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Search of human proteins with 171543850
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|171543850 RUN domain containing 1 [Homo sapiens]
(613 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|171543850 RUN domain containing 1 [Homo sapiens] 1208 0.0
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 72 1e-12
gi|93102364 SWAP-70 protein [Homo sapiens] 44 4e-04
gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens] 43 0.001
gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens] 43 0.001
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 40 0.006
gi|62177129 Nedd4 binding protein 3 [Homo sapiens] 40 0.006
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 40 0.006
gi|221139761 zinc finger protein 853 [Homo sapiens] 40 0.008
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 40 0.008
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 40 0.008
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 40 0.008
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 40 0.008
gi|16262452 cingulin [Homo sapiens] 39 0.011
gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s... 39 0.018
gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo s... 39 0.018
gi|203096856 kinesin family member 7 [Homo sapiens] 39 0.018
gi|40538728 pleckstrin homology domain containing, family M (wit... 38 0.024
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 38 0.024
gi|51317366 myosin XVIIIB [Homo sapiens] 38 0.024
gi|157388975 coiled-coil domain containing 99 [Homo sapiens] 38 0.024
gi|118498356 kinectin 1 isoform a [Homo sapiens] 38 0.031
gi|118498368 kinectin 1 isoform c [Homo sapiens] 38 0.031
gi|33620775 kinectin 1 isoform a [Homo sapiens] 38 0.031
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 38 0.031
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 38 0.031
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 38 0.031
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 37 0.053
gi|91208420 bassoon protein [Homo sapiens] 37 0.053
gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo sap... 37 0.053
>gi|171543850 RUN domain containing 1 [Homo sapiens]
Length = 613
Score = 1208 bits (3125), Expect = 0.0
Identities = 613/613 (100%), Positives = 613/613 (100%)
Query: 1 MAAVEAAAEPVTVVAAVGPKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEA 60
MAAVEAAAEPVTVVAAVGPKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEA
Sbjct: 1 MAAVEAAAEPVTVVAAVGPKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEA 60
Query: 61 TAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQ 120
TAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQ
Sbjct: 61 TAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQ 120
Query: 121 RLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQRE 180
RLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQRE
Sbjct: 121 RLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQRE 180
Query: 181 KQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSL 240
KQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSL
Sbjct: 181 KQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSL 240
Query: 241 STEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTGGGHCE 300
STEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTGGGHCE
Sbjct: 241 STEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTGGGHCE 300
Query: 301 CKAGGKTGNGCSRTGSSRTPPGNSKTKAEDVKKVRETGLHLMRRALAVLQIFAVSQFGCA 360
CKAGGKTGNGCSRTGSSRTPPGNSKTKAEDVKKVRETGLHLMRRALAVLQIFAVSQFGCA
Sbjct: 301 CKAGGKTGNGCSRTGSSRTPPGNSKTKAEDVKKVRETGLHLMRRALAVLQIFAVSQFGCA 360
Query: 361 TGQIPPTLWQRVQADRDYSPLLKRLEVSVDRVKQLALRQQPHDHVITSANLQDLSLGGKD 420
TGQIPPTLWQRVQADRDYSPLLKRLEVSVDRVKQLALRQQPHDHVITSANLQDLSLGGKD
Sbjct: 361 TGQIPPTLWQRVQADRDYSPLLKRLEVSVDRVKQLALRQQPHDHVITSANLQDLSLGGKD 420
Query: 421 ELTMAVRKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYY 480
ELTMAVRKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYY
Sbjct: 421 ELTMAVRKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYY 480
