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Search of human proteins with 18087857
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18087857 NEDD8-conjugating enzyme [Homo sapiens]
(185 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18087857 NEDD8-conjugating enzyme [Homo sapiens] 387 e-108
gi|4507791 ubiquitin-conjugating enzyme E2M [Homo sapiens] 117 6e-27
gi|4507773 ubiquitin-conjugating enzyme E2D 1 [Homo sapiens] 86 2e-17
gi|8393719 ubiquitin-conjugating enzyme E2D 4 (putative) [Homo s... 85 3e-17
gi|13489085 ubiquitin-conjugating enzyme E2G 1 [Homo sapiens] 85 3e-17
gi|33149324 ubiquitin-conjugating enzyme E2D 3 isoform 3 [Homo s... 82 2e-16
gi|33149322 ubiquitin-conjugating enzyme E2D 3 isoform 2 [Homo s... 82 3e-16
gi|4507775 ubiquitin-conjugating enzyme E2D 2 isoform 1 [Homo sa... 82 3e-16
gi|33149320 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s... 81 6e-16
gi|33149318 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s... 81 6e-16
gi|33149316 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s... 81 6e-16
gi|33149314 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s... 81 6e-16
gi|33149312 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s... 81 6e-16
gi|33149310 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo s... 81 6e-16
gi|4507777 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo sa... 81 6e-16
gi|4885417 ubiquitin-conjugating enzyme E2K isoform 1 [Homo sapi... 80 1e-15
gi|22749327 ubiquitin-conjugating enzyme E2E 2 [Homo sapiens] 78 4e-15
gi|163660385 ubiquitin-conjugating enzyme E2K isoform 2 [Homo sa... 75 2e-14
gi|33359694 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens] 75 2e-14
gi|5454146 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens] 75 2e-14
gi|33188456 ubiquitin-conjugating enzyme E2D 2 isoform 2 [Homo s... 75 3e-14
gi|4507789 ubiquitin-conjugating enzyme E2L 3 isoform 1 [Homo sa... 73 1e-13
gi|4507779 ubiquitin-conjugating enzyme E2E 1 isoform 1 [Homo sa... 73 2e-13
gi|4507793 ubiquitin-conjugating enzyme E2N [Homo sapiens] 72 4e-13
gi|16357477 ubiquitin-conjugating enzyme Cdc34 [Homo sapiens] 71 6e-13
gi|33359691 ubiquitin-conjugating enzyme E2E 1 isoform 2 [Homo s... 67 9e-12
gi|4759282 ubiquitin-conjugating enzyme E2L 6 isoform 1 [Homo sa... 66 1e-11
gi|22212943 ubiquitin-conjugating enzyme UBC3B [Homo sapiens] 66 2e-11
gi|4507783 ubiquitin-conjugating enzyme E2H isoform 1 [Homo sapi... 63 2e-10
gi|35494003 ubiquitin-conjugating enzyme E2I [Homo sapiens] 62 2e-10
>gi|18087857 NEDD8-conjugating enzyme [Homo sapiens]
Length = 185
Score = 387 bits (993), Expect = e-108
Identities = 185/185 (100%), Positives = 185/185 (100%)
Query: 1 MLTLASKLKRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPN 60
MLTLASKLKRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPN
Sbjct: 1 MLTLASKLKRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPN 60
Query: 61 KLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLL 120
KLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLL
Sbjct: 61 KLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLL 120
Query: 121 REHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYI 180
REHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYI
Sbjct: 121 REHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYI 180
Query: 181 KRYAR 185
KRYAR
Sbjct: 181 KRYAR 185
>gi|4507791 ubiquitin-conjugating enzyme E2M [Homo sapiens]
Length = 183
Score = 117 bits (293), Expect = 6e-27
Identities = 64/162 (39%), Positives = 91/162 (56%), Gaps = 9/162 (5%)
Query: 15 KGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEG 74
K +A S+++ S + K++ EL NLP TC + F DP+ L F+L + PDEG
Sbjct: 12 KEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDPDDLLNFKLVICPDEG 69
Query: 75 YYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTR 134
+Y+ GKF F +V Y PPKVKC T ++HPNI G +CL++LRE W P
Sbjct: 70 FYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE------DWKPVL 123
