Guide to the Human Genome
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Search of human proteins with 17975768

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
         (998 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]           2029   0.0  
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...  1412   0.0  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...  1409   0.0  
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]            1408   0.0  
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                 1143   0.0  
gi|4758280 ephrin receptor EphA4 [Homo sapiens]                      1130   0.0  
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi...  1102   0.0  
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...  1097   0.0  
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...  1088   0.0  
gi|4758282 ephrin receptor EphA7 [Homo sapiens]                      1076   0.0  
gi|145312251 EPH receptor A6 isoform a [Homo sapiens]                1035   0.0  
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi...   991   0.0  
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]           885   0.0  
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                      875   0.0  
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]                 803   0.0  
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                     745   0.0  
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi...   535   e-152
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi...   414   e-115
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]                255   2e-67
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]     219   1e-56
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]   218   2e-56
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]   218   2e-56
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]              216   7e-56
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo...   215   1e-55
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]       214   2e-55
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...   214   4e-55
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...   214   4e-55
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...   212   1e-54
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...   212   1e-54
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs...   211   2e-54

>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score = 2029 bits (5256), Expect = 0.0
 Identities = 998/998 (100%), Positives = 998/998 (100%)

Query: 1   MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES 60
           MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES
Sbjct: 1   MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES 60

Query: 61  GWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIP 120
           GWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIP
Sbjct: 61  GWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIP 120

Query: 121 NIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRS 180
           NIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRS
Sbjct: 121 NIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRS 180

Query: 181 FGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGT 240
           FGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGT
Sbjct: 181 FGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGT 240

Query: 241 CIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP 300
           CIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP
Sbjct: 241 CIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP 300

Query: 301 CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWS 360
           CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWS
Sbjct: 301 CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWS 360

Query: 361 EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR 420
           EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR
Sbjct: 361 EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR 420

Query: 421 YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPN 480
           YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPN
Sbjct: 421 YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPN 480

Query: 481 GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF 540
           GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF
Sbjct: 481 GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF 540

Query: 541 ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY 600
           ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY
Sbjct: 541 ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY 600

Query: 601 IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV 660
           IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV
Sbjct: 601 IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV 660

Query: 661 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD 720
           FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD
Sbjct: 661 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD 720

Query: 721 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 780
           SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS
Sbjct: 721 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 780

Query: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW 840
           RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW
Sbjct: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW 840

Query: 841 DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA 900
           DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA
Sbjct: 841 DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA 900

Query: 901 SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM 960
           SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM
Sbjct: 901 SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM 960

Query: 961 TAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV 998
           TAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV
Sbjct: 961 TAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV 998


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
           sapiens]
          Length = 986

 Score = 1412 bits (3656), Expect = 0.0
 Identities = 694/986 (70%), Positives = 809/986 (82%), Gaps = 19/986 (1%)

Query: 23  LLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCN 82
           LLLLPLL       A+EETLMD+   T+EL W  HP SGWEEVSGYDE MN IRTYQVCN
Sbjct: 10  LLLLPLLA------AVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCN 63

Query: 83  VRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVA 142
           V ESSQNNWLRT FI RR   R++VE+KF+VRDC+SIP++PGSCKETFNL+YYEAD D A
Sbjct: 64  VFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSA 123

Query: 143 SASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGA 198
           + + P WMENP+VKVDTIA DESFS++D G    ++NT+VRSFGP+S++GFYLAFQD G 
Sbjct: 124 TKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGG 183

Query: 199 CMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNG 258
           CMSLI+VR FY+KC       A+F ETL+GAE TSLV A G+CI NA EV VP+KLYCNG
Sbjct: 184 CMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNG 243

Query: 259 DGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASIC 318
           DGEW+VP+G C C  G E     + CR CP G++KA QG+  C  CP NSRTTS  A+ C
Sbjct: 244 DGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNC 303

Query: 319 TCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICK 378
            C N +YRAD D  D  CTT+PS P+ VIS+VNETSL+LEW+ PRD GGR+DL+YN+ICK
Sbjct: 304 VCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICK 363

Query: 379 KCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLP 438
            C    G  AC+RC DNV++ PRQLGLTE R++IS LLAHT+YTFE+QAVNGV+ +SP  
Sbjct: 364 SC--GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFS 421

Query: 439 PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK--SEG 496
           P++A+VNITTNQAAPS V  +   S +  S+TLSW+ P++PNGVILDYE++Y+EK  SE 
Sbjct: 422 PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEY 481

Query: 497 IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQ 556
            A+ + S  N+V + GL+  A YV QVRARTVAGYG+YS    F+T +E       +QE+
Sbjct: 482 NATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTE-AEYQTSIQEK 540

Query: 557 LPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY----IAPGMKVYIDPF 612
           LPLI+GS+ AGLVF++AVVVIAIVC R+    +DSEYT+KLQ Y    + PGMK+YIDPF
Sbjct: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPF 600

Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672
           TYEDPNEAVREFAKEID+SCVKIE+VIGAGEFGEVC G LK PG+RE+FVAIKTLK GYT
Sbjct: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660

Query: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732
           E+QRRDFLSEASIMGQFDHPN+I LEGVVTKS PVMI+TEFMEN +LDSFLR NDGQFTV
Sbjct: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720

Query: 733 IQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTY 792
           IQLVGMLRGIAAGMKYL++MNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDD SDPTY
Sbjct: 721 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 780

Query: 793 TSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVE 852
           TS+LGGKIPIRWTAPEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVINA+E
Sbjct: 781 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 840

Query: 853 QDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGM 912
           QDYRLPPPMDCP+ALHQLMLDCW +DRN RPKF QIVNTLDK+IRN  SLK +A   SG+
Sbjct: 841 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 900

Query: 913 SQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTL 972
           + PLLDRT+PDYT+F TV +WL+AIKMG+YKESF +AGF SFD+V+QM  ED+LR+GVTL
Sbjct: 901 NLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTL 960

Query: 973 AGHQKKILSSIQDMRLQMNQTLPVQV 998
           AGHQKKIL+SIQ MR QMNQ   V+V
Sbjct: 961 AGHQKKILNSIQVMRAQMNQIQSVEV 986


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 1409 bits (3648), Expect = 0.0
 Identities = 694/987 (70%), Positives = 810/987 (82%), Gaps = 20/987 (2%)

Query: 23  LLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCN 82
           LLLLPLL       A+EETLMD+   T+EL W  HP SGWEEVSGYDE MN IRTYQVCN
Sbjct: 10  LLLLPLLA------AVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCN 63

Query: 83  VRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVA 142
           V ESSQNNWLRT FI RR   R++VE+KF+VRDC+SIP++PGSCKETFNL+YYEAD D A
Sbjct: 64  VFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSA 123

Query: 143 SASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGA 198
           + + P WMENP+VKVDTIA DESFS++D G    ++NT+VRSFGP+S++GFYLAFQD G 
Sbjct: 124 TKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGG 183

Query: 199 CMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNG 258
           CMSLI+VR FY+KC       A+F ETL+GAE TSLV A G+CI NA EV VP+KLYCNG
Sbjct: 184 CMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNG 243

Query: 259 DGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASIC 318
           DGEW+VP+G C C  G E     + CR CP G++KA QG+  C  CP NSRTTS  A+ C
Sbjct: 244 DGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNC 303

Query: 319 TCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICK 378
            C N +YRAD D  D  CTT+PS P+ VIS+VNETSL+LEW+ PRD GGR+DL+YN+ICK
Sbjct: 304 VCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICK 363

Query: 379 KCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLP 438
            C    G  AC+RC DNV++ PRQLGLTE R++IS LLAHT+YTFE+QAVNGV+ +SP  
Sbjct: 364 SC--GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFS 421

Query: 439 PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK--SEG 496
           P++A+VNITTNQAAPS V  +   S +  S+TLSW+ P++PNGVILDYE++Y+EK  SE 
Sbjct: 422 PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEY 481

Query: 497 IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQ 556
            A+ + S  N+V + GL+  A YV QVRARTVAGYG+YS    F+T +E       +QE+
Sbjct: 482 NATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTE-AEYQTSIQEK 540

Query: 557 LPLIVGSATAGLVFVVAVVVIAIVCLRKQR-HGSDSEYTEKLQQY----IAPGMKVYIDP 611
           LPLI+GS+ AGLVF++AVVVIAIVC R++    +DSEYT+KLQ Y    + PGMK+YIDP
Sbjct: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDP 600

Query: 612 FTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGY 671
           FTYEDPNEAVREFAKEID+SCVKIE+VIGAGEFGEVC G LK PG+RE+FVAIKTLK GY
Sbjct: 601 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGY 660

Query: 672 TERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFT 731
           TE+QRRDFLSEASIMGQFDHPN+I LEGVVTKS PVMI+TEFMEN +LDSFLR NDGQFT
Sbjct: 661 TEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT 720

Query: 732 VIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791
           VIQLVGMLRGIAAGMKYL++MNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDD SDPT
Sbjct: 721 VIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT 780

Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851
           YTS+LGGKIPIRWTAPEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVINA+
Sbjct: 781 YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAI 840

Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSG 911
           EQDYRLPPPMDCP+ALHQLMLDCW +DRN RPKF QIVNTLDK+IRN  SLK +A   SG
Sbjct: 841 EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSG 900

Query: 912 MSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVT 971
           ++ PLLDRT+PDYT+F TV +WL+AIKMG+YKESF +AGF SFD+V+QM  ED+LR+GVT
Sbjct: 901 INLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVT 960

Query: 972 LAGHQKKILSSIQDMRLQMNQTLPVQV 998
           LAGHQKKIL+SIQ MR QMNQ   V+V
Sbjct: 961 LAGHQKKILNSIQVMRAQMNQIQSVEV 987


>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
          Length = 984

 Score = 1408 bits (3645), Expect = 0.0
 Identities = 690/978 (70%), Positives = 811/978 (82%), Gaps = 14/978 (1%)

