Guide to the Human Genome
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Search of human proteins with 112421108

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112421108 capicua homolog [Homo sapiens]
         (1608 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112421108 capicua homolog [Homo sapiens]                          3256   0.0  
gi|169172340 PREDICTED: hypothetical protein LOC442676 [Homo sap...   249   1e-65
gi|169170016 PREDICTED: hypothetical protein LOC442676 [Homo sap...   249   1e-65
gi|239508816 PREDICTED: hypothetical protein LOC442676 [Homo sap...   249   1e-65
gi|169171742 PREDICTED: hypothetical protein LOC442676 [Homo sap...   247   6e-65
gi|239740980 PREDICTED: hypothetical protein XP_002344293 [Homo ...   223   2e-57
gi|169171432 PREDICTED: similar to hCG2014367 [Homo sapiens]          221   3e-57
gi|169171899 PREDICTED: similar to hCG2014367 [Homo sapiens]          221   3e-57
gi|169171130 PREDICTED: hypothetical protein LOC100130600 [Homo ...   221   3e-57
gi|239509024 PREDICTED: similar to hCG2014367 [Homo sapiens]          221   3e-57
gi|239753062 PREDICTED: hypothetical protein [Homo sapiens]           211   3e-54
gi|239742769 PREDICTED: hypothetical protein XP_002342619 [Homo ...   197   9e-50
gi|163965366 nascent polypeptide-associated complex alpha subuni...   176   2e-43
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   154   9e-37
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   142   2e-33
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...   138   5e-32
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]        129   2e-29
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...   126   2e-28
gi|239747616 PREDICTED: similar to hCG1996386 [Homo sapiens]          120   1e-26
gi|169162775 PREDICTED: similar to hCG1996386 [Homo sapiens]          120   1e-26
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]        116   2e-25
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  116   2e-25
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  116   2e-25
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  116   2e-25
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   116   2e-25
gi|116284392 mucin 2 precursor [Homo sapiens]                         116   2e-25
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa...   110   1e-23
gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo sap...   110   1e-23
gi|153792074 proline rich 12 [Homo sapiens]                           109   2e-23
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     106   2e-22

>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 3256 bits (8442), Expect = 0.0
 Identities = 1608/1608 (100%), Positives = 1608/1608 (100%)

Query: 1    MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQ 60
            MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQ
Sbjct: 1    MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQ 60

Query: 61   PASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESG 120
            PASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESG
Sbjct: 61   PASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESG 120

Query: 121  KGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKE 180
            KGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKE
Sbjct: 121  KGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKE 180

Query: 181  RDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYA 240
            RDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYA
Sbjct: 181  RDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYA 240

Query: 241  LGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSM 300
            LGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSM
Sbjct: 241  LGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSM 300

Query: 301  SETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGV 360
            SETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGV
Sbjct: 301  SETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGV 360

Query: 361  HSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLP 420
            HSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLP
Sbjct: 361  HSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLP 420

Query: 421  TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSS 480
            TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSS
Sbjct: 421  TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSS 480

Query: 481  GEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPA 540
            GEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPA
Sbjct: 481  GEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPA 540

Query: 541  SSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRR 600
            SSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRR
Sbjct: 541  SSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRR 600

Query: 601  KRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAP 660
            KRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAP
Sbjct: 601  KRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAP 660

Query: 661  AAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGG 720
            AAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGG
Sbjct: 661  AAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGG 720

Query: 721  SPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQF 780
            SPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQF
Sbjct: 721  SPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQF 780

Query: 781  IAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAP 840
            IAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAP
Sbjct: 781  IAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAP 840

Query: 841  APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKA 900
            APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKA
Sbjct: 841  APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKA 900

Query: 901  QSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPP 960
            QSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPP
Sbjct: 901  QSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPP 960

Query: 961  SKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTS 1020
            SKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTS
Sbjct: 961  SKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTS 1020

Query: 1021 PASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQL 1080
            PASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQL
Sbjct: 1021 PASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQL 1080

Query: 1081 PPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPA 1140
            PPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPA
Sbjct: 1081 PPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPA 1140

Query: 1141 PATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRP 1200
            PATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRP
Sbjct: 1141 PATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRP 1200

Query: 1201 GPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAK 1260
            GPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAK
Sbjct: 1201 GPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAK 1260

Query: 1261 GPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPE 1320
            GPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPE
Sbjct: 1261 GPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPE 1320

Query: 1321 RKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLA 1380
            RKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLA
Sbjct: 1321 RKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLA 1380

Query: 1381 TSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFD 1440
            TSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFD
Sbjct: 1381 TSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFD 1440

Query: 1441 RTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADI 1500
            RTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADI
Sbjct: 1441 RTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADI 1500

Query: 1501 FPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPT 1560
            FPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPT
Sbjct: 1501 FPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPT 1560

Query: 1561 SPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608
            SPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR
Sbjct: 1561 SPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608


>gi|169172340 PREDICTED: hypothetical protein LOC442676 [Homo
           sapiens]
          Length = 679

 Score =  249 bits (637), Expect = 1e-65
 Identities = 147/300 (49%), Positives = 172/300 (57%), Gaps = 41/300 (13%)

Query: 41  VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGA 100
           VP +    PDPS+QP EA+QPASH VASNQSK+PA+ AAVAHERPPGGTGS DP RPPGA
Sbjct: 222 VPLVLCPLPDPSLQPHEARQPASHSVASNQSKQPAKLAAVAHERPPGGTGSVDPGRPPGA 281

Query: 101 TCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEI 160
           TCPESPGPG PH LGVVE GK PPPT EEE   P G P   +                  
Sbjct: 282 TCPESPGPGTPHTLGVVEPGKSPPPTMEEEPWAPKGSPCWTA------------------ 323

Query: 161 QLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRH--RALV 218
                      QSLSAL KE+DSSS+KDG SPNK +KDHIR PM+      +        
Sbjct: 324 -----------QSLSALRKEQDSSSKKDGHSPNKWDKDHIRWPMSGGHELQQAAPGSGRA 372

Query: 219 HQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSS 278
           HQ HPNQDN TVS+IL + WY LGP E QKYHDLAFQVK AH +  P          K  
Sbjct: 373 HQGHPNQDNWTVSQILSKRWYTLGPNETQKYHDLAFQVKVAHLQQGPKEVQLRGQAHKPG 432

Query: 279 SEAKPTSLGLAGGHKETRERSM---SETGTAAAPGVSSELLSVAAQTLLSSD---TKAPG 332
           +      L +A     + E  M    E G      +S  ++++A  TL+SS    ++ PG
Sbjct: 433 ASRTVQGLHMASEDTASDEEPMVIHEEEGVT----MSLLMMALAPLTLISSSRSHSRPPG 488



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 33/82 (40%), Positives = 39/82 (47%), Gaps = 13/82 (15%)

Query: 1518 IMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP 1577
            ++ ++    +PPG   PL   PP      P P   P GGPDPTSP SDS  A  APPLP 
Sbjct: 476  LISSSRSHSRPPG---PLCTHPPLQGFFCPCPDSQPCGGPDPTSPGSDSDAALDAPPLPL 532

Query: 1578 PPESGPGQPGWEGAPQPSPPPP 1599
            P          E  P  +PP P
Sbjct: 533  P----------ESHPCLTPPHP 544



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 19/100 (19%)

Query: 421 TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSS 480
           +R  +    ASED  SDEE MVI EEEG           T  + +     +T   S  S 
Sbjct: 434 SRTVQGLHMASEDTASDEEPMVIHEEEG----------VTMSLLMMALAPLTLISSSRSH 483

Query: 481 GEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDP 520
              P      G     P ++  F  C    D +P G PDP
Sbjct: 484 SRPP------GPLCTHPPLQGFFCPCP---DSQPCGGPDP 514


>gi|169170016 PREDICTED: hypothetical protein LOC442676 [Homo
           sapiens]
          Length = 679

 Score =  249 bits (637), Expect = 1e-65
 Identities = 147/300 (49%), Positives = 172/300 (57%), Gaps = 41/300 (13%)

Query: 41  VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGA 100
           VP +    PDPS+QP EA+QPASH VASNQSK+PA+ AAVAHERPPGGTGS DP RPPGA
Sbjct: 222 VPLVLCPLPDPSLQPHEARQPASHSVASNQSKQPAKLAAVAHERPPGGTGSVDPGRPPGA 281

Query: 101 TCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEI 160
           TCPESPGPG PH LGVVE GK PPPT EEE   P G P   +                  
Sbjct: 282 TCPESPGPGTPHTLGVVEPGKSPPPTMEEEPWAPKGSPCWTA------------------ 323

Query: 161 QLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRH--RALV 218
                      QSLSAL KE+DSSS+KDG SPNK +KDHIR PM+      +        
Sbjct: 324 -----------QSLSALRKEQDSSSKKDGHSPNKWDKDHIRWPMSGGHELQQAAPGSGRA 372

Query: 219 HQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSS 278
           HQ HPNQDN TVS+IL + WY LGP E QKYHDLAFQVK AH +  P          K  
Sbjct: 373 HQGHPNQDNWTVSQILSKRWYTLGPNETQKYHDLAFQVKVAHLQQGPKEVQLRGQAHKPG 432

Query: 279 SEAKPTSLGLAGGHKETRERSM---SETGTAAAPGVSSELLSVAAQTLLSSD---TKAPG 332
           +      L +A     + E  M    E G      +S  ++++A  TL+SS    ++ PG
Sbjct: 433 ASRTVQGLHMASEDTASDEEPMVIHEEEGVT----MSLLMMALAPLTLISSSRSHSRPPG 488



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 33/82 (40%), Positives = 39/82 (47%), Gaps = 13/82 (15%)

Query: 1518 IMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP 1577
            ++ ++    +PPG   PL   PP      P P   P GGPDPTSP SDS  A  APPLP 
Sbjct: 476  LISSSRSHSRPPG---PLCTHPPLQGFFCPCPDSQPCGGPDPTSPGSDSDAALDAPPLPL 532

Query: 1578 PPESGPGQPGWEGAPQPSPPPP 1599
            P          E  P  +PP P
Sbjct: 533  P----------ESHPCLTPPHP 544



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 19/100 (19%)

Query: 421 TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSS 480
           +R  +    ASED  SDEE MVI EEEG           T  + +     +T   S  S 
Sbjct: 434 SRTVQGLHMASEDTASDEEPMVIHEEEG----------VTMSLLMMALAPLTLISSSRSH 483

Query: 481 GEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDP 520
              P      G     P ++  F  C    D +P G PDP
Sbjct: 484 SRPP------GPLCTHPPLQGFFCPCP---DSQPCGGPDP 514


>gi|239508816 PREDICTED: hypothetical protein LOC442676 [Homo
           sapiens]
          Length = 679

 Score =  249 bits (637), Expect = 1e-65
 Identities = 147/300 (49%), Positives = 172/300 (57%), Gaps = 41/300 (13%)

Query: 41  VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGA 100
           VP +    PDPS+QP EA+QPASH VASNQSK+PA+ AAVAHERPPGGTGS DP RPPGA
Sbjct: 222 VPLVLCPLPDPSLQPHEARQPASHSVASNQSKQPAKLAAVAHERPPGGTGSVDPGRPPGA 281

Query: 101 TCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEI 160
           TCPESPGPG PH LGVVE GK PPPT EEE   P G P   +                  
Sbjct: 282 TCPESPGPGTPHTLGVVEPGKSPPPTMEEEPWAPKGSPCWTA------------------ 323

Query: 161 QLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRH--RALV 218
                      QSLSAL KE+DSSS+KDG SPNK +KDHIR PM+      +        
Sbjct: 324 -----------QSLSALRKEQDSSSKKDGHSPNKWDKDHIRWPMSGGHELQQAAPGSGRA 372

Query: 219 HQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSS 278
           HQ HPNQDN TVS+IL + WY LGP E QKYHDLAFQVK AH +  P          K  
Sbjct: 373 HQGHPNQDNWTVSQILSKRWYTLGPNETQKYHDLAFQVKVAHLQQGPKEVQLRGQAHKPG 432

Query: 279 SEAKPTSLGLAGGHKETRERSM---SETGTAAAPGVSSELLSVAAQTLLSSD---TKAPG 332
           +      L +A     + E  M    E G      +S  ++++A  TL+SS    ++ PG
Sbjct: 433 ASRTVQGLHMASEDTASDEEPMVIHEEEGVT----MSLLMMALAPLTLISSSRSHSRPPG 488



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 33/82 (40%), Positives = 39/82 (47%), Gaps = 13/82 (15%)

Query: 1518 IMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP 1577
            ++ ++    +PPG   PL   PP      P P   P GGPDPTSP SDS  A  APPLP 
Sbjct: 476  LISSSRSHSRPPG---PLCTHPPLQGFFCPCPDSQPCGGPDPTSPGSDSDAALDAPPLPL 532

Query: 1578 PPESGPGQPGWEGAPQPSPPPP 1599
            P          E  P  +PP P
Sbjct: 533  P----------ESHPCLTPPHP 544



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 19/100 (19%)

Query: 421 TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSS 480
           +R  +    ASED  SDEE MVI EEEG           T  + +     +T   S  S 
Sbjct: 434 SRTVQGLHMASEDTASDEEPMVIHEEEG----------VTMSLLMMALAPLTLISSSRSH 483

Query: 481 GEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDP 520
              P      G     P ++  F  C    D +P G PDP
Sbjct: 484 SRPP------GPLCTHPPLQGFFCPCP---DSQPCGGPDP 514


>gi|169171742 PREDICTED: hypothetical protein LOC442676 [Homo
           sapiens]
          Length = 679

 Score =  247 bits (631), Expect = 6e-65
 Identities = 146/300 (48%), Positives = 171/300 (57%), Gaps = 41/300 (13%)

Query: 41  VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGA 100
           VP +    PDPS+QP EA+QPASH VASNQSK+PA+ AAVAHERPPGGTGS DP RPPGA
Sbjct: 222 VPLVLCPLPDPSLQPHEARQPASHSVASNQSKQPAKLAAVAHERPPGGTGSVDPGRPPGA 281

Query: 101 TCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEI 160
           TCPESPGPG PH LGVVE GK PPPT EEE   P G P   +                  
Sbjct: 282 TCPESPGPGTPHTLGVVEPGKSPPPTMEEEPWAPQGSPCWTA------------------ 323

Query: 161 QLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRH--RALV 218
                      QSLSAL KE+DSSS+KDG SPNK +KDHIR PM+      +        
Sbjct: 324 -----------QSLSALRKEQDSSSKKDGHSPNKWDKDHIRWPMSGGHELQQAAPGSGRA 372

Query: 219 HQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSS 278
           HQ HPNQDN TVS+IL + WY LGP E QKYHD AFQVK AH +  P          K  
Sbjct: 373 HQGHPNQDNWTVSQILSKRWYTLGPNETQKYHDQAFQVKVAHLQQGPKEVQLRGQAHKPG 432

Query: 279 SEAKPTSLGLAGGHKETRERSM---SETGTAAAPGVSSELLSVAAQTLLSSD---TKAPG 332
           +      L +A     + E  M    E G      +S  ++++A  TL+SS    ++ PG
Sbjct: 433 ASRTVQGLHMASEDTASDEEPMVIHEEEGVT----MSLLMMALAPLTLISSSRSHSRPPG 488



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 33/82 (40%), Positives = 39/82 (47%), Gaps = 13/82 (15%)

Query: 1518 IMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP 1577
            ++ ++    +PPG   PL   PP      P P   P GGPDPTSP SDS  A  APPLP 
Sbjct: 476  LISSSRSHSRPPG---PLCTHPPLQGFFCPCPDSQPCGGPDPTSPGSDSDAALDAPPLPL 532

Query: 1578 PPESGPGQPGWEGAPQPSPPPP 1599
            P          E  P  +PP P
Sbjct: 533  P----------ESHPCLTPPHP 544



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 19/100 (19%)

Query: 421 TRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSS 480
           +R  +    ASED  SDEE MVI EEEG           T  + +     +T   S  S 
Sbjct: 434 SRTVQGLHMASEDTASDEEPMVIHEEEG----------VTMSLLMMALAPLTLISSSRSH 483

Query: 481 GEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDP 520
              P      G     P ++  F  C    D +P G PDP
Sbjct: 484 SRPP------GPLCTHPPLQGFFCPCP---DSQPCGGPDP 514


>gi|239740980 PREDICTED: hypothetical protein XP_002344293 [Homo
           sapiens]
          Length = 616

 Score =  223 bits (567), Expect = 2e-57
 Identities = 137/238 (57%), Positives = 153/238 (64%), Gaps = 40/238 (16%)

Query: 172 QSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRAL--VHQRHPNQDNRT 229
           QSLSAL KE+DSSSEKDGRSPNK +KDHIR PM+      +        HQ HPNQDNRT
Sbjct: 104 QSLSALRKEQDSSSEKDGRSPNKSDKDHIRWPMSGAHDLQQAAPGPGGAHQGHPNQDNRT 163

Query: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLA 289
           VS++L E WY LGP E QKY +LAFQ              CNK                 
Sbjct: 164 VSQMLSERWYTLGPNEMQKY-NLAFQE-------------CNKG---------------- 193

Query: 290 GGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGS 349
                + ERS+SETGTA APGVSSELLSVAAQTL SSDTK       G    H+  G   
Sbjct: 194 -----SWERSISETGTATAPGVSSELLSVAAQTLQSSDTKE--QLLWGRTAAHS-QGTWL 245

Query: 350 ARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEG 407
           +  +AFSHSGVHSLDG E+D QAL+ELTQ+VSG ASYSGPKPSTQ+GAPG FAAPGEG
Sbjct: 246 SLAQAFSHSGVHSLDGREIDRQALRELTQVVSGTASYSGPKPSTQHGAPGHFAAPGEG 303



 Score =  103 bits (257), Expect = 1e-21
 Identities = 78/208 (37%), Positives = 86/208 (41%), Gaps = 62/208 (29%)

Query: 1379 LATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFT 1438
            L   P  +    R  R N TD+D   EDPT+PK K RR SSCS +PNTPK A C+GD F 
Sbjct: 349  LRPQPLGMGAQGRLPRGNPTDMDPTLEDPTAPKCKTRRCSSCSPKPNTPKCAMCDGDSFP 408

Query: 1439 FDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYA 1498
            F  TG EAED L E E +K   SSL                         ATAA QA YA
Sbjct: 409  FACTGGEAEDRLREPETEKALSSSL------------------------HATAALQAHYA 444

Query: 1499 DIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPD 1558
             IFPSKVC                                      +APA TPSP G   
Sbjct: 445  HIFPSKVC--------------------------------------SAPALTPSPVGVLT 466

Query: 1559 PTSPSSDSGTAQAAPPLPPPPESGPGQP 1586
                +     A AAPPL  P     GQP
Sbjct: 467  APHLAQTLDAALAAPPLLLPESHAGGQP 494



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 40/66 (60%), Positives = 42/66 (63%), Gaps = 2/66 (3%)

Query: 516 GPPDPPVAFGKG-YGSAPSSSAS-SPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRP 573
           G P    A G+G YG   SSS + S ASSS  A TSF LG G FKAQESGQ S AGPLRP
Sbjct: 292 GAPGHFAAPGEGVYGHTLSSSYTYSDASSSTLAPTSFLLGPGAFKAQESGQRSRAGPLRP 351

Query: 574 PPPGAG 579
            P G G
Sbjct: 352 QPLGMG 357



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 28/57 (49%), Positives = 34/57 (59%), Gaps = 9/57 (15%)

Query: 10 PASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPV 66
          PA S ASRG+ MFVW NVE  S AVF W+S +PFL P        P    +P++ PV
Sbjct: 34 PAFSEASRGVSMFVWRNVEGHSAAVFSWYS-IPFLTP--------PCSHTRPSNLPV 81


>gi|169171432 PREDICTED: similar to hCG2014367 [Homo sapiens]
          Length = 594

 Score =  221 bits (564), Expect = 3e-57
 Identities = 136/244 (55%), Positives = 151/244 (61%), Gaps = 39/244 (15%)

Query: 172 QSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRA--LVHQRHPNQDNRT 229
           QSLSAL KE+DSSSEKDG SPNK +KDHIR PM+      +        HQ HPNQDNRT
Sbjct: 80  QSLSALRKEQDSSSEKDGCSPNKWDKDHIRWPMSGGHDLQQAAPGPGRAHQGHPNQDNRT 139

Query: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLA 289
           VS++L + WY LGP E QKYHDLAFQ              CNK                 
Sbjct: 140 VSQMLSKRWYTLGPNETQKYHDLAFQE-------------CNKG---------------- 170

Query: 290 GGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGS 349
                + ER +SETGTA APGVSSELLSVAAQTL SSDTK       G    H+  G   
Sbjct: 171 -----SWERRISETGTATAPGVSSELLSVAAQTLQSSDTKE--QLLWGRMAAHS-QGTWL 222

Query: 350 ARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGA 409
           +  +AFSHSGVHSLDG E+D QAL+ELTQ+VSG ASYSGPKPSTQYGAPG FAAP  G  
Sbjct: 223 SLAQAFSHSGVHSLDGREIDRQALRELTQVVSGTASYSGPKPSTQYGAPGHFAAPAFGKV 282

Query: 410 LAAT 413
              T
Sbjct: 283 YGPT 286



 Score =  104 bits (260), Expect = 6e-22
 Identities = 76/196 (38%), Positives = 84/196 (42%), Gaps = 62/196 (31%)

Query: 1391 RKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVL 1450
            R  R N TD+D   EDPT+PK KMRR SSCS +PNTPK A C+GD F    TG EA+D L
Sbjct: 339  RLPRGNPTDMDPTLEDPTTPKCKMRRCSSCSPKPNTPKCAMCDGDSFPSACTGGEAKDRL 398

Query: 1451 GELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLK 1510
             E E +K   SSL                         ATAA QA YA IFPSKVC    
Sbjct: 399  REPETEKALSSSL------------------------HATAALQAHYAHIFPSKVC---- 430

Query: 1511 IREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQ 1570
                                              +APA TPSP G       +     A 
Sbjct: 431  ----------------------------------SAPALTPSPVGVLTAPHLAQTLDAAL 456

Query: 1571 AAPPLPPPPESGPGQP 1586
            AAPPLP P     GQP
Sbjct: 457  AAPPLPLPESHAGGQP 472



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 75/233 (32%), Positives = 96/233 (41%), Gaps = 23/233 (9%)

Query: 501 SSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSAS-SPASSSASAATSFSLGSGTFKA 559
           +S++  +P      PG    P AFGK YG   SSS + S ASSS  A TSF LG G F A
Sbjct: 257 ASYSGPKPSTQYGAPGHFAAP-AFGKVYGPTLSSSYTYSDASSSTLAPTSFLLGPGAFNA 315

Query: 560 QESGQGSTAGPLRPPPPGAG--GPATPSKATRFLPM--DPATFRRK-RPESVGGLEPPGP 614
           QESGQGS AGPLRP P G G  G       T   P   DP T + K R  S    +P  P
Sbjct: 316 QESGQGSRAGPLRPLPLGMGAQGRLPRGNPTDMDPTLEDPTTPKCKMRRCSSCSPKPNTP 375

Query: 615 SVI-----AAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAA 669
                   + P +  G   +  +  P  E+         +A     A+  P+   S PA 
Sbjct: 376 KCAMCDGDSFPSACTGGEAKDRLREPETEKALSSSLHATAALQAHYAHIFPSKVCSAPAL 435

Query: 670 TM----VTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVP 718
           T     V        +    +A+ P P        P   AG + +    S+ P
Sbjct: 436 TPSPVGVLTAPHLAQTLDAALAAPPLPL-------PESHAGGQPQRSQDSQYP 481



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 34/46 (73%), Positives = 36/46 (78%), Gaps = 1/46 (2%)

Query: 1  MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAP 46
          MY AHRPLM ASS AS G+ MFVW NVEP SVAVF W+S VPFL P
Sbjct: 1  MYLAHRPLMSASSEASSGVSMFVWRNVEPCSVAVFSWYS-VPFLTP 45



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 76/297 (25%), Positives = 106/297 (35%), Gaps = 55/297 (18%)

Query: 786  PGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYIL--PTLPQ-QLQVAPAP 842
            PG      SG G+ +GP  P+PLG+   G L + G  T +   L  PT P+ +++   + 
Sbjct: 310  PGAFNAQESGQGSRAGPLRPLPLGMGAQGRLPR-GNPTDMDPTLEDPTTPKCKMRRCSSC 368

Query: 843  APAPGTKAAA----PSGPAPTT----SIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPS 894
            +P P T   A     S P+  T      R   P         L ATA       LQ+  +
Sbjct: 369  SPKPNTPKCAMCDGDSFPSACTGGEAKDRLREPETEKALSSSLHATA------ALQAHYA 422

Query: 895  APPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQ 954
               P     +P   P P G            L AP ++     A     L +PP  +P  
Sbjct: 423  HIFPSKVCSAPALTPSPVG-----------VLTAPHLAQTLDAA-----LAAPPLPLPES 466

Query: 955  N-GAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQS---A 1010
            + G QP        P+   T  G           G        LLP+    ++  S   A
Sbjct: 467  HAGGQPQRSQDSQYPLRTWTVCG-----------GSNGGQDGYLLPAVPGESWAVSLLRA 515

Query: 1011 GGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAP 1067
              H +  GT  A   +   + +G       G   LGP G A     L    APLL+P
Sbjct: 516  PVHTMNCGTFRAFHFSENSSCWGYKMECEEG---LGPQGGACG---LRGVHAPLLSP 566


>gi|169171899 PREDICTED: similar to hCG2014367 [Homo sapiens]
          Length = 594

 Score =  221 bits (564), Expect = 3e-57
 Identities = 136/244 (55%), Positives = 151/244 (61%), Gaps = 39/244 (15%)

Query: 172 QSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRA--LVHQRHPNQDNRT 229
           QSLSAL KE+DSSSEKDG SPNK +KDHIR PM+      +        HQ HPNQDNRT
Sbjct: 80  QSLSALRKEQDSSSEKDGCSPNKWDKDHIRWPMSGGHDLQQAAPGPGRAHQGHPNQDNRT 139

Query: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLA 289
           VS++L + WY LGP E QKYHDLAFQ              CNK                 
Sbjct: 140 VSQMLSKRWYTLGPNETQKYHDLAFQE-------------CNKG---------------- 170

Query: 290 GGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGS 349
                + ER +SETGTA APGVSSELLSVAAQTL SSDTK       G    H+  G   
Sbjct: 171 -----SWERRISETGTATAPGVSSELLSVAAQTLQSSDTKE--QLLWGRMAAHS-QGTWL 222

Query: 350 ARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGA 409
           +  +AFSHSGVHSLDG E+D QAL+ELTQ+VSG ASYSGPKPSTQYGAPG FAAP  G  
Sbjct: 223 SLAQAFSHSGVHSLDGREIDRQALRELTQVVSGTASYSGPKPSTQYGAPGHFAAPAFGKV 282

Query: 410 LAAT 413
              T
Sbjct: 283 YGPT 286



 Score =  107 bits (268), Expect = 7e-23
 Identities = 77/196 (39%), Positives = 85/196 (43%), Gaps = 62/196 (31%)

Query: 1391 RKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVL 1450
            R  R N TD+D   EDPT+PK KMRR SSCS +PNTPK A C+GD F F  TG EA+D L
Sbjct: 339  RLPRGNPTDMDPTLEDPTTPKCKMRRCSSCSPKPNTPKCAMCDGDSFPFACTGGEAKDRL 398

Query: 1451 GELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLK 1510
             E E +K   SSL                         ATAA QA YA IFPSKVC    
Sbjct: 399  REPETEKALSSSL------------------------HATAALQAHYAHIFPSKVC---- 430

Query: 1511 IREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQ 1570
                                              +APA TPSP G       +     A 
Sbjct: 431  ----------------------------------SAPALTPSPVGVLTAPHLAQTLDAAL 456

Query: 1571 AAPPLPPPPESGPGQP 1586
            AAPPLP P     GQP
Sbjct: 457  AAPPLPLPESHAGGQP 472



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 44/80 (55%), Positives = 49/80 (61%), Gaps = 2/80 (2%)

Query: 501 SSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSAS-SPASSSASAATSFSLGSGTFKA 559
           +S++  +P      PG    P AFGK YG   SSS + S ASSS  A TSF LG G F A
Sbjct: 257 ASYSGPKPSTQYGAPGHFAAP-AFGKVYGPTLSSSYTYSDASSSTLAPTSFLLGPGAFNA 315

Query: 560 QESGQGSTAGPLRPPPPGAG 579
           QESGQGS AGPLRP P G G
Sbjct: 316 QESGQGSRAGPLRPLPLGMG 335



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 34/46 (73%), Positives = 36/46 (78%), Gaps = 1/46 (2%)

Query: 1  MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAP 46
          MY AHRPLM ASS AS G+ MFVW NVEP SVAVF W+S VPFL P
Sbjct: 1  MYLAHRPLMSASSEASSGVSMFVWRNVEPCSVAVFSWYS-VPFLTP 45



 Score = 31.6 bits (70), Expect = 6.5
 Identities = 76/297 (25%), Positives = 105/297 (35%), Gaps = 55/297 (18%)

Query: 786  PGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYIL--PTLPQ-QLQVAPAP 842
            PG      SG G+ +GP  P+PLG+   G L + G  T +   L  PT P+ +++   + 
Sbjct: 310  PGAFNAQESGQGSRAGPLRPLPLGMGAQGRLPR-GNPTDMDPTLEDPTTPKCKMRRCSSC 368

Query: 843  APAPGTKAAA----PSGPAPTT----SIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPS 894
            +P P T   A     S P   T      R   P         L ATA       LQ+  +
Sbjct: 369  SPKPNTPKCAMCDGDSFPFACTGGEAKDRLREPETEKALSSSLHATA------ALQAHYA 422

Query: 895  APPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQ 954
               P     +P   P P G            L AP ++     A     L +PP  +P  
Sbjct: 423  HIFPSKVCSAPALTPSPVG-----------VLTAPHLAQTLDAA-----LAAPPLPLPES 466

Query: 955  N-GAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQS---A 1010
            + G QP        P+   T  G           G        LLP+    ++  S   A
Sbjct: 467  HAGGQPQRSQDSQYPLRTWTVCG-----------GSNGGQDGYLLPAVPGESWAVSLLRA 515

Query: 1011 GGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAP 1067
              H +  GT  A   +   + +G       G   LGP G A     L    APLL+P
Sbjct: 516  PVHTMNCGTFRAFHFSENSSCWGYKMECEEG---LGPQGGACG---LGGVHAPLLSP 566


>gi|169171130 PREDICTED: hypothetical protein LOC100130600 [Homo
           sapiens]
          Length = 594

 Score =  221 bits (564), Expect = 3e-57
 Identities = 136/244 (55%), Positives = 151/244 (61%), Gaps = 39/244 (15%)

Query: 172 QSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRA--LVHQRHPNQDNRT 229
           QSLSAL KE+DSSSEKDG SPNK +KDHIR PM+      +        HQ HPNQDNRT
Sbjct: 80  QSLSALRKEQDSSSEKDGCSPNKWDKDHIRWPMSGGHDLQQAAPGPGRAHQGHPNQDNRT 139

Query: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLA 289
           VS++L + WY LGP E QKYHDLAFQ              CNK                 
Sbjct: 140 VSQMLSKRWYTLGPNETQKYHDLAFQE-------------CNKG---------------- 170

Query: 290 GGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGS 349
                + ER +SETGTA APGVSSELLSVAAQTL SSDTK       G    H+  G   
Sbjct: 171 -----SWERRISETGTATAPGVSSELLSVAAQTLQSSDTKE--QLLWGRMAAHS-QGTWL 222

Query: 350 ARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGA 409
           +  +AFSHSGVHSLDG E+D QAL+ELTQ+VSG ASYSGPKPSTQYGAPG FAAP  G  
Sbjct: 223 SLAQAFSHSGVHSLDGREIDRQALRELTQVVSGTASYSGPKPSTQYGAPGHFAAPAFGKV 282

Query: 410 LAAT 413
              T
Sbjct: 283 YGPT 286



 Score =  107 bits (268), Expect = 7e-23
 Identities = 77/196 (39%), Positives = 85/196 (43%), Gaps = 62/196 (31%)

Query: 1391 RKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVL 1450
            R  R N TD+D   EDPT+PK KMRR SSCS +PNTPK A C+GD F F  TG EA+D L
Sbjct: 339  RLPRGNPTDMDPTLEDPTTPKCKMRRCSSCSPKPNTPKCAMCDGDSFPFACTGGEAKDRL 398

Query: 1451 GELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLK 1510
             E E +K   SSL                         ATAA QA YA IFPSKVC    
Sbjct: 399  REPETEKALSSSL------------------------HATAALQAHYAHIFPSKVC---- 430

Query: 1511 IREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQ 1570
                                              +APA TPSP G       +     A 
Sbjct: 431  ----------------------------------SAPALTPSPVGVLTAPHLAQTLDAAL 456

Query: 1571 AAPPLPPPPESGPGQP 1586
            AAPPLP P     GQP
Sbjct: 457  AAPPLPLPESHAGGQP 472



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 44/80 (55%), Positives = 49/80 (61%), Gaps = 2/80 (2%)

Query: 501 SSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSAS-SPASSSASAATSFSLGSGTFKA 559
           +S++  +P      PG    P AFGK YG   SSS + S ASSS  A TSF LG G F A
Sbjct: 257 ASYSGPKPSTQYGAPGHFAAP-AFGKVYGPTLSSSYTYSDASSSTLAPTSFLLGPGAFNA 315

Query: 560 QESGQGSTAGPLRPPPPGAG 579
           QESGQGS AGPLRP P G G
Sbjct: 316 QESGQGSRAGPLRPLPLGMG 335



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 34/46 (73%), Positives = 36/46 (78%), Gaps = 1/46 (2%)

Query: 1  MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAP 46
          MY AHRPLM ASS AS G+ MFVW NVEP SVAVF W+S VPFL P
Sbjct: 1  MYLAHRPLMSASSEASSGVSMFVWRNVEPCSVAVFSWYS-VPFLTP 45



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 4/70 (5%)

Query: 786 PGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYIL--PTLPQ-QLQVAPAP 842
           PG      SG G+ +GP  P+PLG+   G L + G  T +   L  PT P+ +++   + 
Sbjct: 310 PGAFNAQESGQGSRAGPLRPLPLGMGAQGRLPR-GNPTDMDPTLEDPTTPKCKMRRCSSC 368

Query: 843 APAPGTKAAA 852
           +P P T   A
Sbjct: 369 SPKPNTPKCA 378


>gi|239509024 PREDICTED: similar to hCG2014367 [Homo sapiens]
          Length = 594

 Score =  221 bits (564), Expect = 3e-57
 Identities = 136/244 (55%), Positives = 151/244 (61%), Gaps = 39/244 (15%)

Query: 172 QSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRA--LVHQRHPNQDNRT 229
           QSLSAL KE+DSSSEKDG SPNK +KDHIR PM+      +        HQ HPNQDNRT
Sbjct: 80  QSLSALRKEQDSSSEKDGCSPNKWDKDHIRWPMSGGHDLQQAAPGPGRAHQGHPNQDNRT 139

Query: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLA 289
           VS++L + WY LGP E QKYHDLAFQ              CNK                 
Sbjct: 140 VSQMLSKRWYTLGPNETQKYHDLAFQE-------------CNKG---------------- 170

Query: 290 GGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGS 349
                + ER +SETGTA APGVSSELLSVAAQTL SSDTK       G    H+  G   
Sbjct: 171 -----SWERRISETGTATAPGVSSELLSVAAQTLQSSDTKE--QLLWGRMAAHS-QGTWL 222

Query: 350 ARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGA 409
           +  +AFSHSGVHSLDG E+D QAL+ELTQ+VSG ASYSGPKPSTQYGAPG FAAP  G  
Sbjct: 223 SLAQAFSHSGVHSLDGREIDRQALRELTQVVSGTASYSGPKPSTQYGAPGHFAAPAFGKV 282

Query: 410 LAAT 413
              T
Sbjct: 283 YGPT 286



 Score =  107 bits (268), Expect = 7e-23
 Identities = 77/196 (39%), Positives = 85/196 (43%), Gaps = 62/196 (31%)

Query: 1391 RKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVL 1450
            R  R N TD+D   EDPT+PK KMRR SSCS +PNTPK A C+GD F F  TG EA+D L
Sbjct: 339  RLPRGNPTDMDPTLEDPTTPKCKMRRCSSCSPKPNTPKCAMCDGDSFPFACTGGEAKDRL 398

Query: 1451 GELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLK 1510
             E E +K   SSL                         ATAA QA YA IFPSKVC    
Sbjct: 399  REPETEKALSSSL------------------------HATAALQAHYAHIFPSKVC---- 430

Query: 1511 IREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQ 1570
                                              +APA TPSP G       +     A 
Sbjct: 431  ----------------------------------SAPALTPSPVGVLTAPHLAQTLDAAL 456

Query: 1571 AAPPLPPPPESGPGQP 1586
            AAPPLP P     GQP
Sbjct: 457  AAPPLPLPESHAGGQP 472



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 44/80 (55%), Positives = 49/80 (61%), Gaps = 2/80 (2%)

Query: 501 SSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSAS-SPASSSASAATSFSLGSGTFKA 559
           +S++  +P      PG    P AFGK YG   SSS + S ASSS  A TSF LG G F A
Sbjct: 257 ASYSGPKPSTQYGAPGHFAAP-AFGKVYGPTLSSSYTYSDASSSTLAPTSFLLGPGAFNA 315

Query: 560 QESGQGSTAGPLRPPPPGAG 579
           QESGQGS AGPLRP P G G
Sbjct: 316 QESGQGSRAGPLRPLPLGMG 335



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 34/46 (73%), Positives = 36/46 (78%), Gaps = 1/46 (2%)

Query: 1  MYSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAP 46
          MY AHRPLM ASS AS G+ MFVW NVEP SVAVF W+S VPFL P
Sbjct: 1  MYLAHRPLMSASSEASSGVSMFVWRNVEPCSVAVFSWYS-VPFLTP 45



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 4/70 (5%)

Query: 786 PGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYIL--PTLPQ-QLQVAPAP 842
           PG      SG G+ +GP  P+PLG+   G L + G  T +   L  PT P+ +++   + 
Sbjct: 310 PGAFNAQESGQGSRAGPLRPLPLGMGAQGRLPR-GNPTDMDPTLEDPTTPKCKMRRCSSC 368

Query: 843 APAPGTKAAA 852
           +P P T   A
Sbjct: 369 SPKPNTPKCA 378


>gi|239753062 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 811

 Score =  211 bits (538), Expect = 3e-54
 Identities = 133/247 (53%), Positives = 150/247 (60%), Gaps = 46/247 (18%)

Query: 172 QSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRA--LVHQRHPNQDNRT 229
           QSLSAL KE+DSSSEKDGRSPNK +KDHI  PM+      +        HQ HPNQDNRT
Sbjct: 297 QSLSALRKEQDSSSEKDGRSPNKWDKDHIWWPMSGSHNLQQAAPGPGRAHQGHPNQDNRT 356

Query: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLA 289
           +S++L E WY LGP E QKY DLAFQ              CNK                 
Sbjct: 357 ISQMLSEQWYTLGPNEMQKY-DLAFQE-------------CNKG---------------- 386

Query: 290 GGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAP---GSSSCGAERLHTVGG 346
                + E S+SE GTA APGVSSELLSVAAQTL SSDTK     G ++  ++       
Sbjct: 387 -----SWEWSISEMGTATAPGVSSELLSVAAQTLQSSDTKEQLLWGRTAAHSQETWL--- 438

Query: 347 PGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGE 406
              +  +AFSHSGVHSLDG E+D QALQELTQ+VSG ASYSGPKPSTQYGAPG FAAP  
Sbjct: 439 ---SLAQAFSHSGVHSLDGREIDRQALQELTQVVSGTASYSGPKPSTQYGAPGHFAAPAF 495

Query: 407 GGALAAT 413
           G     T
Sbjct: 496 GKVYGPT 502



 Score =  104 bits (260), Expect = 6e-22
 Identities = 75/196 (38%), Positives = 84/196 (42%), Gaps = 62/196 (31%)

Query: 1391 RKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVL 1450
            R  R N TD+D   EDPT+P+ KMRR SSCS +PNTPK A C+GD F F  TG EAED L
Sbjct: 555  RLPRGNPTDMDPTLEDPTTPRCKMRRCSSCSPKPNTPKCAMCDGDSFPFACTGGEAEDRL 614

Query: 1451 GELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLK 1510
             E E +K   SSL                         ATAA QA YA IFPSKVC    
Sbjct: 615  REPETEKALSSSL------------------------HATAALQAHYAHIFPSKVC---- 646

Query: 1511 IREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQ 1570
                                              +APA TPSP G       +     A 
Sbjct: 647  ----------------------------------SAPALTPSPVGFLTGPHLAQTLDAAL 672

Query: 1571 AAPPLPPPPESGPGQP 1586
             APPLP P     G+P
Sbjct: 673  VAPPLPLPESHAGGRP 688



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 44/80 (55%), Positives = 49/80 (61%), Gaps = 2/80 (2%)

Query: 501 SSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSAS-SPASSSASAATSFSLGSGTFKA 559
           +S++  +P      PG    P AFGK YG   SSS + S ASSS  A TSF LG G FKA
Sbjct: 473 ASYSGPKPSTQYGAPGHFAAP-AFGKVYGPTLSSSYTYSDASSSTLAPTSFLLGPGAFKA 531

Query: 560 QESGQGSTAGPLRPPPPGAG 579
           QESGQ S AGPLRP P G G
Sbjct: 532 QESGQDSRAGPLRPLPLGMG 551



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 35/68 (51%), Positives = 41/68 (60%), Gaps = 6/68 (8%)

Query: 2   YSAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQP 61
           YSA RP   A S ASRG+ MFVW NVE  SVAVFPW+S +PFL P  P   ++PS+    
Sbjct: 222 YSAPRP---AFSEASRGVSMFVWRNVEGHSVAVFPWYS-IPFLTP--PCSHMRPSKLPVT 275

Query: 62  ASHPVASN 69
              P   N
Sbjct: 276 QWPPTREN 283


>gi|239742769 PREDICTED: hypothetical protein XP_002342619 [Homo
           sapiens]
          Length = 351

 Score =  197 bits (500), Expect = 9e-50
 Identities = 130/260 (50%), Positives = 147/260 (56%), Gaps = 48/260 (18%)

Query: 163 PLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRAL--VHQ 220
           PL     + QSLSAL KE+DSSSEKDGRSPNK +KDHIR PM+      +        HQ
Sbjct: 53  PLLMSVHQAQSLSALRKEQDSSSEKDGRSPNKSDKDHIRWPMSGAHDLQQAAPGPGGAHQ 112

Query: 221 RHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSE 280
            HPNQDNRTVS++L E WY LGP E QKY +LAFQVK AH                    
Sbjct: 113 GHPNQDNRTVSQMLSERWYTLGPNEMQKY-NLAFQVKVAH-------------------- 151

Query: 281 AKPTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAER 340
                  L  G KE + R     G A  PG S            SSDTK       G   
Sbjct: 152 -------LQQGPKEVQLR-----GQAHKPGASRS----------SSDTKE--QLLWGRTA 187

Query: 341 LHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGP 400
            H+  G   +  +AFSHSGVHSLDG E+D QAL+ELTQ+VSG ASYSGPKPSTQ+GAPG 
Sbjct: 188 AHS-QGTWLSLAQAFSHSGVHSLDGREIDRQALRELTQVVSGTASYSGPKPSTQHGAPGH 246

Query: 401 FAAPGEGGALAATGRPPLLP 420
           FAAPGEGG   A   PP +P
Sbjct: 247 FAAPGEGGDPWAALLPPTVP 266



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 21/46 (45%), Positives = 26/46 (56%), Gaps = 9/46 (19%)

Query: 21 MFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPV 66
          MFVW NVE  S AVF W+S +PFL P        P    +P++ PV
Sbjct: 1  MFVWRNVEGHSAAVFSWYS-IPFLTP--------PCSHTRPSNLPV 37


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  176 bits (446), Expect = 2e-43
 Identities = 297/1159 (25%), Positives = 408/1159 (35%), Gaps = 186/1159 (16%)

