E + ++LE++ ++
Sbjct: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEED---------QRRFEPRDRQLEEEPGQRRR 138
Query: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQE---------EERKKQEEQAKRQQEEEAAAQ 120
++R++++ E + EE+S+K+E E++ Q +E +++EE R+ EEE
Sbjct: 139 QKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE---RRAEEEQLQS 195
Query: 121 MKEKEESIQLHQEAWERH---HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
K E +E R LR++ R + Q R + F + +K ++K
Sbjct: 196 CKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255
Score = 41.6 bits (96), Expect = 0.005
Identities = 39/181 (21%), Positives = 86/181 (47%), Gaps = 33/181 (18%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDI-------KLTAKKEVSKAPE-- 54
+ +K A + K+SL ++ ++ +RR + +++ + ++E+++ E
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
Query: 55 DKKKRLEDDKRKKEDKE-----RKKKDEEKVKAEEESKKK-----------EEEEKKKHQ 98
+K++RLE R++ D+E ++ ++ E+ +AEEE + EE+ +++
Sbjct: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
Query: 99 EEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHH--LRKELRSKNQNAPDSRP 156
E R+K E+ ++Q+ E +E+EE + W + LRKE + P +
Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 157 E 157
E
Sbjct: 270 E 270
Score = 40.4 bits (93), Expect = 0.011
Identities = 30/203 (14%), Positives = 98/203 (48%), Gaps = 22/203 (10%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSK--ERPKDDIKLTAKKEVSKAPEDKKKRLE 61
ER+K E + +E E + + + +R + +++ ++E E+++ E
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186
Query: 62 DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---------- 111
+ +++++++ER+ ++EE+++ ++ ++ +E+++ + + + ++E A R
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 112 ----QQEEEAAAQMKEKEESIQL---HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRL 164
+Q E++ + ++ ++ +Q Q+ +R R+ + ++++ P+ EE
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE---EEQLEREE 1303
Query: 165 DSSLKKNTAFVKKLKTITEQQRD 187
K+ ++ K + ++R+
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREERE 1326
Score = 39.7 bits (91), Expect = 0.019
Identities = 33/193 (17%), Positives = 90/193 (46%), Gaps = 11/193 (5%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E + A + S P +E + + R + +++ ++ + +++++R D
Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR-RDF 767
Query: 64 KRKKEDKERKKKDEEKVKAE---EESKKKEEEEKKKHQEEER----KKQEEQAKRQ-QEE 115
+ + +E+ ++ +++ A E ++++ +++ Q E+R ++++EQ +RQ +E
Sbjct: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
Query: 116 EAAAQMKEKEESIQLHQEAWERHHLRKELR--SKNQNAPDSRPEENFFSRLDSSLKKNTA 173
E Q E+EE +Q + A + L+ + + + + R ++ + +L+ K+
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 174 FVKKLKTITEQQR 186
+ + EQ R
Sbjct: 888 TLYAKPALQEQLR 900
Score = 37.4 bits (85), Expect = 0.092
Identities = 49/239 (20%), Positives = 96/239 (40%), Gaps = 6/239 (2%)
Query: 993 LEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEV 1052
L+E Q++ LER+ L + ++ + + + L +EEE E +E+ + E
Sbjct: 271 LQEEEEQLRKLERQEL-RRERQEEEQQQQRLRREQQLRRKQEEER--REQQEERREQQER 327
Query: 1053 NEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDED 1112
E +EE E EE E+ + + + E + L+ + E
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 1113 FIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFV 1172
++ ++ E +R + + QL L + QLR+ E + E
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ-- 445
Query: 1173 MLTRKGNKQQFKILNVPMSSQLAANHWNQQ-QAEQEERMRMKKLTLDINERQEQEDYQE 1230
L R+ +++ + + + QQ + +QEE R + L L+ ER+EQ++ +E
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
Score = 36.2 bits (82), Expect = 0.21
Identities = 44/235 (18%), Positives = 92/235 (39%), Gaps = 18/235 (7%)
Query: 1018 DSKDSMTEGENLEEDE----------EEEEGGAETEEQSGNESEVNEPEE----EEGSDN 1063
D K+S+ + EED+ EEE G +++ E E+ E EE +E +
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ 163
Query: 1064 DDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLE 1123
D + +EE +E +EE + KG + P DE+ ++ + + L
Sbjct: 164 RDRQRRDEELWRQRQEWQEREERRAEEEQLQ-SCKGHETEEFP---DEEQLRRRELLELR 219
Query: 1124 NLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQF 1183
+ + + + D + + RK + E E + ++ +Q
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 1184 KILNVPMSSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQR 1238
K+ + + QQ+ +E+++R K+ +++E+ + QE + +R
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Score = 35.4 bits (80), Expect = 0.35
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 20/146 (13%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDKDSK-DSMTEGENLEEDE----EEEEGGAETEEQSGN 1048
E R+ Q+ ER++ K L +++ E L+E E EEEE E E+ G
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 1049 ESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCV 1108
E E +E E ++E ++EEE+ + + E + + C
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ---------------CR 1111
Query: 1109 EDEDFIQALDKMMLENLQQRSGESVK 1134
E+E+ Q ++++ E ++R + ++
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELE 1137
Score = 35.4 bits (80), Expect = 0.35
Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 5/141 (3%)
Query: 993 LEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEED--EEEEEGGAETEEQSGNES 1050
LE R+ +++++E L +K + + EE+ +EEE+ E +E+ E
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 1051 EVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVED 1110
E EEEE + +E++ +D E E + +V KG + +ED
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
Query: 1111 EDFIQALDKMMLENLQQRSGE 1131
Q D+ ++LQ GE
Sbjct: 1256 S---QLRDRQSQQDLQHLLGE 1273
Score = 34.7 bits (78), Expect = 0.60
Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 11/102 (10%)
Query: 995 ESIRQVQDLEREFLIKLGLVNDKDSKDSMTE--GENLEEDEEEEEGGAETEEQSGNESEV 1052
E RQ++D + + D+ S+ + GE E D E+E + ++ E E
Sbjct: 1248 EQFRQLEDSQ---------LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298
Query: 1053 NEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
E EE++ + D + +EE++ + + + ETD + E
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Score = 34.7 bits (78), Expect = 0.60
Identities = 54/275 (19%), Positives = 105/275 (38%), Gaps = 18/275 (6%)
Query: 990 CNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNE 1049
C E+ +RQ D +R+F + ++ ++ E E +E E E E+Q E
Sbjct: 1401 CQEREQQLRQ--DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 1050 SEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSN--KENETDEENTEVMIKGGGLKHVPC 1107
EEE+ +++ +E + +L + + E D + E ++ +
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
Query: 1108 VEDEDF--IQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAES 1165
E++ Q K + E Q R E + + D + QLR+ E E +
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ-------EREEQQ 1571
Query: 1166 ADTM----PFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKKLTLDINE 1221
F + +K +Q+ + + QL QQQ QE + ++ + E
Sbjct: 1572 LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE-GQQQLRQERDRKFREDEQLLQE 1630
Query: 1222 RQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPK 1256
R+EQ+ +++ P +ER + +H +
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665
Score = 33.9 bits (76), Expect = 1.0
Identities = 53/270 (19%), Positives = 108/270 (40%), Gaps = 21/270 (7%)
Query: 999 QVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEE 1058
Q+Q E + L + + ++ + + +EE+ G E E++ E E EEE
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994
Query: 1059 EGSDNDDD--EGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVE----DED 1112
E ++ E E+ ++ K++E +E +++ + + + E +E+
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054
Query: 1113 FIQALDKMML--ENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGE------GEAE 1164
+Q ++ +L E +R E + ++ + + + LR+ P + E E
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114
Query: 1165 SADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQ---EERMRMKKLTLDINE 1221
+L + K++ + Q QQ+ EQ EE + ++ L+
Sbjct: 1115 ELQQEEEQLLREEREKRR----RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 1222 RQEQEDYQEMLQSLAQRPAPANTNRERRPR 1251
R+E+E QE Q L + RER+ R
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYR 1200
Score = 32.7 bits (73), Expect = 2.3
Identities = 60/321 (18%), Positives = 124/321 (38%), Gaps = 47/321 (14%)
Query: 956 KKSLEVWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVN 1015
K+ + W + + ++ L R K +L E R+ ++L++E LG
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRL-QERERQYREEEELQQEEEQLLG--- 1065
Query: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
+ +++ E + +EEE E E+ E E +E E +++E ++EEE+
Sbjct: 1066 --EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 1076 TDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKV 1135
+ + E + + E + V E++ + +K + L+++ E ++
Sbjct: 1124 LREEREKRRRQELERQYREE-------EEVQQEEEQLLREEPEKRRRQELERQYREEEEL 1176
Query: 1136 HQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLA 1195
Q + + + + R+ E E L R+ KQ+++ Q +
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEE----------LQRQKRKQRYR-----DEDQRS 1221
Query: 1196 ANHWNQQQAEQEERMRMKKL--------------TLDINERQEQEDYQEMLQSLAQRPAP 1241
W Q + E+E +R K+ + +RQ Q+D Q +L +R
Sbjct: 1222 DLKW-QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER--- 1277
Query: 1242 ANTNRERRPRYQHPKGAPNAD 1262
+ +ERR Q + P +
Sbjct: 1278 -DREQERRRWQQRDRHFPEEE 1297
Score = 32.0 bits (71), Expect = 3.9
Identities = 64/302 (21%), Positives = 115/302 (38%), Gaps = 50/302 (16%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVN 1053
E+ +R+ Q+ RE +K ++ + +E + E EE E + EE+ E E
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 1054 EP----EEEEGSD----NDDDEGE-----EEEEENTDYLTDSNKENETDEENTEVMIK-- 1098
E E+EE D +++ + E+EE L E EE E +K
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623
Query: 1099 -GGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLK---SQLRKGP 1154
+ ++ E+ + + + Q+R + +K + + + LK + R+
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Query: 1155 PLGGGEGEAESADTMPFV-----MLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEER 1209
L E E + L + + +Q K+ + P + +++ EQEE+
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE-----GQRRRQEQEEK 738
Query: 1210 MRMKKLTLDINE-----RQEQEDYQEM---------------LQSLAQRPAPANTNRERR 1249
R ++ L E RQ+QE+ Q Q L+ RP P RER+
Sbjct: 739 RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP-PLREQRERQ 797
Query: 1250 PR 1251
R
Sbjct: 798 LR 799
Score = 30.8 bits (68), Expect = 8.6
Identities = 55/282 (19%), Positives = 110/282 (39%), Gaps = 17/282 (6%)
Query: 981 ELLRPKIKLCNSLEESIRQVQDL------EREFLIKLGLVNDKDSKDSMTEGENLEEDEE 1034
ELL + K ++ R+ QD E+E+ + ++ ++ K E + E +E
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 1035 EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
EEE + E Q E ++++ + ++EEE + + ++ E E+ E
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 1095 VMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGP 1154
+ + E + + ++ + L++ E + QL L + QLR+
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Query: 1155 PLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKK 1214
L + L R +QQ + Q H +Q+ EQE R ++
Sbjct: 394 QLRREQQLRREQQLRREQQLRR---EQQLRREQQLRREQEEERH--EQKHEQER--REQR 446
Query: 1215 LTLDINERQE----QEDYQEMLQSLAQRPAPANTNRERRPRY 1252
L + ER++ +E+ + Q ++ + ERR R+
Sbjct: 447 LKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Score = 30.8 bits (68), Expect = 8.6
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 3/105 (2%)
Query: 993 LEESIR--QVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNES 1050
LE+ ++ +V+ LE+E + L ++ ++ + EE EE + E+Q E
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Query: 1051 EVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEV 1095
+ EEEE + + E EEE L + +E + + +
Sbjct: 658 RLKREEEEERLE-QRLKREHEEERREQELAEEEQEQARERIKSRI 701
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 72.0 bits (175), Expect = 3e-12
Identities = 40/149 (26%), Positives = 82/149 (55%), Gaps = 12/149 (8%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKE-- 68
M E+ LP KEK + ++ + + K+ ++++ K ++++K+ D ++ +E
Sbjct: 654 MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 69 ---DKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE----EQAKRQQEEEAAAQM 121
++E+K ++EE++ E+E K +E+EEK + QEEE +QE EQ ++ E++ +
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 122 KEK---EESIQLHQEAWERHHLRKELRSK 147
KEK E +Q ++ WE+ ++ K
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802
Score = 65.5 bits (158), Expect = 3e-10
Identities = 42/138 (30%), Positives = 82/138 (59%), Gaps = 12/138 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK--RKKED 69
E+++ + +EK ++R KE+ + K+ +E K E ++K E +K +K ++
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM---QEQEKMQEQEEKIWEQEKMEKKTQE 698
Query: 70 KERKKKDEEKVKAEE---ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEE 126
+E+K D+EK++ EE E +KK EE++ +E+E K QE++ K Q++EE +M E+EE
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE---EMWEQEE 755
Query: 127 SI-QLHQEAWERHHLRKE 143
+ + ++ WE+ L ++
Sbjct: 756 KMWEQEEKMWEQQRLPEQ 773
Score = 63.9 bits (154), Expect = 9e-10
Identities = 47/204 (23%), Positives = 98/204 (48%), Gaps = 14/204 (6%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ E++ + +EK + + +E + + ++ + E +K+ E +K
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 65 RKKEDKERKKKDEEKVKAEE-----ESKKKEEEEKKKHQEE---ERKKQ---EEQAKRQQ 113
+E KE ++++E+ + EE E K +E+EEK QEE E++KQ +EQ R Q
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 114 EE---EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
EE E +++EKEE ++ ++ WE+ +E + + +R +E + ++
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 171 NTAFVKKLKTITEQQRDSLSHDFN 194
++ +T+ EQ+ + N
Sbjct: 456 EKKMREEEETMREQEEKMQKQEEN 479
Score = 62.8 bits (151), Expect = 2e-09
Identities = 39/135 (28%), Positives = 79/135 (58%), Gaps = 12/135 (8%)
Query: 11 MEEKDSLPNNKEKDCSER--RTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKE 68
M E++ ++E+ E+ R +ER ++ K+ ++V K E+KK +++ ++K
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMW--EQVEKMREEKK--MQEQEKKTR 440
Query: 69 DKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI 128
D+E K ++EE+++ E E K +EEEE + QEE+ +KQEE Q+E+E Q +++
Sbjct: 441 DQEEKMQEEERIR-EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK-- 497
Query: 129 QLHQEAWERHHLRKE 143
++ WE+ ++++
Sbjct: 498 ---EKLWEQEKMQEQ 509
Score = 62.8 bits (151), Expect = 2e-09
Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 18/195 (9%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK-KEVSKAPEDKKKRLEDDKRKKEDK 70
EEK K D ER ++E+ K K +E + E +KK E+++ +E +
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 71 ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ---------- 120
E+ ++ EEK++ E+E K E+EEK + QEE+ +QEE+ Q+E+ Q
Sbjct: 610 EKMQEQEEKMQ-EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 121 ----MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRP--EENFFSRLDSSLKKNTAF 174
M+E+E+ + ++ WE+ + K+ + + + D EE + +++
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 175 VKKLKTITEQQRDSL 189
+++ + ++Q + +
Sbjct: 729 MREQEEKMQEQEEKM 743
Score = 62.4 bits (150), Expect = 3e-09
Identities = 39/176 (22%), Positives = 91/176 (51%), Gaps = 11/176 (6%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
ER + + E++ + +EK E R +++ +++ ++ ++E K E ++K E +
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKMQEQEEKMQEQE 623
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEE---------EKKKHQEEERKKQEEQAKRQQE 114
++ E +E+ ++ EEK+ +EE ++EE E+K+ E K QE++ ++QE
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE 683
Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
E+ Q K ++++ + ++ W++ +R+E S + R EE + +++
Sbjct: 684 EKIWEQEKMEKKTQEQEKKTWDQEKMREE-ESMREREKKMREEEEMMREQEEKMQE 738
Score = 60.8 bits (146), Expect = 8e-09
Identities = 39/133 (29%), Positives = 82/133 (61%), Gaps = 11/133 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
E++D + +EK + + + +E + K T ++E K D+++++ +++R +E +E
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERME--KKTQEQE--KKTWDQEEKMREEERMRE-RE 595
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI-QL 130
+K ++EE++ E+E K +E+EEK QE+E K E++ K Q++EE +M E+EE + +
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEK--MQEQEEKMWEQEEKMQEQEE---KMWEQEEKMWEQ 650
Query: 131 HQEAWERHHLRKE 143
++ WE+ L ++
Sbjct: 651 EEKMWEQQRLPEQ 663
Score = 59.7 bits (143), Expect = 2e-08
Identities = 42/154 (27%), Positives = 82/154 (53%), Gaps = 18/154 (11%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
E+++ + +EK + + +E + + +++ K + +++ E D+R +E +E
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Query: 72 RKKKDE---EKVKAEEESKKKEEEEKK------KHQEEERKKQEEQAKRQQEEEAAAQMK 122
R ++ E E+V+ E KK +E+EKK K QEEER ++ E+ R++EE M+
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE----TMR 467
Query: 123 EKEESIQLHQE-AWERHHLRKELRSKNQNAPDSR 155
E+EE +Q +E WE ++E + Q P+ +
Sbjct: 468 EQEEKMQKQEENMWE----QEEKEWQQQRLPEQK 497
Score = 59.7 bits (143), Expect = 2e-08
Identities = 39/151 (25%), Positives = 79/151 (52%), Gaps = 8/151 (5%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
+P +++K + E++ + +EK + + +E K ++E + ED+
Sbjct: 493 LPEQKEK---LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE---EA 117
E+ R +E K +++ + K +E+ KK ++E+K +EEER ++ E+ R++EE E
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM-REEERMREREKKMREEEEMMREQ 608
Query: 118 AAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
+M+E+EE +Q +E WE+ +E K
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Score = 59.3 bits (142), Expect = 2e-08
Identities = 37/150 (24%), Positives = 78/150 (52%), Gaps = 6/150 (4%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
E+++ + + +E E++ ++ + + ++ ++E + E K E+ KK ++
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE--EEAAAQMKEKEESIQ 129
KK +++ K EE + +E E+K + +EE ++QEE+ + Q+E +E +M E+EE +Q
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634
Query: 130 LHQE-AWERHHLRKELRSK---NQNAPDSR 155
+E WE+ E K Q P+ +
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664
Score = 58.9 bits (141), Expect = 3e-08
Identities = 41/200 (20%), Positives = 101/200 (50%), Gaps = 23/200 (11%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
++ M+E++ ++E+ E + +E+ K+ ++E + E+K ++ E++
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREK-----KMREEEETMREQEEKMQKQEENMW 481
Query: 66 KKEDKE--RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEE-----------QAKRQ 112
++E+KE +++ E+K K E+ K +E+EEK QEE+ + QEE + R+
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 113 QEE---EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLK 169
QE+ E +M+++E+ + +E E+ +E ++ +Q + EE + ++
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE--EKMREEERMREREKKMR 599
Query: 170 KNTAFVKKLKTITEQQRDSL 189
+ +++ + ++Q + +
Sbjct: 600 EEEEMMREQEEKMQEQEEKM 619
Score = 58.2 bits (139), Expect = 5e-08
Identities = 40/184 (21%), Positives = 96/184 (52%), Gaps = 8/184 (4%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R+K M E++ + EK E++ +++ +D + ++E + E +KK E+++
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE--RIREREKKMREEEE 464
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
+E +E+ +K EE + +EE + +++ E+K+ E+ K QE++ K ++EE +++
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE---KIR 521
Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTIT 182
++EE ++ W + +R++ + R +E + ++K T +K KT
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK-KTWD 580
Query: 183 EQQR 186
++++
Sbjct: 581 QEEK 584
Score = 57.8 bits (138), Expect = 7e-08
Identities = 37/151 (24%), Positives = 80/151 (52%), Gaps = 7/151 (4%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED--DKRKKED 69
++++++ +EK+ ++R KE+ + K+ ++E E+K + E+ + KK
Sbjct: 475 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 534
Query: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEE--ERKKQEEQAKRQQEEEAAAQMKEKEES 127
++ K +++E E+E K +++E+K QEE E+K QE++ K +EE +M+E+E
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE---KMREEERM 591
Query: 128 IQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
+ ++ E + +E K Q + E+
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQ 622
Score = 57.4 bits (137), Expect = 9e-08
Identities = 44/172 (25%), Positives = 85/172 (49%), Gaps = 26/172 (15%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M + +K EEK K ++ E+ ++ + + K+ E + PE K+K
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW---EQQRLPEQKEKLW 668
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK-------------HQEEERKKQEE 107
E +K +++E+ ++ EEK+ +E+ +KK +E++KK + E++ ++EE
Sbjct: 669 EHEKM--QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 108 QAKRQQEEEAAAQMKEKEESIQ-LHQEAWERHHLRKELRSK---NQNAPDSR 155
+ R+QEE +M+E+EE +Q +E WE+ E K Q P+ +
Sbjct: 727 EMMREQEE----KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Score = 57.0 bits (136), Expect = 1e-07
Identities = 40/185 (21%), Positives = 98/185 (52%), Gaps = 11/185 (5%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDK----KKRLEDDK 64
+ E++ +EK+ E++ + +E + + K+ ++E + E+K ++RL + +
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE---EERKKQEEQAKRQQEEEAAAQM 121
++ ++E+K +D+E+ E++ + +E+EE+ + QE E+ +K E+ K Q++E+
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
+EK + + +E E+ +E + Q + EEN + + + ++ +K K +
Sbjct: 443 EEKMQEEERIRER-EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-L 500
Query: 182 TEQQR 186
EQ++
Sbjct: 501 WEQEK 505
Score = 57.0 bits (136), Expect = 1e-07
Identities = 39/162 (24%), Positives = 81/162 (50%), Gaps = 15/162 (9%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ M E++ + +E+ E+ ++ + + K+ ++E + E+K E+
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQE----EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKM 647
Query: 65 RKKEDK--------ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE 116
++E+K E+K+K E K +E+ K +E+EEK QE+ KK +EQ K+ ++E
Sbjct: 648 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707
Query: 117 AAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
+M+E+E + ++ E + +E K Q + E+
Sbjct: 708 ---KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Score = 55.8 bits (133), Expect = 3e-07
Identities = 40/202 (19%), Positives = 102/202 (50%), Gaps = 20/202 (9%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ E+ + + K+ E++T +E+ +++ ++ +++ + E+ + E+
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKM 473
Query: 65 RKKEDK--ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE-------- 114
+K+E+ E+++K+ ++ + E+ +K E+EK + QEE+ +QEE+ + Q+E
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533
Query: 115 ------EEAAAQMKEKEESIQ-LHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSS 167
E QM E+EE ++ Q+ W++ R E +++ Q EE R +
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE-RMEKKTQEQEKKTWDQEEKM--REEER 590
Query: 168 LKKNTAFVKKLKTITEQQRDSL 189
+++ +++ + + +Q + +
Sbjct: 591 MREREKKMREEEEMMREQEEKM 612
Score = 54.3 bits (129), Expect = 7e-07
Identities = 37/131 (28%), Positives = 72/131 (54%), Gaps = 13/131 (9%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
M E+ LP KEK + ++ + + K+ ++E + E+K + E+ R +E+K
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823
Query: 71 -----ERKKKDEEKVKAEEES---KKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
E+ EEK+ +EE ++++ EEK + QEE+ ++QEE+ + Q+E +M+
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEE-----KMR 878
Query: 123 EKEESIQLHQE 133
E+EE ++ +E
Sbjct: 879 EQEEKMRGQEE 889
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/138 (26%), Positives = 75/138 (54%), Gaps = 6/138 (4%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK---K 57
M E + EEK K ++ E+ ++ + + K+ ++E E+K +
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 58 KRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE--E 115
+RL + K K + E K +++EK++ +EE ++E+ +KK QE+E+K +++ R++E
