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Search of human proteins with 170784850
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170784850 SCY1-like 3 isoform 2 [Homo sapiens]
(742 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170784850 SCY1-like 3 isoform 2 [Homo sapiens] 1493 0.0
gi|170784842 SCY1-like 3 isoform 1 [Homo sapiens] 1340 0.0
gi|115430243 SCY1-like 1 isoform B [Homo sapiens] 127 4e-29
gi|115430241 SCY1-like 1 isoform A [Homo sapiens] 127 4e-29
gi|47604944 SCY1-like 2 protein [Homo sapiens] 70 5e-12
gi|41872374 polo-like kinase 3 [Homo sapiens] 54 5e-07
gi|33383239 protein kinase Myt1 isoform 2 [Homo sapiens] 50 6e-06
gi|33383241 protein kinase Myt1 isoform 1 [Homo sapiens] 50 6e-06
gi|93004081 polo-like kinase 2 [Homo sapiens] 46 1e-04
gi|121114283 polo-like kinase 4 [Homo sapiens] 43 0.001
gi|54112407 protein kinase CHK2 isoform c [Homo sapiens] 42 0.003
gi|6005850 protein kinase CHK2 isoform a [Homo sapiens] 42 0.003
gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens] 41 0.004
gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens] 41 0.004
gi|16445033 ACRC protein [Homo sapiens] 38 0.030
gi|28557781 protein kinase C, eta [Homo sapiens] 38 0.039
gi|21359873 polo-like kinase 1 [Homo sapiens] 36 0.11
gi|110349799 testis-specific protein kinase 2 [Homo sapiens] 36 0.11
gi|4503787 fyn-related kinase [Homo sapiens] 36 0.15
gi|27437019 calcium/calmodulin-dependent protein kinase kinase 2... 35 0.25
gi|27437017 calcium/calmodulin-dependent protein kinase kinase 2... 35 0.25
gi|27437015 calcium/calmodulin-dependent protein kinase kinase 2... 35 0.25
gi|27437027 calcium/calmodulin-dependent protein kinase kinase 2... 35 0.25
gi|27437025 calcium/calmodulin-dependent protein kinase kinase 2... 35 0.25
gi|27437023 calcium/calmodulin-dependent protein kinase kinase 2... 35 0.25
gi|27437021 calcium/calmodulin-dependent protein kinase kinase 2... 35 0.25
gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens] 35 0.33
gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens] 35 0.33
gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens] 35 0.33
gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens] 35 0.33
>gi|170784850 SCY1-like 3 isoform 2 [Homo sapiens]
Length = 742
Score = 1493 bits (3864), Expect = 0.0
Identities = 742/742 (100%), Positives = 742/742 (100%)
Query: 1 MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTL 60
MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTL
Sbjct: 1 MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTL 60
Query: 61 RHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHL 120
RHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHL
Sbjct: 61 RHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHL 120
Query: 121 THNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTT 180
THNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTT
Sbjct: 121 THNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTT 180
Query: 181 LPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLL 240
LPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLL
Sbjct: 181 LPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLL 240
Query: 241 SHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVF 300
SHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVF
Sbjct: 241 SHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVF 300
Query: 301 AEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSH 360
AEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSH
Sbjct: 301 AEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSH 360
Query: 361 IEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKI 420
IEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKI
Sbjct: 361 IEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKI 420
Query: 421 FKRTAPSFTKNTDLSLEDSPMCVVCSHHSQISPILENPFSSIFPKCFFSGSTPINSKKHI 480
FKRTAPSFTKNTDLSLEDSPMCVVCSHHSQISPILENPFSSIFPKCFFSGSTPINSKKHI
Sbjct: 421 FKRTAPSFTKNTDLSLEDSPMCVVCSHHSQISPILENPFSSIFPKCFFSGSTPINSKKHI 480