Query: 26  LPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRE 85
           L LLLL +   A+EETLMDT+  T+EL WT++P SGWEEVSGYDE +N IRTYQVCNV E
Sbjct: 6   LLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFE 65

Query: 86  SSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASAS 145
            +QNNWL T FI RR   R+Y E++FTVRDC+S+PN+PGSCKETFNL+YYE DS +A+  
Sbjct: 66  PNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKK 125

Query: 146 SPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMS 201
           S FW E PY+KVDTIA DESFS++D G    +VNT+VRSFGPL++ GFYLAFQD GACMS
Sbjct: 126 SAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMS 185

Query: 202 LISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGE 261
           L+SVR F+KKC S    FA+FPET+TGAE TSLVIA GTCIPNA EV VP+KLYCNGDGE
Sbjct: 186 LLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGE 245

Query: 262 WMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCH 321
           WMVP+G CTC  G+EP    + C+ CP G++KA Q    C  CP NSR+ + A+ ICTC 
Sbjct: 246 WMVPIGRCTCKPGYEPENSVA-CKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCR 304

Query: 322 NNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCH 381
             +YRAD D  + ACT+VPS PR VIS VNETS+ILEW  PR+ GGRDD+ YN+ICKKC 
Sbjct: 305 TGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCR 364

Query: 382 GAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRY 441
                 +CSRCDDNVEFVPRQLGLTE RV IS L AHT YTF++QA+NGVS KSP PP++
Sbjct: 365 A--DRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQH 422

Query: 442 AAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK--SEGIAS 499
            +VNITTNQAAPS VP +   S++  S+TLSW  PE+PNG+ILDYE++Y+EK  +E  +S
Sbjct: 423 VSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSS 482

Query: 500 TVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPL 559
              SQ N+ ++DGLRP   YVVQVRARTVAGYG++S    F+T ++      +L+EQLPL
Sbjct: 483 MARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTD-DDYKSELREQLPL 541

Query: 560 IVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYI----APGMKVYIDPFTYE 615
           I GSA AG+VFVV++V I+IVC RK+ +  ++ Y++KLQ Y     +PGMK+YIDPFTYE
Sbjct: 542 IAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYE 601

Query: 616 DPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQ 675
           DPNEAVREFAKEIDVS VKIEEVIGAGEFGEV +GRLK PG+RE++VAIKTLK GY+E+Q
Sbjct: 602 DPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQ 661

Query: 676 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQL 735
           RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMI+TEFMEN ALDSFLR NDGQFTVIQL
Sbjct: 662 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQL 721

Query: 736 VGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSS 795
           VGMLRGIAAGMKYL+EMNYVHRDLAARNILVNSNLVCKVSDFGLSR+L+DD SDPTYTSS
Sbjct: 722 VGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781

Query: 796 LGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDY 855
           LGGKIP+RWTAPEAIAYRKFTSASDVWSYGIVMWEVMS+GERPYWDMSNQDVINA+EQDY
Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDY 841

Query: 856 RLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQP 915
           RLPPPMDCP ALHQLMLDCW +DRN RP+F++IVNTLDK+IRN ASLK +A+  +  SQP
Sbjct: 842 RLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQP 901

Query: 916 LLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGH 975
           LLDR++PD+T FTTV DWL AIKM +Y++SF++AGF S  LV QMT+EDLLRIG+TLAGH
Sbjct: 902 LLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGH 961

Query: 976 QKKILSSIQDMRLQMNQT 993
           QKKIL+SI  MR+Q++Q+
Sbjct: 962 QKKILNSIHSMRVQISQS 979


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score = 1143 bits (2956), Expect = 0.0
 Identities = 582/973 (59%), Positives = 718/973 (73%), Gaps = 24/973 (2%)

Query: 37  ALEETLMDTKWVTSELAWTSHPE--SGWEEVSGYDEAMNPIRTYQVCNV-RESSQNNWLR 93
           ALEETL++TK  T++L W + P+    WEE+SG DE  + +RTY+VC+V R   Q +WLR
Sbjct: 15  ALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLR 74

Query: 94  TGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENP 153
           TG++ RR    VY  L+FT+ +C S+P    SCKETF +FYYE+D+D A+A +P WMENP
Sbjct: 75  TGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENP 134

Query: 154 YVKVDTIAPDESFSRLDA----GRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFY 209
           Y+KVDT+A +    +       G+VN K    GPLSKAGFYLAFQDQGACM+L+S+  FY
Sbjct: 135 YIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFY 194

Query: 210 KKCASTTAGFALFPETLTGAEPTSLVI-APGTCIPNAVEVSVPL-KLYCNGDGEWMV-PV 266
           KKCA  T     FPET+    P  LV+   G+C+ +AV    P   LYC  DG+W   PV
Sbjct: 195 KKCAQLTVNLTRFPETV----PRELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPV 250

Query: 267 GACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYR 326
             C+CA G E A   ++CR C  G++K   GEG C PCP NS + +  +++C C   ++R
Sbjct: 251 TGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFR 310

Query: 327 ADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGA 386
           A +D   + CTT PS PR V+S +N +SL LEWS P + GGR+DL Y + C++C   G  
Sbjct: 311 ARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGG-- 368

Query: 387 SACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNI 446
            +C+ C  ++ F P    L E  V +  L     YTFEV A+NGVS  +  P  +  VN+
Sbjct: 369 -SCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNV 427

Query: 447 TTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK-SEGIAST--VTS 503
           TT++  P  V  +R+  SS SSL+L+WA P  P+G +LDYE+KY EK +EG +S   + +
Sbjct: 428 TTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKT 487

Query: 504 QMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGS 563
             N  +L GL+  A Y+VQVRAR+ AGYG + +    +T  +   G    +EQL LI G+
Sbjct: 488 SENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEG---WREQLALIAGT 544

Query: 564 ATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY-IAPGMKVYIDPFTYEDPNEAVR 622
           A  G+V V+ V+V+A++CLRKQ +G ++EY++K  QY I  G KVYIDPFTYEDPNEAVR
Sbjct: 545 AVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVR 604

Query: 623 EFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSE 682
           EFAKEIDVS VKIEEVIGAGEFGEVCRGRLK PG++E  VAIKTLK GYTERQRR+FLSE
Sbjct: 605 EFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSE 664

Query: 683 ASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGI 742
           ASIMGQF+HPNIIRLEGVVT S PVMILTEFMEN ALDSFLRLNDGQFTVIQLVGMLRGI
Sbjct: 665 ASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGI 724

Query: 743 AAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPI 802
           A+GM+YL+EM+YVHRDLAARNILVNSNLVCKVSDFGLSRFLE++ SDPTYTSSLGGKIPI
Sbjct: 725 ASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPI 784

Query: 803 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMD 862
           RWTAPEAIA+RKFTSASD WSYGIVMWEVMS+GERPYWDMSNQDVINA+EQDYRLPPP D
Sbjct: 785 RWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPD 844

Query: 863 CPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVP 922
           CPT+LHQLMLDCW +DRN RP+F Q+V+ LDK+IRN ASLK++A    G S PLLD+  P
Sbjct: 845 CPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQP 904

Query: 923 DYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSS 982
            Y+ F +VG+WL AIKMGRY+ESF +AGF SF+LV+Q++AEDLLRIGVTLAGHQKKIL+S
Sbjct: 905 HYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILAS 964

Query: 983 IQDMRLQMNQTLP 995
           +Q M+ Q     P
Sbjct: 965 VQHMKSQAKPGTP 977


>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
          Length = 986

 Score = 1130 bits (2922), Expect = 0.0
 Identities = 564/963 (58%), Positives = 699/963 (72%), Gaps = 19/963 (1%)

Query: 37  ALEETLMDTKWVTSELAWTSHP-ESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTG 95
           A E TL+D++ V  EL W + P E GWEEVS  DE   PIRTYQVCNV E SQNNWLRT 
Sbjct: 28  ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87

Query: 96  FIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYV 155
           +I R   QRVY+E+KFT+RDCNS+P + G+CKETFNL+YYE+D+D       F  EN +V
Sbjct: 88  WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDND----KERFIRENQFV 143

Query: 156 KVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKK 211
           K+DTIA DESF+++D G    ++NT++R  GPLSK GFYLAFQD GAC++L+SVR FYKK
Sbjct: 144 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 203

Query: 212 CASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTC 271
           C  T    A FP+T+TGA+ +SLV   G+C+ N+ E  VP K+YC  DGEW+VP+G C C
Sbjct: 204 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVP-KMYCGADGEWLVPIGNCLC 262

Query: 272 ATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDS 331
             GHE   +  +C+ C  G YKA   +  C  CPP+S +    A+ CTC   F+RAD+D+
Sbjct: 263 NAGHEE--RSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDA 320

Query: 332 ADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSR 391
           A   CT  PS P  +ISNVNETS+ LEWS P++ GGR D+ YNV+CKKC GAG  S C  
Sbjct: 321 ASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKC-GAGDPSKCRP 379

Query: 392 CDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQA 451
           C   V + P+Q GL   +V I+ LLAHT YTFE+ AVNGVS  +P P +  +V +TTNQA
Sbjct: 380 CGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQA 439

Query: 452 APSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQ 509
           APS +  ++    +  S+ L+W  P+RPNGVIL+YE+KY+EK +   S   V +   +  
Sbjct: 440 APSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTD 499

Query: 510 LDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLV 569
           + GL P   YV  VRART AGYG +S P E  T +              L+V  + +G V
Sbjct: 500 IKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLV--SVSGSV 557

Query: 570 FVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEID 629
            +V +++ A V  R++   S ++     ++++  G++ Y+DPFTYEDPN+AVREFAKEID
Sbjct: 558 VLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEID 617

