BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|17978485 vacuolar protein sorting 18 [Homo sapiens] (973 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|17978485 vacuolar protein sorting 18 [Homo sapiens] 1969 0.0 gi|17978477 vacuolar protein sorting 11 [Homo sapiens] 62 2e-09 gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens] 45 3e-04 gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens] 45 3e-04 gi|13569903 ring finger protein 32 [Homo sapiens] 36 0.20 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 35 0.34 gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo ... 33 1.3 gi|166706887 syncoilin, intermediate filament 1 isoform 1 [Homo ... 33 1.3 gi|239756261 PREDICTED: similar to hect domain and RLD 2 [Homo s... 33 1.3 gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l... 33 1.3 gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein... 33 1.7 gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 33 1.7 gi|239755644 PREDICTED: tripartite motif-containing 77 [Homo sap... 32 2.2 gi|239750143 PREDICTED: tripartite motif-containing 77 [Homo sap... 32 2.2 gi|239744448 PREDICTED: hypothetical protein XP_002343148 [Homo ... 32 2.2 gi|225903455 tripartite motif-containing 77 [Homo sapiens] 32 2.2 gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] 32 2.2 gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-l... 32 2.9 gi|81295809 pericentrin [Homo sapiens] 32 2.9 gi|24308069 zinc finger protein 521 [Homo sapiens] 32 3.8 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 32 3.8 gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] 32 3.8 gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 32 3.8 gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] 32 3.8 gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] 32 3.8 gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo sa... 32 3.8 gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo s... 32 3.8 gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s... 32 3.8 gi|7656959 calpain 7 [Homo sapiens] 32 3.8 gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 31 4.9 >gi|17978485 vacuolar protein sorting 18 [Homo sapiens] Length = 973 Score = 1969 bits (5102), Expect = 0.0 Identities = 973/973 (100%), Positives = 973/973 (100%) Query: 1 MASILDEYENSLSRSAVLQPGCPSVGIPHSGYVNAQLEKEVPIFTKQRIDFTPSERITSL 60 MASILDEYENSLSRSAVLQPGCPSVGIPHSGYVNAQLEKEVPIFTKQRIDFTPSERITSL Sbjct: 1 MASILDEYENSLSRSAVLQPGCPSVGIPHSGYVNAQLEKEVPIFTKQRIDFTPSERITSL 60 Query: 61 VVSSNQLCMSLGKDTLLRIDLGKANEPNHVELGRKDDAKVHKMFLDHTGSHLLIALSSTE 120 VVSSNQLCMSLGKDTLLRIDLGKANEPNHVELGRKDDAKVHKMFLDHTGSHLLIALSSTE Sbjct: 61 VVSSNQLCMSLGKDTLLRIDLGKANEPNHVELGRKDDAKVHKMFLDHTGSHLLIALSSTE 120 Query: 121 VLYVNRNGQKVRPLARWKGQLVESVGWNKALGTESSTGPILVGTAQGHIFEAELSASEGG 180 VLYVNRNGQKVRPLARWKGQLVESVGWNKALGTESSTGPILVGTAQGHIFEAELSASEGG Sbjct: 121 VLYVNRNGQKVRPLARWKGQLVESVGWNKALGTESSTGPILVGTAQGHIFEAELSASEGG 180 Query: 181 LFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRSFVIATTRQRLFQFIGRAAEGAE 240 LFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRSFVIATTRQRLFQFIGRAAEGAE Sbjct: 181 LFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRSFVIATTRQRLFQFIGRAAEGAE 240 Query: 241 AQGFSGLFAAYTDHPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGALDCG 300 AQGFSGLFAAYTDHPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGALDCG Sbjct: 241 AQGFSGLFAAYTDHPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGALDCG 300 Query: 301 RPDSLLSEERVWEYPEGVGPGASPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFL 360 RPDSLLSEERVWEYPEGVGPGASPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFL Sbjct: 301 RPDSLLSEERVWEYPEGVGPGASPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFL 360 Query: 361 EKFGPLKHMVKDSSTGQLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPD 420 EKFGPLKHMVKDSSTGQLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPD Sbjct: 361 EKFGPLKHMVKDSSTGQLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPD 420 Query: 421 CLDTVLAREADFCFRQRRYLESARCYALTQSYFEEIALKFLEARQEEALAEFLQRKLASL 480 CLDTVLAREADFCFRQRRYLESARCYALTQSYFEEIALKFLEARQEEALAEFLQRKLASL Sbjct: 421 CLDTVLAREADFCFRQRRYLESARCYALTQSYFEEIALKFLEARQEEALAEFLQRKLASL 480 Query: 481 KPAERTQATLLTTWLTELYLSRLGALQGDPEALTLYRETKECFRTFLSSPRHKEWLFASR 540 KPAERTQATLLTTWLTELYLSRLGALQGDPEALTLYRETKECFRTFLSSPRHKEWLFASR Sbjct: 481 KPAERTQATLLTTWLTELYLSRLGALQGDPEALTLYRETKECFRTFLSSPRHKEWLFASR 540 Query: 541 ASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSP 600 ASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSP Sbjct: 541 ASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSP 600 Query: 601 ILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEVQQVSQAIRYMEFCVNVLGETE 660 ILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEVQQVSQAIRYMEFCVNVLGETE Sbjct: 601 ILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEVQQVSQAIRYMEFCVNVLGETE 660 Query: 661 QAIHNYLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVL 720 QAIHNYLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVL Sbjct: 661 QAIHNYLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVL 720 Query: 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC Sbjct: 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780 Query: 781 PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQEL 840 PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQEL Sbjct: 781 PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQEL 840 Query: 841 RGRYGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQR 900 RGRYGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQR Sbjct: 841 RGRYGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQR 900 Query: 901 KLGAAPPPAKGSARAKEAEGGAATAGPSREQLKADLDELVAAECVYCGELMIRSIDRPFI 960 KLGAAPPPAKGSARAKEAEGGAATAGPSREQLKADLDELVAAECVYCGELMIRSIDRPFI Sbjct: 901 KLGAAPPPAKGSARAKEAEGGAATAGPSREQLKADLDELVAAECVYCGELMIRSIDRPFI 960 Query: 961 DPQRYEEEQLSWL 973 DPQRYEEEQLSWL Sbjct: 961 DPQRYEEEQLSWL 973 >gi|17978477 vacuolar protein sorting 11 [Homo sapiens] Length = 941 Score = 62.4 bits (150), Expect = 2e-09 Identities = 90/428 (21%), Positives = 168/428 (39%), Gaps = 57/428 (13%) Query: 491 LTTWLTELYLSRLGALQGDPEALTLYRETKECFRT--FLSSPRHKEWLFASRASIHELLA 548 LT +L L+ L L Y + K+ + F+ E F +I ++L Sbjct: 436 LTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAI-KVLR 494 Query: 549 SHGDTEHMVYFAVIMQDYERVVAYHCQH-EAYEEALAVLARHRDPQL---FYKFSPILIR 604 G H +Y A +E + + + Y+EAL + + Q ++ IL+ Sbjct: 495 QAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMH 554 Query: 605 HIPRQLVDAWIEM-----------------GSRLDARQLIPALVNYSQGGEVQQVSQAIR 647 HIP Q + G R ++ + IP N + + Sbjct: 555 HIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPR--------ELKA 