Query: 481 QRDYYNTLLQTGDPFSQPIKFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPEN 540
QRDYYNTLLQTGDPFSQPIKFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPEN
Sbjct: 481 QRDYYNTLLQTGDPFSQPIKFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPEN 540
Query: 541 QTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQK 600
QTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQK
Sbjct: 541 QTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQK 600
Query: 601 PIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFT 660
PIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFT
Sbjct: 601 PIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFT 660
Query: 661 IQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAE 720
IQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAE
Sbjct: 661 IQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAE 720
Query: 721 ITEGEAEGWEEEGELNWEDNNW 742
ITEGEAEGWEEEGELNWEDNNW
Sbjct: 721 ITEGEAEGWEEEGELNWEDNNW 742
>gi|170784842 SCY1-like 3 isoform 1 [Homo sapiens]
Length = 688
Score = 1340 bits (3467), Expect = 0.0
Identities = 684/742 (92%), Positives = 684/742 (92%), Gaps = 54/742 (7%)
Query: 1 MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTL 60
MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTL
Sbjct: 1 MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTL 60
Query: 61 RHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHL 120
RHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHL
Sbjct: 61 RHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHL 120
Query: 121 THNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTT 180
THNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTT
Sbjct: 121 THNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTT 180
Query: 181 LPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLL 240
LPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLL
Sbjct: 181 LPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLL 240
Query: 241 SHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVF 300
SHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVF
Sbjct: 241 SHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVF 300
Query: 301 AEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSH 360
AEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSH
Sbjct: 301 AEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSH 360
Query: 361 IEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKI 420
IEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKI
Sbjct: 361 IEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKI 420
Query: 421 FKRTAPSFTKNTDLSLEDSPMCVVCSHHSQISPILENPFSSIFPKCFFSGSTPINSKKHI 480
FKRTAPSFTKNTDLSLE P S PI
Sbjct: 421 FKRTAPSFTKNTDLSLEGDPF-----------------------------SQPI------ 445
Query: 481 QRDYYNTLLQTGDPFSQPIKFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPEN 540
KFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPEN
Sbjct: 446 -------------------KFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPEN 486
Query: 541 QTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQK 600
QTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQK
Sbjct: 487 QTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQK 546
Query: 601 PIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFT 660
PIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFT
Sbjct: 547 PIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFT 606
Query: 661 IQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAE 720
IQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAE
Sbjct: 607 IQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAE 666
Query: 721 ITEGEAEGWEEEGELNWEDNNW 742
ITEGEAEGWEEEGELNWEDNNW
Sbjct: 667 ITEGEAEGWEEEGELNWEDNNW 688
>gi|115430243 SCY1-like 1 isoform B [Homo sapiens]
Length = 791
Score = 127 bits (319), Expect = 4e-29
Identities = 116/421 (27%), Positives = 185/421 (43%), Gaps = 57/421 (13%)
Query: 34 GKFASVFVYK----RENEDKVNKAA-KHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPL 88
G S+FVY E + +V KAA K KTLRHP +L ++ +H+VTE V PL