Query: 481 HAKNGRAYVESPARKLSQSFALPVTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKA 540
HAKNGRAYVESPARKLSQSFALPVTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKA
Sbjct: 481 HAKNGRAYVESPARKLSQSFALPVTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKA 540
Query: 541 LVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVD 600
LVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVD
Sbjct: 541 LVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVD 600
Query: 601 LAVRQLKNIKDAF 613
LAVRQLKNIKDAF
Sbjct: 601 LAVRQLKNIKDAF 613
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 72.0 bits (175), Expect = 1e-12
Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 24/194 (12%)
Query: 412 QDLSLGGKDELTMAV----RKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAP 467
++ S+ G D +T V R L A++ L HGL S LL
Sbjct: 542 KEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPS------------LLGG----- 584
Query: 468 EAMHPWELFVKYYHAKNGRAYVESPARK-LSQSFALPVTGGTVVTPKQSLLTAIHMVLTE 526
A HPW + + R + +R L ++F L G V+TP++ L A+ V
Sbjct: 585 -ACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLD-EDGKVLTPEELLYRAVQSVNVT 642
Query: 527 HDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNL 586
HD D +L++L+C+ LNEQ L W+ ++C S +E YQPWS++ G+
Sbjct: 643 HDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCE 702
Query: 587 LSRLSSLKFSLPVD 600
L L FSL D
Sbjct: 703 LRVLCCFAFSLSQD 716
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 43.9 bits (102), Expect = 4e-04
Identities = 55/227 (24%), Positives = 99/227 (43%), Gaps = 46/227 (20%)
Query: 70 GSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDF 129
GSPP P + R+ R E R+ LA + L+ E + + ++LE+
Sbjct: 311 GSPP--PHKEARQRRKELRKKQ---LAEQEELERQMKELQAANESKQQELEAVRKKLEEA 365
Query: 130 AFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQL 189
A R A++E ++ RL Q++ E Q R T+ E++K + Q+
Sbjct: 366 ASR--------------AAEE------EKKRL----QTQVELQARFSTELEREKLIRQQM 401
Query: 190 KTQL----DDLETFAYQ----EGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISS-- 239
+ Q+ +LE + + E Y L +++ ERQ +E ++KL L E+ SS
Sbjct: 402 EEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKR 461
Query: 240 -------LSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEM 279
L ++ Q +A ++ N +KEQ +++ Q+ LE+
Sbjct: 462 AELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQLEL 508
>gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]
Length = 1516
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 7/111 (6%)
Query: 504 VTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGS 563
V T + P +L ++ +++ P S A + LN + L W N +
Sbjct: 1072 VEASTQLGPSTKVLHGLYNKVSQF-PELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHED 1130
Query: 564 LIEPHYQPWSYM--AHTG----FESALNLLSRLSSLKFSLPVDLAVRQLKN 608
+I+ HYQPW ++ AHT FE L LL L+ L FSL + R L++
Sbjct: 1131 IIQTHYQPWGFLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQS 1181
>gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
Length = 1516
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 7/111 (6%)
Query: 504 VTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGS 563
V T + P +L ++ +++ P S A + LN + L W N +
Sbjct: 1072 VEASTQLGPSTKVLHGLYNKVSQF-PELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHED 1130
Query: 564 LIEPHYQPWSYM--AHTG----FESALNLLSRLSSLKFSLPVDLAVRQLKN 608
+I+ HYQPW ++ AHT FE L LL L+ L FSL + R L++
Sbjct: 1131 IIQTHYQPWGFLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQS 1181
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 40.0 bits (92), Expect = 0.006
Identities = 45/206 (21%), Positives = 90/206 (43%), Gaps = 10/206 (4%)
Query: 87 RRRLDSALLALSSHFAQVQFRLRQ---VVRGAPAEQQRLLRELEDFAFRGCPHVLGY--- 140
R+ L+ +LAL S A + ++ + +++LL++ E + R L Y
Sbjct: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKL 1418
Query: 141 EGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFA 200
E + E D L D R + ++KQ++ + ++K + + + D E A
Sbjct: 1419 EKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEA 1478
Query: 201 YQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPA 260
+E +L + LE + + E ++ + L D+ L + + V V ++