606 Query: 648 YMEFCVNVLGETEQAIHNYLLSL----YARGRPDSLLAYLEQAGAS---PHRVHYDLKYA 700 ++E V ++ Q I++ LL L +A + + L S R A Sbjct: 607 FLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKA 666 Query: 701 LRLCAEHGHHRACVHVYKVLELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIA 760 L LC H +++Y+ +L+++ + +Q + +Q + E E LW + Sbjct: 667 LVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQ--YRQVISVCERHGEQDPSLWEQAL 724 Query: 761 RHVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQ 820 + ++EED + +A + ++ ++++P T+ H A S ++ Y +Q+LQ Sbjct: 725 SYFARKEEDCKEYVAAVLKH--IENKNLMPPLLVVQTLAHNSTATLSVIRDYL--VQKLQ 780 Query: 821 REMEEATASAQRIRR----------DLQELRGRYGTVEPQDKCATCDFPLLNRPFYLFLC 870 ++ ++ R+RR ++QEL+ + + KC+ C+ L P FLC Sbjct: 781 KQSQQIAQDELRVRRYREETTRIRQEIQELKAS-PKIFQKTKCSICN-SALELPSVHFLC 838 Query: 871 GHMFHADC 878 GH FH C Sbjct: 839 GHSFHQHC 846 >gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens] Length = 829 Score = 45.1 bits (105), Expect = 3e-04 Identities = 46/227 (20%), Positives = 98/227 (43%), Gaps = 21/227 (9%) Query: 661 QAIHNYLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVL 720 Q H +SLYA +LL +L + H L+ AL +C + V++ + Sbjct: 585 QRYHEKQISLYAEYDRPNLLPFLRDS------THCPLEKALEICQQRNFVEETVYLLSRM 638 Query: 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780 A+ + ++ D+ K E+D+ +LW + + + + + + + + Sbjct: 639 GNSRSALKMIMEELHDVDKAIEFAKEQDDG---ELWEDLILYSIDKPPFITGLLNNIGTH 695 Query: 781 --PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQ 838 P+L I + + + I + ++++ L+ YN I + + A + + + + Sbjct: 696 VDPILLIHRI----KEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMH 751 Query: 839 ELRGRYGTVEPQDKCATCDFPLLN----RPF--YLFLCGHMFHADCL 879 + + V+ ++ C +C P+L +PF +F C HMFH +CL Sbjct: 752 RTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 798 >gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens] Length = 854 Score = 45.1 bits (105), Expect = 3e-04 Identities = 46/227 (20%), Positives = 98/227 (43%), Gaps = 21/227 (9%) Query: 661 QAIHNYLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVL 720 Q H +SLYA +LL +L + H L+ AL +C + V++ + Sbjct: 610 QRYHEKQISLYAEYDRPNLLPFLRDS------THCPLEKALEICQQRNFVEETVYLLSRM 663 Query: 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780 A+ + ++ D+ K E+D+ +LW + + + + + + + + Sbjct: 664 GNSRSALKMIMEELHDVDKAIEFAKEQDDG---ELWEDLILYSIDKPPFITGLLNNIGTH 720 Query: 781 --PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQ 838 P+L I + + + I + ++++ L+ YN I + + A + + + + Sbjct: 721 VDPILLIHRI----KEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMH 776 Query: 839 ELRGRYGTVEPQDKCATCDFPLLN----RPF--YLFLCGHMFHADCL 879 + + V+ ++ C +C P+L +PF +F C HMFH +CL Sbjct: 777 RTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823 >gi|13569903 ring finger protein 32 [Homo sapiens] Length = 362 Score = 35.8 bits (81), Expect = 0.20 Identities = 32/114 (28%), Positives = 46/114 (40%), Gaps = 30/114 (26%) Query: 791 FFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQ 850 F F I H +CS YN +I+EL E+++ A + + + L+E G T E Sbjct: 225 FEKKFTEISH--RILCS----YNTNIEELFAEIDQCLAINRSVLQQLEEKCGHEITEEEW 278 Query: 851 DK------------CATCDFPL------------LNRPFYLFLCGHMFHADCLL 880 +K C+ C PL +R L C H+FH CLL Sbjct: 279 EKIQVQALRRETHECSICLAPLSAAGGQRVGAGRRSREMALLSCSHVFHHACLL 332 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 