Query: 630 VSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQF 689
            SC+KIE+VIG GEFGEVC GRLK PG+RE+ VAIKTLK GYT++QRRDFLSEASIMGQF
Sbjct: 618 ASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQF 677

Query: 690 DHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYL 749
           DHPNII LEGVVTK +PVMI+TE+MEN +LD+FLR NDG+FTVIQLVGMLRGI +GMKYL
Sbjct: 678 DHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYL 737

Query: 750 SEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEA 809
           S+M+YVHRDLAARNILVNSNLVCKVSDFG+SR LEDDP +  YT+  GGKIPIRWTAPEA
Sbjct: 738 SDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDP-EAAYTTR-GGKIPIRWTAPEA 795

Query: 810 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQ 869
           IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI A+E+ YRLPPPMDCP ALHQ
Sbjct: 796 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQ 855

Query: 870 LMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTT 929
           LMLDCW ++R+ RPKF QIVN LDKLIRN  SLK   +  S  +  LLD + P+++   +
Sbjct: 856 LMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVS 915

Query: 930 VGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQ 989
           VGDWL AIKM RYK++F +AG+ + + V  +  EDL RIG+T   HQ KILSS+Q MR Q
Sbjct: 916 VGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQ 975

Query: 990 MNQ 992
           M Q
Sbjct: 976 MQQ 978


>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
           sapiens]
          Length = 983

 Score = 1102 bits (2849), Expect = 0.0
 Identities = 549/967 (56%), Positives = 703/967 (72%), Gaps = 21/967 (2%)

Query: 39  EETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIW 98
           E  L+D+K +  EL W S+P  GWEE+SG DE   PIRTYQVCNV + SQNNWLRT ++ 
Sbjct: 29  EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88

Query: 99  RRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVD 158
           R   Q++YVELKFT+RDCNSIP + G+CKETFNL+Y E+D D        + E+ + K+D
Sbjct: 89  RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144

Query: 159 TIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCAS 214
           TIA DESF+++D G    ++NT++R  GP++K GFYLAFQD GAC++L+SVR ++KKC  
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204

Query: 215 TTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATG 274
           T    A+FP+T+   +  SLV   G+C+ N+ E   P ++YC+ +GEW+VP+G C+C  G
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262

Query: 275 HEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADS 334
           +E   +   C+ C PG YKA  G   C  CPP+S T    +  C C NN++RAD D    
Sbjct: 263 YEE--RGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320

Query: 335 ACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDD 394
           ACT  PS PR VISN+NETS+IL+WS P D GGR D+ +N+ICKKC        C  C  
Sbjct: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKC--GWNIKQCEPCSP 378

Query: 395 NVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPS 454
           NV F+PRQ GLT   V ++ LLAHT YTFE+ AVNGVS  S  P ++AAV+ITTNQAAPS
Sbjct: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438

Query: 455 EVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQLDG 512
            V T++   +S +S++LSW  PE PNG+ILDYE+KY+EK E   S   + ++  +V +  
Sbjct: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISS 498

Query: 513 LRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVV 572
           L+PD  YV Q+RART AGYG  SR  EFET+ +  S + +  + + + + +A A ++  V
Sbjct: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTV 558

Query: 573 AV-VVIAIVCLRKQRHGSDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAVREFAKEIDV 630
            + V+I   C  K +HG+D +       ++  PG++ Y+DP TYEDP +AV EFAKE+D 
Sbjct: 559 VIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDA 618

Query: 631 SCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFD 690
           + + I++V+GAGEFGEVC GRLK P ++E+ VAIKTLKVGYTE+QRRDFL EASIMGQFD
Sbjct: 619 TNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFD 678

Query: 691 HPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLS 750
           HPNIIRLEGVVTKS+PVMI+TE+MEN +LDSFLR +D QFTVIQLVGMLRGIA+GMKYLS
Sbjct: 679 HPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLS 738

Query: 751 EMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAI 810
           +M YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDDP +  YT+  GGKIPIRWT+PEAI
Sbjct: 739 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDP-EAAYTTR-GGKIPIRWTSPEAI 796

Query: 811 AYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQL 870
           AYRKFTSASDVWSYGIV+WEVMSYGERPYW+MSNQDVI AV++ YRLPPPMDCP AL+QL
Sbjct: 797 AYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQL 856

Query: 871 MLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTV 930
           MLDCW +DRN RPKF QIV+ LDKLIRN  SLK+I SA +  S  LLD++  D TTF T 
Sbjct: 857 MLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTT 916

Query: 931 GDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQ- 989
           GDWL+ +     KE F    ++S D +A+++ +D+ ++GVT+ G QKKI+SSI+ +  Q 
Sbjct: 917 GDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQS 976

Query: 990 MNQTLPV 996
            N  +PV
Sbjct: 977 KNGPVPV 983


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
          Length = 1015

 Score = 1097 bits (2838), Expect = 0.0
 Identities = 550/988 (55%), Positives = 708/988 (71%), Gaps = 25/988 (2%)

Query: 14   PGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMN 73
            P   PL   LLL   L       + E  L+D++ V  +L W + P++GWEE+   DE   
Sbjct: 35   PRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYA 94

Query: 74   PIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLF 133
            PI TYQVC V E +QNNWL T +I      R+++ELKFT+RDCNS+P   G+CKETFN++
Sbjct: 95   PIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMY 154

Query: 134  YYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGF 189
            Y+E+D            EN Y+K+DTIA DESF+ LD G    ++NT+VR  GPLSK GF
Sbjct: 155  YFESDDQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGF 210

Query: 190  YLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVS 249
            YLAFQD GAC++L+SVR +YKKC S     A+FP+T+TGA+ + L+   G+C+ ++V   
Sbjct: 211  YLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV-TD 269

Query: 250  VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSR 309
             P K++C+ +GEW+VP+G C C  G+E   K   C+ C PG +KA      C  CPP+S 
Sbjct: 270  EPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSY 327

Query: 310  TTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRD 369
            T   A++ C C  +++R +SD    ACT  PS PR  ISNVNETS+ LEW  P D GGR 
Sbjct: 328  THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK 387

Query: 370  DLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVN 429
            D+ Y + CKKC+   G   C  C  +V ++PRQ GL    V +  LLAHT YTFE++AVN
Sbjct: 388  DVSYYIACKKCNSHAGV--CEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVN 445

Query: 430  GVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMK 489
            GVS  SP   +Y +VN+TTNQAAPS V  ++    + +S++LSW  P+RPNG+IL+YE+K
Sbjct: 446  GVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIK 505

Query: 490  YFEKSEGIASTVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGS 548
            YFEK +  + T+  S+  ++  +GL+P + YV Q+RART AGYG +SR  EFETT    +
Sbjct: 506  YFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAA 565

Query: 549  GAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYI------A 602
             + Q   Q+P+I  S T G++ ++AVV+  ++  R+  +    +  E+ + +        
Sbjct: 566  SSDQ--SQIPVIAVSVTVGVI-LLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKL 622

Query: 603  PGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFV 662
            PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE VIGAGEFGEVC GRLK PG+RE+ V
Sbjct: 623  PGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPV 682

Query: 663  AIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSF 722
            AIKTLKVGYTE+QRRDFL EASIMGQFDHPNII LEGVVTKS+PVMI+TE+MEN +LD+F
Sbjct: 683  AIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTF 742

Query: 723  LRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRF 782
            L+ NDGQFTVIQLVGMLRGI+AGMKYLS+M YVHRDLAARNIL+NSNLVCKVSDFGLSR 
Sbjct: 743  LKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRV 802

Query: 783  LEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDM 842
            LEDDP +  YT+  GGKIPIRWTAPEAIA+RKFTSASDVWSYGIVMWEV+SYGERPYW+M
Sbjct: 803  LEDDP-EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEM 860

Query: 843  SNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASL 902
            +NQDVI AVE+ YRLP PMDCP AL+QLMLDCW ++RN RPKF +IVN LDKLIRN +SL
Sbjct: 861  TNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSL 920

Query: 903  KVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTA 962
            K + +A   +S  L + +      + +VG+WL+AIKMGRY E F+  G++S D VAQ+T 
Sbjct: 921  KTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 980

Query: 963  EDLLRIGVTLAGHQKKILSSIQDMRLQM 990
            EDL R+GVTL GHQKKI++S+Q+M++Q+
Sbjct: 981  EDLRRLGVTLVGHQKKIMNSLQEMKVQL 1008


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
          Length = 1037

 Score = 1088 bits (2813), Expect = 0.0
 Identities = 551/1009 (54%), Positives = 705/1009 (69%), Gaps = 45/1009 (4%)

Query: 14   PGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMN 73
            P   PL   LLL   L       + E  L+D++ V  +L W + P++GWEE+   DE   
Sbjct: 35   PRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYA 94

Query: 74   PIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLF 133
            PI TYQVC V E +QNNWL T +I      R+++ELKFT+RDCNS+P   G+CKETFN++
Sbjct: 95   PIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMY 154

Query: 134  YYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGF 189
            Y+E+D            EN Y+K+DTIA DESF+ LD G    ++NT+VR  GPLSK GF
Sbjct: 155  YFESDDQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGF 210

Query: 190  YLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVS 249
            YLAFQD GAC++L+SVR +YKKC S     A+FP+T+TGA+ + L+   G+C+ ++V   
Sbjct: 211  YLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV-TD 269

Query: 250  VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSR 309
             P K++C+ +GEW+VP+G C C  G+E   K   C+ C PG +KA      C  CPP+S 
Sbjct: 270  EPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSY 327

Query: 310  TTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRD 369
            T   A++ C C  +++R +SD    ACT  PS PR  ISNVNETS+ LEW  P D GGR 
Sbjct: 328  THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK 387

Query: 370  DLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVN 429
            D+ Y + CKKC+   G   C  C  +V ++PRQ GL    V +  LLAHT YTFE++AVN
Sbjct: 388  DVSYYIACKKCNSHAGV--CEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVN 445