Sbjct: 658 QRLPEQKEKLWEHE-KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Query: 116 EAAAQMKEKEESIQLHQE 133
E +M+E+EE ++ +E
Sbjct: 717 EREKKMREEEEMMREQEE 734
Score = 52.4 bits (124), Expect = 3e-06
Identities = 38/139 (27%), Positives = 69/139 (49%), Gaps = 10/139 (7%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ M E++ +E+ E+ ++ K + E + PE K+K E +K
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 782
Query: 65 RKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQ------QE 114
++++K E K +D+E+ +E K + +EEK + QEE+ QEE+ Q QE
Sbjct: 783 MQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE 842
Query: 115 EEAAAQMKEKEESIQLHQE 133
E+ Q ++ EE +Q +E
Sbjct: 843 EKMWGQEEKMEEKMQGQEE 861
Score = 51.2 bits (121), Expect = 6e-06
Identities = 41/167 (24%), Positives = 82/167 (49%), Gaps = 40/167 (23%)
Query: 21 KEKDCSE----RRTVSSKERPKDDIKL--------TAKKEVSKAPEDKKKRL-------- 60
KE+D R T++++E K + +L + K E+ ++ K++L
Sbjct: 204 KERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLP 263
Query: 61 --------------EDDKRKKEDKERKKKD----EEKVKAEEESKKKEEEEKKKHQEEER 102
E++ R++E K RK+++ +E+ E+E K +E+EEK QE+
Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRL 323
Query: 103 KKQEEQAKRQQEE-EAAAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
++QE++ + Q++E +++E+EE +Q +E WE+ +E K
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Score = 48.1 bits (113), Expect = 5e-05
Identities = 34/122 (27%), Positives = 68/122 (55%), Gaps = 5/122 (4%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
E+++ + +EK ++R KE+ + K+ +E K E ++K + +++ + +E
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM---QEQEKIWEQEEKMRDQEEKMRGQEE 808
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
+ + EEK++ +EE K +EEK QEE+ QEE+ QEE+ +M+ +EE ++
Sbjct: 809 KMRGQEEKMRGQEE-KMWGQEEKMWGQEEKMWGQEEK-MWGQEEKMEEKMQGQEEKMREQ 866
Query: 132 QE 133
+E
Sbjct: 867 EE 868
Score = 46.6 bits (109), Expect = 2e-04
Identities = 40/160 (25%), Positives = 76/160 (47%), Gaps = 12/160 (7%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
M E++S+ ++K E + +E + + +++ + E ++K E +++ E +
Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 71 ---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK------RQQEEEAAAQ- 120
E+K+K E K +E+ K E+EEK + QEE+ + QEE+ + R QEE+ Q
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 121 --MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
M +EE + +E + E + + Q EE
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEE 868
Score = 45.4 bits (106), Expect = 3e-04
Identities = 35/143 (24%), Positives = 73/143 (51%), Gaps = 21/143 (14%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
+K +EK + K ++ R K R ++++ + ++E + E+K + E++
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM-MREQEEKMQEQEEKMQEQEEEMW 751
Query: 66 KKEDK---------ERKKKDEEK------VKAEEESKKKEEEEKKKHQEEERKKQEEQAK 110
++E+K E+++ E+K K +E+ K E+EEK + QEE+ + QEE+ +
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 111 RQQEEEAAAQMKEKEESIQLHQE 133
Q+E +M+ +EE + +E
Sbjct: 812 GQEE-----KMRGQEEKMWGQEE 829
Score = 39.3 bits (90), Expect = 0.024
Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 20/115 (17%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M + +K EEK R K R +++ K+ ++E E+K
Sbjct: 796 MRDQEEKMRGQEEK-------------MRGQEEKMRGQEE-KMWGQEEKMWGQEEKMWGQ 841
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE 115
E+ +E+K EEK++ +EE K +E+EEK + QEE+ ++QEE+ + Q+E+
Sbjct: 842 EEKMWGQEEKM-----EEKMQGQEE-KMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 35.4 bits (80), Expect = 0.35
Identities = 48/241 (19%), Positives = 92/241 (38%), Gaps = 16/241 (6%)
Query: 1017 KDSKDSMTE-GENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
+D ++ M E E L E EE + EQ E + +E+E D +E +EEE
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI 452
Query: 1076 TDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKV 1135
+ +E ET E E M K + E E+ + + L +++ E K+
Sbjct: 453 REREKKMREEEETMREQEEKMQK----QEENMWEQEE--KEWQQQRLPEQKEKLWEQEKM 506
Query: 1136 HQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLA 1195
+ + I + ++R + G E + + M + + Q M Q
Sbjct: 507 QEQEEKI-WEQEEKIRDQEEMWGQEKKMWRQEKM-------REQEDQMWEQEEKMRDQ-E 557
Query: 1196 ANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHP 1255
W+Q++ +++ +K T D E+ +E+ + + +E + + Q
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 1256 K 1256
K
Sbjct: 618 K 618
Score = 34.7 bits (78), Expect = 0.60
Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 10/114 (8%)
Query: 981 ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGA 1040
E LR K + E+ QV+ + E K ++ + + EE +EEE
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREE----------KKMQEQEKKTRDQEEKMQEEERIR 453
Query: 1041 ETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
E E++ E E +EE+ +++ E+EE+E KE ++E +
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Score = 33.5 bits (75), Expect = 1.3
Identities = 25/103 (24%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK----KKR 59
+ +K EEK K + E+ ++ + K+ ++E E+K +++
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 60 LEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER 102
+E+ + +E+K R++ EEK++ +EE K E+E+K +EE+
Sbjct: 852 MEEKMQGQEEKMREQ--EEKMRGQEE--KMREQEEKMRGQEEK 890
Score = 32.3 bits (72), Expect = 3.0
Identities = 33/159 (20%), Positives = 69/159 (43%), Gaps = 4/159 (2%)
Query: 981 ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDK--DSKDSMTEGENLEEDEEEEEG 1038
E +R + K EE +R+ ++ +E K+ +K + ++ M E E E+ E+EE
Sbjct: 589 ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE--EKMWEQEEK 646
Query: 1039 GAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIK 1098
E EE+ + + E +E+ E E+ +E+ E +T E+ + +
Sbjct: 647 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706
Query: 1099 GGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQ 1137
+ E E ++ ++MM E ++ + K+ +
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Score = 32.0 bits (71), Expect = 3.9
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 1020 KDSMTEGENLEEDE----EEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
++ M E E++ E E EEEE E EE+ + E + +EEE + ++ E+EE+
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Query: 1076 TDYLTDSNKENETDEENTE 1094
KE + E +
Sbjct: 766 EQQRLPEQKEKLWEHEKMQ 784
Score = 30.8 bits (68), Expect = 8.6
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Query: 981 ELLRPKIKLCNSLEESIRQVQDL-EREFLIKLGLVNDKDSKDSMTEGENLEEDE-----E 1034
+ L P+++ EE RQ ++L E+E I+ K + + E L E E +
Sbjct: 259 KFLLPQVQTNTLQEEMWRQEEELREQEKKIR------KQEEKMWRQEERLREQEGKMREQ 312
Query: 1035 EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEE 1091
EE+ + + E E+ E E+E + E EE+ +E + + + ++ EE
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369
Score = 30.8 bits (68), Expect = 8.6
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 1021 DSMTEGENLEEDEE----EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENT 1076
+ M E E ++E EE +E+ +T+EQ + + EEE + + EEEE
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 1077 DYLTDSNKENETDEENTEVM 1096
+ ++ E +E E M
Sbjct: 731 EQEEKMQEQEEKMQEQEEEM 750
Score = 30.8 bits (68), Expect = 8.6
Identities = 25/124 (20%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 1018 DSKDSMTEGENLEEDE----EEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE 1073
+ K+ + E E ++E E +EE+ + E+ G E ++ EE+ + G+EE+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 1074 -ENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGES 1132
+ + ++ EE E ++G + E E+ ++ ++ M E ++ G+
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQG---QEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Query: 1133 VKVH 1136
K++
Sbjct: 889 EKIY 892
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 72.0 bits (175), Expect = 3e-12
Identities = 46/148 (31%), Positives = 81/148 (54%), Gaps = 8/148 (5%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R+K M E+ + +EK E++T +++ D + ++E + E K + E+
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
Query: 65 RKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
R++E+K E K +++E+ E+E K +E+EEK QEE+ +QEE+ K Q++EE
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE---M 633
Query: 121 MKEKEESIQLHQE-AWERHHLRKELRSK 147
M E+EE +Q +E WE+ +E K
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEK 661
Score = 67.4 bits (163), Expect = 8e-11
Identities = 44/144 (30%), Positives = 83/144 (57%), Gaps = 12/144 (8%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
M E+D KE+ E++ + +E + K T ++E K D+++++ +++R +E +
Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQE--KKTWDQEEKMREEERMRE-R 565
Query: 71 ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK------ 124
E+K ++EE++ E+E K +E+EEK + QEE+ +QEE K Q++EE + +EK
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE--KMQEQEEKMWEQEEKMWEQEE 623
Query: 125 EESIQLHQE-AWERHHLRKELRSK 147
E+ +Q +E WE+ +E K
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEK 647
Score = 62.8 bits (151), Expect = 2e-09
Identities = 44/180 (24%), Positives = 88/180 (48%), Gaps = 14/180 (7%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ E++ + +EK + + +E + + +++ + E +K+ E +K
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
Query: 65 RKKEDKERKKKDEEKVKAEE-----ESKKKEEEEKKKHQEE---ERKKQ---EEQAKRQQ 113
+E K+ ++++E+ + EE E K +E+EEK QEE E++KQ +EQ R Q
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 357
Query: 114 EE---EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
EE E +++EKEE ++ ++ WE+ +E + R EE + ++K
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417
Score = 62.4 bits (150), Expect = 3e-09
Identities = 35/157 (22%), Positives = 90/157 (57%), Gaps = 3/157 (1%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ + E++ + +EK E R +++ +++ ++ ++E +++K R +++K
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMK 122
+++++ ++++E+ + EE+ ++EEE+K + QEE +QEE+ + Q+E+ E +M+
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656
Query: 123 EKEESIQLHQEAWE-RHHLRKELRSKNQNAPDSRPEE 158
E+EE ++ +E + + +E K Q + E+
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Score = 62.0 bits (149), Expect = 3e-09
Identities = 41/165 (24%), Positives = 92/165 (55%), Gaps = 18/165 (10%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDK----KK 58
R++ + E++ +EK+ E++ + +E + + K+ ++E + E+K ++
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
Query: 59 RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQ----EEERKKQEEQAKRQQE 114
RL + +++ ++E+K +D+E+ E++ + +E+EE+ + Q E+E K QEE+ R++E
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398
Query: 115 E---EAAAQMKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDSR 155
+ E M+E+EE +Q +E WE ++E + Q P+ +
Sbjct: 399 KKMREEEETMREQEEKMQKQEENMWE----QEEKEWQQQRLPEQK 439
Score = 61.2 bits (147), Expect = 6e-09
Identities = 43/170 (25%), Positives = 81/170 (47%), Gaps = 16/170 (9%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M + +K EEK K + E+ +E + + ++ K E ++K
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE---- 116
E +++ +E +E+ ++ EEK++ +EE K +E+EEK + QEE+ ++QEE+ + Q+E+
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEE-KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708
Query: 117 -----------AAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSR 155
+M+EKEE I+ +E + E R P S+
Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758
Score = 59.3 bits (142), Expect = 2e-08
Identities = 45/169 (26%), Positives = 85/169 (50%), Gaps = 16/169 (9%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M E + EEK K ++ E+ ++ + + K+ ++E E++ K
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
E ++ E +E+ ++ EEK+ +EE + E+EEK + QEE+ + QEE+ R+QEE+ Q
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMREQEEKMQGQEEK-MREQEEKMQGQ 686
Query: 121 ---MKEKEESIQLHQE-AW----------ERHHLRKELRSKNQNAPDSR 155
M+E+EE ++ +E W E+ ++E+R K + D +
Sbjct: 687 EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQK 735
Score = 57.8 bits (138), Expect = 7e-08
Identities = 38/146 (26%), Positives = 76/146 (52%), Gaps = 9/146 (6%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M + +K EEK K ER K+ + + K+ ++E +++ +
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371
Query: 61 EDDKRKKE---DKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEA 117
E+ R++E ++E K ++EE+++ E E K +EEEE + QEE+ +KQEE Q+E+E
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIR-EREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 430
Query: 118 AAQMKEKEESIQLHQEAWERHHLRKE 143
Q +++ ++ WE+ ++++
Sbjct: 431 QQQRLPEQK-----EKLWEQEKMQEQ 451
Score = 57.8 bits (138), Expect = 7e-08
Identities = 43/217 (19%), Positives = 106/217 (48%), Gaps = 34/217 (15%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-------- 56
R+K M E++ + +EK E R +++ +++ + ++E +++
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428
Query: 57 ---KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEE----EKKKHQEEERKKQEEQA 109
++RL + K K ++E+ ++ EEK+ +EE + +EE EKK ++E+ ++QE+Q
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488
Query: 110 KRQQEE----------------EAAAQMKEKEESIQLHQEAWERHH-LRKELRSKNQNAP 152
Q+E+ E +++EKEE ++ ++ W++ +R+E +++ Q
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 153 DSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSL 189
EE R + +++ +++ + + +Q + +
Sbjct: 549 TWDQEEKM--REEERMREREKKMREEEEMMREQEEKM 583
Score = 57.4 bits (137), Expect = 9e-08
Identities = 51/206 (24%), Positives = 104/206 (50%), Gaps = 31/206 (15%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
+KK A ++EK L +++ + + V +R + K + + +++ R E++
Sbjct: 186 KKKNAELQEKLRLAESEKSEI--QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 243
Query: 65 RKKEDKERKKKD-----EEKVKAEEESKKKEEEEKKKHQEEERKKQE-----------EQ 108
R++E K RK+++ EE+++ E+E K +E+EEK + QE+ ++QE EQ
Sbjct: 244 REQEKKIRKQEEKMWRQEERLR-EQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 109 AKRQQEEEAAAQMKEK----EESIQLHQEAWERHHLR-----KELRSKNQNAPDSRPEEN 159
K +++EE + +EK EE ++ +E R R K++R + Q D EE
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ--EER 360
Query: 160 FFSRLDSSLKKNTAFVKKLKTITEQQ 185
+ + D L++ +++ + + EQ+
Sbjct: 361 MWEQ-DERLREKEERMREQEKMWEQE 385
Score = 57.4 bits (137), Expect = 9e-08
Identities = 39/134 (29%), Positives = 76/134 (56%), Gaps = 10/134 (7%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED 69
E++D + +EK + + + +E + D +L K+E + E KK +++K ++E
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE--RMREQKKMWQQEEKMREEK 540
Query: 70 K---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMKEK 124
K + KK +++ K EE + +E E+K + +EE ++QEE+ + Q+E+ E +M E+
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 125 EESIQLHQE-AWER 137
EE +Q +E WE+
Sbjct: 601 EEKMQEQEEKMWEQ 614
Score = 56.6 bits (135), Expect = 1e-07
Identities = 40/154 (25%), Positives = 83/154 (53%), Gaps = 18/154 (11%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-----KKRLEDDKRK 66
E+++ + + +E E++ ++ + + ++ ++E + E K ++ E D+R
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516
Query: 67 KEDKERKKKDEEKVKAEE---ESKKKEEEEKK------KHQEEERKKQEEQAKRQQEE-- 115
+E +ER ++ ++ + EE E KK +E+EKK K +EEER ++ E+ R++EE
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
Query: 116 -EAAAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
E +M+E+EE ++ +E WE+ +E K
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Score = 56.6 bits (135), Expect = 1e-07
Identities = 39/142 (27%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVS----KAPEDKKKR 59
E KK E+K K ++ R K R ++++ ++++ K E ++K
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 60 LEDDKRKKEDKERKKKDEEKVKAEEESKKKEE--------EEKKKHQEEERKKQEEQAKR 111
E +++ +E +E+ + EEK+ +EE K +E EEK + QEE+ +QEE+ +
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657
Query: 112 QQEEEAAAQMKEKEESIQLHQE 133
Q+E +M+E+EE +Q +E
Sbjct: 658 QEE-----KMREQEEKMQGQEE 674
Score = 54.7 bits (130), Expect = 6e-07
Identities = 41/185 (22%), Positives = 96/185 (51%), Gaps = 10/185 (5%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R + M E+D KE+ E+ + +E + + ++E E++ R +++K
Sbjct: 355 RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK 414
Query: 65 RKKEDK---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE-EAAAQ 120
+K+++ E+++K+ ++ + E+ +K E+EK + QEE+ +QEE+ + Q+E +
Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
Query: 121 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
M +E+ + + WE+ +++R + Q D EE + + D L++ +++ K
Sbjct: 475 MWRQEKMREQEDQMWEQ---EEKMRDQEQKMWDQ--EERMWEQ-DERLREKEERMREQKK 528
Query: 181 ITEQQ 185
+ +Q+
Sbjct: 529 MWQQE 533
Score = 54.3 bits (129), Expect = 7e-07
Identities = 35/191 (18%), Positives = 94/191 (49%), Gaps = 16/191 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK----------KKRLE 61
++++++ +EK+ ++R KE+ + K+ ++E E+K +K++
Sbjct: 417 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 476
Query: 62 DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE---EQAKRQQEEEAA 118
++ +E +++ + EEK++ +E+ +EE + E R+K+E EQ K Q+EE
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE-- 534
Query: 119 AQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL 178
+M+E++++ + ++ W++ +E + R EE + +++ +++
Sbjct: 535 -KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Query: 179 KTITEQQRDSL 189
+ +Q + +
Sbjct: 594 EEKMWEQEEKM 604
Score = 52.8 bits (125), Expect = 2e-06
Identities = 41/167 (24%), Positives = 83/167 (49%), Gaps = 40/167 (23%)
Query: 21 KEKDCSE----RRTVSSKERPKDDIKL--------TAKKEVSKAPEDKKKRL-------- 60
KE+D R T++++E K + +L + K E+ ++ K++L
Sbjct: 166 KERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLP 225
Query: 61 --------------EDDKRKKEDKERKKKD----EEKVKAEEESKKKEEEEKKKHQEEER 102
E++ R++E K RK+++ +E+ E+E K +E+EEK + QE+
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL 285
Query: 103 KKQEEQAKRQQEE-EAAAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
++QE++ + Q++E +++E+EE +Q +E WE+ +E K
Sbjct: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Score = 52.8 bits (125), Expect = 2e-06
Identities = 38/177 (21%), Positives = 88/177 (49%), Gaps = 11/177 (6%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSER-RTVSSKERP-KDDIKLTAKKEVSKAPEDKKKRLED 62
R++ M E++ +EK E+ + + +E+ ++ KL ++E + E+K E+
Sbjct: 265 REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE 324
Query: 63 DKRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEE-----ERKKQEEQAKRQQ 113
R++E+K E + ++EK E+E K +++EE+ Q+E E + +E++ +Q
Sbjct: 325 KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 384
Query: 114 EEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK 170
EE+ + + +E ++ +E ++++ + +N + +E RL +K
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Score = 52.4 bits (124), Expect = 3e-06
Identities = 36/167 (21%), Positives = 82/167 (49%), Gaps = 17/167 (10%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
+P +++K + E++ + +EK + + +E K ++E + ED+ +
Sbjct: 435 LPEQKEK---LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ---M 488
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE---------ERKKQEEQAKR 111
+ + K D+E+K D+E+ E++ + +E+EE+ + Q++ E KK +EQ K+
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
++E +M+E+E + ++ E + +E K Q + E+
Sbjct: 549 TWDQE--EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Score = 52.0 bits (123), Expect = 4e-06
Identities = 30/135 (22%), Positives = 78/135 (57%), Gaps = 5/135 (3%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERP-KDDIKLTAKKEVSKAPEDKKKRLED 62
E+++ +E+ K+ E++ +ER + D +L K+E + E ++ +
Sbjct: 328 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE----KMWE 383
Query: 63 DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
+ K +++ER ++ E+K++ EEE+ +++EE+ +K +E +++E++ ++Q+ E ++
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443
Query: 123 EKEESIQLHQEAWER 137
E+E+ + ++ WE+
Sbjct: 444 EQEKMQEQEEKIWEQ 458
Score = 41.2 bits (95), Expect = 0.006
Identities = 32/142 (22%), Positives = 67/142 (47%), Gaps = 3/142 (2%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVN 1053
E+ +R+ +++ RE K+ +K + E E+ +E+EE E EE+ + E +
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 1054 EPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDF 1113
+ +E+E + +E +E+EE + +E E E ++G + E E+
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG---QEEKMREQEEK 682
Query: 1114 IQALDKMMLENLQQRSGESVKV 1135
+Q ++ M E ++ G+ K+
Sbjct: 683 MQGQEEKMREQEEKMRGQEEKM 704
Score = 38.1 bits (87), Expect = 0.054
Identities = 47/229 (20%), Positives = 96/229 (41%), Gaps = 11/229 (4%)
Query: 1017 KDSKDSMTEGENLEEDEE---EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE 1073
++ ++ M E E + E EE EEE E E++ E E +EE+ +++ E+EE+
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428
Query: 1074 ENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESV 1133
E KE ++E + + + + D++ + +K M + R E
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQ-EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 487
Query: 1134 KVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQ 1193
Q + K ++ E E + M +K +Q+ K+ + +
Sbjct: 488 MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM---REQKKMWQQEEKMREEKKTQE 544
Query: 1194 LAANHWNQQQ-AEQEERMRMKKLTLDINE---RQEQEDYQEMLQSLAQR 1238
W+Q++ +EERMR ++ + E R+++E QE + + ++
Sbjct: 545 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Score = 35.4 bits (80), Expect = 0.35
Identities = 48/250 (19%), Positives = 106/250 (42%), Gaps = 21/250 (8%)
Query: 993 LEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEV 1052
L E ++++ ++ + + + +K +++ + + EE EEE E E++ E E+
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575
Query: 1053 NEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDED 1112
E+EE +++ E+EE+ + ++ E E E M + E+ED
Sbjct: 576 MR-EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE---------QEEED 625
Query: 1113 FIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFV 1172
+Q ++MM E ++ + K+ + + + + + + G E + +
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE---- 681
Query: 1173 MLTRKGNKQQFKILNVPMSSQLAANHWNQQQA--EQEERMRMKKLTLDINE--RQEQEDY 1228
+G +++ + M Q W Q++ QEE+M ++ + E R ++E
Sbjct: 682 --KMQGQEEKMREQEEKMRGQ-EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKM 738
Query: 1229 QEMLQSLAQR 1238
QE L +R
Sbjct: 739 QERLPEHEER 748
Score = 33.1 bits (74), Expect = 1.7
Identities = 52/241 (21%), Positives = 89/241 (36%), Gaps = 33/241 (13%)
Query: 43 LTAKKEVSKAPEDKKK--------------RLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
++ K +K E KKK R D K+KK + + E
Sbjct: 13 MSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPE----TTTSEGCHS 68
Query: 89 KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKN 148
E+E+K HQ +E ++E +A+ Q E E ++ Q+A R L
Sbjct: 69 PEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDA-ARKFEDGNLGESK 127
Query: 149 QNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQ---QRDSLS-----HDFNGLNLSK 200
A +F L +L + + KK E+ +RD+LS + L K
Sbjct: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKK 187
Query: 201 YIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLL------QVWKKHFEARKEE 254
AE + A+ + S++ V +R P + ++W++ E R++E
Sbjct: 188 KNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247
Query: 255 K 255
K
Sbjct: 248 K 248
Score = 32.3 bits (72), Expect = 3.0
Identities = 51/255 (20%), Positives = 104/255 (40%), Gaps = 30/255 (11%)
Query: 981 ELLRPKIKLCNSLEESIRQVQDL-EREFLIKLGLVNDKDSKDSMTEGENLEEDE-----E 1034
+ L P+++ EE RQ ++L E+E I+ K + + E L E E +
Sbjct: 221 KFLLPQVQTNTLQEEMWRQEEELREQEKKIR------KQEEKMWRQEERLREQEGKMREQ 274
Query: 1035 EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
EE+ + + E E+ E E+E E EE+ +E + + + ++ EE
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK-- 332
Query: 1095 VMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGP 1154
E+ + +K M E Q+ + ++ + D + + ++R+