Query: 509  PLDPEPPGPPDPPVAFGKGYGSAPSSSASSP----ASSSASAATSFSLGSGTFKAQE-SG 563
            P  P    PP      G  + SA +  ASSP       S ++AT+ S G+ T+ A   S 
Sbjct: 737  PSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP 796

Query: 564  QGSTAGPLRPPPP---GAGGPATP---------SKATRFLPMDPATFRRKR--PESVGGL 609
             G +  P    PP   G+ GP TP              FLP +  +F+  +  P +    
Sbjct: 797  LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP 856

Query: 610  EPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAA 669
             PP P     P +      + + LPP    +E     V + P P      PA P   PA 
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPP----KETPTPSVVNLPFPKEGPATPA-PKQAPAL 911

Query: 670  TMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVY 729
            +M ++  +   +TP P   K  P S   + +P   A            P G P   S  +
Sbjct: 912  SMTSSSPKKARATPAP---KGIPASPSPKGAPTPPAATPPS-------PKGGPATPSPKW 961

Query: 730  SDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPG-YGAPAPPAVQFIAQGAPGG 788
            +    AA T P+P    GP                  TP   GAP PPA       +P G
Sbjct: 962  APTPPAA-TPPSPK--GGP-----------------ATPSPKGAPTPPAA---TPPSPKG 998

Query: 789  GTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA-PAPAPAPG 847
            G    S  GA + P    P     P A     G +      P  P+    A P P  AP 
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058

Query: 848  TKAA---APSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVS 904
            T AA   +P G   T S++    P         AAT P+P     +  P+ P PK   + 
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPP--------AATPPSP-----KGGPATPSPKGAPMP 1105

Query: 905  PVQAPP-PGGSAQLLP--GKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPS 961
            P   PP P G     P  G    P A P  S +GG A        PP   P    A PPS
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPP-SPKGGLA------TPPPKGAPTTPAATPPS 1158

Query: 962  KIIQL-TPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTS 1020
                L TP P   P+   P  +P +  G  + P     P++   T     GG A P    
Sbjct: 1159 PKGGLATPPPKGAPT--TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1216

Query: 1021 PASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQL 1080
              ++ A T  S  P   +A       P+ PA   P    G A     G    +P P    
Sbjct: 1217 APTTPAATPPS--PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG----APTPPAAT 1270

Query: 1081 PPACAAPGGPVITAFYSGSPAP---TSSAPLAQPSQAPPSLVYTVATSTTPPAATI-LPK 1136
            PP+     G + T  + G+P P   T  +P   P+ +PP        + TPPAAT   PK
Sbjct: 1271 PPSLK---GGLATPPHKGAPNPAVVTPPSPKGGPATSPPK------GAPTPPAATPPSPK 1321

Query: 1137 GPPA--PATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEA 1194
            G P   P    P P +  P +  G+ T     P + +  P  P   +         S + 
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS-KGGPTTPSSKEGPTPPAATPSHKG 1380

Query: 1195 GASGRPGPAPRQPLEPGPVREPTAPES-ELEGQPTPPAPPPLPETWTPTARSSPPLPPPA 1253
            G +  P    R P  P P  +PT+P    L  +  P  P       TP   S   L PPA
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP---SKGDLTPPA 1437

Query: 1254 EERTSAK-GPETMASK----FPSSSSDWRVPGQGLENRGEPPTP--------PSPAPA-- 1298
                S K  P T A K     PSS  D  +P     +  EPP P        P  APA  
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP 1497

Query: 1299 --------PAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVL 1350
                    PAV P    E  +  ++   P    A    KK      P +           
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA----- 1552

Query: 1351 SEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSP 1410
              V   ++   +P   P+E   +P+ +  A+SP A+  S  K   +  +L   P   TSP
Sbjct: 1553 MTVPSPKKTPAIPT--PKEAPATPSSKE-ASSPPAVTPSTYKGAPSPKEL-LIPPAVTSP 1608

Query: 1411 KRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQR 1470
              K        + P+  K              G       G      V  SSL+ +    
Sbjct: 1609 SPKEAPTPPAVTPPSPEK--------------GPATPAPKGTPTSPPVTPSSLKDS---- 1650

Query: 1471 RALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPG 1530
                          P++ A+   +        SK     K     ++++ A  P E  P 
Sbjct: 1651 --------------PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP-ESTPI 1695

Query: 1531 AEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSG---TAQAAPPLPPPPESGPGQPG 1587
              AP    P T  ++A +P   P    DP++ +   G   T   AP LP   +S     G
Sbjct: 1696 ITAPTRKGPQTKKSSATSPPICP----DPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG 1751

Query: 1588 WEGAPQPSPPPPGPSTAAT 1606
             + +  P  P   P + A+
Sbjct: 1752 KDASHSPKGPLAPPESKAS 1770



 Score =  174 bits (440), Expect = 8e-43
 Identities = 257/994 (25%), Positives = 353/994 (35%), Gaps = 145/994 (14%)

Query: 509  PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTA 568
            P   E P  P P  A       A S ++SSP  + A+ A           A  S +G+  
Sbjct: 894  PFPKEGPATPAPKQA------PALSMTSSSPKKARATPAPK------GIPASPSPKGAPT 941

Query: 569  GPLRPPPPGAGGPATPSKATRFLPM---------DPATFRRKRPESVGGLEPPGPSVIAA 619
             P   PP   GGPATPS      P           PAT   K   +     PP P    A
Sbjct: 942  PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001

Query: 620  PPSGGGNILQTLVLPPNKEEQEGG-----GARVPSAPAPSLAYGAPAA-PLSRPAATMVT 673
             PS  G      V PP+ +          GA  P A  P    G+PAA PL + A T   
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT-- 1059

Query: 674  NVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKK 733
                P ++ P P      P+   A   P  T  +  + G  +  P G+P+  +      K
Sbjct: 1060 ----PAATLPSPKGGPATPSLKGAPTPPAATPPS-PKGGPATPSPKGAPMPPAATPPSPK 1114

Query: 734  SAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAG 793
               AT P       P        P +    L   P  GAP  PA       +P GG    
Sbjct: 1115 GGLATPPHKGAPTTP-----AATPPSPKGGLATPPPKGAPTTPAA---TPPSPKGGLATP 1166

Query: 794  SGAGAGSGPNG--PVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAA 851
               GA + P    P P G L   A     G        P  P+     P+P  AP T AA
Sbjct: 1167 PPKGAPTTPAATPPSPKGGL---ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223

Query: 852  APSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPP 911
             P  P+P   +    P G  T     AAT P+P     +  P+ PPPK     P   PP 
Sbjct: 1224 TP--PSPKGGLATPSPKGAPTTP---AATPPSP-----KGGPATPPPKGAPTPPAATPPS 1273

Query: 912  --GGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPS-KIIQLTP 968
              GG A         P      S +GG      P  SPP   P    A PPS K    TP
Sbjct: 1274 LKGGLATPPHKGAPNPAVVTPPSPKGG------PATSPPKGAPTPPAATPPSPKGSPGTP 1327

Query: 969  VPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGT 1028
             P   P+   P ++P +  G  + P     PSS       S+     P   +P+      
Sbjct: 1328 PPKGAPTP--PAVTPPSPKGTPTLPATT--PSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383

Query: 1029 VTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAP- 1087
            +T   P    A+      P+ PA +   LS  +AP     + G +      L P    P 
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIP--LSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441

Query: 1088 ---GGPVITAFYSGSPAPTSSAPLAQPSQAPPS-----LVYTVATSTTPPAATILPKGPP 1139
                 P  +A   G   P+S      P+  PPS         VATS++P  A   P    
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 1140 APATATPAPTSP--------------FPSATAGSMTY--------SLVAPKAQRPSPK-- 1175
            AP      P+SP               P+AT  S           +L+ P    PSPK  
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561

Query: 1176 ----APQKVKAAIASIPVGSFEA--GASGRPGPAPRQPLEPGPVREPTAPESELEGQPTP 1229
                 P++  A  +S    S  A   ++ +  P+P++ L P  V  P+  E+      TP
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621

Query: 1230 PAPPPLPETWTPTAR-SSPPLPPPAEERT-----------------------SAKGP--- 1262
            P+P   P T  P    +SPP+ P + + +                       + KGP   
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681

Query: 1263 -ETMASKFPSSSSDWRVP-GQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPE 1320
             E + +  P S+     P  +G + +    T P   P P+   G     S+   A   P 
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPV 1741

Query: 1321 RKEAAGT--GKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQ- 1377
            +K+++ T  GK     P       +S  +  L+   FE+   + PE       PSP +  
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK-PESASVSAAPSPPVSL 1800

Query: 1378 SLATSPRAILGSYRKKRKNSTDLD-SAPEDPTSP 1410
             LA SP   L   ++   +S  L   +P  P +P
Sbjct: 1801 PLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834



 Score =  173 bits (439), Expect = 1e-42
 Identities = 281/1137 (24%), Positives = 386/1137 (33%), Gaps = 180/1137 (15%)

Query: 515  PGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPP 574
            P    PP   G      P  + SSP S     A+     S +F+  +    +T  P  P 
Sbjct: 803  PQTKRPPTKKGSAGPDTPIGNLSSPVSPVE--ASFLPENSLSFQGSKDSPATTHSPTPPS 860

Query: 575  P-----PGAGGPATPSKATRFLPMDPAT-------FRRKRPESVGGLEPPGPSVIAAPPS 622
            P     P A  P +P K     P +  T       F ++ P +    + P  S+ ++ P 
Sbjct: 861  PKGAPTPSAVTPLSP-KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK 919

Query: 623  GGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSR-----PAATMVTNVVR 677
                      +P +   +   GA  P A  P    G PA P  +     PAAT  +    
Sbjct: 920  KARATPAPKGIPASPSPK---GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG 976

Query: 678  PVSSTP-----VPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDK 732
            P + +P      P A+ P P  G A  SP    GA T        P GSP          
Sbjct: 977  PATPSPKGAPTPPAATPPSPKGGPATPSPK---GAPTPPAVTPPSPKGSPAATPFPKGAS 1033

Query: 733  KSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTA 792
               AAT P+P     P    + K   T     + +P  G PA P++    +GAP     A
Sbjct: 1034 TPPAATPPSPK--GSPAATPLPKGAPTTPAATLPSP-KGGPATPSL----KGAP--TPPA 1084

Query: 793  GSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAA 852
             +      GP  P P G   P A              P  P+     P    AP T AA 
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPA------------ATPPSPKGGLATPPHKGAPTTPAAT 1132

Query: 853  PSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAP--P 910
            P  P+P   +    P G  T     AAT P+P     +   + PPPK    +P   P  P
Sbjct: 1133 P--PSPKGGLATPPPKGAPTTP---AATPPSP-----KGGLATPPPKGAPTTPAATPPSP 1182

Query: 911  PGGSAQLLP-GKVLVPLAAPSMSVRGGGAGQPLPLVSP-PFSVPVQNGAQPPSKIIQLTP 968
             GG A   P G    P A P  S +GG       L +P P   P    A PPS       
Sbjct: 1183 KGGLATPSPKGAPTTPAATPP-SPKGG-------LATPSPKGAPTTPAATPPS-----PK 1229

Query: 969  VPVSTPSGLVPPLSPATLP-----GPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPAS 1023
              ++TPS    P +PA  P     GP + P K                G   P   +P S
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPK----------------GAPTPPAATPPS 1273

Query: 1024 SQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPA 1083
             + G  T     +      T   P G     P   A   P   P     SP  SP  PP 
Sbjct: 1274 LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP----PSPKGSPGTPPP 1329

Query: 1084 CAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPAT 1143
              AP  P +T     SP  T + P   PS        +     TPPAAT   KG PA   
Sbjct: 1330 KGAPTPPAVT---PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386

Query: 1144 ATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAI----------ASIPVGSFE 1193
             +P      PS   G  T   V P + + +P  P   + A           A  PV   +
Sbjct: 1387 PSPKRGPAIPS-PKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 1194 AGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPA 1253
            A A+  P   P  P   G   +PT P         PPAP  +  + +P  + +P  P P 
Sbjct: 1446 APATSAPKGGPATPSSKG---DPTLPAVTPPSPKEPPAPKQVATSSSP--KKAPATPAPM 1500

Query: 1254 EERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGR 1313
               T      +   + P++ S  R P           TP + AP  A+ P   +  S  +
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560

Query: 1314 A-AGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVL- 1371
              A  TP+   A  + K+    P     T+    +                   P+E+L 
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS-------------------PKELLI 1601

Query: 1372 ----PSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTP 1427
                 SP+ +   T P     S  K         +    P +P       SS    P +P
Sbjct: 1602 PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP-------SSLKDSPTSP 1654

Query: 1428 KSAKCE-GDIFTFDRTGTEAE---DVLGELEYDKVPYSSLRRTLDQRRA--LVMQLFQDH 1481
             S  C+ G        G  A+     L E+     P S+   T   R+            
Sbjct: 1655 ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714

Query: 1482 GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPT 1541
               P   A    +   + + P+ +   L +++   K  +    +  P G     P+ PP 
Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPL---LPVQKDSSKTAKGKDASHSPKG-----PLAPPE 1766

Query: 1542 GTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPP 1598
              A+    TP  A   +   P  +S +  AA   P PP S P  P    +P P+ PP
Sbjct: 1767 SKAS----TPLTAAAFEKVLPKPESASVSAA---PSPPVSLPLAP----SPVPTLPP 1812



 Score =  170 bits (431), Expect = 9e-42
 Identities = 318/1216 (26%), Positives = 414/1216 (34%), Gaps = 247/1216 (20%)

Query: 496  SPVIRSSFTHCRPPLDPEPPGPPDP---PVAFGKGYGSAPSSSASSPASSSASAA---TS 549
            SP  +S+ +    PL PE          P+  GK     P+SS +SP   ++SA+   T 
Sbjct: 570  SPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK-----PASSMTSPLGVNSSASVIKTD 624

Query: 550  FSLGSGT----FKAQESGQGSTAGPLRPPPPGAGGPATP-------SKATRFLPMDPATF 598
               G  +     K+        A PL    P    P T        + A+ FL    +  
Sbjct: 625  SYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA 684

Query: 599  RRKRPESVGGLE--PPGPSV-----IAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAP 651
             +  P   G L   P  P+      +A  P      L TLVL P   +         S P
Sbjct: 685  PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPK---------SVP 735

Query: 652  APSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEM 711
            +PSL          +      T+ + PV+S+P     K  PT     ++   + G  T +
Sbjct: 736  SPSLPPAGTPPGTKKVDGISHTSALAPVASSP-----KECPTEDSGASATASSKGTLTYL 790

Query: 712  GTGSRVPGGSPLGVSLVYSDKKSAAATSPA-PHLVAGPLLGTVGK--------------- 755
                     SPLGVS+    K+       A P    G L   V                 
Sbjct: 791  ADSP-----SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG 845

Query: 756  ---APATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQ 812
               +PAT  +    +P  GAP P AV  ++   P G T         S  N P P     
Sbjct: 846  SKDSPATTHSPTPPSPK-GAPTPSAVTPLS---PKGVTLPPKETPTPSVVNLPFP----- 896

Query: 813  PGALGKAGGITQVQYILPTL------PQQLQVAPAPA--PAPGTKAAAPSGPAPTTSIRF 864
                 K G  T      P L      P++ +  PAP   PA  +   AP+ PA T     
Sbjct: 897  -----KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT----- 946

Query: 865  TLPP----GTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPP--GGSAQLL 918
              PP    G +T     A T P    P  +  P+ P PK     P   PP   GG A   
Sbjct: 947  --PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004

Query: 919  PGKVLVPLAAPSMSVRGGGAGQPLP--LVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSG 976
            P     P A    S +G  A  P P    +PP + P      P +     TP+P   P+ 
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA-----TPLPKGAPT- 1058

Query: 977  LVPPLSPATLPGPTSQPQKVLL---PSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYG 1033
                   ATLP P   P    L   P+    T     GG A P         A T  S  
Sbjct: 1059 ----TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS-- 1112

Query: 1034 PTSSVALGFTSLGPSGPAFVQPLLSAGQA---PLLAPGQVGVSPVPSPQ----LPPACAA 1086
            P   +A       P+ PA   P    G A   P  AP     +P PSP+     PP   A
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKGGLATPPPKGA 1171

Query: 1087 PGGPVIT--AFYSGSPAPTSSAPLAQPSQAPPSLVYTVATS------TTPPAATILPKGP 1138
            P  P  T  +   G   P+       P+  PPS    +AT       TTP A    PKG 
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231

Query: 1139 PAPATATPAPTSPF---PSATAGSMTYSLVAPKAQRPSPKA--PQKVKAAIASIPVGSFE 1193
             A  +   APT+P    PS   G  T     P    P+P A  P  +K  +A+ P     
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPAT----PPPKGAPTPPAATPPSLKGGLATPP----- 1282

Query: 1194 AGASGRPGPAPRQPLEP--GPVREPTAPESELEGQPTPPA---PPPLPETWTPTARSSPP 1248
                G P PA   P  P  GP   P       +G PTPPA   P P     TP  + +P 
Sbjct: 1283 --HKGAPNPAVVTPPSPKGGPATSPP------KGAPTPPAATPPSPKGSPGTPPPKGAPT 1334

Query: 1249 LPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGL---------ENRGEPP-TPPSPAPA 1298
              PPA    S KG  T+ +  PSS      P              ++G P  TPPSP   
Sbjct: 1335 --PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392

Query: 1299 PAV-APGGSSESS-----SGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSE 1352
            PA+ +P G   S      S + A  TP  +E A T  K  + PP +      V  +    
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP----VSLKKAPA 1448

Query: 1353 VDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPT---S 1409
                +     P  + +  LP+ T  S    P        K+   S+    AP  P    +
Sbjct: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP------KQVATSSSPKKAPATPAPMGA 1502

Query: 1410 PKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQ 1469
            P       SS    P TP S +        D     A      L   K P      TL  
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRR--------DPIAPTAT-----LLSKKTP-----ATLAP 1544

Query: 1470 RRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPP 1529
            + AL+          PS + T A                              TP E P 
Sbjct: 1545 KEALIPPAMT----VPSPKKTPAIP----------------------------TPKEAPA 1572

Query: 1530 GAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPL--PPPPESGPGQPG 1587
               +     PP  T +     PSP     P + +S S      PP   PP PE GP  P 
Sbjct: 1573 TPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPA 1632

Query: 1588 WEGAPQPSPPPPGPST 1603
             +G P  + PP  PS+
Sbjct: 1633 PKGTP--TSPPVTPSS 1646



 Score =  162 bits (411), Expect = 2e-39
 Identities = 226/835 (27%), Positives = 301/835 (36%), Gaps = 124/835 (14%)

Query: 508  PPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGST 567
            P   P P G   PP A       +P+++     + +  AAT  S   G   A  S +G+ 
Sbjct: 1023 PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG--PATPSLKGAP 1080

Query: 568  AGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPP----GPSVIAA-PPS 622
              P   PP   GGPATPS   +  PM PA      P   GGL  P     P+  AA PPS
Sbjct: 1081 TPPAATPPSPKGGPATPS--PKGAPMPPAA---TPPSPKGGLATPPHKGAPTTPAATPPS 1135

Query: 623  GGGNILQTLVLPPNKEEQEGGGARVPS------APAPSLAYGAPAAPLSRPAATMVTNVV 676
              G     L  PP K       A  PS       P P  A   PAA    P   + T   
Sbjct: 1136 PKGG----LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT--P 1189

Query: 677  RPVSSTPVPIASKPFPTSGRAEASPN--DTAGART----EMGTGSRVPGGSPLGVSLVYS 730
             P  +   P A+ P P  G A  SP    T  A T    + G  +  P G+P   +    
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249

Query: 731  DKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGT 790
              K   AT P       P        P ++   L   P  GAP P  V      +P GG 
Sbjct: 1250 SPKGGPATPPPKGAPTPP-----AATPPSLKGGLATPPHKGAPNPAVV---TPPSPKGGP 1301

Query: 791  TAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPA-PGTK 849
                  GA + P    P     PG     G         PT P     +P   P  P T 
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGA--------PTPPAVTPPSPKGTPTLPATT 1353

Query: 850  AAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAP 909
             ++  GP   +S     PP  + + K     A TP  P  +  P+ P PK    SP   P
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHK--GGPAMTPPSP--KRGPAIPSPKGDPTSPAVIP 1409

Query: 910  PPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLP-LVSPPFSVPVQNGAQPPSKIIQLTP 968
                         L P  AP+  V   GA  P    ++PP   PV     P +   +  P
Sbjct: 1410 -------------LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456

Query: 969  VPVSTPSGLVPPLSPATLPGPTSQ---PQKVLLPSSTRITYVQSA--GGHALPLGTSPAS 1023
               +TPS    P  PA  P    +   P++V   SS +      A  G   LP    P+S
Sbjct: 1457 ---ATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP-AVIPSS 1512

Query: 1024 SQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPA 1083
             +    T       +A   T L    PA + P     +  L+ P     SP  +P +P  
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAP-----KEALIPPAMTVPSPKKTPAIPTP 1567

Query: 1084 CAAPGGP----------VITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATI 1133
              AP  P          V  + Y G+P+P     L  P+   PS       + TPPA T 
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKEL--LIPPAVTSPS----PKEAPTPPAVT- 1620

Query: 1134 LPKGPPAP--ATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAI-ASIPVG 1190
                PP+P    ATPAP         G+ T   V P + + SP +P  V   + A++P  
Sbjct: 1621 ----PPSPEKGPATPAP--------KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQA 1668

Query: 1191 SFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLP 1250
            S   G   + GP   + +   P     APES     P   AP         ++ +SPP+ 
Sbjct: 1669 S--KGLPAKKGPTALKEVLVAP-----APES----TPIITAPTRKGPQTKKSSATSPPIC 1717

Query: 1251 PPAEERTSAKGPETMASKFP--SSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAP 1303
            P    +  +KGP +  +  P      D     +G +    P  P +P  + A  P
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTP 1772



 Score =  135 bits (340), Expect = 3e-31
 Identities = 241/944 (25%), Positives = 324/944 (34%), Gaps = 184/944 (19%)

Query: 520  PPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAG-PLRPPPPGA 578
            P VA     G +  SS +   S S + ATSFSL   T    +S   +T   PL    P +
Sbjct: 375  PVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVS 434

Query: 579  GGPATPSKATRFLPMDPA---TFRRKRPES-------VGGLEPPGPSVIA----APPSGG 624
                TP   T    +  A   TF      S       +  +EP  P+ +     AP    
Sbjct: 435  SVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPS 494

Query: 625  GNILQTLVLP-----PNKEEQEGGGARV--------PSAPAPSLAYGAPAAPLSRPAATM 671
              +  TL +P     P+ E+ +   + V             P+   GAP +P      T 
Sbjct: 495  TQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTK 554

Query: 672  VTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGG-------SPLG 724
                V P+     P  S  F ++  +   P        +   G  +P G       SPLG
Sbjct: 555  KDPTVLPLVQA-APKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG 613

Query: 725  VSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQG 784
            V+   S  K+ +   P     AGPLL +     + +T  +   P   A         A+G
Sbjct: 614  VNSSASVIKTDSYAGPDS---AGPLLKS-----SLITPTVAAFPLESADPAGVAPTTAKG 665

Query: 785  APGGGTTAG---SGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPA 841
                 TTA     G  + +  N PV           K G +T +  ++PT  +   VAP+
Sbjct: 666  TSTYTTTASPFLEGTVSLAPKNHPV-----------KEGTLTTLP-LVPTASENCPVAPS 713

Query: 842  P----AP------APGTKAAAPSGPAPTTSIRFTLPPGTS-------------------- 871
            P    AP      AP    + PS   P        PPGT                     
Sbjct: 714  PQNTCAPLATLVLAPEIPKSVPSPSLPPAGT----PPGTKKVDGISHTSALAPVASSPKE 769

Query: 872  --TNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAP 929
              T     +ATA + G   L  +  +P P   SVSP    PP       P   +  L++P
Sbjct: 770  CPTEDSGASATASSKGT--LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827

Query: 930  SMSVRG-----------GGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLV 978
               V             G    P    SP  + P   GA  PS +  L+P  V+ P    
Sbjct: 828  VSPVEASFLPENSLSFQGSKDSPATTHSP--TPPSPKGAPTPSAVTPLSPKGVTLPPKET 885

Query: 979  PPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSV 1038
            P  S   LP P   P       +  ++   S          SP  ++A       P S  
Sbjct: 886  PTPSVVNLPFPKEGPATPAPKQAPALSMTSS----------SPKKARATPAPKGIPASPS 935

Query: 1039 ALGFTSLGPSGPAFVQPLLSAGQA---PLLAPGQVGVSPVPSPQLPPACAAP-GGPVITA 1094
              G     P+ PA   P    G A   P  AP     +P PSP+  PA  +P G P   A
Sbjct: 936  PKG----APTPPAATPPSPKGGPATPSPKWAPTPPAATP-PSPKGGPATPSPKGAPTPPA 990

Query: 1095 FYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATP-------- 1146
                SP    + P  + +  PP++  T  +    PAAT  PKG   P  ATP        
Sbjct: 991  ATPPSPKGGPATPSPKGAPTPPAV--TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048

Query: 1147 -------APTSP---FPSATAGSMTYSL----VAPKAQRPSPK-APQKVKAAIASIPVGS 1191
                   APT+P    PS   G  T SL      P A  PSPK  P       A +P  +
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108

Query: 1192 FEAGASGRPGPAPRQPLEPGPVREPTAPESEL-----EGQPTPPA------------PPP 1234
                  G     P +     P   P +P+  L     +G PT PA            PPP
Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP 1168

Query: 1235 LPETWTPTARSSPPLPPPAEERTSAKG-PETMASKFPSSSSDWRVPGQGLENRGEPPTPP 1293
                 TP A  +PP P       S KG P T A+  PS       P      +G P TP 
Sbjct: 1169 KGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP----KGAPTTPA 1222

Query: 1294 SPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPP 1337
            +  P+P     G   + S + A  TP     +  G      PPP
Sbjct: 1223 ATPPSPK----GGLATPSPKGAPTTPAATPPSPKGG--PATPPP 1260



 Score =  107 bits (266), Expect = 1e-22
 Identities = 252/1020 (24%), Positives = 342/1020 (33%), Gaps = 242/1020 (23%)

Query: 512  PEPPGPPDPP--------------VAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTF 557
            P P G P PP               +   G  S P ++ ++  + ++      ++ S   
Sbjct: 197  PNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLI 256

Query: 558  KAQESGQGSTAGPLRPP---------------PPGAGGPATPSKATRFLPMDPATFRRKR 602
              Q  G  S  GP+ PP                    GP TP      L    A   +  
Sbjct: 257  SPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSS 316

Query: 603  PESVGGLEPPGPSVIAAP----------PSGGGNILQTLVLPPNKEEQEGGGARVPSAP- 651
              SV  L   GPS ++ P           +G     Q  V+PP     E   A V + P 
Sbjct: 317  FGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPV 376

Query: 652  -APSLAYG---------APAAPL-----------------SRPAATMVTNVV--RPVSS- 681
             APS+  G         +P+  L                 S P AT    +V   PVSS 
Sbjct: 377  VAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSV 436

Query: 682  --TPV------------------------PIASKPF----PTSGRA-EASPNDTAGARTE 710
              TP+                        P++S P     PTS  A   +P       T+
Sbjct: 437  GTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQ 496

Query: 711  MGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTP-- 768
            + T  R+P   PL       D K+     P+  LV  P    +   PA+    L G P  
Sbjct: 497  VATTLRIPVSPPLPDP---EDLKNL----PSSVLVKFPTQKDLQTVPAS----LEGAPFS 545

Query: 769  ----GYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGP------------------- 805
                G      P V  + Q AP    +  S + +   P  P                   
Sbjct: 546  PAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPA 605

Query: 806  ----VPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTS 861
                 PLG+    ++ K           P L   L + P  A  P  ++A P+G APTT+
Sbjct: 606  SSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSL-ITPTVAAFP-LESADPAGVAPTTA 663

Query: 862  IRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPP----------------PKAQSVSP 905
                   GTS        T  T   P L+   S  P                P A    P
Sbjct: 664  ------KGTS--------TYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCP 709

Query: 906  VQAPPPGGSAQLLPGKVLVP-----LAAPSMSVRGGGAGQP-----------LPLVSPPF 949
            V AP P  +   L   VL P     + +PS+   G   G              P+ S P 
Sbjct: 710  V-APSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK 768

Query: 950  SVPVQ-NGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQ----PQKVLLPSSTRI 1004
              P + +GA   +           +PS L   +SP T   PT +    P   +   S+ +
Sbjct: 769  ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPV 828

Query: 1005 TYVQSAGGHALPLGT--------SPASSQAGTVTS--YGPTSSVALGFTSLGPSGPAFVQ 1054
            + V+++    LP  +        SPA++ + T  S    PT S     +  G + P    
Sbjct: 829  SPVEAS---FLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKET 885

Query: 1055 PLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPA-PTSSAPLAQPSQ 1113
            P  S    P    G    +P  +P L    ++P     T    G PA P+       P+ 
Sbjct: 886  PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA 945

Query: 1114 APPSLVYTVAT-----STTPPAAT-ILPKGPPAPATATPAPTSPF---PSATAGSMTYSL 1164
             PPS     AT     + TPPAAT   PKG PA  +   APT P    PS   G  T S 
Sbjct: 946  TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS- 1004

Query: 1165 VAPK-AQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQP-----LEPGPVREPTA 1218
              PK A  P    P   K + A+ P   F  GAS  P   P  P       P P   PT 
Sbjct: 1005 --PKGAPTPPAVTPPSPKGSPAATP---FPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059

Query: 1219 PESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKG-PETMASKFPSSSSDWR 1277
            P + L      PA P L    TP A ++PP P       S KG P   A+  PS      
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPA-ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA 1118

Query: 1278 VPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPP 1337
             P     ++G P TP +  P+P     G   +   + A  TP     +  G      PPP
Sbjct: 1119 TP----PHKGAPTTPAATPPSPK----GGLATPPPKGAPTTPAATPPSPKGG--LATPPP 1168



 Score =  103 bits (257), Expect = 1e-21
 Identities = 267/1155 (23%), Positives = 386/1155 (33%), Gaps = 231/1155 (20%)

Query: 508  PPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPAS---SSASAATSFSLGSGTFKAQESGQ 564
            PP  P P   P         + S PS+ AS+P       +S+ T+  LG+   +A     
Sbjct: 47   PPCSPAPQQCPLSAANQASPFPS-PSTIASTPLEVPFPQSSSGTALPLGTAP-EAPTFLP 104

Query: 565  GSTAGPLRPPPPGAGGP-------ATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVI 617
                 P+ P       P        TPS +       P       P SV       P+++
Sbjct: 105  NLIGPPISPAALALASPMIAPTLKGTPSSSA------PLALVALAPHSVQKSSAFPPNLL 158

Query: 618  AAPPS----GGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVT 673
             +PPS      G+++ TL  P    E +    +VPS   P+   G P+ P     +T+  
Sbjct: 159  TSPPSVAVAESGSVI-TLSAPIAPSEPKTNLNKVPSEVVPN-PKGTPSPPCI--VSTVPY 214

Query: 674  NVVRPVSSTPVPIASKP--FPTSGRAEASPN--DTAGAR---TEMGTGS---RVPGGSPL 723
            + V P++S    +AS P   PT+  A ASP   DT  +    +    GS   + P   P 
Sbjct: 215  HCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPA 274

Query: 724  GVSL-------VYSDKKSAAATSPAPHLVA-GPLLGTVGKAPATVTNLLVGTPGYGAPAP 775
             +SL       V S +K+A   +P    ++ G  L  + ++      LL G  G  A + 
Sbjct: 275  ALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLL-GQTGPSALSD 333

Query: 776  PAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQ 835
            P V+ I+      G +  S                                 ++P LP +
Sbjct: 334  PTVKTISVDHSSTGASYPSQRS------------------------------VIPPLPSR 363

Query: 836  LQVAPAPAPA-PGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPS 894
             +V PA   A P    +   GP+  +SI  T  P  S N     + +PT  + +  S   
Sbjct: 364  NEVVPATVAAFPVVAPSVDKGPSTISSI--TCSPSGSLNVATSFSLSPTTSLILKSS--- 418

Query: 895  APPPKAQSVSPVQAPPPGGSAQLLPGKVLVPL---AAPSMSVRGGGAGQPLPLVSPPFSV 951
               P A    P+ A  P  S    P  V  P    AAP+ +       +    VSPP S 
Sbjct: 419  ---PNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTF------EVATCVSPPMSS 469

Query: 952  -PVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVL-LPSSTRITYVQS 1009
             P+ N        + + PV    PS  V       +  P   P+ +  LPSS  + +   
Sbjct: 470  GPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQ 529

Query: 1010 AGGHALPL---GTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                 +P    G   + +QAG  T   PT                 V PL+ A  AP  +
Sbjct: 530  KDLQTVPASLEGAPFSPAQAGLTTKKDPT-----------------VLPLVQA--APKNS 570

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     S  P   L P        +      G PA + ++PL   S A  S++ T + + 
Sbjct: 571  PSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSA--SVIKTDSYAG 628

Query: 1127 TPPAATILPKGPPAPATA-----TPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVK 1181
               A  +L      P  A     +  P    P+   G+ TY+  A      SP     V 
Sbjct: 629  PDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTA------SPFLEGTVS 682

Query: 1182 AAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTP 1241
             A  + PV         + G     PL                                P
Sbjct: 683  LAPKNHPV---------KEGTLTTLPL-------------------------------VP 702

Query: 1242 TARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSP---APA 1298
            TA  + P+ P  +   +      +A + P S     VP   L   G PP        +  
Sbjct: 703  TASENCPVAPSPQNTCAPLATLVLAPEIPKS-----VPSPSLPPAGTPPGTKKVDGISHT 757

Query: 1299 PAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEER 1358
             A+AP  SS                + GT   +   P PL  +      R          
Sbjct: 758  SALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR---------- 807

Query: 1359 FAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKR----KNSTDLDSAPEDPTSPKRKM 1414
                P  +     P   + +L++    +  S+  +     + S D  +    PT P  K 
Sbjct: 808  ----PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863

Query: 1415 RRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALV 1474
                S  + P +PK         T     T    V+      + P +   +   Q  AL 
Sbjct: 864  APTPSAVT-PLSPKGV-------TLPPKETPTPSVVNLPFPKEGPATPAPK---QAPALS 912

Query: 1475 MQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAP 1534
            M           A+AT A +   A   P                  AATP     G   P
Sbjct: 913  MTSSSPK----KARATPAPKGIPASPSPKGA-----------PTPPAATPPSPKGGPATP 957

Query: 1535 LPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQP 1594
             P   PT  AA P   PSP GGP   SP    G        PP P+ GP  P  +GAP P
Sbjct: 958  SPKWAPTPPAATP---PSPKGGPATPSP---KGAPTPPAATPPSPKGGPATPSPKGAPTP 1011

Query: 1595 ---SPPPPGPSTAAT 1606
               +PP P  S AAT
Sbjct: 1012 PAVTPPSPKGSPAAT 1026



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 159/621 (25%), Positives = 229/621 (36%), Gaps = 119/621 (19%)

Query: 805  PVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAP-----------APAPAPGTKAAAP 853
            P+   +    ALG+ G         PTLP     AP           +P P+P T A+ P
Sbjct: 27   PMSSALSVTAALGQPG---------PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTP 77

Query: 854  -SGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPG 912
               P P +S    LP GT       A  APT  +P L   P +P   A + SP+ AP   
Sbjct: 78   LEVPFPQSSSGTALPLGT-------APEAPT-FLPNLIGPPISPAALALA-SPMIAPTLK 128

Query: 913  GSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNG-----------AQPPS 961
            G+        LV LA    SV+   A  P  L SPP     ++G           ++P +
Sbjct: 129  GTPSSSAPLALVALA--PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKT 186

Query: 962  KI----IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVL------LPSSTRITYVQSAG 1011
             +     ++ P P  TPS   PP   +T+P     P   +      LP +T  T +  A 
Sbjct: 187  NLNKVPSEVVPNPKGTPS---PPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIAS 243

Query: 1012 GHALPLGTSP---ASSQAGTVTSYGPTS---SVALGFTSL----------GPSGPAFVQP 1055
                    S    +    G+++  GP S   +++L   SL          GP+ P     
Sbjct: 244  PQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPI 303

Query: 1056 LLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAP 1115
             L +  AP L     G   +     P A + P    I+  +S + A   S     P    
Sbjct: 304  SLGSHLAP-LHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPS 362

Query: 1116 PSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSM--TYSLV---APKAQ 1170
             + V     +  P  A  + KGP   ++ T +P+     AT+ S+  T SL+   +P A 
Sbjct: 363  RNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNAT 422

Query: 1171 RPSPKAPQKVKAA-------------IASIPVGSFEAGASGRPGPAPRQPLEPGPVR--E 1215
               P   Q   ++             IA+ P  +FE      P      P+  GP+   E
Sbjct: 423  YHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSP------PMSSGPISNIE 476

Query: 1216 PTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSD 1275
            PT+P + L   P  P  P      T     SPPLP P + +     P ++  KFP+    
Sbjct: 477  PTSP-AALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNL---PSSVLVKFPTQKDL 532

Query: 1276 WRVPGQ-----------GLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEA 1324
              VP             GL  + +P   P    AP  +P   S SSS     + P   EA
Sbjct: 533  QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSS----PEIPLSPEA 588

Query: 1325 AGTGKKVKVRPPPLKKTFDSV 1345
                KK    P P+ K   S+
Sbjct: 589  T-LAKKSLGEPLPIGKPASSM 608



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 145/590 (24%), Positives = 199/590 (33%), Gaps = 152/590 (25%)

Query: 509  PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTA 568
            P  P P G P PP          P+  A++P+S       S   G     A  S +G   
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG--- 1380

Query: 569  GPLRPPPPGAGGPATPSK------------ATRFLPMDPATFRRKRPESVGGLEPPGPSV 616
            GP   PP    GPA PS             + +  P  P T       S G L PP  + 
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP 1440

Query: 617  IA--------------APPSGGGNILQTLVLPPNKEEQ--------EGGGARVPSAPAP- 653
            ++              A PS  G+     V PP+ +E              + P+ PAP 
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500

Query: 654  ----------SLAYGAPAAPLSR-----PAATMVTN-----------VVRPVSSTPVPIA 687
                      S     PA P SR     P AT+++            ++ P  + P P  
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560

Query: 688  SKPFPTSGRAEASPNDTAGARTEMGTGSRVPGG-SPLGVSLVYSDKKSAAATSPAPHLVA 746
            +   PT   A A+P+    +     T S   G  SP  + +  +    +   +P P  V 
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620

Query: 747  GPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPV 806
             P   +  K PAT      GTP     +PP      + +P    +     GA       V
Sbjct: 1621 PP---SPEKGPATPAPK--GTP----TSPPVTPSSLKDSPTSPASVTCKMGA------TV 1665

Query: 807  PLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTL 866
            P      G   K G         PT  +++ VAPAP   P   A    GP  T     T 
Sbjct: 1666 PQA--SKGLPAKKG---------PTALKEVLVAPAPESTPIITAPTRKGPQ-TKKSSATS 1713

Query: 867  PP----GTSTNGKV--LAATAPTPGIPILQSV---------------PSAPP-------- 897
            PP     ++ NG    L+  AP P +P+ +                 P APP        
Sbjct: 1714 PPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPL 1773

Query: 898  ---------PKAQSVSPVQAPPPGGSAQLLPGKV--LVP------------LAAPSMSVR 934
                     PK +S S   AP P  S  L P  V  L P            L +PS  + 
Sbjct: 1774 TAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833

Query: 935  GGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQL-TP----VPVSTPSGLVP 979
                 + LPL+ P    P+  G    S ++ + TP    +PV TPS   P
Sbjct: 1834 PADEDELLPLIPPE---PISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 193/816 (23%), Positives = 279/816 (34%), Gaps = 174/816 (21%)

Query: 907  QAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQL 966
            + P P     +LP    + + A          GQP P + PP S   Q    P S   Q 
Sbjct: 15   ELPQPQAETAVLPMSSALSVTA--------ALGQPGPTLPPPCSPAPQQC--PLSAANQA 64

Query: 967  TPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQA 1026
            +P P           SP+T+    S P +V  P        QS+ G ALPLGT+P +   
Sbjct: 65   SPFP-----------SPSTI---ASTPLEVPFP--------QSSSGTALPLGTAPEA--- 99

Query: 1027 GTVTSYGPTSSVALGFTSLGPSGPAFVQPLLS-------AGQAPL----LAPGQVGVSPV 1075
                   PT    L    + P+  A   P+++       +  APL    LAP  V  S  
Sbjct: 100  -------PTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSA 152

Query: 1076 PSPQL---PPACA-APGGPVITAFYSGSPA---------PTSSAPLAQPSQAPPSLVYTV 1122
              P L   PP+ A A  G VIT     +P+         P+   P  + + +PP +V TV
Sbjct: 153  FPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTV 212

Query: 1123 ATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRP---SPKAPQK 1179
                  P A+I       P T TP  T    S      T S V    Q P   S K P  
Sbjct: 213  PYHCVTPMASIQSGVASLPQT-TPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271

Query: 1180 VKAAIA----SIPVGSFEAGASGRPGPAPRQPLEPG----PVREPTAPESELEGQPTPPA 1231
              AA++    S+PV +     +G P   P  P+  G    P+ + +    +L GQ  P A
Sbjct: 272  PPAALSLSTQSLPVVTSSQKTAG-PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSA 330

Query: 1232 -PPPLPETWT----------PTARS-SPPLPP------------PAEERTSAKGPETMAS 1267
               P  +T +          P+ RS  PPLP             P    +  KGP T++S
Sbjct: 331  LSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISS 390

Query: 1268 KFPSSSSDWRV-------PGQGLENRGEP------------------------PTPPSPA 1296
               S S    V       P   L  +  P                          P + A
Sbjct: 391  ITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIA 450

Query: 1297 PAPA----VAPGGSSESSSGRAAGDTP--------------ERKEAAGTGKKVKVRPP-P 1337
             AP     VA   S   SSG  +   P              E      T  ++ V PP P
Sbjct: 451  AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLP 510

Query: 1338 LKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLAT-SPRAILGSYRKKRKN 1396
              +   ++ + VL +   ++    +P    E    SP    L T     +L   +   KN
Sbjct: 511  DPEDLKNLPSSVLVKFPTQKDLQTVPA-SLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKN 569

Query: 1397 STDL---DSAPEDPTSPKRKMRRRSSCSSEP-NTPKSAKCEGDIFTFDRTGTEAEDVLGE 1452
            S       S+PE P SP+  + ++S     P   P S+           +  + +   G 
Sbjct: 570  SPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGP 629

Query: 1453 LEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFP-SAQATAAFQARYADIFPSKVCLQLKI 1511
                 +  SSL        A  ++     G  P +A+ T+ +    +      V L  K 
Sbjct: 630  DSAGPLLKSSL--ITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN 687

Query: 1512 REVRQKIMQ----AATPTEQPPGAEAPLPVPPPTGT--------AAAPAPTPSPAGGPDP 1559
              V++  +       T +E  P A +P     P  T         + P+P+  PAG P  
Sbjct: 688  HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPG 747

Query: 1560 TSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPS 1595
            T          A  P+   P+  P +     A   S
Sbjct: 748  TKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 77/300 (25%), Positives = 113/300 (37%), Gaps = 38/300 (12%)

Query: 980  PLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQ----AGTVTSYGPT 1035
            P +   LP P ++   + + S+  +T      G  LP   SPA  Q    A    S  P+
Sbjct: 10   PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69

Query: 1036 SSVALGFTSLGP---SGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVI 1092
             S         P   S      PL +A +AP   P  +G      P + PA  A   P+I
Sbjct: 70   PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIG------PPISPAALALASPMI 123

Query: 1093 TAFYSGSPAPTSSAPLAQPSQAPPSLVYTVA----TSTTPPAATILPKGPPAPATATPAP 1148
                 G+  P+SSAPLA  + AP S+  + A      T+PP+  +   G     +A  AP
Sbjct: 124  APTLKGT--PSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181

Query: 1149 TSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPL 1208
            +   P      +   +V      PSP             P+ S ++G +  P   P   L
Sbjct: 182  SE--PKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTL 239