Sbjct: 40 GSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLHVVTEAVTPL 99
Query: 89 EVALET------LSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGG 142
+ L+ L E+ G++ I+ AL FL + L HNNVC+++VFV G WKLGG
Sbjct: 100 GIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGG 159
Query: 143 METVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEF-----TTLPECHGH------ARDA 191
++ + S + PP + PE L + G + D
Sbjct: 160 LD--------------YMYSAQGNGGGPPRKGIPELEQYDPPELADSSGRVVREKWSADM 205
Query: 192 FSFGTLV-ESLLTILNEQVSADVLSSFQQTL---HSTLLNPIPKCRPALCTLLSH----- 242
+ G L+ E L + +TL + L+ PK RP L +
Sbjct: 206 WRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPG 265
Query: 243 DFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVFAE 302
F N F+E FL+ + +K EK +FF+ L + E+ +++P LL F
Sbjct: 266 GFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGN 325
Query: 303 PVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSHIE 362
AV + +G LS +Q ++IPV++++F + +R+ LL +E
Sbjct: 326 AGAVVLTPLFKVGK-----------FLSAEEYQQKIIPVVVKMFSSTDRAMRIRLLQQME 374
Query: 363 AYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKIFK 422
++++ + + I P V+ G DT+ +I T+ S+ +L L E + E K F
Sbjct: 375 QFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKSMLLLAPKLN-EANLNVELMKHFA 433
Query: 423 R 423
R
Sbjct: 434 R 434
>gi|115430241 SCY1-like 1 isoform A [Homo sapiens]
Length = 808
Score = 127 bits (319), Expect = 4e-29
Identities = 116/421 (27%), Positives = 185/421 (43%), Gaps = 57/421 (13%)
Query: 34 GKFASVFVYK----RENEDKVNKAA-KHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPL 88
G S+FVY E + +V KAA K KTLRHP +L ++ +H+VTE V PL
Sbjct: 40 GSPVSIFVYDVKPGAEEQTQVAKAAFKRFKTLRHPNILAYIDGLETEKCLHVVTEAVTPL 99
Query: 89 EVALET------LSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGG 142
+ L+ L E+ G++ I+ AL FL + L HNNVC+++VFV G WKLGG
Sbjct: 100 GIYLKARVEAGGLKELEISWGLHQIVKALSFLVNDCSLIHNNVCMAAVFVDRAGEWKLGG 159
Query: 143 METVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEF-----TTLPECHGH------ARDA 191
++ + S + PP + PE L + G + D
Sbjct: 160 LD--------------YMYSAQGNGGGPPRKGIPELEQYDPPELADSSGRVVREKWSADM 205
Query: 192 FSFGTLV-ESLLTILNEQVSADVLSSFQQTL---HSTLLNPIPKCRPALCTLLSH----- 242
+ G L+ E L + +TL + L+ PK RP L +
Sbjct: 206 WRLGCLIWEVFNGPLPRAAALRNPGKIPKTLVPHYCELVGANPKVRPNPARFLQNCRAPG 265
Query: 243 DFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVFAE 302
F N F+E FL+ + +K EK +FF+ L + E+ +++P LL F
Sbjct: 266 GFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGN 325
Query: 303 PVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSHIE 362
AV + +G LS +Q ++IPV++++F + +R+ LL +E
Sbjct: 326 AGAVVLTPLFKVGK-----------FLSAEEYQQKIIPVVVKMFSSTDRAMRIRLLQQME 374
Query: 363 AYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKIFK 422
++++ + + I P V+ G DT+ +I T+ S+ +L L E + E K F
Sbjct: 375 QFIQYLDEPTVNTQIFPHVVHGFLDTNPAIREQTVKSMLLLAPKLN-EANLNVELMKHFA 433
Query: 423 R 423
R
Sbjct: 434 R 434
>gi|47604944 SCY1-like 2 protein [Homo sapiens]
Length = 929
Score = 70.5 bits (171), Expect = 5e-12
Identities = 87/408 (21%), Positives = 162/408 (39%), Gaps = 60/408 (14%)
Query: 48 DKVNKAAKHLKTLRHPCLLRFLSCTVEA-DGIHLVTERV---------------QPLEVA 91
D + + + L LRHP LL E+ D + TE V P+
Sbjct: 84 DSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSPISPD 143
Query: 92 LET--LSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGME---TV 146
++ L E G+ + L FLH + H N+ ++ +++ G WK+ G + +
Sbjct: 144 IKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKIMGFDFCVSS 203
Query: 147 CKVSQATPEFLRSIQSIRDPA-SIP-PEEMSPEFTTLPECHGHARDAFSFGTLVESLLTI 204
S+ P+F P+ +P PE ++PE+ C A D +S GT++ ++
Sbjct: 204 TNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCET-ASDMYSLGTVMYAVFNK 262
Query: 205 ---LNEQVSADVLSSFQQTLHST---------------------LLNPIPKCRPALCTLL 240
+ E D+ SF + L LLN P RP +
Sbjct: 263 GKPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTNIPEEVREHVKLLLNVTPTVRPDADQMT 322
Query: 241 SHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVF 300
FF + + + +L + +K++FFK L + L + +I R++P L ++ F
