BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] (998 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 2029 0.0 gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 1412 0.0 gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 1409 0.0 gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 1408 0.0 gi|32528301 EPH receptor B4 precursor [Homo sapiens] 1143 0.0 gi|4758280 ephrin receptor EphA4 [Homo sapiens] 1130 0.0 gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 1102 0.0 gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 1097 0.0 gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 1088 0.0 gi|4758282 ephrin receptor EphA7 [Homo sapiens] 1076 0.0 gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 1035 0.0 gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 991 0.0 gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 885 0.0 gi|32967311 ephrin receptor EphA2 [Homo sapiens] 875 0.0 gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 803 0.0 gi|221316650 ephrin receptor EphA1 [Homo sapiens] 745 0.0 gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 535 e-152 gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 414 e-115 gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 255 2e-67 gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 219 1e-56 gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 218 2e-56 gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 218 2e-56 gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 216 7e-56 gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 215 1e-55 gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 214 2e-55 gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 214 4e-55 gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi... 214 4e-55 gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 212 1e-54 gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... 212 1e-54 gi|112789548 lymphocyte-specific protein tyrosine kinase precurs... 211 2e-54 >gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] Length = 998 Score = 2029 bits (5256), Expect = 0.0 Identities = 998/998 (100%), Positives = 998/998 (100%) Query: 1 MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES 60 MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES Sbjct: 1 MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPES 60 Query: 61 GWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIP 120 GWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIP Sbjct: 61 GWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIP 120 Query: 121 NIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRS 180 NIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRS Sbjct: 121 NIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRS 180 Query: 181 FGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGT 240 FGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGT Sbjct: 181 FGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGT 240 Query: 241 CIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP 300 CIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP Sbjct: 241 CIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGP 300 Query: 301 CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWS 360 CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWS Sbjct: 301 CLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWS 360 Query: 361 EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR 420 EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR Sbjct: 361 EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR 420 Query: 421 YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPN 480 YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPN Sbjct: 421 YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPN 480 Query: 481 GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF 540 GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF Sbjct: 481 GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF 540 Query: 541 ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY 600 ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY Sbjct: 541 ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY 600 Query: 601 IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV 660 IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV Sbjct: 601 IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV 660 Query: 661 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD 720 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD Sbjct: 661 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD 720 Query: 721 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 780 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS Sbjct: 721 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 780 Query: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW 840 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW Sbjct: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW 840 Query: 841 DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA 900 DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA Sbjct: 841 DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA 900 Query: 901 SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM 960 SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM Sbjct: 901 SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM 960 Query: 961 TAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV 998 TAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV Sbjct: 961 TAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV 998 >gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sapiens] Length = 986 Score = 1412 bits (3656), Expect = 0.0 Identities = 694/986 (70%), Positives = 809/986 (82%), Gaps = 19/986 (1%) Query: 23 LLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCN 82 LLLLPLL A+EETLMD+ T+EL W HP SGWEEVSGYDE MN IRTYQVCN Sbjct: 10 LLLLPLLA------AVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCN 63 Query: 83 VRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVA 142 V ESSQNNWLRT FI RR R++VE+KF+VRDC+SIP++PGSCKETFNL+YYEAD D A Sbjct: 64 VFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSA 123 Query: 143 SASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGA 198 + + P WMENP+VKVDTIA DESFS++D G ++NT+VRSFGP+S++GFYLAFQD G Sbjct: 124 TKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGG 183 Query: 199 CMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNG 258 CMSLI+VR FY+KC A+F ETL+GAE TSLV A G+CI NA EV VP+KLYCNG Sbjct: 184 CMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNG 243 Query: 259 DGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASIC 318 DGEW+VP+G C C G E + CR CP G++KA QG+ C CP NSRTTS A+ C Sbjct: 244 DGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNC 303 Query: 319 TCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICK 378 C N +YRAD D D CTT+PS P+ VIS+VNETSL+LEW+ PRD GGR+DL+YN+ICK Sbjct: 304 VCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICK 363 Query: 379 KCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLP 438 C G AC+RC DNV++ PRQLGLTE R++IS LLAHT+YTFE+QAVNGV+ +SP Sbjct: 364 SC--GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFS 421 Query: 439 PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK--SEG 496 P++A+VNITTNQAAPS V + S + S+TLSW+ P++PNGVILDYE++Y+EK SE Sbjct: 422 PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEY 481 Query: 497 IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQ 556 A+ + S N+V + GL+ A YV QVRARTVAGYG+YS F+T +E +QE+ Sbjct: 482 NATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTE-AEYQTSIQEK 540 Query: 557 LPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY----IAPGMKVYIDPF 612 LPLI+GS+ AGLVF++AVVVIAIVC R+ +DSEYT+KLQ Y + PGMK+YIDPF Sbjct: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPF 600 Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672 TYEDPNEAVREFAKEID+SCVKIE+VIGAGEFGEVC G LK PG+RE+FVAIKTLK GYT Sbjct: 601 TYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYT 660 Query: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732 E+QRRDFLSEASIMGQFDHPN+I LEGVVTKS PVMI+TEFMEN +LDSFLR NDGQFTV Sbjct: 661 EKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTV 720 Query: 733 IQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTY 792 IQLVGMLRGIAAGMKYL++MNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDD SDPTY Sbjct: 721 IQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTY 780 Query: 793 TSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVE 852 TS+LGGKIPIRWTAPEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVINA+E Sbjct: 781 TSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIE 840 Query: 853 QDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGM 912 QDYRLPPPMDCP+ALHQLMLDCW +DRN RPKF QIVNTLDK+IRN SLK +A SG+ Sbjct: 841 QDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGI 900 Query: 913 SQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTL 972 + PLLDRT+PDYT+F TV +WL+AIKMG+YKESF +AGF SFD+V+QM ED+LR+GVTL Sbjct: 901 NLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTL 960 Query: 973 AGHQKKILSSIQDMRLQMNQTLPVQV 998 AGHQKKIL+SIQ MR QMNQ V+V Sbjct: 961 AGHQKKILNSIQVMRAQMNQIQSVEV 986 >gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapiens] Length = 987 Score = 1409 bits (3648), Expect = 0.0 Identities = 694/987 (70%), Positives = 810/987 (82%), Gaps = 20/987 (2%) Query: 23 LLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCN 82 LLLLPLL A+EETLMD+ T+EL W HP SGWEEVSGYDE MN IRTYQVCN Sbjct: 10 LLLLPLLA------AVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCN 63 Query: 83 VRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVA 142 V ESSQNNWLRT FI RR R++VE+KF+VRDC+SIP++PGSCKETFNL+YYEAD D A Sbjct: 64 VFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSA 123 Query: 143 SASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGA 198 + + P WMENP+VKVDTIA DESFS++D G ++NT+VRSFGP+S++GFYLAFQD G Sbjct: 124 TKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGG 183 Query: 199 CMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNG 258 CMSLI+VR FY+KC A+F ETL+GAE TSLV A G+CI NA EV VP+KLYCNG Sbjct: 184 CMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNG 243 Query: 259 DGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASIC 318 DGEW+VP+G C C G E + CR CP G++KA QG+ C CP NSRTTS A+ C Sbjct: 244 DGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNC 303 Query: 319 TCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICK 378 C N +YRAD D D CTT+PS P+ VIS+VNETSL+LEW+ PRD GGR+DL+YN+ICK Sbjct: 304 VCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICK 363 Query: 379 KCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLP 438 C G AC+RC DNV++ PRQLGLTE R++IS LLAHT+YTFE+QAVNGV+ +SP Sbjct: 364 SC--GSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFS 421 Query: 439 PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK--SEG 496 P++A+VNITTNQAAPS V + S + S+TLSW+ P++PNGVILDYE++Y+EK SE Sbjct: 422 PQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEY 481 Query: 497 IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQ 556 A+ + S N+V + GL+ A YV QVRARTVAGYG+YS F+T +E +QE+ Sbjct: 482 NATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTE-AEYQTSIQEK 540 Query: 557 LPLIVGSATAGLVFVVAVVVIAIVCLRKQR-HGSDSEYTEKLQQY----IAPGMKVYIDP 611 LPLI+GS+ AGLVF++AVVVIAIVC R++ +DSEYT+KLQ Y + PGMK+YIDP Sbjct: 541 LPLIIGSSAAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDP 600 Query: 612 FTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGY 671 FTYEDPNEAVREFAKEID+SCVKIE+VIGAGEFGEVC G LK PG+RE+FVAIKTLK GY Sbjct: 601 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGY 660 Query: 672 TERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFT 731 TE+QRRDFLSEASIMGQFDHPN+I LEGVVTKS PVMI+TEFMEN +LDSFLR NDGQFT Sbjct: 661 TEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT 720 Query: 732 VIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791 VIQLVGMLRGIAAGMKYL++MNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDD SDPT Sbjct: 721 VIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT 780 Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851 YTS+LGGKIPIRWTAPEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVINA+ Sbjct: 781 YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAI 840 Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSG 911 EQDYRLPPPMDCP+ALHQLMLDCW +DRN RPKF QIVNTLDK+IRN SLK +A SG Sbjct: 841 EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSG 900 Query: 912 MSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVT 971 ++ PLLDRT+PDYT+F TV +WL+AIKMG+YKESF +AGF SFD+V+QM ED+LR+GVT Sbjct: 901 INLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVT 960 Query: 972 LAGHQKKILSSIQDMRLQMNQTLPVQV 998 LAGHQKKIL+SIQ MR QMNQ V+V Sbjct: 961 LAGHQKKILNSIQVMRAQMNQIQSVEV 987 >gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] Length = 984 Score = 1408 bits (3645), Expect = 0.0 Identities = 690/978 (70%), Positives = 811/978 (82%), Gaps = 14/978 (1%) Query: 26 LPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRE 85 L LLLL + A+EETLMDT+ T+EL WT++P SGWEEVSGYDE +N IRTYQVCNV E Sbjct: 6 LLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFE 65 Query: 86 SSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASAS 145 +QNNWL T FI RR R+Y E++FTVRDC+S+PN+PGSCKETFNL+YYE DS +A+ Sbjct: 66 PNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKK 125 Query: 146 SPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMS 201 S FW E PY+KVDTIA DESFS++D G +VNT+VRSFGPL++ GFYLAFQD GACMS Sbjct: 126 SAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMS 185 Query: 202 LISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGE 261 L+SVR F+KKC S FA+FPET+TGAE TSLVIA GTCIPNA EV VP+KLYCNGDGE Sbjct: 186 LLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGE 245 Query: 262 WMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCH 321 WMVP+G CTC G+EP + C+ CP G++KA Q C CP NSR+ + A+ ICTC Sbjct: 246 WMVPIGRCTCKPGYEPENSVA-CKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCR 304 Query: 322 NNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCH 381 +YRAD D + ACT+VPS PR VIS VNETS+ILEW PR+ GGRDD+ YN+ICKKC Sbjct: 305 TGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCR 364 Query: 382 GAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRY 441 +CSRCDDNVEFVPRQLGLTE RV IS L AHT YTF++QA+NGVS KSP PP++ Sbjct: 365 A--DRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQH 422 Query: 442 AAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK--SEGIAS 499 +VNITTNQAAPS VP + S++ S+TLSW PE+PNG+ILDYE++Y+EK +E +S Sbjct: 423 VSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSS 482 Query: 500 TVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPL 559 SQ N+ ++DGLRP YVVQVRARTVAGYG++S F+T ++ +L+EQLPL Sbjct: 483 MARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTD-DDYKSELREQLPL 541 Query: 560 IVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYI----APGMKVYIDPFTYE 615 I GSA AG+VFVV++V I+IVC RK+ + ++ Y++KLQ Y +PGMK+YIDPFTYE Sbjct: 542 IAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYE 601 Query: 616 DPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQ 675 DPNEAVREFAKEIDVS VKIEEVIGAGEFGEV +GRLK PG+RE++VAIKTLK GY+E+Q Sbjct: 602 DPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQ 661 Query: 676 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQL 735 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMI+TEFMEN ALDSFLR NDGQFTVIQL Sbjct: 662 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQL 721 Query: 736 VGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSS 795 VGMLRGIAAGMKYL+EMNYVHRDLAARNILVNSNLVCKVSDFGLSR+L+DD SDPTYTSS Sbjct: 722 VGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781 Query: 796 LGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDY 855 LGGKIP+RWTAPEAIAYRKFTSASDVWSYGIVMWEVMS+GERPYWDMSNQDVINA+EQDY Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDY 841 Query: 856 RLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQP 915 RLPPPMDCP ALHQLMLDCW +DRN RP+F++IVNTLDK+IRN ASLK +A+ + SQP Sbjct: 842 RLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQP 901 Query: 916 LLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGH 975 LLDR++PD+T FTTV DWL AIKM +Y++SF++AGF S LV QMT+EDLLRIG+TLAGH Sbjct: 902 LLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGH 961 Query: 976 QKKILSSIQDMRLQMNQT 993 QKKIL+SI MR+Q++Q+ Sbjct: 962 QKKILNSIHSMRVQISQS 979 >gi|32528301 EPH receptor B4 precursor [Homo sapiens] Length = 987 Score = 1143 bits (2956), Expect = 0.0 Identities = 582/973 (59%), Positives = 718/973 (73%), Gaps = 24/973 (2%) Query: 37 ALEETLMDTKWVTSELAWTSHPE--SGWEEVSGYDEAMNPIRTYQVCNV-RESSQNNWLR 93 ALEETL++TK T++L W + P+ WEE+SG DE + +RTY+VC+V R Q +WLR Sbjct: 15 ALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLR 74 Query: 94 TGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENP 153 TG++ RR VY L+FT+ +C S+P SCKETF +FYYE+D+D A+A +P WMENP Sbjct: 75 TGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENP 134 Query: 154 YVKVDTIAPDESFSRLDA----GRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFY 209 Y+KVDT+A + + G+VN K GPLSKAGFYLAFQDQGACM+L+S+ FY Sbjct: 135 YIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFY 194 Query: 210 KKCASTTAGFALFPETLTGAEPTSLVI-APGTCIPNAVEVSVPL-KLYCNGDGEWMV-PV 266 KKCA T FPET+ P LV+ G+C+ +AV P LYC DG+W PV Sbjct: 195 KKCAQLTVNLTRFPETV----PRELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPV 250 Query: 267 GACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYR 326 C+CA G E A ++CR C G++K GEG C PCP NS + + +++C C ++R Sbjct: 251 TGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFR 310 Query: 327 ADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGA 386 A +D + CTT PS PR V+S +N +SL LEWS P + GGR+DL Y + C++C G Sbjct: 311 ARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGG-- 368 Query: 387 SACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNI 446 +C+ C ++ F P L E V + L YTFEV A+NGVS + P + VN+ Sbjct: 369 -SCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNV 427 Query: 447 TTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK-SEGIAST--VTS 503 TT++ P V +R+ SS SSL+L+WA P P+G +LDYE+KY EK +EG +S + + Sbjct: 428 TTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKT 487 Query: 504 QMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGS 563 N +L GL+ A Y+VQVRAR+ AGYG + + +T + G +EQL LI G+ Sbjct: 488 SENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEG---WREQLALIAGT 544 Query: 564 ATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY-IAPGMKVYIDPFTYEDPNEAVR 622 A G+V V+ V+V+A++CLRKQ +G ++EY++K QY I G KVYIDPFTYEDPNEAVR Sbjct: 545 AVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVR 604 Query: 623 EFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSE 682 EFAKEIDVS VKIEEVIGAGEFGEVCRGRLK PG++E VAIKTLK GYTERQRR+FLSE Sbjct: 605 EFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSE 664 Query: 683 ASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGI 742 ASIMGQF+HPNIIRLEGVVT S PVMILTEFMEN ALDSFLRLNDGQFTVIQLVGMLRGI Sbjct: 665 ASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGI 724 Query: 743 AAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPI 802 A+GM+YL+EM+YVHRDLAARNILVNSNLVCKVSDFGLSRFLE++ SDPTYTSSLGGKIPI Sbjct: 725 ASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPI 784 Query: 803 RWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMD 862 RWTAPEAIA+RKFTSASD WSYGIVMWEVMS+GERPYWDMSNQDVINA+EQDYRLPPP D Sbjct: 785 RWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPD 844 Query: 863 CPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVP 922 CPT+LHQLMLDCW +DRN RP+F Q+V+ LDK+IRN ASLK++A G S PLLD+ P Sbjct: 845 CPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQP 904 Query: 923 DYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSS 982 Y+ F +VG+WL AIKMGRY+ESF +AGF SF+LV+Q++AEDLLRIGVTLAGHQKKIL+S Sbjct: 905 HYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILAS 964 Query: 983 IQDMRLQMNQTLP 995 +Q M+ Q P Sbjct: 965 VQHMKSQAKPGTP 977 >gi|4758280 ephrin receptor EphA4 [Homo sapiens] Length = 986 Score = 1130 bits (2922), Expect = 0.0 Identities = 564/963 (58%), Positives = 699/963 (72%), Gaps = 19/963 (1%) Query: 37 ALEETLMDTKWVTSELAWTSHP-ESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTG 95 A E TL+D++ V EL W + P E GWEEVS DE PIRTYQVCNV E SQNNWLRT Sbjct: 28 ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87 Query: 96 FIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYV 155 +I R QRVY+E+KFT+RDCNS+P + G+CKETFNL+YYE+D+D F EN +V Sbjct: 88 WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDND----KERFIRENQFV 143 Query: 156 KVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKK 211 K+DTIA DESF+++D G ++NT++R GPLSK GFYLAFQD GAC++L+SVR FYKK Sbjct: 144 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 203 Query: 212 CASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTC 271 C T A FP+T+TGA+ +SLV G+C+ N+ E VP K+YC DGEW+VP+G C C Sbjct: 204 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVP-KMYCGADGEWLVPIGNCLC 262 Query: 272 ATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDS 331 GHE + +C+ C G YKA + C CPP+S + A+ CTC F+RAD+D+ Sbjct: 263 NAGHEE--RSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDA 320 Query: 332 ADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSR 391 A CT PS P +ISNVNETS+ LEWS P++ GGR D+ YNV+CKKC GAG S C Sbjct: 321 ASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKC-GAGDPSKCRP 379 Query: 392 CDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQA 451 C V + P+Q GL +V I+ LLAHT YTFE+ AVNGVS +P P + +V +TTNQA Sbjct: 380 CGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQA 439 Query: 452 APSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQ 509 APS + ++ + S+ L+W P+RPNGVIL+YE+KY+EK + S V + + Sbjct: 440 APSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTD 499 Query: 510 LDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLV 569 + GL P YV VRART AGYG +S P E T + L+V + +G V Sbjct: 500 IKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLV--SVSGSV 557 Query: 570 FVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEID 629 +V +++ A V R++ S ++ ++++ G++ Y+DPFTYEDPN+AVREFAKEID Sbjct: 558 VLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEID 617 Query: 630 VSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQF 689 SC+KIE+VIG GEFGEVC GRLK PG+RE+ VAIKTLK GYT++QRRDFLSEASIMGQF Sbjct: 618 ASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQF 677 Query: 690 DHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYL 749 DHPNII LEGVVTK +PVMI+TE+MEN +LD+FLR NDG+FTVIQLVGMLRGI +GMKYL Sbjct: 678 DHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYL 737 Query: 750 SEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEA 809 S+M+YVHRDLAARNILVNSNLVCKVSDFG+SR LEDDP + YT+ GGKIPIRWTAPEA Sbjct: 738 SDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDP-EAAYTTR-GGKIPIRWTAPEA 795 Query: 810 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQ 869 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI A+E+ YRLPPPMDCP ALHQ Sbjct: 796 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQ 855 Query: 870 LMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTT 929 LMLDCW ++R+ RPKF QIVN LDKLIRN SLK + S + LLD + P+++ + Sbjct: 856 LMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVS 915 Query: 930 VGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQ 989 VGDWL AIKM RYK++F +AG+ + + V + EDL RIG+T HQ KILSS+Q MR Q Sbjct: 916 VGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQ 975 Query: 990 MNQ 992 M Q Sbjct: 976 MQQ 978 >gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapiens] Length = 983 Score = 1102 bits (2849), Expect = 0.0 Identities = 549/967 (56%), Positives = 703/967 (72%), Gaps = 21/967 (2%) Query: 39 EETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIW 98 E L+D+K + EL W S+P GWEE+SG DE PIRTYQVCNV + SQNNWLRT ++ Sbjct: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88 Query: 99 RRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVD 158 R Q++YVELKFT+RDCNSIP + G+CKETFNL+Y E+D D + E+ + K+D Sbjct: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144 Query: 159 TIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCAS 214 TIA DESF+++D G ++NT++R GP++K GFYLAFQD GAC++L+SVR ++KKC Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204 Query: 215 TTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATG 274 T A+FP+T+ + SLV G+C+ N+ E P ++YC+ +GEW+VP+G C+C G Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262 Query: 275 HEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADS 334 +E + C+ C PG YKA G C CPP+S T + C C NN++RAD D Sbjct: 263 YEE--RGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320 Query: 335 ACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDD 394 ACT PS PR VISN+NETS+IL+WS P D GGR D+ +N+ICKKC C C Sbjct: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKC--GWNIKQCEPCSP 378 Query: 395 NVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPS 454 NV F+PRQ GLT V ++ LLAHT YTFE+ AVNGVS S P ++AAV+ITTNQAAPS Sbjct: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438 Query: 455 EVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQLDG 512 V T++ +S +S++LSW PE PNG+ILDYE+KY+EK E S + ++ +V + Sbjct: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISS 498 Query: 513 LRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVV 572 L+PD YV Q+RART AGYG SR EFET+ + S + + + + + + +A A ++ V Sbjct: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTV 558 Query: 573 AV-VVIAIVCLRKQRHGSDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAVREFAKEIDV 630 + V+I C K +HG+D + ++ PG++ Y+DP TYEDP +AV EFAKE+D Sbjct: 559 VIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDA 618 Query: 631 SCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFD 690 + + I++V+GAGEFGEVC GRLK P ++E+ VAIKTLKVGYTE+QRRDFL EASIMGQFD Sbjct: 619 TNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFD 678 Query: 691 HPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLS 750 HPNIIRLEGVVTKS+PVMI+TE+MEN +LDSFLR +D QFTVIQLVGMLRGIA+GMKYLS Sbjct: 679 HPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLS 738 Query: 751 EMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAI 810 +M YVHRDLAARNIL+NSNLVCKVSDFGLSR LEDDP + YT+ GGKIPIRWT+PEAI Sbjct: 739 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDP-EAAYTTR-GGKIPIRWTSPEAI 796 Query: 811 AYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQL 870 AYRKFTSASDVWSYGIV+WEVMSYGERPYW+MSNQDVI AV++ YRLPPPMDCP AL+QL Sbjct: 797 AYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQL 856 Query: 871 MLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTV 930 MLDCW +DRN RPKF QIV+ LDKLIRN SLK+I SA + S LLD++ D TTF T Sbjct: 857 MLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTT 916 Query: 931 GDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQ- 989 GDWL+ + KE F ++S D +A+++ +D+ ++GVT+ G QKKI+SSI+ + Q Sbjct: 917 GDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQS 976 Query: 990 MNQTLPV 996 N +PV Sbjct: 977 KNGPVPV 983 >gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens] Length = 1015 Score = 1097 bits (2838), Expect = 0.0 Identities = 550/988 (55%), Positives = 708/988 (71%), Gaps = 25/988 (2%) Query: 14 PGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMN 73 P PL LLL L + E L+D++ V +L W + P++GWEE+ DE Sbjct: 35 PRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYA 94 Query: 74 PIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLF 133 PI TYQVC V E +QNNWL T +I R+++ELKFT+RDCNS+P G+CKETFN++ Sbjct: 95 PIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMY 154 Query: 134 YYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGF 189 Y+E+D EN Y+K+DTIA DESF+ LD G ++NT+VR GPLSK GF Sbjct: 155 YFESDDQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGF 210 Query: 190 YLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVS 249 YLAFQD GAC++L+SVR +YKKC S A+FP+T+TGA+ + L+ G+C+ ++V Sbjct: 211 YLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV-TD 269 Query: 250 VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSR 309 P K++C+ +GEW+VP+G C C G+E K C+ C PG +KA C CPP+S Sbjct: 270 EPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSY 327 Query: 310 TTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRD 369 T A++ C C +++R +SD ACT PS PR ISNVNETS+ LEW P D GGR Sbjct: 328 THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK 387 Query: 370 DLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVN 429 D+ Y + CKKC+ G C C +V ++PRQ GL V + LLAHT YTFE++AVN Sbjct: 388 DVSYYIACKKCNSHAGV--CEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVN 445 Query: 430 GVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMK 489 GVS SP +Y +VN+TTNQAAPS V ++ + +S++LSW P+RPNG+IL+YE+K Sbjct: 446 GVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIK 505 Query: 490 YFEKSEGIASTVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGS 548 YFEK + + T+ S+ ++ +GL+P + YV Q+RART AGYG +SR EFETT + Sbjct: 506 YFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAA 565 Query: 549 GAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYI------A 602 + Q Q+P+I S T G++ ++AVV+ ++ R+ + + E+ + + Sbjct: 566 SSDQ--SQIPVIAVSVTVGVI-LLAVVIGVLLSGRRCGYSKAKQDPEEEKMHFHNGHIKL 622 Query: 603 PGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFV 662 PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE VIGAGEFGEVC GRLK PG+RE+ V Sbjct: 623 PGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPV 682 Query: 663 AIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSF 722 AIKTLKVGYTE+QRRDFL EASIMGQFDHPNII LEGVVTKS+PVMI+TE+MEN +LD+F Sbjct: 683 AIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTF 742 Query: 723 LRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRF 782 L+ NDGQFTVIQLVGMLRGI+AGMKYLS+M YVHRDLAARNIL+NSNLVCKVSDFGLSR Sbjct: 743 LKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRV 802 Query: 783 LEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDM 842 LEDDP + YT+ GGKIPIRWTAPEAIA+RKFTSASDVWSYGIVMWEV+SYGERPYW+M Sbjct: 803 LEDDP-EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEM 860 Query: 843 SNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASL 902 +NQDVI AVE+ YRLP PMDCP AL+QLMLDCW ++RN RPKF +IVN LDKLIRN +SL Sbjct: 861 TNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSL 920 Query: 903 KVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTA 962 K + +A +S L + + + +VG+WL+AIKMGRY E F+ G++S D VAQ+T Sbjct: 921 KTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 980 Query: 963 EDLLRIGVTLAGHQKKILSSIQDMRLQM 990 EDL R+GVTL GHQKKI++S+Q+M++Q+ Sbjct: 981 EDLRRLGVTLVGHQKKIMNSLQEMKVQL 1008 >gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens] Length = 1037 Score = 1088 bits (2813), Expect = 0.0 Identities = 551/1009 (54%), Positives = 705/1009 (69%), Gaps = 45/1009 (4%) Query: 14 PGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMN 73 P PL LLL L + E L+D++ V +L W + P++GWEE+ DE Sbjct: 35 PRRAPLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYA 94 Query: 74 PIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLF 133 PI TYQVC V E +QNNWL T +I R+++ELKFT+RDCNS+P G+CKETFN++ Sbjct: 95 PIHTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMY 154 Query: 134 YYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGF 189 Y+E+D EN Y+K+DTIA DESF+ LD G ++NT+VR GPLSK GF Sbjct: 155 YFESDDQNGRNIK----ENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGF 210 Query: 190 YLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVS 249 YLAFQD GAC++L+SVR +YKKC S A+FP+T+TGA+ + L+ G+C+ ++V Sbjct: 211 YLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSV-TD 269 Query: 250 VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSR 309 P K++C+ +GEW+VP+G C C G+E K C+ C PG +KA C CPP+S Sbjct: 270 EPPKMHCSAEGEWLVPIGKCMCKAGYEE--KNGTCQVCRPGFFKASPHIQSCGKCPPHSY 327 Query: 310 TTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRD 369 T A++ C C +++R +SD ACT PS PR ISNVNETS+ LEW P D GGR Sbjct: 328 THEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRK 387 Query: 370 DLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVN 429 D+ Y + CKKC+ G C C +V ++PRQ GL V + LLAHT YTFE++AVN Sbjct: 388 DVSYYIACKKCNSHAGV--CEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVN 445 Query: 430 GVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMK 489 GVS SP +Y +VN+TTNQAAPS V ++ + +S++LSW P+RPNG+IL+YE+K Sbjct: 446 GVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIK 505 Query: 490 YFEKSEGIASTVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGS 548 YFEK + + T+ S+ ++ +GL+P + YV Q+RART AGYG +SR EFETT + Sbjct: 506 YFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAA 565 Query: 549 GAQQLQEQLPLIVGSATAGLVFVVAVVVIAIV-------CLR------------------ 583 + Q Q+P+I S T G++ + V+ + + C R Sbjct: 566 SSDQ--SQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGY 623 Query: 584 -KQRHGSDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGA 641 K + + E +I PG++ YIDP TYEDPN+AV EFAKEI+ SC+ IE VIGA Sbjct: 624 SKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGA 683 Query: 642 GEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVV 701 GEFGEVC GRLK PG+RE+ VAIKTLKVGYTE+QRRDFL EASIMGQFDHPNII LEGVV Sbjct: 684 GEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVV 743 Query: 702 TKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAA 761 TKS+PVMI+TE+MEN +LD+FL+ NDGQFTVIQLVGMLRGI+AGMKYLS+M YVHRDLAA Sbjct: 744 TKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAA 803 Query: 762 RNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDV 821 RNIL+NSNLVCKVSDFGLSR LEDDP + YT+ GGKIPIRWTAPEAIA+RKFTSASDV Sbjct: 804 RNILINSNLVCKVSDFGLSRVLEDDP-EAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDV 861 Query: 822 WSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNL 881 WSYGIVMWEV+SYGERPYW+M+NQDVI AVE+ YRLP PMDCP AL+QLMLDCW ++RN Sbjct: 862 WSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNS 921 Query: 882 RPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGR 941 RPKF +IVN LDKLIRN +SLK + +A +S L + + + +VG+WL+AIKMGR Sbjct: 922 RPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGR 981 Query: 942 YKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQM 990 Y E F+ G++S D VAQ+T EDL R+GVTL GHQKKI++S+Q+M++Q+ Sbjct: 982 YTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030 >gi|4758282 ephrin receptor EphA7 [Homo sapiens] Length = 998 Score = 1076 bits (2783), Expect = 0.0 Identities = 551/969 (56%), Positives = 688/969 (71%), Gaps = 25/969 (2%) Query: 37 ALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGF 96 A E L+D+K +EL W S P +GWEE+SG DE PIRTYQVC V E +QNNWLRT + Sbjct: 30 AKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNW 89 Query: 97 IWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVK 156 I + + QR++VELKFT+RDCNS+P + G+CKETFNL+YYE D D EN YVK Sbjct: 90 ISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIR----ENLYVK 145 Query: 157 VDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKC 212 +DTIA DESF++ D G ++NT+VR GPLSK GFYLAFQD GAC++L+SV+ +YKKC Sbjct: 146 IDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKC 205 Query: 213 ASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPL-KLYCNGDGEWMVPVGACTC 271 S A+FP+T+TG+E +SLV GTC+ +A E + +++C+ +GEW+VP+G C C Sbjct: 206 WSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCIC 265 Query: 272 ATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDS 331 G++ K C PC G YK+ + C CP +S + +S C C + +YRA SD Sbjct: 266 KAGYQQ--KGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDP 323 Query: 332 ADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSR 391 ACT PS P+ +I N+N+T++ LEWS P D GGR+D+ Y ++CK+C G C Sbjct: 324 PYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGE--CVP 381 Query: 392 CDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQA 451 C N+ ++P+Q GL + V + LLAH YTFEV+AVNGVS S +AAV+ITT QA Sbjct: 382 CGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQA 441 Query: 452 APSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKS--EGIASTVTSQMNSVQ 509 APS+V + S+ LSW PE PNGVI +YE+KY+EK E STV ++ S Sbjct: 442 APSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSAS 501 Query: 510 LDGLRPDARYVVQVRARTVAGYGQYSRPAEF----ETTSERGSGAQQLQEQLPLIVGS-- 563 ++ L+P YV Q+RA T AGYG YS + E T + EQ P+I+ + Sbjct: 502 INNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVV 561 Query: 564 ATAGLVFVVAVVVIAIVCLRKQRHG-SDSEYTEKLQQYIA-PGMKVYIDPFTYEDPNEAV 621 A AG + +V +V I+ R + +D E E+L + PG K YIDP TYEDPN AV Sbjct: 562 AVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAV 621 Query: 622 REFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLS 681 +FAKE+D SC+KIE VIGAGEFGEVC GRLK PG+R+V VAIKTLKVGYTE+QRRDFL Sbjct: 622 HQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLC 681 Query: 682 EASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRG 741 EASIMGQFDHPN++ LEGVVT+ +PVMI+ EFMEN ALD+FLR +DGQFTVIQLVGMLRG Sbjct: 682 EASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRG 741 Query: 742 IAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIP 801 IAAGM+YL++M YVHRDLAARNILVNSNLVCKVSDFGLSR +EDDP + YT++ GGKIP Sbjct: 742 IAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDP-EAVYTTT-GGKIP 799 Query: 802 IRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPM 861 +RWTAPEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI A+E+ YRLP PM Sbjct: 800 VRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPM 859 Query: 862 DCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTV 921 DCP LHQLMLDCW ++R RPKF QIV LDK+IRN SLK S PLLD+ Sbjct: 860 DCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNT 919 Query: 922 PDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILS 981 PD+TTF +VG+WL AIKM RYK++F +AG+ S + VA+MT ED++ +G+TL GHQKKI+S Sbjct: 920 PDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMS 979 Query: 982 SIQDMRLQM 990 SIQ MR QM Sbjct: 980 SIQTMRAQM 988 >gi|145312251 EPH receptor A6 isoform a [Homo sapiens] Length = 1130 Score = 1035 bits (2677), Expect = 0.0 Identities = 541/1024 (52%), Positives = 682/1024 (66%), Gaps = 73/1024 (7%) Query: 26 LPLLLL-PAGCRALEET---LMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVC 81 LPLL P C + L+DT V EL W ++P +GW+ ++ DE PI TYQVC Sbjct: 111 LPLLTAWPGDCSHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVC 170 Query: 82 NVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDV 141 NV E +QNNWLRT +I R Q++YVE+KFT+RDCNSIP + G+CKETFNLFY E+D Sbjct: 171 NVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESH 230 Query: 142 ASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQG 197 P N Y K+DTIA DESF+++D G ++NT++R GP+ + GFYLAFQD G Sbjct: 231 GIKFKP----NQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIG 286 Query: 198 ACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCN 257 AC++L+SVR FYKKC T A+FP+T+ + +SLV G+C+ +A E P KLYC Sbjct: 287 ACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTP-KLYCG 345 Query: 258 GDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASI 317 DG+W+VP+G C C+TG+E E C C PG YKA G C CPP+S T A S+ Sbjct: 346 ADGDWLVPLGRCICSTGYEEI--EGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSV 403 Query: 318 CTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVIC 377 C C ++RA+ D ACT PS PR V+ N+NET+LILEWS P D GGR DL Y+VIC Sbjct: 404 CQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVIC 463 Query: 378 KKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPL 437 KKC S C C + F+PR GL V + ++H YTFE++A+NGVS S Sbjct: 464 KKC--GLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFS 521 Query: 438 PPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEG- 496 P + A+ +TT+Q APS + +R +S +S+ LSW P NG ILDYE+KY+EK Sbjct: 522 PKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQ 581 Query: 497 -IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQE 555 S+ S+ SV + GL+P +YV +R RT GY YS+ EFET E A + Q Sbjct: 582 LTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAE-QG 640 Query: 556 QLPLIVGSATAGLVFVVAVVVIAIVCLRKQRH-GSDSEYTEKLQQYIA------PGMKVY 608 Q+ +I +A G +V + + ++ R Q + + + EK + ++ PG+K Y Sbjct: 641 QILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTY 700 Query: 609 IDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLK 668 IDP TYEDP+ AV EFAKEID S ++IE VIGAGEFGEVC GRLK PG+RE+ VAIKTLK Sbjct: 701 IDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLK 760 Query: 669 VGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTK------------------------- 703 G+ +RQRRDFL EASIMGQFDHPNIIRLEGVVTK Sbjct: 761 GGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQ 820 Query: 704 -----------------SRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746 RPVMI+ E+MEN +LDSFLR +DG FTVIQLVGMLRGIA+GM Sbjct: 821 APHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGM 880 Query: 747 KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806 KYLS+M YVHRDLAARNILVNSNLVCKVSDFGLSR LEDDP + YT++ GGKIPIRWTA Sbjct: 881 KYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EAAYTTT-GGKIPIRWTA 938 Query: 807 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTA 866 PEAIAYRKF+SASD WSYGIVMWEVMSYGERPYW+MSNQDVI ++E+ YRLP PM CP + Sbjct: 939 PEAIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPAS 998 Query: 867 LHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTT 926 LHQLML CW ++RN RPKF+ IV+ LDKLIRN ++L + + + P VP+Y Sbjct: 999 LHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTL--VEDILVMPESPGEVPEYPL 1056 Query: 927 FTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDM 986 F TVGDWLD+IKMG+YK +FV+AGF +FDL+++M+ +D+ RIGV L GHQ++I+SSIQ + Sbjct: 1057 FVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTL 1116 Query: 987 RLQM 990 RL M Sbjct: 1117 RLHM 1120 >gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens] Length = 1005 Score = 991 bits (2562), Expect = 0.0 Identities = 514/1020 (50%), Positives = 688/1020 (67%), Gaps = 60/1020 (5%) Query: 11 SPPPGLLPLLPPLLLLPLLLLPAGCRAL---EETLMDTKWVTSELAWTSHPESGWEEVSG 67 +P G LP P L ++ A C + E L+DT + + W ++P GW+ ++ Sbjct: 2 APARGRLP--PALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINE 59 Query: 68 YDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCK 127 DE+ PI TYQVCNV +QNNWLRT ++ R +RVY E+KFT+RDCNS+P + G+CK Sbjct: 60 VDESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCK 119 Query: 128 ETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGP 183 ETFNL+Y E+D D+ +++ E+ ++K+DTIA DESF+ D G ++NT+VRS GP Sbjct: 120 ETFNLYYLESDRDLGASTQ----ESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGP 175 Query: 184 LSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIP 243 LSK GFYLAFQD GAC++++S+R +YKKC + A F E +TGA+ +SLV G C+ Sbjct: 176 LSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVR 235 Query: 244 NAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLP 303 ++ E P K+YC+ +GEW+VP+G C C+ G+E + C C G YK+ G+ C Sbjct: 236 HSEERDTP-KMYCSAEGEWLVPIGKCVCSAGYEE--RRDACVACELGFYKSAPGDQLCAR 292 Query: 304 CPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPR 363 CPP+S + +PAA C C ++YRA D SACT PS P +IS+VN TS+ LEW+ P Sbjct: 293 CPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPL 352 Query: 364 DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423 D GGR D+ YN +C++C A S C C FVP+Q L + + +++LLAH Y+F Sbjct: 353 DPGGRSDITYNAVCRRCPWA--LSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSF 410 Query: 424 EVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVI 483 ++AVNGVS SP P R A VNITTNQAAPS+V +R + +S++L W PE+PNG+I Sbjct: 411 WIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGII 470 Query: 484 LDYEMKYFEKSEGIAS--TVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFE 541 L+YE+KY+EK + + S T+ + + GL+P RYV QVRART AG G++S+ E E Sbjct: 471 LEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVE 530 Query: 542 TTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRH--------GSDSEY 593 T G + + IV L + +VV+ ++ + K+RH SD E Sbjct: 531 T------GKPRPRYDTRTIVWIC---LTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEK 581 Query: 594 TEK----------LQQYIAPGM----KVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVI 639 L + PG + Y +P TYE+P A R F +EI+ S + IE++I Sbjct: 582 MHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKII 641 Query: 640 GAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEG 699 G+G+ GEVC GRL+ PG+R+V VAIK LK GYTERQRRDFLSEASIMGQFDHPNIIRLEG Sbjct: 642 GSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEG 701 Query: 700 VVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDL 759 VVT+ R MI+TE+MEN +LD+FLR +DGQFT++QLVGMLRG+ AGM+YLS++ YVHRDL Sbjct: 702 VVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDL 761 Query: 760 AARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSAS 819 AARN+LV+SNLVCKVSDFGLSR LEDDP D YT++ GGKIPIRWTAPEAIA+R F+SAS Sbjct: 762 AARNVLVDSNLVCKVSDFGLSRVLEDDP-DAAYTTT-GGKIPIRWTAPEAIAFRTFSSAS 819 Query: 820 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDR 879 DVWS+G+VMWEV++YGERPYW+M+N+DVI++VE+ YRLP PM CP ALHQLMLDCW +DR Sbjct: 820 DVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDR 879 Query: 880 NLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFT------TVGDW 933 RP+FSQIV+ LD LIR+ SL+ A+ S P R+ D + TVGDW Sbjct: 880 AQRPRFSQIVSVLDALIRSPESLRATATV-SRCPPPAFVRSCFDLRGGSGGGGGLTVGDW 938 Query: 934 LDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQT 993 LD+I+MGRY++ F + G++S +V +M A+D+ +G+TL GHQKKIL SIQ MR Q+ T Sbjct: 939 LDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTST 998 >gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] Length = 1021 Score = 885 bits (2286), Expect = 0.0 Identities = 471/1018 (46%), Positives = 637/1018 (62%), Gaps = 65/1018 (6%) Query: 28 LLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRES- 86 +LLL + ALEE L+DT TSE+ W ++P GW+EVS D+ RT++ C+V + Sbjct: 22 VLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGAP 81 Query: 87 ---SQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVAS 143 Q+NWL+T F+ RR QR ++ L F+VR C+S+ G+C+ETF L+Y +A+ + Sbjct: 82 PGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPDSP 141 Query: 144 ASSPFWMENPYVKVDTIAPDESFSRLDAG----------------------RVNTKVRSF 181 S W + KVDTIA DESF + ++N K RSF Sbjct: 142 DSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSF 201 Query: 182 GPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPET-LTGAEPTSLVIAPGT 240 GPL++ GFY+AFQD GAC++L++VR F C + FA FPET +GA SLV A GT Sbjct: 202 GPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGT 261 Query: 241 CIPNAVEVS---------VPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGS 291 C+ +A P +L+CNG+G+WMV VG C C G++PA + C+ CP G Sbjct: 262 CVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGL 321 Query: 292 YKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVN 351 YK+ G PC PCP S +PAA +C C FYRA SD ++ CT PS P+ + V Sbjct: 322 YKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQ 381 Query: 352 ETSLILEWSEPRDLGGRDDLLYNVICKKCHG-----AGGASACSRCDDNVEFVPRQLGLT 406 ++L+L W PR+LGGR DLL+NV+CK+C G +GG C RC D V F PRQ GLT Sbjct: 382 GSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLT 441 Query: 407 ERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSG 466 E RV + L AH Y EVQAVNGVS SP PP+ AA+N++T+ PS VP + S + Sbjct: 442 ESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRAS 501 Query: 467 SSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQLDGLRPDARYVVQVR 524 +S+T+SW P++ NG ILDY+++Y++++E + T+TS+ N+ + L P Y QVR Sbjct: 502 NSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVR 561 Query: 525 ARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVV--AVVVIAIVCL 582 ART AG+G Y F+T + G + QL E+L L++GS L F++ A+ V+A+V Sbjct: 562 ARTAAGHGPYGGKVYFQTLPQ-GELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQ 620 Query: 583 RKQRHGSDSEYTEKLQQYIAPGM--KVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIG 640 RK+R + YTE+LQQY +PG+ K YIDP TYEDP +A+RE A+E+D + +KIEEVIG Sbjct: 621 RKRR---GTGYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIG 677 Query: 641 AGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGV 700 G FGEV +GRL+ GRRE VAI+ L G E + FL A+++GQF HPNI+RLEGV Sbjct: 678 TGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGV 737 Query: 701 VTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLA 760 VTKSRP+M+LTEFME LDSFLR +GQF+ +QLV M RG+AA M+YLS +VHR L+ Sbjct: 738 VTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLS 797 Query: 761 ARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASD 820 A ++LVNS+LVCKV+ G S P P+ +RW APE IA+ K T++SD Sbjct: 798 AHSVLVNSHLVCKVARLGHS------PQGPSCL--------LRWAAPEVIAHGKHTTSSD 843 Query: 821 VWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRN 880 VWS+GI+MWEVMSYGERPYWDMS Q+V+NA+EQ++RLPPP CP LH LMLD W +DR Sbjct: 844 VWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRA 903 Query: 881 LRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMG 940 RP F Q+V DK+IR +L+ SQ LL D+ + WL AI + Sbjct: 904 RRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLE 963 Query: 941 RYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV 998 Y+++F G +F VAQ++ EDL +G+TLAGHQKK+L IQ ++ + Q V+V Sbjct: 964 CYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV 1021 >gi|32967311 ephrin receptor EphA2 [Homo sapiens] Length = 976 Score = 875 bits (2260), Expect = 0.0 Identities = 470/980 (47%), Positives = 626/980 (63%), Gaps = 44/980 (4%) Query: 29 LLLPAGCRALEETLMDTKWVTSELAWTSHPES-GWEEVSGYDEAMNPIRTYQVCNVRESS 87 L A + E L+D EL W +HP GW+ + M PI Y VCNV Sbjct: 18 LAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGD 76 Query: 88 QNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSP 147 Q+NWLRT +++R + +R+++ELKFTVRDCNS P SCKETFNL+Y E+D D + Sbjct: 77 QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTN--- 133 Query: 148 FWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLI 203 + + + K+DTIAPDE D ++N + RS GPL++ GFYLAFQD GAC++L+ Sbjct: 134 -FQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALL 192 Query: 204 SVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPL-----KLYCNG 258 SVR +YKKC G A FPET+ G++ SL GTC+ +AV VP +++C Sbjct: 193 SVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAV---VPPGGEEPRMHCAV 249 Query: 259 DGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASIC 318 DGEW+VP+G C C G+E E C+ C PG +K + E PCL CP ++ + A+ C Sbjct: 250 DGEWLVPIGQCLCQAGYEKV--EDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307 Query: 319 TCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICK 378 C F+RA D A CT PS P + + + L W+ P+D GGR+D++Y+V C+ Sbjct: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367 Query: 379 KCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLP 438 +C G C C+ +V + GLT V +S L H YTF V+A NGVSG Sbjct: 368 QCWPESGE--CGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT-S 424 Query: 439 PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIA 498 + +++ NQ P P +RL S +SL++SW+ P + YE+ Y +K + + Sbjct: 425 RSFRTASVSINQTEP---PKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNS 481 Query: 499 STVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQL 557 V ++ SV LD L PD Y+VQV+A T G G S+ EF+T S GSG Sbjct: 482 YNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLA----- 536 Query: 558 PLIVGSATAGLVFVVAVVVIAIVCLRKQ-----RHGSDSEYTEKLQQYIAPGMKVYIDPF 612 ++G G+V ++ + + R++ R + Y K +Q + P +K Y+DP Sbjct: 537 --VIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQ-LKP-LKTYVDPH 592 Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLK-QPGRREVFVAIKTLKVGY 671 TYEDPN+AV +F EI SCV ++VIGAGEFGEV +G LK G++EV VAIKTLK GY Sbjct: 593 TYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGY 652 Query: 672 TERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFT 731 TE+QR DFL EA IMGQF H NIIRLEGV++K +P+MI+TE+MEN ALD FLR DG+F+ Sbjct: 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFS 712 Query: 732 VIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791 V+QLVGMLRGIAAGMKYL+ MNYVHRDLAARNILVNSNLVCKVSDFGLSR LEDDP + T Sbjct: 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EAT 771 Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851 YT+S GGKIPIRWTAPEAI+YRKFTSASDVWS+GIVMWEVM+YGERPYW++SN +V+ A+ Sbjct: 772 YTTS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAI 830 Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSG 911 +RLP PMDCP+A++QLM+ CW ++R RPKF+ IV+ LDKLIR SLK +A Sbjct: 831 NDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPR 890 Query: 912 MSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVT 971 +S L + + F TV +WL++IKM +Y E F++AG+ + + V QMT +D+ RIGV Sbjct: 891 VSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVR 950 Query: 972 LAGHQKKILSSIQDMRLQMN 991 L GHQK+I S+ ++ Q+N Sbjct: 951 LPGHQKRIAYSLLGLKDQVN 970 >gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] Length = 1008 Score = 803 bits (2073), Expect = 0.0 Identities = 431/1001 (43%), Positives = 616/1001 (61%), Gaps = 27/1001 (2%) Query: 12 PPPGLLPLLPPLLLLPLLLLPAGCRALEET-LMDTKWVTSELAWTSHPESGWEEVSGYDE 70 P P L L L L LLL P EE L+D+K +EL WT+ P +GWEE+SG DE Sbjct: 7 PHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDE 66 Query: 71 AMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETF 130 PIRTYQVCNV E +Q+NWL+TG+I R QR++VEL+FT+RDC+SIP G+CKETF Sbjct: 67 HDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETF 126 Query: 131 NLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSK 186 N++Y E ++D+ P K+DTIA DESF++ D G ++NT+VR GPLS+ Sbjct: 127 NVYYLETEADLGRGRPRLGGSRPR-KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSR 185 Query: 187 AGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAV 246 GF+LAFQD GAC++L+SVR +YK+C +T G A FP T + ++LV GTC+ ++ Sbjct: 186 RGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSE 245 Query: 247 -EVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCP 305 E P +++C DGEW+VPVG C+C+ G + + C CPPG YK C PCP Sbjct: 246 GEPGSPPRMHCGADGEWLVPVGRCSCSAGFQE--RGDFCEACPPGFYKVSPRRPLCSPCP 303 Query: 306 PNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILE--WSEPR 363 +SR A++ C C +++ R+ +D ++CT PS PR + +++ + L+L W P Sbjct: 304 EHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPA 363 Query: 364 DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423 D GGR D+ Y+++C +C G A AC C V F+PRQ GL ER + HL RYT Sbjct: 364 DSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTV 423 Query: 424 EVQAVNGVSGKSPLP-PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPP---ERP 479 V A+NGVSG + YA V ++T AP E +R S++LSW P P Sbjct: 424 RVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAP 483 Query: 480 NGVILDYEMKYFEK--SEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQ---Y 534 +YE++Y+EK SE S V + +V + L+P RYV Q+RA + + + Sbjct: 484 GANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSF 543 Query: 535 SRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAI---VCLRKQRHGSDS 591 + E +T E SG++ + + V + +A LV + V+AI C + G Sbjct: 544 NPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAH 603 Query: 592 EYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGR 651 + E + P + ++DP + D +AV FAKE+D V +E +G G FGE+C G Sbjct: 604 DEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGC 663 Query: 652 LKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILT 711 L+ PGR+E+ VA+ L+ ++ QR FL+EA +GQFDH +I+RLEGVVT+ +MI+T Sbjct: 664 LQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVT 723 Query: 712 EFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLV 771 E+M + ALD FLR ++GQ QL+G+L G+A+ MKYLSEM YVHR LAAR++LV+S+LV Sbjct: 724 EYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLV 783 Query: 772 CKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEV 831 CK+S FG D S+ YT+ + G+ P W APE + + F+SASDVWS+GI+MWEV Sbjct: 784 CKISGFGRG---PRDRSEAVYTT-MSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEV 839 Query: 832 MSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNT 891 M++GERPYWDMS QDVI AVE +RLPPP +CP LH+LMLDCW +D RP+FSQI + Sbjct: 840 MAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSI 899 Query: 892 LDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGF 951 L K++++ K + PL DR + +F +VG WL+A+ + RYK+SF +AG+ Sbjct: 900 LSKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGY 959 Query: 952 ASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQ 992 S + VA+MTA+DL+ +G++LA H++ +LS I ++ ++ Q Sbjct: 960 GSLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQ 1000 >gi|221316650 ephrin receptor EphA1 [Homo sapiens] Length = 976 Score = 745 bits (1924), Expect = 0.0 Identities = 429/987 (43%), Positives = 575/987 (58%), Gaps = 34/987 (3%) Query: 18 PLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWT-SHPESGWEEVSGYDEAMN--P 74 PL L+LL LP G RA E TLMDT EL W P+ GW E + +N P Sbjct: 6 PLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSE---QQQILNGTP 62 Query: 75 IRTYQVCNVR-ESSQNNWLRTGFIWR-RDVQRVYVELKFTVRDCNSIPNIPG--SCKETF 130 + YQ C ++ ++WLR+ +I+R + RV+VEL+FTVRDC S P G CKETF Sbjct: 63 LYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETF 122 Query: 131 NLFYYEADSDVASASSPFWMENP-YVKVDTIAPDESFSRLD----AGRVNTKVRSFGPLS 185 NL Y E+D DV + P + KV T+A D+SF+ D + ++N + S G L+ Sbjct: 123 NLLYMESDQDVG-----IQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLT 177 Query: 186 KAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNA 245 + G YLAF + GAC++L+SVR FY++C T G A FP+TL G P LV GTC+P+A Sbjct: 178 RRGLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPG--PAGLVEVAGTCLPHA 235 Query: 246 VEVSVPL---KLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCL 302 P +++C+ DGEW+VPVG C C G+E C CP GSY+ CL Sbjct: 236 RASPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCL 295 Query: 303 PCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEP 362 CP S S A+ICTC + YRA + ACT PS PR + + + T L L W P Sbjct: 296 TCPQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPP 355 Query: 363 RDLGGRDDLLYNVICKKCHG-AGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRY 421 D GGR D+ Y+V C +C G A C C V F P GLT VH++ L + Y Sbjct: 356 ADTGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANY 415 Query: 422 TFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPE-RPN 480 TF V+A NGVSG +V+I+ A +LRL L L+WA R Sbjct: 416 TFNVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP 475 Query: 481 GVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEF 540 G L YE+ + E V V L L+PD Y+V+VR T G G +S EF Sbjct: 476 GANLTYELHVLNQDEERYQMVLEPR--VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEF 533 Query: 541 ETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY 600 T+ G ++ ++ G ++ ++V ++QR + + + Sbjct: 534 RTSPPVSRGLTG--GEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDRE 591 Query: 601 IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREV 660 +K Y+D YEDP + +F +E+D + + ++ VIG GEFGEV RG L+ P + Sbjct: 592 DKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCK 651 Query: 661 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALD 720 VAIKTLK Q +FL EA+IMGQF HP+I+ LEGVVTK +P+MI+TEFMEN ALD Sbjct: 652 TVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALD 711 Query: 721 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 780 +FLR + Q QLV ML+GIA+GM YLS NYVHRDLAARNILVN NL CKVSDFGL+ Sbjct: 712 AFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLT 771 Query: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYW 840 R L+D D TY + GGKIPIRWTAPEAIA+R FT+ASDVWS+GIVMWEV+S+G++PY Sbjct: 772 RLLDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 828 Query: 841 DMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAA 900 +MSNQ+V+ ++E YRLPPP+DCP L++LM +CW DR RP F ++ L++L+ N Sbjct: 829 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 888 Query: 901 SLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQM 960 SL+ IA+ M+ L + D + TV +WL++I+M RY F SAG + + V ++ Sbjct: 889 SLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLEL 948 Query: 961 TAEDLLRIGVTLAGHQKKILSSIQDMR 987 TAEDL ++G+TL GHQK+IL SIQ + Sbjct: 949 TAEDLTQMGITLPGHQKRILCSIQGFK 975 >gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapiens] Length = 539 Score = 535 bits (1379), Expect = e-152 Identities = 262/513 (51%), Positives = 347/513 (67%), Gaps = 16/513 (3%) Query: 39 EETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIW 98 E L+D+K + EL W S+P GWEE+SG DE PIRTYQVCNV + SQNNWLRT ++ Sbjct: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88 Query: 99 RRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVD 158 R Q++YVELKFT+RDCNSIP + G+CKETFNL+Y E+D D + E+ + K+D Sbjct: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDD----HGVKFREHQFTKID 144 Query: 159 TIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCAS 214 TIA DESF+++D G ++NT++R GP++K GFYLAFQD GAC++L+SVR ++KKC Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204 Query: 215 TTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATG 274 T A+FP+T+ + SLV G+C+ N+ E P ++YC+ +GEW+VP+G C+C G Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262 Query: 275 HEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADS 334 +E + C+ C PG YKA G C CPP+S T + C C NN++RAD D Sbjct: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320 Query: 335 ACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDD 394 ACT PS PR VISN+NETS+IL+WS P D GGR D+ +N+ICKKC C C Sbjct: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKC--GWNIKQCEPCSP 378 Query: 395 NVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPS 454 NV F+PRQ GLT V ++ LLAHT YTFE+ AVNGVS S P ++AAV+ITTNQAAPS Sbjct: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438 Query: 455 EVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQLDG 512 V T++ +S +S++LSW PE PNG+ILDYE+KY+EK E S + ++ +V + Sbjct: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISS 498 Query: 513 LRPDARYVVQVRARTVAGYGQYSRPAEFETTSE 545 L+PD YV Q+RART AGYG SR EFET+ + Sbjct: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531 >gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapiens] Length = 495 Score = 414 bits (1065), Expect = e-115 Identities = 205/448 (45%), Positives = 286/448 (63%), Gaps = 18/448 (4%) Query: 11 SPPPGLLPLLPPLLLLPLLLLPAGCRAL---EETLMDTKWVTSELAWTSHPESGWEEVSG 67 +P G LP P L ++ A C + E L+DT + + W ++P GW+ ++ Sbjct: 2 APARGRLP--PALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINE 59 Query: 68 YDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCK 127 DE+ PI TYQVCNV +QNNWLRT ++ R +RVY E+KFT+RDCNS+P + G+CK Sbjct: 60 VDESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCK 119 Query: 128 ETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGP 183 ETFNL+Y E+D D+ +++ E+ ++K+DTIA DESF+ D G ++NT+VRS GP Sbjct: 120 ETFNLYYLESDRDLGAST----QESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGP 175 Query: 184 LSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIP 243 LSK GFYLAFQD GAC++++S+R +YKKC + A F E +TGA+ +SLV G C+ Sbjct: 176 LSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVR 235 Query: 244 NAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLP 303 ++ E P K+YC+ +GEW+VP+G C C+ G+E + C C G YK+ G+ C Sbjct: 236 HSEERDTP-KMYCSAEGEWLVPIGKCVCSAGYE--ERRDACVACELGFYKSAPGDQLCAR 292 Query: 304 CPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPR 363 CPP+S + +PAA C C ++YRA D SACT PS P +IS+VN TS+ LEW+ P Sbjct: 293 CPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPL 352 Query: 364 DLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTF 423 D GGR D+ YN +C++C A S C C FVP+Q L + + +++LLAH Y+F Sbjct: 353 DPGGRSDITYNAVCRRCPWA--LSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSF 410 Query: 424 EVQAVNGVSGKSPLPPRYAAVNITTNQA 451 ++AVNGVS SP P R A VNITTNQA Sbjct: 411 WIEAVNGVSDLSPEPRRAAVVNITTNQA 438 Score = 31.6 bits (70), Expect = 3.9 Identities = 13/29 (44%), Positives = 17/29 (58%) Query: 453 PSEVPTLRLHSSSGSSLTLSWAPPERPNG 481 P P + S +G+S+TL WAPP P G Sbjct: 328 PPSAPVNLISSVNGTSVTLEWAPPLDPGG 356 >gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] Length = 295 Score = 255 bits (651), Expect = 2e-67 Identities = 132/271 (48%), Positives = 180/271 (66%), Gaps = 7/271 (2%) Query: 12 PPPGLLPLLPPLLLLPLLLLPAGCRALEET-LMDTKWVTSELAWTSHPESGWEEVSGYDE 70 P P L L L L LLL P EE L+D+K +EL WT+ P +GWEE+SG DE Sbjct: 7 PHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDE 66 Query: 71 AMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETF 130 PIRTYQVCNV E +Q+NWL+TG+I R QR++VEL+FT+RDC+SIP G+CKETF Sbjct: 67 HDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETF 126 Query: 131 NLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSK 186 N++Y E ++D+ P K+DTIA DESF++ D G ++NT+VR GPLS+ Sbjct: 127 NVYYLETEADLGRGRPRLGGSRPR-KIDTIAADESFTQGDLGERKMKLNTEVREIGPLSR 185 Query: 187 AGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAV 246 GF+LAFQD GAC++L+SVR +YK+C +T G A FP T + ++LV GTC+ ++ Sbjct: 186 RGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSE 245 Query: 247 -EVSVPLKLYCNGDGEWMVPVGACTCATGHE 276 E P +++C DGEW+VPVG C+C+ G + Sbjct: 246 GEPGSPPRMHCGADGEWLVPVGRCSCSAGFQ 276 >gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] Length = 526 Score = 219 bits (557), Expect = 1e-56 Identities = 118/284 (41%), Positives = 175/284 (61%), Gaps = 12/284 (4%) Query: 611 PFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVG 670 P P + + A EI +K+E+ +GAG+FGEV + + VA+KT+K G Sbjct: 240 PCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTK----VAVKTMKPG 295 Query: 671 YTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQF 730 + FL+EA++M H +++L VVTK P+ I+TEFM +L FL+ ++G Sbjct: 296 SMSVEA--FLAEANVMKTLQHDKLVKLHAVVTKE-PIYIITEFMAKGSLLDFLKSDEGSK 352 Query: 731 TVI-QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSD 789 + +L+ IA GM ++ + NY+HRDL A NILV+++LVCK++DFGL+R +ED+ Sbjct: 353 QPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE-- 410 Query: 790 PTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIN 849 YT+ G K PI+WTAPEAI + FT SDVWS+GI++ E+++YG PY MSN +VI Sbjct: 411 --YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIR 468 Query: 850 AVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893 A+E+ YR+P P +CP L+ +M+ CW RP F I + LD Sbjct: 469 ALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512 >gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] Length = 1074 Score = 218 bits (556), Expect = 2e-56 Identities = 111/270 (41%), Positives = 165/270 (61%), Gaps = 5/270 (1%) Query: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIM 686 EI +++ IG G+FG+V +G P + VAIKT K ++ R FL EA M Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 497 Query: 687 GQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746 QFDHP+I++L GV+T++ PV I+ E L SFL++ + L+ ++ + Sbjct: 498 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 556 Query: 747 KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806 YL +VHRD+AARN+LV+SN K+ DFGLSR++ED TY + GK+PI+W A Sbjct: 557 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS----TYYKASKGKLPIKWMA 612 Query: 807 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTA 866 PE+I +R+FTSASDVW +G+ MWE++ +G +P+ + N DVI +E RLP P +CP Sbjct: 613 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 672 Query: 867 LHQLMLDCWVRDRNLRPKFSQIVNTLDKLI 896 L+ LM CW D + RP+F+++ L ++ Sbjct: 673 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 702 >gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] Length = 1052 Score = 218 bits (556), Expect = 2e-56 Identities = 111/270 (41%), Positives = 165/270 (61%), Gaps = 5/270 (1%) Query: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIM 686 EI +++ IG G+FG+V +G P + VAIKT K ++ R FL EA M Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475 Query: 687 GQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGM 746 QFDHP+I++L GV+T++ PV I+ E L SFL++ + L+ ++ + Sbjct: 476 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534 Query: 747 KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTA 806 YL +VHRD+AARN+LV+SN K+ DFGLSR++ED TY + GK+PI+W A Sbjct: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS----TYYKASKGKLPIKWMA 590 Query: 807 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTA 866 PE+I +R+FTSASDVW +G+ MWE++ +G +P+ + N DVI +E RLP P +CP Sbjct: 591 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 650 Query: 867 LHQLMLDCWVRDRNLRPKFSQIVNTLDKLI 896 L+ LM CW D + RP+F+++ L ++ Sbjct: 651 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680 >gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] Length = 543 Score = 216 bits (551), Expect = 7e-56 Identities = 123/282 (43%), Positives = 171/282 (60%), Gaps = 12/282 (4%) Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672 T + + + + A EI +++E +G G FGEV G + VAIKTLK G Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312 Query: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732 + FL EA IM + H ++ L VV++ P+ I+TEFM +L FL+ DG++ Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSEE-PIYIVTEFMSKGSLLDFLKEGDGKYLK 369 Query: 733 I-QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791 + QLV M IA GM Y+ MNY+HRDL A NILV NLVCK++DFGL+R +ED+ Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---- 425 Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851 YT+ G K PI+WTAPEA Y +FT SDVWS+GI+ E+++ G PY M N++V+ V Sbjct: 426 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQV 485 Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893 E+ YR+P P CP +LH+LM CW +D + RP F I + L+ Sbjct: 486 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527 >gi|4557665 insulin-like growth factor 1 receptor