Query: 1209 --EPGPVREPT------APES----ELEGQPTPPAPPPLPETWTPTARSS-----PPLPP 1251
                  V++ T      +P++     L+G  +PPA   L     P   SS     P  PP
Sbjct: 240  AIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPP 299



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 128/562 (22%), Positives = 183/562 (32%), Gaps = 81/562 (14%)

Query: 383  PASYSGPK-PSTQYGAPGPFAAPGEGGALAATG----RPPLLPTRASRSQRAASEDMTSD 437
            P+S  GP  PS++ G   P A P   G  A T     R P +P+        A   ++  
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413

Query: 438  EERMVICEEEGDDDVIADDGF--GTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVF 495
            +        EG       D      T + LK K   T +  G  +    +G+      V 
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLK-KAPATSAPKGGPATPSSKGDPTLPA-VT 1471

Query: 496  SPV---------IRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASA 546
             P          + +S +  + P  P P G P  P        S+P    ++P+S     
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP----SSPKEVPATPSSRRDPI 1527

Query: 547  ATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESV 606
            A + +L S    A  + + +   P    P     PA P+         PAT     P S 
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA-----PAT-----PSSK 1577

Query: 607  GGLEPPG--PSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPL 664
                PP   PS     PS    ++   V  P+ +E     A  P +P    A  AP    
Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637

Query: 665  SRPAAT---MVTNVVRPVSST-----PVPIASKPFPTSGRAEA--------SPNDTAGAR 708
            + P  T   +  +   P S T      VP ASK  P      A        +P  T    
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697

Query: 709  TEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTP 768
                 G +    S     +         +  P   +   PLL     +  T         
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757

Query: 769  GYGAPAPP---AVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQV 825
              G  APP   A   +   A          A   + P+ PV L  L P  +         
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP-LAPSPV--------- 1807

Query: 826  QYILPTLPQQLQVAPAPAPAPGTKAAAPS---GPAPTTSIRFTLPPGTSTNG---KVLAA 879
                PTLP + Q  P+   +PG    +PS    PA    +   +PP   + G   + +  
Sbjct: 1808 ----PTLPPKQQFLPS---SPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLV 1860

Query: 880  TAPTP---GIPILQSVPSAPPP 898
              PTP   GIP+    PSA  P
Sbjct: 1861 NMPTPKSAGIPV--PTPSAKQP 1880



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 118/532 (22%), Positives = 178/532 (33%), Gaps = 110/532 (20%)

Query: 1158 GSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPT 1217
            G  T ++ A + + P P+A   V    +++ V      A G+PGP    P  P P + P 
Sbjct: 3    GEATETVPATEQELPQPQAETAVLPMSSALSV----TAALGQPGPTLPPPCSPAPQQCPL 58

Query: 1218 APESELEGQPTP------PAPPPLPETWTPTARS---------------SPPLPPPAEER 1256
            +  ++    P+P      P   P P++ + TA                  PP+ P A   
Sbjct: 59   SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALAL 118

Query: 1257 TSAKGPETMASKFPSSSSDWRV----PGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSG 1312
             S     T+    PSSS+   +    P    ++   PP   +  P+ AVA  GS  + S 
Sbjct: 119  ASPMIAPTLKGT-PSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA 177

Query: 1313 RAAGDTPE---RKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEE 1369
              A   P+    K  +      K  P P         + V      +   A LP+  P  
Sbjct: 178  PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237

Query: 1370 VL--PSP-----TLQSLATSPR-----AILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRR 1417
             L   SP     T+ S+  SP+     ++ G        S    S P   +S K      
Sbjct: 238  TLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQK------ 291

Query: 1418 SSCSSEPNTPKSAKCE-------------GDIFTFDRTGTEAEDVLGELEYDKVPYSSLR 1464
               ++ PNTP                   G +    +TG  A      ++   V +SS  
Sbjct: 292  ---TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSD-PTVKTISVDHSSTG 347

Query: 1465 RTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKV----CLQLKIREVRQKIMQ 1520
             +   +R+++  L   +   P+  A     A   D  PS +    C       V      
Sbjct: 348  ASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL 407

Query: 1521 AATPT---EQPPGA----------------EAPLPVPPPTGTAAAPAPT--------PSP 1553
            + T +   +  P A                  PL V  P   AAAP  T        P  
Sbjct: 408  SPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPM 467

Query: 1554 AGGP----DPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGP 1601
            + GP    +PTSP++       AP  P  P +   Q         SPP P P
Sbjct: 468  SSGPISNIEPTSPAA----LVMAPVAPKEPST---QVATTLRIPVSPPLPDP 512



 Score = 38.1 bits (87), Expect = 0.069
 Identities = 39/138 (28%), Positives = 50/138 (36%), Gaps = 20/138 (14%)

Query: 47   SQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGG--TGSADPERPPGATCPE 104
            S P  +  PS    PA+ P+       PA +       P GG  T S      P A  P 
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLP----SPKGGPATPSLKGAPTPPAATPP 1088

Query: 105  SP--GPGPPHPLGVVESGKGPPPTTEEEASGPP--GEPRLDSETESDHDDAFLSIMSPEI 160
            SP  GP  P P G        PP+ +   + PP  G P   + T            SP+ 
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP----------SPKG 1138

Query: 161  QLPLPPGKRRTQSLSALP 178
             L  PP K    + +A P
Sbjct: 1139 GLATPPPKGAPTTPAATP 1156



 Score = 38.1 bits (87), Expect = 0.069
 Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 20/111 (18%)

Query: 46   PSQPDPSVQPSEAQQPASHP------VASNQSKEPAESAAVAHERPPGGTGSADPE---R 96
            P+ P P   P+    PA+ P      +A+   K     A V    P GG  ++ P+    
Sbjct: 1255 PATPPPKGAPTP---PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311

Query: 97   PPGATCPESPG-PGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETES 146
            PP AT P   G PG P P G        PP+       P G P L + T S
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPS-------PKGTPTLPATTPS 1355



 Score = 37.7 bits (86), Expect = 0.090
 Identities = 31/103 (30%), Positives = 36/103 (34%), Gaps = 30/103 (29%)

Query: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPT----PSPAGGP--------------DPTSPSSD 1565
            P   PP  +  L  PP  G   AP P     PSP GGP               P SP   
Sbjct: 1267 PAATPPSLKGGLATPPHKG---APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323

Query: 1566 SGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608
             GT        PPP+  P  P     P P   P  P+T  + +
Sbjct: 1324 PGT--------PPPKGAPTPPA-VTPPSPKGTPTLPATTPSSK 1357



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 35/140 (25%), Positives = 50/140 (35%), Gaps = 10/140 (7%)

Query: 3   SAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLA--PSQPDPSVQPSEAQQ 60
           + H P  P+   A     +   T + P+ V + P  +  P +   P   +    P+  Q 
Sbjct: 852 TTHSPTPPSPKGAPTPSAV---TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA 908

Query: 61  PASHPVASNQSK---EPAESAAVAHERPPGG--TGSADPERPPGATCPESPGPGPPHPLG 115
           PA    +S+  K    PA     A   P G     +A P  P G     SP   P  P  
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968

Query: 116 VVESGKGPPPTTEEEASGPP 135
              S KG P T   + +  P
Sbjct: 969 TPPSPKGGPATPSPKGAPTP 988



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 51/188 (27%), Positives = 67/188 (35%), Gaps = 26/188 (13%)

Query: 10   PASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQP----SEAQQPASHP 65
            PA+ A  +   + + T+  P+     P     P   P+ P P   P    +    P   P
Sbjct: 900  PATPAPKQAPALSM-TSSSPKKARATP----APKGIPASPSPKGAPTPPAATPPSPKGGP 954

Query: 66   VASNQSKEPAESAAVAHERPPGGTGSADPE---RPPGATCPESP--GPGPPHPLG----- 115
               +    P   AA     P GG  +  P+    PP AT P SP  GP  P P G     
Sbjct: 955  ATPSPKWAPTPPAATP-PSPKGGPATPSPKGAPTPPAAT-PPSPKGGPATPSPKGAPTPP 1012

Query: 116  --VVESGKGPPPTT--EEEASGPP-GEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRR 170
                 S KG P  T   + AS PP   P     + +       +  +P   LP P G   
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA 1072

Query: 171  TQSLSALP 178
            T SL   P
Sbjct: 1073 TPSLKGAP 1080



 Score = 34.7 bits (78), Expect = 0.76
 Identities = 25/92 (27%), Positives = 29/92 (31%), Gaps = 4/92 (4%)

Query: 49   PDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGP 108
            P P   P+        P     +  P  +       PP   G      P GA  P +P  
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA--PTTPAA 1223

Query: 109  GPPHPLG--VVESGKGPPPTTEEEASGPPGEP 138
             PP P G     S KG P T       P G P
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 32/123 (26%), Positives = 41/123 (33%), Gaps = 12/123 (9%)

Query: 25   TNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHER 84
            T   P+     P H   P   P+   PS +   A  P      +  +  P+    +A   
Sbjct: 1109 TPPSPKGGLATPPHKGAP-TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167

Query: 85   PPGG--TGSADPERPPGATC-------PESPGPGPPHPLG--VVESGKGPPPTTEEEASG 133
            P G   T +A P  P G          P +P   PP P G     S KG P T       
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227

Query: 134  PPG 136
            P G
Sbjct: 1228 PKG 1230



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 41/191 (21%), Positives = 62/191 (32%), Gaps = 40/191 (20%)

Query: 7    PLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQP--------------DPS 52
            P +PA++ +S+G      +   P   A  P H   P + P  P               P+
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406

Query: 53   VQPSEAQQPASHPVASNQSKEPAES-------------AAVAHERPPGGTGSADPERPPG 99
            V P   ++  + PV    +  P++               A A   P GG  +   +  P 
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP- 1465

Query: 100  ATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPE 159
             T P    P P  P    +      P        P G P L +   S          SP+
Sbjct: 1466 -TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS----------SPK 1514

Query: 160  IQLPLPPGKRR 170
             ++P  P  RR
Sbjct: 1515 -EVPATPSSRR 1524



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 65/297 (21%), Positives = 96/297 (32%), Gaps = 41/297 (13%)

Query: 509  PLDPEPPGPP-DPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGST 567
            P  P P G P  PPV       S+   S +SPAS +     +    S    A++      
Sbjct: 1628 PATPAPKGTPTSPPVT-----PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALK 1682

Query: 568  AGPLRPPP--------PGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAA 619
               + P P        P   GP T   +    P+ P       P +  G + P  +V  A
Sbjct: 1683 EVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD------PSAKNGSKGPLSTVAPA 1736

Query: 620  PPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPV 679
            P           +LP  K+  +    +  ++ +P      P +  S P        V P 
Sbjct: 1737 P-----------LLPVQKDSSKTAKGK-DASHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784

Query: 680  SSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATS 739
              +    A+   P S     SP  T   + +    S        G+ L    K  A A  
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP-------GLVLESPSKPLAPADE 1837

Query: 740  PA--PHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGS 794
                P +   P+ G V      V      + G   P P A Q + +   G GT + S
Sbjct: 1838 DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1894



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 1/67 (1%)

Query: 1540 PTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPP 1599
            P      P P    A  P  ++ S  +   Q  P LPPP    P Q     A Q S P P
Sbjct: 10   PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQAS-PFP 68

Query: 1600 GPSTAAT 1606
             PST A+
Sbjct: 69   SPSTIAS 75



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 39/150 (26%), Positives = 55/150 (36%), Gaps = 15/150 (10%)

Query: 49   PDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPG--ATCPESP 106
            P+P+V    +  P   P  S     P   AA     P G  G+  P+  P   A  P SP
Sbjct: 1287 PNPAVVTPPS--PKGGPATSPPKGAPTPPAATPPS-PKGSPGTPPPKGAPTPPAVTPPSP 1343

Query: 107  GPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPP 166
               P  P     S  GP   + +E   PP      + T S      ++  SP+    +P 
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPP------AATPSHKGGPAMTPPSPKRGPAIPS 1397

Query: 167  GKRRTQSLSALPKERDSSSEKDGRSPNKRE 196
             K    S + +P     S +K   +P  RE
Sbjct: 1398 PKGDPTSPAVIP----LSPKKAPATPVTRE 1423



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 24/94 (25%), Positives = 33/94 (35%), Gaps = 4/94 (4%)

Query: 46   PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPG--ATCP 103
            PS       P+         +A+   K    + A     P GG  +  P+  P   A  P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 104  ESP--GPGPPHPLGVVESGKGPPPTTEEEASGPP 135
             SP  GP  P P G        PP+ +   + PP
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282



 Score = 31.6 bits (70), Expect = 6.5
 Identities = 24/96 (25%), Positives = 33/96 (34%), Gaps = 6/96 (6%)

Query: 42   PFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGG--TGSADPERPPG 99
            P   P  P   +     +   + P A+     P+    +A   P G   T +A P  P G
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAAT----PPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 100  ATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPP 135
                 SP   P  P     S KG P T   + +  P
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTP 1266



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 44/180 (24%), Positives = 62/180 (34%), Gaps = 52/180 (28%)

Query: 40  LVPFLAPSQPDPSVQPSE-----------AQQPASHPVASNQSKEPAESAAVAH------ 82
           L P +  S P PS+ P+            +   A  PVAS+  + P E +  +       
Sbjct: 726 LAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG 785

Query: 83  --------------------ERPPGGTGSADPERPPG-ATCPESPGPG---PPHPLGVVE 118
                               +RPP   GSA P+ P G  + P SP      P + L    
Sbjct: 786 TLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG 845

Query: 119 SGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALP 178
           S   P  T       P G P   + T           +SP+  + LPP +  T S+  LP
Sbjct: 846 SKDSPATTHSPTPPSPKGAPTPSAVTP----------LSPK-GVTLPPKETPTPSVVNLP 894



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 38/140 (27%), Positives = 50/140 (35%), Gaps = 8/140 (5%)

Query: 36   PWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE 95
            P  +L+P   P+   PS + + A        A+  SKE +   AV      G     +  
Sbjct: 1544 PKEALIP---PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600

Query: 96   RPPGATCPESPGPGPPHPLGVVES-GKGP-PPTTEEEASGPPGEPR--LDSETESDHDDA 151
             PP  T P SP   P  P     S  KGP  P  +   + PP  P    DS T       
Sbjct: 1601 IPPAVTSP-SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659

Query: 152  FLSIMSPEIQLPLPPGKRRT 171
             +    P+    LP  K  T
Sbjct: 1660 KMGATVPQASKGLPAKKGPT 1679


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score =  154 bits (388), Expect = 9e-37
 Identities = 234/909 (25%), Positives = 331/909 (36%), Gaps = 158/909 (17%)

Query: 530  SAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATR 589
            S P+    SPA +  S A      +GT    E G    A   RP PP  G   + S A+ 
Sbjct: 165  SGPTPGTPSPAMARRSRA------AGT----EVGLPRPAPSARPRPPTEGPRKSVSSASE 214

Query: 590  FLPMDPATFRRKRPESVGGLEPPGP-------SVIAAPPSGGGNILQTLVLP--PNKEEQ 640
                +P+   R+RP + GGL+ P         + +++P   G +   T   P  P++ + 
Sbjct: 215  HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274

Query: 641  EGGGARVPSAPAPSLAYGAPA------APLSRPAATMVTNVVRPV-----SSTPVPIASK 689
            +G  A  P    P     APA      +PL+ P+ +      RPV     ++TP+P    
Sbjct: 275  KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK--ARPVPPPDNAATPLPATLP 332

Query: 690  PFPTSGR----AEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP---AP 742
            P P        A  SP+     +T     +  P  +P  ++        +  T P    P
Sbjct: 333  PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392

Query: 743  HLVAGPLLGTVGKAPATVTNL--LVGTPGYGAPAPPAVQ-FIAQGAPGGGTTAGSGAGAG 799
            H +  P L    +AP +   L  L  T   G+P   A   F+         +  S +   
Sbjct: 393  HSLTSPSL----QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA 448

Query: 800  SGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQ-QLQVAPAPAPAPGTKAAAP----- 853
            S P    PL               Q    LP  P  Q  ++PA +P        P     
Sbjct: 449  STPPDSPPL---------------QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493

Query: 854  --SGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGI----PILQSVPSAPPPKAQSVSPVQ 907
              +  +P   +   + P   T   +   +  TP      P L+++PS  PP  Q+ S   
Sbjct: 494  SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS--- 550

Query: 908  APPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPP-------FSVPVQNGAQPP 960
            AP      +  P     PL AP   +       P  + +PP        S P+Q    PP
Sbjct: 551  APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610

Query: 961  SKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTS 1020
               +  TP P + P   +PPL     P P S P   L   S +     +   H L    S
Sbjct: 611  LSPLA-TPPPQAPPXLALPPLQAPPSP-PASPPLSPLATPSPQAPNALAV--HLLQAPFS 666

Query: 1021 PASSQAGTVTSYGPTSSVALGFTSLGPSG--PAFVQPLLSAGQAPLLAPGQVGVSPVPSP 1078
            P  S       + P +S  +  ++  PS   P+   P L    +P  +P  +  S  P P
Sbjct: 667  PPPSPP-VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPP 724

Query: 1079 QLPPACAAPGGPVITAFYSGSPAPTSSAP--------LAQPSQAPPSLVYTVATSTTPPA 1130
            Q PP  AAP   V  +  +  P   S+ P         A P Q PPS   ++  S   P 
Sbjct: 725  QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS---PL 781

Query: 1131 ATILPKGPPAPAT----ATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
            A   P+ PPA AT    A P+P + FP     S + SL       P P+AP  + A +  
Sbjct: 782  AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTA--- 1243
            +P     +  +     APR+P  PGP    + P   L   P PP PP    + T +    
Sbjct: 842  VP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 897

Query: 1244 --RSSPPLPPPAEERTSAKGPETMASKFPSSSSD--------W-RVPGQGLENRGEP--- 1289
               SS     P E R    GPE  A+  P   ++        W R P   L  RG P   
Sbjct: 898  AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957

Query: 1290 -PTPP--------------------SPAPAP-AVAPGGSSESSSGRAAGDTPERKEAAGT 1327
             P PP                    S  PAP A+ PG S  +S G+A         AAG 
Sbjct: 958  LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKA---------AAGA 1008

Query: 1328 GKKVKVRPP 1336
            G     R P
Sbjct: 1009 GAGASSRSP 1017



 Score =  147 bits (370), Expect = 1e-34
 Identities = 219/858 (25%), Positives = 300/858 (34%), Gaps = 122/858 (14%)

Query: 507  RPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGS 566
            RPP  P PP P  P      G   A      +  +     AT           + +G  S
Sbjct: 28   RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87

Query: 567  TAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP------SVIAAP 620
                 RPP  G G  A P+K T   P+         P    G   PGP       + A  
Sbjct: 88   RNPASRPPASGRGERAPPAKNTSPGPV-------SSPGRASGTTRPGPLGQKGLRISAEE 140

Query: 621  PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVS 680
                G   +     P +     G  R  S P P    G P+  ++R +    T V  P  
Sbjct: 141  TVARGKATEA----PKRSALSAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP-- 190

Query: 681  STPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP 740
              P P A    PT G  ++  + +  + TE    +R    +  G+    S   S++AT  
Sbjct: 191  -RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 741  APHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGS 800
            +    +GP      +APA  +           P P  +Q +    P   T     A    
Sbjct: 250  SSPARSGPSARGTPRAPAHPSQ----------PKPKGLQAL---RPPQVTPPRKDAAPAL 296

Query: 801  GPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTT 860
            GP    PL    P    KA  +         LP  L   P+P  A     A PS  AP +
Sbjct: 297  GPLSSSPLATPSPSGT-KARPVPPPDNAATPLPATL--PPSPPLATPLPLAPPSPSAPPS 353

Query: 861  SIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAP---------PP 911
                  PP          AT P+   P + + P   PP  Q++ P+Q P          P
Sbjct: 354  LQTLPSPP----------ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403

Query: 912  GGSAQLLPGKVLVPLAAPSM----------------SVRGGGAGQPLPLVSPPFSVPVQN 955
                 L   +    L +P++                S+         P  SPP   P+  
Sbjct: 404  PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463

Query: 956  GAQPPSKIIQLTPV--PVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGH 1013
             A PP +   L+P   P+S+P  + P  + ++L   +  PQ  L  SS  +  +++    
Sbjct: 464  PASPPLQ-TSLSPAVSPLSSPLTIHPLQALSSL--ASHSPQAPL--SSLIMPPLETQSSL 518

Query: 1014 ALP-LGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQP------LLSAGQAPLLA 1066
            A P L T PAS     + +    +   L   S   + P    P       L A  +PL  
Sbjct: 519  APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578

Query: 1067 PGQVGVSPV--PSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVAT 1124
            P     S +  P PQ PPA A+P          G P+P  S     P QAPP L      
Sbjct: 579  PPPETPSSIATPPPQAPPALASPP-------LQGLPSPPLSPLATPPPQAPPXLALPPLQ 631

Query: 1125 STTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAI 1184
            +   P     P  PP    ATP+P +P   A      + L AP +  PSP   Q   +  
Sbjct: 632  APPSP-----PASPPLSPLATPSPQAPNALA-----VHLLQAPFSPPPSPPV-QAPFSPP 680

Query: 1185 ASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPL---PETWTP 1241
            AS PV       S  P      PL+  P   P +P       P P APPPL   P    P
Sbjct: 681  ASPPVSPSATPPSQAPPSLAAPPLQV-PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739

Query: 1242 TARSSPPL-----PPPAEERTSAKGPETMASKFPSS---SSDWRVPGQGLENRGEPPTPP 1293
            +  +SPP+     PPP      A  P  +    P+S   S   + P Q       PP   
Sbjct: 740  SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799

Query: 1294 SPAPAPAVAPGGSSESSS 1311
             P+P PA  PG +  S S
Sbjct: 800  LPSP-PASFPGQAPFSPS 816



 Score =  112 bits (281), Expect = 2e-24
 Identities = 265/1012 (26%), Positives = 354/1012 (34%), Gaps = 212/1012 (20%)

Query: 338  AERLHTVGG---PGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPK-PST 393
            AER   +GG   P SA PRA           G   S            PAS  G + P  
Sbjct: 59   AERAGGIGGATIPESA-PRA-----------GPTRSAGTSSRNPASRPPASGRGERAPPA 106

Query: 394  QYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVI 453
            +  +PGP ++PG        G       R S  +  A    T   +R  +      D   
Sbjct: 107  KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT-- 164

Query: 454  ADDGFGTTDIDLKCKERVTDSESG---DSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPL 510
            +    GT    +  + R   +E G    +    P       RK  S     S T      
Sbjct: 165  SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT------ 218

Query: 511  DPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKA-----QESGQG 565
            +P P     P    G G     S S SS A+  +S A S     GT +A     Q   +G
Sbjct: 219  EPSPAARRRPSA--GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 276

Query: 566  STAGPLRPP---PPG-----AGGP------ATPS----KATRFLPMD------PATFRRK 601
              A  LRPP   PP      A GP      ATPS    KA    P D      PAT    
Sbjct: 277  LQA--LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPS 334

Query: 602  RPESVG-GLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAP 660
             P +    L PP PS   APPS     LQTL  PP         A  PS   PS+     
Sbjct: 335  PPLATPLPLAPPSPS---APPS-----LQTLPSPP---------ATPPSQAPPSMTTPPM 377

Query: 661  AAPLSRPAATMVTNVVRPVSSTPVPIASKPFP-------------------TSGRAEASP 701
             AP   P+   +  +  P S T   + + P P                   T      SP
Sbjct: 378  QAP---PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434

Query: 702  NDTAGARTEMGTGSRVPGGSP---LGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPA 758
              T  + T     +  P  SP     +SL  S     +  SPA   ++ PL     +A +
Sbjct: 435  RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL-SPAVSPLSSPLTIHPLQALS 493

Query: 759  TVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGK 818
            ++ +     P      PP     +   P   T   S     + P   +P   L P  L  
Sbjct: 494  SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS---LTTPPLENLPS--LAPPPLQT 548

Query: 819  AGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAP-SGPAPTTSIRFTLPPGTSTNGKVL 877
            A          P     L+  P PAP P     +P + P P T      PP  +      
Sbjct: 549  ASA--------PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA--- 597

Query: 878  AATAPTPGIPILQSVPSA-PPPKAQ---SVSPVQAPP-PGGSAQLLPGKVLVPLAAPSMS 932
             A+ P  G+P     P A PPP+A    ++ P+QAPP P  S  L P     P A  +++
Sbjct: 598  LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA 657

Query: 933  V---RGGGAGQPLPLV----SPPFSVPVQNGAQPPSKI--------IQLTPVPVSTP--- 974
            V   +   +  P P V    SPP S PV   A PPS+         +Q+ P P ++P   
Sbjct: 658  VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717

Query: 975  -SGLVPPLSPATL--------PGPTSQPQKVLLPSST---RITYVQSAGGHALPLGTSPA 1022
             S   PP +P  L        P P + P   + PS+T   R+  + +A    +P  + PA
Sbjct: 718  PSATPPPQAPPPLAAPPLQVPPSPPASPP--MSPSATPPPRVPPLLAAPPLQVP-PSPPA 774

Query: 1023 SSQAGTVTSYGPTSSVALGFTSLG--PSGPAFVQPLLSAGQAPLLAPGQVGVSPV--PSP 1078
            S     +    P +  AL    L   PS PA        GQAP      + +SP+  P P
Sbjct: 775  SLPMSPLAKPPPQAPPALATPPLQALPSPPASFP-----GQAPFSPSASLPMSPLATPPP 829

Query: 1079 QLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAP------PSLVYTVATSTTPP--- 1129
            Q PP  AAP   ++    S   +PT  AP   P+  P      P L   +A    PP   
Sbjct: 830  QAPPVLAAP---LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 886

Query: 1130 ----------------AATILPK-------GPPAPATATPAPTSPFPSATAGSMTYSLVA 1166
                            +AT  P+       GP   A A+P P +   +    + +     
Sbjct: 887  SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 946

Query: 1167 PKAQRPSPKAPQKVKAAIAS------IPVGSFEAGASGRPGPAPRQPLEPGP 1212
            P A R +P AP     A           +   E   S  P P     L+PGP
Sbjct: 947  PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG---ALDPGP 995



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 158/670 (23%), Positives = 231/670 (34%), Gaps = 96/670 (14%)

Query: 973  TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSY 1032
            TP+   P L     PG    P  V  P++ R+       G A  +G  P + +AG +   
Sbjct: 16   TPAARAPGLLTPRPPGSPRPPPPVT-PAALRVL------GAAGAVGRKPLAERAGGIGG- 67

Query: 1033 GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVI 1092
               +++       GP+  A       A + P    G+         + PPA     GPV 
Sbjct: 68   ---ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE---------RAPPAKNTSPGPVS 115

Query: 1093 TAFYSGSPAPTSSAPLAQPSQAPPSLVYTVAT--STTPPAATILPKGP----PAPATATP 1146
            +     +   T   PL Q      S   TVA   +T  P  + L  G       P   TP
Sbjct: 116  SP--GRASGTTRPGPLGQKGLRI-SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172

Query: 1147 APTSPFPSATAGS-MTYSLVAPKAQ-RPSPKAPQKVKAAIASIPVGSFEAGASGRPG--- 1201
            +P     S  AG+ +     AP A+ RP  + P+K  ++ +          A  RP    
Sbjct: 173  SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232

Query: 1202 ----PAPRQPLEPG-PVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEER 1256
                PA R       P+  P        G P  PA P  P+     A   P + PP ++ 
Sbjct: 233  GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292

Query: 1257 TSAKGPETMASKFPSSSSDWRVPG-QGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAA 1315
              A GP         SSS    P   G + R  PP   +  P PA  P     ++    A
Sbjct: 293  APALGP--------LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA 344

Query: 1316 GDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPT 1375
              +P    +  T     +  PP      +  +     +        +P  +    L SP+
Sbjct: 345  PPSPSAPPSLQT-----LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399

Query: 1376 LQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSS--EPNTPKSAKCE 1433
            LQ+   SP A+        + +T L S     T     M  R + +S   P+ P S   +
Sbjct: 400  LQA-PPSPLAL-----SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453

Query: 1434 GDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAF 1493
                    +   +  +   L     P SS   T+   +AL            S+ A+ + 
Sbjct: 454  SPPLQAPLSLPASPPLQTSLSPAVSPLSS-PLTIHPLQAL------------SSLASHSP 500

Query: 1494 QARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTP-- 1551
            QA  + +    +  Q  +     +   A+  T  PP    P   PPP  TA+AP  TP  
Sbjct: 501  QAPLSSLIMPPLETQSSLAPPSLQTPPASLTT--PPLENLPSLAPPPLQTASAPLTTPHL 558

Query: 1552 ---------------SPAGGPDPTSPSSDSGTAQAAPP-LPPPPESGPGQPGWEGAPQPS 1595
                           SP   P P +PSS +     APP L  PP  G   P    +P  +
Sbjct: 559  ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL--SPLAT 616

Query: 1596 PPPPGPSTAA 1605
            PPP  P   A
Sbjct: 617  PPPQAPPXLA 626



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 105/372 (28%), Positives = 132/372 (35%), Gaps = 48/372 (12%)

Query: 508  PPLDPEPPGPPD-PPVAFGKGYGSAPSSSASSPASSSASAATSFS--LGSGTFKAQESGQ 564
            PP+ P    PP  PP          PS  AS P S SA+        L +   +   S  
Sbjct: 714  PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773

Query: 565  GSTA-GPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIA---AP 620
             S    PL  PPP A  PA  +   + LP  PA+F  + P S     P  P       AP
Sbjct: 774  ASLPMSPLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832

Query: 621  PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAP-----------SLAYGAPAAPLSRPAA 669
            P     +LQ    PP     +    R P  P P           +LA G P  P   P++
Sbjct: 833  PVLAAPLLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890

Query: 670  TM----VTNVVRPVSSTPVPIASKPF-PTSGRAEASPNDTAGARTEMGTGSRVPGGSPLG 724
            T+    +       +STP  +      P  G A + P D   A       SR P   PL 
Sbjct: 891  TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA-PPLA 949

Query: 725  VSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ-FIAQ 783
                   + +  A  P P    GP     G A    T      P    PAP A+    + 
Sbjct: 950  F------RGAPGAPLPWPP-ATGP-----GSADGLCTIYETEGPESATPAPGALDPGPSP 997

Query: 784  GAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPA 843
            G  GG   AG+GAGA S       LG L  GAL       Q   +   L + L +A A  
Sbjct: 998  GTSGGKAAAGAGAGASSRSPKQARLGELPLGAL-------QASVVQHLLSRTLLLAAAEG 1050

Query: 844  PAPGTKAAAPSG 855
             A G+    P G
Sbjct: 1051 AAGGS-GGGPGG 1061



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 94/326 (28%), Positives = 116/326 (35%), Gaps = 62/326 (19%)

Query: 508  PPLDPEPP--GPPDPPVAFGKGYGSAP-SSSASSPASSSASAATSFS--LGSGTFKAQES 562
            PP    PP    P PP +F    G AP S SAS P S  A+        L +   +   S
Sbjct: 789  PPALATPPLQALPSPPASFP---GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845

Query: 563  GQGSTA--GPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPES-VGGLEPPGPSVIAA 619
               S     P RPP PG     +  + T  L   P     + P S + G +  G S  A 
Sbjct: 846  PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 905

Query: 620  P-----------PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAY-GAPAAPLSRP 667
                        P GG         PP+ E      A     PAP LA+ GAP APL  P
Sbjct: 906  STPEELRGYDSGPEGGAAASP----PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961

Query: 668  AAT---------MVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVP 718
             AT          +     P S+TP P A  P P+ G +       AGA    G  SR P
Sbjct: 962  PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA----GASSRSP 1017

Query: 719  GGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAV 778
              + LG   +      A   S   HL++  LL    +  A  +    G PG         
Sbjct: 1018 KQARLGELPL-----GALQASVVQHLLSRTLLLAAAEGAAGGSG---GGPG--------- 1060

Query: 779  QFIAQGAPGGGTTAGSGAGAGSGPNG 804
                 GA GGG T G+ A       G
Sbjct: 1061 -----GAEGGGVTGGARAALSDAELG 1081



 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 102/420 (24%), Positives = 140/420 (33%), Gaps = 76/420 (18%)

Query: 1193 EAGASGRPGPAPRQP--LEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLP 1250
            +AGA+ R  PA R P  L P P            G P PP PP  P        +     
Sbjct: 9    KAGAAART-PAARAPGLLTPRP-----------PGSPRPP-PPVTPAALRVLGAAGAVGR 55

Query: 1251 PPAEERTSAKGPETMASKFP------SSSSDWRVPGQG--LENRGE-PPTPPSPAPAPAV 1301
             P  ER    G  T+    P      S+ +  R P        RGE  P   + +P P  
Sbjct: 56   KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115

Query: 1302 APGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAE 1361
            +PG +S ++     G    R  A  T  + K    P +    +   R  S          
Sbjct: 116  SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG--------- 166

Query: 1362 LPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTS-PKRKMRRRSSC 1420
                 P    PSP +   + +    +G  R          + P  PT  P++ +   S  
Sbjct: 167  -----PTPGTPSPAMARRSRAAGTEVGLPRPAPS------ARPRPPTEGPRKSVSSASEH 215

Query: 1421 SSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQD 1480
            S+   +P + +         R  + +      L     P SS  R+              
Sbjct: 216  STTEPSPAARRRPSAGGGLQRPASRS------LSSSATPLSSPARS-------------- 255

Query: 1481 HGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPP 1540
                PSA+ T    A  +   P K    L+  +V      AA      P + +PL  P P
Sbjct: 256  ---GPSARGTPRAPAHPSQPKP-KGLQALRPPQVTPPRKDAAPALG--PLSSSPLATPSP 309

Query: 1541 TGTAAAPAPTPSPAGGPDP-TSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPP 1599
            +GT A P P P  A  P P T P S       A PLP  P S    P  +  P P   PP
Sbjct: 310  SGTKARPVPPPDNAATPLPATLPPS----PPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 34/87 (39%), Positives = 39/87 (44%), Gaps = 12/87 (13%)

Query: 1522 ATPTEQPPGA------EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPL 1575
            ATP+ Q P A      +AP   PP     A  +P  SP   P  T PS  +  + AAPPL
Sbjct: 646  ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ-APPSLAAPPL 704

Query: 1576 ---PPPPESGPGQPGWEGAPQPSPPPP 1599
               P PP S P  P     P P  PPP
Sbjct: 705  QVPPSPPASPPMSPS--ATPPPQAPPP 729



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 34/108 (31%), Positives = 44/108 (40%), Gaps = 21/108 (19%)

Query: 1521 AATPTEQPPGAEAPLPV-----PPPTGTAAAPAP----TPSPAGGPDPTSPSSDSGTAQA 1571
            AA P + PP   A LP+     PPP    A   P     PSP       +P S S +   
Sbjct: 762  AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821

Query: 1572 APPLPPPPESGP--GQPGWEGAPQP----------SPPPPGPSTAATG 1607
            +P   PPP++ P    P  +  P P           PP PGP T+ +G
Sbjct: 822  SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 21/110 (19%)

Query: 1518 IMQAATPTEQ-PPGAEAP---LPVPPPTGTAAAPAPTPSPAGGP---------DPTSPSS 1564
            +  +ATP  Q PP   AP   +P  PP     +P+ TP P   P          P+ P+S
Sbjct: 685  VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744

Query: 1565 DSGTAQAAPP--LPP----PPESGPGQP--GWEGAPQPSPPPPGPSTAAT 1606
               +  A PP  +PP    PP   P  P      +P   PPP  P   AT
Sbjct: 745  PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 31/113 (27%)

Query: 1521 AATPTEQPPGAEAPL----PVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLP 1576
            A  P + PP   APL    P PP + T  AP   P+P  GPD TS S    T   AP  P
Sbjct: 825  ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP--GPD-TSVSGPRLTLALAPGPP 881

Query: 1577 PPPESGPGQP---------------------GWEGAPQ---PSPPPPGPSTAA 1605
            PPP   P                        G++  P+    + PPP    AA
Sbjct: 882  PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 17/94 (18%)

Query: 1521 AATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPP---LPP 1577
            A  P   PP   AP    PP+  A+ P    SP   P P +P      A A PP   LP 
Sbjct: 751  ATPPPRVPPLLAAPPLQVPPSPPASLPM---SPLAKPPPQAP-----PALATPPLQALPS 802

Query: 1578 PPESGPGQPGWEG------APQPSPPPPGPSTAA 1605
            PP S PGQ  +        +P  +PPP  P   A
Sbjct: 803  PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836



 Score = 40.4 bits (93), Expect = 0.014
 Identities = 43/151 (28%), Positives = 56/151 (37%), Gaps = 20/151 (13%)

Query: 29  PRSVAVFPWHSL-VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPG 87
           P ++AV   H L  PF  P  P      S    P   P A+  S+ P   AA   + PP 
Sbjct: 653 PNALAV---HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 709

Query: 88  GTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESD 147
              S  P  P     P++P P    PL V  S    PP +   A+ PP  P L       
Sbjct: 710 PPASP-PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS-PSATPPPRVPPL------- 760

Query: 148 HDDAFLSIMSPEIQLPLPPGKRRTQSLSALP 178
                  + +P +Q+P  P      S  A P
Sbjct: 761 -------LAAPPLQVPPSPPASLPMSPLAKP 784



 Score = 39.7 bits (91), Expect = 0.024
 Identities = 40/123 (32%), Positives = 43/123 (34%), Gaps = 41/123 (33%)

Query: 1522 ATPTEQPPGAEAPLPVP------PPTGTAAAPAPTPSPA-------GGPDPTSPSS---- 1564
            A+PT Q P    P P P      P    A AP P P P+        GPD    SS    
Sbjct: 848  ASPTLQAP-RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 906

Query: 1565 --------DSGTAQAAPPLPPPP-----------ESGPGQP----GWEGAPQPSPPPPGP 1601
                    DSG    A   PPP              GP  P    G  GAP P PP  GP
Sbjct: 907  TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 966

Query: 1602 STA 1604
             +A
Sbjct: 967  GSA 969



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 43/153 (28%), Positives = 65/153 (42%), Gaps = 17/153 (11%)

Query: 29  PRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGG 88
           P S+A  P     P   P+   P +Q   +  P   P+A+   + P   A    + PP  
Sbjct: 584 PSSIATPP-----PQAPPALASPPLQGLPS--PPLSPLATPPPQAPPXLALPPLQAPP-- 634

Query: 89  TGSADPERPPGATCPESPGPGPPHPLGV--VESGKGPPPTTEEEAS-GPPGEPRLDSETE 145
           +  A P   P AT    P P  P+ L V  +++   PPP+   +A   PP  P + S + 
Sbjct: 635 SPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSA 689

Query: 146 SDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALP 178
           +    A  S+ +P +Q+P  P      S SA P
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722



 Score = 38.5 bits (88), Expect = 0.053
 Identities = 29/101 (28%), Positives = 35/101 (34%), Gaps = 21/101 (20%)

Query: 1521 AATPTEQPPGAEAP---LPVPPPTGTAAAPAPTPSPAG-------------GPDPTSPSS 1564
            A  P + PP    P    P  PP     +P  TPSP                P P+ P  
Sbjct: 615  ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674

Query: 1565 DSGTAQAAPPLPP---PPESGPGQPGWEGAPQPSPPPPGPS 1602
               +  A+PP+ P   PP   P  P     P   PP P  S
Sbjct: 675  APFSPPASPPVSPSATPPSQAP--PSLAAPPLQVPPSPPAS 713



 Score = 36.6 bits (83), Expect = 0.20
 Identities = 36/128 (28%), Positives = 47/128 (36%), Gaps = 26/128 (20%)

Query: 46  PSQPDPS----------VQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE 95
           PSQP P             P +   PA  P++S+    P+ S   A   PP    +    
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT--- 325

Query: 96  RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSI 155
            P  AT P SP    P PL         PP+     S PP    L S   +    A  S+
Sbjct: 326 -PLPATLPPSPPLATPLPLA--------PPS----PSAPPSLQTLPSPPATPPSQAPPSM 372

Query: 156 MSPEIQLP 163
            +P +Q P
Sbjct: 373 TTPPMQAP 380



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 37/141 (26%), Positives = 49/141 (34%), Gaps = 9/141 (6%)

Query: 29  PRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGG 88
           P S +  P   + P LA   P   V PS        P+A    + P   A    +  P  
Sbjct: 746 PMSPSATPPPRVPPLLAA--PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803

Query: 89  TGSADPERP--PGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETES 146
             S   + P  P A+ P SP   PP     V +     P  +   S PP  P L +    
Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA----PLLQVPPS-PPASPTLQAPRRP 858

Query: 147 DHDDAFLSIMSPEIQLPLPPG 167
                  S+  P + L L PG
Sbjct: 859 PTPGPDTSVSGPRLTLALAPG 879



 Score = 31.6 bits (70), Expect = 6.5
 Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 8/138 (5%)

Query: 3   SAHRPLMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPA 62
           ++H P  P SS     L     +++ P S+   P     P   P +  PS+ P   Q  A
Sbjct: 496 ASHSPQAPLSSLIMPPLE--TQSSLAPPSLQTPPASLTTP---PLENLPSLAPPPLQT-A 549

Query: 63  SHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKG 122
           S P+ +   + P   A    + PP    +  PE P     P  P   PP        G  
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP--PPQAPPALASPPLQGLP 607

Query: 123 PPPTTEEEASGPPGEPRL 140
            PP +      P   P L
Sbjct: 608 SPPLSPLATPPPQAPPXL 625


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score =  142 bits (359), Expect = 2e-33
 Identities = 221/822 (26%), Positives = 300/822 (36%), Gaps = 150/822 (18%)

Query: 569  GPLRPPPPGAGGPATP--SKATRFLPMDPATFRR---KRPESVGGLEPPGPSVIAAPPSG 623
            G L P PPG+  P  P    A R L    A  R+   +R   +GG   P  +  A P   
Sbjct: 23   GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRS 82

Query: 624  GGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTP 683
             G   +    P ++    G G R P  PA + + G    P+S P     T    P+    
Sbjct: 83   AGTSSRN---PASRPPASGRGERAP--PAKNTSPG----PVSSPGRASGTTRPGPLGQKG 133

Query: 684  VPIASKPFPTSGRAEASPNDTAGARTEMGTGSR--VPGGSPLGVSLVYSDKKSAAATS-- 739
            + I+++     G+A  +P      R+ +  G+R    G +P   S   + +  AA T   
Sbjct: 134  LRISAEETVARGKATEAPK-----RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188

Query: 740  -PAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGA 798
             P P   A P   T G   +      V +    +   P+     + + GGG    +    
Sbjct: 189  LPRPAPSARPRPPTEGPRKS------VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242

Query: 799  GSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQ--LQVAPAPAPAPGTKAAAPS-G 855
             S      PL    P   G +   T      P+ P+   LQ    P   P  K AAP+ G
Sbjct: 243  SSSAT---PLS--SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297

Query: 856  PAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSA 915
            P  ++      P  T +    L + AP    P L + P +     Q  +P+   PP    
Sbjct: 298  PLSSS------PLATPSPSAALQSQAP----PTLPATPHSSSLTCQLATPLPLAPPS--- 344

Query: 916  QLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPS 975
                     P A PS+        Q LP  SPP + P Q      S  +Q T   + +P 
Sbjct: 345  ---------PSAPPSL--------QTLP--SPPATPPSQATTSLGSPTLQATHSFLPSP- 384

Query: 976  GLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPT 1035
                PLSP   P P + P   L P              A P  + PAS     + +  P 
Sbjct: 385  ----PLSPLATPPPQAPPALALPPLQ------------APP--SPPASPPLSPLATPSPQ 426

Query: 1036 SSVALGFTSL-GPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSP--QLPPACAAPGGPVI 1092
            +  AL    L  P  P    P+    QAP   P    VSP  +P  Q PP+ AAP   V 
Sbjct: 427  APNALAVHLLQAPFSPPPSPPV----QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV- 481

Query: 1093 TAFYSGSPAPTSSAPLAQ----PSQAPPSLVYTVATSTTPPAATILPKGPPAPAT----A 1144
                   P+P +S P++     P QAPP L         PP     P+ PPA AT    A
Sbjct: 482  ------PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP-----PQAPPALATPPLQA 530