Sbjct: 323 KIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSE--F 380
Query: 301 AEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEE-HVRMVLLS 359
P V LP +L ++ + E + ++P L +F+ E + ++ L
Sbjct: 381 VNPDMVPFVLPNVLLIAEECTKEE---------YVKLILPELGPVFKQQEPIQILLIFLQ 431
Query: 360 HIEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLL 407
++ + +++K +LP V L S I + L+ + +L+
Sbjct: 432 KMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLI 479
>gi|41872374 polo-like kinase 3 [Homo sapiens]
Length = 646
Score = 53.9 bits (128), Expect = 5e-07
Identities = 57/231 (24%), Positives = 98/231 (42%), Gaps = 32/231 (13%)
Query: 41 VYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPLEVA-----LETL 95
V K +K+ + + L+H ++RF +AD I++ E +A TL
Sbjct: 98 VAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTL 157
Query: 96 SSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPE 155
EV + IL L +LH RG L H ++ L + F++E+ K+G ++ P
Sbjct: 158 LEPEVRYYLRQILSGLKYLHQRGIL-HRDLKLGNFFITENMELKVGDFGLAARLE---PP 213
Query: 156 FLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLLTILNEQVSADVLS 215
R P + PE + L + HG D +S G ++ +LL +AD+
Sbjct: 214 EQRKKTICGTPNYVAPEVL------LRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKE 267
Query: 216 SFQ--QTLHSTL---------------LNPIPKCRPALCTLLSHDFFRNDF 249
+++ + +H TL L P+ RP++ +L HDFF +
Sbjct: 268 TYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGY 318
>gi|33383239 protein kinase Myt1 isoform 2 [Homo sapiens]
Length = 480
Score = 50.4 bits (119), Expect = 6e-06
Identities = 46/166 (27%), Positives = 70/166 (42%), Gaps = 17/166 (10%)
Query: 38 SVFVYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQP-----LEVAL 92
S F ++ K+ + H K +HPC +R E ++L TE P E
Sbjct: 143 SPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEGGILYLQTELCGPSLQQHCEAWG 202
Query: 93 ETLSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQA 152
+L A+V + D LLAL LH +G L H +V +++F+ G KLG + ++ A
Sbjct: 203 ASLPEAQVWGYLRDTLLALAHLHSQG-LVHLDVKPANIFLGPRGRCKLGDFGLLVELGTA 261
Query: 153 TPEFLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLV 198
+ P M+PE L +G A D FS G +
Sbjct: 262 ---------GAGEVQEGDPRYMAPEL--LQGSYGTAADVFSLGLTI 296
>gi|33383241 protein kinase Myt1 isoform 1 [Homo sapiens]
Length = 499
Score = 50.4 bits (119), Expect = 6e-06
Identities = 46/166 (27%), Positives = 70/166 (42%), Gaps = 17/166 (10%)
Query: 38 SVFVYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQP-----LEVAL 92
S F ++ K+ + H K +HPC +R E ++L TE P E
Sbjct: 143 SPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEGGILYLQTELCGPSLQQHCEAWG 202
Query: 93 ETLSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQA 152
+L A+V + D LLAL LH +G L H +V +++F+ G KLG + ++ A
Sbjct: 203 ASLPEAQVWGYLRDTLLALAHLHSQG-LVHLDVKPANIFLGPRGRCKLGDFGLLVELGTA 261
Query: 153 TPEFLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLV 198
+ P M+PE L +G A D FS G +
Sbjct: 262 ---------GAGEVQEGDPRYMAPEL--LQGSYGTAADVFSLGLTI 296
>gi|93004081 polo-like kinase 2 [Homo sapiens]
Length = 685
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/231 (21%), Positives = 98/231 (42%), Gaps = 32/231 (13%)
Query: 41 VYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPLEVA-----LETL 95
V K +K++K + + L H +++F + + I+++ E +A + L
Sbjct: 118 VAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVL 177
Query: 96 SSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPE 155
+ EV + I+ L +LH++ + H ++ L + F++E K+G +
Sbjct: 178 TEPEVRYYLRQIVSGLKYLHEQ-EILHRDLKLGNFFINEAMELKVGDFGLAAR------- 229
Query: 156 FLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLLT------ILNEQV 209
L ++ R P +SPE + HG D ++ G ++ ++L N +
Sbjct: 230 -LEPLEHRRRTICGTPNYLSPEVLN-KQGHGCESDIWALGCVMYTMLLGRPPFETTNLKE 287
Query: 210 SADVLSSFQQTLHSTLLNPI-----------PKCRPALCTLLSHDFFRNDF 249
+ + + T+ S+LL P P+ RP+L ++ HDFF F
Sbjct: 288 TYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGF 338
>gi|121114283 polo-like kinase 4 [Homo sapiens]
Length = 970
Score = 43.1 bits (100), Expect = 0.001