Query: 430  GVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMK 489
            GVS  SP   +Y +VN+TTNQAAPS V  ++    + +S++LSW  P+RPNG+IL+YE+K
Sbjct: 446  GVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIK 505

Query: 490  YFEKSEGIASTVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGS 548
            YFEK +  + T+  S+  ++  +GL+P + YV Q+RART AGYG +SR  EFETT    +
Sbjct: 506  YFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAA 565

Query: 549  GAQQLQEQLPLIVGSATAGLVFVVAVVVIAIV-------CLR------------------ 583
             + Q   Q+P+I  S T G++ +  V+ + +        C R                  
Sbjct: 566  SSDQ--SQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGY 623

Query: 584  -KQRHGSDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGA 641
             K +   + E       +I  PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE VIGA
Sbjct: 624  SKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGA 683

Query: 642  GEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVV 701
            GEFGEVC GRLK PG+RE+ VAIKTLKVGYTE+QRRDFL EASIMGQFDHPNII LEGVV
Sbjct: 684  GEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVV 743

Query: 702  TKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAA 761
            TKS+PVMI+TE+MEN +LD+FL+ NDGQFTVIQLVGMLRGI+AGMKYLS+M YVHRDLAA
Sbjct: 744  TKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAA 803

Query: 762  RNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDV 821
            RNIL+NSNLVCKVSDFGLSR LEDDP +  YT+  GGKIPIRWTAPEAIA+RKFTSASDV
Sbjct: 804  RNILINSNLVCKVSDFGLSRVLEDDP-EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDV 861

Query: 822  WSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNL 881
            WSYGIVMWEV+SYGERPYW+M+NQDVI AVE+ YRLP PMDCP AL+QLMLDCW ++RN 
Sbjct: 862  WSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNS 921

Query: 882  RPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGR 941
            RPKF +IVN LDKLIRN +SLK + +A   +S  L + +      + +VG+WL+AIKMGR
Sbjct: 922  RPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGR 981

Query: 942  YKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQM 990
            Y E F+  G++S D VAQ+T EDL R+GVTL GHQKKI++S+Q+M++Q+
Sbjct: 982  YTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030


>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
          Length = 998

 Score = 1076 bits (2783), Expect = 0.0
 Identities = 551/969 (56%), Positives = 688/969 (71%), Gaps = 25/969 (2%)

Query: 37  ALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGF 96
           A E  L+D+K   +EL W S P +GWEE+SG DE   PIRTYQVC V E +QNNWLRT +
Sbjct: 30  AKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNW 89

Query: 97  IWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVK 156
           I + + QR++VELKFT+RDCNS+P + G+CKETFNL+YYE D D          EN YVK
Sbjct: 90  ISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIR----ENLYVK 145

Query: 157 VDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKC 212
           +DTIA DESF++ D G    ++NT+VR  GPLSK GFYLAFQD GAC++L+SV+ +YKKC
Sbjct: 146 IDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKC 205

Query: 213 ASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPL-KLYCNGDGEWMVPVGACTC 271
            S     A+FP+T+TG+E +SLV   GTC+ +A E +    +++C+ +GEW+VP+G C C
Sbjct: 206 WSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCIC 265

Query: 272 ATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDS 331
             G++   K   C PC  G YK+   +  C  CP +S +    +S C C + +YRA SD 
Sbjct: 266 KAGYQQ--KGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDP 323

Query: 332 ADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSR 391
              ACT  PS P+ +I N+N+T++ LEWS P D GGR+D+ Y ++CK+C    G   C  
Sbjct: 324 PYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGE--CVP 381

Query: 392 CDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQA 451
           C  N+ ++P+Q GL +  V +  LLAH  YTFEV+AVNGVS  S     +AAV+ITT QA
Sbjct: 382 CGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQA 441

Query: 452 APSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKS--EGIASTVTSQMNSVQ 509
           APS+V  +        S+ LSW  PE PNGVI +YE+KY+EK   E   STV ++  S  
Sbjct: 442 APSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSAS 501

Query: 510 LDGLRPDARYVVQVRARTVAGYGQYSRPAEF----ETTSERGSGAQQLQEQLPLIVGS-- 563
           ++ L+P   YV Q+RA T AGYG YS   +     E T +         EQ P+I+ +  
Sbjct: 502 INNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVV 561

Query: 564 ATAGLVFVVAVVVIAIVCLRKQRHG-SDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAV 621
           A AG + +V +V   I+  R   +  +D E  E+L  +   PG K YIDP TYEDPN AV
Sbjct: 562 AVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAV 621

Query: 622 REFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLS 681
            +FAKE+D SC+KIE VIGAGEFGEVC GRLK PG+R+V VAIKTLKVGYTE+QRRDFL 
Sbjct: 622 HQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLC 681

Query: 682 EASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRG 741
           EASIMGQFDHPN++ LEGVVT+ +PVMI+ EFMEN ALD+FLR +DGQFTVIQLVGMLRG
Sbjct: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRG 741

Query: 742 IAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIP 801
           IAAGM+YL++M YVHRDLAARNILVNSNLVCKVSDFGLSR +EDDP +  YT++ GGKIP
Sbjct: 742 IAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDP-EAVYTTT-GGKIP 799

Query: 802 IRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPM 861
           +RWTAPEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI A+E+ YRLP PM
Sbjct: 800 VRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPM 859

Query: 862 DCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTV 921
           DCP  LHQLMLDCW ++R  RPKF QIV  LDK+IRN  SLK      S    PLLD+  
Sbjct: 860 DCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNT 919

Query: 922 PDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILS 981
           PD+TTF +VG+WL AIKM RYK++F +AG+ S + VA+MT ED++ +G+TL GHQKKI+S
Sbjct: 920 PDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMS 979

Query: 982 SIQDMRLQM 990
           SIQ MR QM
Sbjct: 980 SIQTMRAQM 988


>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
          Length = 1130

 Score = 1035 bits (2677), Expect = 0.0
 Identities = 541/1024 (52%), Positives = 682/1024 (66%), Gaps = 73/1024 (7%)

Query: 26   LPLLLL-PAGCRALEET---LMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVC 81
            LPLL   P  C  +      L+DT  V  EL W ++P +GW+ ++  DE   PI TYQVC
Sbjct: 111  LPLLTAWPGDCSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVC 170

Query: 82   NVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDV 141
            NV E +QNNWLRT +I R   Q++YVE+KFT+RDCNSIP + G+CKETFNLFY E+D   
Sbjct: 171  NVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESH 230

Query: 142  ASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQG 197
                 P    N Y K+DTIA DESF+++D G    ++NT++R  GP+ + GFYLAFQD G
Sbjct: 231  GIKFKP----NQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIG 286

Query: 198  ACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCN 257
            AC++L+SVR FYKKC  T    A+FP+T+   + +SLV   G+C+ +A E   P KLYC 
Sbjct: 287  ACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTP-KLYCG 345

Query: 258  GDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASI 317
             DG+W+VP+G C C+TG+E    E  C  C PG YKA  G   C  CPP+S T   A S+
Sbjct: 346  ADGDWLVPLGRCICSTGYEEI--EGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSV 403

Query: 318  CTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVIC 377
            C C   ++RA+ D    ACT  PS PR V+ N+NET+LILEWS P D GGR DL Y+VIC
Sbjct: 404  CQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVIC 463

Query: 378  KKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPL 437
            KKC      S C  C   + F+PR  GL    V +   ++H  YTFE++A+NGVS  S  
Sbjct: 464  KKC--GLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFS 521

Query: 438  PPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEG- 496
            P  + A+ +TT+Q APS +  +R   +S +S+ LSW  P   NG ILDYE+KY+EK    
Sbjct: 522  PKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQ 581

Query: 497  -IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQE 555
               S+  S+  SV + GL+P  +YV  +R RT  GY  YS+  EFET  E    A + Q 
Sbjct: 582  LTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAE-QG 640

Query: 556  QLPLIVGSATAGLVFVVAVVVIAIVCLRKQRH-GSDSEYTEKLQQYIA------PGMKVY 608
            Q+ +I  +A  G   +V + +  ++  R Q +  +  +  EK + ++       PG+K Y
Sbjct: 641  QILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTY 700

Query: 609  IDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLK 668
            IDP TYEDP+ AV EFAKEID S ++IE VIGAGEFGEVC GRLK PG+RE+ VAIKTLK
Sbjct: 701  IDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLK 760

Query: 669  VGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTK------------------------- 703
             G+ +RQRRDFL EASIMGQFDHPNIIRLEGVVTK                         
Sbjct: 761  GGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQ 820

Query: 704  -----------------SRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746
                              RPVMI+ E+MEN +LDSFLR +DG FTVIQLVGMLRGIA+GM
Sbjct: 821  APHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGM 880

Query: 747  KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806
            KYLS+M YVHRDLAARNILVNSNLVCKVSDFGLSR LEDDP +  YT++ GGKIPIRWTA
Sbjct: 881  KYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EAAYTTT-GGKIPIRWTA 938

Query: 807  PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTA 866
            PEAIAYRKF+SASD WSYGIVMWEVMSYGERPYW+MSNQDVI ++E+ YRLP PM CP +
Sbjct: 939  PEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPAS 998

Query: 867  LHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTT 926
            LHQLML CW ++RN RPKF+ IV+ LDKLIRN ++L  +   +  +  P     VP+Y  
Sbjct: 999  LHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTL--VEDILVMPESPGEVPEYPL 1056

Query: 927  FTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDM 986
            F TVGDWLD+IKMG+YK +FV+AGF +FDL+++M+ +D+ RIGV L GHQ++I+SSIQ +
Sbjct: 1057 FVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTL 1116

Query: 987  RLQM 990
            RL M
Sbjct: 1117 RLHM 1120


>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
           sapiens]
          Length = 1005