Query: 135 TLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKV 176
T+ +++GL LF + N +DPLN EAAE ++ F V
Sbjct: 124 TINSIIYGLQYLFLE-PNPEDPLNKEAAEVLQNNRRLFEQNV 164
>gi|4507773 ubiquitin-conjugating enzyme E2D 1 [Homo sapiens]
Length = 147
Score = 85.5 bits (210), Expect = 2e-17
Identities = 49/150 (32%), Positives = 73/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L+ + P C + H + P + YQGG F P Y
Sbjct: 4 KRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPK+ TKI+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKIAFTTKIYHPNINSNGSICLDILRSQ------WSPALTVSKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL + A+ + DKE + ++ ++YA
Sbjct: 117 DPLVPDIAQIYKSDKEKYNRHAREWTQKYA 146
>gi|8393719 ubiquitin-conjugating enzyme E2D 4 (putative) [Homo
sapiens]
Length = 147
Score = 85.1 bits (209), Expect = 3e-17
Identities = 50/150 (33%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+ +L+ + P C + H + P++ YQGG F P Y
Sbjct: 4 KRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV TKI+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTKIYHPNINSNGSICLDILRSQ------WSPALTVSKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D+E + ++ ++YA
Sbjct: 117 DPLVPEIAHTYKADREKYNRLAREWTQKYA 146
>gi|13489085 ubiquitin-conjugating enzyme E2G 1 [Homo sapiens]
Length = 170
Score = 85.1 bits (209), Expect = 3e-17
Identities = 49/156 (31%), Positives = 84/156 (53%), Gaps = 10/156 (6%)
Query: 36 LLVKEVAELEANLPCTCKVHFPDPNKLHCFQ-LTVTPDEGYYQGGKFQFETEVPDAYNMV 94
LL +++AEL N D N L+ ++ L + P + Y+GG F+ P Y +
Sbjct: 9 LLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLR 68
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTG-------WAPTRTLKDVVWGLNSLF 147
PPK+K +T+IWHPN+ + G++C+S+L E D G W P T++ ++ + S+
Sbjct: 69 PPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISML 128
Query: 148 TDLLNFDDPLNIEAAEHHLRDKE-DFRNKVDDYIKR 182
D N D P N++AA+ D+ +F+ KV +++
Sbjct: 129 AD-PNGDSPANVDAAKEWREDRNGEFKRKVARCVRK 163
>gi|33149324 ubiquitin-conjugating enzyme E2D 3 isoform 3 [Homo
sapiens]
Length = 149
Score = 82.4 bits (202), Expect = 2e-16
Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K L KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 6 KCLSKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 65
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 66 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 118
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 119 DPLVPEIARIYKTDRDKYNRISREWTQKYA 148
>gi|33149322 ubiquitin-conjugating enzyme E2D 3 isoform 2 [Homo
sapiens]
Length = 148
Score = 82.0 bits (201), Expect = 3e-16
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDRDKYNRLAREWTEKYA 146
>gi|4507775 ubiquitin-conjugating enzyme E2D 2 isoform 1 [Homo
sapiens]
Length = 147
Score = 81.6 bits (200), Expect = 3e-16
Identities = 49/150 (32%), Positives = 71/150 (47%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+ +L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D+E + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDREKYNRIAREWTQKYA 146
>gi|33149320 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
sapiens]
Length = 147
Score = 80.9 bits (198), Expect = 6e-16
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDRDKYNRISREWTQKYA 146
>gi|33149318 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
sapiens]
Length = 147
Score = 80.9 bits (198), Expect = 6e-16
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDRDKYNRISREWTQKYA 146
>gi|33149316 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
sapiens]
Length = 147
Score = 80.9 bits (198), Expect = 6e-16
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDRDKYNRISREWTQKYA 146
>gi|33149314 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
sapiens]
Length = 147
Score = 80.9 bits (198), Expect = 6e-16
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDRDKYNRISREWTQKYA 146
>gi|33149312 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
sapiens]
Length = 147
Score = 80.9 bits (198), Expect = 6e-16