Identities = 54/229 (23%), Positives = 95/229 (41%), Gaps = 37/229 (16%)
Query: 41 VYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERV------QPLEVALET 94
+YK +V K L+HP +L + +++ ++LV E + L+ ++
Sbjct: 48 MYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKP 107
Query: 95 LSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQA 152
S E ++ I+ +++LH G + H ++ LS++ ++ + + K+ G+ T K+
Sbjct: 108 FSENEARHFMHQIITGMLYLHSHG-ILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHE 166
Query: 153 TPEFLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLL---------- 202
L P +SPE T HG D +S G + +LL
Sbjct: 167 KHYTLCG----------TPNYISPEIAT-RSAHGLESDVWSLGCMFYTLLIGRPPFDTDT 215
Query: 203 --TILNEQVSAD-----VLSSFQQTLHSTLLNPIPKCRPALCTLLSHDF 244
LN+ V AD LS + L LL P R +L ++L H F
Sbjct: 216 VKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPF 264
>gi|54112407 protein kinase CHK2 isoform c [Homo sapiens]
Length = 586
Score = 41.6 bits (96), Expect = 0.003
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 16/143 (11%)
Query: 30 VLQDGKFASVFVYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPLE 89
++ KFA + + V + LK L HPC+++ + +A+ ++V E ++ E
Sbjct: 293 IISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGE 351
Query: 90 -----VALETLSSAEVCAGIYDILLALIFLHDRG----HLTHNNVCLSS------VFVSE 134
V + L A Y +LLA+ +LH+ G L NV LSS + +++
Sbjct: 352 LFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITD 411
Query: 135 DGHWKLGGMETVCKVSQATPEFL 157
GH K+ G ++ + TP +L
Sbjct: 412 FGHSKILGETSLMRTLCGTPTYL 434
>gi|6005850 protein kinase CHK2 isoform a [Homo sapiens]
Length = 543
Score = 41.6 bits (96), Expect = 0.003
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 16/143 (11%)
Query: 30 VLQDGKFASVFVYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPLE 89
++ KFA + + V + LK L HPC+++ + +A+ ++V E ++ E
Sbjct: 250 IISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGE 308
Query: 90 -----VALETLSSAEVCAGIYDILLALIFLHDRG----HLTHNNVCLSS------VFVSE 134
V + L A Y +LLA+ +LH+ G L NV LSS + +++
Sbjct: 309 LFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITD 368
Query: 135 DGHWKLGGMETVCKVSQATPEFL 157
GH K+ G ++ + TP +L
Sbjct: 369 FGHSKILGETSLMRTLCGTPTYL 391
>gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]
Length = 1049
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 8/106 (7%)
Query: 43 KRENE--DKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERV-----QPLEVALETL 95
K+ NE + K + L+ LRHP +++ C + LV E LEV + L
Sbjct: 64 KQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPL 123
Query: 96 SSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG 141
E+ A + L L +LH ++ H +V ++ +SE G KLG
Sbjct: 124 QEVEIAAVTHGALQGLAYLHSH-NMIHRDVKAGNILLSEPGLVKLG 168
>gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]
Length = 1235
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 8/106 (7%)
Query: 43 KRENE--DKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERV-----QPLEVALETL 95
K+ NE + K + L+ LRHP +++ C + LV E LEV + L
Sbjct: 64 KQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPL 123
Query: 96 SSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG 141
E+ A + L L +LH ++ H +V ++ +SE G KLG
Sbjct: 124 QEVEIAAVTHGALQGLAYLHSH-NMIHRDVKAGNILLSEPGLVKLG 168
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 38.1 bits (87), Expect = 0.030
Identities = 50/220 (22%), Positives = 87/220 (39%), Gaps = 40/220 (18%)
Query: 507 SDVKNTSEDSENFPSSSKKSEEWPDWS--EPEEPENQTVNIQIWPREPCDDVKSQCTTLD 564
SDV + S D + P S E PD S + E P++ + + + P + DD ++ + D
Sbjct: 222 SDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEA-PDDSSDDSEAPDDSSD 280
Query: 565 VEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQKPIPALLSLTEESMPWKSSLPQKI- 623
E+S D SS D++ + + P + +P S + +P +S ++
Sbjct: 281 DSEASDD----SSDDSEASDDSSDDSEAPDDKSDDSDVPEDKS-DDSDVPDDNSDDLEVP 335
Query: 624 ----SLVQRG----DDADQIEPPKVSSQERPLKVPSELGLGEEFTIQVKKKPVKDPEMDW 675
L G D+ + +E SQ E LGE + KP DPE +
Sbjct: 336 VPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLS-----KPPSDPEAN- 389
Query: 676 FADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSK 715