 Score =  991 bits (2562), Expect = 0.0
 Identities = 514/1020 (50%), Positives = 688/1020 (67%), Gaps = 60/1020 (5%)

Query: 11  SPPPGLLPLLPPLLLLPLLLLPAGCRAL---EETLMDTKWVTSELAWTSHPESGWEEVSG 67
           +P  G LP  P L ++      A C +    E  L+DT  +  +  W ++P  GW+ ++ 
Sbjct: 2   APARGRLP--PALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINE 59

Query: 68  YDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCK 127
            DE+  PI TYQVCNV   +QNNWLRT ++ R   +RVY E+KFT+RDCNS+P + G+CK
Sbjct: 60  VDESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCK 119

Query: 128 ETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGP 183
           ETFNL+Y E+D D+ +++     E+ ++K+DTIA DESF+  D G    ++NT+VRS GP
Sbjct: 120 ETFNLYYLESDRDLGASTQ----ESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGP 175

Query: 184 LSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIP 243
           LSK GFYLAFQD GAC++++S+R +YKKC +     A F E +TGA+ +SLV   G C+ 
Sbjct: 176 LSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVR 235

Query: 244 NAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLP 303
           ++ E   P K+YC+ +GEW+VP+G C C+ G+E   +   C  C  G YK+  G+  C  
Sbjct: 236 HSEERDTP-KMYCSAEGEWLVPIGKCVCSAGYEE--RRDACVACELGFYKSAPGDQLCAR 292

Query: 304 CPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPR 363
           CPP+S + +PAA  C C  ++YRA  D   SACT  PS P  +IS+VN TS+ LEW+ P 
Sbjct: 293 CPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPL 352

Query: 364 DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423
           D GGR D+ YN +C++C  A   S C  C     FVP+Q  L +  + +++LLAH  Y+F
Sbjct: 353 DPGGRSDITYNAVCRRCPWA--LSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSF 410

Query: 424 EVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVI 483
            ++AVNGVS  SP P R A VNITTNQAAPS+V  +R   +  +S++L W  PE+PNG+I
Sbjct: 411 WIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGII 470

Query: 484 LDYEMKYFEKSEGIAS--TVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFE 541
           L+YE+KY+EK + + S  T+ +      + GL+P  RYV QVRART AG G++S+  E E
Sbjct: 471 LEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVE 530

Query: 542 TTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRH--------GSDSEY 593
           T      G  + +     IV      L  +  +VV+ ++ + K+RH         SD E 
Sbjct: 531 T------GKPRPRYDTRTIVWIC---LTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEK 581

Query: 594 TEK----------LQQYIAPGM----KVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVI 639
                        L  +  PG     + Y +P TYE+P  A R F +EI+ S + IE++I
Sbjct: 582 MHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKII 641

Query: 640 GAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEG 699
           G+G+ GEVC GRL+ PG+R+V VAIK LK GYTERQRRDFLSEASIMGQFDHPNIIRLEG
Sbjct: 642 GSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEG 701

Query: 700 VVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDL 759
           VVT+ R  MI+TE+MEN +LD+FLR +DGQFT++QLVGMLRG+ AGM+YLS++ YVHRDL
Sbjct: 702 VVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDL 761

Query: 760 AARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSAS 819
           AARN+LV+SNLVCKVSDFGLSR LEDDP D  YT++ GGKIPIRWTAPEAIA+R F+SAS
Sbjct: 762 AARNVLVDSNLVCKVSDFGLSRVLEDDP-DAAYTTT-GGKIPIRWTAPEAIAFRTFSSAS 819

Query: 820 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDR 879
           DVWS+G+VMWEV++YGERPYW+M+N+DVI++VE+ YRLP PM CP ALHQLMLDCW +DR
Sbjct: 820 DVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDR 879

Query: 880 NLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFT------TVGDW 933
             RP+FSQIV+ LD LIR+  SL+  A+  S    P   R+  D    +      TVGDW
Sbjct: 880 AQRPRFSQIVSVLDALIRSPESLRATATV-SRCPPPAFVRSCFDLRGGSGGGGGLTVGDW 938

Query: 934 LDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQT 993
           LD+I+MGRY++ F + G++S  +V +M A+D+  +G+TL GHQKKIL SIQ MR Q+  T
Sbjct: 939 LDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTST 998


>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
          Length = 1021

 Score =  885 bits (2286), Expect = 0.0
 Identities = 471/1018 (46%), Positives = 637/1018 (62%), Gaps = 65/1018 (6%)

Query: 28   LLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRES- 86
            +LLL +   ALEE L+DT   TSE+ W ++P  GW+EVS  D+     RT++ C+V  + 
Sbjct: 22   VLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGAP 81

Query: 87   ---SQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVAS 143
                Q+NWL+T F+ RR  QR ++ L F+VR C+S+    G+C+ETF L+Y +A+   + 
Sbjct: 82   PGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPDSP 141

Query: 144  ASSPFWMENPYVKVDTIAPDESFSRLDAG----------------------RVNTKVRSF 181
             S   W    + KVDTIA DESF    +                       ++N K RSF
Sbjct: 142  DSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSF 201

Query: 182  GPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPET-LTGAEPTSLVIAPGT 240
            GPL++ GFY+AFQD GAC++L++VR F   C +    FA FPET  +GA   SLV A GT
Sbjct: 202  GPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGT 261

Query: 241  CIPNAVEVS---------VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGS 291
            C+ +A              P +L+CNG+G+WMV VG C C  G++PA  +  C+ CP G 
Sbjct: 262  CVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGL 321

Query: 292  YKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVN 351
            YK+  G  PC PCP  S   +PAA +C C   FYRA SD  ++ CT  PS P+ +   V 
Sbjct: 322  YKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQ 381

Query: 352  ETSLILEWSEPRDLGGRDDLLYNVICKKCHG-----AGGASACSRCDDNVEFVPRQLGLT 406
             ++L+L W  PR+LGGR DLL+NV+CK+C G     +GG   C RC D V F PRQ GLT
Sbjct: 382  GSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLT 441

Query: 407  ERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSG 466
            E RV +  L AH  Y  EVQAVNGVS  SP PP+ AA+N++T+   PS VP +   S + 
Sbjct: 442  ESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRAS 501

Query: 467  SSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQLDGLRPDARYVVQVR 524
            +S+T+SW  P++ NG ILDY+++Y++++E  +   T+TS+ N+  +  L P   Y  QVR
Sbjct: 502  NSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVR 561

Query: 525  ARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVV--AVVVIAIVCL 582
            ART AG+G Y     F+T  + G  + QL E+L L++GS    L F++  A+ V+A+V  
Sbjct: 562  ARTAAGHGPYGGKVYFQTLPQ-GELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQ 620

Query: 583  RKQRHGSDSEYTEKLQQYIAPGM--KVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIG 640
            RK+R    + YTE+LQQY +PG+  K YIDP TYEDP +A+RE A+E+D + +KIEEVIG
Sbjct: 621  RKRR---GTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIG 677

Query: 641  AGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGV 700
             G FGEV +GRL+  GRRE  VAI+ L  G  E  +  FL  A+++GQF HPNI+RLEGV
Sbjct: 678  TGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGV 737

Query: 701  VTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLA 760
            VTKSRP+M+LTEFME   LDSFLR  +GQF+ +QLV M RG+AA M+YLS   +VHR L+
Sbjct: 738  VTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLS 797

Query: 761  ARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASD 820
            A ++LVNS+LVCKV+  G S      P  P+          +RW APE IA+ K T++SD
Sbjct: 798  AHSVLVNSHLVCKVARLGHS------PQGPSCL--------LRWAAPEVIAHGKHTTSSD 843

Query: 821  VWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRN 880
            VWS+GI+MWEVMSYGERPYWDMS Q+V+NA+EQ++RLPPP  CP  LH LMLD W +DR 
Sbjct: 844  VWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRA 903

Query: 881  LRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMG 940
             RP F Q+V   DK+IR   +L+         SQ LL     D+    +   WL AI + 
Sbjct: 904  RRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLE 963

Query: 941  RYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV 998
             Y+++F   G  +F  VAQ++ EDL  +G+TLAGHQKK+L  IQ ++  + Q   V+V
Sbjct: 964  CYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV 1021


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score =  875 bits (2260), Expect = 0.0
 Identities = 470/980 (47%), Positives = 626/980 (63%), Gaps = 44/980 (4%)

Query: 29  LLLPAGCRALEETLMDTKWVTSELAWTSHPES-GWEEVSGYDEAMNPIRTYQVCNVRESS 87
           L   A  +  E  L+D      EL W +HP   GW+ +      M PI  Y VCNV    
Sbjct: 18  LAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGD 76

Query: 88  QNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSP 147
           Q+NWLRT +++R + +R+++ELKFTVRDCNS P    SCKETFNL+Y E+D D  +    
Sbjct: 77  QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTN--- 133

Query: 148 FWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLI 203
            + +  + K+DTIAPDE     D      ++N + RS GPL++ GFYLAFQD GAC++L+
Sbjct: 134 -FQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALL 192

Query: 204 SVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPL-----KLYCNG 258
           SVR +YKKC     G A FPET+ G++  SL    GTC+ +AV   VP      +++C  
Sbjct: 193 SVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAV---VPPGGEEPRMHCAV 249

Query: 259 DGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASIC 318
           DGEW+VP+G C C  G+E    E  C+ C PG +K +  E PCL CP ++  +   A+ C
Sbjct: 250 DGEWLVPIGQCLCQAGYEKV--EDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307

Query: 319 TCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICK 378
            C   F+RA  D A   CT  PS P  + +      + L W+ P+D GGR+D++Y+V C+
Sbjct: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367

Query: 379 KCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLP 438
           +C    G   C  C+ +V +     GLT   V +S L  H  YTF V+A NGVSG     
Sbjct: 368 QCWPESGE--CGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT-S 424