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDRDKYNRISREWTQKYA 146
>gi|33149310 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
sapiens]
Length = 147
Score = 80.9 bits (198), Expect = 6e-16
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDRDKYNRISREWTQKYA 146
>gi|4507777 ubiquitin-conjugating enzyme E2D 3 isoform 1 [Homo
sapiens]
Length = 147
Score = 80.9 bits (198), Expect = 6e-16
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 7/150 (4%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMV 94
K + KE+++L + P C + H + P++ YQGG F P Y
Sbjct: 4 KRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFK 63
Query: 95 PPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFD 154
PPKV T+I+HPNI G ICL +LR W+P T+ V+ + SL D N D
Sbjct: 64 PPKVAFTTRIYHPNINSNGSICLDILRSQ------WSPALTISKVLLSICSLLCD-PNPD 116
Query: 155 DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DPL E A + D++ + ++ ++YA
Sbjct: 117 DPLVPEIARIYKTDRDKYNRISREWTQKYA 146
>gi|4885417 ubiquitin-conjugating enzyme E2K isoform 1 [Homo
sapiens]
Length = 200
Score = 79.7 bits (195), Expect = 1e-15
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 8/153 (5%)
Query: 33 RDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYN 92
R K KEV + E KV D N P + Y+GG++Q E ++P+ Y
Sbjct: 8 RIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYP 67
Query: 93 MVPPKVKCLTKIWHPNITE-TGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLL 151
PPKV+ +TKIWHPNI+ TG ICL +L++ WA TL+ V+ L +L
Sbjct: 68 FNPPKVRFITKIWHPNISSVTGAICLDILKDQ------WAAAMTLRTVLLSLQALLA-AA 120
Query: 152 NFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
DDP + A + ++ E F+ + YA
Sbjct: 121 EPDDPQDAVVANQYKQNPEMFKQTARLWAHVYA 153
>gi|22749327 ubiquitin-conjugating enzyme E2E 2 [Homo sapiens]
Length = 201
Score = 78.2 bits (191), Expect = 4e-15
Identities = 54/177 (30%), Positives = 86/177 (48%), Gaps = 16/177 (9%)
Query: 9 KRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLT 68
K+ +G S+TAA S S +R+ KE+AE+ + P C P + ++ ++ T
Sbjct: 39 KKKEGKISSKTAAKLSTSAKRIQ-------KELAEITLDPPPNCSAG-PKGDNIYEWRST 90
Query: 69 VT-PDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDG 127
+ P Y+GG F + Y PPKV T+I+H NI G ICL +L+++
Sbjct: 91 ILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDN---- 146
Query: 128 TGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
W+P T+ V+ + SL TD N DPL A ++ ++ + + KRYA
Sbjct: 147 --WSPALTISKVLLSICSLLTD-CNPADPLVGSIATQYMTNRAEHDRMARQWTKRYA 200
>gi|163660385 ubiquitin-conjugating enzyme E2K isoform 2 [Homo
sapiens]
Length = 157
Score = 75.5 bits (184), Expect = 2e-14
Identities = 47/134 (35%), Positives = 66/134 (49%), Gaps = 8/134 (5%)
Query: 33 RDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYN 92
R K KEV + E KV D N P + Y+GG++Q E ++P+ Y
Sbjct: 8 RIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYP 67
Query: 93 MVPPKVKCLTKIWHPNITE-TGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLL 151
PPKV+ +TKIWHPNI+ TG ICL +L++ WA TL+ V+ L +L
Sbjct: 68 FNPPKVRFITKIWHPNISSVTGAICLDILKDQ------WAAAMTLRTVLLSLQALLA-AA 120
Query: 152 NFDDPLNIEAAEHH 165
DDP + A +
Sbjct: 121 EPDDPQDAVVANQN 134
>gi|33359694 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]
Length = 207
Score = 75.5 bits (184), Expect = 2e-14
Identities = 50/177 (28%), Positives = 85/177 (48%), Gaps = 9/177 (5%)
Query: 9 KRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLT 68
++ + + +S +T ++S K + KE+AE+ + P C P + ++ ++ T
Sbjct: 38 RKPSATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAG-PKGDNIYEWRST 96
Query: 69 VT-PDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDG 127
+ P Y+GG F + Y PPKV T+I+H NI G ICL +L+++
Sbjct: 97 ILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDN---- 152
Query: 128 TGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
W+P T+ V+ + SL TD N DPL A +L ++ + + KRYA
Sbjct: 153 --WSPALTISKVLLSICSLLTD-CNPADPLVGSIATQYLTNRAEHDRIARQWTKRYA 206
>gi|5454146 ubiquitin-conjugating enzyme E2E 3 [Homo sapiens]
Length = 207