PE+ +P +++ +PV++ S K
Sbjct: 390 -----------------PEVSERKLPTEEEPAPVVEQSGK 412
>gi|28557781 protein kinase C, eta [Homo sapiens]
Length = 683
Score = 37.7 bits (86), Expect = 0.039
Identities = 42/148 (28%), Positives = 66/148 (44%), Gaps = 18/148 (12%)
Query: 23 GLAVYPAVLQDGKFASVFVYKRE---NEDKVNKAAKHLKTL----RHPCLLRFLSCTVEA 75
G + V + G +V V K++ +D V + L HP L + C
Sbjct: 367 GKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTP 426
Query: 76 DGIHLVTERVQPLEVALETLSSA---EVCAGIY--DILLALIFLHDRGHLTHNNVCLSSV 130
D + V E V ++ S E A Y +I+ AL+FLHD+G + + ++ L +V
Sbjct: 427 DRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKG-IIYRDLKLDNV 485
Query: 131 FVSEDGHWKLG--GM--ETVCK-VSQAT 153
+ +GH KL GM E +C V+ AT
Sbjct: 486 LLDHEGHCKLADFGMCKEGICNGVTTAT 513
>gi|21359873 polo-like kinase 1 [Homo sapiens]
Length = 603
Score = 36.2 bits (82), Expect = 0.11
Identities = 50/230 (21%), Positives = 91/230 (39%), Gaps = 32/230 (13%)
Query: 43 KRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQ-----PLEVALETLSS 97
K +K++ ++L H ++ F + D + +V E + L + L+
Sbjct: 91 KPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTE 150
Query: 98 AEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFL 157
E + I+L +LH R + H ++ L ++F++ED K+G KV +
Sbjct: 151 PEARYYLRQIVLGCQYLH-RNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEY---DGE 206
Query: 158 RSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLL-------------TI 204
R P I PE +S + H D +S G ++ +LL T
Sbjct: 207 RKKTLCGTPNYIAPEVLS------KKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETY 260
Query: 205 L----NEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLLSHDFFRNDFL 250
L NE ++ +L +L P RP + LL+ +FF + ++
Sbjct: 261 LRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYI 310
>gi|110349799 testis-specific protein kinase 2 [Homo sapiens]
Length = 571
Score = 36.2 bits (82), Expect = 0.11
Identities = 50/239 (20%), Positives = 96/239 (40%), Gaps = 25/239 (10%)
Query: 46 NEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQP--LEVALETLSSAEVCAG 103
N + K + + L HP +LRF+ V +H +TE + LE L++
Sbjct: 94 NRANMLKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNLHLPWTVR 153
Query: 104 I---YDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCK---VSQATPEFL 157
+ YDI + L +LH +G + H ++ + + D + G V +++ P+
Sbjct: 154 VKLAYDIAVGLSYLHFKG-IFHRDLTSKNCLIKRDEN----GYSAVVADFGLAEKIPDVS 208
Query: 158 RSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSF 217
+ + S P M+PE E + D FS+G ++ ++ + Q D L
Sbjct: 209 MGSEKLAVVGS--PFWMAPE-VLRDEPYNEKADVFSYGIILCEIIARI--QADPDYLPRT 263
Query: 218 QQ--TLHSTLLNPIPKCRPALCTLLSH-----DFFRNDFLEVVNFLKSLTLKSEEEKTE 269
+ + + + C P L + R F+E+ L+ + + +EE+ E
Sbjct: 264 ENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEEILSRLQEEEQE 322
>gi|4503787 fyn-related kinase [Homo sapiens]
Length = 505
Score = 35.8 bits (81), Expect = 0.15
Identities = 55/246 (22%), Positives = 101/246 (41%), Gaps = 56/246 (22%)
Query: 52 KAAKHLKTLRHPCLLR-FLSCTVEADGIHLVTERVQ--------------PLEVALETLS 96
+ A+ +K LRHP L++ + CT+E D I+++TE ++ + + +
Sbjct: 276 REAQIMKNLRHPKLIQLYAVCTLE-DPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDM 334
Query: 97 SAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQATP 154
+A+V +G + +L R ++ H ++ +V V E +K+ G+ V KV
Sbjct: 335 AAQVASG-------MAYLESRNYI-HRDLAARNVLVGEHNIYKVADFGLARVFKVDN--- 383
Query: 155 EFLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLLT----------- 203
I R +P + +PE D +SFG L+ ++T
Sbjct: 384 ---EDIYESRHEIKLPVKWTAPE-AIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTG 439
Query: 204 -----ILNEQVSADVLSSFQQTLHSTLL---NPIPKCRPALCTL--LSHDFFRND--FLE 251
+L + S+ Q ++ +L N PK RP TL D+F D + +
Sbjct: 440 AQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFETDSSYSD 499
Query: 252 VVNFLK 257
NF++
Sbjct: 500 ANNFIR 505
>gi|27437019 calcium/calmodulin-dependent protein kinase kinase 2
beta isoform 4 [Homo sapiens]
Length = 498
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 57 LKTLRHPCLLRFLSCTVEA--DGIHLVTERVQP---LEV-ALETLSSAEVCAGIYDILLA 110