Sbjct: 333 ------------MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL-REKEERMREQE 379
Query: 1155 PLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAE-QEERMRMK 1213
+ E + + + + + ++ + M Q N W Q++ E Q++R+ +
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ-EENMWEQEEKEWQQQRLPEQ 438
Query: 1214 KLTLDINER-QEQED 1227
K L E+ QEQE+
Sbjct: 439 KEKLWEQEKMQEQEE 453
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 70.9 bits (172), Expect = 8e-12
Identities = 42/139 (30%), Positives = 79/139 (56%), Gaps = 6/139 (4%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+ +K EEK K ++ E ++ + + K+ ++E + E+K +R E+
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 64 KRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EA 117
R++E K E K +++E++ E+E K E+EEK QEE+ ++QEE+ +RQ+E+ E
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Query: 118 AAQMKEKEESIQLHQEAWE 136
+++++EE +Q HQE E
Sbjct: 703 EVRLRQQEEKMQEHQEHLE 721
Score = 67.8 bits (164), Expect = 6e-11
Identities = 44/152 (28%), Positives = 87/152 (57%), Gaps = 6/152 (3%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M + +K EEK K ++ E + +E+ ++ ++T ++E K E ++K
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIRE-QEEKIREQEEKIREQEEMTQEQE-EKMGEQEEKMC 623
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAA 118
E +++ +E +E+ ++ EEK++ E+E K +E+EEK + QEE ++QEE+ Q+E+ E
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIR-EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682
Query: 119 AQMKEKEESIQLHQE-AWERHHLRKELRSKNQ 149
+M+E+EE ++ +E WE+ ++ K Q
Sbjct: 683 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Score = 65.9 bits (159), Expect = 2e-10
Identities = 43/164 (26%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R+K E+++ + +EK + + +E + + ++ K E ++K E ++
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMK 122
+ +E +E ++ EEK+ E+E K E+EEK + QEE+ ++QEE+ + Q+++ E +++
Sbjct: 600 KIREQEEMTQEQEEKM-GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658
Query: 123 EKEESIQLHQE-AWERHHLRKELRSKNQNAPDS--RPEENFFSR 163
E+EE +Q +E WE+ E K Q + R EE + +
Sbjct: 659 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Score = 63.5 bits (153), Expect = 1e-09
Identities = 49/198 (24%), Positives = 106/198 (53%), Gaps = 30/198 (15%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ E ++ + +EK + + +E K+ ++E+ E+K +R E+
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEE-----KMRRQEEMMWEKEEKMRRQEEMM 419
Query: 65 RKKEDKERKKKD-----EEKV-----KAEEESKKKEEEEKKKHQE---EERKKQEEQAKR 111
+KE+K R++++ EEK+ K E+ K +E+EEK++ +E E+ K+QE++AK
Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479
Query: 112 QQEEEAAAQMKEKEESIQLHQE-AW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSS 167
++EE +++E+EE I+ +E W E+ H ++++R + + R E+ R +
Sbjct: 480 WRQEE---KIREQEEKIREQEEKMWRQEEKIHEQEKIREE-----EKRQEQEEMWRQEEK 531
Query: 168 LKKNTAFVKKLKTITEQQ 185
+++ ++ + I EQ+
Sbjct: 532 IREQEEIWRQKEKIHEQE 549
Score = 61.6 bits (148), Expect = 5e-09
Identities = 51/177 (28%), Positives = 94/177 (53%), Gaps = 19/177 (10%)
Query: 22 EKDCSERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKKEDKERKK----- 74
EK+ RR ++ I+ +K E K E ++KR E++K ++++K +++
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480
Query: 75 KDEEKVKAEEESKKKEEEEKKKHQEE---ERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
+ EEK++ E+E K +E+EEK QEE E++K E+ KRQ++EE M +EE I+
Sbjct: 481 RQEEKIR-EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIREQ 535
Query: 132 QEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
+E W E+ H ++E + + Q R EE + + ++ ++ + I EQ+
Sbjct: 536 EEIWRQKEKIHEQEE-KIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE 591
Score = 60.5 bits (145), Expect = 1e-08
Identities = 45/193 (23%), Positives = 102/193 (52%), Gaps = 10/193 (5%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ E+++ + +EK + + +E+ +++ K ++E+ + E+K + E+
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ-EEKIREQEEIW 539
Query: 65 RKK----EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAA 118
R+K E +E+ +K EEK+ +EE K ++EEK + QEE+ +QEE+ + Q+E+ E
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEE-KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 119 AQMKEKEESIQLHQEAW-ERHHLRKELRSKNQNAPDS-RPEENFFSRLDSSLKKNTAFVK 176
+++E+EE Q +E E+ E K Q + R +E + +++ ++
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658
Query: 177 KLKTITEQQRDSL 189
+ + + ++Q + +
Sbjct: 659 EQEEMMQEQEEKM 671
Score = 58.5 bits (140), Expect = 4e-08
Identities = 45/192 (23%), Positives = 99/192 (51%), Gaps = 10/192 (5%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ M EK+ E+ E+ + +E + + + ++E + E K R E+
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAKRQQEE--EAAAQ 120
R++E+K R++ EEK+ +EE ++E+ E++K QE+E ++E+ R+QEE +
Sbjct: 487 REQEEKIREQ--EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Query: 121 MKEKEESIQLHQEAWERHHLR---KELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
+ E+EE I+ +E R + +E + + Q R EE + + +++ +++
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ-EEKIREQEEKIRE 603
Query: 178 LKTITEQQRDSL 189
+ +T++Q + +
Sbjct: 604 QEEMTQEQEEKM 615
Score = 57.8 bits (138), Expect = 7e-08
Identities = 40/131 (30%), Positives = 71/131 (54%), Gaps = 12/131 (9%)
Query: 34 KERPKDDIKLTAKKEVSKA-----PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
KE KL A+ E ++ + ++K +++ +E +E+ ++ EEK++ E+E K
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-EQEEKI 391
Query: 89 KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQE-AWERHHLRKELRSK 147
+E+EEK + QEE ++EE+ +RQ+E M EKEE ++ +E WE+ +EL K
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEE-----MMWEKEEKMRRQEEMMWEKEEKIRELEEK 446
Query: 148 NQNAPDSRPEE 158
R +E
Sbjct: 447 MHEQEKIREQE 457
Score = 57.0 bits (136), Expect = 1e-07
Identities = 50/214 (23%), Positives = 99/214 (46%), Gaps = 33/214 (15%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED-- 62
R+ M E++ + +EK E + ++R + + K+ ++E + E+K + E+
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 63 --------------DKRKKEDKERKKKDEEKVKAEEE-----SKKKEEEEKKKHQEEERK 103
++ K++++E + EEK++ +EE K E+EEK + QEE+
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 104 KQEEQAK------RQQEEEAAAQ---MKEKEESIQLHQE-AWERHHLRKELRSK--NQNA 151
+QEE+ R+QEE+ Q ++E+EE I+ +E E+ + +E K Q
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Query: 152 PDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
EE + + ++ ++ K I EQ+
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654
Score = 56.2 bits (134), Expect = 2e-07
Identities = 42/172 (24%), Positives = 84/172 (48%), Gaps = 16/172 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+ +K EEK K D E+ ++ + + K+ ++E + E+K + E+
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607
Query: 64 KRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE---- 115
+++E+K E K ++E+ E+E K + +EEK + QE++ ++QEE+ + Q+E
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667
Query: 116 -----EAAAQMKEKEESIQLHQEAWERHHLR---KELRSKNQNAPDSRPEEN 159
E +M E+EE +Q +E R + +E+R + Q +E+
Sbjct: 668 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 719
Score = 55.8 bits (133), Expect = 3e-07
Identities = 37/149 (24%), Positives = 79/149 (53%), Gaps = 10/149 (6%)
Query: 47 KEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE 106
++ K E ++K E +++ +E +E+ ++ EEK++ +EE E+EEK + QEE ++E
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE-MMWEKEEKMRRQEEMMWEKE 423
Query: 107 EQAKRQQE---------EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPE 157
E+ +RQ+E E +M E+E+ + ++ E +R++ + + Q A R E
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 158 ENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
E + + ++ ++ + I EQ++
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEK 512
Score = 55.5 bits (132), Expect = 3e-07
Identities = 30/119 (25%), Positives = 64/119 (53%), Gaps = 2/119 (1%)
Query: 10 SMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED 69
+ E+++ + +EK C + + +E + +++ K E ++K E ++ +E
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667
Query: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI 128
+E+ + EEK+ +EE K +E+E+K ++EE+ ++E RQQEE+ + E +I
Sbjct: 668 EEKMWEQEEKMCEQEE--KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 43.1 bits (100), Expect = 0.002
Identities = 39/177 (22%), Positives = 80/177 (45%), Gaps = 12/177 (6%)
Query: 21 KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK------KKRLEDDKRKKEDKERKK 74
KEK+ + + E K +I+L K+ K K + + E D KE +
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340
Query: 75 KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK----EESIQL 130
K + +V+ E + +++++K +E K QE + K Q++EE + +EK EE ++
Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400
Query: 131 HQE-AWERHH-LRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
+E WE+ +R++ + R +E + +++ + + + I EQ+
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 457
Score = 35.0 bits (79), Expect = 0.46
Identities = 27/116 (23%), Positives = 55/116 (47%), Gaps = 8/116 (6%)
Query: 981 ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGA 1040
E +R + + EE IR+ +++ +E K+G + ++ M E E +++EE+
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMG-----EQEEKMCEQEEKMQEQEEK---M 636
Query: 1041 ETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVM 1096
+E+ E E E+EE ++ +E+EE+ + ++ E +E E M
Sbjct: 637 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 692
Score = 33.5 bits (75), Expect = 1.3
Identities = 59/286 (20%), Positives = 113/286 (39%), Gaps = 33/286 (11%)
Query: 994 EESIRQVQDLEREFLIKLG----LVNDKDSKDSMTEGENLEEDE----------EEEEGG 1039
EE IR+ ++ RE K+ ++ +K+ K E E++E E+EE
Sbjct: 381 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 440
Query: 1040 AETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDE---ENTEVM 1096
E EE+ + ++ E EE+ + E E+ +E+ K E +E E E M
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 1097 IKGGGLKH-VPCVEDEDFIQALDKMMLENLQQRSGESV-----KVHQLDVAIPLHLKSQL 1150
+ H + +E+ Q ++M + + R E + K+H+ + I +
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 1151 RKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERM 1210
R+ + E + + + K +Q+ KI + + EQEE+M
Sbjct: 561 RQEEKMHDQEEKIREQEEKVW-RQEEKIREQEEKI----REQEEKIREQEEMTQEQEEKM 615
Query: 1211 RMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPK 1256
++ + E + QE ++M +R +E++ R Q K
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKM-----RRQEEKIREQEKKIREQEEK 656
Score = 33.5 bits (75), Expect = 1.3
Identities = 53/260 (20%), Positives = 104/260 (40%), Gaps = 40/260 (15%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDK-DSKDSMTEGENLEEDEE---EEEGGAETEEQSGNE 1049
EE IR+ ++ RE K+ +K ++ + E E +E EE +EE E EE +
Sbjct: 483 EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 1050 SEVNEPEE-----------EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIK 1098
+++E EE +E +D +E E+EE + +E E E I+
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Query: 1099 GGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGG 1158
E E+ Q ++ M E ++ + K+ + + + + + +
Sbjct: 603 ----------EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652
Query: 1159 GEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKKLTL- 1217
E + + M + +++ M Q ++ EQEE+MR ++ +
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEE------KMCEQ------EEKMQEQEEKMRRQEEKMW 700
Query: 1218 --DINERQEQEDYQEMLQSL 1235
++ RQ++E QE + L
Sbjct: 701 EQEVRLRQQEEKMQEHQEHL 720
Score = 33.1 bits (74), Expect = 1.7
Identities = 38/182 (20%), Positives = 83/182 (45%), Gaps = 19/182 (10%)
Query: 21 KEKDCSE----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
KE+D R T++ +E + + KL K ++ ++ + + + + ++K ++ +
Sbjct: 261 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 320
Query: 77 EEKVKAEEESKKKEEEE---KKKHQEEE-----RKKQEEQAKRQQEEEAAAQMKEK---- 124
+++++AE + KE + K + Q EE R Q+++ K ++EE + +EK
Sbjct: 321 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 380
Query: 125 EESIQLHQE---AWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
EE I+ +E E R+E + R EE + + + ++ +K + I
Sbjct: 381 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 440
Query: 182 TE 183
E
Sbjct: 441 RE 442
Score = 31.2 bits (69), Expect = 6.6
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 7/109 (6%)
Query: 64 KRKKEDK--ERKKKDEEKVKAE-EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
++KK D+ E K+ + + E + +EE K+K+ + + K Q ++++ + + +
Sbjct: 248 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 307
Query: 121 MKEKEESIQL----HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
+K K E +L Q E HL KEL+S + E ++RL+
Sbjct: 308 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 356
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 70.1 bits (170), Expect = 1e-11
Identities = 43/117 (36%), Positives = 75/117 (64%), Gaps = 6/117 (5%)
Query: 48 EVSKAPEDKKKRLEDDKR-KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEE--RKK 104
E +KA + +++R E + R K+E++ERK+++E + + EE ++++EEE+K+ +EEE R+K
Sbjct: 724 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 783
Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK---ELRSKNQNAPDSRPEE 158
QEE +RQ+E+E A + + +EE Q +EA R R+ E R K + + EE
Sbjct: 784 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840
Score = 68.9 bits (167), Expect = 3e-11
Identities = 55/197 (27%), Positives = 112/197 (56%), Gaps = 31/197 (15%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E+ K A +E++ +E + +R ++R +++++ ++ + + E+++KR E++
Sbjct: 724 EKAKAAKLEQE-----RREAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEE 777
Query: 64 ---KRKKEDKERKKKDEE---KVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQ 112
+RK+E+ R+++++E + + EEE ++++EE E+++ +EEER+KQEE R+
Sbjct: 778 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE-LLRK 836
Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
QEEEAA +E+EE+ Q E + LR E + A R EE R + +++
Sbjct: 837 QEEEAAKWAREEEEA----QRRLEENRLRME-----EEAARLRHEEEERKRKELEVQRQ- 886
Query: 173 AFVKKLKTITEQQRDSL 189
K+L +QQ+++L
Sbjct: 887 ---KELMRQRQQQQEAL 900
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/130 (28%), Positives = 76/130 (58%), Gaps = 6/130 (4%)
Query: 45 AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK- 103
A +++ + + K +LE ++R+ E R K++EE+ K +EE ++++EE ++ QEEERK
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAE--MRAKREEEERKRQEELRRQQEEILRRQQEEERKR 773
Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELR---SKNQNAPDSRPEENF 160
++EE+ R+++EEA + +E+E +++ +E ER + LR + + + R +E
Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 833
Query: 161 FSRLDSSLKK 170
+ + K
Sbjct: 834 LRKQEEEAAK 843
Score = 62.0 bits (149), Expect = 3e-09
Identities = 39/141 (27%), Positives = 86/141 (60%), Gaps = 13/141 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E ++ A +++++L +E++ + RR +ER + + L +E + E+++K+ E+
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ-EEL 833
Query: 64 KRKKEDKERK--KKDEEKVKAEEESKKKEEEE--KKKHQEEERKKQEEQA--------KR 111
RK+E++ K +++EE + EE++ + EEE + +H+EEERK++E + +R
Sbjct: 834 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 893
Query: 112 QQEEEAAAQMKEKEESIQLHQ 132
QQ++EA +++++++ QL Q
Sbjct: 894 QQQQEALRRLQQQQQQQQLAQ 914
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 12/118 (10%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSK---APEDKKKRLEDDK-RKK 67
EE+ + ERR + R ++++ ++E +K E+ ++RLE+++ R +
Sbjct: 804 EEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME 863
Query: 68 EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---QQEEEAAAQMK 122
E+ R + +E EE +K+ E +++K +R++Q+E +R QQ+++ AQMK
Sbjct: 864 EEAARLRHEE-----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916
Score = 40.4 bits (93), Expect = 0.011
Identities = 41/216 (18%), Positives = 94/216 (43%), Gaps = 57/216 (26%)
Query: 4 ERKKPASM---EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
ER+K + +E+++ +E++ ++RR ++ R +++ +E E K+K L
Sbjct: 826 ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE----EERKRKEL 881
Query: 61 EDDKRKKEDKERKKKDEEKVKAEE------------------------------------ 84
E ++K+ ++R+++ E + ++
Sbjct: 882 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941
Query: 85 ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK------------EKEESIQLHQ 132
E +K EEE +++ +EE+R++Q E K Q+++ Q K + +++ Q
Sbjct: 942 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1001
Query: 133 EAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
E E ++K+ + + Q+ +R N S L +S+
Sbjct: 1002 E--EARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035
Score = 32.0 bits (71), Expect = 3.9
Identities = 19/70 (27%), Positives = 32/70 (45%)
Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
D+ T G LE+ ++ E+ A EQ E+E+ EEE ++ ++EE
Sbjct: 709 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 768
Query: 1081 DSNKENETDE 1090
+ K E +E
Sbjct: 769 EERKRREEEE 778
Score = 30.8 bits (68), Expect = 8.6
Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 13/97 (13%)
Query: 1009 IKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAET-----------EEQSGNESEVNEPEE 1057
++ G + D +DS+ E ED EEE G ++ +E E E++
Sbjct: 265 VRSGSGSIDDDRDSLPEW--CLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 322
Query: 1058 EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
+EG + D EG EE T+ + +TD E
Sbjct: 323 DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVE 359
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 70.1 bits (170), Expect = 1e-11
Identities = 43/117 (36%), Positives = 75/117 (64%), Gaps = 6/117 (5%)
Query: 48 EVSKAPEDKKKRLEDDKR-KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEE--RKK 104
E +KA + +++R E + R K+E++ERK+++E + + EE ++++EEE+K+ +EEE R+K
Sbjct: 751 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 810
Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK---ELRSKNQNAPDSRPEE 158
QEE +RQ+E+E A + + +EE Q +EA R R+ E R K + + EE
Sbjct: 811 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 867
Score = 68.9 bits (167), Expect = 3e-11
Identities = 55/197 (27%), Positives = 112/197 (56%), Gaps = 31/197 (15%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E+ K A +E++ +E + +R ++R +++++ ++ + + E+++KR E++
Sbjct: 751 EKAKAAKLEQE-----RREAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEE 804
Query: 64 ---KRKKEDKERKKKDEE---KVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQ 112
+RK+E+ R+++++E + + EEE ++++EE E+++ +EEER+KQEE R+
Sbjct: 805 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE-LLRK 863
Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
QEEEAA +E+EE+ Q E + LR E + A R EE R + +++
Sbjct: 864 QEEEAAKWAREEEEA----QRRLEENRLRME-----EEAARLRHEEEERKRKELEVQRQ- 913
Query: 173 AFVKKLKTITEQQRDSL 189
K+L +QQ+++L
Sbjct: 914 ---KELMRQRQQQQEAL 927
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/130 (28%), Positives = 76/130 (58%), Gaps = 6/130 (4%)
Query: 45 AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK- 103
A +++ + + K +LE ++R+ E R K++EE+ K +EE ++++EE ++ QEEERK
Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAE--MRAKREEEERKRQEELRRQQEEILRRQQEEERKR 800
Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELR---SKNQNAPDSRPEENF 160
++EE+ R+++EEA + +E+E +++ +E ER + LR + + + R +E
Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 860
Query: 161 FSRLDSSLKK 170
+ + K
Sbjct: 861 LRKQEEEAAK 870
Score = 62.0 bits (149), Expect = 3e-09
Identities = 39/141 (27%), Positives = 86/141 (60%), Gaps = 13/141 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E ++ A +++++L +E++ + RR +ER + + L +E + E+++K+ E+
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ-EEL 860
Query: 64 KRKKEDKERK--KKDEEKVKAEEESKKKEEEE--KKKHQEEERKKQEEQA--------KR 111
RK+E++ K +++EE + EE++ + EEE + +H+EEERK++E + +R
Sbjct: 861 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 920
Query: 112 QQEEEAAAQMKEKEESIQLHQ 132
QQ++EA +++++++ QL Q
Sbjct: 921 QQQQEALRRLQQQQQQQQLAQ 941
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 12/118 (10%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSK---APEDKKKRLEDDK-RKK 67
EE+ + ERR + R ++++ ++E +K E+ ++RLE+++ R +
Sbjct: 831 EEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME 890
Query: 68 EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---QQEEEAAAQMK 122
E+ R + +E EE +K+ E +++K +R++Q+E +R QQ+++ AQMK
Sbjct: 891 EEAARLRHEE-----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943
Score = 40.4 bits (93), Expect = 0.011
Identities = 41/216 (18%), Positives = 94/216 (43%), Gaps = 57/216 (26%)
Query: 4 ERKKPASM---EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
ER+K + +E+++ +E++ ++RR ++ R +++ +E E K+K L
Sbjct: 853 ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE----EERKRKEL 908
Query: 61 EDDKRKKEDKERKKKDEEKVKAEE------------------------------------ 84
E ++K+ ++R+++ E + ++
Sbjct: 909 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968
Query: 85 ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK------------EKEESIQLHQ 132
E +K EEE +++ +EE+R++Q E K Q+++ Q K + +++ Q
Sbjct: 969 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1028
Query: 133 EAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
E E ++K+ + + Q+ +R N S L +S+
Sbjct: 1029 E--EARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062
Score = 32.0 bits (71), Expect = 3.9
Identities = 19/70 (27%), Positives = 32/70 (45%)
Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
D+ T G LE+ ++ E+ A EQ E+E+ EEE ++ ++EE
Sbjct: 736 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 795
Query: 1081 DSNKENETDE 1090
+ K E +E
Sbjct: 796 EERKRREEEE 805
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 70.1 bits (170), Expect = 1e-11
Identities = 43/117 (36%), Positives = 75/117 (64%), Gaps = 6/117 (5%)
Query: 48 EVSKAPEDKKKRLEDDKR-KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEE--RKK 104
E +KA + +++R E + R K+E++ERK+++E + + EE ++++EEE+K+ +EEE R+K
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 789
Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK---ELRSKNQNAPDSRPEE 158
QEE +RQ+E+E A + + +EE Q +EA R R+ E R K + + EE
Sbjct: 790 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 846
Score = 68.9 bits (167), Expect = 3e-11
Identities = 55/197 (27%), Positives = 112/197 (56%), Gaps = 31/197 (15%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E+ K A +E++ +E + +R ++R +++++ ++ + + E+++KR E++
Sbjct: 730 EKAKAAKLEQE-----RREAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEE 783
Query: 64 ---KRKKEDKERKKKDEE---KVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQ 112
+RK+E+ R+++++E + + EEE ++++EE E+++ +EEER+KQEE R+
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE-LLRK 842
Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
QEEEAA +E+EE+ Q E + LR E + A R EE R + +++
Sbjct: 843 QEEEAAKWAREEEEA----QRRLEENRLRME-----EEAARLRHEEEERKRKELEVQRQ- 892
Query: 173 AFVKKLKTITEQQRDSL 189
K+L +QQ+++L
Sbjct: 893 ---KELMRQRQQQQEAL 906
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/130 (28%), Positives = 76/130 (58%), Gaps = 6/130 (4%)
Query: 45 AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK- 103
A +++ + + K +LE ++R+ E R K++EE+ K +EE ++++EE ++ QEEERK
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAE--MRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELR---SKNQNAPDSRPEENF 160
++EE+ R+++EEA + +E+E +++ +E ER + LR + + + R +E
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
Query: 161 FSRLDSSLKK 170
+ + K
Sbjct: 840 LRKQEEEAAK 849
Score = 62.0 bits (149), Expect = 3e-09
Identities = 39/141 (27%), Positives = 86/141 (60%), Gaps = 13/141 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E ++ A +++++L +E++ + RR +ER + + L +E + E+++K+ E+
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ-EEL 839
Query: 64 KRKKEDKERK--KKDEEKVKAEEESKKKEEEE--KKKHQEEERKKQEEQA--------KR 111
RK+E++ K +++EE + EE++ + EEE + +H+EEERK++E + +R
Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899
Query: 112 QQEEEAAAQMKEKEESIQLHQ 132
QQ++EA +++++++ QL Q
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQ 920
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 12/118 (10%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSK---APEDKKKRLEDDK-RKK 67
EE+ + ERR + R ++++ ++E +K E+ ++RLE+++ R +
Sbjct: 810 EEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME 869
Query: 68 EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---QQEEEAAAQMK 122
E+ R + +E EE +K+ E +++K +R++Q+E +R QQ+++ AQMK
Sbjct: 870 EEAARLRHEE-----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922
Score = 40.4 bits (93), Expect = 0.011
Identities = 41/216 (18%), Positives = 94/216 (43%), Gaps = 57/216 (26%)
Query: 4 ERKKPASM---EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
ER+K + +E+++ +E++ ++RR ++ R +++ +E E K+K L
Sbjct: 832 ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE----EERKRKEL 887
Query: 61 EDDKRKKEDKERKKKDEEKVKAEE------------------------------------ 84
E ++K+ ++R+++ E + ++
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947
Query: 85 ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK------------EKEESIQLHQ 132
E +K EEE +++ +EE+R++Q E K Q+++ Q K + +++ Q
Sbjct: 948 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007
Query: 133 EAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
E E ++K+ + + Q+ +R N S L +S+
Sbjct: 1008 E--EARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
Score = 32.0 bits (71), Expect = 3.9
Identities = 19/70 (27%), Positives = 32/70 (45%)
Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
D+ T G LE+ ++ E+ A EQ E+E+ EEE ++ ++EE
Sbjct: 715 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 774
Query: 1081 DSNKENETDE 1090
+ K E +E
Sbjct: 775 EERKRREEEE 784
Score = 30.8 bits (68), Expect = 8.6
Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 13/97 (13%)
Query: 1009 IKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAET-----------EEQSGNESEVNEPEE 1057
++ G + D +DS+ E ED EEE G ++ +E E E++
Sbjct: 271 VRSGSGSIDDDRDSLPEW--CLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 328
Query: 1058 EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
+EG + D EG EE T+ + +TD E
Sbjct: 329 DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVE 365
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 70.1 bits (170), Expect = 1e-11
Identities = 43/117 (36%), Positives = 75/117 (64%), Gaps = 6/117 (5%)
Query: 48 EVSKAPEDKKKRLEDDKR-KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEE--RKK 104
E +KA + +++R E + R K+E++ERK+++E + + EE ++++EEE+K+ +EEE R+K
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRK 789
Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRK---ELRSKNQNAPDSRPEE 158
QEE +RQ+E+E A + + +EE Q +EA R R+ E R K + + EE
Sbjct: 790 QEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 846
Score = 68.9 bits (167), Expect = 3e-11
Identities = 55/197 (27%), Positives = 112/197 (56%), Gaps = 31/197 (15%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E+ K A +E++ +E + +R ++R +++++ ++ + + E+++KR E++
Sbjct: 730 EKAKAAKLEQE-----RREAEMRAKREEEERKR-QEELRRQQEEILRRQQEEERKRREEE 783
Query: 64 ---KRKKEDKERKKKDEE---KVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQ 112
+RK+E+ R+++++E + + EEE ++++EE E+++ +EEER+KQEE R+
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE-LLRK 842
Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
QEEEAA +E+EE+ Q E + LR E + A R EE R + +++
Sbjct: 843 QEEEAAKWAREEEEA----QRRLEENRLRME-----EEAARLRHEEEERKRKELEVQRQ- 892
Query: 173 AFVKKLKTITEQQRDSL 189
K+L +QQ+++L
Sbjct: 893 ---KELMRQRQQQQEAL 906
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/130 (28%), Positives = 76/130 (58%), Gaps = 6/130 (4%)
Query: 45 AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK- 103
A +++ + + K +LE ++R+ E R K++EE+ K +EE ++++EE ++ QEEERK
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAE--MRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELR---SKNQNAPDSRPEENF 160
++EE+ R+++EEA + +E+E +++ +E ER + LR + + + R +E
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
Query: 161 FSRLDSSLKK 170
+ + K
Sbjct: 840 LRKQEEEAAK 849
Score = 62.0 bits (149), Expect = 3e-09
Identities = 39/141 (27%), Positives = 86/141 (60%), Gaps = 13/141 (9%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E ++ A +++++L +E++ + RR +ER + + L +E + E+++K+ E+
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ-EEL 839
Query: 64 KRKKEDKERK--KKDEEKVKAEEESKKKEEEE--KKKHQEEERKKQEEQA--------KR 111
RK+E++ K +++EE + EE++ + EEE + +H+EEERK++E + +R
Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899
Query: 112 QQEEEAAAQMKEKEESIQLHQ 132
QQ++EA +++++++ QL Q
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQ 920
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 12/118 (10%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSK---APEDKKKRLEDDK-RKK 67
EE+ + ERR + R ++++ ++E +K E+ ++RLE+++ R +
Sbjct: 810 EEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRME 869
Query: 68 EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR---QQEEEAAAQMK 122
E+ R + +E EE +K+ E +++K +R++Q+E +R QQ+++ AQMK
Sbjct: 870 EEAARLRHEE-----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922
Score = 40.4 bits (93), Expect = 0.011
Identities = 41/216 (18%), Positives = 94/216 (43%), Gaps = 57/216 (26%)
Query: 4 ERKKPASM---EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
ER+K + +E+++ +E++ ++RR ++ R +++ +E E K+K L
Sbjct: 832 ERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE----EERKRKEL 887
Query: 61 EDDKRKKEDKERKKKDEEKVKAEE------------------------------------ 84
E ++K+ ++R+++ E + ++
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947
Query: 85 ESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK------------EKEESIQLHQ 132
E +K EEE +++ +EE+R++Q E K Q+++ Q K + +++ Q
Sbjct: 948 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007
Query: 133 EAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
E E ++K+ + + Q+ +R N S L +S+
Sbjct: 1008 E--EARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
Score = 32.0 bits (71), Expect = 3.9
Identities = 19/70 (27%), Positives = 32/70 (45%)
Query: 1021 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1080
D+ T G LE+ ++ E+ A EQ E+E+ EEE ++ ++EE
Sbjct: 715 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE 774
Query: 1081 DSNKENETDE 1090
+ K E +E
Sbjct: 775 EERKRREEEE 784
Score = 30.8 bits (68), Expect = 8.6
Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 13/97 (13%)
Query: 1009 IKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAET-----------EEQSGNESEVNEPEE 1057
++ G + D +DS+ E ED EEE G ++ +E E E++
Sbjct: 271 VRSGSGSIDDDRDSLPEW--CLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPV 328
Query: 1058 EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
+EG + D EG EE T+ + +TD E
Sbjct: 329 DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVE 365
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 69.7 bits (169), Expect = 2e-11
Identities = 41/198 (20%), Positives = 97/198 (48%), Gaps = 14/198 (7%)
Query: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
A+ + EEK + + ++ ER + +E+ + + K+E +A E++++ E+
Sbjct: 289 ADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEE 348
Query: 63 DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE------- 115
+KR E+++R K++E++ E + + EEEEK K +E++R KQ E+ K +E
Sbjct: 349 EKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEK 408
Query: 116 -------EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSL 168
+ + K +E+ +Q + ++++K + + +P D +
Sbjct: 409 VEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKI 468
Query: 169 KKNTAFVKKLKTITEQQR 186
KK+ +++K+ ++++
Sbjct: 469 KKDKEPKEEVKSFMDRKK 486
Score = 67.8 bits (164), Expect = 6e-11
Identities = 53/199 (26%), Positives = 99/199 (49%), Gaps = 20/199 (10%)
Query: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
AER + + E + +K ER + ++E K A++ + E++++ E+
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEE------KAAAQERERREAEERERMREE 320
Query: 63 DKRKKEDKERKKKDEEKVKAEEESKKKEE-----EEKKKHQEEERKKQEEQAKRQQEEEA 117
+KR E+++R K+EEK AEE + KEE EE+++ +EEE++ EE+ + + EEE
Sbjct: 321 EKRAAEERQR-IKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEE 379
Query: 118 AAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
A+++E++ + QL E+ H +E + K + + + K TA +KK
Sbjct: 380 KAKVEEQKRNKQLE----EKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Query: 178 ----LKTITEQQRDSLSHD 192
T + +R+ L D
Sbjct: 436 QGEEKGTKVQAKREKLQED 454
Score = 63.9 bits (154), Expect = 9e-10
Identities = 41/168 (24%), Positives = 94/168 (55%), Gaps = 6/168 (3%)
Query: 18 PNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDE 77
P +E+ +S E+ +++ K A+ E ++ ++++R++ ++ KK ER + +
Sbjct: 238 PKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEA 297
Query: 78 EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE--KEESIQLHQEAW 135
E+ A +E +++E EE+++ +EEE++ EE+ + ++EE+ AA+ ++ KEE + A
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEE---KRAAE 354
Query: 136 ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITE 183
ER +++E + + +R EE ++++ K+N +K + E
Sbjct: 355 ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ-KRNKQLEEKKHAMQE 401
Score = 63.9 bits (154), Expect = 9e-10
Identities = 45/174 (25%), Positives = 94/174 (54%), Gaps = 16/174 (9%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M E K+ A EE+ + +++ ER+ + +E+ + + K+E +A E++++
Sbjct: 317 MREEEKRAA--EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRAR 374
Query: 61 --EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE---ERKKQEEQAK----R 111
E++K K E+++R K+ EEK A +E+K K E+ ++K + + E+K QE++ + +
Sbjct: 375 AEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLK 434
Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
+Q EE +++ K E +Q + +++ ++ E K D P+E S +D
Sbjct: 435 KQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK-----DKEPKEEVKSFMD 483
Score = 62.0 bits (149), Expect = 3e-09
Identities = 39/152 (25%), Positives = 83/152 (54%), Gaps = 12/152 (7%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKEVSKAPEDKKKRLEDDKRKK 67
MEE+D KE+ +ER + ++ER + + K A + E+K E ++R+
Sbjct: 257 MEEED-----KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREA 311
Query: 68 EDKERKKKDEEKVKAEEESKKKEE----EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
E++ER +++E++ E + K+EE EE+++ +EEE++ EE+ + ++EE+ AA+ ++
Sbjct: 312 EERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 371
Query: 124 KEESIQLHQEAWERHHLRKELRSKNQNAPDSR 155
+ + + + E K+L K +++
Sbjct: 372 RARAEEEEKAKVEEQKRNKQLEEKKHAMQETK 403
Score = 57.4 bits (137), Expect = 9e-08
Identities = 59/239 (24%), Positives = 116/239 (48%), Gaps = 38/239 (15%)
Query: 4 ERKKPASMEEKD---SLPNNKEKDCSERRTVSSKERPKDDIKLTAKK-----EVSKAPED 55
+++K EEK S+ N+ + E +T S+E + + ++ K E K E+
Sbjct: 187 DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQE---ETVVMSLKNGQISSEEPKQEEE 243
Query: 56 KKKRLED----DKRKKEDKER--------KKKDEEKVKAEEESK------KKEEEEKKKH 97
+++ ++ +K ++EDKER + ++ E++KAE++ K + E EEK
Sbjct: 244 REQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAA 303
Query: 98 QEEERKKQEEQAKRQQEEEAAAQMKE--KEESIQLHQEAWERHHLRKELRSKNQNAPDSR 155
QE ER++ EE+ + ++EE+ AA+ ++ KEE + A ER +++E + + +
Sbjct: 304 QERERREAEERERMREEEKRAAEERQRIKEEE---KRAAEERQRIKEEEKRAAEERQRIK 360
Query: 156 PEENFFSRLDSSLKKNTAFVKKLKTITEQQRD-SLSHDFNGLNLSKYIAEAVASIVEAK 213
EE R ++ A ++ + EQ+R+ L + + +K E V +E K
Sbjct: 361 EEE---KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK 416
Score = 57.4 bits (137), Expect = 9e-08
Identities = 46/131 (35%), Positives = 72/131 (54%), Gaps = 15/131 (11%)
Query: 47 KEVSKAPE-DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERK-- 103
KE AP+ + KRLE+ +R++ + E ++ EK+K +++ E EE KK +EE RK
Sbjct: 522 KEAEGAPQVEAGKRLEELRRRRGETE--SEEFEKLKQKQQEAALELEELKKKREERRKVL 579
Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAP-----DSRPEE 158
++EEQ ++Q EEA +++E+EE +L +E R R E K Q P D +
Sbjct: 580 EEEEQRRKQ--EEADRKLREEEEKRRLKEEIERR---RAEAAEKRQKMPEDGLSDDKKPF 634
Query: 159 NFFSRLDSSLK 169
F+ SSLK
Sbjct: 635 KCFTPKGSSLK 645
Score = 55.8 bits (133), Expect = 3e-07
Identities = 59/249 (23%), Positives = 115/249 (46%), Gaps = 38/249 (15%)
Query: 3 AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK-KEVSKAPEDKKKRLE 61
AE ++ EEK + + E+R ++R K++ K A+ ++ ++A E++K ++E
Sbjct: 325 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384
Query: 62 DDKRKKEDKERK----------KKDEEKV--------KAEEES------KKKEEEEKKKH 97
+ KR K+ +E+K +K E+K+ KA+E+ KK+ EE+ K
Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKV 444
Query: 98 QEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQN--APDSR 155
Q + K QE++ ++EE ++K+ +E + + +R E++S+N +
Sbjct: 445 QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 504
Query: 156 PEENFFSRLDSSLKKNTAFV---------KKLKTITEQQRDSLSHDFNGLNLSKYIAEAV 206
EN FSR +T K+L+ + ++ ++ S +F L + EA
Sbjct: 505 HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ--QEAA 562
Query: 207 ASIVEAKLK 215
+ E K K
Sbjct: 563 LELEELKKK 571
Score = 50.8 bits (120), Expect = 8e-06
Identities = 40/172 (23%), Positives = 86/172 (50%), Gaps = 15/172 (8%)
Query: 24 DCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKA- 82
D E E K +L ++ +++ E +K + + + E +E KKK EE+ K
Sbjct: 520 DTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVL 579
Query: 83 --EEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE---- 136
EE+ +K+EE ++K +EEE+++ +E+ +R++ E A + K E+ + ++ ++
Sbjct: 580 EEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTP 639
Query: 137 -----RHHLRKELRSKN---QNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
+ R E +K+ + S + S++DS L++ T+ ++ K+
Sbjct: 640 KGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKS 691
Score = 48.1 bits (113), Expect = 5e-05
Identities = 51/199 (25%), Positives = 90/199 (45%), Gaps = 45/199 (22%)
Query: 4 ERKK---PASMEEKDSLPNNK-EKDCSERRTVSSKERPK---DDIKLTAKKEVSKAPEDK 56
ER+K P + SLP+ + + D +E T +E+ + + ++ + V+K+ +
Sbjct: 116 ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKN 175
Query: 57 KKRLEDDKRKKEDKERKKKDEEKVK------------AEEESKKKEEE------------ 92
R + ++ KKEDKE+++++EEK K EE++ + +EE
Sbjct: 176 DWR-DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQIS 234
Query: 93 EKKKHQEEERK----------KQEEQAKRQQEEEAAAQMKEKEESIQLHQE---AWERHH 139
++ QEEER+ K EE+ K + E E A E+ E I+ Q+ A ER
Sbjct: 235 SEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERAR 294
Query: 140 LRKELRSKNQNAPDSRPEE 158
+ E ++ Q EE
Sbjct: 295 IEAEEKAAAQERERREAEE 313
Score = 42.4 bits (98), Expect = 0.003
Identities = 17/66 (25%), Positives = 46/66 (69%), Gaps = 1/66 (1%)
Query: 62 DDKRKKEDKERKKKDEEKVKAEEES-KKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
DD ++ + R+K++E +++AE + ++ +++E++ +E R+ ++E+ +++QEEE+ Q
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 121 MKEKEE 126
+ ++ E
Sbjct: 62 VTDQVE 67
Score = 38.9 bits (89), Expect = 0.032
Identities = 37/166 (22%), Positives = 80/166 (48%), Gaps = 12/166 (7%)
Query: 24 DCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAE 83
D RR + ++R ++++L A++ + +D ++ ++R++ +ER ++ +E+
Sbjct: 3 DFERRRELRRQKR--EEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 84 EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA--AQMKEKEESIQLH-QEAWERHHL 140
+ + + E + +EE K + + ++EAA ++ +EE Q QEA ER
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALER--- 117
Query: 141 RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
+KE +A S P R+ + +N K+ K+ + Q+R
Sbjct: 118 QKEFDPTITDASLSLPSR----RMQNDTAENETTEKEEKSESRQER 159
Score = 38.1 bits (87), Expect = 0.054
Identities = 49/242 (20%), Positives = 96/242 (39%), Gaps = 37/242 (15%)
Query: 1019 SKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE----- 1073
+++ TE E E +E ETE + + + + + EE D ++ EEEEE
Sbjct: 142 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201
Query: 1074 ---ENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMM-LENLQQRS 1129
EN + K E+ EE + +K G + ++E+ Q D++ E +++
Sbjct: 202 SIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261
Query: 1130 GESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVP 1189
E + + + EAE + + + K + +
Sbjct: 262 KERAEAERARL---------------------EAEERERIK----AEQDKKIADERARIE 296
Query: 1190 MSSQLAANHWNQQQAEQEERMR-MKKLTLDINERQEQEDYQ--EMLQSLAQRPAPANTNR 1246
+ AA +++AE+ ERMR +K + +R ++E+ + E Q + + A R
Sbjct: 297 AEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 356
Query: 1247 ER 1248
+R
Sbjct: 357 QR 358
Score = 37.4 bits (85), Expect = 0.092
Identities = 38/193 (19%), Positives = 80/193 (41%), Gaps = 22/193 (11%)
Query: 19 NNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEE 78
+++E+ ERR + +ER + + + +V+ E + D+ K + + +
Sbjct: 32 DDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGD 91
Query: 79 KVKAEEESKKKEEEEKKKHQEEERKKQEE------------QAKRQQEEEAAAQMKEKEE 126
A E + EE ++K +E ++Q+E ++R Q + A + EKEE
Sbjct: 92 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEE 151
Query: 127 SIQLHQEAWE--------RHHLRKELRSKNQNAPD--SRPEENFFSRLDSSLKKNTAFVK 176
+ QE +E + + + + R +N + + EE S+ +N V
Sbjct: 152 KSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVM 211
Query: 177 KLKTITEQQRDSL 189
+ TE Q +++
Sbjct: 212 VEEKTTESQEETV 224
Score = 35.0 bits (79), Expect = 0.46
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 12/103 (11%)
Query: 1004 EREFLIKLGLVND-KDSKDSMTEGENLEEDEEEE-EGGAETEEQSGNESEVNEPEEEEGS 1061
E E + K ND +D++++ E + EE+EEE+ + G+ E Q E E +E +
Sbjct: 164 ETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEET 223
Query: 1062 ----------DNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
+++ + EEE E+ +D ++ K E D+E E
Sbjct: 224 VVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266
Score = 32.0 bits (71), Expect = 3.9
Identities = 42/238 (17%), Positives = 91/238 (38%), Gaps = 12/238 (5%)
Query: 1020 KDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYL 1079
K+ E +++EE E+G E E E E E E + + +E E + E +
Sbjct: 229 KNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI 288
Query: 1080 TDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLD 1139
D E +E+ + + + +E+ A ++ ++ ++R+ E + + +
Sbjct: 289 ADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEE 348
Query: 1140 VAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQL-AANH 1198
+ +++ E E +A+ R +++ K+ + QL H
Sbjct: 349 EKRAAEERQRIK--------EEEKRAAEER---QRARAEEEEKAKVEEQKRNKQLEEKKH 397
Query: 1199 WNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPK 1256
Q+ + E++ K +NE++ QED + Q + +R + Q K
Sbjct: 398 AMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDK 455
Score = 30.8 bits (68), Expect = 8.6
Identities = 25/103 (24%), Positives = 43/103 (41%), Gaps = 4/103 (3%)
Query: 460 EDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLE 519
E+ + E L K F P I D S ++ D + KE K S +
Sbjct: 104 EERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAENETTEKEEKSESRQE--R 159
Query: 520 LELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGS 562
E+E E + + +AE+ K+ +++E+E+E+ GS
Sbjct: 160 YEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 202
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 68.6 bits (166), Expect = 4e-11
Identities = 39/138 (28%), Positives = 83/138 (60%), Gaps = 11/138 (7%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ + E++ + +E+ E+ +E+ ++ K+ ++E + E+K + ++
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQ-----EEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 65 RKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAA 118
R++E+K E K +++E++ E+E K E+EEK QEE+ ++QEE+ +RQ+E+ E
Sbjct: 588 REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 647
Query: 119 AQMKEKEESIQLHQEAWE 136
+++++EE +Q HQE E
Sbjct: 648 VRLRQQEEKMQEHQEHLE 665
Score = 63.9 bits (154), Expect = 9e-10
Identities = 47/181 (25%), Positives = 101/181 (55%), Gaps = 22/181 (12%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK- 70
E+++ + +EK + + KE K+ ++E+ E+K +RLE+ +KE+K
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEE-----KMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
Query: 71 -ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI- 128
E ++K E+ K E+ +K++EEEK + QE K+QE++AK ++EE +++E+EE I
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWRQEE---KIREQEEKIR 433
Query: 129 QLHQEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
+ ++ W E+ H ++++R + + R E+ R + +++ ++ + + EQ+
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREE-----EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQE 488
Query: 186 R 186
+
Sbjct: 489 K 489
Score = 62.4 bits (150), Expect = 3e-09
Identities = 46/167 (27%), Positives = 89/167 (53%), Gaps = 13/167 (7%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E++K EEK K D E+ ++ + + K+ ++E + E+K + E+
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
Query: 64 KRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
+++E+K E K +++EK++ +EE K +E+EEK + Q+E+ ++QEE+ Q+E
Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEE-KIREQEEKIREQKEKIREQEEKIWEQEE----- 599
Query: 120 QMKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDS--RPEENFFSR 163
+++E+EE +Q +E WE+ E K Q + R EE + +
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646
Score = 62.0 bits (149), Expect = 3e-09
Identities = 49/177 (27%), Positives = 95/177 (53%), Gaps = 20/177 (11%)
Query: 22 EKDCSERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKKEDKERKK----- 74
EK+ RR ++ I+ +K E K E ++KR E++K ++++K +++
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419
Query: 75 KDEEKVKAEEESKKKEEEEKKKHQEE---ERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
+ EEK++ E+E K +E+E+K QEE E++K E+ KRQ++EE M +EE I+
Sbjct: 420 RQEEKIR-EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIREQ 474
Query: 132 QEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
+E W E+ H ++++R + + R EE + + ++ ++ + I EQ+
Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKV--WRQEEKMHDQEEKIREQEEKMWRQEEKIREQE 529
Score = 60.8 bits (146), Expect = 8e-09
Identities = 43/187 (22%), Positives = 97/187 (51%), Gaps = 14/187 (7%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE--D 62
R++ E+++ + ++K + + +E+ +++ K ++E+ + E +++ E
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 63 DKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
K K ++E+ +K EEKV +EE K ++EEK + QEE+ +QEE+ R+QEE +++
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEE-KMHDQEEKIREQEEKMWRQEEKI-REQEE----KIR 533
Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTIT 182
E+EE I+ E+ + +E K + E+ R + +++ +++ K
Sbjct: 534 EQEEKIR------EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 183 EQQRDSL 189
+Q + +
Sbjct: 588 REQEEKI 594
Score = 60.5 bits (145), Expect = 1e-08
Identities = 43/196 (21%), Positives = 100/196 (51%), Gaps = 17/196 (8%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPED----KKKRL 60
R++ + E++ +E+ E+ + +E+ ++ ++ ++E + E+ K+K
Sbjct: 426 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMH 485
Query: 61 EDDK-RKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE- 114
E +K RK+E+K E K D+E+ E+E K +EEK + QEE+ ++QEE+ + Q+E
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
Query: 115 -EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTA 173
+E +M E+EE +Q E+ +R++ + R ++ + + +
Sbjct: 546 MQEQEEKMGEQEEKMQ------EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 174 FVKKLKTITEQQRDSL 189
+++ + + ++Q + +
Sbjct: 600 KIREQEEMMQEQEEKM 615
Score = 58.2 bits (139), Expect = 5e-08
Identities = 42/160 (26%), Positives = 85/160 (53%), Gaps = 13/160 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK- 70
+E++ + +EK + KE+ + K+ ++E E+K E+ R++E+K
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