Sbjct: 1479 -REKETKALSLARALE-EALEAKEEFERQNKQLRADMEDLMSS--KDDVGKNVHELEKSK 1534
Query: 261 RVKEQLVEQLKTQIRDLEMFINFIQD 286
R EQ VE+++TQ+ +LE + +D
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATED 1560
Score = 32.0 bits (71), Expect = 1.7
Identities = 42/202 (20%), Positives = 82/202 (40%), Gaps = 20/202 (9%)
Query: 78 RTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHV 137
+T + L +R+LD L A++Q ++ ++ +++ EL+ RG
Sbjct: 1048 KTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE----ELQGALARGDDET 1103
Query: 138 LGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDD-L 196
L + L L+ + +SE+ + + E Q+ E + LKT+L+D L
Sbjct: 1104 LHKNNALKVVRE----LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
Query: 197 ETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQI 256
+T A Q+ Q V EL K L+ + + +++RQR A+ ++
Sbjct: 1160 DTTAAQQELRTKREQEVA---------ELKKALEEETKNHEAQI--QDMRQRHATALEEL 1208
Query: 257 VNPARVKEQLVEQLKTQIRDLE 278
++ L+ + LE
Sbjct: 1209 SEQLEQAKRFKANLEKNKQGLE 1230
>gi|62177129 Nedd4 binding protein 3 [Homo sapiens]
Length = 544
Score = 40.0 bits (92), Expect = 0.006
Identities = 55/180 (30%), Positives = 77/180 (42%), Gaps = 24/180 (13%)
Query: 19 PKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEATAEEPGAAPGSPPDSPGR 78
P+A E + P E RW AE L EA AE A + S
Sbjct: 347 PRAPGTLPEADPSARPEEEARWEVCQKTAEISL-LKQQLREAQAEL--AQKLAEIFSLKT 403
Query: 79 TLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRG----APAEQQRLLRELEDFAFRGC 134
LR RA+ + D+ L+ RLR+ VR AP E+ E +D RG
Sbjct: 404 QLRGSRAQAQAQDAELV-----------RLREAVRSLQEQAPREEAPGSCETDDCKSRG- 451
Query: 135 PHVLGYEGPGDPASDEGDGLPGD--RPRLRGEDQSEQEKQERLETQREKQKELILQLKTQ 192
+LG G G A D + L + + RLRG++Q+ + +QER Q EK++ L Q + Q
Sbjct: 452 --LLGEAG-GSEARDSAEQLRAELLQERLRGQEQALRFEQERRTWQEEKERVLRYQREIQ 508
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 40.0 bits (92), Expect = 0.006
Identities = 50/182 (27%), Positives = 69/182 (37%), Gaps = 37/182 (20%)
Query: 15 AAVGPKAKDE-------EEEEEEPLPPCEAVRWAPVGAVA--EARPGATAFLEEATAEEP 65
+A GP+ K + E+E P P + +P A E P T P
Sbjct: 519 SAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPP 578
Query: 66 GAAPGSPPDSP--GRTLR----RLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQ 119
AP P P G T R RL AE+RR A + Q R Q R +
Sbjct: 579 APAPPVTPSKPMAGTTDREEATRLLAEKRRQ-----AREQREREEQERRLQAERDKRMRE 633
Query: 120 QRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQR 179
++L RE E A R E + + R + Q+EQE+QERL+ Q+
Sbjct: 634 EQLAREAEARAER-----------------EAEARRREEQEAREKAQAEQEEQERLQKQK 676
Query: 180 EK 181
E+
Sbjct: 677 EE 678
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 39.7 bits (91), Expect = 0.008
Identities = 53/261 (20%), Positives = 105/261 (40%), Gaps = 36/261 (13%)
Query: 18 GPKAKDEEEEEEEPLPPCEAVRWAPVGA---VAEARPGATAFLEEATAEEPGAAPGSPPD 74
G ++++EEE +E P APVGA E RPG + ++P P
Sbjct: 48 GSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQP-----EPQQ 102
Query: 75 SPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGC 134
P +L+ + L+ L Q Q Q + Q L EL+
Sbjct: 103 QPQH--EQLQQPQPHLE--LQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQ------- 151
Query: 135 PHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLD 194
+ L +P+ E Q Q++QE+L+TQ+ ++++++ Q +
Sbjct: 152 ------------LMHQQQQL---QPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ 196
Query: 195 DLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVA 254
++ + + L Q +L++Q + + ++ L + L ++ Q +
Sbjct: 197 QVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQ 256
Query: 255 QIVNPARVKEQLVEQLKTQIR 275
Q A++++QL+EQ + Q++
Sbjct: 257 Q--QQAQLQQQLLEQQQAQLQ 275
Score = 30.4 bits (67), Expect = 5.0
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 4/117 (3%)
Query: 83 LRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEG 142
L+ ++ +L LL Q Q L+Q + +QQ+LL++ ++ + E
Sbjct: 255 LQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLE- 313
Query: 143 PGDPASDEGDGLPGDRPRLRGEDQSEQE--KQERLETQREKQKELILQLKTQLDDLE 197
P + E + +P D + +Q QE +Q+ LE Q+E Q++L L+L+ +L LE