precursor [Homo sapiens] Length = 1367 Score = 215 bits (548), Expect = 1e-55 Identities = 151/505 (29%), Positives = 249/505 (49%), Gaps = 42/505 (8%) Query: 407 ERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVP-TLRLHSSS 465 + R IS+L T Y ++ + N + K T ++P + Sbjct: 785 KERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRP 844 Query: 466 GSSLTLSWAPPERPNGVILDYEMKYFEKSEGIASTVTSQ----MNSVQLDGLRPDARYVV 521 +S+ L W PE PNG+IL YE+KY + E V+ Q +L+ L P Y Sbjct: 845 ENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNP-GNYTA 903 Query: 522 QVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVC 581 +++A +++G G ++ P F ++ G + + LI+ A L+ V +V++ V Sbjct: 904 RIQATSLSGNGSWTDPVFFYVQAKTG-----YENFIHLIIALPVAVLLIVGGLVIMLYVF 958 Query: 582 LRKQ---RHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEV 638 RK+ R G+ Y +Y + VY+ D E RE + + Sbjct: 959 HRKRNNSRLGNGVLYASVNPEYFSAA-DVYVP-----DEWEVAREK--------ITMSRE 1004 Query: 639 IGAGEFGEVCRGRLKQ--PGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIR 696 +G G FG V G K E VAIKT+ + R+R +FL+EAS+M +F+ +++R Sbjct: 1005 LGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVR 1064 Query: 697 LEGVVTKSRPVMILTEFMENCALDSFLRLNDGQF---------TVIQLVGMLRGIAAGMK 747 L GVV++ +P +++ E M L S+LR + ++ +++ M IA GM Sbjct: 1065 LLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMA 1124 Query: 748 YLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAP 807 YL+ +VHRDLAARN +V + K+ DFG++R D Y G +P+RW +P Sbjct: 1125 YLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTR---DIYETDYYRKGGKGLLPVRWMSP 1181 Query: 808 EAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTAL 867 E++ FT+ SDVWS+G+V+WE+ + E+PY +SN+ V+ V + L P +CP L Sbjct: 1182 ESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDML 1241 Query: 868 HQLMLDCWVRDRNLRPKFSQIVNTL 892 +LM CW + +RP F +I++++ Sbjct: 1242 FELMRMCWQYNPKMRPSFLEIISSI 1266 Score = 32.7 bits (73), Expect = 1.7 Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 12/153 (7%) Query: 348 SNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAG-----GASACSRCDDN---VEFV 399 + ++ +I+ W R RD + + V K+ G AC N V+ Sbjct: 498 TTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLP 557 Query: 400 PRQLGLTERRVHISHLLAHTRYTFEVQAVN--GVSGKSPLPPRYAAVNITTNQAAPSEVP 457 P + E + + L T+Y V+AV V + + I TN + PS Sbjct: 558 PNKD--VEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPL 615 Query: 458 TLRLHSSSGSSLTLSWAPPERPNGVILDYEMKY 490 + S+S S L + W PP PNG + Y +++ Sbjct: 616 DVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRW 648 >gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] Length = 537 Score = 214 bits (546), Expect = 2e-55 Identities = 114/268 (42%), Positives = 169/268 (63%), Gaps = 12/268 (4%) Query: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIM 686 EI +++ + +G G+FGEV G + VAIKTLK G + FL EA IM Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318 Query: 687 GQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVI-QLVGMLRGIAAG 745 + H +++L VV++ P+ I+TE+M +L FL+ +G+ + LV M +AAG Sbjct: 319 KKLKHDKLVQLYAVVSEE-PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377 Query: 746 MKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWT 805 M Y+ MNY+HRDL + NILV + L+CK++DFGL+R +ED+ YT+ G K PI+WT Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE----YTARQGAKFPIKWT 433 Query: 806 APEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPT 865 APEA Y +FT SDVWS+GI++ E+++ G PY M+N++V+ VE+ YR+P P DCP Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 493 Query: 866 ALHQLMLDCWVRDRNLRPKFSQIVNTLD 893 +LH+LM+ CW +D RP F + + L+ Sbjct: 494 SLHELMIHCWKKDPEERPTFEYLQSFLE 521 >gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sapiens] Length = 536 Score = 214 bits (544), Expect = 4e-55 Identities = 120/277 (43%), Positives = 169/277 (61%), Gaps = 12/277 (4%) Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672 T + + + + A EI +++E +G G FGEV G R VAIKTLK G Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305 Query: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732 + FL EA +M + H +++L VV++ P+ I+TE+M +L FL+ G++ Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSEE-PIYIVTEYMSKGSLLDFLKGETGKYLR 362 Query: 733 I-QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791 + QLV M IA+GM Y+ MNYVHRDL A NILV NLVCKV+DFGL+R +ED+ Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---- 418 Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851 YT+ G K PI+WTAPEA Y +FT SDVWS+GI++ E+ + G PY M N++V++ V Sbjct: 419 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV 478 Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQI 888 E+ YR+P P +CP +LH LM CW ++ RP F + Sbjct: 479 ERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYL 515 >gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapiens] Length = 536 Score = 214 bits (544), Expect = 4e-55 Identities = 120/277 (43%), Positives = 169/277 (61%), Gaps = 12/277 (4%) Query: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYT 672 T + + + + A EI +++E +G G FGEV G R VAIKTLK G Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305 Query: 673 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTV 732 + FL EA +M + H +++L VV++ P+ I+TE+M +L FL+ G++ Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSEE-PIYIVTEYMSKGSLLDFLKGETGKYLR 362 Query: 733 I-QLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791 + QLV M IA+GM Y+ MNYVHRDL A NILV NLVCKV+DFGL+R +ED+ Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---- 418 Query: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851 YT+ G K PI+WTAPEA Y +FT SDVWS+GI++ E+ + G PY M N++V++ V Sbjct: 419 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV 478 Query: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQI 888 E+ YR+P P +CP +LH LM CW ++ RP F + Sbjct: 479 ERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYL 515 >gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog isoform B [Homo sapiens] Length = 491 Score = 212 bits (540), Expect = 1e-54 Identities = 112/270 (41%), Positives = 166/270 (61%), Gaps = 11/270 (4%) Query: 625 AKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEAS 684 A EI +K+ + +GAG+FGEV G + VA+KTLK G Q FL EA+ Sbjct: 218 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 271 Query: 685 IMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVI-QLVGMLRGIA 743 +M H ++RL VVT+ P+ I+TE+M +L FL+ ++G ++ +L+ IA Sbjct: 272 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 331 Query: 744 AGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIR 803 GM Y+ NY+HRDL A N+LV+ +L+CK++DFGL+R +ED+ YT+ G K PI+ Sbjct: 332 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE----YTAREGAKFPIK 387 Query: 804 WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDC 863 WTAPEAI + FT SDVWS+GI+++E+++YG+ PY +N DV+ A+ Q YR+P +C Sbjct: 388 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 447 Query: 864 PTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893 P L+ +M CW RP F + + LD Sbjct: 448 PDELYDIMKMCWKEKAEERPTFDYLQSVLD 477 >gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog isoform A [Homo sapiens] Length = 512 Score = 212 bits (540), Expect = 1e-54 Identities = 112/270 (41%), Positives = 166/270 (61%), Gaps = 11/270 (4%) Query: 625 AKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEAS 684 A EI +K+ + +GAG+FGEV G + VA+KTLK G Q FL EA+ Sbjct: 239 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 292 Query: 685 IMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVI-QLVGMLRGIA 743 +M H ++RL VVT+ P+ I+TE+M +L FL+ ++G ++ +L+ IA Sbjct: 293 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 352 Query: 744 AGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIR 803 GM Y+ NY+HRDL A N+LV+ +L+CK++DFGL+R +ED+ YT+ G K PI+ Sbjct: 353 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE----YTAREGAKFPIK 408 Query: 804 WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDC 863 WTAPEAI + FT SDVWS+GI+++E+++YG+ PY +N DV+ A+ Q YR+P +C Sbjct: 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 468 Query: 864 PTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893 P L+ +M CW RP F + + LD Sbjct: 469 PDELYDIMKMCWKEKAEERPTFDYLQSVLD 498 >gi|112789548 lymphocyte-specific protein tyrosine kinase precursor [Homo sapiens] Length = 509 Score = 211 bits (538), Expect = 2e-54 Identities = 119/284 (41%), Positives = 172/284 (60%), Gaps = 12/284 (4%) Query: 611 PFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVG 670 P + P + E E+ +K+ E +GAG+FGEV G + VA+K+LK G Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278 Query: 671 YTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDG-Q 729 FL+EA++M Q H ++RL VVT+ P+ I+TE+MEN +L FL+ G + Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQE-PIYIITEYMENGSLVDFLKTPSGIK 335 Query: 730 FTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSD 789 T+ +L+ M IA GM ++ E NY+HRDL A NILV+ L CK++DFGL+R +ED+ Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393 Query: 790 PTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIN 849 YT+ G K PI+WTAPEAI Y FT SDVWS+GI++ E++++G PY M+N +VI Sbjct: 394 --YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451 Query: 850 AVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLD 893 +E+ YR+ P +CP L+QLM CW RP F + + L+ Sbjct: 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,577,735 Number of Sequences: 37866 Number of extensions: 2036204 Number of successful extensions: 18096 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 672 Number of HSP's successfully gapped in prelim test: 414 Number of HSP's that attempted gapping in prelim test: 12818 Number of HSP's gapped (non-prelim): 3691 length of query: 998 length of database: 18,247,518 effective HSP length: 112 effective length of query: 886 effective length of database: 14,006,526 effective search space: 12409782036 effective search space used: 12409782036 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.