LK L HP +++ + + D +++V E V +EV L+ LS + D++
Sbjct: 240 LKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKG 299
Query: 111 LIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQATPEFLRSIQSIRDPAS 168
+ +LH + + H ++ S++ V EDGH K+ G+ K S A ++ PA
Sbjct: 300 IEYLHYQ-KIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLS-----NTVGTPAF 353
Query: 169 IPPEEMSPEFTTLPECHGHARDAFSFG 195
+ PE +S T G A D ++ G
Sbjct: 354 MAPESLS---ETRKIFSGKALDVWAMG 377
>gi|27437017 calcium/calmodulin-dependent protein kinase kinase 2
beta isoform 2 [Homo sapiens]
Length = 541
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 57 LKTLRHPCLLRFLSCTVEA--DGIHLVTERVQP---LEV-ALETLSSAEVCAGIYDILLA 110
LK L HP +++ + + D +++V E V +EV L+ LS + D++
Sbjct: 240 LKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKG 299
Query: 111 LIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQATPEFLRSIQSIRDPAS 168
+ +LH + + H ++ S++ V EDGH K+ G+ K S A ++ PA
Sbjct: 300 IEYLHYQ-KIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLS-----NTVGTPAF 353
Query: 169 IPPEEMSPEFTTLPECHGHARDAFSFG 195
+ PE +S T G A D ++ G
Sbjct: 354 MAPESLS---ETRKIFSGKALDVWAMG 377
>gi|27437015 calcium/calmodulin-dependent protein kinase kinase 2
beta isoform 1 [Homo sapiens]
Length = 588
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 57 LKTLRHPCLLRFLSCTVEA--DGIHLVTERVQP---LEV-ALETLSSAEVCAGIYDILLA 110
LK L HP +++ + + D +++V E V +EV L+ LS + D++
Sbjct: 240 LKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKG 299
Query: 111 LIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQATPEFLRSIQSIRDPAS 168
+ +LH + + H ++ S++ V EDGH K+ G+ K S A ++ PA
Sbjct: 300 IEYLHYQ-KIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLS-----NTVGTPAF 353
Query: 169 IPPEEMSPEFTTLPECHGHARDAFSFG 195
+ PE +S T G A D ++ G
Sbjct: 354 MAPESLS---ETRKIFSGKALDVWAMG 377
>gi|27437027 calcium/calmodulin-dependent protein kinase kinase 2
beta isoform 2 [Homo sapiens]
Length = 541
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 57 LKTLRHPCLLRFLSCTVEA--DGIHLVTERVQP---LEV-ALETLSSAEVCAGIYDILLA 110
LK L HP +++ + + D +++V E V +EV L+ LS + D++
Sbjct: 240 LKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKG 299
Query: 111 LIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQATPEFLRSIQSIRDPAS 168
+ +LH + + H ++ S++ V EDGH K+ G+ K S A ++ PA
Sbjct: 300 IEYLHYQ-KIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLS-----NTVGTPAF 353
Query: 169 IPPEEMSPEFTTLPECHGHARDAFSFG 195
+ PE +S T G A D ++ G
Sbjct: 354 MAPESLS---ETRKIFSGKALDVWAMG 377
>gi|27437025 calcium/calmodulin-dependent protein kinase kinase 2
beta isoform 3 [Homo sapiens]
Length = 545
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 57 LKTLRHPCLLRFLSCTVEA--DGIHLVTERVQP---LEV-ALETLSSAEVCAGIYDILLA 110
LK L HP +++ + + D +++V E V +EV L+ LS + D++
Sbjct: 240 LKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKG 299
Query: 111 LIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQATPEFLRSIQSIRDPAS 168
+ +LH + + H ++ S++ V EDGH K+ G+ K S A ++ PA
Sbjct: 300 IEYLHYQ-KIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLS-----NTVGTPAF 353
Query: 169 IPPEEMSPEFTTLPECHGHARDAFSFG 195
+ PE +S T G A D ++ G
Sbjct: 354 MAPESLS---ETRKIFSGKALDVWAMG 377
>gi|27437023 calcium/calmodulin-dependent protein kinase kinase 2
beta isoform 6 [Homo sapiens]
Length = 490
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 57 LKTLRHPCLLRFLSCTVEA--DGIHLVTERVQP---LEV-ALETLSSAEVCAGIYDILLA 110
LK L HP +++ + + D +++V E V +EV L+ LS + D++
Sbjct: 240 LKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKG 299
Query: 111 LIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQATPEFLRSIQSIRDPAS 168
+ +LH + + H ++ S++ V EDGH K+ G+ K S A ++ PA
Sbjct: 300 IEYLHYQ-KIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLS-----NTVGTPAF 353
Query: 169 IPPEEMSPEFTTLPECHGHARDAFSFG 195
+ PE +S T G A D ++ G
Sbjct: 354 MAPESLS---ETRKIFSGKALDVWAMG 377
>gi|27437021 calcium/calmodulin-dependent protein kinase kinase 2
beta isoform 5 [Homo sapiens]
Length = 533