Query: 71 ----ERKKKDEEKVKAEEES-KKKEE---EEKKKHQEEERKKQEEQAKRQQEE---EAAA 119
E+ ++ EEK++ +EE +++EE E+++K E+E K QE++ R+QEE E
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
Query: 120 QMKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDSRPEE 158
+++E++E I+ +E WE+ +E Q + E+
Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618
Score = 57.4 bits (137), Expect = 9e-08
Identities = 40/131 (30%), Positives = 71/131 (54%), Gaps = 12/131 (9%)
Query: 34 KERPKDDIKLTAKKEVSKA-----PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
KE KL A+ E ++ + ++K +++ +E +E+ ++ EEK++ E+E K
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-EQEEKI 330
Query: 89 KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESI-QLHQEAWERHHLRKELRSK 147
+E+EEK + QEE ++EE+ +RQ+E M EKEE + +L + WE+ +EL K
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEE-----MMWEKEEKMRRLEEMMWEKEEKIRELEEK 385
Query: 148 NQNAPDSRPEE 158
R +E
Sbjct: 386 MHEQEKIREQE 396
Score = 54.7 bits (130), Expect = 6e-07
Identities = 32/160 (20%), Positives = 89/160 (55%), Gaps = 15/160 (9%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDK----KK 58
R++ ++++ + +EK + + +E + + K+ ++E+ + E+K ++
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558
Query: 59 RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEE----EKKKHQEEERKKQEEQAKRQQE 114
++++ ++ + +E+ ++ EEK++ ++E +++EE +++K +E+E QE++ K ++
Sbjct: 559 KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618
Query: 115 EEAAAQ----MKEKEESIQLHQE-AWERHHLRKELRSKNQ 149
EE + M+E+EE ++ +E WE+ ++ K Q
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Score = 54.3 bits (129), Expect = 7e-07
Identities = 47/221 (21%), Positives = 108/221 (48%), Gaps = 11/221 (4%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R+ M EK+ E+ E+ + +E + + + ++E + E K R E+
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAKRQQEE--EAAAQ 120
R++E+K R++ E+K+ +EE ++E+ E++K QE+E ++E+ R+QEE +
Sbjct: 426 REQEEKIREQ--EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 121 MKEKEESIQLHQEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
M E+E+ + ++ W E+ H ++E + + Q R EE + + +++ +++
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEE-KIREQEEKMWRQEEKIREQ-EEKIREQEEKIRE 541
Query: 178 LKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISD 218
+ + ++Q + + + + + I E + KI +
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIRE 582
Score = 54.3 bits (129), Expect = 7e-07
Identities = 31/129 (24%), Positives = 69/129 (53%), Gaps = 5/129 (3%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ M+E++ +E+ E+ + +E + + +++ K E ++K E ++
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 65 RKKEDKERKKKDEEKVKAEEES-----KKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAA 119
+ +E +E ++ EEK+ +EE +K +E+E+K ++EE+ ++E RQQEE+
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Query: 120 QMKEKEESI 128
+ E +I
Sbjct: 660 HQEHLEAAI 668
Score = 53.1 bits (126), Expect = 2e-06
Identities = 36/149 (24%), Positives = 78/149 (52%), Gaps = 10/149 (6%)
Query: 47 KEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE 106
++ K E ++K E +++ +E +E+ ++ EEK++ +EE E+EEK + QEE ++E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW-EKEEKMRRQEEMMWEKE 362
Query: 107 EQAKRQQE---------EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPE 157
E+ +R +E E +M E+E+ + ++ E +R++ + + Q A R E
Sbjct: 363 EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 158 ENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
E + + ++ ++ + I EQ++
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEK 451
Score = 47.0 bits (110), Expect = 1e-04
Identities = 38/151 (25%), Positives = 73/151 (48%), Gaps = 13/151 (8%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-------- 56
++K A ++EK L +++ + + V +R + KL ++ +A D
Sbjct: 220 KEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 57 KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE- 115
+L+ + E R + +E+ +E K +E EEK + QEE+ ++QEE+ + Q+E+
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 116 -EAAAQMKEKEESIQLHQE-AWERHHLRKEL 144
M EKEE ++ +E WE+ + L
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRL 368
Score = 42.7 bits (99), Expect = 0.002
Identities = 41/174 (23%), Positives = 79/174 (45%), Gaps = 13/174 (7%)
Query: 21 KEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK------KKRLEDDKRKKEDKERKK 74
KEK+ + + E K +I+L K+ K K + + E D KE +
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 75 KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEA 134
K + +V+ E + +++++K +E K QE + K Q++EE +++E+EE I+ +E
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE---KIREQEEKIREQEEK 336
Query: 135 WERHH---LRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
R KE + + Q EE RL+ + + +++L+ +Q
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEK-MRRLEEMMWEKEEKIRELEEKMHEQ 389
Score = 35.0 bits (79), Expect = 0.46
Identities = 28/119 (23%), Positives = 55/119 (46%), Gaps = 8/119 (6%)
Query: 981 ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEE---EEE 1037
E +R + + EE IR+ +++ +E K+G + ++ M E E + EE E+E
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMG-----EQEEKMQEQEKMRRQEEKIREQE 577
Query: 1038 GGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVM 1096
+++ E E E+EE ++ +E+EE+ + ++ E +E E M
Sbjct: 578 EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636
Score = 33.1 bits (74), Expect = 1.7
Identities = 50/262 (19%), Positives = 111/262 (42%), Gaps = 36/262 (13%)
Query: 975 MISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEE 1034
M+ + E +R + ++ EE +R+++++ E K+ ++ ++ M E E + E EE
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI-----RELEEKMHEQEKIREQEE 397
Query: 1035 ---EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEE---EENTDYLTDSNKENET 1088
EEE E E++ E+++ EE+ + +E++ +E + + +E E
Sbjct: 398 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457
Query: 1089 DEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESV-----KVHQLDVAIP 1143
+E E+ + ++ E E+ + +KM + ++ E V K+H + I
Sbjct: 458 RQEQEEMWRQEEKIR-----EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR 512
Query: 1144 LHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQ 1203
+ R+ + E K +Q+ KI Q +Q+
Sbjct: 513 EQEEKMWRQEEKIREQE---------------EKIREQEEKIREQEEMMQEQEEKMGEQE 557
Query: 1204 AEQEERMRMKKLTLDINERQEQ 1225
+ +E+ +M++ I E++E+
Sbjct: 558 EKMQEQEKMRRQEEKIREQEEK 579
Score = 32.7 bits (73), Expect = 2.3
Identities = 29/129 (22%), Positives = 65/129 (50%), Gaps = 16/129 (12%)
Query: 21 KEKDCSE----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
KE+D R T++ +E + + KL K ++ ++ + + + + ++K ++ +
Sbjct: 200 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 259
Query: 77 EEKVKAEEESKKKEEEE---KKKHQEEE-----RKKQEEQAKRQQEEEAAAQMKEK---- 124
+++++AE + KE + K + Q EE R Q+++ K ++EE + +EK
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 125 EESIQLHQE 133
EE I+ +E
Sbjct: 320 EEKIREQEE 328
Score = 32.0 bits (71), Expect = 3.9
Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 21/190 (11%)
Query: 956 KKSLEVWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVN 1015
K+ +VW ++ + D E +R + + EE IR+ ++ RE K+
Sbjct: 492 KQEEKVWRQEEK--------MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI---- 539
Query: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEEN 1075
++ ++ M E E E+ E+EE E E+ E ++ E+EE ++ E+EE+
Sbjct: 540 -REQEEMMQEQE--EKMGEQEEKMQEQEKMRRQEEKIR--EQEEKIREQKEKIREQEEKI 594
Query: 1076 TDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKV 1135
+ ++ E +E E M + + E E+ +Q ++ M ++ + V++
Sbjct: 595 WEQEEKIREQEEMMQEQEEKMWE----QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 650
Query: 1136 HQLDVAIPLH 1145
Q + + H
Sbjct: 651 RQQEEKMQEH 660
Score = 31.2 bits (69), Expect = 6.6
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 7/109 (6%)
Query: 64 KRKKEDK--ERKKKDEEKVKAE-EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
++KK D+ E K+ + + E + +EE K+K+ + + K Q ++++ + + +
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 121 MKEKEESIQL----HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
+K K E +L Q E HL KEL+S + E ++RL+
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Score = 31.2 bits (69), Expect = 6.6
Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 14/115 (12%)
Query: 994 EESIRQVQDLEREFLIKLG----LVNDKDSKDSMTEGENLEEDE----------EEEEGG 1039
EE IR+ ++ RE K+ ++ +K+ K E E++E E+EE
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
Query: 1040 AETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
E EE+ + ++ E EE+ + E E+ +E+ K E +E+ E
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 68.6 bits (166), Expect = 4e-11
Identities = 46/205 (22%), Positives = 96/205 (46%), Gaps = 25/205 (12%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M E+KK +E+K + + K + E R K + K K + E + E++ +RL
Sbjct: 591 MKEEKKK--QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 648
Query: 61 -----EDDKRKKEDKERKKKDEEKVK----------AEEESKKKEEEEKKKHQEEERKKQ 105
E+++R+ ++ +KKK+EE+ + AE+ +++ E+E+++ + E++++
Sbjct: 649 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR 708
Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWER--------HHLRKELRSKNQNAPDSRPE 157
E++ + Q+ + A + + ++E +Q +E ER L++EL K + R
Sbjct: 709 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 768
Query: 158 ENFFSRLDSSLKKNTAFVKKLKTIT 182
E K A K +T
Sbjct: 769 ERQLQEEQEKKAKEAAGASKALNVT 793
Score = 64.3 bits (155), Expect = 7e-10
Identities = 52/185 (28%), Positives = 92/185 (49%), Gaps = 13/185 (7%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIK--LTAKKEVSKAPEDKKKRLEDDKRKKED 69
EE + L K ++ RR K + ++ ++ L A++ V + E+KKK++E + ++
Sbjct: 549 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 608
Query: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR-----QQEEEAAAQ---M 121
K K K+E AEE++KKK KK + E R+KQEE+A+R Q+EEE Q
Sbjct: 609 KTEKAKEERL--AEEKAKKK-AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 665
Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
K+KEE + ++A E L ++ + + E R + ++ + + +
Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 725
Query: 182 TEQQR 186
EQ+R
Sbjct: 726 REQER 730
Score = 62.4 bits (150), Expect = 3e-09
Identities = 42/165 (25%), Positives = 84/165 (50%), Gaps = 5/165 (3%)
Query: 26 SERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD-EEKVKAEE 84
+ R KE K I+ + K + K++RL ++K KK+ +K ++ E + K EE
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643
Query: 85 ESKK----KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHL 140
E+++ ++EEE+++HQE +KK+EE+ +R ++ A ++ E+ E + QE E+
Sbjct: 644 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703
Query: 141 RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
+E R + + + + E R L+ ++ K + Q+
Sbjct: 704 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 748
Score = 58.2 bits (139), Expect = 5e-08
Identities = 57/208 (27%), Positives = 98/208 (47%), Gaps = 39/208 (18%)
Query: 14 KDSLPNNKEKDCS----ERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED 69
K + P + CS ER+ + + R ++ +L +K EDK++RLE+ K K+E+
Sbjct: 521 KRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQK----VEEDKRRRLEEVKLKREE 576
Query: 70 KERK----------KKDEEKVKAEEE--------SKKKEE---EEKKKHQEEERKKQEEQ 108
+ RK K+E+K + E++ K KEE EEK K + +K +E +
Sbjct: 577 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636
Query: 109 AKRQQEEEA-AAQMKEKEESIQLHQEAW------ERHHLRKELRSK---NQNAPDSRPEE 158
A+R+QEEEA + ++EE + HQE E+ LRK +K Q + R +E
Sbjct: 637 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 696
Query: 159 NFFSRLDSSLKKNTAFVKKLKTITEQQR 186
++ ++ + + EQ+R
Sbjct: 697 RREQERREQERREQERREQERQLAEQER 724
Score = 45.8 bits (107), Expect = 3e-04
Identities = 36/165 (21%), Positives = 85/165 (51%), Gaps = 11/165 (6%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
ER + A+ ++ + +E+ ERR +ER + + + ++E + ++++R E +
Sbjct: 673 ERLRKAAEAKRLAEQREQERREQERR---EQERREQERREQERREQERQLAEQERRREQE 729
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE--ERKKQEEQAKRQQEEEAAAQM 121
+ + E + ++++ +++ E+ ++ EE++KK+ Q+ ER+ QEEQ K+ +EAA
Sbjct: 730 RLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK--AKEAAGAS 787
Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDS 166
K ++ + A + ++ + AP +N+ L+S
Sbjct: 788 KALNVTVDVQSPACTSY----QMTPQGHRAPPKINPDNYGMDLNS 828
Score = 40.4 bits (93), Expect = 0.011
Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 3/118 (2%)
Query: 37 PKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK 96
P+ +K K+ + K +E ++++ E+ RK++ E+ + + E K+ E+ K
Sbjct: 512 PRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVK 571
Query: 97 HQEEERKKQEEQAK---RQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNA 151
+ EER ++ QA+ Q +EE Q+++K I E + L +E K A
Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAA 629
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 68.6 bits (166), Expect = 4e-11
Identities = 46/205 (22%), Positives = 96/205 (46%), Gaps = 25/205 (12%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
M E+KK +E+K + + K + E R K + K K + E + E++ +RL
Sbjct: 587 MKEEKKK--QIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Query: 61 -----EDDKRKKEDKERKKKDEEKVK----------AEEESKKKEEEEKKKHQEEERKKQ 105
E+++R+ ++ +KKK+EE+ + AE+ +++ E+E+++ + E++++
Sbjct: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR 704
Query: 106 EEQAKRQQEEEAAAQMKEKEESIQLHQEAWER--------HHLRKELRSKNQNAPDSRPE 157
E++ + Q+ + A + + ++E +Q +E ER L++EL K + R
Sbjct: 705 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764
Query: 158 ENFFSRLDSSLKKNTAFVKKLKTIT 182
E K A K +T
Sbjct: 765 ERQLQEEQEKKAKEAAGASKALNVT 789
Score = 64.3 bits (155), Expect = 7e-10
Identities = 52/185 (28%), Positives = 92/185 (49%), Gaps = 13/185 (7%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIK--LTAKKEVSKAPEDKKKRLEDDKRKKED 69
EE + L K ++ RR K + ++ ++ L A++ V + E+KKK++E + ++
Sbjct: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 604
Query: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKR-----QQEEEAAAQ---M 121
K K K+E AEE++KKK KK + E R+KQEE+A+R Q+EEE Q
Sbjct: 605 KTEKAKEERL--AEEKAKKK-AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQ 661
Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTI 181
K+KEE + ++A E L ++ + + E R + ++ + + +
Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
Query: 182 TEQQR 186
EQ+R
Sbjct: 722 REQER 726
Score = 62.4 bits (150), Expect = 3e-09
Identities = 42/165 (25%), Positives = 84/165 (50%), Gaps = 5/165 (3%)
Query: 26 SERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD-EEKVKAEE 84
+ R KE K I+ + K + K++RL ++K KK+ +K ++ E + K EE
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 85 ESKK----KEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHL 140
E+++ ++EEE+++HQE +KK+EE+ +R ++ A ++ E+ E + QE E+
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 699
Query: 141 RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
+E R + + + + E R L+ ++ K + Q+
Sbjct: 700 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744
Score = 60.1 bits (144), Expect = 1e-08
Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 25/163 (15%)
Query: 16 SLPNNKEKDCSERRT---VSSKERPKDDIKLTAKKEVS------KAPEDKKKRLEDDKRK 66
S P + K +R T + KE+ + ++ +KE + K EDK++RLE+ K K
Sbjct: 510 SAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK 569
Query: 67 KEDKERKK-KDEEKVKAEEESKKKEEEEK------KKHQEEERKKQEEQAKRQ----QEE 115
+E++ RK + E+V+ +E KKK+ E+K K + +E + EE+AK++ + E
Sbjct: 570 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629
Query: 116 EAAAQMKEKEESIQLH---QEAWERHHLRKELRSKNQNAPDSR 155
E A+ K++EE+ +L QE ER H +EL K + R
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRH--QELLQKKKEEEQER 670
Score = 45.8 bits (107), Expect = 3e-04
Identities = 36/165 (21%), Positives = 85/165 (51%), Gaps = 11/165 (6%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
ER + A+ ++ + +E+ ERR +ER + + + ++E + ++++R E +
Sbjct: 669 ERLRKAAEAKRLAEQREQERREQERR---EQERREQERREQERREQERQLAEQERRREQE 725
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE--ERKKQEEQAKRQQEEEAAAQM 121
+ + E + ++++ +++ E+ ++ EE++KK+ Q+ ER+ QEEQ K+ +EAA
Sbjct: 726 RLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK--AKEAAGAS 783
Query: 122 KEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDS 166
K ++ + A + ++ + AP +N+ L+S
Sbjct: 784 KALNVTVDVQSPACTSY----QMTPQGHRAPPKINPDNYGMDLNS 824
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 67.4 bits (163), Expect = 8e-11
Identities = 46/197 (23%), Positives = 99/197 (50%), Gaps = 16/197 (8%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ M EK+ E+ E+ + +E + + + ++E + E K R E+
Sbjct: 333 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 392
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMK 122
R++E+K R ++E++ E+E K E+EEK QEEE ++QEE+ +RQ+E+ E +++
Sbjct: 393 REQEEKIR---EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 123 EKEESIQLHQEAWERHH----------LRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
E+EE I+ +E + +E + + Q R EE + + +++
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ-EKKIREQE 508
Query: 173 AFVKKLKTITEQQRDSL 189
+++ + + ++Q + +
Sbjct: 509 EKIREQEEMMQEQEEKM 525
Score = 65.1 bits (157), Expect = 4e-10
Identities = 35/132 (26%), Positives = 75/132 (56%), Gaps = 3/132 (2%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
E+++ + +EK + + + +E + + +++ K E + K E + + +E +E
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQMKEKEESIQ 129
+ ++ EEK++ E+E K +E+EEK + QEE ++QEE+ Q+E+ E +M+E+EE ++
Sbjct: 489 KMRRQEEKIR-EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547
Query: 130 LHQEAWERHHLR 141
+E +R
Sbjct: 548 RQEEKMREQEVR 559
Score = 63.5 bits (153), Expect = 1e-09
Identities = 41/156 (26%), Positives = 83/156 (53%), Gaps = 14/156 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
E+++ + +EK + + +E + + +++ K E +KK E +++ +E +E
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Query: 72 RKKKDEEKV------KAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKE 125
++ EEK+ E+E+K +E+EEK + QEE+ ++QE++ + Q+E +++E+E
Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE-----KIREQE 515
Query: 126 ESIQLHQE-AWERHHLRKELRSKNQNAPDS--RPEE 158
E +Q +E WE+ E K Q + R EE
Sbjct: 516 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Score = 63.2 bits (152), Expect = 2e-09
Identities = 37/136 (27%), Positives = 78/136 (57%), Gaps = 9/136 (6%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKEVSKAPEDKKKRLE 61
R++ + E++ +E+ E+ + ++ K + K+ ++ + E+K +R E
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494
Query: 62 DDKRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE-- 115
+ R++E K E K +++E++ E+E K E+EEK QEE+ ++QEE+ +RQ+E+
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Query: 116 EAAAQMKEKEESIQLH 131
E +++++EE +Q H
Sbjct: 555 EQEVRLRQQEEKMQEH 570
Score = 62.0 bits (149), Expect = 3e-09
Identities = 45/189 (23%), Positives = 99/189 (52%), Gaps = 17/189 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK- 70
EEK K ++ E+ ++ + + K+ ++E+ E+K +R E+ +KE+K
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 71 ---ERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAK-RQQEEEAAAQ---M 121
E K ++EK++ +EE +++EE+ E++K QE+E K ++ K R+QEE+ Q M
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406
Query: 122 KEKEESI-QLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
+E+EE + + ++ WE+ +E K R +E + +++ +++ +
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEK------MRRQEEKIREQEKKIREQEEKIREQEE 460
Query: 181 ITEQQRDSL 189
+ ++Q + +
Sbjct: 461 MMQEQEEKM 469
Score = 60.1 bits (144), Expect = 1e-08
Identities = 40/198 (20%), Positives = 100/198 (50%), Gaps = 12/198 (6%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+ +K EEK K ++ E+ + + + K+ ++E+ E+K + LE+
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 64 KRKKE---DKERKKKDEEKVKAEEESKKKE----EEEKKKHQEEERKKQEEQAKRQQEEE 116
++E ++E K+++EEK++ +E+ +++E +E+K ++EE+ +++E+ ++QEE+
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 117 AAAQ---MKEKEESIQLHQEAWERHH--LRKELRSKNQNAPDSRPEENFFSRLDSSLKKN 171
Q M E+EE +Q +E R +R++ + + R +E + + +
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Query: 172 TAFVKKLKTITEQQRDSL 189
+ + + ++Q + +
Sbjct: 473 EGKMCEQEAKMQEQEEKM 490
Score = 59.7 bits (143), Expect = 2e-08
Identities = 40/177 (22%), Positives = 92/177 (51%), Gaps = 7/177 (3%)
Query: 13 EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKER 72
E++ L N + E+ ++ + + K+ ++E + E+K +R E+ +KE+K R
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333
Query: 73 KKKD---EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129
++++ E++ K E +K E+EK + QEE+R+++E+ ++++ +E A+M +EE I+
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 393
Query: 130 LHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
+E +E + Q EE + + + ++ ++ + I EQ++
Sbjct: 394 EQEEKIR----EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446
Score = 54.3 bits (129), Expect = 7e-07
Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 16/163 (9%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-------- 56
++K A ++EK L +++ + + V +R + KL ++ +A D
Sbjct: 208 KEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 265
Query: 57 KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE 116
+L+ + E R + +E+ +E K +E EEK + QEE+ ++QEE+ +RQ+E
Sbjct: 266 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEE-- 323
Query: 117 AAAQMKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDSRPEE 158
M EKEE ++ +E WE+ +EL K R +E
Sbjct: 324 ---MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 363
Score = 53.5 bits (127), Expect = 1e-06
Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 8/125 (6%)
Query: 34 KERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEE 93
KE KL A+ E ++ ++ E+ ++E+K +++ EEK++ E+E K +E+EE
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQER--EEKIQ-EQEEKIREQEE 316
Query: 94 KKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPD 153
K + QEE ++EE+ +RQ+E M EKEE I+ +E +E K Q
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEE-----MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 371
Query: 154 SRPEE 158
R +E
Sbjct: 372 IREQE 376
Score = 35.4 bits (80), Expect = 0.35
Identities = 35/156 (22%), Positives = 69/156 (44%), Gaps = 22/156 (14%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDK--DSKDSMTEGENL-----EEDEEEEEGGAETEEQS 1046
EE IR+ +++ +E K+G +K + ++ M E E E+ E+E+ E EE+
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455
Query: 1047 GNESEVNEPEEE-----EGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGG 1101
+ E+ + +EE EG + + +E+EE + +E E E I+
Sbjct: 456 REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIR--- 512
Query: 1102 LKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQ 1137
E E+ +Q ++ M E ++ + K+ +
Sbjct: 513 -------EQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Score = 35.0 bits (79), Expect = 0.46
Identities = 56/274 (20%), Positives = 109/274 (39%), Gaps = 42/274 (15%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEE-----EEGGAETEEQSGN 1048
EE I++ ++ RE K+ + ++ M E E +EE EE E EE+
Sbjct: 301 EEKIQEQEEKIREQEEKM-----RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 355
Query: 1049 ESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDE---ENTEVMIKGG---GL 1102
+ ++ E EE+ + E E+ +E+ K E +E E E+M + G
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415
Query: 1103 KHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEG- 1161
+ E E+ +Q ++ M ++ + K+ + + I + + +G EG
Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGK 475
Query: 1162 ----EAESADTMPFVMLTRKGNKQQFKIL---------NVPMSSQLAANHWNQQQ----- 1203
EA+ + + + ++Q K + M + W Q++
Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 535
Query: 1204 ----AEQEERMRMKKLTL---DINERQEQEDYQE 1230
EQEE+MR ++ + ++ RQ++E QE