Score = 75.5 bits (184), Expect = 2e-14
Identities = 50/177 (28%), Positives = 85/177 (48%), Gaps = 9/177 (5%)
Query: 9 KRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLT 68
++ + + +S +T ++S K + KE+AE+ + P C P + ++ ++ T
Sbjct: 38 RKPSATQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAG-PKGDNIYEWRST 96
Query: 69 VT-PDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDG 127
+ P Y+GG F + Y PPKV T+I+H NI G ICL +L+++
Sbjct: 97 ILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDN---- 152
Query: 128 TGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
W+P T+ V+ + SL TD N DPL A +L ++ + + KRYA
Sbjct: 153 --WSPALTISKVLLSICSLLTD-CNPADPLVGSIATQYLTNRAEHDRIARQWTKRYA 206
>gi|33188456 ubiquitin-conjugating enzyme E2D 2 isoform 2 [Homo
sapiens]
Length = 118
Score = 75.1 bits (183), Expect = 3e-14
Identities = 42/114 (36%), Positives = 58/114 (50%), Gaps = 7/114 (6%)
Query: 71 PDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGW 130
P++ YQGG F P Y PPKV T+I+HPNI G ICL +LR W
Sbjct: 11 PNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ------W 64
Query: 131 APTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
+P T+ V+ + SL D N DDPL E A + D+E + ++ ++YA
Sbjct: 65 SPALTISKVLLSICSLLCD-PNPDDPLVPEIARIYKTDREKYNRIAREWTQKYA 117
>gi|4507789 ubiquitin-conjugating enzyme E2L 3 isoform 1 [Homo
sapiens]
Length = 154
Score = 73.2 bits (178), Expect = 1e-13
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 58 DPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICL 117
D L +Q + PD Y G F+ E P Y PPK+ TKI+HPNI E G++CL
Sbjct: 28 DEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCL 87
Query: 118 SLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVD 177
+ I W P V+ L +L D + PL + AE + +D++ F +
Sbjct: 88 PV-----ISAENWKPATKTDQVIQSLIALVND-PQPEHPLRADLAEEYSKDRKKFCKNAE 141
Query: 178 DYIKRY 183
++ K+Y
Sbjct: 142 EFTKKY 147
>gi|4507779 ubiquitin-conjugating enzyme E2E 1 isoform 1 [Homo
sapiens]
Length = 193
Score = 72.8 bits (177), Expect = 2e-13
Identities = 48/171 (28%), Positives = 83/171 (48%), Gaps = 9/171 (5%)
Query: 15 KGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVT-PDE 73
K + + S +++ +S K + KE+A++ + P C P + ++ ++ T+ P
Sbjct: 30 KKKESKVSMSKNSKLLSTSAKRIQKELADITLDPPPNCSAG-PKGDNIYEWRSTILGPPG 88
Query: 74 GYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPT 133
Y+GG F + Y PPKV T+I+H NI G ICL +L+++ W+P
Sbjct: 89 SVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDN------WSPA 142
Query: 134 RTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
T+ V+ + SL TD N DPL A ++ ++ + + KRYA
Sbjct: 143 LTISKVLLSICSLLTD-CNPADPLVGSIATQYMTNRAEHDRMARQWTKRYA 192
>gi|4507793 ubiquitin-conjugating enzyme E2N [Homo sapiens]
Length = 152
Score = 71.6 bits (174), Expect = 4e-13
Identities = 41/128 (32%), Positives = 68/128 (53%), Gaps = 9/128 (7%)
Query: 37 LVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVT-PDEGYYQGGKFQFETEVPDAYNMVP 95
++KE L A K PD + F + + P + ++GG F+ E +P+ Y M
Sbjct: 8 IIKETQRLLAEPVPGIKAE-PDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAA 66
Query: 96 PKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDD 155
PKV+ +TKI+HPN+ + G ICL +L++ W+P ++ V+ + +L + N DD
Sbjct: 67 PKVRFMTKIYHPNVDKLGRICLDILKDK------WSPALQIRTVLLSIQALLS-APNPDD 119
Query: 156 PLNIEAAE 163
PL + AE
Sbjct: 120 PLANDVAE 127
>gi|16357477 ubiquitin-conjugating enzyme Cdc34 [Homo sapiens]
Length = 236
Score = 70.9 bits (172), Expect = 6e-13
Identities = 42/144 (29%), Positives = 74/144 (51%), Gaps = 9/144 (6%)
Query: 35 KLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVT-PDEGYYQGGKFQFETEVPDAYNM 93
K L+ E+ L+ +V D L+ +++ + P YY+GG F+ + P Y
Sbjct: 11 KALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPY 70
Query: 94 VPPKVKCLTKIWHPNITETGEICLSLL-------REHSIDGTGWAPTRTLKDVVWGLNSL 146
PP + LTK+WHPNI ETG++C+S+L + + W PT+ ++ ++ + SL
Sbjct: 71 SPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISL 130
Query: 147 FTDLLNFDDPLNIEAAEHHLRDKE 170
+ F P N++A+ + + KE
Sbjct: 131 LNEPNTF-SPANVDASVMYRKWKE 153