Query: 439 PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIA 498
             +   +++ NQ  P   P +RL   S +SL++SW+ P      +  YE+ Y +K +  +
Sbjct: 425 RSFRTASVSINQTEP---PKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNS 481

Query: 499 STVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQL 557
             V  ++  SV LD L PD  Y+VQV+A T  G G  S+  EF+T S  GSG        
Sbjct: 482 YNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLA----- 536

Query: 558 PLIVGSATAGLVFVVAVVVIAIVCLRKQ-----RHGSDSEYTEKLQQYIAPGMKVYIDPF 612
             ++G    G+V ++ +  +     R++     R   +  Y  K +Q + P +K Y+DP 
Sbjct: 537 --VIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQ-LKP-LKTYVDPH 592

Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLK-QPGRREVFVAIKTLKVGY 671
           TYEDPN+AV +F  EI  SCV  ++VIGAGEFGEV +G LK   G++EV VAIKTLK GY
Sbjct: 593 TYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGY 652

Query: 672 TERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFT 731
           TE+QR DFL EA IMGQF H NIIRLEGV++K +P+MI+TE+MEN ALD FLR  DG+F+
Sbjct: 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFS 712

Query: 732 VIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791
           V+QLVGMLRGIAAGMKYL+ MNYVHRDLAARNILVNSNLVCKVSDFGLSR LEDDP + T
Sbjct: 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EAT 771

Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851
           YT+S GGKIPIRWTAPEAI+YRKFTSASDVWS+GIVMWEVM+YGERPYW++SN +V+ A+
Sbjct: 772 YTTS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAI 830

Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSG 911
              +RLP PMDCP+A++QLM+ CW ++R  RPKF+ IV+ LDKLIR   SLK +A     
Sbjct: 831 NDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPR 890

Query: 912 MSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVT 971
           +S  L   +  +   F TV +WL++IKM +Y E F++AG+ + + V QMT +D+ RIGV 
Sbjct: 891 VSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVR 950

Query: 972 LAGHQKKILSSIQDMRLQMN 991
           L GHQK+I  S+  ++ Q+N
Sbjct: 951 LPGHQKRIAYSLLGLKDQVN 970


>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
          Length = 1008

 Score =  803 bits (2073), Expect = 0.0
 Identities = 431/1001 (43%), Positives = 616/1001 (61%), Gaps = 27/1001 (2%)

Query: 12   PPPGLLPLLPPLLLLPLLLLPAGCRALEET-LMDTKWVTSELAWTSHPESGWEEVSGYDE 70
            P P  L L    L L LLL P      EE  L+D+K   +EL WT+ P +GWEE+SG DE
Sbjct: 7    PHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDE 66

Query: 71   AMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETF 130
               PIRTYQVCNV E +Q+NWL+TG+I R   QR++VEL+FT+RDC+SIP   G+CKETF
Sbjct: 67   HDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETF 126

Query: 131  NLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSK 186
            N++Y E ++D+           P  K+DTIA DESF++ D G    ++NT+VR  GPLS+
Sbjct: 127  NVYYLETEADLGRGRPRLGGSRPR-KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSR 185

Query: 187  AGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAV 246
             GF+LAFQD GAC++L+SVR +YK+C +T  G A FP T   +  ++LV   GTC+ ++ 
Sbjct: 186  RGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSE 245

Query: 247  -EVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCP 305
             E   P +++C  DGEW+VPVG C+C+ G +   +   C  CPPG YK       C PCP
Sbjct: 246  GEPGSPPRMHCGADGEWLVPVGRCSCSAGFQE--RGDFCEACPPGFYKVSPRRPLCSPCP 303

Query: 306  PNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILE--WSEPR 363
             +SR    A++ C C +++ R+ +D   ++CT  PS PR +  +++ + L+L   W  P 
Sbjct: 304  EHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPA 363

Query: 364  DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423
            D GGR D+ Y+++C +C   G A AC  C   V F+PRQ GL ER   + HL    RYT 
Sbjct: 364  DSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTV 423

Query: 424  EVQAVNGVSGKSPLP-PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPP---ERP 479
             V A+NGVSG +      YA V ++T   AP E   +R       S++LSW  P     P
Sbjct: 424  RVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAP 483

Query: 480  NGVILDYEMKYFEK--SEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQ---Y 534
                 +YE++Y+EK  SE   S V +   +V +  L+P  RYV Q+RA +     +   +
Sbjct: 484  GANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSF 543

Query: 535  SRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAI---VCLRKQRHGSDS 591
            +   E +T  E  SG++     + + V + +A LV    + V+AI    C   +  G   
Sbjct: 544  NPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAH 603

Query: 592  EYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGR 651
            +  E    +  P  + ++DP +  D  +AV  FAKE+D   V +E  +G G FGE+C G 
Sbjct: 604  DEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGC 663

Query: 652  LKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILT 711
            L+ PGR+E+ VA+  L+   ++ QR  FL+EA  +GQFDH +I+RLEGVVT+   +MI+T
Sbjct: 664  LQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVT 723

Query: 712  EFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLV 771
            E+M + ALD FLR ++GQ    QL+G+L G+A+ MKYLSEM YVHR LAAR++LV+S+LV
Sbjct: 724  EYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLV 783

Query: 772  CKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEV 831
            CK+S FG       D S+  YT+ + G+ P  W APE + +  F+SASDVWS+GI+MWEV
Sbjct: 784  CKISGFGRG---PRDRSEAVYTT-MSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEV 839

Query: 832  MSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNT 891
            M++GERPYWDMS QDVI AVE  +RLPPP +CP  LH+LMLDCW +D   RP+FSQI + 
Sbjct: 840  MAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSI 899

Query: 892  LDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGF 951
            L K++++    K   +       PL DR    + +F +VG WL+A+ + RYK+SF +AG+
Sbjct: 900  LSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGY 959

Query: 952  ASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQ 992
             S + VA+MTA+DL+ +G++LA H++ +LS I  ++ ++ Q
Sbjct: 960  GSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQ 1000


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score =  745 bits (1924), Expect = 0.0
 Identities = 429/987 (43%), Positives = 575/987 (58%), Gaps = 34/987 (3%)

Query: 18  PLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWT-SHPESGWEEVSGYDEAMN--P 74
           PL   L+LL    LP G RA E TLMDT     EL W    P+ GW E     + +N  P
Sbjct: 6   PLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSE---QQQILNGTP 62

Query: 75  IRTYQVCNVR-ESSQNNWLRTGFIWR-RDVQRVYVELKFTVRDCNSIPNIPG--SCKETF 130
           +  YQ C ++     ++WLR+ +I+R  +  RV+VEL+FTVRDC S P   G   CKETF
Sbjct: 63  LYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETF 122

Query: 131 NLFYYEADSDVASASSPFWMENP-YVKVDTIAPDESFSRLD----AGRVNTKVRSFGPLS 185
           NL Y E+D DV        +  P + KV T+A D+SF+  D    + ++N +  S G L+
Sbjct: 123 NLLYMESDQDVG-----IQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLT 177

Query: 186 KAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNA 245
           + G YLAF + GAC++L+SVR FY++C  T  G A FP+TL G  P  LV   GTC+P+A
Sbjct: 178 RRGLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPG--PAGLVEVAGTCLPHA 235

Query: 246 VEVSVPL---KLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCL 302
                P    +++C+ DGEW+VPVG C C  G+E       C  CP GSY+       CL
Sbjct: 236 RASPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCL 295

Query: 303 PCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEP 362
            CP  S   S  A+ICTC +  YRA  +    ACT  PS PR +  + + T L L W  P
Sbjct: 296 TCPQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPP 355

Query: 363 RDLGGRDDLLYNVICKKCHG-AGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRY 421
            D GGR D+ Y+V C +C G A     C  C   V F P   GLT   VH++ L  +  Y
Sbjct: 356 ADTGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANY 415

Query: 422 TFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPE-RPN 480
           TF V+A NGVSG         +V+I+   A      +LRL       L L+WA    R  
Sbjct: 416 TFNVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP 475

Query: 481 GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF 540
           G  L YE+    + E     V      V L  L+PD  Y+V+VR  T  G G +S   EF
Sbjct: 476 GANLTYELHVLNQDEERYQMVLEPR--VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEF 533

Query: 541 ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY 600
            T+     G      ++  ++     G   ++ ++V      ++QR     +    + + 
Sbjct: 534 RTSPPVSRGLTG--GEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDRE 591

Query: 601 IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV 660
               +K Y+D   YEDP +   +F +E+D + + ++ VIG GEFGEV RG L+ P +   
Sbjct: 592 DKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCK 651

Query: 661 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD 720
            VAIKTLK      Q  +FL EA+IMGQF HP+I+ LEGVVTK +P+MI+TEFMEN ALD
Sbjct: 652 TVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALD 711

Query: 721 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 780
           +FLR  + Q    QLV ML+GIA+GM YLS  NYVHRDLAARNILVN NL CKVSDFGL+
Sbjct: 712 AFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLT 771

Query: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW 840
           R L+D   D TY +  GGKIPIRWTAPEAIA+R FT+ASDVWS+GIVMWEV+S+G++PY 
Sbjct: 772 RLLDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 828

Query: 841 DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA 900
           +MSNQ+V+ ++E  YRLPPP+DCP  L++LM +CW  DR  RP F ++   L++L+ N  
Sbjct: 829 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 888

Query: 901 SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM 960
           SL+ IA+    M+  L   +  D   + TV +WL++I+M RY   F SAG  + + V ++
Sbjct: 889 SLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLEL 948

Query: 961 TAEDLLRIGVTLAGHQKKILSSIQDMR 987
           TAEDL ++G+TL GHQK+IL SIQ  +
Sbjct: 949 TAEDLTQMGITLPGHQKRILCSIQGFK 975


>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
           sapiens]
          Length = 539

 Score =  535 bits (1379), Expect = e-152
 Identities = 262/513 (51%), Positives = 347/513 (67%), Gaps = 16/513 (3%)