Query: 1145 TPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAP 1204
             P+P + FP     S + SL       P P+AP  + A +  +P     +  +     AP
Sbjct: 531  LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPTLQAP 586

Query: 1205 RQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPT-----ARSSPPLPPPAEERTSA 1259
            R+P  PGP    + P   L   P PP PP    + T +       SS     P E R   
Sbjct: 587  RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 646

Query: 1260 KGPETMASKFPSSSSD--------W-RVPGQGLENRGEP--PTPPSPAPAPAVAPG---- 1304
             GPE  A+  P   ++        W R P   L  RG P  P P  PA  P  A G    
Sbjct: 647  SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI 706

Query: 1305 ----GSSESSSGRAAGD------TPERKEAAGTGKKVKVRPP 1336
                G   ++    A D      T   K AAG G     R P
Sbjct: 707  YETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748



 Score =  131 bits (330), Expect = 5e-30
 Identities = 186/748 (24%), Positives = 265/748 (35%), Gaps = 91/748 (12%)

Query: 507  RPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGS 566
            RPP  P PP P  P      G   A      +  +     AT           + +G  S
Sbjct: 28   RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87

Query: 567  TAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP------SVIAAP 620
                 RPP  G G  A P+K T   P+         P    G   PGP       + A  
Sbjct: 88   RNPASRPPASGRGERAPPAKNTSPGPVSS-------PGRASGTTRPGPLGQKGLRISAEE 140

Query: 621  PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVS 680
                G   +     P +     G  R  S P P    G P+  ++R +    T V  P  
Sbjct: 141  TVARGKATEA----PKRSALSAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP-- 190

Query: 681  STPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP 740
              P P A    PT G  ++  + +  + TE    +R    +  G+    S   S++AT  
Sbjct: 191  -RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 741  APHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGS 800
            +    +GP      +APA  +           P P  +Q +    P   T     A    
Sbjct: 250  SSPARSGPSARGTPRAPAHPSQ----------PKPKGLQALR---PPQVTPPRKDAAPAL 296

Query: 801  GPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQ----------LQVAPAPAPAPGTKA 850
            GP    PL    P A  ++    Q    LP  P            L +AP    AP +  
Sbjct: 297  GPLSSSPLATPSPSAALQS----QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ 352

Query: 851  AAPSGPAPTTSIRFTLPPGTSTNGKVLAAT---APTPGIPILQSVPSAPPPKAQSVSPVQ 907
              PS PA   S        TS     L AT    P+P +  L + P   PP A ++ P+Q
Sbjct: 353  TLPSPPATPPS-----QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP-ALALPPLQ 406

Query: 908  APP-PGGSAQLLPGKVLVPLAAPSMSV---RGGGAGQPLPLV----SPPFSVPVQNGAQP 959
            APP P  S  L P     P A  +++V   +   +  P P V    SPP S PV   A P
Sbjct: 407  APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466

Query: 960  PSKI---IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALP 1016
            PS+    +   P+ V       PP+SP+  P P + P     P        Q+    A P
Sbjct: 467  PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526

Query: 1017 ----LGTSPASSQAGTVTSYGPTSSVALGFTSLGP--SGPAFVQPLLSAGQAPLLAPGQV 1070
                L + PAS        + P++S+ +   +  P  + P    PLL    +P  +P   
Sbjct: 527  PLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 584

Query: 1071 GVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPA 1130
                 P+P   P  +  G  +  A   G P P S +P +  S  P    ++ + ++TP  
Sbjct: 585  APRRPPTPG--PDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSSSATSTPEE 641

Query: 1131 ATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS---- 1186
                  GP   A A+P P +   +    + +     P A R +P AP     A       
Sbjct: 642  LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701

Query: 1187 --IPVGSFEAGASGRPGPAPRQPLEPGP 1212
                +   E   S  P P     L+PGP
Sbjct: 702  GLCTIYETEGPESATPAPG---ALDPGP 726



 Score =  103 bits (256), Expect = 2e-21
 Identities = 169/678 (24%), Positives = 231/678 (34%), Gaps = 135/678 (19%)

Query: 642  GGGARVPSAPAPSLAYGAPAA-----PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGR 696
            G  AR P+A AP L    P       P   PAA  V      V   P+   +     +  
Sbjct: 11   GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 697  AEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKA 756
             E++P   AG     GT SR P   P   S        A  TSP P    G   GT    
Sbjct: 71   PESAPR--AGPTRSAGTSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127

Query: 757  PATVTNLLVGTPGYGAPAPPAVQFIAQG-APGGGTTAGSGAGAGSGPNGPVPLGILQPGA 815
            P     L +           A + +A+G A      +   AGA    +GP P G   P A
Sbjct: 128  PLGQKGLRIS----------AEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSP-A 175

Query: 816  LGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGK 875
            + +       +  LP         PAP+  P      P     + S   T  P  +   +
Sbjct: 176  MARRSRAAGTEVGLPR--------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227

Query: 876  VLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRG 935
              A        P  +S+ S+  P +   SP ++ P        P       A PS     
Sbjct: 228  PSAGGGLQR--PASRSLSSSATPLS---SPARSGPSARGTPRAP-------AHPSQPKPK 275

Query: 936  GGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQK 995
            G     L  + PP   P +  A P    +  +P+   +PS  +   +P TLP        
Sbjct: 276  G-----LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPAT------ 324

Query: 996  VLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQP 1055
               P S+ +T        A PL  +P S                       PS P  +Q 
Sbjct: 325  ---PHSSSLTCQL-----ATPLPLAPPS-----------------------PSAPPSLQT 353

Query: 1056 LLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAP 1115
            L S    P   P Q             A  + G P + A +S  P+P  S     P QAP
Sbjct: 354  LPSPPATP---PSQ-------------ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397

Query: 1116 PSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPK 1175
            P+L      +   P     P  PP    ATP+P +P   A      + L AP +  PSP 
Sbjct: 398  PALALPPLQAPPSP-----PASPPLSPLATPSPQAPNALAV-----HLLQAPFSPPPSPP 447

Query: 1176 APQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPL 1235
              Q   +  AS PV      ++  P  AP           P+     L+  P+PPA PP+
Sbjct: 448  V-QAPFSPPASPPVSP----SATPPSQAP-----------PSLAAPPLQVPPSPPASPPM 491

Query: 1236 PETWTPTARSSPPL--------PPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRG 1287
              + TP  ++ PPL         PP +   +   P   A   P +S   + P     +  
Sbjct: 492  SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551

Query: 1288 EPP--TPPSPAPAPAVAP 1303
              P  TPP  AP    AP
Sbjct: 552  MSPLATPPPQAPPVLAAP 569



 Score = 97.8 bits (242), Expect = 7e-20
 Identities = 213/874 (24%), Positives = 300/874 (34%), Gaps = 186/874 (21%)

Query: 338  AERLHTVGG---PGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPK-PST 393
            AER   +GG   P SA PRA           G   S            PAS  G + P  
Sbjct: 59   AERAGGIGGATIPESA-PRA-----------GPTRSAGTSSRNPASRPPASGRGERAPPA 106

Query: 394  QYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVI 453
            +  +PGP ++PG        G       R S  +  A    T   +R  +          
Sbjct: 107  KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL---------- 156

Query: 454  ADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPE 513
                              +     D+SG  P    G      +   R++ T    P  P 
Sbjct: 157  ------------------SAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP-RPA 193

Query: 514  PPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRP 573
            P   P PP    +   S  S+S  S    S +A    S G G  +       S+A PL  
Sbjct: 194  PSARPRPPTEGPR--KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL-- 249

Query: 574  PPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVL 633
                   PA    + R  P  PA   + +P+ +  L PP                   V 
Sbjct: 250  -----SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP------------------QVT 286

Query: 634  PPNKEEQEGGGARVPS---APAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIA--S 688
            PP K+     G    S    P+PS A  + A P + PA    +++   + +TP+P+A  S
Sbjct: 287  PPRKDAAPALGPLSSSPLATPSPSAALQSQAPP-TLPATPHSSSLTCQL-ATPLPLAPPS 344

Query: 689  KPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP--APHLVA 746
               P S +   SP  T  ++     GS     +    S + S   S  AT P  AP  +A
Sbjct: 345  PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH---SFLPSPPLSPLATPPPQAPPALA 401

Query: 747  GPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPV 806
             P L      PA+     + TP   AP   AV  +              A     P+ PV
Sbjct: 402  LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-------------APFSPPPSPPV 448

Query: 807  PLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTL 866
                             Q  +  P  P     A  P+ AP + AA P            +
Sbjct: 449  -----------------QAPFSPPASPPVSPSATPPSQAPPSLAAPP----------LQV 481

Query: 867  PPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGS--AQLLPGKVLV 924
            PP    +  +  +  P P  P     P A PP   +  P QAPP   +   Q LP     
Sbjct: 482  PPSPPASPPMSPSATPPPQAP----PPLAAPPLQLAKPPPQAPPALATPPLQALPSP--- 534

Query: 925  PLAAPSMSVRGGGAGQPL-PLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSP 983
            P + P  +     A  P+ PL +PP   P    A     ++Q+ P P ++P+ L  P  P
Sbjct: 535  PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA----PLLQVPPSPPASPT-LQAPRRP 589

Query: 984  ATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFT 1043
             T PGP +        S  R+T        AL  G  P  S++ + T  GP  +   G +
Sbjct: 590  PT-PGPDTS------VSGPRLTL-------ALAPGPPPPPSRSPSSTLSGPDLA---GHS 632

Query: 1044 SLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLP---PACAAPGGPVITAFYSGSP 1100
            S   S P   + L      P    G    SP P  +L    PA  + G     AF     
Sbjct: 633  SSATSTP---EELRGYDSGP---EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686

Query: 1101 APTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSM 1160
            AP    P   P  A    + T+  +  P +AT      PAP    P P+      T+G  
Sbjct: 687  APLPWPPATGPGSADG--LCTIYETEGPESAT------PAPGALDPGPS----PGTSGGK 734

Query: 1161 TYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEA 1194
              +     A   SPK     +A +  +P+G+ +A
Sbjct: 735  AAAGAGAGASSRSPK-----QARLGELPLGALQA 763



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 148/571 (25%), Positives = 196/571 (34%), Gaps = 114/571 (19%)

Query: 1059 AGQAP-LLAPGQVGVSPVPSPQLPPAC-------AAPGGPVITAFYSGSPAPT--SSAPL 1108
            A +AP LL P   G SP P P + PA         A G   +     G    T   SAP 
Sbjct: 18   AARAPGLLTPRPPG-SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76

Query: 1109 AQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPK 1168
            A P+++  +     A+   PPA+    + PPA  T+ P P S  P   +G+     +  K
Sbjct: 77   AGPTRSAGTSSRNPASR--PPASGRGERAPPAKNTS-PGPVSS-PGRASGTTRPGPLGQK 132

Query: 1169 AQRPSPKAPQKVKAAIASIPVGSFEAGAS-GRPGPAPRQPLEPGPVREPTAPESELEGQP 1227
              R S +       A  +    +  AGA     GP P  P  P   R   A  +E+ G P
Sbjct: 133  GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEV-GLP 190

Query: 1228 TPPAPPPLPETWTPTARSSPPLPPPAEERTSAKG-----PETMASKFPSSSSDWRVPGQG 1282
             P           P+AR  PP   P +  +SA       P   A + PS+       G G
Sbjct: 191  RP----------APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-------GGG 233

Query: 1283 LENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTF 1342
            L+         S  P  + A  G S   + RA     + K       +     PP K   
Sbjct: 234  LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293

Query: 1343 DSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDS 1402
             ++     S +      A L    P  +  +P   SL               + +T L  
Sbjct: 294  PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC-------------QLATPLPL 340

Query: 1403 APEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSS 1462
            AP  P++P        +  S P TP S               +A   LG          +
Sbjct: 341  APPSPSAPPSLQ----TLPSPPATPPS---------------QATTSLGS--------PT 373

Query: 1463 LRRTLDQRRALVMQLFQDHGFFPSAQ----ATAAFQARYADIFPSKVCLQLKIRE-VRQK 1517
            L+ T              H F PS      AT   QA  A   P    LQ          
Sbjct: 374  LQAT--------------HSFLPSPPLSPLATPPPQAPPALALPP---LQAPPSPPASPP 416

Query: 1518 IMQAATPTEQPPGA------EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQA 1571
            +   ATP+ Q P A      +AP   PP     A  +P  SP   P  T PS  +  + A
Sbjct: 417  LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ-APPSLA 475

Query: 1572 APPL---PPPPESGPGQPGWEGAPQPSPPPP 1599
            APPL   P PP S P  P     P P  PPP
Sbjct: 476  APPLQVPPSPPASPPMSPS--ATPPPQAPPP 504



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 164/700 (23%), Positives = 229/700 (32%), Gaps = 117/700 (16%)

Query: 973  TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSY 1032
            TP+   P L     PG    P  V  P++ R+       G A  +G  P + +AG +   
Sbjct: 16   TPAARAPGLLTPRPPGSPRPPPPVT-PAALRVL------GAAGAVGRKPLAERAGGIGG- 67

Query: 1033 GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVI 1092
               +++       GP+  A       A + P    G+         + PPA     GPV 
Sbjct: 68   ---ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE---------RAPPAKNTSPGPVS 115

Query: 1093 TAFYSGSPAPTSSAPLAQPSQAPPSLVYTVAT--STTPPAATILPKGP----PAPATATP 1146
            +     +   T   PL Q      S   TVA   +T  P  + L  G       P   TP
Sbjct: 116  SP--GRASGTTRPGPLGQKGLRI-SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172

Query: 1147 APTSPFPSATAGS-MTYSLVAPKAQ-RPSPKAPQKVKAAIASIPVGSFEAGASGRPG--- 1201
            +P     S  AG+ +     AP A+ RP  + P+K  ++ +          A  RP    
Sbjct: 173  SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232

Query: 1202 ----PAPRQPLEPG-PVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEER 1256
                PA R       P+  P        G P  PA P  P+     A   P + PP ++ 
Sbjct: 233  GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292

Query: 1257 TSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSP----------APAPAVAPGGS 1306
              A GP        SS      P   L+++  P  P +P           P P   P  S
Sbjct: 293  APALGP------LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346

Query: 1307 SESSSGRAAGD--TPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEV-----DFEERF 1359
            +  S         TP  +     G       P L+ T   + +  LS +           
Sbjct: 347  APPSLQTLPSPPATPPSQATTSLGS------PTLQATHSFLPSPPLSPLATPPPQAPPAL 400

Query: 1360 AELPEFRPEEVLPSPTLQSLAT-SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRS 1418
            A  P   P     SP L  LAT SP+A           +  L  AP  P          S
Sbjct: 401  ALPPLQAPPSPPASPPLSPLATPSPQA-------PNALAVHLLQAPFSPPPSPPVQAPFS 453

Query: 1419 SCSSEPNTPKS---AKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVM 1475
              +S P +P +   ++    +         +      +     P       L    A  +
Sbjct: 454  PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL---AAPPL 510

Query: 1476 QLFQDHGFFPSAQATAAFQARYAD--IFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEA 1533
            QL +     P A AT   QA  +    FP +             +  A  P + PP   A
Sbjct: 511  QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL--ATPPPQAPPVLAA 568

Query: 1534 PL----PVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQP--- 1586
            PL    P PP + T  AP   P+P  GPD TS S    T   AP  PPPP   P      
Sbjct: 569  PLLQVPPSPPASPTLQAPRRPPTP--GPD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625

Query: 1587 ------------------GWEGAPQ---PSPPPPGPSTAA 1605
                              G++  P+    + PPP    AA
Sbjct: 626  PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 665



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 103/382 (26%), Positives = 135/382 (35%), Gaps = 56/382 (14%)

Query: 496 SPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSG 555
           SP +++ F+   PP  P       PP         AP S A+ P     S   S  +   
Sbjct: 445 SPPVQAPFS---PPASPPVSPSATPP-------SQAPPSLAAPPLQVPPSPPASPPMSPS 494

Query: 556 TFKAQESGQGSTAGPLR--PPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPG 613
                ++     A PL+   PPP A  PA  +   + LP  PA+F  + P S     P  
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMS 553

Query: 614 PSVIA---APPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAP-----------SLAYGA 659
           P       APP     +LQ    PP     +    R P  P P           +LA G 
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGP 611

Query: 660 PAAPLSRPAATM----VTNVVRPVSSTPVPIASKPF-PTSGRAEASPNDTAGARTEMGTG 714
           P  P   P++T+    +       +STP  +      P  G A + P D   A       
Sbjct: 612 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671

Query: 715 SRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPA 774
           SR P   PL        + +  A  P P    GP     G A    T      P    PA
Sbjct: 672 SRGPA-PPLAF------RGAPGAPLPWPP-ATGP-----GSADGLCTIYETEGPESATPA 718

Query: 775 PPAVQ-FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLP 833
           P A+    + G  GG   AG+GAGA S       LG L  GAL       Q   +   L 
Sbjct: 719 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL-------QASVVQHLLS 771

Query: 834 QQLQVAPAPAPAPGTKAAAPSG 855
           + L +A A   A G+    P G
Sbjct: 772 RTLLLAAAEGAAGGS-GGGPGG 792



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 100/432 (23%), Positives = 143/432 (33%), Gaps = 87/432 (20%)

Query: 1193 EAGASGRPGPAPRQP--LEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLP 1250
            +AGA+ R  PA R P  L P P            G P PP PP  P        +     
Sbjct: 9    KAGAAART-PAARAPGLLTPRP-----------PGSPRPP-PPVTPAALRVLGAAGAVGR 55

Query: 1251 PPAEERTSAKGPETMASKFP------SSSSDWRVPGQG--LENRGE-PPTPPSPAPAPAV 1301
             P  ER    G  T+    P      S+ +  R P        RGE  P   + +P P  
Sbjct: 56   KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115

Query: 1302 APGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAE 1361
            +PG +S ++     G    R  A  T  + K    P +    +   R  S          
Sbjct: 116  SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG--------- 166

Query: 1362 LPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTS-PKRKMRRRSSC 1420
                 P    PSP +   + +    +G  R          + P  PT  P++ +   S  
Sbjct: 167  -----PTPGTPSPAMARRSRAAGTEVGLPRPAPS------ARPRPPTEGPRKSVSSASEH 215

Query: 1421 SSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQD 1480
            S+   +P + +         R  + +      L     P SS  R+              
Sbjct: 216  STTEPSPAARRRPSAGGGLQRPASRS------LSSSATPLSSPARS-------------- 255

Query: 1481 HGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPP 1540
                PSA+ T    A      PS         + + K +QA  P +  P  +   P   P
Sbjct: 256  ---GPSARGTPRAPAH-----PS---------QPKPKGLQALRPPQVTPPRKDAAPALGP 298

Query: 1541 TGTAAAPAPTPSPAGGPD-----PTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPS 1595
              ++    P+PS A         P +P S S T Q A PLP  P S    P  +  P P 
Sbjct: 299  LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358

Query: 1596 PPPPGPSTAATG 1607
              PP  +T + G
Sbjct: 359  ATPPSQATTSLG 370



 Score = 39.7 bits (91), Expect = 0.024
 Identities = 40/123 (32%), Positives = 43/123 (34%), Gaps = 41/123 (33%)

Query: 1522 ATPTEQPPGAEAPLPVP------PPTGTAAAPAPTPSPA-------GGPDPTSPSS---- 1564
            A+PT Q P    P P P      P    A AP P P P+        GPD    SS    
Sbjct: 579  ASPTLQAP-RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 637

Query: 1565 --------DSGTAQAAPPLPPPP-----------ESGPGQP----GWEGAPQPSPPPPGP 1601
                    DSG    A   PPP              GP  P    G  GAP P PP  GP
Sbjct: 638  TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 697

Query: 1602 STA 1604
             +A
Sbjct: 698  GSA 700



 Score = 37.7 bits (86), Expect = 0.090
 Identities = 41/147 (27%), Positives = 63/147 (42%), Gaps = 17/147 (11%)

Query: 42  PFLAPSQP-----DPSVQPSEA--QQPASHPVASNQSKEPAESAAVAHERPPGGTGSADP 94
           P   PSQ       P++Q + +    P   P+A+   + P   A    + PP  +  A P
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP--SPPASP 415

Query: 95  ERPPGATCPESPGPGPPHPLGV--VESGKGPPPTTEEEAS-GPPGEPRLDSETESDHDDA 151
              P AT    P P  P+ L V  +++   PPP+   +A   PP  P + S + +    A
Sbjct: 416 PLSPLAT----PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSATPPSQA 470

Query: 152 FLSIMSPEIQLPLPPGKRRTQSLSALP 178
             S+ +P +Q+P  P      S SA P
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATP 497



 Score = 37.7 bits (86), Expect = 0.090
 Identities = 41/139 (29%), Positives = 53/139 (38%), Gaps = 13/139 (9%)

Query: 29  PRSVAVFPWHSL-VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPG 87
           P ++AV   H L  PF  P  P      S    P   P A+  S+ P   AA   + PP 
Sbjct: 428 PNALAV---HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 484

Query: 88  GTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESD 147
              S  P  P     P++P P    PL + +    PPP      + PP +  L S   S 
Sbjct: 485 PPASP-PMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPLQ-ALPSPPASF 538

Query: 148 HDDAFLSIMSPEIQLPLPP 166
              A     SP   LP+ P
Sbjct: 539 PGQA---PFSPSASLPMSP 554



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 35/136 (25%), Positives = 46/136 (33%), Gaps = 34/136 (25%)

Query: 46  PSQPDPS----------VQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE 95
           PSQP P             P +   PA  P++S+    P+ SAA+  + PP         
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP--------- 319

Query: 96  RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSI 155
                       P  PH   +      P P      S PP    L S   +    A  S+
Sbjct: 320 ----------TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369

Query: 156 MSPEIQ-----LPLPP 166
            SP +Q     LP PP
Sbjct: 370 GSPTLQATHSFLPSPP 385



 Score = 35.4 bits (80), Expect = 0.45
 Identities = 35/144 (24%), Positives = 44/144 (30%), Gaps = 22/144 (15%)

Query: 46  PSQPDPSVQPSEAQQPASHPVAS--NQSKEPAESAAVAHERPPGGTGSADPERPPGATCP 103
           PSQ  PS+     Q P S P +   + S  P   A      PP       P+ PP    P
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526

Query: 104 ----------ESPGPGPPHPLGVVESGK--GPPPTTE--------EEASGPPGEPRLDSE 143
                       PG  P  P   +       PPP           +    PP  P L + 
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586

Query: 144 TESDHDDAFLSIMSPEIQLPLPPG 167
                     S+  P + L L PG
Sbjct: 587 RRPPTPGPDTSVSGPRLTLALAPG 610



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 38/156 (24%), Positives = 51/156 (32%), Gaps = 35/156 (22%)

Query: 48  QPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTG-----------SADPER 96
           +P PS +P    +     V+S       E +  A  RP  G G           SA P  
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250

Query: 97  PPGATCPESPG-------PGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHD 149
            P  + P + G       P  P P G+      PP  T      PP           D  
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGL--QALRPPQVT------PP---------RKDAA 293

Query: 150 DAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSS 185
            A   + S  +  P P    ++Q+   LP    SSS
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score =  138 bits (347), Expect = 5e-32
 Identities = 212/773 (27%), Positives = 272/773 (35%), Gaps = 152/773 (19%)

Query: 642  GGGARVPSAPAPSLAYGAPAA-----PLSRPAATMVTNVVRPVSSTPVP-----IASKPF 691
            G  AR P+A AP L    P       P   PAA  V      V   P+      I     
Sbjct: 11   GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 692  PTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLG 751
            P S    A P  T+      G G R P                A  TSP P    G   G
Sbjct: 71   PESA-PRAGPTRTSRPPAS-GRGERAP---------------PAKNTSPGPVSSPGRASG 113

Query: 752  TVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQG-APGGGTTAGSGAGAGSGPNGPVPLGI 810
            T    P     L +           A + +A+G A      +   AGA    +GP P G 
Sbjct: 114  TTRPGPLGQKGLRIS----------AEETVARGKATEAPKRSALSAGARRDTSGPTP-GT 162

Query: 811  LQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPS----------GPAPTT 860
              P A+ +       +  LP      + AP+  P P T+    S           P+P  
Sbjct: 163  PSP-AMARRSRAAGTEVGLP------RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 215

Query: 861  SIRFTLPPGTSTNGKVLAATAPTP------------GIPILQSVPSAPPPKA-QSVSPVQ 907
              R +   G         +++ TP            G P   + PS P PK  Q++ P Q
Sbjct: 216  RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 275

Query: 908  APPPGGSAQLLPGKVLV-PLAAPSMSVRGGGAGQPL--PLVSPPFSVPVQNGAQPPSKII 964
              PP   A    G +   PLA PS S     +  P    L SPP + P Q      S  +
Sbjct: 276  VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335

Query: 965  QLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASS 1024
            Q T   + +P     PLSP   P P + P   L P              A P  + PAS 
Sbjct: 336  QATHSFLPSP-----PLSPLATPPPQAPPALALPPLQ------------APP--SPPASP 376

Query: 1025 QAGTVTSYGPTSSVALGFTSL-GPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSP--QLP 1081
                + +  P +  AL    L  P  P    P+    QAP   P    VSP  +P  Q P
Sbjct: 377  PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV----QAPFSPPASPPVSPSATPPSQAP 432

Query: 1082 PACAAPGGPVITAFYSGSPAPTSSAPLAQ----PSQAPPSLVYTVATSTTPPAATILPKG 1137
            P+ AAP   V        P+P +S P++     P QAPP L         PP     P+ 
Sbjct: 433  PSLAAPPLQV-------PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP-----PQA 480

Query: 1138 PPAPAT----ATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFE 1193
            PPA AT    A P+P + FP     S + SL       P P+AP  + A +  +P     
Sbjct: 481  PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP----P 536

Query: 1194 AGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPT-----ARSSPP 1248
            +  +     APR+P  PGP    + P   L   P PP PP    + T +       SS  
Sbjct: 537  SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 596

Query: 1249 LPPPAEERTSAKGPETMASKFPSSSSD--------W-RVPGQGLENRGEP--PTPPSPAP 1297
               P E R    GPE  A+  P   ++        W R P   L  RG P  P P  PA 
Sbjct: 597  TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656

Query: 1298 APAVAPG--------GSSESSSGRAAGD------TPERKEAAGTGKKVKVRPP 1336
             P  A G        G   ++    A D      T   K AAG G     R P
Sbjct: 657  GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709



 Score =  127 bits (319), Expect = 9e-29
 Identities = 176/729 (24%), Positives = 252/729 (34%), Gaps = 92/729 (12%)

Query: 510  LDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAG 569
            L P PPG P PP        +     A+        A  +  +G  T        G T  
Sbjct: 25   LTPRPPGSPRPPPPVTPA--ALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT 82

Query: 570  PLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP------SVIAAPPSG 623
              RPP  G G  A P+K T   P+         P    G   PGP       + A     
Sbjct: 83   S-RPPASGRGERAPPAKNTSPGPVSS-------PGRASGTTRPGPLGQKGLRISAEETVA 134

Query: 624  GGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTP 683
             G   +     P +     G  R  S P P    G P+  ++R +    T V  P    P
Sbjct: 135  RGKATEA----PKRSALSAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP---RP 183

Query: 684  VPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPH 743
             P A    PT G  ++  + +  + TE    +R    +  G+    S   S++AT  +  
Sbjct: 184  APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243

Query: 744  LVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPN 803
              +GP      +APA  +           P P  +Q +    P   T     A    GP 
Sbjct: 244  ARSGPSARGTPRAPAHPSQ----------PKPKGLQALR---PPQVTPPRKDAAPALGPL 290

Query: 804  GPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIR 863
               PL    P A              P+ P  LQ  P+P   P ++A    G     +  
Sbjct: 291  SSSPLATPSPSAPPS-----------PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 339

Query: 864  FTLP-PGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKV 922
              LP P  S          P   +P LQ+ PS  PP +  +SP+  P P     L    +
Sbjct: 340  SFLPSPPLSPLATPPPQAPPALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLL 397

Query: 923  LVPLAAPSMSVRGGGAGQPLPLV----SPPFSVPVQNGAQPPSKI---IQLTPVPVSTPS 975
              P + P           P P V    SPP S PV   A PPS+    +   P+ V    
Sbjct: 398  QAPFSPP-----------PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446

Query: 976  GLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALP----LGTSPASSQAGTVTS 1031
               PP+SP+  P P + P     P        Q+    A P    L + PAS        
Sbjct: 447  PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA--P 504

Query: 1032 YGPTSSVALGFTSLGP--SGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGG 1089
            + P++S+ +   +  P  + P    PLL    +P  +P        P+P   P  +  G 
Sbjct: 505  FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG--PDTSVSGP 562

Query: 1090 PVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPT 1149
             +  A   G P P S +P +  S  P    ++ + ++TP        GP   A A+P P 
Sbjct: 563  RLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621

Query: 1150 SPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS------IPVGSFEAGASGRPGPA 1203
            +   +    + +     P A R +P AP     A           +   E   S  P P 
Sbjct: 622  AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681

Query: 1204 PRQPLEPGP 1212
                L+PGP
Sbjct: 682  ---ALDPGP 687



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 195/824 (23%), Positives = 279/824 (33%), Gaps = 197/824 (23%)

Query: 383  PASYSGPK-PSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERM 441
            PAS  G + P  +  +PGP ++PG        G       R S  +  A    T   +R 
Sbjct: 86   PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145

Query: 442  VICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRS 501
             +                            +     D+SG  P    G      +   R+
Sbjct: 146  AL----------------------------SAGARRDTSGPTP----GTPSPAMARRSRA 173

Query: 502  SFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQE 561
            + T    P  P P   P PP    +   S  S+S  S    S +A    S G G  +   
Sbjct: 174  AGTEVGLP-RPAPSARPRPPTEGPR--KSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 230

Query: 562  SGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPP 621
                S+A PL         PA    + R  P  PA   + +P+ +  L PP         
Sbjct: 231  RSLSSSATPL-------SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--------- 274

Query: 622  SGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSS 681
                      V PP K+     G  + S+P  + +  AP +P + P+          + +
Sbjct: 275  ---------QVTPPRKDAAPALGP-LSSSPLATPSPSAPPSPSAPPS----------LQT 314

Query: 682  TPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP- 740
             P P A+ P        +    + G+ T   T S +P           S   S  AT P 
Sbjct: 315  LPSPPATPP--------SQATTSLGSPTLQATHSFLP-----------SPPLSPLATPPP 355

Query: 741  -APHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAG 799
             AP  +A P L      PA+     + TP   AP   AV  +              A   
Sbjct: 356  QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-------------APFS 402

Query: 800  SGPNGPVPLGILQPGALGKAGGITQVQYILPTL-PQQLQVAPAPAPAPGTKAAA---PSG 855
              P+ PV      P +   +   T      P+L    LQV P+P  +P    +A   P  
Sbjct: 403  PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462

Query: 856  PAPTTS--IRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAP-PPG 912
            P P  +  ++   PP             P    P LQ++PS P     +  P QAP  P 
Sbjct: 463  PPPLAAPPLQLAKPP---------PQAPPALATPPLQALPSPP-----ASFPGQAPFSPS 508

Query: 913  GSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLV--SPPFSVPVQNGAQPPSKIIQLTPVP 970
             S  + P     P A P ++        PL  V  SPP S  +Q   +PP      TP P
Sbjct: 509  ASLPMSPLATPPPQAPPVLAA-------PLLQVPPSPPASPTLQAPRRPP------TPGP 555

Query: 971  VSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVT 1030
             ++ SG  P L+ A  PGP   P +                    P  T      AG  +
Sbjct: 556  DTSVSG--PRLTLALAPGPPPPPSR-------------------SPSSTLSGPDLAGHSS 594

Query: 1031 SYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGP 1090
            S   T     G+ S GP G A   P      A L A      S  P+P L     APG P
Sbjct: 595  SATSTPEELRGYDS-GPEGGAAASP---PPDAELAACHPAAWSRGPAPPL-AFRGAPGAP 649

Query: 1091 VITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTS 1150
            +        P P ++ P +         + T+  +  P +AT      PAP    P P+ 
Sbjct: 650  L--------PWPPATGPGSADG------LCTIYETEGPESAT------PAPGALDPGPS- 688

Query: 1151 PFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEA 1194
                 T+G    +     A   SPK     +A +  +P+G+ +A
Sbjct: 689  ---PGTSGGKAAAGAGAGASSRSPK-----QARLGELPLGALQA 724



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 137/560 (24%), Positives = 183/560 (32%), Gaps = 141/560 (25%)

Query: 1066 APGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATS 1125
            APG +   P  SP+ PP        V+     G+       PLA+ +          +  
Sbjct: 21   APGLLTPRPPGSPRPPPPVTPAALRVL-----GAAGAVGRKPLAERAGGIGGATIPESAP 75

Query: 1126 TTPPAATILPKGPPAPATATPAP-TSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAI 1184
               P  T  P        A PA  TSP P ++ G       A    RP P   + ++   
Sbjct: 76   RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGR------ASGTTRPGPLGQKGLR--- 126

Query: 1185 ASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTAR 1244
                + + E  A G+   AP++       R  T+        PTP  P P     +  A 
Sbjct: 127  ----ISAEETVARGKATEAPKRSALSAGARRDTSG-------PTPGTPSPAMARRSRAAG 175

Query: 1245 SSPPLP---PPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAV 1301
            +   LP   P A  R   +GP    S     S+                T PSPA     
Sbjct: 176  TEVGLPRPAPSARPRPPTEGPRKSVSSASEHST----------------TEPSPAARRRP 219

Query: 1302 APGGSSESSSGRAAGD--TPERKEA-AGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEER 1358
            + GG  +  + R+     TP    A +G   +   R P                   + +
Sbjct: 220  SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS---------------QPK 264

Query: 1359 FAELPEFRPEEVLP-----SPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRK 1413
               L   RP +V P     +P L  L++SP A            T   SAP  P++P   
Sbjct: 265  PKGLQALRPPQVTPPRKDAAPALGPLSSSPLA------------TPSPSAPPSPSAPPSL 312

Query: 1414 MRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRAL 1473
                 +  S P TP S               +A   LG          +L+ T       
Sbjct: 313  Q----TLPSPPATPPS---------------QATTSLGS--------PTLQAT------- 338

Query: 1474 VMQLFQDHGFFPSAQ----ATAAFQARYADIFPSKVCLQLKIRE-VRQKIMQAATPTEQP 1528
                   H F PS      AT   QA  A   P    LQ          +   ATP+ Q 
Sbjct: 339  -------HSFLPSPPLSPLATPPPQAPPALALPP---LQAPPSPPASPPLSPLATPSPQA 388

Query: 1529 PGA------EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPL---PPPP 1579
            P A      +AP   PP     A  +P  SP   P  T PS  +  + AAPPL   P PP
Sbjct: 389  PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ-APPSLAAPPLQVPPSPP 447

Query: 1580 ESGPGQPGWEGAPQPSPPPP 1599
             S P  P     P P  PPP
Sbjct: 448  ASPPMSP--SATPPPQAPPP 465



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 103/382 (26%), Positives = 135/382 (35%), Gaps = 56/382 (14%)

Query: 496 SPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSG 555
           SP +++ F+   PP  P       PP         AP S A+ P     S   S  +   
Sbjct: 406 SPPVQAPFS---PPASPPVSPSATPP-------SQAPPSLAAPPLQVPPSPPASPPMSPS 455

Query: 556 TFKAQESGQGSTAGPLR--PPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPG 613
                ++     A PL+   PPP A  PA  +   + LP  PA+F  + P S     P  
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMS 514

Query: 614 PSVIA---APPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAP-----------SLAYGA 659
           P       APP     +LQ    PP     +    R P  P P           +LA G 
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGP 572

Query: 660 PAAPLSRPAATM----VTNVVRPVSSTPVPIASKPF-PTSGRAEASPNDTAGARTEMGTG 714
           P  P   P++T+    +       +STP  +      P  G A + P D   A       
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632

Query: 715 SRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPA 774
           SR P   PL        + +  A  P P    GP     G A    T      P    PA
Sbjct: 633 SRGPA-PPLAF------RGAPGAPLPWPP-ATGP-----GSADGLCTIYETEGPESATPA 679

Query: 775 PPAVQ-FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLP 833
           P A+    + G  GG   AG+GAGA S       LG L  GAL       Q   +   L 
Sbjct: 680 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL-------QASVVQHLLS 732

Query: 834 QQLQVAPAPAPAPGTKAAAPSG 855
           + L +A A   A G+    P G
Sbjct: 733 RTLLLAAAEGAAGGS-GGGPGG 753



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 94/326 (28%), Positives = 116/326 (35%), Gaps = 62/326 (19%)

Query: 508 PPLDPEPP--GPPDPPVAFGKGYGSAP-SSSASSPASSSASAATSFS--LGSGTFKAQES 562
           PP    PP    P PP +F    G AP S SAS P S  A+        L +   +   S
Sbjct: 481 PPALATPPLQALPSPPASFP---GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 537

Query: 563 GQGSTA--GPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPES-VGGLEPPGPSVIAA 619
              S     P RPP PG     +  + T  L   P     + P S + G +  G S  A 
Sbjct: 538 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597

Query: 620 P-----------PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAY-GAPAAPLSRP 667
                       P GG         PP+ E      A     PAP LA+ GAP APL  P
Sbjct: 598 STPEELRGYDSGPEGGAAASP----PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653

Query: 668 AAT---------MVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVP 718
            AT          +     P S+TP P A  P P+ G +       AGA    G  SR P
Sbjct: 654 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA----GASSRSP 709

Query: 719 GGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAV 778
             + LG   +      A   S   HL++  LL    +  A  +    G PG         
Sbjct: 710 KQARLGELPL-----GALQASVVQHLLSRTLLLAAAEGAAGGSG---GGPG--------- 752

Query: 779 QFIAQGAPGGGTTAGSGAGAGSGPNG 804
                GA GGG T G+ A       G
Sbjct: 753 -----GAEGGGVTGGARAALSDAELG 773



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 158/693 (22%), Positives = 215/693 (31%), Gaps = 142/693 (20%)

Query: 973  TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSY 1032
            TP+   P L     PG    P  V  P++ R+       G A  +G  P + +AG +   
Sbjct: 16   TPAARAPGLLTPRPPGSPRPPPPVT-PAALRVL------GAAGAVGRKPLAERAGGIGGA 68

Query: 1033 ---------GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSP----- 1078
                     GPT +     +  G   P    P  +    P+ +PG+   +  P P     
Sbjct: 69   TIPESAPRAGPTRTSRPPASGRGERAP----PAKNTSPGPVSSPGRASGTTRPGPLGQKG 124

Query: 1079 ------QLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAAT 1132
                  +      A   P  +A  +G+   TS      PS A         T    P   
Sbjct: 125  LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184

Query: 1133 ILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSF 1192
              P   P P T    P     SA+  S T          PSP A ++  A          
Sbjct: 185  --PSARPRPPTE--GPRKSVSSASEHSTT---------EPSPAARRRPSAG--------- 222

Query: 1193 EAGASGRPGPAPRQPLEPG-PVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPP 1251
                 G   PA R       P+  P        G P  PA P  P+     A   P + P
Sbjct: 223  ----GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278

Query: 1252 PAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSS 1311
            P ++   A GP         SSS    P             PS  P+P+  P   +  S 
Sbjct: 279  PRKDAAPALGP--------LSSSPLATPS------------PSAPPSPSAPPSLQTLPSP 318

Query: 1312 GRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEV-----DFEERFAELPEFR 1366
                  TP  +     G       P L+ T   + +  LS +           A  P   
Sbjct: 319  PA----TPPSQATTSLGS------PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 368

Query: 1367 PEEVLPSPTLQSLAT-SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPN 1425
            P     SP L  LAT SP+A           +  L  AP  P          S  +S P 
Sbjct: 369  PPSPPASPPLSPLATPSPQA-------PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 421

Query: 1426 TPKS---AKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHG 1482
            +P +   ++    +         +      +     P       L    A  +QL +   
Sbjct: 422  SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL---AAPPLQLAKPPP 478

Query: 1483 FFPSAQATAAFQARYAD--IFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPL----P 1536
              P A AT   QA  +    FP +             +  A  P + PP   APL    P
Sbjct: 479  QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPP 536

Query: 1537 VPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQP---------- 1586
             PP + T  AP   P+P  GPD TS S    T   AP  PPPP   P             
Sbjct: 537  SPPASPTLQAPRRPPTP--GPD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 593

Query: 1587 -----------GWEGAPQ---PSPPPPGPSTAA 1605
                       G++  P+    + PPP    AA
Sbjct: 594  SSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626



 Score = 39.7 bits (91), Expect = 0.024
 Identities = 40/123 (32%), Positives = 43/123 (34%), Gaps = 41/123 (33%)

Query: 1522 ATPTEQPPGAEAPLPVP------PPTGTAAAPAPTPSPA-------GGPDPTSPSS---- 1564
            A+PT Q P    P P P      P    A AP P P P+        GPD    SS    
Sbjct: 540  ASPTLQAP-RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 598

Query: 1565 --------DSGTAQAAPPLPPPP-----------ESGPGQP----GWEGAPQPSPPPPGP 1601
                    DSG    A   PPP              GP  P    G  GAP P PP  GP
Sbjct: 599  TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 658

Query: 1602 STA 1604
             +A
Sbjct: 659  GSA 661



 Score = 38.5 bits (88), Expect = 0.053
 Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 15/108 (13%)

Query: 1512 REVRQKIMQAATPTEQP----------PGAEAPLPVPPPTGTAAAPAP--TPSPAGGPDP 1559
            R   + +  +ATP   P          P A A    P P G  A   P  TP        
Sbjct: 227  RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 286

Query: 1560 TSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATG 1607
              P S S  A  +P  PP P +    P  +  P P   PP  +T + G
Sbjct: 287  LGPLSSSPLATPSPSAPPSPSA---PPSLQTLPSPPATPPSQATTSLG 331



 Score = 38.5 bits (88), Expect = 0.053
 Identities = 48/188 (25%), Positives = 72/188 (38%), Gaps = 26/188 (13%)

Query: 10  PASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQ---------- 59
           P    A+  LG    + +   S +  P  S  P L      P+  PS+A           
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337

Query: 60  ------QPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHP 113
                  P   P+A+   + P   A    + PP  +  A P   P AT    P P  P+ 
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPP--SPPASPPLSPLAT----PSPQAPNA 391

Query: 114 LGV--VESGKGPPPTTEEEAS-GPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRR 170
           L V  +++   PPP+   +A   PP  P + S + +    A  S+ +P +Q+P  P    
Sbjct: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSATPPSQAPPSLAAPPLQVPPSPPASP 450

Query: 171 TQSLSALP 178
             S SA P
Sbjct: 451 PMSPSATP 458



 Score = 37.7 bits (86), Expect = 0.090
 Identities = 41/139 (29%), Positives = 53/139 (38%), Gaps = 13/139 (9%)

Query: 29  PRSVAVFPWHSL-VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPG 87
           P ++AV   H L  PF  P  P      S    P   P A+  S+ P   AA   + PP 
Sbjct: 389 PNALAV---HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445

Query: 88  GTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESD 147
              S  P  P     P++P P    PL + +    PPP      + PP +  L S   S 
Sbjct: 446 PPASP-PMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPLQ-ALPSPPASF 499

Query: 148 HDDAFLSIMSPEIQLPLPP 166
              A     SP   LP+ P
Sbjct: 500 PGQA---PFSPSASLPMSP 515



 Score = 35.4 bits (80), Expect = 0.45
 Identities = 35/144 (24%), Positives = 44/144 (30%), Gaps = 22/144 (15%)

Query: 46  PSQPDPSVQPSEAQQPASHPVAS--NQSKEPAESAAVAHERPPGGTGSADPERPPGATCP 103
           PSQ  PS+     Q P S P +   + S  P   A      PP       P+ PP    P
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487

Query: 104 ----------ESPGPGPPHPLGVVESGK--GPPPTTE--------EEASGPPGEPRLDSE 143
                       PG  P  P   +       PPP           +    PP  P L + 
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 547

Query: 144 TESDHDDAFLSIMSPEIQLPLPPG 167
                     S+  P + L L PG
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPG 571



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 40/165 (24%), Positives = 52/165 (31%), Gaps = 46/165 (27%)

Query: 48  QPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTG-----------SADPER 96
           +P PS +P    +     V+S       E +  A  RP  G G           SA P  
Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241