>gi|33359691 ubiquitin-conjugating enzyme E2E 1 isoform 2 [Homo
sapiens]
Length = 176
Score = 67.0 bits (162), Expect = 9e-12
Identities = 47/180 (26%), Positives = 85/180 (47%), Gaps = 13/180 (7%)
Query: 11 DDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEAN-----LPCTCKVHFPDPNKLHCF 65
DD + S +++++S S ++ K+ +++ + L + K P + ++ +
Sbjct: 3 DDDSRASTSSSSSSSSNQQTEKETNTPKKKESKVSMSKNSKLLSTSAKSAGPKGDNIYEW 62
Query: 66 QLTVT-PDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHS 124
+ T+ P Y+GG F + Y PPKV T+I+H NI G ICL +L+++
Sbjct: 63 RSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDN- 121
Query: 125 IDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
W+P T+ V+ + SL TD N DPL A ++ ++ + + KRYA
Sbjct: 122 -----WSPALTISKVLLSICSLLTD-CNPADPLVGSIATQYMTNRAEHDRMARQWTKRYA 175
>gi|4759282 ubiquitin-conjugating enzyme E2L 6 isoform 1 [Homo
sapiens]
Length = 153
Score = 66.2 bits (160), Expect = 1e-11
Identities = 41/147 (27%), Positives = 67/147 (45%), Gaps = 6/147 (4%)
Query: 37 LVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPP 96
+VKE+ +L+ P + D + + + PD+ Y F P Y PP
Sbjct: 7 VVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPEYPFKPP 66
Query: 97 KVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDP 156
+K TKI+HPN+ E G+ICL + I W P V+ LN L + N +P
Sbjct: 67 MIKFTTKIYHPNVDENGQICLPI-----ISSENWKPCTKTCQVLEALNVL-VNRPNIREP 120
Query: 157 LNIEAAEHHLRDKEDFRNKVDDYIKRY 183
L ++ A+ ++ E FR +++ R+
Sbjct: 121 LRMDLADLLTQNPELFRKNAEEFTLRF 147
>gi|22212943 ubiquitin-conjugating enzyme UBC3B [Homo sapiens]
Length = 238
Score = 65.9 bits (159), Expect = 2e-11
Identities = 41/160 (25%), Positives = 79/160 (49%), Gaps = 10/160 (6%)
Query: 28 RRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVT-PDEGYYQGGKFQFETE 86
++++ K L+ E+ L+ ++ D + L+ +++ + P Y+GG F+ +
Sbjct: 4 QQMTSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIK 63
Query: 87 VPDAYNMVPPKVKCLTKIWHPNITETGEICLSLL-------REHSIDGTGWAPTRTLKDV 139
P Y PP + LTK+WHPNI E G++C+S+L + + W PT+ ++ +
Sbjct: 64 FPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTI 123
Query: 140 VWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDY 179
+ + SL + F P N++A+ R D + K +Y
Sbjct: 124 LLSVISLLNEPNTF-SPANVDASV-MFRKWRDSKGKDKEY 161
>gi|4507783 ubiquitin-conjugating enzyme E2H isoform 1 [Homo
sapiens]
Length = 183
Score = 62.8 bits (151), Expect = 2e-10
Identities = 35/113 (30%), Positives = 60/113 (53%), Gaps = 13/113 (11%)
Query: 76 YQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITE-TGEICLSLLREHSIDGTGWAPTR 134
Y+GG ++ ++PD Y P + + KI+HPNI E +G +CL ++ + W
Sbjct: 46 YEGGVWKVRVDLPDKYPFKSPSIGFMNKIFHPNIDEASGTVCLDVINQ------TWTALY 99
Query: 135 TLKDVVWGLNSLFTDLLNFD---DPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
L ++ S LL + DPLN +AA +L E+++ K+ +YI++YA
Sbjct: 100 DLTNI---FESFLPQLLAYPNPIDPLNGDAAAMYLHRPEEYKQKIKEYIQKYA 149
>gi|35494003 ubiquitin-conjugating enzyme E2I [Homo sapiens]
Length = 158
Score = 62.4 bits (150), Expect = 2e-10
Identities = 32/109 (29%), Positives = 55/109 (50%), Gaps = 5/109 (4%)
Query: 76 YQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRT 135
++GG F+ D Y PPK K ++HPN+ +G +CLS+L E W P T
Sbjct: 53 WEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDK----DWRPAIT 108
Query: 136 LKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYA 184
+K ++ G+ L + N DP EA + +++ ++ +V K++A
Sbjct: 109 IKQILLGIQELLNE-PNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFA 156
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,402,775
Number of Sequences: 37866
Number of extensions: 325402
Number of successful extensions: 690
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 598
Number of HSP's gapped (non-prelim): 69
length of query: 185
length of database: 18,247,518
effective HSP length: 96
effective length of query: 89
effective length of database: 14,612,382
effective search space: 1300501998
effective search space used: 1300501998
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.