Sbjct: 314 PEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQE-QRQLQLKLQEELQQLE 369
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 39.7 bits (91), Expect = 0.008
Identities = 54/259 (20%), Positives = 108/259 (41%), Gaps = 31/259 (11%)
Query: 51 PGATAFLEEATAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQ 110
P A + PGA P P SP + LRA+ R L+ L L A+ + +L++
Sbjct: 56 PLAAPIIPTPVLTSPGAVPPLP--SPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKE 113
Query: 111 VVR-------------GAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGD 157
+ + +Q L R L++ + E + +D D +
Sbjct: 114 LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAI--- 170
Query: 158 RPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVL-- 215
+ + +E+ E L+ + E KE + +L T L+ L+ ++GS D S L
Sbjct: 171 -EMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-DGAASSYQLKQ 228
Query: 216 --ERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQ 273
E+ + D L++ D++ +E + ++L ++ + + V Q E+L+ +
Sbjct: 229 LEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL-------EVVRQQRERLQEE 281
Query: 274 IRDLEMFINFIQDEVGSPL 292
+ E I+ ++++V + L
Sbjct: 282 LSQAESTIDELKEQVDAAL 300
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 39.7 bits (91), Expect = 0.008
Identities = 54/259 (20%), Positives = 108/259 (41%), Gaps = 31/259 (11%)
Query: 51 PGATAFLEEATAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQ 110
P A + PGA P P SP + LRA+ R L+ L L A+ + +L++
Sbjct: 170 PLAAPIIPTPVLTSPGAVPPLP--SPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKE 227
Query: 111 VVR-------------GAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGD 157
+ + +Q L R L++ + E + +D D +
Sbjct: 228 LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAI--- 284
Query: 158 RPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVL-- 215
+ + +E+ E L+ + E KE + +L T L+ L+ ++GS D S L
Sbjct: 285 -EMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-DGAASSYQLKQ 342
Query: 216 --ERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQ 273
E+ + D L++ D++ +E + ++L ++ + + V Q E+L+ +
Sbjct: 343 LEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL-------EVVRQQRERLQEE 395
Query: 274 IRDLEMFINFIQDEVGSPL 292
+ E I+ ++++V + L
Sbjct: 396 LSQAESTIDELKEQVDAAL 414
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 39.7 bits (91), Expect = 0.008
Identities = 54/259 (20%), Positives = 108/259 (41%), Gaps = 31/259 (11%)
Query: 51 PGATAFLEEATAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQ 110
P A + PGA P P SP + LRA+ R L+ L L A+ + +L++
Sbjct: 56 PLAAPIIPTPVLTSPGAVPPLP--SPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKE 113
Query: 111 VVR-------------GAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGD 157
+ + +Q L R L++ + E + +D D +
Sbjct: 114 LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAI--- 170
Query: 158 RPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVL-- 215
+ + +E+ E L+ + E KE + +L T L+ L+ ++GS D S L
Sbjct: 171 -EMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-DGAASSYQLKQ 228
Query: 216 --ERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQ 273
E+ + D L++ D++ +E + ++L ++ + + V Q E+L+ +
Sbjct: 229 LEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL-------EVVRQQRERLQEE 281
Query: 274 IRDLEMFINFIQDEVGSPL 292
+ E I+ ++++V + L
Sbjct: 282 LSQAESTIDELKEQVDAAL 300
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 39.7 bits (91), Expect = 0.008
Identities = 54/259 (20%), Positives = 108/259 (41%), Gaps = 31/259 (11%)
Query: 51 PGATAFLEEATAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQ 110
P A + PGA P P SP + LRA+ R L+ L L A+ + +L++
Sbjct: 190 PLAAPIIPTPVLTSPGAVPPLP--SPSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKE 247
Query: 111 VVR-------------GAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGD 157
+ + +Q L R L++ + E + +D D +
Sbjct: 248 LEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAI--- 304
Query: 158 RPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVL-- 215
+ + +E+ E L+ + E KE + +L T L+ L+ ++GS D S L
Sbjct: 305 -EMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS-DGAASSYQLKQ 362