Sbjct: 536 EEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 34.3 bits (77), Expect = 0.78
Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 2/113 (1%)
Query: 981 ELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGA 1040
E +R + K EE IR+ +++ +E K+G K + E E+ +EE
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 1041 ETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE--ENTDYLTDSNKENETDEE 1091
E E++ + E +EE + ++ E+EE+ E + + + ++ EE
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Score = 33.9 bits (76), Expect = 1.0
Identities = 30/133 (22%), Positives = 66/133 (49%), Gaps = 16/133 (12%)
Query: 21 KEKDCSE----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
KE+D R T++ +E + + KL K ++ ++ + + + + ++K ++ +
Sbjct: 188 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 247
Query: 77 EEKVKAEEESKKKEEEE---KKKHQEEE-----RKKQEEQAKRQQEEEAAAQMKEK---- 124
+++++AE + KE + K + Q EE R Q+++ K ++EE + +EK
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307
Query: 125 EESIQLHQEAWER 137
EE I+ +E R
Sbjct: 308 EEKIREQEEKMRR 320
Score = 33.1 bits (74), Expect = 1.7
Identities = 34/176 (19%), Positives = 75/176 (42%), Gaps = 10/176 (5%)
Query: 976 ISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEE 1035
I + E+++ + + EE + + ++ +E K+ +K + E E+ E+
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Query: 1036 EEGGAETEEQSGN------ESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETD 1089
EE E EE+ G E E E+EE +++ E+E++ + ++ E
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 1090 EENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLH 1145
+E E M + + E E+ +Q ++ M ++ + V++ Q + + H
Sbjct: 519 QEQEEKMWE----QEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 31.2 bits (69), Expect = 6.6
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 7/109 (6%)
Query: 64 KRKKEDK--ERKKKDEEKVKAE-EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
++KK D+ E K+ + + E + +EE K+K+ + + K Q ++++ + + +
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234
Query: 121 MKEKEESIQL----HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
+K K E +L Q E HL KEL+S + E ++RL+
Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 283
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 67.0 bits (162), Expect = 1e-10
Identities = 42/150 (28%), Positives = 85/150 (56%), Gaps = 9/150 (6%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
++ + E++ + +EK + + ++R + + K+ ++E + E+K R E+ R
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 66 KKEDKERKK-----KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAA 118
++E+K +++ K EEK++ E+E K +E+EEK + QEE+ ++QEE + Q+E+ E
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIR-EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653
Query: 119 AQMKEKEESIQLHQEA-WERHHLRKELRSK 147
+M E+EE +Q +E W + +E K
Sbjct: 654 EKMCEQEEKMQEQEETMWRQEEKIREQEKK 683
Score = 63.9 bits (154), Expect = 9e-10
Identities = 43/149 (28%), Positives = 84/149 (56%), Gaps = 6/149 (4%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+ +K EEK K ++ E + +E+ ++ ++T ++E K E ++K E +
Sbjct: 603 QEEKMWKQEEKIREQEEKIQE-QEEKIREQEEKIREQEEMTQEQE-EKMGEQEEKMCEQE 660
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--EAAAQM 121
++ +E +E + EEK++ E+E K +E+EEK + QEE ++QEE+ Q+E+ E +M
Sbjct: 661 EKMQEQEETMWRQEEKIR-EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
Query: 122 KEKEESIQLHQE-AWERHHLRKELRSKNQ 149
+E+EE ++ +E WE+ ++ K Q
Sbjct: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 62.8 bits (151), Expect = 2e-09
Identities = 37/136 (27%), Positives = 79/136 (58%), Gaps = 9/136 (6%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK---DDIKLTAKKEVSKAPEDKKKRLE 61
R++ ++E++ +E+ E+ ++ ++ K + K+ ++E + E+ R E
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 62 DDKRKKEDK----ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE-- 115
+ R++E K E K +++E++ E+E K E+EEK QEE+ ++QEE+ +RQ+E+
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
Query: 116 EAAAQMKEKEESIQLH 131
E +++++EE +Q H
Sbjct: 735 EQEVRLRQQEEKMQEH 750
Score = 62.4 bits (150), Expect = 3e-09
Identities = 50/237 (21%), Positives = 102/237 (43%), Gaps = 23/237 (9%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED-- 62
R+ M E++ + +EK E + ++R + + K+ ++E + E+K + E
Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453
Query: 63 --------------DKRKKEDKERKKKDEEKVKAEEE-----SKKKEEEEKKKHQEEERK 103
++ K++++E + EEK+ +EE K E+EEK + QEE+
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513
Query: 104 KQEEQAKRQQEE--EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFF 161
+QEE+ + Q+E+ E +M +EE I+ +E W E + E+ +
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573
Query: 162 SRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISD 218
+ + ++ ++ + I EQ+ + + I E I E + KI +
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
Score = 61.2 bits (147), Expect = 6e-09
Identities = 46/177 (25%), Positives = 86/177 (48%), Gaps = 18/177 (10%)
Query: 4 ERKKPASMEEK-----DSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK 58
E +K E+K + + +EK + + +E + + + K+ K E ++K
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
Query: 59 RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE--E 116
E +++ +E +E+ ++ EE + E+E K E+EEK QEE+ ++QEE RQ+E+ E
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQ-EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 117 AAAQMKEKEESIQLHQE--------AWERHHLRKELRSKNQNAPDS--RPEENFFSR 163
+++E+EE I+ +E WE+ E K Q + R EE + +
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
Score = 59.7 bits (143), Expect = 2e-08
Identities = 50/177 (28%), Positives = 93/177 (52%), Gaps = 19/177 (10%)
Query: 22 EKDCSERRTVSSKERPKDDIKLTAKK--EVSKAPEDKKKRLEDDKRKKEDKERKK----- 74
EK+ RR ++ I+ +K E K E ++KR E++K ++++K +++
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433
Query: 75 KDEEKVKAEEESKKKEEEEKKKHQEE---ERKKQEEQAKRQQEEEAAAQMKEKEESIQLH 131
+ EEK++ E+E K +E+E+K QEE E++K E+ KRQ++EE M +EE I
Sbjct: 434 RQEEKIR-EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE----MWRQEEKIHEQ 488
Query: 132 QEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQ 185
+E W E+ H ++E + + Q R EE + + ++ ++ + I EQ+
Sbjct: 489 EEIWRQKEKMHEQEE-KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQE 544
Score = 58.9 bits (141), Expect = 3e-08
Identities = 46/188 (24%), Positives = 100/188 (53%), Gaps = 24/188 (12%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
E+++ + +EK + + KE K+ ++E+ E+K +R E+ +KE+K
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEE-----KMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 379
Query: 72 RKKKD---EEKVKAEEESKKKEEEEKKKHQEEERKKQE---EQAKRQQEE----EAAAQM 121
R++++ E++ K E +K E+EK + QEE+R+++E EQ KRQ++E ++
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 439
Query: 122 KEKEESI-QLHQEAW---ERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
+E+EE I + ++ W E+ H ++++R + + R E+ R + + + ++
Sbjct: 440 REQEEKIREQEKKMWRQEEKIHEQEKIREE-----EKRQEQEEMWRQEEKIHEQEEIWRQ 494
Query: 178 LKTITEQQ 185
+ + EQ+
Sbjct: 495 KEKMHEQE 502
Score = 58.9 bits (141), Expect = 3e-08
Identities = 39/154 (25%), Positives = 86/154 (55%), Gaps = 14/154 (9%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERP---KDDIKLTAKKEVSKAPEDKKKRLE 61
R++ M EK+ +E+ E+ ++ + + K+ ++E+ E+K + LE
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397
Query: 62 DDKRKKE---DKERKKKDEEKVKAEEESKKKE-----EEEKKKHQEEERKKQEEQAKRQQ 113
+ ++E ++E K+++EEK++ +E+ +++E +EEK + QEE+ ++QE++ RQ+
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 114 EEEAAAQMKEKEESIQLHQEAW---ERHHLRKEL 144
E+ + +EE Q +E W E+ H ++E+
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Score = 58.5 bits (140), Expect = 4e-08
Identities = 38/156 (24%), Positives = 82/156 (52%), Gaps = 11/156 (7%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ E+++ +EK + + +E + + +++ K E ++ E ++
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
Query: 65 RKKEDKERKKKDEEKVKAEEES------KKKEEEEKKKHQEEERKKQEEQAKRQQEE--E 116
+ E +E+ + EEK++ +EE+ K +E+E+K + QEE+ ++QEE + Q+E+ E
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707
Query: 117 AAAQMKEKEESIQLHQEAWERHHLR---KELRSKNQ 149
+M E+EE +Q +E R + +E+R + Q
Sbjct: 708 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 743
Score = 58.2 bits (139), Expect = 5e-08
Identities = 46/187 (24%), Positives = 103/187 (55%), Gaps = 18/187 (9%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERP-KDDIKLTAKKEVSKAPEDKKKRLEDD 63
R++ E+++ + +EK + + +E +++ K+ ++++ + E+K++ ED
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE--EEKRQEQEDK 571
Query: 64 KRKKEDKERKKKD-----EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
++E+K R++++ EEK++ E+E K++E+EEK QEE+ ++QEE K Q++EE
Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIR-EQEEKRQEQEEKMWKQEEKIREQEE--KIQEQEE-- 626
Query: 119 AQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL 178
+++E+EE I+ +E + +E + Q EE + ++ ++ ++
Sbjct: 627 -KIREQEEKIREQEEMTQ----EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
Query: 179 KTITEQQ 185
K I EQ+
Sbjct: 682 KKIREQE 688
Score = 57.8 bits (138), Expect = 7e-08
Identities = 38/155 (24%), Positives = 85/155 (54%), Gaps = 17/155 (10%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ E ++ + +EK + + +E K+ ++E+ E+K +R E+
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEE-----KMRRQEEMMWEKEEKMRRQEEMM 358
Query: 65 RKKEDKERKKKD-----EEKVKAEEESKKKEEE-----EKKKHQEEERKKQEEQAKRQQE 114
+KE+K R++++ EEK++ +EE ++EE E+K H++E+ ++QEE KRQ+E
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE--KRQEE 416
Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQ 149
E+ Q K +E+ ++ ++ + +++R + +
Sbjct: 417 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
Score = 57.0 bits (136), Expect = 1e-07
Identities = 44/191 (23%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R+K E+++ + +EK + + +E + + ++ K E ++ E++K
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 65 RKKEDK---ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ- 120
+++K E K++++E +E K +E+EEK QEE+ ++QEE+ +++QEE+ Q
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEK-RQEQEEKMWKQE 611
Query: 121 --MKEKEESIQLHQE---AWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFV 175
++E+EE IQ +E E +E ++ Q EE + + ++
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
Query: 176 KKLKTITEQQR 186
++ + I EQ++
Sbjct: 672 RQEEKIREQEK 682
Score = 56.6 bits (135), Expect = 1e-07
Identities = 44/189 (23%), Positives = 98/189 (51%), Gaps = 15/189 (7%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
+ E++ +E E + +E + K+ ++E + E+K R E+ R++E+K
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK 525
Query: 71 ERKKKDEEKVKAEEESKKKEE----EEKKKHQE----EERKKQEEQAKRQQEEEAAAQMK 122
R++ EEK+ +EE +++E EE+K H++ EE K+QE++ K ++EE +++
Sbjct: 526 IREQ--EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE---KIR 580
Query: 123 EKEESIQLHQE-AWERHHLRKELRSKNQNAPDS-RPEENFFSRLDSSLKKNTAFVKKLKT 180
E+EE + +E E+ R+E K + R +E + +++ +++ +
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Query: 181 ITEQQRDSL 189
+T++Q + +
Sbjct: 641 MTQEQEEKM 649
Score = 55.5 bits (132), Expect = 3e-07
Identities = 44/187 (23%), Positives = 93/187 (49%), Gaps = 13/187 (6%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
R++ M EK+ E+ E+ + +E + + + ++E + E K R E+
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 439
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQEEQAKRQQEE--EAAAQ 120
R++E+K R++ E+K+ +EE ++E+ E++K QE+E ++E+ +QEE +
Sbjct: 440 REQEEKIREQ--EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497
Query: 121 MKEKEESIQLHQE-AWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLK 179
M E+EE I+ +E W + +E K R +E R + +++ ++ +
Sbjct: 498 MHEQEEKIRKQEEKVWRQEEKIREQEEK------IREQEEKMWRQEEKIREQEEMWREEE 551
Query: 180 TITEQQR 186
+ EQ++
Sbjct: 552 KMHEQEK 558
Score = 55.1 bits (131), Expect = 4e-07
Identities = 40/140 (28%), Positives = 71/140 (50%), Gaps = 16/140 (11%)
Query: 34 KERPKDDIKLTAKKEVSKA-----PEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKK 88
KE KL A+ E ++ + ++K +++ +E +E+ ++ EEK++ E+E K
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-EQEEKI 330
Query: 89 KEEEEKKKHQEEERKKQEEQAKRQQE---------EEAAAQMKEKEESIQLHQE-AWERH 138
+E+EEK + QEE ++EE+ +RQ+E M EKEE ++ +E WE+
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390
Query: 139 HLRKELRSKNQNAPDSRPEE 158
+EL K R +E
Sbjct: 391 EKIRELEEKMHEQEKIREQE 410
Score = 55.1 bits (131), Expect = 4e-07
Identities = 40/163 (24%), Positives = 85/163 (52%), Gaps = 15/163 (9%)
Query: 38 KDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD-----EEKVKAEEESKKKEEE 92
+ + K+ +E + E+K + E+ R++E+K R++++ EEK++ +EE E+E
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE-MMWEKE 362
Query: 93 EKKKHQEEERKKQEEQAKRQQE---------EEAAAQMKEKEESIQLHQEAWERHHLRKE 143
EK + QEE ++EE+ +RQ+E E +M E+E+ + ++ E +R++
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 144 LRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
+ + Q A R EE + + ++ ++ + I EQ++
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465
Score = 54.7 bits (130), Expect = 6e-07
Identities = 47/218 (21%), Positives = 103/218 (47%), Gaps = 9/218 (4%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERP--KDDIKLTAKKEVSKAPEDKKKRLEDD 63
++ + E++ + KEK + + +E + + K+ ++E + E+K R E+
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539
Query: 64 KRKKEDKERKK-KDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
R++E+ R++ K E+ K EE K++E+E+K QEE K +E++ K ++EE + +
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE--KIREQEEKVWRQEEKIREQE 597
Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDS--RPEENFFSRLDSSLKKNTAFVKKLKT 180
EK + + ++ W++ +E K Q + EE + + + ++ ++ +
Sbjct: 598 EKRQ--EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 181 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISD 218
+ EQ+ + + I E I E + KI +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE 693
Score = 48.1 bits (113), Expect = 5e-05
Identities = 43/193 (22%), Positives = 90/193 (46%), Gaps = 14/193 (7%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK-------- 56
++K A ++EK L +++ + + V +R + KL ++ +A D
Sbjct: 220 KEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 57 KKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEE- 115
+L+ + E R + +E+ +E K +E EEK + QEE+ ++QEE+ + Q+E+
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 116 -EAAAQMKEKEESIQLHQE-AWERHH-LRKELRSKNQNAPDSRPEENFFSRLDSSLKKNT 172
M EKEE ++ +E WE+ +R++ + R +E + +++
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397
Query: 173 AFVKKLKTITEQQ 185
+ + + I EQ+
Sbjct: 398 EKMHEQEKIREQE 410
Score = 38.5 bits (88), Expect = 0.041
Identities = 56/259 (21%), Positives = 108/259 (41%), Gaps = 47/259 (18%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDK--DSKDSMTEGENLEEDEE--EEEGGAETEEQSGNE 1049
EE IR+ ++ RE K+ +K + ++ E E + E E+ EEE E E++ +
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
Query: 1050 SE-VNEPEE----EEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKH 1104
E + E EE +E + +E +E+EE + +E E + E I+
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR------ 629
Query: 1105 VPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAE 1164
E E+ I+ ++M E ++ + K+ + + + ++ R+ + E
Sbjct: 630 ----EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE---- 681
Query: 1165 SADTMPFVMLTRKGNKQQFKIL-NVPMSSQLAANHWNQQQ---------AEQEERMRMKK 1214
+K +Q+ KI M + W Q++ EQEE+MR ++
Sbjct: 682 -----------KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Query: 1215 LTL---DINERQEQEDYQE 1230
+ ++ RQ++E QE
Sbjct: 731 EKMWEQEVRLRQQEEKMQE 749
Score = 32.7 bits (73), Expect = 2.3
Identities = 29/129 (22%), Positives = 65/129 (50%), Gaps = 16/129 (12%)
Query: 21 KEKDCSE----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
KE+D R T++ +E + + KL K ++ ++ + + + + ++K ++ +
Sbjct: 200 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 259
Query: 77 EEKVKAEEESKKKEEEE---KKKHQEEE-----RKKQEEQAKRQQEEEAAAQMKEK---- 124
+++++AE + KE + K + Q EE R Q+++ K ++EE + +EK
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 125 EESIQLHQE 133
EE I+ +E
Sbjct: 320 EEKIREQEE 328
Score = 31.6 bits (70), Expect = 5.1
Identities = 56/307 (18%), Positives = 115/307 (37%), Gaps = 29/307 (9%)
Query: 976 ISDTLELLRPKIKLCNSLEESIRQVQDL----EREFLIKLGLVNDKDSKDSMTEGENLEE 1031
I + E +R + + EE +R+ +++ E + + ++ +K+ K E E+
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 375
Query: 1032 DE----------EEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTD 1081
+E E+EE E EE+ + ++ E EE+ + E E+ +E+
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435
Query: 1082 SNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVA 1141
K E +E+ E + E+ I +K+ E +Q E + +
Sbjct: 436 EEKIREQEEKIRE--------QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE---- 483
Query: 1142 IPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKI--LNVPMSSQLAANHW 1199
+H + ++ + + E K +Q+ KI M Q
Sbjct: 484 -KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIRE 542
Query: 1200 NQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAP 1259
++ +EE+M ++ + +RQEQED + + +E + R Q K
Sbjct: 543 QEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE 602
Query: 1260 NADLIFK 1266
+ ++K
Sbjct: 603 QEEKMWK 609
Score = 31.2 bits (69), Expect = 6.6
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 7/109 (6%)
Query: 64 KRKKEDK--ERKKKDEEKVKAE-EESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
++KK D+ E K+ + + E + +EE K+K+ + + K Q ++++ + + +
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 121 MKEKEESIQL----HQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLD 165
+K K E +L Q E HL KEL+S + E ++RL+
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Score = 31.2 bits (69), Expect = 6.6
Identities = 38/218 (17%), Positives = 86/218 (39%), Gaps = 17/218 (7%)
Query: 1020 KDSMTEGENLEEDEEE-----EEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEE 1074
K+ M E E +EE EE E EE+ + E +EE+ + ++ EEE+
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 1075 NTDYLTDSNKENETDEE--NTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGES 1132
+ + + K E +++ E I+ E E+ + ++ + E ++R +
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIR----------EQEEKVWRQEEKIREQEEKRQEQE 604
Query: 1133 VKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSS 1192
K+ + + I + + + E + + M + G +++
Sbjct: 605 EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Query: 1193 QLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQE 1230
+ W Q++ +E+ ++++ I E++E QE
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 67.0 bits (162), Expect = 1e-10
Identities = 43/168 (25%), Positives = 94/168 (55%), Gaps = 21/168 (12%)
Query: 28 RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--EDDKRKKEDKERKKKDEEKVKAEEE 85
R +++KER + ++ ++ + E+ K++L E KR +E KE++++ EE+ + E+E
Sbjct: 356 RLQLANKER-SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 86 SKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-AAAQMKEKEESIQ------LHQEAWERH 138
+K++E E+++H EE+ +++EE+ + + E+E Q++E++ ++ LH++A
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE 474
Query: 139 HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
+ RK+L + Q RL LK+ ++ L+ ++QR
Sbjct: 475 YKRKQLEEQRQ-----------AERLQRQLKQERDYLVSLQHQRQEQR 511
Score = 47.4 bits (111), Expect = 9e-05
Identities = 40/166 (24%), Positives = 87/166 (52%), Gaps = 24/166 (14%)
Query: 2 PAERKKPASMEEKDSLPNNK----EKDCSERRTVSSKERPKDDI------------KLTA 45
P ER+ ++ KD + K EKD +E S+E +++ + T
Sbjct: 293 PNERQ--VRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTL 350
Query: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKK 104
+++ + K+R E +R++ ++++++ +E K + E +K+ EE+K++ + EE+++
Sbjct: 351 RRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 105 QEEQAKRQQEEEA----AAQMKEKEESIQL-HQEAWERHHLRKELR 145
+E++ ++QQE E QM+ +EE + H++ + R L +E R
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQR 456
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/174 (22%), Positives = 80/174 (45%), Gaps = 35/174 (20%)
Query: 17 LPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK---------RLEDDKRKK 67
L N + + R+ + ++R ++ K E K E++K+ R E + RK+
Sbjct: 359 LANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQ 418
Query: 68 EDKERKKKDEEKVKAEEESKKKEEEEK--KKHQEEE----------------------RK 103
+++E+++ EE+++ EEE ++ E E++ ++ EEE RK
Sbjct: 419 QEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRK 478
Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKEL-RSKNQNAPDSRP 156
+ EEQ + ++ + Q ++ S+Q HQ +R +K L K +P +P
Sbjct: 479 QLEEQRQAERLQRQLKQERDYLVSLQ-HQRQEQRPVEKKPLYHYKEGMSPSEKP 531
Score = 32.3 bits (72), Expect = 3.0
Identities = 55/265 (20%), Positives = 105/265 (39%), Gaps = 40/265 (15%)
Query: 1001 QDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQ---SGNESEVNEPEE 1057
Q ER+ I+L KD D + +++ E E G+E EE+ SG S +
Sbjct: 292 QPNERQVRIQL-----KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPG 346
Query: 1058 EEGSDNDDDEGEEEEEENTDYLTD---SNKENETDEENTEVMIKGGGLKHVPCVEDEDFI 1114
E D + +E ++ L ++ E +E +++ + +E+
Sbjct: 347 ESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL-----AERQKRIEE---- 397
Query: 1115 QALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVML 1174
Q + LE Q+R E K + + H + Q+R+ E E E ++
Sbjct: 398 QKEQRRRLEEQQRREKELRKQQEREQR--RHYEEQMRREEERRRAEHEQE------YIRR 449
Query: 1175 TRKGNKQQFKILNVPM--SSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEML 1232
+ ++Q +IL + L + +Q EQ + R+++ + +++ DY L
Sbjct: 450 QLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR------QLKQERDYLVSL 503
Query: 1233 QSLAQRPAPANTNRERRPRYQHPKG 1257
Q Q P E++P Y + +G
Sbjct: 504 QHQRQEQRPV----EKKPLYHYKEG 524
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 67.0 bits (162), Expect = 1e-10
Identities = 43/168 (25%), Positives = 94/168 (55%), Gaps = 21/168 (12%)
Query: 28 RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--EDDKRKKEDKERKKKDEEKVKAEEE 85
R +++KER + ++ ++ + E+ K++L E KR +E KE++++ EE+ + E+E
Sbjct: 356 RLQLANKER-SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 86 SKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-AAAQMKEKEESIQ------LHQEAWERH 138
+K++E E+++H EE+ +++EE+ + + E+E Q++E++ ++ LH++A
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE 474
Query: 139 HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
+ RK+L + Q RL LK+ ++ L+ ++QR
Sbjct: 475 YKRKQLEEQRQ-----------AERLQRQLKQERDYLVSLQHQRQEQR 511
Score = 47.4 bits (111), Expect = 9e-05
Identities = 40/166 (24%), Positives = 87/166 (52%), Gaps = 24/166 (14%)
Query: 2 PAERKKPASMEEKDSLPNNK----EKDCSERRTVSSKERPKDDI------------KLTA 45
P ER+ ++ KD + K EKD +E S+E +++ + T
Sbjct: 293 PNERQ--VRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTL 350
Query: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKK 104
+++ + K+R E +R++ ++++++ +E K + E +K+ EE+K++ + EE+++
Sbjct: 351 RRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 105 QEEQAKRQQEEEA----AAQMKEKEESIQL-HQEAWERHHLRKELR 145
+E++ ++QQE E QM+ +EE + H++ + R L +E R
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQR 456
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/174 (22%), Positives = 80/174 (45%), Gaps = 35/174 (20%)
Query: 17 LPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK---------RLEDDKRKK 67
L N + + R+ + ++R ++ K E K E++K+ R E + RK+
Sbjct: 359 LANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQ 418
Query: 68 EDKERKKKDEEKVKAEEESKKKEEEEK--KKHQEEE----------------------RK 103
+++E+++ EE+++ EEE ++ E E++ ++ EEE RK
Sbjct: 419 QEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRK 478
Query: 104 KQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKEL-RSKNQNAPDSRP 156
+ EEQ + ++ + Q ++ S+Q HQ +R +K L K +P +P
Sbjct: 479 QLEEQRQAERLQRQLKQERDYLVSLQ-HQRQEQRPVEKKPLYHYKEGMSPSEKP 531