Query: 97  PPGATCPESPGP--GPPHP--------------------------LGVVESG--KGPPPT 126
            P  + P + G    P HP                          LG + S     P P+
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301

Query: 127 TEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQ-----LPLPP 166
                S PP    L S   +    A  S+ SP +Q     LP PP
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 22/93 (23%), Positives = 28/93 (30%), Gaps = 7/93 (7%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSG-------TAQAAPPL 1575
            T T +PP +      PP   T+  P  +P  A G     P    G       T       
Sbjct: 80   TRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139

Query: 1576 PPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608
              P  S            P+P  P P+ A   R
Sbjct: 140  EAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 172


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score =  129 bits (324), Expect = 2e-29
 Identities = 200/790 (25%), Positives = 295/790 (37%), Gaps = 130/790 (16%)

Query: 570  PLRPPP-PGAGGPATPSKATRFLPMD-PATFRRKRPESVGGLEPPGPSVIAAPPSGGGNI 627
            P+RPPP P      TP    + LP     +     P  +    PPGP ++       G++
Sbjct: 1023 PVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSL 1082

Query: 628  LQTLVLP------------PNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRP-------- 667
             Q L  P            P    +    A V  +PAP     +   PL+ P        
Sbjct: 1083 PQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPA 1142

Query: 668  AATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGV-- 725
            AAT  +      ++T VP    P P   R   SP+  A          R+P G  + +  
Sbjct: 1143 AATTTSTTTATATTTAVPA---PTPAPQRLILSPDMQA----------RLPSGEVVSIGQ 1189

Query: 726  --SLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQ 783
              SL      +A  + P    + G  L   G   A V  L VG P       P  + +  
Sbjct: 1190 LASLAQRPVANAGGSKPLTFQIQGNKLTLTG---AQVRQLAVGQPR------PLQRNVVH 1240

Query: 784  GAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPA 843
                GG                      Q   + +   +  +Q + PT P    V+  P+
Sbjct: 1241 LVSAGG----------------------QHHLISQPAHVALIQAVAPT-PGPTPVSVLPS 1277

Query: 844  PAPGTKAAAPSGPAPTTSIRFTLPPGTSTNG--KVLAATAPTPGIPILQSVPSAPPPKAQ 901
              P T   AP+G +   +     P   +  G  K++   AP  G+  +  +  AP P + 
Sbjct: 1278 STPST-TPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSS 1336

Query: 902  SVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPS 961
             +  V  P P     L PG++  P          G A  P+P  +P    P+      PS
Sbjct: 1337 GLPAVLNPRP----TLTPGRLPTPTL--------GTARAPMP--TPTLVRPLLKLVHSPS 1382

Query: 962  KIIQLTPVPVSTPSGLVPPLS-PATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTS 1020
              +  +  P + P  +  PL  P++LPGP S P  +  P+S+ +    S+   ++PL +S
Sbjct: 1383 PEVSAS-APGAAPLTISSPLHVPSSLPGPASSPMPI--PNSSPLASPVSSTV-SVPLSSS 1438

Query: 1021 PASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQL 1080
               S   T+ +    +S  L      P   +   P L     P LAP  V  +P P P L
Sbjct: 1439 LPISVPTTLPA---PASAPLTIPISAPLTVSASGPALLTSVTPPLAP-VVPAAPGP-PSL 1493

Query: 1081 PPACAAPGGPVITAFYSGSPAPTSSAP------LAQPSQAPPSLVYTVATSTTPPAATIL 1134
             P+ A+P    +T   + +P+ +SS        LA  S   P L  TVA + +P      
Sbjct: 1494 APSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPAS 1553

Query: 1135 PKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPK----APQKVKAAIASIPVG 1190
                P P+   PAP      A A S + +L  P A   +P+    AP      +A +PV 
Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPA-PPLAPLPVL 1612

Query: 1191 SFEAGASGRPGPAPRQPLEPGPVREPTA-PESELEGQPTPPAPPP-LPETWTPTARSSP- 1247
            +   GA+    P       P PV  P++ P + L      PAP P L  + T T   +P 
Sbjct: 1613 APSPGAA----PVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPV 1668

Query: 1248 --PLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTP-----------PS 1294
              PLP PA  +T A  P    +   SS S     G G   +G  PT            P+
Sbjct: 1669 PSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTG-NPQGPFPTQTLSLTPASSLVPT 1727

Query: 1295 PAPAPAVAPG 1304
            PA   ++APG
Sbjct: 1728 PAQTLSLAPG 1737



 Score =  126 bits (316), Expect = 2e-28
 Identities = 235/897 (26%), Positives = 318/897 (35%), Gaps = 189/897 (21%)

Query: 507  RPPLDPE-----PPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSL--GSGTF-K 558
            RPP  PE      PGP    +       ++P+     PAS          L   SG+  +
Sbjct: 1025 RPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQ 1084

Query: 559  AQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIA 618
               S  G  +G  RPP P      TP    R  P                          
Sbjct: 1085 VLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSP-------------------------- 1118

Query: 619  APPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRP 678
            APP G  ++L+ L +PP                     Y  P A     AAT  +     
Sbjct: 1119 APPPGSSSLLKPLTVPP--------------------GYTFPPA-----AATTTSTTTAT 1153

Query: 679  VSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGV----SLVYSDKKS 734
             ++T VP    P P   R   SP+  A          R+P G  + +    SL      +
Sbjct: 1154 ATTTAVP---APTPAPQRLILSPDMQA----------RLPSGEVVSIGQLASLAQRPVAN 1200

Query: 735  AAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTP----------------GYGAPAPPAV 778
            A  + P    + G  L   G   A V  L VG P                 +    P  V
Sbjct: 1201 AGGSKPLTFQIQGNKLTLTG---AQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHV 1257

Query: 779  QFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGK-----AGGITQVQYILPTLP 833
              I   AP  G T  S   + +    P P G+  P A  +           V+ ++   P
Sbjct: 1258 ALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAP 1317

Query: 834  QQ-LQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPG---TSTNGKVLAATAPTPGI--P 887
            +  L   P  APAP   +   SG     + R TL PG   T T G    A  PTP +  P
Sbjct: 1318 RDGLTPVPPLAPAPRPPS---SGLPAVLNPRPTLTPGRLPTPTLG-TARAPMPTPTLVRP 1373

Query: 888  ILQSVPSAPPPKAQSV---------SPVQAPP--PGGSAQLLPGKVLVPLAAPSMSVRGG 936
            +L+ V S  P  + S          SP+  P   PG ++  +P     PLA+P  S    
Sbjct: 1374 LLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSV 1433

Query: 937  GAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTP-----SGLVPPLSPA--TLPGP 989
                 LP +S P ++P    A  P  I    P+ VS       + + PPL+P     PGP
Sbjct: 1434 PLSSSLP-ISVPTTLPAP--ASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGP 1490

Query: 990  TSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQA---GTVTSYGPTSSVALGFTS-L 1045
             S       PS++ +T         L L T+P+ S +   G      PTSS   G  S +
Sbjct: 1491 PSLAPSGASPSASALT---------LGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTV 1541

Query: 1046 GPS-------GPAFVQPLLSA-----GQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVIT 1093
             P+         A   P  SA      QA LLAP       + +P  P   AAP     T
Sbjct: 1542 APACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP--MAAPQ----T 1595

Query: 1094 AFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPT-SPF 1152
            A  + SPAP   APL  P  AP      V  S+  P   + P   P  + A+ +P  +P 
Sbjct: 1596 AILAPSPAP-PLAPL--PVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPT 1652

Query: 1153 PSATAGSMTYSLVAP-KAQRPSPKAPQKVKAAIA-------SIPVGSFEAGASGRPGPAP 1204
            P     S    L AP  +  PSP + Q +  A A       S P  +   G     GP P
Sbjct: 1653 PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFP 1712

Query: 1205 RQPLEPGPVRE--PTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGP 1262
             Q L   P     PT P   L   P PP  P    T T +   +PPL P +    +    
Sbjct: 1713 TQTLSLTPASSLVPT-PAQTLSLAPGPPLGP----TQTLSLAPAPPLAPASPVGPAPAHT 1767

Query: 1263 ETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTP 1319
             T+A   P+SSS   +    ++         SPAP P + P  +   +   A+  +P
Sbjct: 1768 LTLA---PASSSASLLAPASVQT-----LTLSPAPVPTLGPAAAQTLALAPASTQSP 1816



 Score =  112 bits (280), Expect = 3e-24
 Identities = 196/683 (28%), Positives = 253/683 (37%), Gaps = 104/683 (15%)

Query: 603  PESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGG-GARVPSAPAPSLAYGAPA 661
            P  V  L    PS   AP +G    L    +PP      G     V  AP   L    P 
Sbjct: 1269 PTPVSVLPSSTPSTTPAP-TGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPL 1327

Query: 662  APLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAG-ARTEMGTGSRVPGG 720
            AP  RP          P S  P  +  +P  T GR    P  T G AR  M T + V   
Sbjct: 1328 APAPRP----------PSSGLPAVLNPRPTLTPGRL---PTPTLGTARAPMPTPTLV--- 1371

Query: 721  SPLGVSLVYSDKKSAAATSP--APHLVAGPL-----LGTVGKAPATVTNLL-VGTPGYGA 772
             PL + LV+S     +A++P  AP  ++ PL     L     +P  + N   + +P    
Sbjct: 1372 RPL-LKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSST 1430

Query: 773  PAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTL 832
             + P    +    P   TT  + A A      P+ + I  P  +  +G         P  
Sbjct: 1431 VSVPLSSSLPISVP---TTLPAPASA------PLTIPISAPLTVSASGPALLTSVTPPLA 1481

Query: 833  PQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSV 892
            P    V PA   APG  + APSG +P+ S   TL   T+ +     +++ TPG P+L + 
Sbjct: 1482 P----VVPA---APGPPSLAPSGASPSASA-LTLGLATAPS----LSSSQTPGHPLLLAP 1529

Query: 893  PSAPPPKAQS-VSPVQAP---PPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPP 948
             S+  P   S V+P  +P   P    A   P       A  S+      A Q L     P
Sbjct: 1530 TSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP 1589

Query: 949  FSVPVQNGAQPPSKIIQLTPVPVSTPS-GLVPPLSPATLPGPTSQPQKVLLPSSTRITYV 1007
             + P Q     PS    L P+PV  PS G  P L+ +  P P      V+ PSST  T +
Sbjct: 1590 MAAP-QTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVP------VMAPSSTPGTSL 1642

Query: 1008 QSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAP 1067
             SA     P      SS    + +  P+           PS PA  Q L     AP LAP
Sbjct: 1643 ASASPVPAPTPVLAPSSTQTMLPAPVPSPL---------PS-PASTQTL---ALAPALAP 1689

Query: 1068 GQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPA----PTSSAPLAQPSQAPPSLVYTVA 1123
               G SP  S  L      P GP  T   S +PA    PT +  L+     P     T++
Sbjct: 1690 TLGGSSP--SQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLS 1747

Query: 1124 TSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPS--PKAPQKVK 1181
             +  PP A   P GP    T T AP S   S  A +   +L    A  P+  P A Q + 
Sbjct: 1748 LAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLA 1807

Query: 1182 AAIASI--PVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETW 1239
             A AS   P     +      G AP           P    S L        P    E  
Sbjct: 1808 LAPASTQSPASQASSLVVSASGAAPL----------PVTMVSRL--------PVSKDEPD 1849

Query: 1240 TPTARSSPPLPPPAEERTSAKGP 1262
            T T RS PP PP     TS  GP
Sbjct: 1850 TLTLRSGPPSPP--STATSFGGP 1870



 Score =  109 bits (272), Expect = 2e-23
 Identities = 196/731 (26%), Positives = 262/731 (35%), Gaps = 142/731 (19%)

Query: 529  GSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTA-----------GPLRPPPPG 577
            G  P S   S   S+  A T  SL     +   +   +T              L P PP 
Sbjct: 1268 GPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPL 1327

Query: 578  AGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNK 637
            A  P  PS         PA    +   + G L  P      AP         TLV P  K
Sbjct: 1328 APAPRPPSSGL------PAVLNPRPTLTPGRLPTPTLGTARAPMP-----TPTLVRPLLK 1376

Query: 638  EEQEGGGARVPSAPAPSLAYGAP-AAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGR 696
                     +  +P+P ++  AP AAPL+      +++ +   SS P P AS P P    
Sbjct: 1377 ---------LVHSPSPEVSASAPGAAPLT------ISSPLHVPSSLPGP-ASSPMPI--- 1417

Query: 697  AEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKA 756
                PN +  A     T S VP  S L +S+          T PAP   + PL   +  A
Sbjct: 1418 ----PNSSPLASPVSSTVS-VPLSSSLPISV--------PTTLPAP--ASAPLTIPIS-A 1461

Query: 757  PATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGAL 816
            P TV+      P       P +  +   APG  + A SGA   +     + LG+    +L
Sbjct: 1462 PLTVS---ASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASA---LTLGLATAPSL 1515

Query: 817  GKAGGITQVQYILPTLPQ----QLQVAPAPAPA--PGTKAAAP--SGPAPTTSIRFTLPP 868
              +        + PT          VAPA +P   P +  A+P  S P P  +    L P
Sbjct: 1516 SSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAP 1575

Query: 869  GTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAA 928
             +S +  +    AP          PS  PP A    PV AP PG +  L   +  VP+ A
Sbjct: 1576 ASSASQALATPLAPMAAPQTAILAPSPAPPLAPL--PVLAPSPGAAPVLASSQTPVPVMA 1633

Query: 929  PSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPG 988
            PS +                          P + +   +PVP  TP  L P  +   LP 
Sbjct: 1634 PSST--------------------------PGTSLASASPVPAPTPV-LAPSSTQTMLPA 1666

Query: 989  PTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASS--QAGTVTSYGPTSSVALGFTSLG 1046
            P   P    LPS      +  A   A  LG S  S     GT    GP  +  L  T   
Sbjct: 1667 PVPSP----LPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPAS 1722

Query: 1047 PSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSA 1106
               P   Q L S    P L P Q  +S  P+P L PA  +P GP      + +PA +S++
Sbjct: 1723 SLVPTPAQTL-SLAPGPPLGPTQT-LSLAPAPPLAPA--SPVGPAPAHTLTLAPASSSAS 1778

Query: 1107 PLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTS-PFPSATAGSMTYSLV 1165
             LA      P+ V T+  S  P    +   GP A  T   AP S   P++ A S+  S  
Sbjct: 1779 LLA------PASVQTLTLSPAP----VPTLGPAAAQTLALAPASTQSPASQASSLVVS-- 1826

Query: 1166 APKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEG 1225
                   S  AP  V   ++ +PV   E              L  GP   P+   S   G
Sbjct: 1827 ------ASGAAPLPV-TMVSRLPVSKDEPDT---------LTLRSGPPSPPSTATS--FG 1868

Query: 1226 QPTPPAPPPLP 1236
             P P   PP P
Sbjct: 1869 GPRPRRQPPPP 1879



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 142/577 (24%), Positives = 203/577 (35%), Gaps = 119/577 (20%)

Query: 497  PVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGT 556
            P + +S T    P+ P  PGPP            APS ++ S ++ +   AT+ SL S  
Sbjct: 1470 PALLTSVTPPLAPVVPAAPGPP----------SLAPSGASPSASALTLGLATAPSLSS-- 1517

Query: 557  FKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSV 616
              +Q  G      P     PG      P+ +   +P          P        P  + 
Sbjct: 1518 --SQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALA----SPFPSAPNPAPAQAS 1571

Query: 617  IAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVV 676
            + AP S     L T + P    +     A +  +PAP      P APL   A +     V
Sbjct: 1572 LLAPASSASQALATPLAPMAAPQT----AILAPSPAP------PLAPLPVLAPSPGAAPV 1621

Query: 677  RPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAA 736
               S TPVP+             +P+ T G  T + + S VP  +P+          S  
Sbjct: 1622 LASSQTPVPV------------MAPSSTPG--TSLASASPVPAPTPV------LAPSSTQ 1661

Query: 737  ATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGA 796
               PAP  V  PL      +PA+   L        A AP     +   +P    + G+G 
Sbjct: 1662 TMLPAP--VPSPL-----PSPASTQTL--------ALAPALAPTLGGSSPSQTLSLGTG- 1705

Query: 797  GAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAP----------APAP 846
                 P GP P   L          +T    ++PT  Q L +AP P          APAP
Sbjct: 1706 ----NPQGPFPTQTL---------SLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP 1752

Query: 847  GTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPV 906
                A+P GPAP  ++  TL P +S+   +  A+        +Q++  +P P      P 
Sbjct: 1753 PLAPASPVGPAPAHTL--TLAPASSSASLLAPAS--------VQTLTLSPAP-----VPT 1797

Query: 907  QAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQL 966
              P    +  L P     P +  S  V       PLP V+    +PV         +   
Sbjct: 1798 LGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLP-VTMVSRLPVSKDEPDTLTLRSG 1856

Query: 967  TPVPVSTPSGL----------VPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALP 1016
             P P ST +             PP SP  L     + ++       RI  +  A G   P
Sbjct: 1857 PPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALAP 1916

Query: 1017 L-GTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAF 1052
            + GT          T   P +S  +G  S GPS P F
Sbjct: 1917 VYGTEVLD----FCTLPQPVAS-PIGPRSPGPSHPTF 1948



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 134/561 (23%), Positives = 181/561 (32%), Gaps = 108/561 (19%)

Query: 832  LPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLP--PGTSTNGKVLAATAPTPGIPIL 889
            LPQ+ +  P    A    +    G     S +   P  PGT  + ++  A A T G    
Sbjct: 2356 LPQEEEEGPG---AGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQG---- 2408

Query: 890  QSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSP-P 948
                  P   A        PP     +  P +  VP  AP        A   +P + P P
Sbjct: 2409 --ANHTPVISAHQTRSTTTPP-----RCSPARERVPRPAPRPRPTPASAPAAIPALVPVP 2461

Query: 949  FSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPL-SPATLPGPTSQPQKVLLPSSTRITYV 1007
             S PV   A  P  I+ +  +P   P   +PP  SPA  P P   P     P   +   V
Sbjct: 2462 VSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLV 2521

Query: 1008 Q--------------SAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFV 1053
                           SA    LPLG  P +       +  P S       S   S  + V
Sbjct: 2522 TPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALA-SPESLELASVASSETSSLSLV 2580

Query: 1054 QPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQ 1113
             P         L P  V + PV    L      P  P +T           S P  Q  +
Sbjct: 2581 PP-------KDLLPVAVEILPVSEKNL---SLTPSAPSLT-------LEAGSIPNGQEQE 2623

Query: 1114 APPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGS-----------MTY 1162
            AP S     A  TT    T+LP+G   P   + +     P + A              + 
Sbjct: 2624 APDS-----AEGTT---LTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSE 2675

Query: 1163 SLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESE 1222
             L   K    SP+ PQ++  A  + P  S  A  S   GP+P +     P R  T+ + E
Sbjct: 2676 ELTEAKTPTSSPEKPQELVTAEVAAPSTSSSA-TSSPEGPSPAR-----PPRRRTSADVE 2729

Query: 1223 LEGQPT-PPAPPPLPETW---------------------TPTARSSPPLPPPAEERTSAK 1260
            + GQ T  P  PP P+                            +S  +P  +E   S  
Sbjct: 2730 IRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPG 2789

Query: 1261 GPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAP-----AVAPGGSSESSSGRAA 1315
             P   +   P SS     P +   +   P  P  P  A       V  GGS E+  G   
Sbjct: 2790 SPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALL 2849

Query: 1316 GDTPERKEAAGTGKKVKVRPP 1336
              TP         K+ + RPP
Sbjct: 2850 AITPP------AVKRRRGRPP 2864



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 105/411 (25%), Positives = 141/411 (34%), Gaps = 74/411 (18%)

Query: 940  QPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLP 999
            QP+P       V V N   P      L PVPV  P G  P LS    PGP  Q    +LP
Sbjct: 999  QPVPKQEGRTVVVVNNPRAP------LGPVPVRPPPG--PELSAQPTPGPVPQ----VLP 1046

Query: 1000 SSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLL-S 1058
            +S  +    SA     PL   PAS                       P GP  + PL  +
Sbjct: 1047 ASLMV----SASPAGPPL--IPASR----------------------PPGPVLLPPLQPN 1078

Query: 1059 AGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSA---PLAQPS--Q 1113
            +G  P + P  +GV    S    P  +    P      S +P P SS+   PL  P    
Sbjct: 1079 SGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYT 1138

Query: 1114 APPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRP- 1172
             PP+   T +T+T     T +P   PAP     +P       +   ++   +A  AQRP 
Sbjct: 1139 FPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPV 1198

Query: 1173 -----SPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLE----PGPVREPTAPESEL 1223
                 S     +++    ++        A G+P P  R  +      G     + P    
Sbjct: 1199 ANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVA 1258

Query: 1224 EGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSA-----KGPETMASK-------FPS 1271
              Q   P P P P +  P   SS P   PA    S      + P TM +           
Sbjct: 1259 LIQAVAPTPGPTPVSVLP---SSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQ 1315

Query: 1272 SSSDWRVPGQGLENRGEPPTPPSPA---PAPAVAPGGSSESSSGRAAGDTP 1319
            +  D   P   L     PP+   PA   P P + PG     + G A    P
Sbjct: 1316 APRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMP 1366



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 188/835 (22%), Positives = 270/835 (32%), Gaps = 124/835 (14%)

Query: 572  RPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLE----PPGPSVIAAPPSGGGNI 627
            RP P  A  PA            P       P ++  +     PP PS I  PP      
Sbjct: 2442 RPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQI--PPCSSPAC 2499

Query: 628  LQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIA 687
                   P               P+  L  G P+ P+S              S T +P+ 
Sbjct: 2500 TPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPIS-------------ASVTNLPLG 2546

Query: 688  SKP-FPTSGRAEASPND---TAGARTEMGTGSRVPGGS--PLGVSLVYSDKKSAAATSPA 741
             +P      +A ASP      + A +E  + S VP     P+ V ++   +K+ + T  A
Sbjct: 2547 LRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSA 2606

Query: 742  PHLV--AGPLL-GTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGA 798
            P L   AG +  G   +AP +     +     G   P  V      +   G      A +
Sbjct: 2607 PSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCV------SESNGLELPPSAAS 2660

Query: 799  GSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKA-AAPSGPA 857
                  P     L+     +     +     P  PQ+L  A   AP+  + A ++P GP+
Sbjct: 2661 DEPLQEP-----LEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPS 2715

Query: 858  PTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQA--PPPGGSA 915
            P    R          G+        PG  +L+ +P       +    V+      G ++
Sbjct: 2716 PARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAAS 2775

Query: 916  QLLPGKVLVPLAAPSMSVRG-GGAGQPLPLVSPPFSVPVQNGAQPPSK-IIQLTPVPVST 973
             L+PG      +  S SVR   G     P+  P  + P  +   PP +  I    + +  
Sbjct: 2776 TLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGV 2835

Query: 974  PSGLVPPLSPATLPG---PTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVT 1030
              G  P      L     P  + ++   P   R       G     +  +P+S+  G   
Sbjct: 2836 TGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRG-----VDEAPSSTLKGKTN 2890

Query: 1031 SYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPV--PSPQLPP------ 1082
               P           GP       P+L     P   P  +G  PV  P+P L P      
Sbjct: 2891 GADPVP---------GPETLIVADPVLEPQLIP--GPQPLGPQPVHRPNPLLSPVEKRRR 2939

Query: 1083 -----ACAAP-GGPVITAFYSGSPAPTSSAPLAQP-SQAPPSLVYTVATSTTPPAATILP 1135
                 A   P  G + +A    S + T   P   P +  PP LV   AT         + 
Sbjct: 2940 GRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTIS 2999

Query: 1136 KGPPAPATATPA--PTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFE 1193
              PP      P   P SP PS            P   R S    +         P G  E
Sbjct: 3000 TSPPKRKRGRPPKNPPSPRPSQL----------PVLDRDSTSVLESCGLGRRRQPQGQGE 3049

Query: 1194 A--GASGRPGPAP-----RQPLEPGPVREPTAPES--------ELEGQPTPPAPPPLPET 1238
            +   +S   G  P     R  LE   +R   +  S        +L+   + P    L   
Sbjct: 3050 SEGSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLEL--- 3106

Query: 1239 WTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQ-GLENRGEPPTPPSPAP 1297
             TP   S  P       R  +  P     K P   +   V G  GL  RG    PPSP  
Sbjct: 3107 -TPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQ-PPSP-- 3162

Query: 1298 APAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPP--LKKTFDSVDNRVL 1350
               + P GS E S   A+G   E +E  GT ++   RP P  L  T +  D R+L
Sbjct: 3163 ---LGPEGSVEESEAEASG---EEEEGDGTPRR---RPGPRRLVGTTNQGDQRIL 3208



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 53/148 (35%), Positives = 63/148 (42%), Gaps = 18/148 (12%)

Query: 1172 PSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTP-P 1230
            P PK P K+K      PV   E G +      PR PL P PVR P  P  EL  QPTP P
Sbjct: 985  PRPK-PVKMKVNRMLQPVPKQE-GRTVVVVNNPRAPLGPVPVRPPPGP--ELSAQPTPGP 1040

Query: 1231 APPPLPETWTPTAR-SSPPLPP----------PAEERTSAKGPETMASKFPSSSSDWRVP 1279
             P  LP +   +A  + PPL P          P  +  S   P+ + S     S   R P
Sbjct: 1041 VPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPP 1100

Query: 1280 GQGLENRGEPPTPPSPAPAPAVAPGGSS 1307
               L  +  PP P   +PAP   PG SS
Sbjct: 1101 TPTLSLKPTPPAPVRLSPAP--PPGSSS 1126



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 168/738 (22%), Positives = 238/738 (32%), Gaps = 117/738 (15%)

Query: 560  QESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPAT-----FRRKRPESVGGLEPPGP 614
            QE  +G  AG       G G      KA    P  P T      R  R E+ G    P  
Sbjct: 2358 QEEEEGPGAGDESSCGTGGGTHRRSKKAKA--PERPGTRVSERLRGARAETQGANHTP-- 2413

Query: 615  SVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAA-------PLSRP 667
             VI+A  +      ++   PP          R    P P+ A  APAA       P+S P
Sbjct: 2414 -VISAHQT------RSTTTPPRCSPARERVPRPAPRPRPTPA-SAPAAIPALVPVPVSAP 2465

Query: 668  AATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSL 727
                  N   P++  PV I   P P S      P  ++ A T     +  P  +P     
Sbjct: 2466 VPISAPN---PITILPVHILPSPPPPS----QIPPCSSPACTPPPACTPPPAHTP----- 2513

Query: 728  VYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQG-AP 786
                       +P+  L+ GP    +    A+VTNL +G         P  +  AQ  A 
Sbjct: 2514 ---PPAQTCLVTPSSPLLLGPPSVPIS---ASVTNLPLGLR-------PEAELCAQALAS 2560

Query: 787  GGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAP 846
                   S A + +     VP   L P A+           ILP   + L + P+     
Sbjct: 2561 PESLELASVASSETSSLSLVPPKDLLPVAVE----------ILPVSEKNLSLTPSAPSLT 2610

Query: 847  GTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAP--PPKAQSVS 904
                + P+G               S  G  L        +P+  S  +    PP A S  
Sbjct: 2611 LEAGSIPNGQEQEAP--------DSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDE 2662

Query: 905  PVQAP--------------PPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFS 950
            P+Q P               P  S +     V   +AAPS S             SP   
Sbjct: 2663 PLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATS--------SPEGP 2714

Query: 951  VPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGP--TSQPQKVLLPSSTRITYVQ 1008
             P +   +  S  +++       P     P     LPG   T   +K L+    R    Q
Sbjct: 2715 SPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELV----RRRRQQ 2770

Query: 1009 SAGGHALPLGTSPASSQAGTVT---SYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLL 1065
                  L  G S  S+  G+ +     GP SS  +G    GP   A    L +  Q P +
Sbjct: 2771 RGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIG----GPCEAAPSSSLPTPPQQPFI 2826

Query: 1066 APGQV--GVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQP---SQAPPSLVY 1120
            A   +  GV+   SP+          P       G P   + +P        +AP S + 
Sbjct: 2827 ARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLK 2886

Query: 1121 --TVATSTTPPAATILPKGPPAPATATPAPT--SPFPSATAGSMTYSLVAPKAQRPSPKA 1176
              T      P   T++   P       P P    P P      +   +   +  RP    
Sbjct: 2887 GKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKAR 2946

Query: 1177 PQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLP 1236
               +   I+S   G+ E+     P P+P  PL P  V  PTA  +      T    PP  
Sbjct: 2947 DLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVC-PTATVANTVTTVTISTSPPKR 3005

Query: 1237 ETWTPTARSSPPLPPPAE 1254
            +   P    +PP P P++
Sbjct: 3006 KRGRPP--KNPPSPRPSQ 3021



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 134/587 (22%), Positives = 193/587 (32%), Gaps = 118/587 (20%)

Query: 1055 PLLSAGQA------PLLAPGQVGVS-PVPSPQLPPACAAPGGPVITAFYSGSPAPTSSA- 1106
            P++SA Q       P  +P +  V  P P P+  PA A    P +      +P P S+  
Sbjct: 2413 PVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPN 2472

Query: 1107 PLA------QPSQAPPSLVYTVATS--TTPPAATILPKGPPAPA-TATPAPTSPF----P 1153
            P+        PS  PPS +   ++   T PPA T  P   P PA T    P+SP     P
Sbjct: 2473 PITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPP 2532

Query: 1154 SATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPV 1213
            S    +   +L  P   RP  +   +  A+  S+ + S  +  +      P  P +  PV
Sbjct: 2533 SVPISASVTNL--PLGLRPEAELCAQALASPESLELASVASSETSSLSLVP--PKDLLPV 2588

Query: 1214 REPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
                 P SE     TP AP    E  +         P  AE  T    PE    + P   
Sbjct: 2589 AVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPE--GEELPLCV 2646

Query: 1274 SDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKV 1333
            S+      GLE       PPS                   AA D P ++           
Sbjct: 2647 SE----SNGLE------LPPS-------------------AASDEPLQE----------- 2666

Query: 1334 RPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKK 1393
               PL+    S                       EE+  + T  S    P+ ++ +    
Sbjct: 2667 ---PLEADRTS-----------------------EELTEAKTPTSSPEKPQELVTAEVAA 2700

Query: 1394 RKNSTDLDSAPEDPTSPKRKMRRRSSCSSE--------PNTPKSAKCEGDIFTFDRTGTE 1445
               S+   S+PE P SP R  RRR+S   E        P  P   K    +     T  E
Sbjct: 2701 PSTSSSATSSPEGP-SPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVE 2759

Query: 1446 AEDVLGELEYDKVPYSSLRRTLDQRRA-----LVMQLFQDHGFFPSAQATAAFQARYADI 1500
             ++++      +   S+L   + +  A      V  +       P      A  +     
Sbjct: 2760 EKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPT 2819

Query: 1501 FPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPT-----GTAAAPAPTPSPAG 1555
             P +  +    R +   +    +P     G  A L + PP      G       +P+ AG
Sbjct: 2820 PPQQPFIAR--RHIELGVTGGGSPEN---GDGALLAITPPAVKRRRGRPPKKNRSPADAG 2874

Query: 1556 -GPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGP 1601
             G D    S+  G    A P+P P       P  E    P P P GP
Sbjct: 2875 RGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGP 2921



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 37/127 (29%), Positives = 48/127 (37%), Gaps = 12/127 (9%)

Query: 41   VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGA 100
            VP   P  P+ S QP+    P   P +   S  PA    +   RPPG      P +P   
Sbjct: 1022 VPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPV-LLPPLQPNSG 1080

Query: 101  TCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEI 160
            + P+      P PLGV+     PP  T      PP   RL             S++ P  
Sbjct: 1081 SLPQV----LPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSS----SLLKP-- 1130

Query: 161  QLPLPPG 167
             L +PPG
Sbjct: 1131 -LTVPPG 1136



 Score = 40.4 bits (93), Expect = 0.014
 Identities = 119/536 (22%), Positives = 175/536 (32%), Gaps = 98/536 (18%)

Query: 1133 ILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSP-KAPQKVKAA--IASIPV 1189
            ++   P AP    P    P P  +A             +P+P   PQ + A+  +++ P 
Sbjct: 1010 VVVNNPRAPLGPVPVRPPPGPELSA-------------QPTPGPVPQVLPASLMVSASPA 1056

Query: 1190 GSFEAGASGRPGPAPRQPLEPGPVREPTA--------------PESELEGQPTPPAPPPL 1235
            G     AS  PGP    PL+P     P                P   L  +PTPPAP  L
Sbjct: 1057 GPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRL 1116

Query: 1236 PETWTPTARS--SPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPP 1293
                 P + S   P   PP      A    T  +   ++++    P    +     P   
Sbjct: 1117 SPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQ 1176

Query: 1294 SPAPAPAVAPGGSSESSSGR----AAGDTPERKEAAG-----TGKKVKV----RPPPLKK 1340
            +  P+  V   G   S + R    A G  P   +  G     TG +V+     +P PL++
Sbjct: 1177 ARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQR 1236

Query: 1341 TFDSV-----DNRVLSE---VDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRK 1392
                +      + ++S+   V   +  A  P   P  VLPS T  S   +P  +      
Sbjct: 1237 NVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSST-PSTTPAPTGLSLPLAA 1295

Query: 1393 KRKNSTDLDS----------APEDPTSPKRKM----RRRSSCSSEPNTPKSAKCEGDIFT 1438
             +   T +++          AP D  +P   +    R  SS       P+     G + T
Sbjct: 1296 NQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPT 1355

Query: 1439 FDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYA 1498
                       LG      +P  +L R L         L   H   P   A+A   A   
Sbjct: 1356 ---------PTLGTARAP-MPTPTLVRPL---------LKLVHSPSPEVSASAPGAAPLT 1396

Query: 1499 DIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVP-------PPTGTAAAPAPTP 1551
               P  V   L         +  ++P   P  +   +P+        P T  A A AP  
Sbjct: 1397 ISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLT 1456

Query: 1552 SPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATG 1607
             P   P   S S  +      PPL P   + PG P    +  PS   P  S    G
Sbjct: 1457 IPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP----SLAPSGASPSASALTLG 1508



 Score = 39.7 bits (91), Expect = 0.024
 Identities = 30/105 (28%), Positives = 40/105 (38%), Gaps = 8/105 (7%)

Query: 1502 PSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTS 1561
            P K+ +   ++ V ++  +       P     P+PV PP G   +  PTP P   P    
Sbjct: 989  PVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPV--PQVLP 1046

Query: 1562 PSSDSGTAQAAPPL------PPPPESGPGQPGWEGAPQPSPPPPG 1600
             S     + A PPL      P P    P QP     PQ  P P G
Sbjct: 1047 ASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLG 1091



 Score = 37.7 bits (86), Expect = 0.090
 Identities = 43/173 (24%), Positives = 61/173 (35%), Gaps = 25/173 (14%)

Query: 1108 LAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSL--- 1164
            + QP          V  +   P   +  + PP P  +      P P     S+  S    
Sbjct: 997  MLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPA 1056

Query: 1165 ---VAPKAQRPSPKAPQKVKAAIASI------PVGSFEAGASGRPGPA-PRQPLEPGPVR 1214
               + P ++ P P     ++    S+      P+G   +G S  P P    +P  P PVR
Sbjct: 1057 GPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVL-SGTSRPPTPTLSLKPTPPAPVR 1115

Query: 1215 EPTAP---ESEL-------EGQPTPPAPPPLPETWTPTARSSP-PLPPPAEER 1256
               AP    S L        G   PPA      T T TA ++  P P PA +R
Sbjct: 1116 LSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQR 1168



 Score = 35.4 bits (80), Expect = 0.45
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 10/88 (11%)

Query: 1529 PGAEAPLPVPPPTGTAAAP-----APTPSPAGGPDPT-SPSSDSGTAQAAPPLPPP---P 1579
            P + A   +  P    AAP     AP+P+P   P P  +PS  +    A+   P P   P
Sbjct: 1575 PASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAP 1634

Query: 1580 ESGPGQPGWEGAPQPSPPPP-GPSTAAT 1606
             S PG      +P P+P P   PS+  T
Sbjct: 1635 SSTPGTSLASASPVPAPTPVLAPSSTQT 1662



 Score = 34.7 bits (78), Expect = 0.76
 Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 10/93 (10%)

Query: 49   PDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGP 108
            PDP  +P   +   +  +     +E      V + R P G     P  PPG      P P
Sbjct: 981  PDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRP--PPGPELSAQPTP 1038

Query: 109  GP-----PHPLGVVESGKGPPPTTEEEASGPPG 136
            GP     P  L V  S  GPP      AS PPG
Sbjct: 1039 GPVPQVLPASLMVSASPAGPPLI---PASRPPG 1068



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 35/110 (31%), Positives = 43/110 (39%), Gaps = 24/110 (21%)

Query: 1521 AATPTEQPPGAEAPLPVPPPTGT-AAAPAPTPSPAG---------------GPDPTSPSS 1564
            ++T T  P    +PLP P  T T A APA  P+  G               GP PT   S
Sbjct: 1658 SSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLS 1717

Query: 1565 DSGTAQAAP------PLPPPPESGPGQP-GWEGAPQPSPPPP-GPSTAAT 1606
             +  +   P       L P P  GP Q      AP  +P  P GP+ A T
Sbjct: 1718 LTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHT 1767



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 9/82 (10%)

Query: 1522 ATPTEQPPGAEAPLPVPPPTGTAAAPAPTPS--PAGGPDPTSPSSDSGTAQAAPPLPPPP 1579
            A  + Q P ++A   V   +G A  P    S  P    +P     D+ T ++ PP PP  
Sbjct: 1809 APASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEP-----DTLTLRSGPPSPPST 1863

Query: 1580 ESGPGQPGWEGAPQPSPPPPGP 1601
             +  G P      QP PPP  P
Sbjct: 1864 ATSFGGP--RPRRQPPPPPRSP 1883



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 17/51 (33%), Positives = 23/51 (45%), Gaps = 3/51 (5%)

Query: 1531 AEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAP---PLPPP 1578
            ++ P+PV  P+ T      + SP   P P    S + T   AP   PLP P
Sbjct: 1625 SQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSP 1675



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 27/91 (29%), Positives = 33/91 (36%), Gaps = 8/91 (8%)

Query: 1521 AATPTEQPPGAEAPLPVPPPTGTAAAPAP-TPSPAGGPDPTSPSSDSGTAQAAPPLPPPP 1579
            AA P   P    AP+P+  P      P    PSP   P P+     S  A   PP   PP
Sbjct: 2452 AAIPALVPVPVSAPVPISAPNPITILPVHILPSP---PPPSQIPPCSSPACTPPPACTPP 2508

Query: 1580 ESGPGQPGWEGAPQPSPP----PPGPSTAAT 1606
             +    P       PS P    PP    +A+
Sbjct: 2509 PAHTPPPAQTCLVTPSSPLLLGPPSVPISAS 2539



 Score = 31.6 bits (70), Expect = 6.5
 Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 10/112 (8%)

Query: 1502 PSKVCLQLKIREVRQKIMQAATPTEQP------PGAEAPLPVPPPTGTAAAPAPTPSPAG 1555
            P++  L        Q +     P   P      P    PL   P    +   AP  + + 
Sbjct: 1567 PAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQ 1626

Query: 1556 GPDPT-SPSSDSGT--AQAAP-PLPPPPESGPGQPGWEGAPQPSPPPPGPST 1603
             P P  +PSS  GT  A A+P P P P  +         AP PSP P   ST
Sbjct: 1627 TPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPAST 1678



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 36/150 (24%), Positives = 55/150 (36%), Gaps = 13/150 (8%)

Query: 20   GMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAA 79
            G  + T+V P    V P     P LAPS   PS          +  ++S+Q+       A
Sbjct: 1469 GPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLA 1528

Query: 80   VAHERPPGGTGSADPERPP---GATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPG 136
                  PG   +  P   P    A+   SP P  P+P    ++    P ++  +A   P 
Sbjct: 1529 PTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNP-APAQASLLAPASSASQALATPL 1587

Query: 137  EPRLDSETESDHDDAFLSIMSPEIQLPLPP 166
             P    +T         +I++P    PL P
Sbjct: 1588 APMAAPQT---------AILAPSPAPPLAP 1608



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 33/107 (30%), Positives = 40/107 (37%), Gaps = 21/107 (19%)

Query: 1521 AATPTEQPPGAEAPLPVP-------PPTGTAAA---PAPTP----------SPAGGPDPT 1560
            A +P   P  A +  PVP       P T  A+A   PAPTP           PA  P P 
Sbjct: 1613 APSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPL 1672

Query: 1561 SPSSDSGTAQAAPPLPPP-PESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
               + + T   AP L P    S P Q    G   P  P P  + + T
Sbjct: 1673 PSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLT 1719


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score =  126 bits (316), Expect = 2e-28
 Identities = 257/992 (25%), Positives = 338/992 (34%), Gaps = 233/992 (23%)

Query: 510  LDPEPPGP-PDPPVAF---------GKGYGSAPSSSASSPASSSASAATSFSLGSGTFKA 559
            L+PEP  P P   + F           G G   S  A  P      +    ++   T +A
Sbjct: 61   LNPEPNQPAPSVDLDFLEDDILGSPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEA 120

Query: 560  Q-ESGQGSTAGPLRPP------PPGAGGPATPSKATRFL-PMDPATFRRKRPESV---GG 608
            + E   G    P   P      P GAGG A  +   + L P        + P +V     
Sbjct: 121  EAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQA 180

Query: 609  LEPPGPSVIAA-------PPSGGGNI-LQTLV-LPPNKEEQEGGGARVPSAPAPSLAYGA 659
            L PP   V  A        P G GN+ LQ +  L        GG        AP    G 
Sbjct: 181  LVPPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQ 240

Query: 660  PAAPLSRPAATMVTNVVRPVS---------STPVPIASKPFPTSGRAEASPNDTAGARTE 710
            P   L+ P + ++   V PVS         S PV +AS      G       + + A   
Sbjct: 241  PVMALNTPTSQLLAKQV-PVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVAT 299

Query: 711  MGTGSRV---------PGGSPLGVSLVYSDKKSAAATSPAPHLV------------AGPL 749
               G+ V         P G+P G  L  +    ++   PAP+++            AG L
Sbjct: 300  TLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVL 359

Query: 750  ------LGTVGKAPATVTNLLVGTPGYGAPAPPAVQ---FIAQGAPGGGTT-AGSGAGA- 798
                  L     APA  T  + G PG     P A Q   F+A G  G     +G  A A 
Sbjct: 360  PPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPAL 419

Query: 799  -------------GSGPNGPVPLGILQPGALGKAGGIT------------------QVQY 827
                         G+ P  P       PGAL K   +                   Q Q+
Sbjct: 420  QANVFKQPPATTTGAAPPQP-------PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF 472

Query: 828  ILP-----TLPQQLQVAPA-------PAPAPGTKAAAPSGPAPTT-------SIRFTLPP 868
            +LP      LPQQL   PA        A AP T     + P  T        S+   L P
Sbjct: 473  LLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAP 532

Query: 869  GTSTNGKVLAATAPTP-GIPIL--------------QSVPSAPPPKAQSVSPVQAPPPGG 913
             +  +   + + AP   G P L              QS P+   P A +V      PP  
Sbjct: 533  HSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSA 592

Query: 914  SAQLLPGKVLVPLAAPSMSVRGGG---AGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVP 970
             A L     LV  A P+ +          QP P   P  S P+  G Q P       P  
Sbjct: 593  VAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQA---QQPPQ 649

Query: 971  VSTPSGLVPP--LSPATLPGPTSQPQKVLL--PSSTRITYVQSAGGHALPLGTSPASSQA 1026
              TP    PP   +P   PG  S P+K++L  P S   T + +     + L   P     
Sbjct: 650  APTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFL---PQERSQ 706

Query: 1027 GTVTSYGPTSSVALGFTSLGP---SGPAFVQPLLS-AGQAPLLAPGQVGVSPVPSPQLPP 1082
              +++ GP  SV        P     PA   P+   AG  P     Q   SP P+PQ+P 
Sbjct: 707  QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQA--SPAPAPQIPA 764