Query: 216 --ERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQ 273
E+ + D L++ D++ +E + ++L ++ + + V Q E+L+ +
Sbjct: 363 LEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQEL-------EVVRQQRERLQEE 415
Query: 274 IRDLEMFINFIQDEVGSPL 292
+ E I+ ++++V + L
Sbjct: 416 LSQAESTIDELKEQVDAAL 434
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 39.3 bits (90), Expect = 0.011
Identities = 56/213 (26%), Positives = 89/213 (41%), Gaps = 35/213 (16%)
Query: 80 LRRLRAERRRLDSALLA-------LSSHFAQVQFRLRQVVRGAPA---EQQRLLRELEDF 129
L+RL AE+++L+ AL A L++ ++ RL + RG EQQ L R LE+
Sbjct: 767 LQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEE- 825
Query: 130 AFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQL 189
EG G ++ RL D++ + LE E K+ + QL
Sbjct: 826 -----------EGKQREVLRRGKAELEEQKRLL--DRTVDRLNKELEKIGEDSKQALQQL 872
Query: 190 KTQLDDLETFAYQE----------GSYDSLPQSVVLERQRVIIDELIKKLDMNLNE-DIS 238
+ QL+D + A +E + ++ S L R + I L + L + E D +
Sbjct: 873 QAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTA 932
Query: 239 SLSTEELRQRVDAAVAQIVNPARVKEQLVEQLK 271
L E L QR+ + N R ++ QLK
Sbjct: 933 RLDKELLAQRLQGLEQEAENKKRSQDDRARQLK 965
Score = 36.6 bits (83), Expect = 0.070
Identities = 55/200 (27%), Positives = 88/200 (44%), Gaps = 31/200 (15%)
Query: 107 RLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQ 166
RLRQ ++ + AE+ + E A R + G E + D DR R + +
Sbjct: 917 RLRQALQASQAERDTARLDKELLAQR----LQGLEQEAENKKRSQD----DRAR---QLK 965
Query: 167 SEQEKQERLETQREKQKELILQL-------KTQLDDLETFAYQEGS--YDSLPQSVVLER 217
+EK RLET+ +++K + L + Q+D L T QE S D + LER
Sbjct: 966 GLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLER 1025
Query: 218 Q------RVIIDELIKKLDMNLN--EDISSLSTEELR-QRVDAAVAQIVNPARVKEQLVE 268
Q R+ E +K +L+ E + L E L+ + + V Q N R E+ V+
Sbjct: 1026 QNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTN--RKLERKVK 1083
Query: 269 QLKTQIRDLEMFINFIQDEV 288
+L QI D +N +D++
Sbjct: 1084 ELSIQIEDERQHVNDQKDQL 1103
>gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo
sapiens]
Length = 652
Score = 38.5 bits (88), Expect = 0.018
Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 110 QVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLP----GDRPRLR--- 162
+V+R +PA+ R + EL+ +G P++ G E P D A++ P GD R R
Sbjct: 357 KVIR-SPADLIRFIEELKGGTKKGKPNI-GQEQPVDDAAEVPQREPEKERGDPERQREME 414
Query: 163 -----GEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLER 217
ED+ E E + +L + EK+ E IL L + D L + +E D L + +R
Sbjct: 415 EEEDEDEDEDEDEDERQLLGEFEKELEGIL-LPSDRDRLRSETEKELDPDGLKKESERDR 473
Query: 218 QRVIIDELIKKLDMNLNE 235
+ + + KL L E
Sbjct: 474 AMLALTSTLNKLIKRLEE 491
>gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo
sapiens]
Length = 597
Score = 38.5 bits (88), Expect = 0.018
Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 110 QVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLP----GDRPRLR--- 162
+V+R +PA+ R + EL+ +G P++ G E P D A++ P GD R R
Sbjct: 357 KVIR-SPADLIRFIEELKGGTKKGKPNI-GQEQPVDDAAEVPQREPEKERGDPERQREME 414
Query: 163 -----GEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLER 217
ED+ E E + +L + EK+ E IL L + D L + +E D L + +R
Sbjct: 415 EEEDEDEDEDEDEDERQLLGEFEKELEGIL-LPSDRDRLRSETEKELDPDGLKKESERDR 473
Query: 218 QRVIIDELIKKLDMNLNE 235
+ + + KL L E
Sbjct: 474 AMLALTSTLNKLIKRLEE 491
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 38.5 bits (88), Expect = 0.018
Identities = 81/322 (25%), Positives = 132/322 (40%), Gaps = 52/322 (16%)
Query: 5 EAAAEPVTVVAAVGP---KAKDEEEEEEEP-----------LPPCEAVRWAPVGAVAEAR 50
EA AE +T V +G A +EEEEEEEP + C A G++ E R
Sbjct: 603 EAGAELLTEVNRLGSGSSAASEEEEEEEEPPRRTLHLRRNRISNCSQRAGARPGSLPE-R 661
Query: 51 PGATAFLEEATAEEPG--AAPGSPPDSPGRTLRRLRAERRRLDSA---LLALSSHFAQVQ 105
G LEE A PG A GS R + A RL A + L+ + +
Sbjct: 662 KGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRLAQAQQKIRELAINIRMKE 721
Query: 106 FRLRQVVRGAPAEQ------QRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGL--PGD 157
+ ++VR A Q + +RELE A + + EG EG L G+
Sbjct: 722 ELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAEL--SEGQRQLRELEGKELQDAGE 779