Query: 39  EETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIW 98
           E  L+D+K +  EL W S+P  GWEE+SG DE   PIRTYQVCNV + SQNNWLRT ++ 
Sbjct: 29  EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88

Query: 99  RRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVD 158
           R   Q++YVELKFT+RDCNSIP + G+CKETFNL+Y E+D D        + E+ + K+D
Sbjct: 89  RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDD----HGVKFREHQFTKID 144

Query: 159 TIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCAS 214
           TIA DESF+++D G    ++NT++R  GP++K GFYLAFQD GAC++L+SVR ++KKC  
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204

Query: 215 TTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATG 274
           T    A+FP+T+   +  SLV   G+C+ N+ E   P ++YC+ +GEW+VP+G C+C  G
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262

Query: 275 HEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADS 334
           +E   +   C+ C PG YKA  G   C  CPP+S T    +  C C NN++RAD D    
Sbjct: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320

Query: 335 ACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDD 394
           ACT  PS PR VISN+NETS+IL+WS P D GGR D+ +N+ICKKC        C  C  
Sbjct: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKC--GWNIKQCEPCSP 378

Query: 395 NVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPS 454
           NV F+PRQ GLT   V ++ LLAHT YTFE+ AVNGVS  S  P ++AAV+ITTNQAAPS
Sbjct: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438

Query: 455 EVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQLDG 512
            V T++   +S +S++LSW  PE PNG+ILDYE+KY+EK E   S   + ++  +V +  
Sbjct: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISS 498

Query: 513 LRPDARYVVQVRARTVAGYGQYSRPAEFETTSE 545
           L+PD  YV Q+RART AGYG  SR  EFET+ +
Sbjct: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531


>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
           sapiens]
          Length = 495

 Score =  414 bits (1065), Expect = e-115
 Identities = 205/448 (45%), Positives = 286/448 (63%), Gaps = 18/448 (4%)

Query: 11  SPPPGLLPLLPPLLLLPLLLLPAGCRAL---EETLMDTKWVTSELAWTSHPESGWEEVSG 67
           +P  G LP  P L ++      A C +    E  L+DT  +  +  W ++P  GW+ ++ 
Sbjct: 2   APARGRLP--PALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINE 59

Query: 68  YDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCK 127
            DE+  PI TYQVCNV   +QNNWLRT ++ R   +RVY E+KFT+RDCNS+P + G+CK
Sbjct: 60  VDESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCK 119

Query: 128 ETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGP 183
           ETFNL+Y E+D D+ +++     E+ ++K+DTIA DESF+  D G    ++NT+VRS GP
Sbjct: 120 ETFNLYYLESDRDLGAST----QESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGP 175

Query: 184 LSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIP 243
           LSK GFYLAFQD GAC++++S+R +YKKC +     A F E +TGA+ +SLV   G C+ 
Sbjct: 176 LSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVR 235

Query: 244 NAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLP 303
           ++ E   P K+YC+ +GEW+VP+G C C+ G+E   +   C  C  G YK+  G+  C  
Sbjct: 236 HSEERDTP-KMYCSAEGEWLVPIGKCVCSAGYE--ERRDACVACELGFYKSAPGDQLCAR 292

Query: 304 CPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPR 363
           CPP+S + +PAA  C C  ++YRA  D   SACT  PS P  +IS+VN TS+ LEW+ P 
Sbjct: 293 CPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPL 352

Query: 364 DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423
           D GGR D+ YN +C++C  A   S C  C     FVP+Q  L +  + +++LLAH  Y+F
Sbjct: 353 DPGGRSDITYNAVCRRCPWA--LSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSF 410

Query: 424 EVQAVNGVSGKSPLPPRYAAVNITTNQA 451
            ++AVNGVS  SP P R A VNITTNQA
Sbjct: 411 WIEAVNGVSDLSPEPRRAAVVNITTNQA 438



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 13/29 (44%), Positives = 17/29 (58%)

Query: 453 PSEVPTLRLHSSSGSSLTLSWAPPERPNG 481
           P   P   + S +G+S+TL WAPP  P G
Sbjct: 328 PPSAPVNLISSVNGTSVTLEWAPPLDPGG 356


>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
          Length = 295

 Score =  255 bits (651), Expect = 2e-67
 Identities = 132/271 (48%), Positives = 180/271 (66%), Gaps = 7/271 (2%)

Query: 12  PPPGLLPLLPPLLLLPLLLLPAGCRALEET-LMDTKWVTSELAWTSHPESGWEEVSGYDE 70
           P P  L L    L L LLL P      EE  L+D+K   +EL WT+ P +GWEE+SG DE
Sbjct: 7   PHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDE 66

Query: 71  AMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETF 130
              PIRTYQVCNV E +Q+NWL+TG+I R   QR++VEL+FT+RDC+SIP   G+CKETF
Sbjct: 67  HDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETF 126

Query: 131 NLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSK 186
           N++Y E ++D+           P  K+DTIA DESF++ D G    ++NT+VR  GPLS+
Sbjct: 127 NVYYLETEADLGRGRPRLGGSRPR-KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSR 185

Query: 187 AGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAV 246
            GF+LAFQD GAC++L+SVR +YK+C +T  G A FP T   +  ++LV   GTC+ ++ 
Sbjct: 186 RGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSE 245

Query: 247 -EVSVPLKLYCNGDGEWMVPVGACTCATGHE 276
            E   P +++C  DGEW+VPVG C+C+ G +
Sbjct: 246 GEPGSPPRMHCGADGEWLVPVGRCSCSAGFQ 276


>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
          Length = 526

 Score =  219 bits (557), Expect = 1e-56
 Identities = 118/284 (41%), Positives = 175/284 (61%), Gaps = 12/284 (4%)

Query: 611 PFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVG 670
           P     P +   + A EI    +K+E+ +GAG+FGEV      +  +    VA+KT+K G
Sbjct: 240 PCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTK----VAVKTMKPG 295

Query: 671 YTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQF 730
               +   FL+EA++M    H  +++L  VVTK  P+ I+TEFM   +L  FL+ ++G  
Sbjct: 296 SMSVEA--FLAEANVMKTLQHDKLVKLHAVVTKE-PIYIITEFMAKGSLLDFLKSDEGSK 352

Query: 731 TVI-QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSD 789
             + +L+     IA GM ++ + NY+HRDL A NILV+++LVCK++DFGL+R +ED+   
Sbjct: 353 QPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE-- 410

Query: 790 PTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIN 849
             YT+  G K PI+WTAPEAI +  FT  SDVWS+GI++ E+++YG  PY  MSN +VI 
Sbjct: 411 --YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIR 468

Query: 850 AVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893
           A+E+ YR+P P +CP  L+ +M+ CW      RP F  I + LD
Sbjct: 469 ALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512


>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
          Length = 1074

 Score =  218 bits (556), Expect = 2e-56
 Identities = 111/270 (41%), Positives = 165/270 (61%), Gaps = 5/270 (1%)

Query: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIM 686
           EI    +++   IG G+FG+V +G    P    + VAIKT K   ++  R  FL EA  M
Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 497

Query: 687 GQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746
            QFDHP+I++L GV+T++ PV I+ E      L SFL++      +  L+     ++  +
Sbjct: 498 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 556

Query: 747 KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806
            YL    +VHRD+AARN+LV+SN   K+ DFGLSR++ED     TY  +  GK+PI+W A
Sbjct: 557 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS----TYYKASKGKLPIKWMA 612

Query: 807 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTA 866
           PE+I +R+FTSASDVW +G+ MWE++ +G +P+  + N DVI  +E   RLP P +CP  
Sbjct: 613 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 672

Query: 867 LHQLMLDCWVRDRNLRPKFSQIVNTLDKLI 896
           L+ LM  CW  D + RP+F+++   L  ++
Sbjct: 673 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 702


>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
          Length = 1052

 Score =  218 bits (556), Expect = 2e-56
 Identities = 111/270 (41%), Positives = 165/270 (61%), Gaps = 5/270 (1%)

Query: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIM 686
           EI    +++   IG G+FG+V +G    P    + VAIKT K   ++  R  FL EA  M
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475

Query: 687 GQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746
            QFDHP+I++L GV+T++ PV I+ E      L SFL++      +  L+     ++  +
Sbjct: 476 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534

Query: 747 KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806
            YL    +VHRD+AARN+LV+SN   K+ DFGLSR++ED     TY  +  GK+PI+W A
Sbjct: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS----TYYKASKGKLPIKWMA 590

Query: 807 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTA 866
           PE+I +R+FTSASDVW +G+ MWE++ +G +P+  + N DVI  +E   RLP P +CP  
Sbjct: 591 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 650

Query: 867 LHQLMLDCWVRDRNLRPKFSQIVNTLDKLI 896
           L+ LM  CW  D + RP+F+++   L  ++
Sbjct: 651 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680


>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
          Length = 543

 Score =  216 bits (551), Expect = 7e-56
 Identities = 123/282 (43%), Positives = 171/282 (60%), Gaps = 12/282 (4%)

Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672
           T +   + + + A EI    +++E  +G G FGEV  G      +    VAIKTLK G  
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312

Query: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732
             +   FL EA IM +  H  ++ L  VV++  P+ I+TEFM   +L  FL+  DG++  
Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSEE-PIYIVTEFMSKGSLLDFLKEGDGKYLK 369

Query: 733 I-QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791
           + QLV M   IA GM Y+  MNY+HRDL A NILV  NLVCK++DFGL+R +ED+     
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---- 425

Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851
           YT+  G K PI+WTAPEA  Y +FT  SDVWS+GI+  E+++ G  PY  M N++V+  V
Sbjct: 426 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQV 485

Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893
           E+ YR+P P  CP +LH+LM  CW +D + RP F  I + L+
Sbjct: 486 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527


>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
            sapiens]
          Length = 1367