Query: 1083 ACAAPG-GPVITAFYSGSPAPTSSAPLA-----------QPSQAPPSLVYTVATSTTPPA 1130
            A    G GP      S SP+    APL            +P   PPS   +V+   + P 
Sbjct: 765  AAPLKGPGP------SSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPP 818

Query: 1131 ATILP--KGPPA--------------PATATPAPTSPFPSATAGSMTYSLVAPKAQRPS- 1173
                P  + PP               P  + PAPT+P P           + P++Q P  
Sbjct: 819  LHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP-------LRPQSQPPEG 871

Query: 1174 --PKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQ-----PLEPGPVREPTAPES-ELEG 1225
              P AP    ++ +S    S E  +S  P P P       P   GP + PT P +  L  
Sbjct: 872  PLPPAPHLPPSSTSSAVASSSET-SSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVP 930

Query: 1226 QPTPPAPPPLPETWTPTARSSPPLPPPAE--ERT---------------SAKGPETMASK 1268
            +P  P PPP P T+       P LP P    ER                +   P+T  S 
Sbjct: 931  EPAAPPPPP-PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989

Query: 1269 FPSSSSDWRVPGQGLENRGEPPTPPSPAPAPA 1300
             P +S    V   G    G P T PS APAPA
Sbjct: 990  GPLTSPAASVLVSGQAPSGTP-TAPSHAPAPA 1020



 Score =  100 bits (248), Expect = 1e-20
 Identities = 224/867 (25%), Positives = 309/867 (35%), Gaps = 153/867 (17%)

Query: 518  PDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPG 577
            P  PV       S   +      + SA+ AT+ + G+  F     G G+ + P   P   
Sbjct: 269  PSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLN-GNSVF----GGAGAASAPTGTP--- 320

Query: 578  AGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNK 637
            +G P   +      P+ PA            +    P+ I   P+G        VLPP  
Sbjct: 321  SGQPLAVAPGLGSSPLVPAP---------NVILHRTPTPIQPKPAG--------VLPPKL 363

Query: 638  EEQEGGGARVPSAPAPSLA--YGAPAAPLSRPAATM-VTNVVRPVSSTPVPIASKPFPT- 693
             +        P APA +     G P A   +P A   +T +    +   V ++  P P  
Sbjct: 364  YQL----TPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPAL 419

Query: 694  -SGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGT 752
             +   +  P  T GA      G+      P+ V L+    + ++   PA H++ G     
Sbjct: 420  QANVFKQPPATTTGAAPPQPPGAL---SKPMSVHLL---NQGSSIVIPAQHMLPGQNQFL 473

Query: 753  VGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPG-GGTTAGSGAGAGSGPNGPVPLG-I 810
            +  APA      +       PA    Q +A  AP  GG    +         GP+ LG +
Sbjct: 474  LPGAPAVQLPQQLSA----LPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPV 529

Query: 811  LQPGALGKAGGITQVQYILPTLPQ--QLQVAPAPAPAPGTKAAAPSGPAPTTSIR-FTLP 867
            L P +   +  I     I    P   Q+ V+ A    P     AP+GPA TT ++  TLP
Sbjct: 530  LAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLP 589

Query: 868  PGT-----STNGKVLAAT---APTPGIPIL--QSVPSAPP-------------------- 897
            P       + +G V  AT   A     P+L  Q  P APP                    
Sbjct: 590  PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649

Query: 898  -PKAQSVSPVQAPPPGGSAQLL--PGKVLV---PLAAPS---------MSVRGGGAGQPL 942
             P  Q+ +P QA  P  S  L   P K+++   P A P+         M +    + QPL
Sbjct: 650  APTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPL 709

Query: 943  PLVSPPFSVPVQNGAQPPSKIIQLTPV-PVSTPSGLVPPL-----SPATLPG-PTSQPQK 995
                P  SVP       P       P  PV+  +GL P       SPA  P  P + P K
Sbjct: 710  SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769

Query: 996  VLLPSSTRITYVQSAGGHALPLGTSP--ASSQAGTVTSYGPTSSVALGFTSLGPSGPAFV 1053
               PSS+       +  H  PLG SP   S       S  P+   ++   S  PS P  +
Sbjct: 770  GPGPSSS------PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSV---SRPPSEPP-L 819

Query: 1054 QPLLSAGQAPLLAPG------QVGVSPVPSPQLPPACAAPGGPVITAFYSGSP--APTSS 1105
             P     QAP   PG      Q+GV P   P   PA  APG P         P   P   
Sbjct: 820  HPC-PPPQAPPTLPGIFVIQNQLGVPP---PASNPAPTAPGPPQPPLRPQSQPPEGPLPP 875

Query: 1106 APLAQPSQAPPSLVYTVATSTTPPAATILP------------KGPPAPATA--TPAPTSP 1151
            AP   PS    ++  +  TS+  PA T               K P  P T    P P +P
Sbjct: 876  APHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAP 935

Query: 1152 FPSATAGSMTYSLVA-PKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEP 1210
             P       T+ +V  P    P PKA   +      +P G      +G    AP+     
Sbjct: 936  PPPPPR---TFQMVTTPFPALPQPKA---LLERFHQVPSGIILQNKAGGAPAAPQTSTSL 989

Query: 1211 GPVREPTAPESELEGQP--TPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASK 1268
            GP+  P A        P  TP AP   P      A   PPL  PAE +  A    T+   
Sbjct: 990  GPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPL-LPAENKAFASNLPTLNVA 1048

Query: 1269 FPSSSSDWRVPGQGLENR----GEPPT 1291
              +SS   +  G   E++     +PPT
Sbjct: 1049 KAASSGPGKPSGLQYESKLSGLKKPPT 1075



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 185/762 (24%), Positives = 255/762 (33%), Gaps = 137/762 (17%)

Query: 507  RPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGS 566
            +PP       PP PP A  K      S    +  SS    A     G   F    +    
Sbjct: 426  QPPATTTGAAPPQPPGALSKPM----SVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQ 481

Query: 567  TAGPLRPPPPGAGGP----ATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPS 622
                L   P   GG     A P    + +     T      +++ G    GP V+A  P 
Sbjct: 482  LPQQLSALPANVGGQILAAAAPHTGGQLIANPILT-----NQNLAGPLSLGP-VLA--PH 533

Query: 623  GGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSS- 681
             G +    L   P +  Q        S  A SL   +  AP    A T++  V  P S+ 
Sbjct: 534  SGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAV 593

Query: 682  ----TPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAA 737
                TP  +     P +   EA+P  T     +       P   PLG+    + +   A 
Sbjct: 594  AMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTP--LPLGLQQPQAQQPPQA- 650

Query: 738  TSPAPHLVAGPLLGTVGKAPATVTN---LLVGTPGYGAPAPPAVQ-----FIAQGAPGGG 789
              P P   A P   T   +P   ++   +++G P    P     Q     F+ Q      
Sbjct: 651  --PTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQP 708

Query: 790  TTAGSGAGAGSGPNGPVPLGIL--QPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPG 847
             +A        GP+  VP  ++   P         T V       PQ      +PAPAP 
Sbjct: 709  LSA-------EGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ 761

Query: 848  TKAAAP---SGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVS 904
              AAAP    GP+ + S+    P G S +       +P P  P     PS PP + QSVS
Sbjct: 762  IPAAAPLKGPGPSSSPSLPHQAPLGDSPH-----LPSPHPTRP-----PSRPPSRPQSVS 811

Query: 905  PVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKII 964
               + PP           L P   P          Q  P +   F +  Q G  PP+   
Sbjct: 812  RPPSEPP-----------LHPCPPP----------QAPPTLPGIFVIQNQLGVPPPAS-- 848

Query: 965  QLTPVPVSTPSGLVPPLSPATLP--GPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPA 1022
               P P + P    PPL P + P  GP   P   L PSST      S+   +     +P+
Sbjct: 849  --NPAPTA-PGPPQPPLRPQSQPPEGPLP-PAPHLPPSSTSSAVASSSETSSRLPAPTPS 904

Query: 1023 SSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPP 1082
              Q     S GP  S         P+ P  +  +      P   P    +   P P LP 
Sbjct: 905  DFQLQFPPSQGPHKS---------PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQ 955

Query: 1083 ACA-------APGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILP 1135
              A        P G ++     G+PA    AP    S  P           T PAA++L 
Sbjct: 956  PKALLERFHQVPSGIILQNKAGGAPA----APQTSTSLGP----------LTSPAASVLV 1001

Query: 1136 KGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAG 1195
             G     T T    +P P+  A           A    P  P + KA  +++P  +    
Sbjct: 1002 SGQAPSGTPTAPSHAPAPAPMA-----------ATGLPPLLPAENKAFASNLPTLNVAKA 1050

Query: 1196 ASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPE 1237
            AS  PG       +P  ++     ES+L G   PP   P  E
Sbjct: 1051 ASSGPG-------KPSGLQY----ESKLSGLKKPPTLQPSKE 1081



 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 213/919 (23%), Positives = 313/919 (34%), Gaps = 180/919 (19%)

Query: 776  PAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQ 835
            P +Q +  G+PGG T A  G         PV + +  P +          Q +   +P  
Sbjct: 212  PGLQGLPNGSPGGATAATLGLAPIQVVGQPV-MALNTPTS----------QLLAKQVPVS 260

Query: 836  LQVAPAPAPA-PGTKAAA---PSGPAPTTSIRFTLPPGTSTNGKVL-----AATAPT--- 883
              +A A  P+ P T A+A   P G         +    T+ NG  +     AA+APT   
Sbjct: 261  GYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTP 320

Query: 884  PGIPI-----LQSVPSAPPPKA---QSVSPVQAPPPGGSAQLLPGKV--LVPL----AAP 929
             G P+     L S P  P P     ++ +P+Q  P G    +LP K+  L P     A  
Sbjct: 321  SGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAG----VLPPKLYQLTPKPFAPAGA 376

Query: 930  SMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPV----------STPSGLVP 979
            +++++G     P    +P     +  G    + ++   P P           +T +G  P
Sbjct: 377  TLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAP 436

Query: 980  PLSPATLPGPTS-----QPQKVLLPSSTRIT-----YVQSAGGHALP--LGTSPASSQAG 1027
            P  P  L  P S     Q   +++P+   +       +  A    LP  L   PA+    
Sbjct: 437  PQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQ 496

Query: 1028 TVTSYGPTSSVALG----FTSLGPSGPAFVQPLLS----AGQAPLLAPGQVGVSPVPSPQ 1079
             + +  P +   L      T+   +GP  + P+L+    A  A +L+   + V      Q
Sbjct: 497  ILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQ 556

Query: 1080 LPPACAA----------PGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPP 1129
            +P + AA          P GP  T    G   P S+  +      P  LV       TP 
Sbjct: 557  MPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLN---TPDGLVQPA----TPA 609

Query: 1130 AATILPKGPPAPA-TATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIP 1188
            AAT    G  AP  T  PAP +P   A +  +   L  P+AQ+P P+AP    AA     
Sbjct: 610  AAT----GEAAPVLTVQPAPQAP--PAVSTPLPLGLQQPQAQQP-PQAPTPQAAA----- 657

Query: 1189 VGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLP-----ETWTPTA 1243
                       P  A      PG     ++PE  + GQP    P  +      + + P  
Sbjct: 658  -----------PPQATTPQPSPGLA---SSPEKIVLGQPPSATPTAILTQDSLQMFLPQE 703

Query: 1244 RSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAP 1303
            RS  PL        SA+GP               VP   + +   PP    PAPA  VA 
Sbjct: 704  RSQQPL--------SAEGPHLS------------VPASVIVSA--PPPAQDPAPATPVAK 741

Query: 1304 G---GSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFA 1360
            G   G     S  +    P+   AA          P L       D+  L       R  
Sbjct: 742  GAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS-PHPTRPP 800

Query: 1361 ELPEFRPEEVL---------PSPTLQSLATSPR--AILGSYRKKRKNSTDLDSAPEDPTS 1409
              P  RP+ V          P P  Q+  T P    I          S    +AP  P  
Sbjct: 801  SRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP 860

Query: 1410 PKRKMRR--RSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTL 1467
            P R   +         P+ P S+       + + +         + +    P     ++ 
Sbjct: 861  PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSP 920

Query: 1468 DQRRALVM------------QLFQDHGF-FPSAQATAAFQARYADIFPSKVCLQLKI--R 1512
                 L +            + FQ     FP+     A   R+  + PS + LQ K    
Sbjct: 921  TPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQV-PSGIILQNKAGGA 979

Query: 1513 EVRQKIMQAATPTEQPPGA---EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTA 1569
                +   +  P   P  +       P   PT  + APAP P  A G  P  P+ +   A
Sbjct: 980  PAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFA 1039

Query: 1570 QAAPPL--PPPPESGPGQP 1586
               P L       SGPG+P
Sbjct: 1040 SNLPTLNVAKAASSGPGKP 1058



 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 202/901 (22%), Positives = 285/901 (31%), Gaps = 178/901 (19%)

Query: 783  QGAPGGG--TTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILP--TLPQQLQV 838
            Q A GG   T AG  A   +GP    P      G  G    +T    + P   + + L V
Sbjct: 135  QPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSV 194

Query: 839  AP----------APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPG--- 885
             P             P PG +      P   T+    L P       V+A   PT     
Sbjct: 195  QPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLA 254

Query: 886  --IPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAP--SMSVRGGGAGQP 941
              +P+   + SA  P            P G+  ++   +   +A      SV GG     
Sbjct: 255  KQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAAS 314

Query: 942  LPLVSP---PFSVPVQNGAQP----PSKIIQLTPVPVST-PSGLVPPLSPATLPGPTSQP 993
             P  +P   P +V    G+ P    P+ I+  TP P+   P+G++PP      P P +  
Sbjct: 315  APTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFA-- 372

Query: 994  QKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSS--VALGFTSLGPSGPA 1051
                 P+   +T     G  ALP    P + Q  T  + G      V  GF +       
Sbjct: 373  -----PAGATLTIQGEPG--ALP--QQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANV 423

Query: 1052 FVQP-LLSAGQAPLLAPGQVG-------VSPVPSPQLPPACAAPGGPVITAFYSGSPAPT 1103
            F QP   + G AP   PG +        ++   S  +P     PG         G+PA  
Sbjct: 424  FKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF--LLPGAPAVQ 481

Query: 1104 SSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYS 1163
                L   S  P ++   +  +  P     L   P         P S  P     S  +S
Sbjct: 482  LPQQL---SALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHS 538

Query: 1164 LVAPKAQRPSPKAPQKV-KAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESE 1222
                 A      AP +V + A+  +PV S  AG+     P   QP   GP     A  + 
Sbjct: 539  AHILSA------APIQVGQPALFQMPV-SLAAGSL----PTQSQPAPAGP-----AATTV 582

Query: 1223 LEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQG 1282
            L+G   PP+   +  T  P     P  P  A   T    P       P +      P   
Sbjct: 583  LQGVTLPPSAVAMLNT--PDGLVQPATPAAA---TGEAAPVLTVQPAPQAPPAVSTP--- 634

Query: 1283 LENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTF 1342
            L    + P    P  AP        ++++ + +       E    G+     P  +  T 
Sbjct: 635  LPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAIL-TQ 693

Query: 1343 DSVDNRVLSEVDFEERFAELPEFR-PEEVL---PSPTLQSLATSPRAILGSYRKKRKNST 1398
            DS+   +  E   +   AE P    P  V+   P P       +P A         K + 
Sbjct: 694  DSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVA---------KGAG 744

Query: 1399 DLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKV 1458
                AP+   SP          +  P  P +A  +G                        
Sbjct: 745  LGPQAPDSQASP----------APAPQIPAAAPLKG------------------------ 770

Query: 1459 PYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKI 1518
            P  S   +L  +  L      D    PS   T     R     PS+   Q   R   +  
Sbjct: 771  PGPSSSPSLPHQAPL-----GDSPHLPSPHPT-----RPPSRPPSRP--QSVSRPPSEPP 818

Query: 1519 MQAATPTEQPPGA------EAPLPVPPPTGTAAAPAPTP---------SPAGGP------ 1557
            +    P + PP        +  L VPPP    A  AP P          P  GP      
Sbjct: 819  LHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPH 878

Query: 1558 -DPTSPS----SDSGTAQAAPPLPP-------PPESGPGQ-----PGWEGAPQPSPPPPG 1600
              P+S S    S S T+   P   P       PP  GP +     P     P+P+ PPP 
Sbjct: 879  LPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938

Query: 1601 P 1601
            P
Sbjct: 939  P 939



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 41/172 (23%), Positives = 63/172 (36%), Gaps = 34/172 (19%)

Query: 44  LAPSQPDPSVQPSEAQQ-PASHPVASNQSKEPAESAAVAHERPPGGTG------------ 90
           L P  PD    P+ A Q PA+ P+   +   P+ S ++ H+ P G +             
Sbjct: 745 LGPQAPDSQASPAPAPQIPAAAPL---KGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS 801

Query: 91  ---------SADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLD 141
                    S  P  PP   CP    P     + V+++  G PP     A   PG P+  
Sbjct: 802 RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP 861

Query: 142 SETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPN 193
              +S           PE  LP  P    + + SA+    ++SS     +P+
Sbjct: 862 LRPQS---------QPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 185/852 (21%), Positives = 267/852 (31%), Gaps = 128/852 (15%)

Query: 509  PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTA 568
            PL  + P    PP A      + P ++   P+   AS+     LG               
Sbjct: 636  PLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG--------------- 680

Query: 569  GPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGG--LEPPGPSVIAAPPSGGGN 626
               +PP        T      FLP +    R ++P S  G  L  P   +++APP     
Sbjct: 681  ---QPPSATPTAILTQDSLQMFLPQE----RSQQPLSAEGPHLSVPASVIVSAPPPAQDP 733

Query: 627  ILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPI 686
               T V        +   ++   APAP +     AAPL  P  +   ++         P 
Sbjct: 734  APATPVAKGAGLGPQAPDSQASPAPAPQIP---AAAPLKGPGPSSSPSLPHQAPLGDSPH 790

Query: 687  ASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVA 746
               P PT       P     +R +  + SR P   PL           A  T P   ++ 
Sbjct: 791  LPSPHPTR------PPSRPPSRPQ--SVSRPPSEPPLHPC----PPPQAPPTLPGIFVIQ 838

Query: 747  GPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGG----------TTAGSGA 796
              L       P   +N     P   AP PP      Q  P  G          ++  S  
Sbjct: 839  NQL-----GVPPPASN-----PAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAV 888

Query: 797  GAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPA----PAPGT---- 848
             + S  +  +P     P         +Q  +  PT P  L + P PA    P P T    
Sbjct: 889  ASSSETSSRLPAPT--PSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMV 946

Query: 849  KAAAPSGPAPTTSI-RF-TLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPV 906
                P+ P P   + RF  +P G     K   A A       L  + S   P A  +   
Sbjct: 947  TTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS---PAASVLVSG 1003

Query: 907  QAP---PPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKI 963
            QAP   P   S    P  +      P +          LP ++   +    +G   PS +
Sbjct: 1004 QAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLN--VAKAASSGPGKPSGL 1061

Query: 964  IQLTPVP-VSTPSGLVPPLSPATLPGPTSQPQKVLLPS-STRITYVQSAGGHALPL---- 1017
               + +  +  P  L P      L         VL P   T     + A    LP     
Sbjct: 1062 QYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQ 1121

Query: 1018 GTSPASSQAGTVTSYGPTSSVAL---------GFTSLGPSGPAFVQPLLSAGQAPLLAPG 1068
            G  P+ S    V     T S  L          +  L       V P         +   
Sbjct: 1122 GALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQ 1181

Query: 1069 QVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTP 1128
            +   +     QL  A   P   V ++   G P   SS     P   P S     A++  P
Sbjct: 1182 EEKTTLALDKQL--AKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPP 1239

Query: 1129 P---AATILPKGPP--APATATPAPTSPFPSATAGSMTYSLVAPKAQRPSP---KAPQKV 1180
            P      ++  G    +P+      +S   S+++ S   S +      P P   + P K 
Sbjct: 1240 PHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKT 1299

Query: 1181 KAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWT 1240
              A + I +       +G         L+P  V +P  P + L+    PP PPP P    
Sbjct: 1300 YEARSRIGLKLKIKQEAGLSKVVHNTALDP--VHQPPPPPATLKVAEPPPRPPPPP---P 1354

Query: 1241 PTARSSPPL--PPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPP----- 1293
            PT + +  +  PPPA       G      + P   + +R      EN G P  P      
Sbjct: 1355 PTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKT-YR------ENVGGPGAPEGTPAG 1407

Query: 1294 -----SPAPAPA 1300
                 SPAP PA
Sbjct: 1408 RARGGSPAPLPA 1419



 Score = 40.4 bits (93), Expect = 0.014
 Identities = 44/148 (29%), Positives = 54/148 (36%), Gaps = 29/148 (19%)

Query: 1485 PSAQATAAFQARYADIF-PSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGT 1543
            PSA  TA        +F P +   Q    E     + A+     PP A+ P P  P    
Sbjct: 683  PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742

Query: 1544 A----------AAPAPTP-----SPAGGPDPTS--------PSSDSGTAQAAPPLPPP-- 1578
            A          A+PAP P     +P  GP P+S        P  DS    +  P  PP  
Sbjct: 743  AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802

Query: 1579 PESGP---GQPGWEGAPQPSPPPPGPST 1603
            P S P    +P  E    P PPP  P T
Sbjct: 803  PPSRPQSVSRPPSEPPLHPCPPPQAPPT 830



 Score = 40.4 bits (93), Expect = 0.014
 Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 27/99 (27%)

Query: 1524 PTEQPP-GAEAPLPVPPPTGTAAA-----------PAPTPS-------PAGGP--DPTSP 1562
            P  QPP G   P P  PP+ T++A           PAPTPS       P+ GP   PT P
Sbjct: 864  PQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPP 923

Query: 1563 SSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGP 1601
             +     + A P PPPP +      ++    P P  P P
Sbjct: 924  PTLHLVPEPAAPPPPPPRT------FQMVTTPFPALPQP 956



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 63/250 (25%), Positives = 87/250 (34%), Gaps = 39/250 (15%)

Query: 468  KERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRP---PLDPEPPG-----PPD 519
            +E+ T +     + E P+      R +  P+  SS  H  P   PL    PG     PP 
Sbjct: 1182 EEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPH 1241

Query: 520  PPVAFGKGYGSAPSSSASS--PASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPP- 576
             P      +G A  S + +   ASSS S+++S S  + +  A E G      P R  PP 
Sbjct: 1242 LPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDG----PMPSRNRPPI 1297

Query: 577  -------------GAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSG 623
                              A  SK      +DP       P ++   EPP       PP+G
Sbjct: 1298 KTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTG 1357

Query: 624  GGNILQTLVLPPNKEEQEGGGA----RVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPV 679
              N       P   E +  G A    R+P         G P AP   PA        R  
Sbjct: 1358 QMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAG-------RAR 1410

Query: 680  SSTPVPIASK 689
              +P P+ +K
Sbjct: 1411 GGSPAPLPAK 1420



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 92/410 (22%), Positives = 135/410 (32%), Gaps = 86/410 (20%)

Query: 714  GSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAP 773
            G R+PG  PL      S     A+T P PHL                T L++   G G  
Sbjct: 1218 GHRLPGHGPL------SSSAPGASTQPPPHLP---------------TKLVIRHGGAGGS 1256

Query: 774  APPAVQFIAQGAPGGGTTAGSGAGAG--SGPNGPVPLGILQPGALGKAGGITQVQYILPT 831
              P+V +    +    +++ S A +   +  +GP+P     P    +A     ++  +  
Sbjct: 1257 --PSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQ 1314

Query: 832  LPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQS 891
                 +V    A  P         P P  +++   PP             P P       
Sbjct: 1315 EAGLSKVVHNTALDP-----VHQPPPPPATLKVAEPP-------------PRP------- 1349

Query: 892  VPSAPPPKAQSVSPVQAPPPGGSAQLLPGKV-LVPLAAPSMSVRGGGAGQPLPLVSPPFS 950
             P  PPP  Q    V  PPP    +   G     P      + R    G   P  +P   
Sbjct: 1350 -PPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGR 1408

Query: 951  VPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSA 1010
                + A  P+K+ + T   +   + +   L    L GP  +P               +A
Sbjct: 1409 ARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPA------------ASAA 1456

Query: 1011 GGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPL---LAP 1067
             G   P   +P    A    S  P    A  F+S  P      + L SA  + L    AP
Sbjct: 1457 QGTGDPDWEAPGLPPAKRRKSESPDVDQA-SFSSDSPQDDTLTEHLQSAIDSILNLQQAP 1515

Query: 1068 GQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPS 1117
            G+      P+P  P A +A           G+PA  S  PL +P   PPS
Sbjct: 1516 GR-----TPAPSYPHAASA-----------GTPA--SPPPLHRPEAYPPS 1547



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 30/86 (34%), Positives = 34/86 (39%), Gaps = 21/86 (24%)

Query: 1529 PGAEAPL-PVPPPTGTAAAPA--------PTPSPAGGPDPTSPSSDSGTAQAAPPLPP-P 1578
            P +E PL P PPP      P           P PA  P PT+P          PP PP  
Sbjct: 813  PPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPG---------PPQPPLR 863

Query: 1579 PESGPGQPGWEGAPQPSPPPPGPSTA 1604
            P+S P  P     P P  PP   S+A
Sbjct: 864  PQSQP--PEGPLPPAPHLPPSSTSSA 887



 Score = 35.8 bits (81), Expect = 0.34
 Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 18/102 (17%)

Query: 1525 TEQPPGAEAP-LPVP-------PPTGTAAAPAPTPSPAGGPDPTSPSSDSGTA------Q 1570
            ++QP  AE P L VP       PP     APA   +   G  P +P S +  A       
Sbjct: 705  SQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPA 764

Query: 1571 AAPPLPPPPESGPGQPG----WEGAPQPSPPPPGPSTAATGR 1608
            AAP   P P S P  P      +    PSP P  P +    R
Sbjct: 765  AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR 806



 Score = 34.7 bits (78), Expect = 0.76
 Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 30/113 (26%)

Query: 1503 SKVCLQLKIREVR--QKIMQ--AATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPD 1558
            S++ L+LKI++     K++   A  P  QPP         PP  T     P P P   P 
Sbjct: 1304 SRIGLKLKIKQEAGLSKVVHNTALDPVHQPP---------PPPATLKVAEPPPRPPPPPP 1354

Query: 1559 PTSPSSDSGTAQAAPPLPP---PPESGPGQP------------GWEGAPQPSP 1596
            PT   +  GT    PP  P   P  + P  P            G  GAP+ +P
Sbjct: 1355 PTGQMN--GTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTP 1405



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 14/97 (14%)

Query: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTP---SPAGGPDPTSPSSDSG------TAQAAPP 1574
            PT+  P    P       G    P+      +P G   P +P++ +G      T Q AP 
Sbjct: 567  PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ 626

Query: 1575 LPP----PPESGPGQPGWEGAPQ-PSPPPPGPSTAAT 1606
             PP    P   G  QP  +  PQ P+P    P  A T
Sbjct: 627  APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATT 663



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 88/412 (21%), Positives = 132/412 (32%), Gaps = 103/412 (25%)

Query: 866  LPPGTSTNGKVLAATAPTPGIPILQSVPSA---PPPKAQSVSPVQAPPPGGSAQLLPGKV 922
            LP   S+ G  L    P  G P+  S P A   PPP   +   ++    GGS  +   + 
Sbjct: 1210 LPIAASSEGHRL----PGHG-PLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARA 1264

Query: 923  LVPLAAPSMSVRGGGA-----GQPLPLVSPP----------------------FSVPVQN 955
               L++ S S     +       P+P  + P                       S  V N
Sbjct: 1265 SSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHN 1324

Query: 956  GAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHAL 1015
             A  P   +   P P +T     PP  P   P PT Q        +  + +   A     
Sbjct: 1325 TALDP---VHQPPPPPATLKVAEPPPRPPPPPPPTGQ-------MNGTVDHPPPAAPERK 1374

Query: 1016 PLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPV 1075
            PLGT+P   +                             PL    +  +  PG       
Sbjct: 1375 PLGTAPHCPRL----------------------------PLRKTYRENVGGPG------- 1399

Query: 1076 PSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILP 1135
             +P+  PA  A GG         SPAP      A+  +A   L+  +A         +L 
Sbjct: 1400 -APEGTPAGRARGG---------SPAPLP----AKVDEATSGLIRELAAVEDELYQRML- 1444

Query: 1136 KGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPV--GSFE 1193
            KGPP    A+ A  +  P   A  +      P A+R   ++P   +A+ +S      +  
Sbjct: 1445 KGPPPEPAASAAQGTGDPDWEAPGL------PPAKRRKSESPDVDQASFSSDSPQDDTLT 1498

Query: 1194 AGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARS 1245
                            PG    P+ P +   G P  P P   PE + P++ +
Sbjct: 1499 EHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHN 1550



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 26/89 (29%), Positives = 30/89 (33%), Gaps = 3/89 (3%)

Query: 1518 IMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAG--GPDPTSPSSDSGTAQAAPPL 1575
            ++Q ATP     G  AP+    P   A     TP P G   P    P        AAPP 
Sbjct: 602  LVQPATPAAAT-GEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQ 660

Query: 1576 PPPPESGPGQPGWEGAPQPSPPPPGPSTA 1604
               P+  PG            PP    TA
Sbjct: 661  ATTPQPSPGLASSPEKIVLGQPPSATPTA 689



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 7/111 (6%)

Query: 45  APSQPDPSVQPSEAQQ-----PASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPG 99
           AP  P P ++P          PA H   S+ S   A S+  +   P         + PP 
Sbjct: 854 APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPS 913

Query: 100 ATCPESPGPGPP-HPLGVVESGKGPPPTTEEEASGP-PGEPRLDSETESDH 148
               +SP P P  H +    +   PPP T +  + P P  P+  +  E  H
Sbjct: 914 QGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFH 964


>gi|239747616 PREDICTED: similar to hCG1996386 [Homo sapiens]
          Length = 441

 Score =  120 bits (301), Expect = 1e-26
 Identities = 80/176 (45%), Positives = 93/176 (52%), Gaps = 14/176 (7%)

Query: 170 RTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKR--HRALVHQRHPNQDN 227
           + QSLSAL KE+DSSSEKDGRSPNK +KDHI  PM+      +        HQ HPNQDN
Sbjct: 60  QAQSLSALRKEQDSSSEKDGRSPNKWDKDHIWWPMSGSHNLQQAAPGPGRAHQGHPNQDN 119

Query: 228 RTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLG 287
           RT+S++L E WY LGP E QKY DLAFQVK AH +  P      K+ +      KP    
Sbjct: 120 RTISQMLSEQWYTLGPNEMQKY-DLAFQVKVAHLQQGP------KEVQLRGQAHKP---- 168

Query: 288 LAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHT 343
                  TR R        A P      L+        S  + P SS CGAERLHT
Sbjct: 169 -GASRSVTRARGSGAYQRWALPLPLGCPLNSCQLQPKHSRARIPRSSFCGAERLHT 223



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 43/72 (59%), Positives = 49/72 (68%)

Query: 1392 KKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLG 1451
            K R N TD+D   EDPT+P+ KMRR SSCS +PNTPK A C+GD F F  TG EAED L 
Sbjct: 347  KGRGNPTDMDPTLEDPTTPRCKMRRCSSCSPKPNTPKCAMCDGDSFPFACTGGEAEDRLR 406

Query: 1452 ELEYDKVPYSSL 1463
            E E +K   SSL
Sbjct: 407  EPETEKALSSSL 418



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 38/57 (66%), Positives = 39/57 (68%), Gaps = 1/57 (1%)

Query: 524 FGKGYGSAPSSSAS-SPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAG 579
           FGK YG   SSS + S ASSS  A TSF LG G FKAQESGQ S AGPLRP P G G
Sbjct: 266 FGKVYGPTLSSSYTYSDASSSTLAPTSFLLGPGAFKAQESGQDSRAGPLRPLPLGMG 322



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 24/49 (48%), Positives = 29/49 (59%), Gaps = 3/49 (6%)

Query: 21 MFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASN 69
          MFVW NVE  SVAVFPW+S +PFL P  P   ++PS+       P   N
Sbjct: 1  MFVWRNVEGHSVAVFPWYS-IPFLTP--PCSHMRPSKLPVTQWPPTREN 46


>gi|169162775 PREDICTED: similar to hCG1996386 [Homo sapiens]
          Length = 441

 Score =  120 bits (301), Expect = 1e-26
 Identities = 80/176 (45%), Positives = 93/176 (52%), Gaps = 14/176 (7%)

Query: 170 RTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKR--HRALVHQRHPNQDN 227
           + QSLSAL KE+DSSSEKDGRSPNK +KDHI  PM+      +        HQ HPNQDN
Sbjct: 60  QAQSLSALRKEQDSSSEKDGRSPNKWDKDHIWWPMSGSHNLQQAAPGPGRAHQGHPNQDN 119

Query: 228 RTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLG 287
           RT+S++L E WY LGP E QKY DLAFQVK AH +  P      K+ +      KP    
Sbjct: 120 RTISQMLSEQWYTLGPNEMQKY-DLAFQVKVAHLQQGP------KEVQLRGQAHKP---- 168

Query: 288 LAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHT 343
                  TR R        A P      L+        S  + P SS CGAERLHT
Sbjct: 169 -GASRSVTRARGSGAYQRWALPLPLGCPLNSCQLQPKHSRARIPRSSFCGAERLHT 223



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 43/72 (59%), Positives = 49/72 (68%)

Query: 1392 KKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLG 1451
            K R N TD+D   EDPT+P+ KMRR SSCS +PNTPK A C+GD F F  TG EAED L 
Sbjct: 347  KGRGNPTDMDPTLEDPTTPRCKMRRCSSCSPKPNTPKCAMCDGDSFPFACTGGEAEDRLR 406

Query: 1452 ELEYDKVPYSSL 1463
            E E +K   SSL
Sbjct: 407  EPETEKALSSSL 418



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 38/57 (66%), Positives = 39/57 (68%), Gaps = 1/57 (1%)

Query: 524 FGKGYGSAPSSSAS-SPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAG 579
           FGK YG   SSS + S ASSS  A TSF LG G FKAQESGQ S AGPLRP P G G
Sbjct: 266 FGKVYGPTLSSSYTYSDASSSTLAPTSFLLGPGAFKAQESGQDSRAGPLRPLPLGMG 322



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 24/49 (48%), Positives = 29/49 (59%), Gaps = 3/49 (6%)

Query: 21 MFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASN 69
          MFVW NVE  SVAVFPW+S +PFL P  P   ++PS+       P   N
Sbjct: 1  MFVWRNVEGHSVAVFPWYS-IPFLTP--PCSHMRPSKLPVTQWPPTREN 46


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score =  116 bits (291), Expect = 2e-25
 Identities = 226/925 (24%), Positives = 324/925 (35%), Gaps = 190/925 (20%)

Query: 515  PGPPD--PP--VAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGP 570
            PGPP   PP  V         P S    P S S +  T             +G G    P
Sbjct: 140  PGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTL------------AGPGGLFPP 187

Query: 571  LRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSV-IAAPPSGGGNILQ 629
                P  +GG ++P    RFLP         R  +     PP P++ + AP    G  L+
Sbjct: 188  RLADPVPSGGSSSP----RFLP---------RGNAPSPAPPPPPAISLNAPSYNWGAALR 234

Query: 630  TLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSST----PVP 685
            + ++P +          + S PAP  +   P+ P     +  +T    P S+     P P
Sbjct: 235  SSLVPSD----------LGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGP 284

Query: 686  IASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPGGSP-LGVSLVYSDKKSAAATSPA 741
             AS+P P S      P       GA T  G     PG  P L  SL+ +  K+     P 
Sbjct: 285  -ASQP-PVSSATMHLPLVLGPLGGAPTVEG-----PGAPPFLASSLLSAAAKAQHPPLPP 337

Query: 742  PHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPA-PPAVQFIAQGAPGGGTTAGSGAGAGS 800
            P  + G        + +  ++L    P    P  PP V  + +G        G      S
Sbjct: 338  PSTLQGRRPRAQAPSASHSSSL---RPSQRRPRRPPTVFRLLEGR-------GPQTPRRS 387

Query: 801  GPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAP----------GTKA 850
             P  P P  + QP +L +           P LP  L +   P P P          G+ A
Sbjct: 388  RPRAPAP--VPQPFSLPEPSQ--------PILPSVLSLLGLPTPGPSHSDGSFNLLGSDA 437

Query: 851  AAP--------SGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQS 902
              P        S P P   I+ +LP  TS +   L++    P  P     P  P P  QS
Sbjct: 438  HLPPPPTLSSGSPPQPRHPIQPSLPGTTSGS---LSSVPGAPAPPAASKAPVVPSPVLQS 494

Query: 903  VSPVQAPPPGGSAQLLP--GKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPP 960
             S       G +  L P  G    P  +P   +   GAG P  L + P  +P+  G  PP
Sbjct: 495  PSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALP--LPLSLGQPPP 552

Query: 961  SKIIQLTPVPVSTPSGLVPP----LSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALP 1016
            S ++  +   V T  G  PP    L P   PGP   P +   PS    + +       LP
Sbjct: 553  SPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLP 612

Query: 1017 LGTSPASSQAGT---VTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQ-APLLAPGQVGV 1072
              ++P S+   +   + + GPT+    G ++ G  GP+  +P    G  +PLL P     
Sbjct: 613  PPSAPPSNLLASFLPLLALGPTAGDGEG-SAEGAGGPSG-EPFSGLGDLSPLLFP----- 665

Query: 1073 SPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAAT 1132
             P+ +P  P   A     +       S  P     L+ P   PP+   +V T+TT P A+
Sbjct: 666  -PLSAP--PTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTS--SVTTATTDPGAS 720

Query: 1133 ILPKGPP---------------------APATATPA-------PTSPFPSATAGSMTYSL 1164
             L K P                      +  T++P        P  P  S   G     L
Sbjct: 721  SLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQL--L 778

Query: 1165 VAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELE 1224
                A  P  +A   +   + S+ +   +  A   P  +P   LEP P R P +  +   
Sbjct: 779  PGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838

Query: 1225 GQPTPPAPPPLPETWTPTARSS----------------PPLPPPAEERTSAKGPETMASK 1268
            G P PP P  L      T R S                   P    +  S + P  +A K
Sbjct: 839  GSPDPPVPELL------TGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALK 892

Query: 1269 F-------------PSSSSDWRVPGQGLENRGEPPTPPSPAPAP---AVAPGGSSESSSG 1312
            +             P  +  W+  G+  E   EP  PP P P      V PG   +S  G
Sbjct: 893  WGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRG 952

Query: 1313 RAAGDTPERKEAAGTGKKVKVRPPP 1337
            R     P R  +  + + + + P P
Sbjct: 953  RRRKYNPTR-NSNSSRQDITLEPSP 976



 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 128/479 (26%), Positives = 165/479 (34%), Gaps = 100/479 (20%)

Query: 502 SFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFS--LGSGTFKA 559
           S  H  PP       PP P            S S SS   + A  A S +  + S   ++
Sbjct: 435 SDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQS 494

Query: 560 QESGQGSTAGPLRPPPPGAGGPATP-SKATRFLPMDPATFRRKRPESVG--------GLE 610
              G G  AGP  P PP AGG A P     + L +  A F    P  +G        G  
Sbjct: 495 PSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF----PGMLGALPLPLSLGQP 550

Query: 611 PPGP----SVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSR 666
           PP P    S+      GGG      +LPP            P  P P LA G P  P   
Sbjct: 551 PPSPLLNHSLFGVLTGGGGQPPPEPLLPP------------PGGPGPPLAPGEPEGP--- 595

Query: 667 PAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVS 726
             + +V +++ P  S  +P  S P P++  A   P    G     G GS    G P G  
Sbjct: 596 --SLLVASLLPPPPSDLLPPPSAP-PSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEP 652

Query: 727 LVYSDKKSAAATSPA--PHLVAGPLLGTVGKAPATVTNLLVGT--PGYGAPAPPAVQFIA 782
                       SP   P L A P L  +  A      LL  T  P  G P  P V    
Sbjct: 653 F-----SGLGDLSPLLFPPLSAPPTLIALNSA------LLAATLDPPSGTPPQPCVLSAP 701

Query: 783 QGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGA--LGKAGGITQVQYILPTLPQQLQVAP 840
           Q  P               P   V      PGA  LGKA   +         P QL    
Sbjct: 702 QPGP---------------PTSSVTTATTDPGASSLGKAPSNS-------GRPPQLLSPL 739

Query: 841 APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKA 900
             A   G  ++  S P    S+    PPG   +G++     P  G         APPP +
Sbjct: 740 LGASLLGDLSSLTSSPGALPSL--LQPPGPLLSGQLGLQLLPGGG---------APPPLS 788

Query: 901 QSVSP-------VQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVP 952
           ++ SP       +Q PP    A  LP +      +P+ ++    A  PL  ++PP   P
Sbjct: 789 EASSPLACLLQSLQIPPEQPEAPCLPPE------SPASALEPEPARPPLSALAPPHGSP 841



 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 127/497 (25%), Positives = 168/497 (33%), Gaps = 92/497 (18%)

Query: 868  PGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLA 927
            PG   + ++    +P P        PSA PP      P   P  GG   L P    V  A
Sbjct: 126  PGEGASPQMFHTVSPGP--------PSARPPCRV---PPTTPLNGGPGSLPPEPPSVSQA 174

Query: 928  APSMSVRGG----GAGQPLPL--VSPPFSVPVQNG---AQPPSKIIQLTPVPVS------ 972
             P+++  GG        P+P    S P  +P  N    A PP   I L     +      
Sbjct: 175  FPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALR 234

Query: 973  ---TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQ-AGT 1028
                PS L  P +P     P S P   L   S  +T       + LP    PAS     +
Sbjct: 235  SSLVPSDLGSPPAPHASSSPPSDPP--LFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS 292

Query: 1029 VTSYGPTSSVALGF--TSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAA 1086
             T + P     LG   T  GP  P F+   L +  A    P      P+P P        
Sbjct: 293  ATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHP------PLPPPSTLQG-RR 345

Query: 1087 PGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATP 1146
            P     +A +S S  P+   P   P+      V+ +     P          PAP    P
Sbjct: 346  PRAQAPSASHSSSLRPSQRRPRRPPT------VFRLLEGRGPQTPRRSRPRAPAPV---P 396

Query: 1147 APTS-PFPSATAGSMTYSLVAPKAQRPSPKAPQ-KVKAAIASIPVGSFEAGASGRPGPAP 1204
             P S P PS        SL+      PS       +  + A +P       +SG P P P
Sbjct: 397  QPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPP--TLSSGSP-PQP 453

Query: 1205 RQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARS-----------SPPLPP-- 1251
            R P++P      +   S + G P PPA    P   +P  +S           + PLPP  
Sbjct: 454  RHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLA 513

Query: 1252 -------PAEER---TSAKGPETMASKFPSSSSDWRVPGQGLENR----------GEPP- 1290
                   P+ E+    S  G   M    P   S  + P   L N           G+PP 
Sbjct: 514  GGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPP 573

Query: 1291 ---TPPSPAPAPAVAPG 1304
                PP   P P +APG
Sbjct: 574  EPLLPPPGGPGPPLAPG 590



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 168/736 (22%), Positives = 243/736 (33%), Gaps = 156/736 (21%)

Query: 52  SVQPSE-AQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGP 110
           S+ PS+    PA H  +S  S  P    + A   PP          PP    P  PGP  
Sbjct: 236 SLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPP---------LPPSNNLPAHPGPAS 286

Query: 111 PHP-------LGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLP 163
             P       L +V    G  PT E    GP   P L S        + LS  +     P
Sbjct: 287 QPPVSSATMHLPLVLGPLGGAPTVE----GPGAPPFLAS--------SLLSAAAKAQHPP 334

Query: 164 LPPGK----RRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFS-------- 211
           LPP      RR ++      +  S+S      P++R     RRP   F +          
Sbjct: 335 LPPPSTLQGRRPRA------QAPSASHSSSLRPSQRRP---RRPPTVFRLLEGRGPQTPR 385