Query: 158 RPRLRGEDQSEQEKQERLETQREKQK------ELILQLKTQLDDLE----TFAYQEGSY- 206
R RL+ + Q +++ +EK++ L Q + +L +LE Q+G
Sbjct: 780 RSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQ 839
Query: 207 ----DSLPQSVVLERQRVIIDELIKKLDM--NLNEDISSLSTEEL----RQRVDAAVAQI 256
+ Q LE + +K+L++ + I + TEE+ R+R + +
Sbjct: 840 RRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSV 899
Query: 257 VNPARVKEQLVEQLKTQIRDLE 278
V+ ++++ EQ K +++E
Sbjct: 900 VS-LEQQQKIEEQKKWLDQEME 920
Score = 31.2 bits (69), Expect = 2.9
Identities = 66/283 (23%), Positives = 109/283 (38%), Gaps = 49/283 (17%)
Query: 52 GATAFLEEATAEEPGA--APGSPPDSPGRTLRRLRAERRRLDSA----LLALSSHFAQ-- 103
G + +E A+ E+ A A G D + L L+ + RL+ L AL Q
Sbjct: 459 GPDSGIESASVEDQAAQGAGGRKEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYK 518
Query: 104 -------------VQFRLR-QVVR---GAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDP 146
V+ RLR ++VR G P RLL L +F PH G
Sbjct: 519 LQSDRLREQQEEMVELRLRLELVRPGWGGP----RLLNGLPPGSFVPRPHTAPLGGAH-- 572
Query: 147 ASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSY 206
A G P P G++ +++ E++ RE EL+ ++ +L + A +E
Sbjct: 573 AHVLGMVPPACLP---GDEVGSEQRGEQVTNGREAGAELLTEVN-RLGSGSSAASEEEEE 628
Query: 207 DSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAV------------- 253
+ P L +R I ++ E + +DAA+
Sbjct: 629 EEEPPRRTLHLRRNRISNCSQRAGARPGSLPERKGPELCLEELDAAIPGSRAVGGSKARV 688
Query: 254 -AQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTG 295
A+ V PA E + Q + +IR+L + I ++ +G ++TG
Sbjct: 689 QARQVPPATASEWRLAQAQQKIRELAINIRMKEELIGELVRTG 731
>gi|40538728 pleckstrin homology domain containing, family M (with
RUN domain) member 1 [Homo sapiens]
Length = 1056
Score = 38.1 bits (87), Expect = 0.024
Identities = 35/132 (26%), Positives = 61/132 (46%), Gaps = 7/132 (5%)
Query: 475 LFVKYYHAKNGRAYVESPARKLSQSFALPVTGGTVVTPKQSLLTAIHMVLT-EHDPFKRS 533
+F+ HAK+ RA +K + LP V P +T H++ EH F +
Sbjct: 57 VFIHGLHAKHIRAEAGGKRKKSAHQKPLPQP---VFWPLLKAVTHKHIISELEHLTFVNT 113
Query: 534 ADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYM--AHTGFESALNLLSRLS 591
+A + +ALN+ + ++ L+ + + + +YQP + + A G E L+ L L+
Sbjct: 114 DVGRCRAWLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEEG-EFLLSFLQGLT 172
Query: 592 SLKFSLPVDLAV 603
SL F L A+
Sbjct: 173 SLSFELSYKSAI 184
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 38.1 bits (87), Expect = 0.024
Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 10/112 (8%)
Query: 135 PHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLD 194
P G P PAS++ +PG R E + E+++ + E + EK+K LI++ K +
Sbjct: 6 PAAEGEGTPTQPASEKEPEMPGPRE----ESEEEEDEDDEEEEEEEKEKSLIVEGKREKK 61
Query: 195 DLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELR 246
+E Q S P ++ + + + + I+++ L S T+ELR
Sbjct: 62 KVERLTMQVSSLQREPFTIAQGKGQKLCE--IERIHFFL----SKKKTDELR 107
>gi|51317366 myosin XVIIIB [Homo sapiens]
Length = 2567
Score = 38.1 bits (87), Expect = 0.024
Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 37/235 (15%)
Query: 78 RTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRL-LRELEDFAFRGCPH 136
+ L RAER + + L S QVQ +L V + QQ++ L +LE G
Sbjct: 1458 QVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADE 1517
Query: 137 VLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKEL---ILQLKTQL 193
++ D A E + L R RL Q+ +ERL+++ +KEL + +L++
Sbjct: 1518 ---WQMRFDCAQMENEFL---RKRL-------QQCEERLDSELTARKELEQKLGELQSAY 1564
Query: 194 DDLETFAYQ------EGSYDSLPQSVVLERQRVIIDEL---IKKLDMNLNEDI-SSLSTE 243
D + A+Q + D V+LE Q+ EL KK D+ L + + S+ +
Sbjct: 1565 DGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEK 1624
Query: 244 ELRQRVDA-------AVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSP 291
LR++V + Q+ + KEQ QLK Q+ EM + ++ +GSP
Sbjct: 1625 GLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQV---EMLQDHKRELLGSP 1676
>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
Length = 605
Score = 38.1 bits (87), Expect = 0.024
Identities = 33/88 (37%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 166 QSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLP--QSVVLERQRVIID 223