 Score =  215 bits (548), Expect = 1e-55
 Identities = 151/505 (29%), Positives = 249/505 (49%), Gaps = 42/505 (8%)

Query: 407  ERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVP-TLRLHSSS 465
            + R  IS+L   T Y  ++ + N  + K            T       ++P  +      
Sbjct: 785  KERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRP 844

Query: 466  GSSLTLSWAPPERPNGVILDYEMKYFEKSEGIASTVTSQ----MNSVQLDGLRPDARYVV 521
             +S+ L W  PE PNG+IL YE+KY  + E     V+ Q        +L+ L P   Y  
Sbjct: 845  ENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNP-GNYTA 903

Query: 522  QVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVC 581
            +++A +++G G ++ P  F   ++ G      +  + LI+    A L+ V  +V++  V 
Sbjct: 904  RIQATSLSGNGSWTDPVFFYVQAKTG-----YENFIHLIIALPVAVLLIVGGLVIMLYVF 958

Query: 582  LRKQ---RHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEV 638
             RK+   R G+   Y     +Y +    VY+      D  E  RE         + +   
Sbjct: 959  HRKRNNSRLGNGVLYASVNPEYFSAA-DVYVP-----DEWEVAREK--------ITMSRE 1004

Query: 639  IGAGEFGEVCRGRLKQ--PGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIR 696
            +G G FG V  G  K       E  VAIKT+    + R+R +FL+EAS+M +F+  +++R
Sbjct: 1005 LGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVR 1064

Query: 697  LEGVVTKSRPVMILTEFMENCALDSFLRLNDGQF---------TVIQLVGMLRGIAAGMK 747
            L GVV++ +P +++ E M    L S+LR    +          ++ +++ M   IA GM 
Sbjct: 1065 LLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMA 1124

Query: 748  YLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAP 807
            YL+   +VHRDLAARN +V  +   K+ DFG++R   D      Y     G +P+RW +P
Sbjct: 1125 YLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTR---DIYETDYYRKGGKGLLPVRWMSP 1181

Query: 808  EAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTAL 867
            E++    FT+ SDVWS+G+V+WE+ +  E+PY  +SN+ V+  V +   L  P +CP  L
Sbjct: 1182 ESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDML 1241

Query: 868  HQLMLDCWVRDRNLRPKFSQIVNTL 892
             +LM  CW  +  +RP F +I++++
Sbjct: 1242 FELMRMCWQYNPKMRPSFLEIISSI 1266



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 12/153 (7%)

Query: 348 SNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAG-----GASACSRCDDN---VEFV 399
           +  ++  +I+ W   R    RD + + V  K+          G  AC     N   V+  
Sbjct: 498 TTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLP 557

Query: 400 PRQLGLTERRVHISHLLAHTRYTFEVQAVN--GVSGKSPLPPRYAAVNITTNQAAPSEVP 457
           P +    E  + +  L   T+Y   V+AV    V        +   + I TN + PS   
Sbjct: 558 PNKD--VEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPL 615

Query: 458 TLRLHSSSGSSLTLSWAPPERPNGVILDYEMKY 490
            +   S+S S L + W PP  PNG +  Y +++
Sbjct: 616 DVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRW 648


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score =  214 bits (546), Expect = 2e-55
 Identities = 114/268 (42%), Positives = 169/268 (63%), Gaps = 12/268 (4%)

Query: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIM 686
           EI    +++ + +G G+FGEV  G      +    VAIKTLK G    +   FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318

Query: 687 GQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVI-QLVGMLRGIAAG 745
            +  H  +++L  VV++  P+ I+TE+M   +L  FL+  +G+   +  LV M   +AAG
Sbjct: 319 KKLKHDKLVQLYAVVSEE-PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377

Query: 746 MKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWT 805
           M Y+  MNY+HRDL + NILV + L+CK++DFGL+R +ED+     YT+  G K PI+WT
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE----YTARQGAKFPIKWT 433

Query: 806 APEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPT 865
           APEA  Y +FT  SDVWS+GI++ E+++ G  PY  M+N++V+  VE+ YR+P P DCP 
Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 493

Query: 866 ALHQLMLDCWVRDRNLRPKFSQIVNTLD 893
           +LH+LM+ CW +D   RP F  + + L+
Sbjct: 494 SLHELMIHCWKKDPEERPTFEYLQSFLE 521


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  214 bits (544), Expect = 4e-55
 Identities = 120/277 (43%), Positives = 169/277 (61%), Gaps = 12/277 (4%)

Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672
           T +   + + + A EI    +++E  +G G FGEV  G      R    VAIKTLK G  
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305

Query: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732
             +   FL EA +M +  H  +++L  VV++  P+ I+TE+M   +L  FL+   G++  
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSEE-PIYIVTEYMSKGSLLDFLKGETGKYLR 362

Query: 733 I-QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791
           + QLV M   IA+GM Y+  MNYVHRDL A NILV  NLVCKV+DFGL+R +ED+     
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---- 418

Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851
           YT+  G K PI+WTAPEA  Y +FT  SDVWS+GI++ E+ + G  PY  M N++V++ V
Sbjct: 419 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV 478

Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQI 888
           E+ YR+P P +CP +LH LM  CW ++   RP F  +
Sbjct: 479 ERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYL 515


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  214 bits (544), Expect = 4e-55
 Identities = 120/277 (43%), Positives = 169/277 (61%), Gaps = 12/277 (4%)

Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672
           T +   + + + A EI    +++E  +G G FGEV  G      R    VAIKTLK G  
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305

Query: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732
             +   FL EA +M +  H  +++L  VV++  P+ I+TE+M   +L  FL+   G++  
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSEE-PIYIVTEYMSKGSLLDFLKGETGKYLR 362

Query: 733 I-QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791
           + QLV M   IA+GM Y+  MNYVHRDL A NILV  NLVCKV+DFGL+R +ED+     
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---- 418

Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851
           YT+  G K PI+WTAPEA  Y +FT  SDVWS+GI++ E+ + G  PY  M N++V++ V
Sbjct: 419 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV 478

Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQI 888
           E+ YR+P P +CP +LH LM  CW ++   RP F  +
Sbjct: 479 ERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYL 515


>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform B [Homo sapiens]
          Length = 491

 Score =  212 bits (540), Expect = 1e-54
 Identities = 112/270 (41%), Positives = 166/270 (61%), Gaps = 11/270 (4%)

Query: 625 AKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEAS 684
           A EI    +K+ + +GAG+FGEV  G      +    VA+KTLK G    Q   FL EA+
Sbjct: 218 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 271

Query: 685 IMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVI-QLVGMLRGIA 743
           +M    H  ++RL  VVT+  P+ I+TE+M   +L  FL+ ++G   ++ +L+     IA
Sbjct: 272 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 331

Query: 744 AGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIR 803
            GM Y+   NY+HRDL A N+LV+ +L+CK++DFGL+R +ED+     YT+  G K PI+
Sbjct: 332 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE----YTAREGAKFPIK 387

Query: 804 WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDC 863
           WTAPEAI +  FT  SDVWS+GI+++E+++YG+ PY   +N DV+ A+ Q YR+P   +C
Sbjct: 388 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 447

Query: 864 PTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893
           P  L+ +M  CW      RP F  + + LD
Sbjct: 448 PDELYDIMKMCWKEKAEERPTFDYLQSVLD 477


>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform A [Homo sapiens]
          Length = 512

 Score =  212 bits (540), Expect = 1e-54
 Identities = 112/270 (41%), Positives = 166/270 (61%), Gaps = 11/270 (4%)

Query: 625 AKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEAS 684
           A EI    +K+ + +GAG+FGEV  G      +    VA+KTLK G    Q   FL EA+
Sbjct: 239 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 292

Query: 685 IMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVI-QLVGMLRGIA 743
           +M    H  ++RL  VVT+  P+ I+TE+M   +L  FL+ ++G   ++ +L+     IA
Sbjct: 293 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 352

Query: 744 AGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIR 803
            GM Y+   NY+HRDL A N+LV+ +L+CK++DFGL+R +ED+     YT+  G K PI+
Sbjct: 353 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE----YTAREGAKFPIK 408

Query: 804 WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDC 863
           WTAPEAI +  FT  SDVWS+GI+++E+++YG+ PY   +N DV+ A+ Q YR+P   +C
Sbjct: 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 468

Query: 864 PTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893
           P  L+ +M  CW      RP F  + + LD
Sbjct: 469 PDELYDIMKMCWKEKAEERPTFDYLQSVLD 498


>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  211 bits (538), Expect = 2e-54
 Identities = 119/284 (41%), Positives = 172/284 (60%), Gaps = 12/284 (4%)

Query: 611 PFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVG 670
           P   + P +   E   E+    +K+ E +GAG+FGEV  G      +    VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278

Query: 671 YTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDG-Q 729
                   FL+EA++M Q  H  ++RL  VVT+  P+ I+TE+MEN +L  FL+   G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYMENGSLVDFLKTPSGIK 335

Query: 730 FTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSD 789
            T+ +L+ M   IA GM ++ E NY+HRDL A NILV+  L CK++DFGL+R +ED+   
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393

Query: 790 PTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIN 849
             YT+  G K PI+WTAPEAI Y  FT  SDVWS+GI++ E++++G  PY  M+N +VI 
Sbjct: 394 --YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451

Query: 850 AVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893
            +E+ YR+  P +CP  L+QLM  CW      RP F  + + L+
Sbjct: 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,577,735
Number of Sequences: 37866
Number of extensions: 2036204
Number of successful extensions: 18096
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 672
Number of HSP's successfully gapped in prelim test: 414
Number of HSP's that attempted gapping in prelim test: 12818
Number of HSP's gapped (non-prelim): 3691
length of query: 998
length of database: 18,247,518
effective HSP length: 112
effective length of query: 886
effective length of database: 14,006,526
effective search space: 12409782036
effective search space used: 12409782036
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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