Query: 212 -KRHRALVHQRHPNQDNRTVSKILGEWWYALG-PKEKQKYHDLAFQV--KEAHFKAHPDW 267
             R RA      P         IL      LG P     + D +F +   +AH    P  
Sbjct: 386 RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTL 445

Query: 268 KWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSD 327
              +  + +      P    L G    T   S+S    A AP  +S+   V    +L S 
Sbjct: 446 SSGSPPQPRH-----PIQPSLPG----TTSGSLSSVPGAPAPPAASKA-PVVPSPVLQSP 495

Query: 328 TKAPGSSSCGAERLHTVGG------PGSARPRAFSHSGVHSLDG--------GEVDSQAL 373
           ++  G  +  A  L  + G      P   +  A S +G   + G        G+     L
Sbjct: 496 SEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPL 555

Query: 374 --QELTQMVSGPASYSGPKPSTQY-GAPGPFAAPG--EGGALAATGRPPLLPTRASRSQR 428
               L  +++G      P+P     G PGP  APG  EG +L      P  P+       
Sbjct: 556 LNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPS 615

Query: 429 AASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNK 488
           A   ++ +    ++           A DG G+ +             +G  SGE   G  
Sbjct: 616 APPSNLLASFLPLLAL------GPTAGDGEGSAE------------GAGGPSGEPFSGLG 657

Query: 489 GFGRKVFSP------VIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYG---SAPSSSASSP 539
                +F P      +I  +       LDP    PP P V      G   S+ +++ + P
Sbjct: 658 DLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDP 717

Query: 540 ASSSASAATSFS----------LGS---GTFKAQESGQGSTAGPLRPPPPGAGGPATPSK 586
            +SS   A S S          LG+   G   +  S  G+    L+PP P   G      
Sbjct: 718 GASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSG----QL 773

Query: 587 ATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGAR 646
             + LP              GG  PP  S  ++P +    +LQ+L +PP + E       
Sbjct: 774 GLQLLP--------------GGGAPPPLSEASSPLA---CLLQSLQIPPEQPE------- 809

Query: 647 VPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAG 706
                AP L   +PA+ L    A    + + P   +P P   +     G  +       G
Sbjct: 810 -----APCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGG 864

Query: 707 ARTEMGTGSRVPGGSP 722
            R   G      G  P
Sbjct: 865 LRGINGEARPARGRKP 880



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 29/86 (33%), Positives = 33/86 (38%), Gaps = 14/86 (16%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPP---- 1578
            T +  PP A  P  VPP T     P   P     P+P S S    T      L PP    
Sbjct: 137  TVSPGPPSARPPCRVPPTTPLNGGPGSLP-----PEPPSVSQAFPTLAGPGGLFPPRLAD 191

Query: 1579 --PESGPGQPGW---EGAPQPSPPPP 1599
              P  G   P +     AP P+PPPP
Sbjct: 192  PVPSGGSSSPRFLPRGNAPSPAPPPP 217



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 35/136 (25%), Positives = 51/136 (37%), Gaps = 17/136 (12%)

Query: 1483 FFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPL------- 1535
            F  S+  +AA +A++  + P      L+ R  R +   A+  +   P    P        
Sbjct: 318  FLASSLLSAAAKAQHPPLPPPST---LQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFR 374

Query: 1536 ------PVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWE 1589
                  P  P      APAP P P   P+P+ P   S  +    P P P  S  G     
Sbjct: 375  LLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHS-DGSFNLL 433

Query: 1590 GAPQPSPPPPGPSTAA 1605
            G+    PPPP  S+ +
Sbjct: 434  GSDAHLPPPPTLSSGS 449



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 10/73 (13%)

Query: 1530 GAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWE 1589
            G++A LP PPPT ++ +P   P P     P+ P + SG+  + P  P PP +       +
Sbjct: 434  GSDAHLP-PPPTLSSGSP---PQPRHPIQPSLPGTTSGSLSSVPGAPAPPAAS------K 483

Query: 1590 GAPQPSPPPPGPS 1602
                PSP    PS
Sbjct: 484  APVVPSPVLQSPS 496



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAA-PPLPPP 1578
            P  QPP + A + +P   G     APT    G P   + S  S  A+A  PPLPPP
Sbjct: 284  PASQPPVSSATMHLPLVLGPLGG-APTVEGPGAPPFLASSLLSAAAKAQHPPLPPP 338



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 16/134 (11%)

Query: 42  PFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGA- 100
           PFLA S    +   ++AQ P   P ++ Q + P   A  A            P RPP   
Sbjct: 317 PFLASSLLSAA---AKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVF 373

Query: 101 TCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE--------SDHDDAF 152
              E  GP  P         + P P  +  +   P +P L S             H D  
Sbjct: 374 RLLEGRGPQTPRR----SRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGS 429

Query: 153 LSIMSPEIQLPLPP 166
            +++  +  LP PP
Sbjct: 430 FNLLGSDAHLPPPP 443



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 32/99 (32%), Positives = 35/99 (35%), Gaps = 26/99 (26%)

Query: 1529 PGAEAPLPVPPPTGTAAAPAPT------------PSPAGGPDP----TSPSSDS-----G 1567
            P   AP P PPP    +  AP+            PS  G P      +SP SD       
Sbjct: 205  PRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCS 264

Query: 1568 TAQAAPPLPP----PPESGP-GQPGWEGAPQPSPPPPGP 1601
             A   PPLPP    P   GP  QP    A    P   GP
Sbjct: 265  DALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGP 303



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 34/111 (30%), Positives = 38/111 (34%), Gaps = 33/111 (29%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAP-------------TPSPAGGPDPTSPSSDSGTAQAA-- 1572
            PP    P P  PP+   A+  P             +   AGGP    P S  G       
Sbjct: 606  PPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSG-EPFSGLGDLSPLLF 664

Query: 1573 PPL--PP---------------PPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
            PPL  PP               PP   P QP    APQP PP    +TA T
Sbjct: 665  PPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATT 715



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 7/80 (8%)

Query: 1524 PTEQPPGAEAPLPVPP-----PTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPP 1578
            P   PPG   P P+ P     P+   A+  P P     P P++P S+   A   P L   
Sbjct: 575  PLLPPPGGPGP-PLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNL-LASFLPLLALG 632

Query: 1579 PESGPGQPGWEGAPQPSPPP 1598
            P +G G+   EGA  PS  P
Sbjct: 633  PTAGDGEGSAEGAGGPSGEP 652



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 32/102 (31%), Positives = 36/102 (35%), Gaps = 24/102 (23%)

Query: 1522 ATPTEQPPGAEAPL----PVPP---------PTGTAAAPAPTPSPAGGPDPTSPSSDSGT 1568
            A PT   PG   P     PVP          P G A +PAP P PA      +PS + G 
Sbjct: 174  AFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPA--ISLNAPSYNWGA 231

Query: 1569 A---------QAAPPLPPPPESGPGQPGWEGAPQPSPPPPGP 1601
            A           +PP P    S P  P          PPP P
Sbjct: 232  ALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLP 273



 Score = 32.3 bits (72), Expect = 3.8
 Identities = 29/95 (30%), Positives = 32/95 (33%), Gaps = 22/95 (23%)

Query: 1530 GAEAPLPVPPPTGTAAAPAPTP------SPAGGPDPTSPSSDSGTAQAAPPLP------- 1576
            GA    P+PP  G  A P P+P      S AG P          +    PP P       
Sbjct: 502  GAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLF 561

Query: 1577 ---------PPPESGPGQPGWEGAPQPSPPPPGPS 1602
                     PPPE     PG  G P     P GPS
Sbjct: 562  GVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPS 596


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  116 bits (290), Expect = 2e-25
 Identities = 206/949 (21%), Positives = 312/949 (32%), Gaps = 205/949 (21%)

Query: 509  PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQ---- 564
            P++P P  PP+   +          ++  +  +++ +  TS      T  A+E+      
Sbjct: 123  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182

Query: 565  -----GSTAGPLRPPPPGAG----GPA--TPSKATRFLPMDPATFRRKRPESVGGLEPPG 613
                   T+  L  P P A     GPA  TP + T   P +PA+   K P          
Sbjct: 183  SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT--------- 233

Query: 614  PSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVT 673
            P+ I + P+                         P  PAP+    AP  P   PA T   
Sbjct: 234  PTTIKSAPT------------------------TPKEPAPTTTKSAPTTP-KEPAPTTTK 268

Query: 674  NVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKK 733
                P  +TP     +P PT+ + E +P  T  A T      + P  +        + KK
Sbjct: 269  E---PAPTTP----KEPAPTTTK-EPAPTTTKSAPTT----PKEPAPT--------TPKK 308

Query: 734  SAAAT--SPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTT 791
             A  T   PAP     P   T  K PA  T           PAP   +  A  AP     
Sbjct: 309  PAPTTPKEPAPTTPKEPT-PTTPKEPAPTTK---------EPAPTTPKEPAPTAPKKPAP 358

Query: 792  AGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAA 851
                  A + P  P P    +P                PT P++        PAP T  +
Sbjct: 359  TTPKEPAPTTPKEPAPTTTKEPS---------------PTTPKE--------PAPTTTKS 395

Query: 852  APSG---PAPTTSIRFTLPPG--TSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPV 906
            AP+    PAPTT+      P   + T  K  A T P    P     P+   PK  + +  
Sbjct: 396  APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 455

Query: 907  QAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQL 966
            + P P  + +  P         P          +P P      + P +     P K+   
Sbjct: 456  KEPAPTTTKKPAP-------TTPK---------EPAP------TTPKETAPTTPKKLTPT 493

Query: 967  TPVPVSTPSGLVP-PLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQ 1025
            TP  ++  +   P P +P  L   T +      P                P  T+P ++ 
Sbjct: 494  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--------------PAPTTPKAAA 539

Query: 1026 AGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACA 1085
              T     PT+          P  PA   P                  P P+     A  
Sbjct: 540  PNTPKEPAPTT----------PKEPAPTTPK----------------EPAPTTPKETAPT 573

Query: 1086 APGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATAT 1145
             P G   T      PAPT+    A    AP +     +T+   PA T  PKG        
Sbjct: 574  TPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-PKGTAPTTPKE 630

Query: 1146 PAPTSP---FPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGP 1202
            PAPT+P    P+   G+   +L  P    P   AP+++       P  +     S +P P
Sbjct: 631  PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST----TSDKPAP 686

Query: 1203 APRQPLEPGPVREPTAPESELEGQPTPPAPPPLP-ETWTPTARSSPPLPPPAEERTSAKG 1261
               +   P   +EP     +     TP  PPP   E  TPT    P     + + ++   
Sbjct: 687  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST--- 743

Query: 1262 PETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPER 1321
            PE  A   P +          LEN  + P  P+     A  P  ++       A D    
Sbjct: 744  PELSAEPTPKA----------LENSPKEPGVPTTKTPAATKPEMTT------TAKDKTTE 787

Query: 1322 KEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLAT 1381
            ++   T +     P   K+T  + +    S++            +        TL++   
Sbjct: 788  RDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 847

Query: 1382 SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSA 1430
            +P+    +  KK   +T++ + PE+   PK +     + + +P  P  A
Sbjct: 848  APKV---TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA 893



 Score =  103 bits (257), Expect = 1e-21
 Identities = 129/556 (23%), Positives = 189/556 (33%), Gaps = 60/556 (10%)

Query: 1074 PVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATI 1133
            P P+    PA   P  P  T     +P  T SAP      AP +      T+   PA T 
Sbjct: 262  PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 321

Query: 1134 LPKGP-------PAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
             PK P       PAP T  PAPT+P   A          APK  +P+P  P++       
Sbjct: 322  -PKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APK--KPAPTTPKE------P 364

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPP-APPPLPETWTPTARS 1245
             P    E   +    P+P  P EP P    +AP +  E  PT   + P  P+  +PT   
Sbjct: 365  APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 424

Query: 1246 SP-PLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPG 1304
             P P  P     T+ K P     K P+ ++  + P      +  P TP  PAP     P 
Sbjct: 425  EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPAPTTTKKPAPTTPKEPAPT---TPK 480

Query: 1305 GSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPE 1364
             ++ ++  +    TPE+       K     P  L  T          E            
Sbjct: 481  ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 540

Query: 1365 FRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPED-----PTSPKRKMRRRSS 1419
              P+E  P+   +   T+P+    +  K+   +T   +AP       PT+PK K   +  
Sbjct: 541  NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-KPAPKEL 599

Query: 1420 CSSEPNTPKSAKCEGDIFTFDR-----TGTEAEDVLGELEYDKVPYSSLRRTLDQRRALV 1474
              +    P S  C+    T  +     T  E      +      P  +   TL +     
Sbjct: 600  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659

Query: 1475 MQLFQDHGFFPSAQA--TAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAE 1532
             +        P+     T+    + A   P +               + A  T + P   
Sbjct: 660  PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP--------KEPAPTTPKKPAPT 711

Query: 1533 APLPVPPPTGTAAAPAPTPSPAG---GPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWE 1589
             P   PP T   + P  T  P      PD ++P        +A P P   E+ P +PG  
Sbjct: 712  TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL------SAEPTPKALENSPKEPGVP 765

Query: 1590 GAPQPSPPPPGPSTAA 1605
                P+   P  +T A
Sbjct: 766  TTKTPAATKPEMTTTA 781



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 154/689 (22%), Positives = 222/689 (32%), Gaps = 88/689 (12%)

Query: 944  LVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTR 1003
            + +P  S    N      KI    P+    P   +PP S  +     +  ++  + +   
Sbjct: 99   VTTPDTSTTQHNKVSTSPKITTAKPI---NPRPSLPPNSDTSKETSLTVNKETTVETKET 155

Query: 1004 ITYVQSAGGHALPLGTSPASSQAGTVTS---YGPTSSVALGFTSLGPS---GPAFVQPLL 1057
             T  +          TS   +Q+   TS     PTS V    T    +   GPA   P  
Sbjct: 156  TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 215

Query: 1058 SAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPS 1117
                 P          P P+  +  A   P  P  T   S    P   AP      AP +
Sbjct: 216  PTPTTPKEPASTTPKEPTPTT-IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274

Query: 1118 LVYTVATSTTPPAATILPKGP-----PAPATAT-PAPTSPFPSATAGSMTYSLVAPKAQR 1171
                  T+T  PA T     P     PAP T   PAPT+P   A       +   PK   
Sbjct: 275  PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 334

Query: 1172 PSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPV--REPTAPESELEGQPTP 1229
            P+ K P          P    E   +    PAP  P EP P   +EP AP +  E  PT 
Sbjct: 335  PTTKEPA---------PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-APTTTKEPSPTT 384

Query: 1230 PAPP-PLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGE 1288
            P  P P      PT    P         T+ K P    +K P+ ++  + P      +  
Sbjct: 385  PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP-KEPAPTTPKKPA 443

Query: 1289 PPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNR 1348
            P TP  PAP     P   + +++ + A  TP  KE A T  K      P K T  +    
Sbjct: 444  PTTPKEPAPTTPKEP---APTTTKKPAPTTP--KEPAPTTPKETAPTTPKKLTPTT---- 494

Query: 1349 VLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPT 1408
                              PE++ P+   +   T+P  +  +  ++   +T  + AP   T
Sbjct: 495  ------------------PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP---T 533

Query: 1409 SPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLD 1468
            +PK         ++ PNTPK             T  E      +      P  +   TL 
Sbjct: 534  TPK---------AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 584

Query: 1469 QRRALVMQLFQDHGFFPSA--QATAAFQARYADIFPS-------KVCLQLKIREVRQKIM 1519
            +      +        P+   + T+    + A   P        K       +E      
Sbjct: 585  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 644

Query: 1520 QAATPT--EQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP 1577
            +   PT  ++P       P P          PT + +  P PT+P   + T         
Sbjct: 645  KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT-------- 696

Query: 1578 PPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
            P E  P  P       P  PPP  S  +T
Sbjct: 697  PKEPAPTTPKKPAPTTPETPPPTTSEVST 725



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 12/105 (11%)

Query: 46  PSQPDPSVQ---PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERP--PGA 100
           P +P P+     P+  ++PA           P E A    + P   T  + P  P  P  
Sbjct: 244 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303

Query: 101 TCPESPGPGPPH---PLGVVE----SGKGPPPTTEEEASGPPGEP 138
           T P+ P P  P    P    E    + K P PTT+E A   P EP
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 14/137 (10%)

Query: 46  PSQPDPSV----QPSEAQQPASHPVAS--NQSKEPAES---AAVAHERPPGGTGSADPE- 95
           P +P P+      P+  ++PA     S    +KEPA +   +A    + P  T + +P  
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428

Query: 96  ---RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE-SDHDDA 151
              + P  T P+ P P  P         +  P TT++ A   P EP   +  E +     
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 488

Query: 152 FLSIMSPEIQLPLPPGK 168
            L+  +PE   P  P K
Sbjct: 489 KLTPTTPEKLAPTTPEK 505



 Score = 35.0 bits (79), Expect = 0.59
 Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 6/95 (6%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERP--PGATCP 103
           P +P P+     A      P  +     P E      + P   T    P  P  P  T P
Sbjct: 298 PKEPAPTTPKKPAPTTPKEPAPTT----PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353

Query: 104 ESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEP 138
           + P P  P         +  P TT+E +   P EP
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 388



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 37/166 (22%), Positives = 56/166 (33%), Gaps = 29/166 (17%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE---------- 95
           P +P P+     A      P  +   K   +  A    + P  T S  P           
Sbjct: 636 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695

Query: 96  --RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFL 153
             + P  T P+ P P  P         + PPPTT E ++    +         D     L
Sbjct: 696 TPKEPAPTTPKKPAPTTP---------ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746

Query: 154 SIMSPEIQL---PLPPGKRRTQSLSALPKE-----RDSSSEKDGRS 191
           S       L   P  PG   T++ +A   E     +D ++E+D R+
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 36/159 (22%), Positives = 53/159 (33%), Gaps = 20/159 (12%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKE----PAESAAVAHERPPGGTGSADPERPPGAT 101
           P +P P+     A      P  +   K     P E A    + P   T      + P  T
Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT-----TKKPAPT 469

Query: 102 CPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQ 161
            P+ P P  P         K  P T E+ A   P +P   +  E       L+  +PE  
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE-------LAPTTPEEP 522

Query: 162 LPLPPGKRRTQSLSA----LPKERDSSSEKDGRSPNKRE 196
            P  P +    +  A     PKE   ++ K+      +E
Sbjct: 523 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  116 bits (290), Expect = 2e-25
 Identities = 206/949 (21%), Positives = 312/949 (32%), Gaps = 205/949 (21%)

Query: 509  PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQ---- 564
            P++P P  PP+   +          ++  +  +++ +  TS      T  A+E+      
Sbjct: 164  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223

Query: 565  -----GSTAGPLRPPPPGAG----GPA--TPSKATRFLPMDPATFRRKRPESVGGLEPPG 613
                   T+  L  P P A     GPA  TP + T   P +PA+   K P          
Sbjct: 224  SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT--------- 274

Query: 614  PSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVT 673
            P+ I + P+                         P  PAP+    AP  P   PA T   
Sbjct: 275  PTTIKSAPT------------------------TPKEPAPTTTKSAPTTP-KEPAPTTTK 309

Query: 674  NVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKK 733
                P  +TP     +P PT+ + E +P  T  A T      + P  +        + KK
Sbjct: 310  E---PAPTTP----KEPAPTTTK-EPAPTTTKSAPTT----PKEPAPT--------TPKK 349

Query: 734  SAAAT--SPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTT 791
             A  T   PAP     P   T  K PA  T           PAP   +  A  AP     
Sbjct: 350  PAPTTPKEPAPTTPKEPT-PTTPKEPAPTTK---------EPAPTTPKEPAPTAPKKPAP 399

Query: 792  AGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAA 851
                  A + P  P P    +P                PT P++        PAP T  +
Sbjct: 400  TTPKEPAPTTPKEPAPTTTKEPS---------------PTTPKE--------PAPTTTKS 436

Query: 852  APSG---PAPTTSIRFTLPPG--TSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPV 906
            AP+    PAPTT+      P   + T  K  A T P    P     P+   PK  + +  
Sbjct: 437  APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 496

Query: 907  QAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQL 966
            + P P  + +  P         P          +P P      + P +     P K+   
Sbjct: 497  KEPAPTTTKKPAP-------TTPK---------EPAP------TTPKETAPTTPKKLTPT 534

Query: 967  TPVPVSTPSGLVP-PLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQ 1025
            TP  ++  +   P P +P  L   T +      P                P  T+P ++ 
Sbjct: 535  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--------------PAPTTPKAAA 580

Query: 1026 AGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACA 1085
              T     PT+          P  PA   P                  P P+     A  
Sbjct: 581  PNTPKEPAPTT----------PKEPAPTTPK----------------EPAPTTPKETAPT 614

Query: 1086 APGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATAT 1145
             P G   T      PAPT+    A    AP +     +T+   PA T  PKG        
Sbjct: 615  TPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-PKGTAPTTPKE 671

Query: 1146 PAPTSP---FPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGP 1202
            PAPT+P    P+   G+   +L  P    P   AP+++       P  +     S +P P
Sbjct: 672  PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST----TSDKPAP 727

Query: 1203 APRQPLEPGPVREPTAPESELEGQPTPPAPPPLP-ETWTPTARSSPPLPPPAEERTSAKG 1261
               +   P   +EP     +     TP  PPP   E  TPT    P     + + ++   
Sbjct: 728  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST--- 784

Query: 1262 PETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPER 1321
            PE  A   P +          LEN  + P  P+     A  P  ++       A D    
Sbjct: 785  PELSAEPTPKA----------LENSPKEPGVPTTKTPAATKPEMTT------TAKDKTTE 828

Query: 1322 KEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLAT 1381
            ++   T +     P   K+T  + +    S++            +        TL++   
Sbjct: 829  RDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 888

Query: 1382 SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSA 1430
            +P+    +  KK   +T++ + PE+   PK +     + + +P  P  A
Sbjct: 889  APKV---TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA 934



 Score =  103 bits (257), Expect = 1e-21
 Identities = 129/556 (23%), Positives = 189/556 (33%), Gaps = 60/556 (10%)

Query: 1074 PVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATI 1133
            P P+    PA   P  P  T     +P  T SAP      AP +      T+   PA T 
Sbjct: 303  PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 362

Query: 1134 LPKGP-------PAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
             PK P       PAP T  PAPT+P   A          APK  +P+P  P++       
Sbjct: 363  -PKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APK--KPAPTTPKE------P 405

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPP-APPPLPETWTPTARS 1245
             P    E   +    P+P  P EP P    +AP +  E  PT   + P  P+  +PT   
Sbjct: 406  APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 465

Query: 1246 SP-PLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPG 1304
             P P  P     T+ K P     K P+ ++  + P      +  P TP  PAP     P 
Sbjct: 466  EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPAPTTTKKPAPTTPKEPAPT---TPK 521

Query: 1305 GSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPE 1364
             ++ ++  +    TPE+       K     P  L  T          E            
Sbjct: 522  ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 581

Query: 1365 FRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPED-----PTSPKRKMRRRSS 1419
              P+E  P+   +   T+P+    +  K+   +T   +AP       PT+PK K   +  
Sbjct: 582  NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK-KPAPKEL 640

Query: 1420 CSSEPNTPKSAKCEGDIFTFDR-----TGTEAEDVLGELEYDKVPYSSLRRTLDQRRALV 1474
              +    P S  C+    T  +     T  E      +      P  +   TL +     
Sbjct: 641  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700

Query: 1475 MQLFQDHGFFPSAQA--TAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAE 1532
             +        P+     T+    + A   P +               + A  T + P   
Sbjct: 701  PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP--------KEPAPTTPKKPAPT 752

Query: 1533 APLPVPPPTGTAAAPAPTPSPAG---GPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWE 1589
             P   PP T   + P  T  P      PD ++P        +A P P   E+ P +PG  
Sbjct: 753  TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL------SAEPTPKALENSPKEPGVP 806

Query: 1590 GAPQPSPPPPGPSTAA 1605
                P+   P  +T A
Sbjct: 807  TTKTPAATKPEMTTTA 822



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 154/689 (22%), Positives = 222/689 (32%), Gaps = 88/689 (12%)

Query: 944  LVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTR 1003
            + +P  S    N      KI    P+    P   +PP S  +     +  ++  + +   
Sbjct: 140  VTTPDTSTTQHNKVSTSPKITTAKPI---NPRPSLPPNSDTSKETSLTVNKETTVETKET 196

Query: 1004 ITYVQSAGGHALPLGTSPASSQAGTVTS---YGPTSSVALGFTSLGPS---GPAFVQPLL 1057
             T  +          TS   +Q+   TS     PTS V    T    +   GPA   P  
Sbjct: 197  TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 256

Query: 1058 SAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPS 1117
                 P          P P+  +  A   P  P  T   S    P   AP      AP +
Sbjct: 257  PTPTTPKEPASTTPKEPTPTT-IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315

Query: 1118 LVYTVATSTTPPAATILPKGP-----PAPATAT-PAPTSPFPSATAGSMTYSLVAPKAQR 1171
                  T+T  PA T     P     PAP T   PAPT+P   A       +   PK   
Sbjct: 316  PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 375

Query: 1172 PSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPV--REPTAPESELEGQPTP 1229
            P+ K P          P    E   +    PAP  P EP P   +EP AP +  E  PT 
Sbjct: 376  PTTKEPA---------PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP-APTTTKEPSPTT 425

Query: 1230 PAPP-PLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGE 1288
            P  P P      PT    P         T+ K P    +K P+ ++  + P      +  
Sbjct: 426  PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP-KEPAPTTPKKPA 484

Query: 1289 PPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNR 1348
            P TP  PAP     P   + +++ + A  TP  KE A T  K      P K T  +    
Sbjct: 485  PTTPKEPAPTTPKEP---APTTTKKPAPTTP--KEPAPTTPKETAPTTPKKLTPTT---- 535

Query: 1349 VLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPT 1408
                              PE++ P+   +   T+P  +  +  ++   +T  + AP   T
Sbjct: 536  ------------------PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP---T 574

Query: 1409 SPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLD 1468
            +PK         ++ PNTPK             T  E      +      P  +   TL 
Sbjct: 575  TPK---------AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 625

Query: 1469 QRRALVMQLFQDHGFFPSA--QATAAFQARYADIFPS-------KVCLQLKIREVRQKIM 1519
            +      +        P+   + T+    + A   P        K       +E      
Sbjct: 626  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 685

Query: 1520 QAATPT--EQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP 1577
            +   PT  ++P       P P          PT + +  P PT+P   + T         
Sbjct: 686  KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT-------- 737

Query: 1578 PPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
            P E  P  P       P  PPP  S  +T
Sbjct: 738  PKEPAPTTPKKPAPTTPETPPPTTSEVST 766



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 12/105 (11%)

Query: 46  PSQPDPSVQ---PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERP--PGA 100
           P +P P+     P+  ++PA           P E A    + P   T  + P  P  P  
Sbjct: 285 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344

Query: 101 TCPESPGPGPPH---PLGVVE----SGKGPPPTTEEEASGPPGEP 138
           T P+ P P  P    P    E    + K P PTT+E A   P EP
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 14/137 (10%)

Query: 46  PSQPDPSV----QPSEAQQPASHPVAS--NQSKEPAES---AAVAHERPPGGTGSADPE- 95
           P +P P+      P+  ++PA     S    +KEPA +   +A    + P  T + +P  
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469

Query: 96  ---RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE-SDHDDA 151
              + P  T P+ P P  P         +  P TT++ A   P EP   +  E +     
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 529

Query: 152 FLSIMSPEIQLPLPPGK 168
            L+  +PE   P  P K
Sbjct: 530 KLTPTTPEKLAPTTPEK 546



 Score = 35.0 bits (79), Expect = 0.59
 Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 6/95 (6%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERP--PGATCP 103
           P +P P+     A      P  +     P E      + P   T    P  P  P  T P
Sbjct: 339 PKEPAPTTPKKPAPTTPKEPAPTT----PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394

Query: 104 ESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEP 138
           + P P  P         +  P TT+E +   P EP
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 429



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 37/166 (22%), Positives = 56/166 (33%), Gaps = 29/166 (17%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE---------- 95
           P +P P+     A      P  +   K   +  A    + P  T S  P           
Sbjct: 677 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736

Query: 96  --RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFL 153
             + P  T P+ P P  P         + PPPTT E ++    +         D     L
Sbjct: 737 TPKEPAPTTPKKPAPTTP---------ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787

Query: 154 SIMSPEIQL---PLPPGKRRTQSLSALPKE-----RDSSSEKDGRS 191
           S       L   P  PG   T++ +A   E     +D ++E+D R+
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 36/159 (22%), Positives = 53/159 (33%), Gaps = 20/159 (12%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKE----PAESAAVAHERPPGGTGSADPERPPGAT 101
           P +P P+     A      P  +   K     P E A    + P   T      + P  T
Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT-----TKKPAPT 510

Query: 102 CPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQ 161
            P+ P P  P         K  P T E+ A   P +P   +  E       L+  +PE  
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE-------LAPTTPEEP 563

Query: 162 LPLPPGKRRTQSLSA----LPKERDSSSEKDGRSPNKRE 196
            P  P +    +  A     PKE   ++ K+      +E
Sbjct: 564 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  116 bits (290), Expect = 2e-25
 Identities = 206/949 (21%), Positives = 312/949 (32%), Gaps = 205/949 (21%)

Query: 509  PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQ---- 564
            P++P P  PP+   +          ++  +  +++ +  TS      T  A+E+      
Sbjct: 216  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 275

Query: 565  -----GSTAGPLRPPPPGAG----GPA--TPSKATRFLPMDPATFRRKRPESVGGLEPPG 613
                   T+  L  P P A     GPA  TP + T   P +PA+   K P          
Sbjct: 276  SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT--------- 326

Query: 614  PSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVT 673
            P+ I + P+                         P  PAP+    AP  P   PA T   
Sbjct: 327  PTTIKSAPT------------------------TPKEPAPTTTKSAPTTP-KEPAPTTTK 361

Query: 674  NVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKK 733
                P  +TP     +P PT+ + E +P  T  A T      + P  +        + KK
Sbjct: 362  E---PAPTTP----KEPAPTTTK-EPAPTTTKSAPTT----PKEPAPT--------TPKK 401

Query: 734  SAAAT--SPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTT 791
             A  T   PAP     P   T  K PA  T           PAP   +  A  AP     
Sbjct: 402  PAPTTPKEPAPTTPKEPT-PTTPKEPAPTTK---------EPAPTTPKEPAPTAPKKPAP 451

Query: 792  AGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAA 851
                  A + P  P P    +P                PT P++        PAP T  +
Sbjct: 452  TTPKEPAPTTPKEPAPTTTKEPS---------------PTTPKE--------PAPTTTKS 488

Query: 852  APSG---PAPTTSIRFTLPPG--TSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPV 906
            AP+    PAPTT+      P   + T  K  A T P    P     P+   PK  + +  
Sbjct: 489  APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 548

Query: 907  QAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQL 966
            + P P  + +  P         P          +P P      + P +     P K+   
Sbjct: 549  KEPAPTTTKKPAP-------TTPK---------EPAP------TTPKETAPTTPKKLTPT 586

Query: 967  TPVPVSTPSGLVP-PLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQ 1025
            TP  ++  +   P P +P  L   T +      P                P  T+P ++ 
Sbjct: 587  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--------------PAPTTPKAAA 632

Query: 1026 AGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACA 1085
              T     PT+          P  PA   P                  P P+     A  
Sbjct: 633  PNTPKEPAPTT----------PKEPAPTTPK----------------EPAPTTPKETAPT 666

Query: 1086 APGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATAT 1145
             P G   T      PAPT+    A    AP +     +T+   PA T  PKG        
Sbjct: 667  TPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-PKGTAPTTPKE 723

Query: 1146 PAPTSP---FPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGP 1202
            PAPT+P    P+   G+   +L  P    P   AP+++       P  +     S +P P
Sbjct: 724  PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST----TSDKPAP 779

Query: 1203 APRQPLEPGPVREPTAPESELEGQPTPPAPPPLP-ETWTPTARSSPPLPPPAEERTSAKG 1261
               +   P   +EP     +     TP  PPP   E  TPT    P     + + ++   
Sbjct: 780  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST--- 836

Query: 1262 PETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPER 1321
            PE  A   P +          LEN  + P  P+     A  P  ++       A D    
Sbjct: 837  PELSAEPTPKA----------LENSPKEPGVPTTKTPAATKPEMTT------TAKDKTTE 880

Query: 1322 KEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLAT 1381
            ++   T +     P   K+T  + +    S++            +        TL++   
Sbjct: 881  RDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 940

Query: 1382 SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSA 1430
            +P+    +  KK   +T++ + PE+   PK +     + + +P  P  A
Sbjct: 941  APKV---TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA 986



 Score =  103 bits (258), Expect = 1e-21
 Identities = 176/827 (21%), Positives = 268/827 (32%), Gaps = 87/827 (10%)

Query: 843  APAPGTKAAAPSGPAPT---TSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            +P    KA  PSG + T   T+ R   PP      KV+ +   T    + ++  S+    
Sbjct: 71   SPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSS 130

Query: 900  AQSVSP----VQAPPPGGSAQLLPGKVLV-----------PLAAPSMSVRGGGA--GQPL 942
            + S S     +++     + + L  K+ V           P   P +    G        
Sbjct: 131  SSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDF 190

Query: 943  PLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSST 1002
             + +P  S    N      KI    P+    P   +PP S  +     +  ++  + +  
Sbjct: 191  KVTTPDTSTTQHNKVSTSPKITTAKPI---NPRPSLPPNSDTSKETSLTVNKETTVETKE 247

Query: 1003 RITYVQSAGGHALPLGTSPASSQAGTVTS---YGPTSSVALGFTSLGPS---GPAFVQPL 1056
              T  +          TS   +Q+   TS     PTS V    T    +   GPA   P 
Sbjct: 248  TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 307

Query: 1057 LSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPP 1116
                  P          P P+  +  A   P  P  T   S    P   AP      AP 
Sbjct: 308  EPTPTTPKEPASTTPKEPTPTT-IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366

Query: 1117 SLVYTVATSTTPPAATILPKGP-----PAPATAT-PAPTSPFPSATAGSMTYSLVAPKA- 1169
            +      T+T  PA T     P     PAP T   PAPT+P   A       +   PK  
Sbjct: 367  TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 426

Query: 1170 ------------QRPSPKAPQKVKAAIASIPVGSF--EAGASGRPGPAPRQPLEPGPVRE 1215
                        + P+P AP+K        P  +   E   +    P+P  P EP P   
Sbjct: 427  APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 486

Query: 1216 PTAPESELEGQPTPP-APPPLPETWTPTARSSP-PLPPPAEERTSAKGPETMASKFPSSS 1273
             +AP +  E  PT   + P  P+  +PT    P P  P     T+ K P     K P+ +
Sbjct: 487  KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 546

Query: 1274 SDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKV 1333
            +  + P      +  P TP  PAP     P  ++ ++  +    TPE+       K    
Sbjct: 547  TP-KEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 602

Query: 1334 RPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKK 1393
             P  L  T          E              P+E  P+   +   T+P+    +  K+
Sbjct: 603  TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 662

Query: 1394 RKNSTDLDSAPED-----PTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDR-----TG 1443
               +T   +AP       PT+PK K   +    +    P S  C+    T  +     T 
Sbjct: 663  TAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 721

Query: 1444 TEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQA--TAAFQARYADIF 1501
             E      +      P  +   TL +      +        P+     T+    + A   
Sbjct: 722  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781

Query: 1502 PSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAG---GPD 1558
            P +               + A  T + P    P   PP T   + P  T  P      PD
Sbjct: 782  PKETAPTTP--------KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 833

Query: 1559 PTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAA 1605
             ++P        +A P P   E+ P +PG      P+   P  +T A
Sbjct: 834  ESTPEL------SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 874



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 119/532 (22%), Positives = 169/532 (31%), Gaps = 114/532 (21%)

Query: 1103 TSSAPLAQPSQAPPSLVYTVATSTTPPAATI----LPKGPPAPATATPAPTSPFPSATAG 1158
            TS+  LA  S+          T+T  PA T      P  P  PA+ TP   +P    +A 
Sbjct: 275  TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 334

Query: 1159 SMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTA 1218
            + T    AP   + +P  P++        P  + E   +    PAP    EP P    +A
Sbjct: 335  T-TPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387

Query: 1219 PESELEGQPTPPAPPP--LPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDW 1276
            P +  E  PT P  P    P+   PT    P    P E   + K P     K P+ ++  
Sbjct: 388  PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP- 446

Query: 1277 RVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPP 1336
                     +  P TP  PAP     P   + +++   +  TP+      T         
Sbjct: 447  --------KKPAPTTPKEPAPTTPKEP---APTTTKEPSPTTPKEPAPTTTKSAPTTTKE 495

Query: 1337 PLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKN 1396
            P   T  S                      P+E  P+ T +   T+P        K+   
Sbjct: 496  PAPTTTKSAPTT------------------PKEPSPTTTKEPAPTTP--------KEPAP 529

Query: 1397 STDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYD 1456
            +T    AP  P  P             P TPK         T     T  ++       +
Sbjct: 530  TTPKKPAPTTPKEPA------------PTTPKEP---APTTTKKPAPTTPKEPAPTTPKE 574

Query: 1457 KVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQ 1516
              P +  +                         T     + A   P K        E+  
Sbjct: 575  TAPTTPKK------------------------LTPTTPEKLAPTTPEKPAPTTP-EELAP 609

Query: 1517 KIMQAATPT--EQP----PGAEAP-LPVPPPTGTAAAPAPT----PSPAGGPDPTSPSSD 1565
               +  TPT  E+P    P A AP  P  P   T   PAPT    P+P   P  T+P++ 
Sbjct: 610  TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT-PKETAPTTP 668

Query: 1566 SGTAQAA--------PPLPPPPESGP---GQPGWEGAPQPSPPPPGPSTAAT 1606
             GTA           P  P P E  P    +P      +P+P  P  +   T
Sbjct: 669  KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 113/523 (21%), Positives = 161/523 (30%), Gaps = 74/523 (14%)

Query: 1097 SGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSAT 1156
            S SP  T++ P+      PP+   +  TS T    T + +      T     T      T
Sbjct: 206  STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV-ETKETTTTNKQTSTDGKEKTT 264

Query: 1157 AGSMTYSL-------VAPKAQ---RPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQ 1206
            +   T S+       +AP ++   +P+PKA    K    + P    E   +    PA   
Sbjct: 265  SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK---EPTPTTPKEPASTT 321

Query: 1207 PLEPGPVREPTAPESELEGQPTPP-APPPLPETWTPTARSSP-PLPPPAEERTSAKGPET 1264
            P EP P    +AP +  E  PT   + P  P+   PT    P P  P     T+ K P  
Sbjct: 322  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381

Query: 1265 MASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEA 1324
              +K  S+ +  + P      +  P TP  PAP     P  ++           P  KE 
Sbjct: 382  TTTK--SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA------PTTKEP 433

Query: 1325 AGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPR 1384
            A T  K      P K    +                E     P+E  P+ T +   T+P 
Sbjct: 434  APTTPKEPAPTAPKKPAPTTPK--------------EPAPTTPKEPAPTTTKEPSPTTP- 478

Query: 1385 AILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGT 1444
                    K    T   SAP     P       ++  S P TPK             T  
Sbjct: 479  --------KEPAPTTTKSAPTTTKEPAP-----TTTKSAPTTPKEPSPTTTKEPAPTTPK 525

Query: 1445 EAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSK 1504
            E      +      P      T  +                 A  T    A      P+ 
Sbjct: 526  EPAPTTPKKPAPTTPKEPAPTTPKE----------------PAPTTTKKPAPTTPKEPAP 569

Query: 1505 VCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPA-PTPSPAGGPDPTSPS 1563
               +       +K+         P   E P P  P       P  PTP+    P PT+P 
Sbjct: 570  TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629

Query: 1564 SDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
            + +      P    P E  P  P      +P+P  P  +   T
Sbjct: 630  AAAPNTPKEPAPTTPKEPAPTTP-----KEPAPTTPKETAPTT 667



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 12/105 (11%)

Query: 46  PSQPDPSVQ---PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERP--PGA 100
           P +P P+     P+  ++PA           P E A    + P   T  + P  P  P  
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396

Query: 101 TCPESPGPGPPH---PLGVVE----SGKGPPPTTEEEASGPPGEP 138
           T P+ P P  P    P    E    + K P PTT+E A   P EP
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 14/137 (10%)

Query: 46  PSQPDPSV----QPSEAQQPASHPVAS--NQSKEPAES---AAVAHERPPGGTGSADPE- 95
           P +P P+      P+  ++PA     S    +KEPA +   +A    + P  T + +P  
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521

Query: 96  ---RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE-SDHDDA 151
              + P  T P+ P P  P         +  P TT++ A   P EP   +  E +     
Sbjct: 522 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 581

Query: 152 FLSIMSPEIQLPLPPGK 168
            L+  +PE   P  P K
Sbjct: 582 KLTPTTPEKLAPTTPEK 598



 Score = 35.0 bits (79), Expect = 0.59
 Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 6/95 (6%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERP--PGATCP 103
           P +P P+     A      P  +     P E      + P   T    P  P  P  T P
Sbjct: 391 PKEPAPTTPKKPAPTTPKEPAPTT----PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446

Query: 104 ESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEP 138
           + P P  P         +  P TT+E +   P EP
Sbjct: 447 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 37/166 (22%), Positives = 56/166 (33%), Gaps = 29/166 (17%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE---------- 95
           P +P P+     A      P  +   K   +  A    + P  T S  P           
Sbjct: 729 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788

Query: 96  --RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFL 153
             + P  T P+ P P  P         + PPPTT E ++    +         D     L
Sbjct: 789 TPKEPAPTTPKKPAPTTP---------ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839

Query: 154 SIMSPEIQL---PLPPGKRRTQSLSALPKE-----RDSSSEKDGRS 191
           S       L   P  PG   T++ +A   E     +D ++E+D R+
Sbjct: 840 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 36/159 (22%), Positives = 53/159 (33%), Gaps = 20/159 (12%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKE----PAESAAVAHERPPGGTGSADPERPPGAT 101
           P +P P+     A      P  +   K     P E A    + P   T      + P  T
Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT-----TKKPAPT 562

Query: 102 CPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQ 161
            P+ P P  P         K  P T E+ A   P +P   +  E       L+  +PE  
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE-------LAPTTPEEP 615

Query: 162 LPLPPGKRRTQSLSA----LPKERDSSSEKDGRSPNKRE 196
            P  P +    +  A     PKE   ++ K+      +E
Sbjct: 616 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  116 bits (290), Expect = 2e-25
 Identities = 206/949 (21%), Positives = 312/949 (32%), Gaps = 205/949 (21%)

Query: 509  PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQ---- 564
            P++P P  PP+   +          ++  +  +++ +  TS      T  A+E+      
Sbjct: 257  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 316

Query: 565  -----GSTAGPLRPPPPGAG----GPA--TPSKATRFLPMDPATFRRKRPESVGGLEPPG 613
                   T+  L  P P A     GPA  TP + T   P +PA+   K P          
Sbjct: 317  SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT--------- 367

Query: 614  PSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVT 673
            P+ I + P+                         P  PAP+    AP  P   PA T   
Sbjct: 368  PTTIKSAPT------------------------TPKEPAPTTTKSAPTTP-KEPAPTTTK 402

Query: 674  NVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKK 733
                P  +TP     +P PT+ + E +P  T  A T      + P  +        + KK
Sbjct: 403  E---PAPTTP----KEPAPTTTK-EPAPTTTKSAPTT----PKEPAPT--------TPKK 442

Query: 734  SAAAT--SPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTT 791
             A  T   PAP     P   T  K PA  T           PAP   +  A  AP     
Sbjct: 443  PAPTTPKEPAPTTPKEPT-PTTPKEPAPTTK---------EPAPTTPKEPAPTAPKKPAP 492

Query: 792  AGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAA 851
                  A + P  P P    +P                PT P++        PAP T  +
Sbjct: 493  TTPKEPAPTTPKEPAPTTTKEPS---------------PTTPKE--------PAPTTTKS 529

Query: 852  APSG---PAPTTSIRFTLPPG--TSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPV 906
            AP+    PAPTT+      P   + T  K  A T P    P     P+   PK  + +  
Sbjct: 530  APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 589