Q+E E+QERL E++ I L ++ +LE F S +S P S LE D
Sbjct: 310 QTEFEQQERLLAMLEQKNGEIKHLLGEIRNLEKFKNLYDSMESKPSVDSGTLEDNTYYTD 369
Query: 224 ELIKKLDMNLNEDISSLSTEELRQRVDA 251
L KLD NLN++I S E QR+ A
Sbjct: 370 LLQMKLD-NLNKEIESTKGELSIQRMKA 396
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.7 bits (86), Expect = 0.031
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 9/126 (7%)
Query: 169 QEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSV-VLERQRVIIDELIK 227
QEK E+L+T E + ++Q+ T+ ++L + S Q + + +V L++
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797
Query: 228 KLDMNLNE-DISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQD 286
+L ++E D S EEL ++A + ++ N KE+ V+ LK +I+ L+ I +Q
Sbjct: 798 ELKKVIHEKDGKIKSVEEL---LEAELLKVAN----KEKTVQDLKQEIKALKEEIGNVQL 850
Query: 287 EVGSPL 292
E L
Sbjct: 851 EKAQQL 856
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 37.7 bits (86), Expect = 0.031
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 9/126 (7%)
Query: 169 QEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSV-VLERQRVIIDELIK 227
QEK E+L+T E + ++Q+ T+ ++L + S Q + + +V L++
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797
Query: 228 KLDMNLNE-DISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQD 286
+L ++E D S EEL ++A + ++ N KE+ V+ LK +I+ L+ I +Q
Sbjct: 798 ELKKVIHEKDGKIKSVEEL---LEAELLKVAN----KEKTVQDLKQEIKALKEEIGNVQL 850
Query: 287 EVGSPL 292
E L
Sbjct: 851 EKAQQL 856
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.7 bits (86), Expect = 0.031
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 9/126 (7%)
Query: 169 QEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSV-VLERQRVIIDELIK 227
QEK E+L+T E + ++Q+ T+ ++L + S Q + + +V L++
Sbjct: 738 QEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797
Query: 228 KLDMNLNE-DISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQD 286
+L ++E D S EEL ++A + ++ N KE+ V+ LK +I+ L+ I +Q
Sbjct: 798 ELKKVIHEKDGKIKSVEEL---LEAELLKVAN----KEKTVQDLKQEIKALKEEIGNVQL 850
Query: 287 EVGSPL 292
E L
Sbjct: 851 EKAQQL 856
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 37.7 bits (86), Expect = 0.031
Identities = 62/295 (21%), Positives = 110/295 (37%), Gaps = 66/295 (22%)
Query: 5 EAAAEPVTVVAAVGPKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEATAEE 64
EAA E A +E+EEEEE + A G + E++P +F+
Sbjct: 26 EAAEEDAEAEAETEETRAEEDEEEEE-------AKEAEDGPMEESKPKPRSFM------- 71
Query: 65 PGAAPGSPPDSPGRTLRRLRAER--RRLDSALLALSSHFAQVQFRLRQVV---------R 113
P P PD + +R + L+ + +HF + ++V R
Sbjct: 72 PNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 131
Query: 114 GAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQE 173
AEQQR+ E E + + L +R R + E+E +
Sbjct: 132 AERAEQQRIRNERE--------------------KERQNRLAEERAR-----REEEENRR 166
Query: 174 RLETQREKQKEL--ILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDM 231
+ E + K+K L ++ + E + + + + ++ ER++V+ +
Sbjct: 167 KAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAID------- 219
Query: 232 NLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQD 286
+LNED +LR++ I N K L E+ K Q ++ + N I D
Sbjct: 220 HLNED-------QLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRIND 267
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 37.7 bits (86), Expect = 0.031
Identities = 62/295 (21%), Positives = 110/295 (37%), Gaps = 66/295 (22%)
Query: 5 EAAAEPVTVVAAVGPKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEATAEE 64
EAA E A +E+EEEEE + A G + E++P +F+
Sbjct: 36 EAAEEDAEAEAETEETRAEEDEEEEE-------AKEAEDGPMEESKPKPRSFM------- 81
Query: 65 PGAAPGSPPDSPGRTLRRLRAER--RRLDSALLALSSHFAQVQFRLRQVV---------R 113
P P PD + +R + L+ + +HF + ++V R
Sbjct: 82 PNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 141
Query: 114 GAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQE 173
AEQQR+ E E + + L +R R + E+E +
Sbjct: 142 AERAEQQRIRNERE--------------------KERQNRLAEERAR-----REEEENRR 176
Query: 174 RLETQREKQKEL--ILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDM 231
+ E + K+K L ++ + E + + + + ++ ER++V+ +
Sbjct: 177 KAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAID------- 229