35.0 bits (79), Expect = 0.34 Identities = 34/130 (26%), Positives = 60/130 (46%), Gaps = 8/130 (6%) Query: 728 DLALQVDVDLAKQCA----DLPEEDE--ELRKKLWLKIARHVVQEEEDVQTAMACLASCP 781 D L+++V++ A DL DE E +K+L +K R + E ED + A LA Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRA-LAVAS 1618 Query: 782 LLKIE-DVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQEL 840 K+E D+ + ++ + L+ +++ QRE+EEA AS I +E Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678 Query: 841 RGRYGTVEPQ 850 + ++E + Sbjct: 1679 EKKLKSLEAE 1688 >gi|239787821 syncoilin, intermediate filament 1 isoform 2 [Homo sapiens] Length = 476 Score = 33.1 bits (74), Expect = 1.3 Identities = 51/231 (22%), Positives = 89/231 (38%), Gaps = 28/231 (12%) Query: 637 GEVQQVSQAIRYMEFCVNVLGETEQAIHNYLL------SLYARGRPDSLLAYLEQAGASP 690 G QQ QA+ +E E +Q IH +L + D L AY A A Sbjct: 177 GRFQQCVQAVAQLE------EERDQLIHELVLLREPALQEVQQVHQDILAAYKLHAQAEL 230 Query: 691 HR---------VHYDLKYALRLCAEHGHHRACVH--VYKVLELYEEAVDLALQVDVDLAK 739 R V L + C + + C V + + E A Q+ +LA+ Sbjct: 231 ERDGLREEIRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQ 290 Query: 740 QCADLPEEDEELRKKLWLKIAR---HVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFV 796 ++ E+LR++L ++ H +QE + L + +E+ + P F+ Sbjct: 291 LRDAYQKQKEQLRQQLEAPPSQRDGHFLQESRRLSAQFENLMAESRQDLEE--EYEPQFL 348 Query: 797 TIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTV 847 + KEA +L+ IQE++ + A A+++R + L + V Sbjct: 349 RLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALV 399 >gi|166706887 syncoilin, intermediate filament 1 isoform 1 [Homo sapiens] Length = 482 Score = 33.1 bits (74), Expect = 1.3 Identities = 51/231 (22%), Positives = 89/231 (38%), Gaps = 28/231 (12%) Query: 637 GEVQQVSQAIRYMEFCVNVLGETEQAIHNYLL------SLYARGRPDSLLAYLEQAGASP 690 G QQ QA+ +E E +Q IH +L + D L AY A A Sbjct: 177 GRFQQCVQAVAQLE------EERDQLIHELVLLREPALQEVQQVHQDILAAYKLHAQAEL 230 Query: 691 HR---------VHYDLKYALRLCAEHGHHRACVH--VYKVLELYEEAVDLALQVDVDLAK 739 R V L + C + + C V + + E A Q+ +LA+ Sbjct: 231 ERDGLREEIRLVKQKLFKVTKECVAYQYQLECRQQDVAQFADFREVLTTRATQLSEELAQ 290 Query: 740 QCADLPEEDEELRKKLWLKIAR---HVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFV 796 ++ E+LR++L ++ H +QE + L + +E+ + P F+ Sbjct: 291 LRDAYQKQKEQLRQQLEAPPSQRDGHFLQESRRLSAQFENLMAESRQDLEE--EYEPQFL 348 Query: 797 TIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTV 847 + KEA +L+ IQE++ + A A+++R + L + V Sbjct: 349 RLLERKEAGTKALQRTQAEIQEMKEALRPLQAEARQLRLQNRNLEDQIALV 399 >gi|239756261 PREDICTED: similar to hect domain and RLD 2 [Homo sapiens] Length = 1102 Score = 33.1 bits (74), Expect = 1.3 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 8/57 (14%) Query: 892 QARLEELQRKLGAAPPPAKGSARAKEAEGGAATAGPSRE--------QLKADLDELV 940 + +++ELQ KLG P + + EA G GP E + KADL ELV Sbjct: 509 EQQVKELQEKLGEVKDPVASAQKEPEAARGPGAPGPGGESSSFMDHLEEKADLSELV 565 >gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like protein 1 isoform 2 [Homo sapiens] Length = 602 Score = 33.1 bits (74), Expect = 1.3 Identities = 43/165 (26%), Positives = 63/165 (38%), Gaps = 34/165 (20%) Query: 790 PFFPDFVTIDHFK---EAICSSLKAY---NHHIQELQREMEEATASAQRIRRDLQELRGR 843 P P V + H + E + L+A N I L + EE RIR + LR + Sbjct: 299 PAVPSEVELQHLRKELERVAGELQAQVKNNQRISLLNQRQEE------RIREQEERLRKQ 352 Query: 844 YGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLG 903 ++ Q K L +P +F + + L + +++ELQ KLG Sbjct: 353 EERIQEQHK----SLQQLAKPQSVFEEPNNENKSTL----------QLEQQVKELQEKLG 398 Query: 904 AAPPPAKGSARAKEAEGGAATAGPSRE--------QLKADLDELV 940 + + EA G A GP E + KADL ELV Sbjct: 399 EVKESETSAQKEPEAARGPAAPGPGGESSSFMDHLEEKADLSELV 443 >gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3 isoform 2 [Homo sapiens] Length = 602 Score = 32.7 bits (73), Expect = 1.7 Identities = 42/165 (25%), Positives = 63/165 (38%), Gaps = 34/165 (20%) Query: 790 PFFPDFVTIDHFK---EAICSSLKAY---NHHIQELQREMEEATASAQRIRRDLQELRGR 843 P P V + H + E + L+A N I L + EE RIR + LR + Sbjct: 299 PAVPSEVELQHLRKELERVAGELQAQVKNNQRISLLNQRQEE------RIREQEERLRKQ 352 Query: 844 YGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLG 903 ++ Q K L +P +F + + + L + +++ELQ KLG Sbjct: 353 EERIQEQHK----SLQQLAKPQSVFKEPNNENKNAL----------QLEQQVKELQEKLG 398 Query: 904 AAPPPAKGSARAKEAEGGAATAGPSRE--------QLKADLDELV 940 + + EA G GP E + KADL ELV Sbjct: 399 EVKETETSAQKEPEAARGPGAPGPGGESSSFMDHLEEKADLSELV 443 >gi|148762940 DVL-binding protein DAPLE [Homo sapiens] Length = 2028 Score = 32.7 bits (73), Expect = 1.7 Identities = 17/45 (37%), Positives = 26/45 (57%) Query: 808 SLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDK 852 SL++ +H Q L+ E+ E A Q +RRDL+ LR +E +K Sbjct: 774 SLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEGAEK 818 >gi|239755644 PREDICTED: tripartite motif-containing 77 [Homo sapiens] Length = 455 Score = 32.3 bits (72), Expect = 2.2 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 17/109 (15%) Query: 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780 E+YE+ +++ + DV+L + D+ + +E LR + Q L++ Sbjct: 233 EMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAM--------------PQPVNPQLSAW 278 Query: 781 PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATAS 829 + + + L FF ++T+D ICS+ K ++ LQ +++ S Sbjct: 279 TITGVSERLNFFRVYITLD---RKICSNHKLLFEDLRHLQCSLDDTDMS 324 >gi|239750143 PREDICTED: tripartite motif-containing 77 [Homo sapiens] Length = 455 Score = 32.3 bits (72), Expect = 2.2 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 17/109 (15%) Query: 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780 E+YE+ +++ + DV+L + D+ + +E LR + Q L++ Sbjct: 233 EMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAM--------------PQPVNPQLSAW 278 Query: 781 PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATAS 829 + + + L FF ++T+D ICS+ K ++ LQ +++ S Sbjct: 279 TITGVSERLNFFRVYITLD---RKICSNHKLLFEDLRHLQCSLDDTDMS 324 >gi|239744448 PREDICTED: hypothetical protein XP_002343148 [Homo sapiens] Length = 450 Score = 32.3 bits (72), Expect = 2.2 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 17/109 (15%) Query: 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780 E+YE+ +++ + DV+L + D+ + +E LR + Q L++ Sbjct: 228 EMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAM--------------PQPVNPQLSAW 273 Query: 781 PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATAS 829 + + + L FF ++T+D ICS+ K ++ LQ +++ S Sbjct: 274 TITGVSERLNFFRVYITLD---RKICSNHKLLFEDLRHLQCSLDDTDMS 319 >gi|225903455 tripartite motif-containing 77 [Homo sapiens] Length = 450 Score = 32.3 bits (72), Expect = 2.2 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 17/109 (15%) Query: 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780 E+YE+ +++ + DV+L + D+ + +E LR + Q L++ Sbjct: 228 EMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAM--------------PQPVNPQLSAW 273 Query: 781 PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATAS 829 + + + L FF ++T+D ICS+ K ++ LQ +++ S Sbjct: 274 TITGVSERLNFFRVYITLD---RKICSNHKLLFEDLRHLQCSLDDTDMS 319 >gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] Length = 1066 Score = 32.3 bits (72), Expect = 2.2 Identities = 39/124 (31%), Positives = 54/124 (43%), Gaps = 25/124 (20%) Query: 845 GTVEPQDKCATCDFPL---LNRPFYLFLCGHMFHADCLLQAV--RPGLPAYKQARL--EE 897 G V+P KCA C L L P CGH+F A C+L V PA + RL +E Sbjct: 10 GDVDPDLKCALCHKVLEDPLTTP-----CGHVFCAGCVLPWVVQEGSCPARCRGRLSAKE 64 Query: 898 LQRKLGAAPPPAKGSARAKEAEGGAATAGPSR----EQLKADLD--ELVAAECVY--CGE 949 L L P K + + AT G R +QL L+ + A C + CG+ Sbjct: 65 LNHVL-----PLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLERCDFAPARCRHAGCGQ 119 Query: 950 LMIR 953 +++R Sbjct: 120 VLLR 123 >gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-like protein 1 isoform 2 [Homo sapiens] Length = 601 Score = 32.0 bits (71), Expect = 2.9 Identities = 42/171 (24%), Positives = 65/171 (38%), Gaps = 34/171 (19%) Query: 790 PFFPDFVTIDHFK---EAICSSLKAY---NHHIQELQREMEEATASAQRIRRDLQELRGR 843 P P V + H + E + L+A N I L + EE RI+ + LR + Sbjct: 299 PAVPSEVELQHLRKELERVAGELQAQVKKNQRISLLNQRQEE------RIQEQEERLRKQ 352 Query: 844 YGTVEPQDKCATCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLG 903 ++ Q K L +P +F + + + L + +++ELQ KLG Sbjct: 353 EERIQEQHK----SLQQLAKPQSVFEEPNNENKNAL----------QLEQQVKELQEKLG 398 Query: 904 AAPPPAKGSARAKEAEGGAATAGPSRE--------QLKADLDELVAAECVY 946 + + EA G GP E + KADL ELV E + Sbjct: 399 EVKETETSAQKEPEAARGPGAPGPGGESSSFMDHLKEKADLSELVKKELCF 449 >gi|81295809 pericentrin [Homo sapiens] Length = 3336 Score = 32.0 bits (71), Expect = 2.9 Identities = 51/223 (22%), Positives = 94/223 (42%), Gaps = 28/223 (12%) Query: 638 EVQQVSQAIRYMEFCVNVLGETEQAIHNYLLSLYA-----RGRPDSLLAYLEQAGASPHR 692 E Q+ +A+R + L T +A+H L R +P L A LEQ+ P Sbjct: 2825 EAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELEQS--HPRL 2882 Query: 693 VHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAV-DLALQVDVDLAK------QCADLP 745 + + A R AE A ++ + +E + +L LQ DL K DL Sbjct: 2883 KEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQTVRDLE 2942 Query: 746 EEDEELRKKLWLKIAR--------HVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFV- 796 +DE +L L AR H+ +++ +++ L S L + F V Sbjct: 2943 SKDEVPGSRLHLGSARRAAGSDADHLREQQRELEAMRQRLLSAARL----LTSFTSQAVD 2998 Query: 797 -TIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQ 838 T++ + + ++ + H ++EL+ ++ T+S +++ +LQ Sbjct: 2999 RTVNDWTSSNEKAVMSLLHTLEELKSDLSRPTSSQKKMAAELQ 3041 >gi|24308069 zinc finger protein 521 [Homo sapiens] Length = 1311 Score = 31.6 bits (70), Expect = 3.8 Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 6/52 (11%) Query: 904 AAPPPAKGSARAKEAEGGAATAGPSREQLKADLDELVAAECVYCGELMIRSI 955 AAPP K R + A+ GPS +Q K V C+YC + + S+ Sbjct: 373 AAPPIPKSRGRKRAAQQTPDMTGPSSKQAK------VTYSCIYCNKQLFSSL 418 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 31.6 bits (70), Expect = 3.8 Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 14/115 (12%) Query: 746 EEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLK------IEDVLPFFPDF---- 795 EE EE +KKL A+ + + EE+ +TA + AS K +ED++ Sbjct: 1388 