Score = 32.3 bits (72), Expect = 3.0
Identities = 55/265 (20%), Positives = 105/265 (39%), Gaps = 40/265 (15%)
Query: 1001 QDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQ---SGNESEVNEPEE 1057
Q ER+ I+L KD D + +++ E E G+E EE+ SG S +
Sbjct: 292 QPNERQVRIQL-----KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPG 346
Query: 1058 EEGSDNDDDEGEEEEEENTDYLTD---SNKENETDEENTEVMIKGGGLKHVPCVEDEDFI 1114
E D + +E ++ L ++ E +E +++ + +E+
Sbjct: 347 ESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL-----AERQKRIEE---- 397
Query: 1115 QALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVML 1174
Q + LE Q+R E K + + H + Q+R+ E E E ++
Sbjct: 398 QKEQRRRLEEQQRREKELRKQQEREQR--RHYEEQMRREEERRRAEHEQE------YIRR 449
Query: 1175 TRKGNKQQFKILNVPM--SSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEML 1232
+ ++Q +IL + L + +Q EQ + R+++ + +++ DY L
Sbjct: 450 QLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR------QLKQERDYLVSL 503
Query: 1233 QSLAQRPAPANTNRERRPRYQHPKG 1257
Q Q P E++P Y + +G
Sbjct: 504 QHQRQEQRPV----EKKPLYHYKEG 524
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 67.0 bits (162), Expect = 1e-10
Identities = 43/168 (25%), Positives = 94/168 (55%), Gaps = 21/168 (12%)
Query: 28 RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--EDDKRKKEDKERKKKDEEKVKAEEE 85
R +++KER + ++ ++ + E+ K++L E KR +E KE++++ EE+ + E+E
Sbjct: 356 RLQLANKER-SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 86 SKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-AAAQMKEKEESIQ------LHQEAWERH 138
+K++E E+++H EE+ +++EE+ + + E+E Q++E++ ++ LH++A
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE 474
Query: 139 HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
+ RK+L + Q RL LK+ ++ L+ ++QR
Sbjct: 475 YKRKQLEEQRQ-----------AERLQRQLKQERDYLVSLQHQRQEQR 511
Score = 47.4 bits (111), Expect = 9e-05
Identities = 40/166 (24%), Positives = 87/166 (52%), Gaps = 24/166 (14%)
Query: 2 PAERKKPASMEEKDSLPNNK----EKDCSERRTVSSKERPKDDI------------KLTA 45
P ER+ ++ KD + K EKD +E S+E +++ + T
Sbjct: 293 PNERQ--VRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTL 350
Query: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKK 104
+++ + K+R E +R++ ++++++ +E K + E +K+ EE+K++ + EE+++
Sbjct: 351 RRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 105 QEEQAKRQQEEEA----AAQMKEKEESIQL-HQEAWERHHLRKELR 145
+E++ ++QQE E QM+ +EE + H++ + R L +E R
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQR 456
Score = 32.3 bits (72), Expect = 3.0
Identities = 55/265 (20%), Positives = 105/265 (39%), Gaps = 40/265 (15%)
Query: 1001 QDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQ---SGNESEVNEPEE 1057
Q ER+ I+L KD D + +++ E E G+E EE+ SG S +
Sbjct: 292 QPNERQVRIQL-----KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPG 346
Query: 1058 EEGSDNDDDEGEEEEEENTDYLTD---SNKENETDEENTEVMIKGGGLKHVPCVEDEDFI 1114
E D + +E ++ L ++ E +E +++ + +E+
Sbjct: 347 ESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL-----AERQKRIEE---- 397
Query: 1115 QALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVML 1174
Q + LE Q+R E K + + H + Q+R+ E E E ++
Sbjct: 398 QKEQRRRLEEQQRREKELRKQQEREQR--RHYEEQMRREEERRRAEHEQE------YIRR 449
Query: 1175 TRKGNKQQFKILNVPM--SSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEML 1232
+ ++Q +IL + L + +Q EQ + R+++ + +++ DY L
Sbjct: 450 QLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR------QLKQERDYLVSL 503
Query: 1233 QSLAQRPAPANTNRERRPRYQHPKG 1257
Q Q P E++P Y + +G
Sbjct: 504 QHQRQEQRPV----EKKPLYHYKEG 524
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 67.0 bits (162), Expect = 1e-10
Identities = 43/168 (25%), Positives = 94/168 (55%), Gaps = 21/168 (12%)
Query: 28 RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL--EDDKRKKEDKERKKKDEEKVKAEEE 85
R +++KER + ++ ++ + E+ K++L E KR +E KE++++ EE+ + E+E
Sbjct: 356 RLQLANKER-SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 86 SKKKEEEEKKKHQEEERKKQEEQAKRQQEEE-AAAQMKEKEESIQ------LHQEAWERH 138
+K++E E+++H EE+ +++EE+ + + E+E Q++E++ ++ LH++A
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE 474
Query: 139 HLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQR 186
+ RK+L + Q RL LK+ ++ L+ ++QR
Sbjct: 475 YKRKQLEEQRQ-----------AERLQRQLKQERDYLVSLQHQRQEQR 511
Score = 47.4 bits (111), Expect = 9e-05
Identities = 40/166 (24%), Positives = 87/166 (52%), Gaps = 24/166 (14%)
Query: 2 PAERKKPASMEEKDSLPNNK----EKDCSERRTVSSKERPKDDI------------KLTA 45
P ER+ ++ KD + K EKD +E S+E +++ + T
Sbjct: 293 PNERQ--VRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTL 350
Query: 46 KKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKK 104
+++ + K+R E +R++ ++++++ +E K + E +K+ EE+K++ + EE+++
Sbjct: 351 RRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQR 410
Query: 105 QEEQAKRQQEEEA----AAQMKEKEESIQL-HQEAWERHHLRKELR 145
+E++ ++QQE E QM+ +EE + H++ + R L +E R
Sbjct: 411 REKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQR 456
Score = 32.3 bits (72), Expect = 3.0
Identities = 55/265 (20%), Positives = 105/265 (39%), Gaps = 40/265 (15%)
Query: 1001 QDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQ---SGNESEVNEPEE 1057
Q ER+ I+L KD D + +++ E E G+E EE+ SG S +
Sbjct: 292 QPNERQVRIQL-----KDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPG 346
Query: 1058 EEGSDNDDDEGEEEEEENTDYLTD---SNKENETDEENTEVMIKGGGLKHVPCVEDEDFI 1114
E D + +E ++ L ++ E +E +++ + +E+
Sbjct: 347 ESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLL-----AERQKRIEE---- 397
Query: 1115 QALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVML 1174
Q + LE Q+R E K + + H + Q+R+ E E E ++
Sbjct: 398 QKEQRRRLEEQQRREKELRKQQEREQR--RHYEEQMRREEERRRAEHEQE------YIRR 449
Query: 1175 TRKGNKQQFKILNVPM--SSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEML 1232
+ ++Q +IL + L + +Q EQ + R+++ + +++ DY L
Sbjct: 450 QLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQR------QLKQERDYLVSL 503
Query: 1233 QSLAQRPAPANTNRERRPRYQHPKG 1257
Q Q P E++P Y + +G
Sbjct: 504 QHQRQEQRPV----EKKPLYHYKEG 524
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 65.9 bits (159), Expect = 2e-10
Identities = 42/177 (23%), Positives = 96/177 (54%), Gaps = 3/177 (1%)
Query: 9 ASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKE 68
A++E +E+ E+R + E+ K + E +PE+ ++R + +R++E
Sbjct: 457 AAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERERE 516
Query: 69 DKERKKKDEEKVKAEEESKKKEEE-EKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEES 127
+ K++++E+ K E+ +++++E EK+ +E+E++++ E+ ++Q++E+ + KEKE+
Sbjct: 517 KELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKE 576
Query: 128 IQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQ 184
+Q +E + L KE R K + + R E N ++ +N+ ++ T Q
Sbjct: 577 LQKMKEQEKECELEKE-REKLEEKIEPR-EPNLEPMVEKQESENSCNKEEEPVFTRQ 631
Score = 65.1 bits (157), Expect = 4e-10
Identities = 37/175 (21%), Positives = 96/175 (54%), Gaps = 6/175 (3%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E ++ E++ + K K E+ + K+ ++I+ +++ + ++ +K E +
Sbjct: 467 EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQE 526
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER-----KKQEEQAKRQQEEEAA 118
+ K+ +K+R+++ E++ + E+E +K+ E EK++ QE+E+ K++E++ ++ +E+E
Sbjct: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
Query: 119 AQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTA 173
+++++ E ++ E E +L + + ++ EE F+R DS+ + A
Sbjct: 587 CELEKEREKLEEKIEPRE-PNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEA 640
Score = 52.0 bits (123), Expect = 4e-06
Identities = 35/148 (23%), Positives = 79/148 (53%), Gaps = 19/148 (12%)
Query: 46 KKEVSKAPEDKKKRLEDDKRKKEDK------ERKKKDEEKVKAEEESKKKEEEEKKKHQE 99
+ E+S A E +KR E+++R+ E++ E+ K+ +EK+ E+ EE +++ ++
Sbjct: 452 QSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREK 511
Query: 100 EERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEEN 159
E +++E + +++QE E KE+E+ + QE + L KE + + + + E+
Sbjct: 512 EREREKELEKEQEQERE-----KEREKDRERQQE--KEKELEKEQEKQREMEKERKQEK- 563
Query: 160 FFSRLDSSLKKNTAFVKKLKTITEQQRD 187
+ L++ K+L+ + EQ+++
Sbjct: 564 -----EKELERQKEKEKELQKMKEQEKE 586
Score = 45.8 bits (107), Expect = 3e-04
Identities = 28/142 (19%), Positives = 72/142 (50%), Gaps = 30/142 (21%)
Query: 45 AKKEVSKAPE--DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESK--------------- 87
+K++V+ E +++R + + ++ RK+++EE+ + EE+ K
Sbjct: 434 SKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLG 493
Query: 88 -----------KKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
++ E EK++ +E+E +K++EQ + ++ E+ + +EKE+ ++ QE +
Sbjct: 494 ILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQE--K 551
Query: 137 RHHLRKELRSKNQNAPDSRPEE 158
+ + KE + + + + + E+
Sbjct: 552 QREMEKERKQEKEKELERQKEK 573
Score = 40.8 bits (94), Expect = 0.008
Identities = 22/90 (24%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Query: 70 KERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129
K+R+++ E A E ++K+ EEE+++ +E+ + E+ KR E+ + + E I+
Sbjct: 446 KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR 505
Query: 130 LHQEAWERHHLRKELRSKNQNAPDSRPEEN 159
+ ER KEL + + + E++
Sbjct: 506 EREREKERER-EKELEKEQEQEREKEREKD 534
Score = 39.7 bits (91), Expect = 0.019
Identities = 23/89 (25%), Positives = 43/89 (48%)
Query: 1010 KLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGE 1069
KLG++ + S + + E E +E E E+E E E++ E E + ++E + E E
Sbjct: 491 KLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQE 550
Query: 1070 EEEEENTDYLTDSNKENETDEENTEVMIK 1098
++ E + + KE E +E + + K
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQK 579
Score = 35.4 bits (80), Expect = 0.35
Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 11/117 (9%)
Query: 19 NNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKR---LEDDKRKKEDKERKKK 75
+N + E+R+ S PK + KE + PE+K K+ + + K +K K K
Sbjct: 929 SNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSK 988
Query: 76 DEEKVKAEEESKKKEEEEKK--------KHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
E + S ++EE + K K+E + ++++E E A ++ EK
Sbjct: 989 SETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEK 1045
Score = 34.3 bits (77), Expect = 0.78
Identities = 44/209 (21%), Positives = 90/209 (43%), Gaps = 27/209 (12%)
Query: 339 PPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQ 398
PP P + PF + K D E+ R+ + + + E + R ++
Sbjct: 419 PPDRQAVPGRPGPFPS----------KQQVADEDEIWKQRRRQQSEISAAVERARKRREE 468
Query: 399 YEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGI 458
EE M Q+ A ++ L L DE + L + +P+PEE I + E + E +
Sbjct: 469 -EERRMEEQRKAACAEKLKRL-DEKLGIL-EKQPSPEE------IREREREKEREREKEL 519
Query: 459 WEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDL 518
++++ E D + ++ EK + ++ + + ++ ++ ++ KE+ +
Sbjct: 520 EKEQEQEREKEREKDRERQ------QEKEKELEKEQEKQREMEKERKQEKEKELERQKEK 573
Query: 519 ELELENLEINDDTLELEGGDEAEDLTKKL 547
E EL+ ++ + ELE E E L +K+
Sbjct: 574 EKELQKMKEQEKECELE--KEREKLEEKI 600
Score = 31.6 bits (70), Expect = 5.1
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 4/79 (5%)
Query: 1020 KDSMTEGENLEEDEEEEEGGAETEEQ-SGNESEVNEPEEEEGSDNDDDEGEEEEEENT-- 1076
+ S+ L+E ++ + AE +E +G + EV+ E+ SD DD++G +EN
Sbjct: 293 RPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSD-DDEQGSNSPKENNSE 351
Query: 1077 DYLTDSNKENETDEENTEV 1095
D + +++ NE +E EV
Sbjct: 352 DQGSKASENNENKKETDEV 370
Score = 31.2 bits (69), Expect = 6.6
Identities = 26/103 (25%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
Query: 992 SLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESE 1051
S EE + ++ ERE +L +++ ++ E + + E+E+E E E+Q E E
Sbjct: 500 SPEEIREREREKEREREKELEKEQEQE-REKEREKDRERQQEKEKELEKEQEKQREMEKE 558
Query: 1052 VNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
+ +E+E + E E ++ + + + KE E EE E
Sbjct: 559 RKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIE 601
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 65.5 bits (158), Expect = 3e-10
Identities = 41/185 (22%), Positives = 92/185 (49%), Gaps = 8/185 (4%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
ER++ E++ +E+D RT KER +D + + + D+ K
Sbjct: 328 EREREREREKEKERERERERDRDRDRT---KERDRDRDRERDRDRDRERSSDRNKDRSRS 384
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK-RQQEEEAAAQMK 122
+ K D+ER+++ E + + E E +++ E E+++ +E ER++++++ + R+++EE A + +
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERR 444
Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTIT 182
+ E ++ + A++ E+R + + +R E R + ++ K+LK
Sbjct: 445 KLERKLREKEAAYQERLKNWEIRERKK----TREYEKEAEREEERRREMAKEAKRLKEFL 500
Query: 183 EQQRD 187
E D
Sbjct: 501 EDYDD 505
Score = 60.1 bits (144), Expect = 1e-08
Identities = 33/144 (22%), Positives = 73/144 (50%), Gaps = 7/144 (4%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
ER++ E++ + + ER ++R +D K + + D+ + D
Sbjct: 317 ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSD 376
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
+ K + R+K + + + E E +++ E E+++ +E ER+++ E+ +R++E++ +E
Sbjct: 377 RNKDRSRSREKSRDRERERERERERERERERERERERERERERER-EREREKDKKRDREE 435
Query: 124 KEESIQLHQEAWERHHLRKELRSK 147
EE +A+ER L ++LR K
Sbjct: 436 DEE------DAYERRKLERKLREK 453
Score = 58.5 bits (140), Expect = 4e-08
Identities = 42/168 (25%), Positives = 81/168 (48%), Gaps = 23/168 (13%)
Query: 9 ASMEEKDSLPNNKEKDCSE------------------RRTVSSKERPKDDIKLTAKKEVS 50
A +E DS P K+K+ E + +++ E +D L ++ E+S
Sbjct: 224 APSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISR-EIS 282
Query: 51 KAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK 110
K D K+LE++K KKE + ++ + E + + E +++E E+++ +E ER++++E+ +
Sbjct: 283 KF-RDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341
Query: 111 RQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
++ E + + KE ER R RS ++N SR E
Sbjct: 342 ERERERDRDRDRTKERD---RDRDRERDRDRDRERSSDRNKDRSRSRE 386
Score = 55.1 bits (131), Expect = 4e-07
Identities = 32/179 (17%), Positives = 85/179 (47%), Gaps = 3/179 (1%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDK 70
+EE+ + ++ + R +ER ++ + ++E + E +K++ + +R+++
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350
Query: 71 ERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQL 130
+ K+ ++ + E + ++ E ++ + +E+ R++E E + + + E +
Sbjct: 351 RDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERE 410
Query: 131 HQEAWERHHLRKELRSKNQNAPDSRPEENFFSR--LDSSLK-KNTAFVKKLKTITEQQR 186
+ ER R+ R K++ EE+ + R L+ L+ K A+ ++LK ++R
Sbjct: 411 REREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRER 469
Score = 50.1 bits (118), Expect = 1e-05
Identities = 34/142 (23%), Positives = 73/142 (51%), Gaps = 16/142 (11%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSE-----RRTVSSKERPKDDIKLTAKKEVSKAPEDKKK 58
ERKK E++ + ++ ++ + + + +DD K + K D++K
Sbjct: 468 ERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREK 527
Query: 59 RLEDDKR-KKEDKERKKKDEEKVKAE------EESKKKEEEEKKKHQ----EEERKKQEE 107
+E D+R +K +KE ++ +++ AE E ++ E+E +++ Q +E ++EE
Sbjct: 528 EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE 587
Query: 108 QAKRQQEEEAAAQMKEKEESIQ 129
+ K+++EE+ M+E+EE Q
Sbjct: 588 EEKQEKEEKREEPMEEEEEPEQ 609
Score = 45.8 bits (107), Expect = 3e-04
Identities = 37/186 (19%), Positives = 92/186 (49%), Gaps = 14/186 (7%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
+R++ + + S NK++ S ++ +ER ++ ++E + E +++R +
Sbjct: 362 DRERDRDRDRERSSDRNKDRSRSREKS-RDRERERE-----RERERERERERERERERER 415
Query: 64 KRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKE 123
+R++E + ++KD+++ + E+E ++ E++K + + R+K+ +R + E + K
Sbjct: 416 EREREREREREKDKKRDREEDE---EDAYERRKLERKLREKEAAYQERLKNWEIRERKKT 472
Query: 124 KEESIQLHQEAWERHHLRKE---LRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 180
+E + +E R + KE L+ ++ D R + ++ S+L+K +K
Sbjct: 473 REYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR--GSALQKRLRDREKEME 530
Query: 181 ITEQQR 186
E+ R
Sbjct: 531 ADERDR 536
Score = 45.1 bits (105), Expect = 4e-04
Identities = 38/175 (21%), Positives = 86/175 (49%), Gaps = 30/175 (17%)
Query: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKD-DIKLTAKKEVSKAPEDKKKRLEDD 63
RK + EK++ + K+ R ++E K+ + + ++E++K + K+ LED
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503
Query: 64 KRKKED---------KERKKKDEEKVKAEEESKKKEEEEKKKHQEE-------------E 101
++D ++R + E++++A+E +K+E+EE ++ ++ +
Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQ 563
Query: 102 RKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRP 156
R +QE + +RQ Q+K++ ES + +E E+ R+E + + P+ +P
Sbjct: 564 RMEQEAERRRQ------PQIKQEPESEEEEEEKQEKEEKREE-PMEEEEEPEQKP 611
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 65.5 bits (158), Expect = 3e-10
Identities = 43/144 (29%), Positives = 89/144 (61%), Gaps = 15/144 (10%)
Query: 21 KEKDCSERRTVSSKERPKDDIKLTA---KKEVSKAPEDKKKRLEDDKRKKED-KERKKKD 76
KEK S+ V S+E ++++ +K+ S + E++++R E+++R++E+ +E +++
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269
Query: 77 EEKVKAEEESKKKEEEEKKKHQEEERK----------KQEEQAKRQQEEEAAAQMKEKEE 126
+E+ + EE+ +KEEEEKKK ++E++K +++E+ ++E E+ + +E+EE
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329
Query: 127 SIQLHQEA-WERHHLRKELRSKNQ 149
S L +E E+ L+KE + K Q
Sbjct: 2330 SCSLEEEVDREKEILKKEKQFKLQ 2353
Score = 64.7 bits (156), Expect = 5e-10
Identities = 46/188 (24%), Positives = 105/188 (55%), Gaps = 10/188 (5%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
++ +EE++ +P K + +R+ ++PK+ K +++ + ++ E + +E
Sbjct: 2179 EEEGGIEEEEVIPFLKRR-WRKRKEAKRGDKPKE--KFSSQVDEVESEEHFSEEMESLLD 2235
Query: 66 KKEDKERKKKDEEKVKAEEESKKKEE-EEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEK 124
+ E +E +EE+ + EEE +++EE E+++ ++EE + +E+Q ++++EE+ + ++K
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 125 EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFS-RLDSSLKKNTAFVKKLK--TI 181
+E +Q +E +E ++E+ S+ + S EE S L+ + + +KK K +
Sbjct: 2296 KEEVQEKEEVFEE---KEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352
Query: 182 TEQQRDSL 189
EQ+R SL
Sbjct: 2353 QEQRRKSL 2360
Score = 62.0 bits (149), Expect = 3e-09
Identities = 52/209 (24%), Positives = 107/209 (51%), Gaps = 25/209 (11%)
Query: 32 SSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE------RKKKDEEKVKAEEE 85
S +++ KD+ ++T ++EVS+ E+K++++ +++R +++ RK+ EK +A+EE
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592
Query: 86 SKKKEEEEKKKHQE-----EERKKQEEQAKRQQEEEAAAQMK----EKEESI-----QLH 131
K +EEEK +E EERK + K Q++ AQ + +KEE++ +L
Sbjct: 1593 RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLS 1652
Query: 132 QEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSH 191
QEA + RK+L K + +R EE + + +K++ + +++++
Sbjct: 1653 QEAEKLAQKRKKLAKKWEKV--AREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL--- 1707
Query: 192 DFNGLNLSKYIAEAVASIVEAKLKISDVN 220
D+ L++ + E + E K ++N
Sbjct: 1708 DWQEKELAQELEELEWDMEELSWKEEELN 1736
Score = 60.1 bits (144), Expect = 1e-08
Identities = 47/180 (26%), Positives = 94/180 (52%), Gaps = 16/180 (8%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDD 63
E+++ S EE++ +E+ E V +E + + + +K+V K E+KKK+ ++
Sbjct: 2238 EKQESLSSEEEEEREEEEER---EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 64 KRKK-EDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMK 122
K+++ ++KE +++E++ +EEE++ +EE +EEE EE+ R++E +
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLSDEE----EEEESCSLEEEVDREKE------IL 2344
Query: 123 EKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKK--NTAFVKKLKT 180
+KE+ +L ++ + R+ + S + P + L S LKK +TA K KT
Sbjct: 2345 KKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKT 2404
Score = 53.9 bits (128), Expect = 1e-06
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 26/182 (14%)
Query: 27 ERRTVSSKER-PKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKED------KERKKKDEEK 79
E+R + +E+ + KL+ ++E+ + EDKK + E+ K+ E+ KE++ KDEE+
Sbjct: 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQ--EDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543
Query: 80 VKAEEESKKKEEEEKKKHQEEERKKQEE-------------QAKRQQEEEAAAQMKEK-- 124
V EEE ++ EE++++ EE+R QEE + KR QEE AQ +EK
Sbjct: 1544 VTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLA 1603
Query: 125 EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQ 184
+E QL QE ER + ++ + ++ E F + ++ ++ ++ + + ++
Sbjct: 1604 QEERQLAQE--ERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQK 1661
Query: 185 QR 186
++
Sbjct: 1662 RK 1663
Score = 52.0 bits (123), Expect = 4e-06
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 16/189 (8%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
+++ L EK E ++ K ++K ++V + P+ ++ +K ++ E
Sbjct: 1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELE 1719
Query: 72 RKKKDEEKVKAEEESKKKEE----EEKKKHQEEE-------RKKQEEQAKRQQEEEAAAQ 120
+ D E++ +EE +EE EEKKK EEE K EE+ K QEEE Q
Sbjct: 1720 ELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQ 1779
Query: 121 MKEK--EESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL 178
KEK + ++ +E R++L K R E + + ++ L KN + +
Sbjct: 1780 EKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKR--ERWINSME-ELTKNKMILYQK 1836
Query: 179 KTITEQQRD 187
K + +++++
Sbjct: 1837 KNLAQEKKN 1845
Score = 52.0 bits (123), Expect = 4e-06
Identities = 111/570 (19%), Positives = 226/570 (39%), Gaps = 79/570 (13%)
Query: 3 AERKKPASMEEKDSLPNNKEKDC--SERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 60
A+ KK + +EK+ L KE ER T S K+ + KL ++ E+K +
Sbjct: 1840 AQEKKNLA-QEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQE 1898
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
++ KK++K + +++ V+ E+ KK+E+ ++ + +K Q K++ E
Sbjct: 1899 KETVIKKKEK-LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIA 1957
Query: 121 MKEKEESIQLHQEAWERHHL--RKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKL 178
+EK ++++ + A E+ L KE SK + SR + ++++ L F +KL
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRK--MTQVEQEL-----FERKL 2010
Query: 179 KTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAP 238
+ L H+ + +A + I + KL+ + +F Q A
Sbjct: 2011 SL----EEKILLHE------DRILAMEESEIAKGKLEFTRGQ------RIFVQGQRKLAK 2054
Query: 239 SLLQVWKKHFEARKEEKTPN-----ITKLRTDLRFIAELTIV------GIFTDKEGLSLI 287
+ ++ KK KE N + KL D R + + I +F + LS+
Sbjct: 2055 ASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIE 2114
Query: 288 YEQLK----NIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEI 343
+L + E + R + + ++ ++ K E+ L+ SE+
Sbjct: 2115 QSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV 2174
Query: 344 ISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFA 403
I ++++ + +E K R +E + ++ + E+ + H F+
Sbjct: 2175 ILDDEEE--GGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEH-----FS 2227
Query: 404 MSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDED 463
+ LL + L E + +++ EE + E+E+
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEE--------------------VREEEE 2267
Query: 464 ARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELE 523
R E + + ++ EK + KE K++ +E +E E KE ++ L
Sbjct: 2268 ERKEEE-----EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Query: 524 NLEINDDTLELEGGDEAEDLTKKLLDEQEQ 553
+ E +++ LE E D K++L +++Q
Sbjct: 2323 DEEEEEESCSLE---EEVDREKEILKKEKQ 2349
Score = 47.8 bits (112), Expect = 7e-05
Identities = 129/598 (21%), Positives = 231/598 (38%), Gaps = 81/598 (13%)
Query: 1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPK--DDIKLT---AKKEVSKAPED 55
M E ++ A++EEK + + K RT S ++ K D+ K +K E+
Sbjct: 1427 MSEEVEEMATLEEK--VVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEE 1484
Query: 56 KKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQ-- 113
+KRL ++ K K EE++ E++ K EE ++ K +E+Q K ++
Sbjct: 1485 WEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEV 1544
Query: 114 --EEEAAAQMKEKEESI---QLH---QEAWERHHLRKELRSKNQNAPDSR---PEENFFS 162
EEE + + +EKE+ + Q H + W R H RK R++ + A + R EE +