Query: 232 NLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQD 286
+LNED +LR++ I N K L E+ K Q ++ + N I D
Sbjct: 230 HLNED-------QLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRIND 277
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 37.7 bits (86), Expect = 0.031
Identities = 52/201 (25%), Positives = 75/201 (37%), Gaps = 24/201 (11%)
Query: 25 EEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEATAEEPGAAPGSPPDSPGRTLRRLR 84
EEE E PP EA R A ++ + E PG + R
Sbjct: 271 EEEGEGQEPPLEAER-------------APREEQQRSLEAPGWEDAERREREERERLEAE 317
Query: 85 AERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLREL---EDFAFRGCPHVLGYE 141
ERRRL + A + RL + R E+ R EL E+ G + E
Sbjct: 318 EERRRLQAQAQAEERRRLEEDARLEER-RRQEEEEGRCAEELKRQEEEEAEGWEELEQQE 376
Query: 142 ----GPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLE 197
GP + + G+G G GE+ E+E Q LE R + EL+ + +L+D E
Sbjct: 377 AEVQGPPEALEETGEGRRGAEEEDLGEE--EEEGQAHLEDWRGQLSELLNDFEERLEDQE 434
Query: 198 TFAYQEGSYDSLPQSVVLERQ 218
EG + + + E Q
Sbjct: 435 RLK-PEGQREHSEEPGICEEQ 454
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 37.0 bits (84), Expect = 0.053
Identities = 53/230 (23%), Positives = 106/230 (46%), Gaps = 14/230 (6%)
Query: 57 LEEATAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAP 116
L+ TAE AP PP P + + +L+ E L L ++ Q + Q++
Sbjct: 140 LKNQTAEP--LAP-EPPAGPSK-VEQLQDETNHLRKELESVGRQL-QAEVENNQMLSLLN 194
Query: 117 AEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLE 176
Q+ LRE E+ + E + ++ + L RLR +++ +E++ERL
Sbjct: 195 RRQEERLREQEERLHEQEERLHEQE---ERLCEQEERLCEQEERLREQEERLREQEERLH 251
Query: 177 TQREK---QKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNL 233
Q E+ Q+E + + + +L + E QE + + + + ER++ + L+++ + L
Sbjct: 252 EQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLER-ERLL 310
Query: 234 NEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLK--TQIRDLEMFI 281
+E L E LRQ+ + Q + + +E+L+ ++R+LE +
Sbjct: 311 DEVEELLEQERLRQQDERLWQQETLRELERLRELERLRELERLRELERML 360
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 37.0 bits (84), Expect = 0.053
Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 22/153 (14%)
Query: 139 GYEGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLET 198
G + P D A G G RP E+ S++E+Q KQ+E +LQL+ + +LE
Sbjct: 2333 GQKPPADAAPGGGSGALS-RPGFEKEEASQEERQ-------RKQQEQLLQLERERVELEK 2384
Query: 199 FAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLST---EELRQRVDAAVAQ 255
L LER+RV + ++ + + ++ L T L+Q+ + AQ
Sbjct: 2385 LR-------QLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQ 2437
Query: 256 IVNPARVKEQLVEQLKTQIRDLEMFINFIQDEV 288
A +EQL +Q + Q+ ++ +Q ++
Sbjct: 2438 F---ALQREQLAQQ-RLQLEQIQQLQQQLQQQL 2466
>gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 620
Score = 37.0 bits (84), Expect = 0.053
Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 8/154 (5%)
Query: 141 EGPGDPASDEGDGLPGDRPRLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFA 200
+GP + EG L R L+ E Q + ++ LE Q ++E+ L +K D+
Sbjct: 329 KGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELEMQISMRQEMELAMKMLEKDV---C 385
Query: 201 YQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPA 260
++ + SL Q L+ R + EL KL + D+ EL R++ Q+
Sbjct: 386 EKQDALVSLRQQ--LDDLRALKHELAFKLQ---SSDLGVKQKSELNSRLEEKTNQMAATI 440
Query: 261 RVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQT 294
+ EQ + Q + + E+ + + G + +
Sbjct: 441 KQLEQRLRQAERSRQSAELDNRLFKQDFGDKINS 474
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,843,271
Number of Sequences: 37866
Number of extensions: 1229767
Number of successful extensions: 9526
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 257
Number of HSP's that attempted gapping in prelim test: 8939
Number of HSP's gapped (non-prelim): 856
length of query: 613
length of database: 18,247,518
effective HSP length: 108
effective length of query: 505
effective length of database: 14,157,990
effective search space: 7149784950
effective search space used: 7149784950
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.