EELEEAKKKL----AQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTAC 1443 Query: 796 VTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQ 850 T+D + L + + E Q E+E A ++ + +L ++R Y V Q Sbjct: 1444 ATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQ 1498 >gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] Length = 412 Score = 31.6 bits (70), Expect = 3.8 Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 18/114 (15%) Query: 731 LQVDVDLAKQCADLPE-----EDEELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLKI 785 ++++ D AK A L + ++E + W ++ + + E E A L S ++ Sbjct: 181 IKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHS----EV 236 Query: 786 EDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQE 839 E L +F+E +K +HHI +L++++ AS ++ R+ L E Sbjct: 237 EKPLM---------NFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 281 >gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] Length = 476 Score = 31.6 bits (70), Expect = 3.8 Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 18/114 (15%) Query: 731 LQVDVDLAKQCADLPE-----EDEELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLKI 785 ++++ D AK A L + ++E + W ++ + + E E A L S ++ Sbjct: 245 IKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHS----EV 300 Query: 786 EDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQE 839 E L +F+E +K +HHI +L++++ AS ++ R+ L E Sbjct: 301 EKPLM---------NFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 345 >gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] Length = 416 Score = 31.6 bits (70), Expect = 3.8 Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 18/114 (15%) Query: 731 LQVDVDLAKQCADLPE-----EDEELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLKI 785 ++++ D AK A L + ++E + W ++ + + E E A L S ++ Sbjct: 185 IKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHS----EV 240 Query: 786 EDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQE 839 E L +F+E +K +HHI +L++++ AS ++ R+ L E Sbjct: 241 EKPLM---------NFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 285 >gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] Length = 336 Score = 31.6 bits (70), Expect = 3.8 Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 18/114 (15%) Query: 731 LQVDVDLAKQCADLPE-----EDEELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLKI 785 ++++ D AK A L + ++E + W ++ + + E E A L S ++ Sbjct: 105 IKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHS----EV 160 Query: 786 EDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQE 839 E L +F+E +K +HHI +L++++ AS ++ R+ L E Sbjct: 161 EKPLM---------NFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 205 >gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo sapiens] Length = 395 Score = 31.6 bits (70), Expect = 3.8 Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 24/151 (15%) Query: 718 KVLELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKI-ARHVVQEEEDVQTAMAC 776 +V + +EE V L+ + D DL D+ E++E + L ++ A+ V+++E DV+ Sbjct: 131 QVAQRHEEKVYLS-RGDEDLG----DMGEDEEAQFRMLMDRLGAQKVLEDESDVKQLWLQ 185 Query: 777 LASCPLLKIEDVLPFFPDFVT--IDHFKEA----------ICSSLKAYNHHIQELQREME 824 L + +L F DF+T I +EA + + AY+ IQ L EME Sbjct: 186 LKK----EEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEME 241 Query: 825 EATAS--AQRIRRDLQELRGRYGTVEPQDKC 853 + S Q + +D + + R +E + C Sbjct: 242 