Score = 35.0 bits (79), Expect = 0.25
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 17/147 (11%)
Query: 57 LKTLRHPCLLRFLSCTVEA--DGIHLVTERVQP---LEV-ALETLSSAEVCAGIYDILLA 110
LK L HP +++ + + D +++V E V +EV L+ LS + D++
Sbjct: 240 LKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKG 299
Query: 111 LIFLHDRGHLTHNNVCLSSVFVSEDGHWKLG--GMETVCKVSQATPEFLRSIQSIRDPAS 168
+ +LH + + H ++ S++ V EDGH K+ G+ K S A ++ PA
Sbjct: 300 IEYLHYQ-KIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLS-----NTVGTPAF 353
Query: 169 IPPEEMSPEFTTLPECHGHARDAFSFG 195
+ PE +S T G A D ++ G
Sbjct: 354 MAPESLS---ETRKIFSGKALDVWAMG 377
>gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens]
Length = 967
Score = 34.7 bits (78), Expect = 0.33
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 115 HDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKV-SQATPEFLRSIQSIRDPASIPPEE 173
++R HLT +++ + + T K S +TP F SI + + PP
Sbjct: 492 YNRDHLTQFTSLITTTKTTSHSPPSFTALITSTKTTSHSTPSFTSSIATTETTSHSPPSF 551
Query: 174 MSPEFTTLPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHST 224
S TT E H H+ FS ++ S T + +++ + TLHST
Sbjct: 552 TSSSTTT--ETHSHSTPGFS-SSIATSKTTSTSPPRFTFAIATTKTTLHST 599
>gi|41281753 NIMA-related kinase 11 isoform 2 [Homo sapiens]
Length = 470
Score = 34.7 bits (78), Expect = 0.33
Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 37/164 (22%)
Query: 3 SENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVY-----KRENEDKV------- 50
S ++A+ +Y P TL + V L G F +V++ KR E KV
Sbjct: 12 SGSTAISTY-----PKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVG 66
Query: 51 ----------NKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTE---------RVQPLEVA 91
N A+ L L HP +++F + VE D ++TE ++Q + A
Sbjct: 67 ELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQA 126
Query: 92 LETLSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSED 135
+ ++ +LL + ++H+R + H ++ +VF+ +
Sbjct: 127 GKIFPENQIIEWFIQLLLGVDYMHER-RILHRDLKSKNVFLKNN 169
>gi|225637562 NIMA-related kinase 11 isoform 3 [Homo sapiens]
Length = 599
Score = 34.7 bits (78), Expect = 0.33
Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 37/164 (22%)
Query: 3 SENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVY-----KRENEDKV------- 50
S ++A+ +Y P TL + V L G F +V++ KR E KV
Sbjct: 12 SGSTAISTY-----PKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVG 66
Query: 51 ----------NKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTE---------RVQPLEVA 91
N A+ L L HP +++F + VE D ++TE ++Q + A
Sbjct: 67 ELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQA 126
Query: 92 LETLSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSED 135
+ ++ +LL + ++H+R + H ++ +VF+ +
Sbjct: 127 GKIFPENQIIEWFIQLLLGVDYMHER-RILHRDLKSKNVFLKNN 169
>gi|225637560 NIMA-related kinase 11 isoform 1 [Homo sapiens]
Length = 645
Score = 34.7 bits (78), Expect = 0.33
Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 37/164 (22%)
Query: 3 SENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVY-----KRENEDKV------- 50
S ++A+ +Y P TL + V L G F +V++ KR E KV
Sbjct: 12 SGSTAISTY-----PKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVG 66
Query: 51 ----------NKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTE---------RVQPLEVA 91
N A+ L L HP +++F + VE D ++TE ++Q + A
Sbjct: 67 ELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQA 126
Query: 92 LETLSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSED 135
+ ++ +LL + ++H+R + H ++ +VF+ +
Sbjct: 127 GKIFPENQIIEWFIQLLLGVDYMHER-RILHRDLKSKNVFLKNN 169
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,300,504
Number of Sequences: 37866
Number of extensions: 1453325
Number of successful extensions: 4418
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 4349
Number of HSP's gapped (non-prelim): 155
length of query: 742
length of database: 18,247,518
effective HSP length: 110
effective length of query: 632
effective length of database: 14,082,258
effective search space: 8899987056
effective search space used: 8899987056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.