Sbjct: 1545 TLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIH-RKRARAEKKRAQEERKLAQEEEKLA 1603
Query: 163 RLDSSL-----KKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKIS 217
+ + L K A+VK IT+ R+ + A+ ++ + K+S
Sbjct: 1604 QEERQLAQEERKLAQAYVK----ITQDDREMAQAEGK-------FAQKEETLAQRGEKLS 1652
Query: 218 DVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGI 277
++ A L + W+K AR+EEK +++ I + +
Sbjct: 1653 QE----------AEKLAQKRKKLAKKWEK--VAREEEKLAKKGGKLAEVKNILAQKVEEL 1700
Query: 278 FTDKEGLSLIYEQLKNIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLS 337
++ L Q K + E + + + LV K K A E+ L+
Sbjct: 1701 PQREQNLDW---QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 338 FPPSEIISPE-KQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRH 396
+ ++ E K + LL + L +H ++ E + R+ +++ K +L++ R
Sbjct: 1758 WQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKR- 1816
Query: 397 KQYEEFAMSYQKLLANSQSLADL--LDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDL 454
E + S ++L N L L + +L Q+K +
Sbjct: 1817 ---ERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQR----------------K 1857
Query: 455 EGGIWEDEDARNFYENLIDLK---AFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKE 511
E ++ E + + L+ +K IL + EK Q KE+ KE E K
Sbjct: 1858 ENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKET-VIKKKEKLAETEKKL 1916
Query: 512 VSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKLIVD 569
V D L + E L L LE K+L E + EE + +K + +
Sbjct: 1917 VQVEDSLAKKQEKLAQEKMKLALE--KAMVQGKKRLRGELDIAKEEKALNLEMKRLAE 1972
Score = 45.1 bits (105), Expect = 4e-04
Identities = 139/627 (22%), Positives = 247/627 (39%), Gaps = 134/627 (21%)
Query: 12 EEKDSLPNNKEK-DCSERRTVSSKERPKDDIKLTAKKEVS------KAPEDKKKRLEDDK 64
++ + LP ++ D E+ E + D++ + KE K E+KKK E+++
Sbjct: 1695 QKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754
Query: 65 RKKEDKERKKKDEEKVKAEEESKKKEEEEKKKH-----QEEER----------KKQEEQA 109
+E+ ++E K+ EEE +E+E+ +H +EEER KK +
Sbjct: 1755 ALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQ 1814
Query: 110 KRQ-----------------------QEEEAAAQMKEK----EESIQLHQEAWERHHLRK 142
KR+ QE++ AQ KEK +E++ ++E H ++
Sbjct: 1815 KRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERL-THSKKQ 1873
Query: 143 ELRSKNQ----NAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNL 198
++ KN+ N ++ EE ++ +KK + K + Q DSL+ L
Sbjct: 1874 LVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLV-QVEDSLAKKQEKLAQ 1932
Query: 199 SKYIAEAVASIVEAKLKIS---DVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKEEK 255
K ++V+ K ++ D+ +L +R A+ L++ E + +
Sbjct: 1933 EKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVE----GKETLSKGE 1988
Query: 256 TPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADR----ESHTHVSVVISF 311
TP ++ R + EL F K L + K +++ DR E + F
Sbjct: 1989 TPETSRQRKMTQVEQEL-----FERKLSL-----EEKILLHEDRILAMEESEIAKGKLEF 2038
Query: 312 CRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDH 371
R G I RK+ A+ K E +S E + L + +L K L RD
Sbjct: 2039 TR--GQRIFVQGQRKLAKASRKL---IKKRESLSKEPAK-----LNKILKALQK-LTRDE 2087
Query: 372 RELQNTE-------------RQNRRILHSKGELSE-DRHKQYEEFAMSYQKLLANSQSLA 417
R+L E + I SK ++ E D ++ E +KL + LA
Sbjct: 2088 RKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLA 2147
Query: 418 DLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDL----EGGIWEDEDARNFYENLID 473
+ + + ++K T EE K E L EGGI E+E
Sbjct: 2148 NKMRRMIN--KEEKMTEEESK------LARKHSEVILDDEEEGGIEEEE----------- 2188
Query: 474 LKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENL--EI-NDD 530
+P + + + KE+ + D + K S + EV S + E+E+L E+ +
Sbjct: 2189 ---VIPFL----KRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQE 2241
Query: 531 TLELEGGDEAEDLTKKLLDEQEQEDEE 557
+L E +E E+ ++ +E +E+EE
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEE 2268
Score = 44.3 bits (103), Expect = 8e-04
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 20/131 (15%)
Query: 984 RPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETE 1043
+PK K + ++E + + E L + ++S S E E EE+E EEE E E
Sbjct: 2208 KPKEKFSSQVDE-VESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266
Query: 1044 EQ-----SGNESEVNEPEEEEGSDNDDDEGEEEEE--------------ENTDYLTDSNK 1084
E+ G E +V + EEE+ + + EE +E E T+ L+D +
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Query: 1085 ENETDEENTEV 1095
E E+ EV
Sbjct: 2327 EEESCSLEEEV 2337
Score = 40.0 bits (92), Expect = 0.014
Identities = 40/149 (26%), Positives = 71/149 (47%), Gaps = 19/149 (12%)
Query: 955 WKKSLEVWTKDHP---FPIDIDYM-----ISDTLELLRPKIKLCNSL--EESIRQVQDLE 1004
W+K E D P F +D + S+ +E L +++ SL EE + ++ E
Sbjct: 2197 WRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE 2256
Query: 1005 REFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNE----SEVNEPEEEEG 1060
RE + + +++ + EGE + ++EEEE + +E+ E EV E +EE
Sbjct: 2257 RE---EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 1061 SDNDDD--EGEEEEEENTDYLTDSNKENE 1087
S+ + + EEEEEE+ + ++E E
Sbjct: 2314 SEEETESLSDEEEEEESCSLEEEVDREKE 2342
Score = 39.7 bits (91), Expect = 0.019
Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 1014 VNDKDSKDSMTEG-ENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEE 1072
V++ +S++ +E E+L ++ E++E + EE+ E E E EE + + E EE E
Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 1073 EENTDYLTDSNKENETDEENTEVMIK 1098
E+ + + K+ + +++ EV K
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEK 2302
Score = 37.4 bits (85), Expect = 0.092
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 1016 DKDSKDSMTEGENLEEDEE-EEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEE 1074
DK + ++ + +E +E EE + +E ES +E EEE + + +E E EEE
Sbjct: 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266
Query: 1075 NTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLE 1123
+ +E + ++E E K K E E+ + +++M E
Sbjct: 2267 EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315
Score = 37.0 bits (84), Expect = 0.12
Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 7/136 (5%)
Query: 38 KDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKH 97
K+ K KK K+P+ +K ++ + RK +R+ EE+ +EE + EEK
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKE-RKVGKIKREMTKEERDMSEEVEEMATLEEKVVK 1443
Query: 98 QEEERKKQEEQAKRQQEEEAAAQMK----EKEESIQLHQEAWERHHLRKELRSKNQNAPD 153
QE + E Q ++A + K E +S + +E WE+ L++E +Q
Sbjct: 1444 QEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEE-EKLHQAGEK 1502
Query: 154 SRPEENFFSRLDSSLK 169
PEE D LK
Sbjct: 1503 LSPEEEMLQE-DKKLK 1517
Score = 36.2 bits (82), Expect = 0.21
Identities = 38/163 (23%), Positives = 65/163 (39%), Gaps = 52/163 (31%)
Query: 975 MISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEE 1034
+ D +L R + KL N + I + + + E +SK + E + +DEE
Sbjct: 2132 LTKDEKKLARKQRKLANKMRRMINKEEKMTEE-----------ESKLARKHSEVILDDEE 2180
Query: 1035 EEEGGAETEE---------------QSGNE------SEVNEPEEEEG------------- 1060
E GG E EE + G++ S+V+E E EE
Sbjct: 2181 E--GGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELE 2238
Query: 1061 -----SDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIK 1098
S +++E EEEEE + + + +E + +EE E ++
Sbjct: 2239 KQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281
Score = 31.6 bits (70), Expect = 5.1
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 21/138 (15%)
Query: 11 MEEKDSLPNNKEKDCSERRTVSSKERPKDDIK------------LTAKKEVSKAPEDKKK 58
+ K+ +P +E+ + R + E + +K +T KE+SK E K
Sbjct: 1337 IRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTF 1396
Query: 59 RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
+ K K+ ++ +K+ + K + E K EE + EE EE+ +Q E
Sbjct: 1397 Q----KSPKQGRKAVQKERKVGKIKREMTK--EERDMSEEVEEMATLEEKVVKQ---EGK 1447
Query: 119 AQMKEKEESIQLHQEAWE 136
M E+ S Q ++AW+
Sbjct: 1448 LVMIERTPSWQDWKKAWD 1465
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 65.5 bits (158), Expect = 3e-10
Identities = 48/196 (24%), Positives = 97/196 (49%), Gaps = 18/196 (9%)
Query: 2 PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE 61
PA PA + S P++ + +T + P++ +L A+K + +++++ E
Sbjct: 445 PAPVPTPAMV----SAPSSTVNASASVKTSAGTTDPEEATRLLAEKR--RLAREQREKEE 498
Query: 62 DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE------- 114
++R++E+ ER+K++E + EE + EEE ++ + E+ +++EEQ +RQ E
Sbjct: 499 RERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALRER 558
Query: 115 EEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
EEA ++KEE ++ +EA +R+E Q R E RL+ +K+
Sbjct: 559 EEAERAQRQKEEEARVREEA---ERVRQEREKHFQREEQERLERK--KRLEEIMKRTRRT 613
Query: 175 VKKLKTITEQQRDSLS 190
K ++Q+ ++
Sbjct: 614 EATDKKTSDQRNGDIA 629
Score = 44.7 bits (104), Expect = 6e-04
Identities = 24/96 (25%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 19 NNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEE 78
+++++ ERR K+ +I ++E +A + +K LE+ K++ E+ +R+K++
Sbjct: 64 DDRQRLARERREEREKQLAAREIVWLEREE--RARQHYEKHLEERKKRLEE-QRQKEERR 120
Query: 79 KVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
+ EE+ +++ EE+K++H+ R+ E K +Q+
Sbjct: 121 RAAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQK 156
Score = 44.3 bits (103), Expect = 8e-04
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 21/122 (17%)
Query: 35 ERPKDDIKLTAKKEVSKAPE---------------DKKKRLEDDKRKKEDKERKKKDEEK 79
E D K+ KK S P D L D R++ +ER+++ E++
Sbjct: 21 ETAPDSYKVQDKKNASSRPASAISGQNNNHSGNKPDPPPVLRVDDRQRLARERREEREKQ 80
Query: 80 VKAEEESKKKEEEEKKKHQE---EERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWE 136
+ A E + EE ++H E EERKK+ E+ +RQ+EE A ++EK Q +E E
Sbjct: 81 LAAREIVWLEREERARQHYEKHLEERKKRLEE-QRQKEERRRAAVEEKRR--QRLEEDKE 137
Query: 137 RH 138
RH
Sbjct: 138 RH 139
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/96 (23%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 55 DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEE---EEKKKHQEEERKKQEEQAKR 111
D ++RL ++R++ +K+ ++ ++ EE +++ E EE+KK EE+R+K+E +
Sbjct: 64 DDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAA 123
Query: 112 QQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSK 147
+E+ ++KE + + ER K+ ++
Sbjct: 124 VEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNR 159
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 33 SKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEE 92
++ER ++ K A +E+ +++ R +K +E RKK+ EE+ + EE + EE
Sbjct: 70 ARERREEREKQLAAREIVWLEREERARQHYEKHLEE---RKKRLEEQRQKEERRRAAVEE 126
Query: 93 EKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEES 127
++++ EE++++ E +R E + K S
Sbjct: 127 KRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWS 161
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 64.7 bits (156), Expect = 5e-10
Identities = 49/174 (28%), Positives = 80/174 (45%), Gaps = 20/174 (11%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK---KKRL 60
E K A E+ + P +EK S++ KE PK ++ + V K E K KK
Sbjct: 837 EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE 896
Query: 61 EDDKRK--------------KEDKERKKKDEEKVKAEEESKKKEEEE--KKKHQEEERKK 104
+DK+K KED + K+K E K +++K KE + +KK E+K
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKD 956
Query: 105 QEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEE 158
+E+ ++ EE+ + K KE+ L +E + K +S + + DS+P E
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDKTLSKEP-SKPKAEKAEKSSSTDQKDSKPPE 1009
Score = 56.2 bits (134), Expect = 2e-07
Identities = 47/162 (29%), Positives = 75/162 (46%), Gaps = 9/162 (5%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSE-RRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62
E K PA E + EK S + V S E+ K +K AK + P KK+ ++
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP--KKEEVKS 822
Query: 63 DKRKKEDKERKKKDEEKVKAEEESKKK--EEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 120
+++E + K E KAEEE + EEKK ++EE K+E + +E++ A
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAV 882
Query: 121 MKEKEESIQLHQEAWERHHL----RKELRSKNQNAPDSRPEE 158
K KE ++ +E E KE +K + D++P+E
Sbjct: 883 EKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE 924
Score = 53.9 bits (128), Expect = 1e-06
Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 20/138 (14%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKERP-------KDDIKLTAKKEVSKAPEDK 56
E+K+PA + K+S K+++ +++ V + E+ K+D K K EV+K D
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935
Query: 57 KKRLEDDK---------RKKEDKERK-KKDEEKVKAEEESKKKEEEEKKKHQEEERKKQE 106
K E K KK+ KE K KK EEK K E ++K E++K +E + K E
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAK---EDDKTLSKEPSKPKAE 992
Query: 107 EQAKRQQEEEAAAQMKEK 124
+ K ++ ++ EK
Sbjct: 993 KAEKSSSTDQKDSKPPEK 1010
Score = 53.1 bits (126), Expect = 2e-06
Identities = 48/205 (23%), Positives = 90/205 (43%), Gaps = 8/205 (3%)
Query: 2 PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDK----K 57
P + K P E K P + E KE PK + + KE K E K
Sbjct: 782 PEKAKSPVKEEVKS--PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPP 839
Query: 58 KRLEDDKRKKEDKERKKKDEEKVKA-EEESKKKEEEEKKKHQEEERKKQEEQAKRQQ-EE 115
K+ E++K K +KKD +K +A ++E+ K + EEKK+ E+ K+ + +AK+++ E+
Sbjct: 840 KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED 899
Query: 116 EAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFV 175
+ EKE ++ + + + E+ K + ++ + +++ +K
Sbjct: 900 KKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKE 959
Query: 176 KKLKTITEQQRDSLSHDFNGLNLSK 200
+K K E+ + + LSK
Sbjct: 960 EKAKKPEEKPKTEAKAKEDDKTLSK 984
Score = 52.0 bits (123), Expect = 4e-06
Identities = 49/201 (24%), Positives = 87/201 (43%), Gaps = 15/201 (7%)
Query: 2 PAERKKPASMEEKDSLPNNKEKDCSERRT---VSSKERPKDDIKLTAKKEV-SKAPEDKK 57
P + K PA EE S P K + E ++ V S E+ K K AK +K+PE K
Sbjct: 547 PEKAKSPAK-EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605
Query: 58 KRLEDDKRKKEDKERKKKDEEKVKAEEESKKK---------EEEEKKKHQEEERKKQEEQ 108
++++ + + + K+E K AE +S +K + EK K E+E K E+
Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Query: 109 AKRQQEEEAAAQMKEKEE-SIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSS 167
AK + EA + K K + + +++E +S + + E + S
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 168 LKKNTAFVKKLKTITEQQRDS 188
+K+ +K K+ +++ S
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKS 746
Score = 49.7 bits (117), Expect = 2e-05
Identities = 52/186 (27%), Positives = 82/186 (44%), Gaps = 20/186 (10%)
Query: 2 PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK-KEVSKAPEDKKKRL 60
PAE K P EK P +E E+ KE K K + K +K+PE K +
Sbjct: 629 PAEVKSP----EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV 684
Query: 61 EDDKRKKEDKERKKKDEEKVKAEEESKKKEE---EEKKKHQEEERKKQEEQAKRQQEEEA 117
+ + + E + K+E K + +S KEE EK K +E K E+AK +EEA
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 118 AAQMKEK--EESIQLHQEAWE-RHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174
+ K K E++ L ++ E + ++E RS P + F + S +K+
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS---------PADKFPEKAKSPVKEEVKS 795
Query: 175 VKKLKT 180
+K K+
Sbjct: 796 PEKAKS 801
Score = 49.3 bits (116), Expect = 2e-05
Identities = 48/167 (28%), Positives = 79/167 (47%), Gaps = 18/167 (10%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK---KEVSKAPEDKKKRLED 62
K+ A EK P +E E+ K + D AK KE +++P DK
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP---- 782
Query: 63 DKRKKEDKERKKKDEE-KVKAEEESKKKEEEEKKKHQ-----EEERKKQE----EQAKRQ 112
+K K KE K E+ K +E++K E+E KK + +EE K QE E K+
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 113 QEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEEN 159
+EE+A A K +E+ +EA ++ + ++ K + A + +P+E+
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE-KPKES 888
Score = 47.0 bits (110), Expect = 1e-04
Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 2/104 (1%)
Query: 994 EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEE--EEGGAETEEQSGNESE 1051
EE I+ V+ E+E +I + + +TE E E EEE EE G E EE G E E
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500
Query: 1052 VNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEV 1095
P EE + + + +EE + E E + EV
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV 544
Score = 46.6 bits (109), Expect = 2e-04
Identities = 43/145 (29%), Positives = 66/145 (45%), Gaps = 17/145 (11%)
Query: 2 PAERKKPASME----EKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAK-KEVSKAPEDK 56
P + K P E EK P +E E+ KE K K + KE +K PE
Sbjct: 677 PEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA 736
Query: 57 KKRLED-----DKRKKEDKERK---KKDEEKVKAEEESKKKEEE--EKKKHQEEERKKQE 106
K +++ +K K +K + K E K A+EE++ ++ EK K +E K
Sbjct: 737 KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796
Query: 107 EQAKRQQEEEAAAQMKE--KEESIQ 129
E+AK +E+A A KE K+E ++
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVK 821
Score = 45.4 bits (106), Expect = 3e-04
Identities = 47/209 (22%), Positives = 94/209 (44%), Gaps = 11/209 (5%)
Query: 16 SLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKK-RLEDDKRKKEDKERKK 74
SLP K S + K K + ++KE E ++ ++ ++ ++E+KE K+
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480
Query: 75 KD-EEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEE----AAAQMKEKEESIQ 129
++ +E+ EEE + EEE K EE E++AK +EE A A+ EKEE+ +
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA-K 539
Query: 130 LHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSL 189
E + + + ++ P+++ E ++ + +K +K K+ +++ S
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS----PEKAKSPAKEEAKSP 595
Query: 190 SHDFNGLNLSKYIAEAVASIVEAKLKISD 218
+ + + E S EAK + +
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Score = 44.3 bits (103), Expect = 8e-04
Identities = 48/208 (23%), Positives = 80/208 (38%), Gaps = 22/208 (10%)
Query: 2 PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE 61
P + K EE S K + E ++ + + P + K AK+E PE K E
Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP-EKAKSPAKEEAKSPPEAKSPEKE 570
Query: 62 DDKRKKEDKERKK---------------KDEEKVKAEEESKKKEEEEKKKHQEEERK--- 103
+ K E K +K K EK K+ + + K E K +EE K
Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630
Query: 104 --KQEEQAKRQQEEEAAAQMKEKE-ESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENF 160
K E+AK +EEA + K K E + + ++ E +S + + E
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKS 690
Query: 161 FSRLDSSLKKNTAFVKKLKTITEQQRDS 188
+ S +K+ +K K+ +++ S
Sbjct: 691 PEKAKSPVKEEAKSPEKAKSPVKEEAKS 718
Score = 43.5 bits (101), Expect = 0.001
Identities = 120/577 (20%), Positives = 225/577 (38%), Gaps = 65/577 (11%)
Query: 4 ERKKPASMEEKDSLPNNKEKDCSERRTVSSKER--PKDDIKLTAKKEVSKAPEDKKKRLE 61
E K+ EE+ E E ++ ++E P+ + K K+E E K E
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 62 DDKRKKEDKERKKKD---EEKVKAEEESKKKEEEEKKKHQE-EERKKQEEQAKRQQEEEA 117
+ K E K +K +E+ K+ E+K E+EE K E + +K + AK + + A
Sbjct: 537 EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596
Query: 118 AAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKK 177
A+ EK +S + +EA + ++ + ++ + + E + S K+ +K
Sbjct: 597 EAKSPEKAKS-PVKEEAKSPAEAKSPVKEEAKSPAEVKSPE----KAKSPTKEEAKSPEK 651
Query: 178 LKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFA 237
K+ +++ S + + E S V+A+ K + + +
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE------------KAKSPVK 699
Query: 238 PSLLQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINA 297
K ++E K+P K ++ ++ A+ T ++ S + E+ K+ A
Sbjct: 700 EEAKSPEKAKSPVKEEAKSPE--KAKSPVKEEAK-------TPEKAKSPVKEEAKSPEKA 750
Query: 298 DRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKF---NLSFPPSEIISPEKQQPFQN 354
V S + + +S A+KF S E+ SPEK ++
Sbjct: 751 KSPEKAKTLDVKS------PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKA---KS 801
Query: 355 LLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQ 414
LKE + K + + E+++ ++ + K + E K EE A + K ++
Sbjct: 802 PLKEDAKAPEKEIPK-KEEVKSPVKEEEKPQEVK--VKEPPKKAEEEKAPATPK----TE 854
Query: 415 SLADLLDENMPDLPQDKPTPEE-HGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLID 473
D E P KP EE P ++ KP E +E E ED + +
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVE-----KPKESKVEAKKEEAEDKKKVPTPEKE 909
Query: 474 LKAFVPAILFKDNEKSCQNKESNK---DDTKEAKESK-ENKEVSSPDDLELELENLEIND 529
A V K++ K + E K DD K + SK K+ ++P+ + + E + +
Sbjct: 910 APAKVEV---KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966
Query: 530 DTLELEGGDEAEDLT-KKLLDEQEQEDEEASTGSHLK 565
+ + E + +D T K + + E E S+ + K
Sbjct: 967 EKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQK 1003
Score = 41.2 bits (95), Expect = 0.006
Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 3/123 (2%)
Query: 6 KKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKR 65
K+ +EE+ E+ E + +E K++ ++E ++ E++ K ++
Sbjct: 452 KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEG--GEEEEAEGGEEETKSPPAEEA 509
Query: 66 KKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQE-EERKKQEEQAKRQQEEEAAAQMKEK 124
+KE K +E+ K+ E+K E+EE K E + +K + AK + + A+ EK
Sbjct: 510 ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK 569
Query: 125 EES 127
EE+
Sbjct: 570 EEA 572
Score = 40.8 bits (94), Expect = 0.008
Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 13/116 (11%)
Query: 4 ERKKPASMEEK-DSLPNNK------EKDCSERRTVSSKERPKDDI--KLTAKKEVSKAPE 54
E++ PA +E K D+ P K E D ++ + S K+ K K+E +K PE
Sbjct: 907 EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966
Query: 55 DKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAK 110
+K K + + KED + K+ K KA E+++K ++K + E+ +++ AK
Sbjct: 967 EKPKT---EAKAKEDDKTLSKEPSKPKA-EKAEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 37.0 bits (84), Expect = 0.12
Identities = 25/120 (20%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Query: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
EEK + EK+ + + + +++ +KE + +++ E+++ + ++E
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500
Query: 72 RKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE----EEAAAQMKEKEES 127
K E+ + E+ K +E+ K E + ++E+AK E E+A + KE+ +S
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560
Score = 36.6 bits (83), Expect = 0.16
Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 7/95 (7%)
Query: 986 KIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAE---- 1041
KIK+ E+ V++ E + + +++ + EG+ E EEEE G E
Sbjct: 443 KIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETK 502
Query: 1042 ---TEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE 1073
EE + E E P +EE + + E+EE
Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537
Score = 32.3 bits (72), Expect = 3.0
Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 14/106 (13%)
Query: 992 SLEESIRQVQDLEREFLIKLG---LVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGN 1048
SL E + ++ + +K V +K K+++ E EE + EE
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV---------T 471
Query: 1049 ESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTE 1094
E E E +EEEG +++ GEEEE E + T S E E
Sbjct: 472 EEEEKEAKEEEG--KEEEGGEEEEAEGGEEETKSPPAEEAASPEKE 515
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 19/94 (20%)
Query: 2 PAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLE 61
PAE+K+ A ++KD E + +E+PK + +KA ED K +
Sbjct: 944 PAEKKEAAP----------EKKDTKEEKAKKPEEKPKTE---------AKAKEDDKTLSK 984
Query: 62 DDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKK 95
+ + K +K K ++ ++ K E++ K
Sbjct: 985 EPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,948,750
Number of Sequences: 37866
Number of extensions: 2714153
Number of successful extensions: 107358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1398
Number of HSP's successfully gapped in prelim test: 1130
Number of HSP's that attempted gapping in prelim test: 21661
Number of HSP's gapped (non-prelim): 35972
length of query: 1272
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1158
effective length of database: 13,930,794
effective search space: 16131859452
effective search space used: 16131859452
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.