QQIKSEKEQFLLKDTERFQARSQELEQKLLC 272 >gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo sapiens] Length = 462 Score = 31.6 bits (70), Expect = 3.8 Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 24/151 (15%) Query: 718 KVLELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKI-ARHVVQEEEDVQTAMAC 776 +V + +EE V L+ + D DL D+ E++E + L ++ A+ V+++E DV+ Sbjct: 131 QVAQRHEEKVYLS-RGDEDLG----DMGEDEEAQFRMLMDRLGAQKVLEDESDVKQLWLQ 185 Query: 777 LASCPLLKIEDVLPFFPDFVT--IDHFKEA----------ICSSLKAYNHHIQELQREME 824 L + +L F DF+T I +EA + + AY+ IQ L EME Sbjct: 186 LKK----EEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEME 241 Query: 825 EATAS--AQRIRRDLQELRGRYGTVEPQDKC 853 + S Q + +D + + R +E + C Sbjct: 242 QQIKSEKEQFLLKDTERFQARSQELEQKLLC 272 >gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo sapiens] Length = 731 Score = 31.6 bits (70), Expect = 3.8 Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 24/151 (15%) Query: 718 KVLELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKI-ARHVVQEEEDVQTAMAC 776 +V + +EE V L+ + D DL D+ E++E + L ++ A+ V+++E DV+ Sbjct: 131 QVAQRHEEKVYLS-RGDEDLG----DMGEDEEAQFRMLMDRLGAQKVLEDESDVKQLWLQ 185 Query: 777 LASCPLLKIEDVLPFFPDFVT--IDHFKEA----------ICSSLKAYNHHIQELQREME 824 L + +L F DF+T I +EA + + AY+ IQ L EME Sbjct: 186 LKK----EEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEME 241 Query: 825 EATAS--AQRIRRDLQELRGRYGTVEPQDKC 853 + S Q + +D + + R +E + C Sbjct: 242 QQIKSEKEQFLLKDTERFQARSQELEQKLLC 272 >gi|7656959 calpain 7 [Homo sapiens] Length = 813 Score = 31.6 bits (70), Expect = 3.8 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 18/131 (13%) Query: 640 QQVSQAIRYMEFCVNVLGETEQAIHNYLLSLYARGRPDSLLAYLEQAGASPHRVHY--DL 697 ++ +QA+ Y E + L ++ I YL R +L + ++ A P + + DL Sbjct: 34 KEAAQALIYAEMAGSSLENIQEKITEYL------ERVQALHSAVQSKSADPLKSKHQLDL 87 Query: 698 KYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWL 757 + A L + +V +ELY EAVDL L+ + A D+ L+ KL Sbjct: 88 ERAHFLVTQAFDEDEKENVEDAIELYTEAVDLCLKTSYETA---------DKVLQNKL-K 137 Query: 758 KIARHVVQEEE 768 ++AR + E Sbjct: 138 QLARQALDRAE 148 >gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] Length = 3907 Score = 31.2 bits (69), Expect = 4.9 Identities = 28/123 (22%), Positives = 57/123 (46%), Gaps = 6/123 (4%) Query: 718 KVLEL-YEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMAC 776 K LE+ EE V ++++ + + DL ++++ L K+L + R + E+ + Sbjct: 2024 KALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQL--EKMRKFLDEQAIDREHERD 2081 Query: 777 LASCPLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRD 836 + + K+E L P F I + L +H++E + E S ++++RD Sbjct: 2082 VFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLA---NHLKEKTDKCSELLLSKEQLQRD 2138 Query: 837 LQE 839 +QE Sbjct: 2139 IQE 2141 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,555,295 Number of Sequences: 37866 Number of extensions: 1776576 Number of successful extensions: 5936 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 4 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 5887 Number of HSP's gapped (non-prelim): 88 length of query: 973 length of database: 18,247,518 effective HSP length: 112 effective length of query: 861 effective length of database: 14,006,526 effective search space: 12059618886 effective search space used: 12059618886 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.