Query: 907  QAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQL 966
            + P P  + +  P         P          +P P      + P +     P K+   
Sbjct: 590  KEPAPTTTKKPAP-------TTPK---------EPAP------TTPKETAPTTPKKLTPT 627

Query: 967  TPVPVSTPSGLVP-PLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQ 1025
            TP  ++  +   P P +P  L   T +      P                P  T+P ++ 
Sbjct: 628  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE--------------PAPTTPKAAA 673

Query: 1026 AGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACA 1085
              T     PT+          P  PA   P                  P P+     A  
Sbjct: 674  PNTPKEPAPTT----------PKEPAPTTPK----------------EPAPTTPKETAPT 707

Query: 1086 APGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATAT 1145
             P G   T      PAPT+    A    AP +     +T+   PA T  PKG        
Sbjct: 708  TPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-PKGTAPTTPKE 764

Query: 1146 PAPTSP---FPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGP 1202
            PAPT+P    P+   G+   +L  P    P   AP+++       P  +     S +P P
Sbjct: 765  PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST----TSDKPAP 820

Query: 1203 APRQPLEPGPVREPTAPESELEGQPTPPAPPPLP-ETWTPTARSSPPLPPPAEERTSAKG 1261
               +   P   +EP     +     TP  PPP   E  TPT    P     + + ++   
Sbjct: 821  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST--- 877

Query: 1262 PETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPER 1321
            PE  A   P +          LEN  + P  P+     A  P  ++       A D    
Sbjct: 878  PELSAEPTPKA----------LENSPKEPGVPTTKTPAATKPEMTT------TAKDKTTE 921

Query: 1322 KEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLAT 1381
            ++   T +     P   K+T  + +    S++            +        TL++   
Sbjct: 922  RDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 981

Query: 1382 SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSA 1430
            +P+    +  KK   +T++ + PE+   PK +     + + +P  P  A
Sbjct: 982  APKV---TTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA 1027



 Score =  103 bits (258), Expect = 1e-21
 Identities = 176/827 (21%), Positives = 268/827 (32%), Gaps = 87/827 (10%)

Query: 843  APAPGTKAAAPSGPAPT---TSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            +P    KA  PSG + T   T+ R   PP      KV+ +   T    + ++  S+    
Sbjct: 112  SPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSS 171

Query: 900  AQSVSP----VQAPPPGGSAQLLPGKVLV-----------PLAAPSMSVRGGGA--GQPL 942
            + S S     +++     + + L  K+ V           P   P +    G        
Sbjct: 172  SSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDF 231

Query: 943  PLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSST 1002
             + +P  S    N      KI    P+    P   +PP S  +     +  ++  + +  
Sbjct: 232  KVTTPDTSTTQHNKVSTSPKITTAKPI---NPRPSLPPNSDTSKETSLTVNKETTVETKE 288

Query: 1003 RITYVQSAGGHALPLGTSPASSQAGTVTS---YGPTSSVALGFTSLGPS---GPAFVQPL 1056
              T  +          TS   +Q+   TS     PTS V    T    +   GPA   P 
Sbjct: 289  TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 348

Query: 1057 LSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPP 1116
                  P          P P+  +  A   P  P  T   S    P   AP      AP 
Sbjct: 349  EPTPTTPKEPASTTPKEPTPTT-IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407

Query: 1117 SLVYTVATSTTPPAATILPKGP-----PAPATAT-PAPTSPFPSATAGSMTYSLVAPKA- 1169
            +      T+T  PA T     P     PAP T   PAPT+P   A       +   PK  
Sbjct: 408  TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP 467

Query: 1170 ------------QRPSPKAPQKVKAAIASIPVGSF--EAGASGRPGPAPRQPLEPGPVRE 1215
                        + P+P AP+K        P  +   E   +    P+P  P EP P   
Sbjct: 468  APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 527

Query: 1216 PTAPESELEGQPTPP-APPPLPETWTPTARSSP-PLPPPAEERTSAKGPETMASKFPSSS 1273
             +AP +  E  PT   + P  P+  +PT    P P  P     T+ K P     K P+ +
Sbjct: 528  KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 587

Query: 1274 SDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKV 1333
            +  + P      +  P TP  PAP     P  ++ ++  +    TPE+       K    
Sbjct: 588  TP-KEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 643

Query: 1334 RPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKK 1393
             P  L  T          E              P+E  P+   +   T+P+    +  K+
Sbjct: 644  TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 703

Query: 1394 RKNSTDLDSAPED-----PTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDR-----TG 1443
               +T   +AP       PT+PK K   +    +    P S  C+    T  +     T 
Sbjct: 704  TAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP 762

Query: 1444 TEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQA--TAAFQARYADIF 1501
             E      +      P  +   TL +      +        P+     T+    + A   
Sbjct: 763  KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822

Query: 1502 PSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAG---GPD 1558
            P +               + A  T + P    P   PP T   + P  T  P      PD
Sbjct: 823  PKETAPTTP--------KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD 874

Query: 1559 PTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAA 1605
             ++P        +A P P   E+ P +PG      P+   P  +T A
Sbjct: 875  ESTPEL------SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 915



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 119/532 (22%), Positives = 169/532 (31%), Gaps = 114/532 (21%)

Query: 1103 TSSAPLAQPSQAPPSLVYTVATSTTPPAATI----LPKGPPAPATATPAPTSPFPSATAG 1158
            TS+  LA  S+          T+T  PA T      P  P  PA+ TP   +P    +A 
Sbjct: 316  TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 375

Query: 1159 SMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTA 1218
            + T    AP   + +P  P++        P  + E   +    PAP    EP P    +A
Sbjct: 376  T-TPKEPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428

Query: 1219 PESELEGQPTPPAPPP--LPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDW 1276
            P +  E  PT P  P    P+   PT    P    P E   + K P     K P+ ++  
Sbjct: 429  PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP- 487

Query: 1277 RVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPP 1336
                     +  P TP  PAP     P   + +++   +  TP+      T         
Sbjct: 488  --------KKPAPTTPKEPAPTTPKEP---APTTTKEPSPTTPKEPAPTTTKSAPTTTKE 536

Query: 1337 PLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKN 1396
            P   T  S                      P+E  P+ T +   T+P        K+   
Sbjct: 537  PAPTTTKSAPTT------------------PKEPSPTTTKEPAPTTP--------KEPAP 570

Query: 1397 STDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYD 1456
            +T    AP  P  P             P TPK         T     T  ++       +
Sbjct: 571  TTPKKPAPTTPKEPA------------PTTPKEP---APTTTKKPAPTTPKEPAPTTPKE 615

Query: 1457 KVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQ 1516
              P +  +                         T     + A   P K        E+  
Sbjct: 616  TAPTTPKK------------------------LTPTTPEKLAPTTPEKPAPTTP-EELAP 650

Query: 1517 KIMQAATPT--EQP----PGAEAP-LPVPPPTGTAAAPAPT----PSPAGGPDPTSPSSD 1565
               +  TPT  E+P    P A AP  P  P   T   PAPT    P+P   P  T+P++ 
Sbjct: 651  TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT-PKETAPTTP 709

Query: 1566 SGTAQAA--------PPLPPPPESGP---GQPGWEGAPQPSPPPPGPSTAAT 1606
             GTA           P  P P E  P    +P      +P+P  P  +   T
Sbjct: 710  KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 113/523 (21%), Positives = 161/523 (30%), Gaps = 74/523 (14%)

Query: 1097 SGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSAT 1156
            S SP  T++ P+      PP+   +  TS T    T + +      T     T      T
Sbjct: 247  STSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV-ETKETTTTNKQTSTDGKEKTT 305

Query: 1157 AGSMTYSL-------VAPKAQ---RPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQ 1206
            +   T S+       +AP ++   +P+PKA    K    + P    E   +    PA   
Sbjct: 306  SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK---EPTPTTPKEPASTT 362

Query: 1207 PLEPGPVREPTAPESELEGQPTPP-APPPLPETWTPTARSSP-PLPPPAEERTSAKGPET 1264
            P EP P    +AP +  E  PT   + P  P+   PT    P P  P     T+ K P  
Sbjct: 363  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422

Query: 1265 MASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEA 1324
              +K  S+ +  + P      +  P TP  PAP     P  ++           P  KE 
Sbjct: 423  TTTK--SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA------PTTKEP 474

Query: 1325 AGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPR 1384
            A T  K      P K    +                E     P+E  P+ T +   T+P 
Sbjct: 475  APTTPKEPAPTAPKKPAPTTPK--------------EPAPTTPKEPAPTTTKEPSPTTP- 519

Query: 1385 AILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGT 1444
                    K    T   SAP     P       ++  S P TPK             T  
Sbjct: 520  --------KEPAPTTTKSAPTTTKEPAP-----TTTKSAPTTPKEPSPTTTKEPAPTTPK 566

Query: 1445 EAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSK 1504
            E      +      P      T  +                 A  T    A      P+ 
Sbjct: 567  EPAPTTPKKPAPTTPKEPAPTTPKE----------------PAPTTTKKPAPTTPKEPAP 610

Query: 1505 VCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPA-PTPSPAGGPDPTSPS 1563
               +       +K+         P   E P P  P       P  PTP+    P PT+P 
Sbjct: 611  TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 670

Query: 1564 SDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
            + +      P    P E  P  P      +P+P  P  +   T
Sbjct: 671  AAAPNTPKEPAPTTPKEPAPTTP-----KEPAPTTPKETAPTT 708



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 12/105 (11%)

Query: 46  PSQPDPSVQ---PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERP--PGA 100
           P +P P+     P+  ++PA           P E A    + P   T  + P  P  P  
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437

Query: 101 TCPESPGPGPPH---PLGVVE----SGKGPPPTTEEEASGPPGEP 138
           T P+ P P  P    P    E    + K P PTT+E A   P EP
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 14/137 (10%)

Query: 46  PSQPDPSV----QPSEAQQPASHPVAS--NQSKEPAES---AAVAHERPPGGTGSADPE- 95
           P +P P+      P+  ++PA     S    +KEPA +   +A    + P  T + +P  
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562

Query: 96  ---RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE-SDHDDA 151
              + P  T P+ P P  P         +  P TT++ A   P EP   +  E +     
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 622

Query: 152 FLSIMSPEIQLPLPPGK 168
            L+  +PE   P  P K
Sbjct: 623 KLTPTTPEKLAPTTPEK 639



 Score = 35.0 bits (79), Expect = 0.59
 Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 6/95 (6%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERP--PGATCP 103
           P +P P+     A      P  +     P E      + P   T    P  P  P  T P
Sbjct: 432 PKEPAPTTPKKPAPTTPKEPAPTT----PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 487

Query: 104 ESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEP 138
           + P P  P         +  P TT+E +   P EP
Sbjct: 488 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 37/166 (22%), Positives = 56/166 (33%), Gaps = 29/166 (17%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE---------- 95
           P +P P+     A      P  +   K   +  A    + P  T S  P           
Sbjct: 770 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829

Query: 96  --RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFL 153
             + P  T P+ P P  P         + PPPTT E ++    +         D     L
Sbjct: 830 TPKEPAPTTPKKPAPTTP---------ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880

Query: 154 SIMSPEIQL---PLPPGKRRTQSLSALPKE-----RDSSSEKDGRS 191
           S       L   P  PG   T++ +A   E     +D ++E+D R+
Sbjct: 881 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 36/159 (22%), Positives = 53/159 (33%), Gaps = 20/159 (12%)

Query: 46  PSQPDPSVQPSEAQQPASHPVASNQSKE----PAESAAVAHERPPGGTGSADPERPPGAT 101
           P +P P+     A      P  +   K     P E A    + P   T      + P  T
Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT-----TKKPAPT 603

Query: 102 CPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQ 161
            P+ P P  P         K  P T E+ A   P +P   +  E       L+  +PE  
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE-------LAPTTPEEP 656

Query: 162 LPLPPGKRRTQSLSA----LPKERDSSSEKDGRSPNKRE 196
            P  P +    +  A     PKE   ++ K+      +E
Sbjct: 657 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  116 bits (290), Expect = 2e-25
 Identities = 115/434 (26%), Positives = 158/434 (36%), Gaps = 63/434 (14%)

Query: 831  TLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAP----TPGI 886
            T P      P+P P   T     + P+P T+   T PP T+ +  +   T P    TP  
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 887  PILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVS 946
            PI  S  + PPP      P   P P             P   PS          P    S
Sbjct: 1457 PI--STTTTPPPTTTPSPPTTTPSP-------------PTTTPSPPTTTTTTPPPTTTPS 1501

Query: 947  PPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITY 1006
            PP + P+     PP+    L   P +TPS   PP +  T P PT+ P     P++T IT 
Sbjct: 1502 PPTTTPI----TPPASTTTLP--PTTTPS---PPTTTTTTPPPTTTPSP---PTTTPITP 1549

Query: 1007 VQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
              S     LP  T+P  S   T T+  P ++     T+  PS P     + +    P   
Sbjct: 1550 PTST--TTLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPPT----ITTTTPPPTTT 1601

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P      P  +   PP    P  P  T      P  T++ P       PP+   T   +T
Sbjct: 1602 PS----PPTTTTTTPPPTTTPSPPTTTPI--TPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1655

Query: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
            TP   T     PP   T TP PT+  PS+   + T S        PSP           +
Sbjct: 1656 TPSPPTTTTPSPPITTTTTPPPTTT-PSSPI-TTTPSPPTTTMTTPSPTTTPSSPITTTT 1713

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQP---------TPPAPPPL-P 1236
             P       ++  P P P     P P   P+ P + +   P         T P PP + P
Sbjct: 1714 TP------SSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP 1767

Query: 1237 ETWTPTARSSPPLP 1250
             T++P + ++P  P
Sbjct: 1768 PTFSPFSTTTPTTP 1781



 Score =  103 bits (258), Expect = 1e-21
 Identities = 178/825 (21%), Positives = 255/825 (30%), Gaps = 137/825 (16%)

Query: 512  PEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPL 571
            P P   P PP+          S++ + P +++ S  T+      T  +  +   +T  P 
Sbjct: 1448 PPPTTTPSPPI----------STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT 1497

Query: 572  RPPPPGAGGPATPSKATRFLP----MDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNI 627
              P P    P TP  +T  LP      P T     P       PP  + I  P S     
Sbjct: 1498 TTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS----- 1552

Query: 628  LQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAAT-----MVTNVVRPVSST 682
              T  LPP            PS P  +     P    S P  T      +T    P ++T
Sbjct: 1553 --TTTLPP---------TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601

Query: 683  PVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAP 742
            P P  +           SP  T        T +  P  +P               T+P P
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP--------SPPPTTTTTPPP 1653

Query: 743  HLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGP 802
                 P   T    P T T      P    P+ P         P   TT  +     + P
Sbjct: 1654 TTTPSPPTTTTPSPPITTTTT---PPPTTTPSSPITT-----TPSPPTTTMTTPSPTTTP 1705

Query: 803  NGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSI 862
            + P                      I  T        P+P P   T  +  + P+P T+ 
Sbjct: 1706 SSP----------------------ITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743

Query: 863  RFTLPPGTSTNGKVLAATAPTPGI------PILQSVPSAP-PPKAQSVSPVQA-----PP 910
              TLPP  +T    L  T   P I      P   + P+ P  P       + +       
Sbjct: 1744 MTTLPP--TTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHK 1801

Query: 911  PGGSAQLLPGKVLVPLAAPSMSVRG--------GGAGQ------------------PLPL 944
            PGG  +L+ G V  P  A ++S R         G  GQ                  P  +
Sbjct: 1802 PGGDTELI-GDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860

Query: 945  VSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVP----PLSPATLPGPTSQPQKVLLPS 1000
            +   F +  +   Q    + Q T +  +T     P    P++  T   PT  P     P+
Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT 1920

Query: 1001 STRITYVQSAGGHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPSGPAFVQP 1055
            +T IT   +      P GT +P ++   T T+      PT +     T +  +      P
Sbjct: 1921 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1980

Query: 1056 LLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAP 1115
              +  Q P   P     +  P+P  P     P    IT   + +P PT +    Q     
Sbjct: 1981 TPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTTT 2037

Query: 1116 PSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPK 1175
            P    T  T T  P  T  P   P   T T  PT P P+ T    T  +       P+P 
Sbjct: 2038 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPT 2096

Query: 1176 APQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP 1233
                       I   +     +  P P   Q     P+   T   P     G  TP   P
Sbjct: 2097 PTGTQTPTTTPI---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153

Query: 1234 -----PLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
                  +  T TPT   +P   P     T    P    ++ P+++
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2198



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 160/698 (22%), Positives = 211/698 (30%), Gaps = 140/698 (20%)

Query: 955  NGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHA 1014
            N   P  K I     P +TPS   PP S  TLP PT+ P     P++T  T         
Sbjct: 1387 NCCWPMDKCITTPSPPTTTPSP--PPTSTTTLP-PTTTPSP---PTTTTTT--------- 1431

Query: 1015 LPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSP 1074
             P  T+  S    T T+  PT+      T   P       P  +    P   P     +P
Sbjct: 1432 -PPPTTTPSPPITTTTTPPPTT------TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTP 1484

Query: 1075 VP---SPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAA 1131
             P   +   PP    P  P  T      PA T++ P       P +   T   +TTP   
Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTTPITP--PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542

Query: 1132 TILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGS 1191
            T  P  PP   T  P  T+P P  T  +       P     +  +P  +           
Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP----- 1597

Query: 1192 FEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPP--- 1248
                 +  P P       P P   P+ P +      TP  PP    T  PT   SPP   
Sbjct: 1598 ----PTTTPSPPTTTTTTPPPTTTPSPPTT------TPITPPTSTTTLPPTTTPSPPPTT 1647

Query: 1249 --LPPPAEERTSAKGPETMASKFP-----SSSSDWRVPGQGLENRGEPPTPPSPAPAPAV 1301
               PPP    T+   P T  +  P     ++      P   +     PPT     P+P  
Sbjct: 1648 TTTPPP----TTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT 1703

Query: 1302 APGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAE 1361
             P     +++  ++  TP               PPP   T  S                 
Sbjct: 1704 TPSSPITTTTTPSSTTTPS--------------PPPTTMTTPS----------------- 1732

Query: 1362 LPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPT-SPKRKMRRRSSC 1420
                      PSP   ++ T P     S       +T L  +   PT SP       + C
Sbjct: 1733 ------PTTTPSPPTTTMTTLPPTTTSS----PLTTTPLPPSITPPTFSPFSTTTPTTPC 1782

Query: 1421 -----------SSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTL-- 1467
                       S +PN  K       I      G  A        Y  VP   L +T+  
Sbjct: 1783 VPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVC 1842

Query: 1468 DQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQ 1527
            D    L+    ++    P      AF   Y        C       V Q      T TE 
Sbjct: 1843 DVSVGLIC---KNEDQKPGGVIPMAFCLNYEINVQCCEC-------VTQPTTMTTTTTEN 1892

Query: 1528 P-PGAEAPL-------PVPPPTG----------TAAAPAPTPSPAGGPDPTSPSSDSGTA 1569
            P P    P+       P P PTG          T     PTP+P G   PT+    + T 
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952

Query: 1570 QAAPPLPPPPESGPGQP-GWEGAPQPSPPPPGPSTAAT 1606
                P P   ++    P        P+P P G  T  T
Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1990



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 186/892 (20%), Positives = 268/892 (30%), Gaps = 154/892 (17%)

Query: 508  PPLDPEPPGP-PDPPVAFGKGYG--SAPSSSASSPASSSASAATSFSLGSGTFKAQESGQ 564
            P   P PP   P PP          + PS   ++P +  AS  T   L   T  +  +  
Sbjct: 1473 PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT---LPPTTTPSPPTTT 1529

Query: 565  GSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGG 624
             +T  P   P P    P TP  +T  LP  P T     P +      P P+   +PP+  
Sbjct: 1530 TTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTT---TTPPPTTTPSPPT-- 1582

Query: 625  GNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVT----NVVRPVS 680
                 T   PP            PS P  +     P    S P  T +T        P +
Sbjct: 1583 ----TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638

Query: 681  STPVP---------------------------IASKPFPTSGRAEASPNDTAGARTEMGT 713
            +TP P                             + P PT+  +       +   T M T
Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTT 1698

Query: 714  GSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLL----VGTPG 769
             S  P  +P       +   S    SP P  +  P   T    P T    L      +P 
Sbjct: 1699 PS--PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPL 1756

Query: 770  YGAPAPPAVQ------------------------FIAQGAPG----GGTTAGSGAGAGSG 801
               P PP++                         ++  G P     GG T   G   G G
Sbjct: 1757 TTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPG 1816

Query: 802  ------------PNGP-----------VPLGILQPGALGKAGGITQVQYIL--------- 829
                        P+ P           V +G++      K GG+  + + L         
Sbjct: 1817 WAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCC 1876

Query: 830  --PTLPQQLQVAPAPAPAP------GTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATA 881
               T P  +       P P       T       P PT +   T  P T+T         
Sbjct: 1877 ECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVT 1931

Query: 882  PTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQ 940
            PTP     Q+  + P     +V+P   P    +    P      +   P+ +        
Sbjct: 1932 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1991

Query: 941  PLPLVSPPFSVPVQNGAQPP-------SKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQP 993
            P+   +     P   G Q P       +  +  TP P  T +    P++  T   PT  P
Sbjct: 1992 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2051

Query: 994  QKVLLPSSTRITYVQSAGGHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPS 1048
                 P++T IT   +      P GT +P ++   T T+      PT +     T +  +
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2111

Query: 1049 GPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPL 1108
                  P  +  Q P   P     +  P+P  P     P    IT   + +P PT +   
Sbjct: 2112 TTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG-- 2168

Query: 1109 AQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPK 1168
             Q     P    T  T T  P  T  P   P   T T  PT P P+ T    T  +    
Sbjct: 2169 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT 2227

Query: 1169 AQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQ 1226
               P+P            I   +     +  P P   Q     P+   T   P     G 
Sbjct: 2228 TVTPTPTPTGTQTPTTTPI---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2284

Query: 1227 PTPPAPP-----PLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
             TP   P      +  T TPT   +P   P     T    P    ++ P+++
Sbjct: 2285 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 91/380 (23%), Positives = 124/380 (32%), Gaps = 35/380 (9%)

Query: 941  PLPLVSPPFSVPVQNGAQPPSKI------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQ 994
            P P  + P   P      PP+           TP P +TPS   PP++  T P PT+ P 
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPS---PPITTTTTPPPTTTPS 1455

Query: 995  KVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQ 1054
                P ST  T   +      P  T+P+     T T   PT++      +  PS P    
Sbjct: 1456 P---PISTTTTPPPTTTPS--PPTTTPSPP---TTTPSPPTTTTTTPPPTTTPSPPT-TT 1506

Query: 1055 PLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQA 1114
            P+        L P      P  +   PP    P  P  T      P  T++ P       
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP--PTSTTTLPPTTTPSP 1564

Query: 1115 PPSLVYTVATSTTPPAATILPKGPPAPATATPAPTS-PFPSATAGSMTYSLVAPKAQRPS 1173
            PP+   T   +TTP   T     PP   T TP PT+ P P  T  +       P     +
Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624

Query: 1174 PKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQP----TP 1229
            P  P          P  +     +  P P P     P P   P+ P +     P    T 
Sbjct: 1625 PITP----------PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT 1674

Query: 1230 PAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEP 1289
            P P   P +   T  S P         T+        +  PSS++    P   +      
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734

Query: 1290 PTPPSPAPAPAVAPGGSSES 1309
             TP  P       P  ++ S
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSS 1754



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 136/634 (21%), Positives = 199/634 (31%), Gaps = 72/634 (11%)

Query: 660  PAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPG 719
            P  P + P  T  T     V+ TP P  ++  PT+     +   T    T   TG++ P 
Sbjct: 1893 PTPPTTTPITTTTT-----VTPTPTPTGTQT-PTTTPITTTTTVTP---TPTPTGTQTPT 1943

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 1944 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 1990

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 1991 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 2033

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 2034 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 2087

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
              +V+P   P    +    P      +   P+ +        P+   +     P   G Q
Sbjct: 2088 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2147

Query: 959  PPSKI-------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAG 1011
             P+         +  TP P  T +    P++  T   PT  P     P++T IT   +  
Sbjct: 2148 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2207

Query: 1012 GHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                P GT +P ++   T T+      PT +     T +  +      P  +  Q P   
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2267

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     +  P+P  P     P    IT   + +P PT +    Q     P    T  T T
Sbjct: 2268 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPT 2324

Query: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
              P  T  P   P   T T  PT P P+ T    T  +       P+P            
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP-----PLPETW 1239
            I   +     +  P P   Q     P+   T   P     G  TP   P      +  T 
Sbjct: 2384 I---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440

Query: 1240 TPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
            TPT   +P   P     T    P    ++ P+++
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2474



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 152/718 (21%), Positives = 224/718 (31%), Gaps = 137/718 (19%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 3749 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3806

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 3807 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 3853

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 3854 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 3896

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 3897 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 3950

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
              +V+P   P    +    P      +   P+ +        P+   +     P   G Q
Sbjct: 3951 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4010

Query: 959  PPSKI-------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAG 1011
             P+         +  TP P  T +    P++  T   PT  P     P++T IT   +  
Sbjct: 4011 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4070

Query: 1012 GHALPLGT-SPASSQAGTVTSYGPT----SSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                P GT +P ++   T T+  PT     +     T +  +      P  +  Q P   
Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     +  P+P  P     P    IT   + +P PT +      +Q P +   T  T+ 
Sbjct: 4131 PITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTG-----TQTPTTTPITTTTTV 4184

Query: 1127 TP-PAATILPKGPPA----------------PATATPAPTSPFPSATAGSMTYSLVAPKA 1169
            TP P  T    GPP                 P ++TP  +    S    S T     P A
Sbjct: 4185 TPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPA 4244

Query: 1170 QRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTP 1229
               +  AP     A  +   G                 L P P    + P +   G  T 
Sbjct: 4245 IEMTSTAPPSTPTAPTTTSGG---------------HTLSPPPSTTTSPPGTPTRGTTTG 4289

Query: 1230 PAPPPLPET--------WTPTARSSPPLPPPAEERTSAKGPETMASKFPSS-------SS 1274
             +  P P T        WTPT     PL  P+  RT+   P      +PSS       + 
Sbjct: 4290 SSSAPTPSTVQTTTTSAWTPT---PTPLSTPSIIRTTGLRP------YPSSVLICCVLND 4340

Query: 1275 DWRVPGQGLEN---------------------RGEPPTPPSPAPAPAVAPGGSSESSS 1311
             +  PG+ + N                         P+ PSP P P+ +    S+ SS
Sbjct: 4341 TYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSS 4398



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 146/698 (20%), Positives = 214/698 (30%), Gaps = 126/698 (18%)

Query: 664  LSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPL 723
            ++ P+    T    P S+T +P  + P P +      P  T  +              P+
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPS-------------PPI 1442

Query: 724  GVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQ 783
                          T+P P     P + T    P T T     +P    P+PP       
Sbjct: 1443 -----------TTTTTPPPTTTPSPPISTTTTPPPTTT----PSPPTTTPSPPTT----- 1482

Query: 784  GAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPA 843
              P   TT  +     + P+ P    I  P     A   T      P+ P      P P 
Sbjct: 1483 -TPSPPTTTTTTPPPTTTPSPPTTTPITPP-----ASTTTLPPTTTPSPPTTTTTTPPPT 1536

Query: 844  PAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGI---PILQSVPSAPPPKA 900
              P      P  P  +T+   TLPP T+ +      T P P     P   + PS P    
Sbjct: 1537 TTPSPPTTTPITPPTSTT---TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITT 1593

Query: 901  QSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPP 960
             +  P   P P  +    P     P    +  +    +   LP  + P   P      PP
Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653

Query: 961  SKIIQLTPVP--VSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLG 1018
            +     TP P   +TPS   PP++  T P PT+ P                      P+ 
Sbjct: 1654 T----TTPSPPTTTTPS---PPITTTTTPPPTTTPSS--------------------PIT 1686

Query: 1019 TSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSP 1078
            T+P S    T+T+  PT++         PS P       S+   P         SP P+ 
Sbjct: 1687 TTP-SPPTTTMTTPSPTTT---------PSSPITTTTTPSSTTTP---------SPPPTT 1727

Query: 1079 QLPPACAAPGGPVITAFYSGSPAPTSS----APLAQPSQAPPSLVYTVATSTTPPAATI- 1133
               P+      P  T   +  P  TSS     PL  PS  PP+      T+ T P   + 
Sbjct: 1728 MTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL-PPSITPPTFSPFSTTTPTTPCVPLC 1786

Query: 1134 -----LPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKA-QRPSPKAPQKVKAAIASI 1187
                 L  G   P    P   +       G    + ++ +A   P     Q  +  +  +
Sbjct: 1787 NWTGWLDSG--KPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDV 1844

Query: 1188 PVGSFEAGASGRPGPAPRQPLEPG---------PVREPTAPESELEGQPTPPAPPPLPET 1238
             VG        +PG                    V +PT   +     PTPP   P+  T
Sbjct: 1845 SVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTT 1904

Query: 1239 WTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPA 1298
             T T     P P P   +T    P T  +    + +       G +     P   +    
Sbjct: 1905 TTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVT 1954

Query: 1299 PAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPP 1336
            P   P G+   ++      T        TG +     P
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 163/744 (21%), Positives = 226/744 (30%), Gaps = 163/744 (21%)

Query: 611  PPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAAT 670
            P  P+   +PP        T  LPP             + P+P         P + P+  
Sbjct: 1399 PSPPTTTPSPPP-----TSTTTLPPT------------TTPSPPTTTTTTPPPTTTPSPP 1441

Query: 671  MVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYS 730
            + T    P ++TP P      P S      P  T    T   T    P  +P        
Sbjct: 1442 ITTTTTPPPTTTPSP------PISTTTTPPPTTTPSPPT---TTPSPPTTTP-------- 1484

Query: 731  DKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGT 790
               +   T+P P     P   T    PA+ T L    P    P+PP             T
Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTL----PPTTTPSPP-------------T 1527

Query: 791  TAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKA 850
            T  +     + P+ P    I  P         T    + PT          P+P P T  
Sbjct: 1528 TTTTTPPPTTTPSPPTTTPITPP---------TSTTTLPPTT--------TPSPPPTTTT 1570

Query: 851  AAP----------SGPAPTTSIRFTLPPGTSTNGKVLAATAP----TPGIPILQSVPSAP 896
              P          + P+P T    T PP T+ +      T P    TP  P   + P  P
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP--TTTPITP 1628

Query: 897  PPKAQSVSPVQAPPPGGSAQLLPGKVLVP----LAAPSMSVRGGGAGQPLPLVSPPFSVP 952
            P    ++ P   P P  +    P     P       PS  +       P P  +P  S P
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT--TTTTPPPTTTP--SSP 1684

Query: 953  VQNGAQPPSKIIQLTPVPVSTPSGLV-------------PPLSPATLPGPTSQPQKVLLP 999
            +     PP+  +  TP P +TPS  +             PP +  T P PT+ P     P
Sbjct: 1685 ITTTPSPPTTTM-TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSP---P 1740

Query: 1000 SSTRITYVQSAGGHAL------PLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFV 1053
            ++T  T   +     L      P  T P  S   T T   P   +      L    P F 
Sbjct: 1741 TTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFH 1800

Query: 1054 QP-------------------LLSAGQAPLLAPGQVGVSPVPSPQLPPAC----AAPGGP 1090
            +P                      A   P +  GQ+G + V    +   C      PGG 
Sbjct: 1801 KPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860

Query: 1091 VITAFYSG----------SPAPTSSAPLAQPSQAPPSLV-YTVATSTTP---PAATILPK 1136
            +  AF                PT+       +  PP+    T  T+ TP   P  T  P 
Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT 1920

Query: 1137 GPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGA 1196
              P   T T  PT P P+ T    T  +       P+P            I   +     
Sbjct: 1921 TTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI---TTTTTV 1976

Query: 1197 SGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP-----PLPETWTPTARSSPPL 1249
            +  P P   Q     P+   T   P     G  TP   P      +  T TPT   +P  
Sbjct: 1977 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2036

Query: 1250 PPPAEERTSAKGPETMASKFPSSS 1273
             P     T    P    ++ P+++
Sbjct: 2037 TPITTTTTVTPTPTPTGTQTPTTT 2060



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 134/634 (21%), Positives = 197/634 (31%), Gaps = 68/634 (10%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 2139 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2196

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 2197 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 2243

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 2244 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 2286

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 2287 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 2340

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
              +V+P   P    +    P      +   P+ +        P+   +     P   G Q
Sbjct: 2341 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2400

Query: 959  PPSKI-------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAG 1011
             P+         +  TP P  T +    P++  T   PT  P     P++T IT   +  
Sbjct: 2401 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2460

Query: 1012 GHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                P GT +P ++   T T+      PT +     T +  +      P  +  Q P   
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     +  P+P  P     P    IT   + +P PT +    Q     P    T  T T
Sbjct: 2521 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPT 2577

Query: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
              P  T  P   P   T T  PT P P+ T    T  +       P+P            
Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP-----PLPETW 1239
            I   +     +  P P   Q     P+   T   P     G  TP   P      +  T 
Sbjct: 2637 I---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2693

Query: 1240 TPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
            TPT   +P   P     T    P    ++ P+++
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2727



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 134/634 (21%), Positives = 197/634 (31%), Gaps = 68/634 (10%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 2392 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2449

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 2450 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 2496

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 2497 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 2539

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 2540 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 2593

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
              +V+P   P    +    P      +   P+ +        P+   +     P   G Q
Sbjct: 2594 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2653

Query: 959  PPSKI-------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAG 1011
             P+         +  TP P  T +    P++  T   PT  P     P++T IT   +  
Sbjct: 2654 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2713

Query: 1012 GHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                P GT +P ++   T T+      PT +     T +  +      P  +  Q P   
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2773

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     +  P+P  P     P    IT   + +P PT +    Q     P    T  T T
Sbjct: 2774 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPT 2830

Query: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
              P  T  P   P   T T  PT P P+ T    T  +       P+P            
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP-----PLPETW 1239
            I   +     +  P P   Q     P+   T   P     G  TP   P      +  T 
Sbjct: 2890 I---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2946

Query: 1240 TPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
            TPT   +P   P     T    P    ++ P+++
Sbjct: 2947 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2980



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 134/634 (21%), Positives = 197/634 (31%), Gaps = 68/634 (10%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 2645 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2702

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 2749

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 2750 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 2792

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 2793 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 2846

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
              +V+P   P    +    P      +   P+ +        P+   +     P   G Q
Sbjct: 2847 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2906

Query: 959  PPSKI-------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAG 1011
             P+         +  TP P  T +    P++  T   PT  P     P++T IT   +  
Sbjct: 2907 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2966

Query: 1012 GHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                P GT +P ++   T T+      PT +     T +  +      P  +  Q P   
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     +  P+P  P     P    IT   + +P PT +    Q     P    T  T T
Sbjct: 3027 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPT 3083

Query: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
              P  T  P   P   T T  PT P P+ T    T  +       P+P            
Sbjct: 3084 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP-----PLPETW 1239
            I   +     +  P P   Q     P+   T   P     G  TP   P      +  T 
Sbjct: 3143 I---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3199

Query: 1240 TPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
            TPT   +P   P     T    P    ++ P+++
Sbjct: 3200 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3233



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 134/634 (21%), Positives = 197/634 (31%), Gaps = 68/634 (10%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 2898 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 2956 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 3002

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 3003 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 3045

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 3046 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 3099

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
              +V+P   P    +    P      +   P+ +        P+   +     P   G Q
Sbjct: 3100 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3159

Query: 959  PPSKI-------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAG 1011
             P+         +  TP P  T +    P++  T   PT  P     P++T IT   +  
Sbjct: 3160 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3219

Query: 1012 GHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                P GT +P ++   T T+      PT +     T +  +      P  +  Q P   
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     +  P+P  P     P    IT   + +P PT +    Q     P    T  T T
Sbjct: 3280 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPT 3336

Query: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
              P  T  P   P   T T  PT P P+ T    T  +       P+P            
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP-----PLPETW 1239
            I   +     +  P P   Q     P+   T   P     G  TP   P      +  T 
Sbjct: 3396 I---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452

Query: 1240 TPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
            TPT   +P   P     T    P    ++ P+++
Sbjct: 3453 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 134/634 (21%), Positives = 197/634 (31%), Gaps = 68/634 (10%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 3151 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3208

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 3209 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 3255

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 3256 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 3298

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 3299 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 3352

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
              +V+P   P    +    P      +   P+ +        P+   +     P   G Q
Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3412

Query: 959  PPSKI-------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAG 1011
             P+         +  TP P  T +    P++  T   PT  P     P++T IT   +  
Sbjct: 3413 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3472

Query: 1012 GHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                P GT +P ++   T T+      PT +     T +  +      P  +  Q P   
Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3532

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     +  P+P  P     P    IT   + +P PT +    Q     P    T  T T
Sbjct: 3533 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPT 3589

Query: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
              P  T  P   P   T T  PT P P+ T    T  +       P+P            
Sbjct: 3590 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3648

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP-----PLPETW 1239
            I   +     +  P P   Q     P+   T   P     G  TP   P      +  T 
Sbjct: 3649 I---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3705

Query: 1240 TPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
            TPT   +P   P     T    P    ++ P+++
Sbjct: 3706 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3739



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 134/634 (21%), Positives = 197/634 (31%), Gaps = 68/634 (10%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 3404 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3461

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 3462 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 3508

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 3509 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 3551

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 3552 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 3605

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGGAGQPLPLVSPPFSVPVQNGAQ 958
              +V+P   P    +    P      +   P+ +        P+   +     P   G Q
Sbjct: 3606 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3665

Query: 959  PPSKI-------IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAG 1011
             P+         +  TP P  T +    P++  T   PT  P     P++T IT   +  
Sbjct: 3666 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3725

Query: 1012 GHALPLGT-SPASSQAGTVTSY----GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLA 1066
                P GT +P ++   T T+      PT +     T +  +      P  +  Q P   
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3785

Query: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126
            P     +  P+P  P     P    IT   + +P PT +    Q     P    T  T T
Sbjct: 3786 PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTG--TQTPTTTPITTTTTVTPT 3842

Query: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186
              P  T  P   P   T T  PT P P+ T    T  +       P+P            
Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3901

Query: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPT--APESELEGQPTPPAPP-----PLPETW 1239
            I   +     +  P P   Q     P+   T   P     G  TP   P      +  T 
Sbjct: 3902 I---TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3958

Query: 1240 TPTARSSPPLPPPAEERTSAKGPETMASKFPSSS 1273
            TPT   +P   P     T    P    ++ P+++
Sbjct: 3959 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3992



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 111/510 (21%), Positives = 163/510 (31%), Gaps = 79/510 (15%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 3956 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4013

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
             +P+  +   +   +   T             T    P T T  +  TP       P   
Sbjct: 4014 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTT- 4060

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVA 839
                  P   TT  +          P P G   P        IT    + PT        
Sbjct: 4061 -----TPITTTTTVTPT--------PTPTGTQTPTTTP----ITTTTTVTPTPTPTGTQT 4103

Query: 840  PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899
            P   P   T    P+ P PT +   T  P T+T         PTP     Q+  + P   
Sbjct: 4104 PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTPITT 4157

Query: 900  AQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQP 959
              +V+P   P    +    P      +  P+ +  G   G P    + P +    +   P
Sbjct: 4158 TTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTGPPTHTSTAPIAELTTSNPPP 4216

Query: 960  PSKIIQL---TPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALP 1016
             S   Q    T  P++  + L+  L PA     T+ P     P++T       +GGH L 
Sbjct: 4217 ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT-------SGGHTLS 4269

Query: 1017 LGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAP-------GQ 1069
               S  +S  GT     PT     G +S  P+ P+ VQ   ++   P   P         
Sbjct: 4270 PPPSTTTSPPGT-----PTRGTTTGSSS-APT-PSTVQTTTTSAWTPTPTPLSTPSIIRT 4322

Query: 1070 VGVSPVPSPQLPPACA------APGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVA 1123
             G+ P PS  L   C       APG  V    Y        +      S +     Y  +
Sbjct: 4323 TGLRPYPSSVLI-CCVLNDTYYAPGEEVYNGTYG------DTCYFVNCSLSCTLEFYNWS 4375

Query: 1124 TSTTPPAATILPKGPPAPATATPAPTSPFP 1153
              +TP       K  P P+  +  P+ P P
Sbjct: 4376 CPSTPSPTPTPSKSTPTPSKPSSTPSKPTP 4405



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 102/501 (20%), Positives = 133/501 (26%), Gaps = 106/501 (21%)

Query: 1126 TTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIA 1185
            TTP   T  P  PP   T  P  T+P P  T      +   P    PSP           
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTT-----TTTPPPTTTPSP----------- 1440

Query: 1186 SIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTP--TA 1243
                                      P+   T P       PT    PP+  T TP  T 
Sbjct: 1441 --------------------------PITTTTTPP------PTTTPSPPISTTTTPPPTT 1468

Query: 1244 RSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAP 1303
              SPP   P+   T+   P T  +  P +++              P T P   PA     
Sbjct: 1469 TPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP-----------SPPTTTPITPPASTTTL 1517

Query: 1304 GGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELP 1363
              ++  S       TP             + PP    T                      
Sbjct: 1518 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577

Query: 1364 EFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSE 1423
               P    PSP   +  T P     S        T   + P   T+P       S  ++ 
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPS------PPTTTTTTPPPTTTP-------SPPTTT 1624

Query: 1424 PNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGF 1483
            P TP ++       T   T T +               S   T      +          
Sbjct: 1625 PITPPTSTT-----TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTT 1679

Query: 1484 FPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGT 1543
             PS+  T           PS     +             T T  P     P P PP T T
Sbjct: 1680 TPSSPITTT---------PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP-PPTTMT 1729

Query: 1544 AAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP---PPESGP--------------GQP 1586
              +P  TPSP      T P + + +     PLPP   PP   P                 
Sbjct: 1730 TPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWT 1789

Query: 1587 GWEGAPQPSPPPPGPSTAATG 1607
            GW  + +P+   PG  T   G
Sbjct: 1790 GWLDSGKPNFHKPGGDTELIG 1810



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 80/360 (22%), Positives = 121/360 (33%), Gaps = 52/360 (14%)

Query: 663  PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP---NDTAGARTEMGTGSRVPG 719
            P   P  T  T    P+++T   +   P PT  +   +      T    T   TG++ P 
Sbjct: 4071 PTPTPTGTQ-TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4128

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTP---GYGAPAPP 776
             +P+  +   +   +   T             T    P T T  +  TP   G   P   
Sbjct: 4129 TTPITTTTTVTPTPTPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTTT 4176

Query: 777  AVQFIAQGAPGG---GTTAGSGAGAGSGP------NGPVPLGILQPGALGKAGGITQVQY 827
             +       P     GT  G      + P      + P P       +   +  +T+   
Sbjct: 4177 PITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTT 4236

Query: 828  ILPTLPQQLQVAPAPAPAPGTKAAAPSG-----PAPTTSIRFTLPPGTSTNGKVL-AATA 881
            +L TLP  +++     P+  T     SG     P P+T+   T PPGT T G    +++A
Sbjct: 4237 LLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT---TSPPGTPTRGTTTGSSSA 4293

Query: 882  PTPGIPILQSV----PSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGG 937
            PTP      +     P+  P    S+       P  S+ L+   +     AP   V  G 
Sbjct: 4294 PTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGT 4353

Query: 938  AGQPLPLVSPPFSVPVQ--NGAQP--------PSKIIQLTPVPVSTPSGLVPPLSPATLP 987
             G     V+   S  ++  N + P        PSK       P STPS   P   P   P
Sbjct: 4354 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 4413



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 50/200 (25%), Positives = 65/200 (32%), Gaps = 40/200 (20%)

Query: 1427 PKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPS 1486
            P S   +GD  TFD      ED+  E    K P+ SL +                G    
Sbjct: 1314 PSSGSDDGDRETFDGVCGAPEDI--ECRSVKDPHLSLEQL---------------GQKVQ 1356

Query: 1487 AQATAAFQARYADIF---PSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGT 1543
               +  F  +  D F   P  +C   KIR      M     T  PP      P PPPT T
Sbjct: 1357 CDVSVGFICKNEDQFGNGPFGLCYDYKIRVNCCWPMDKCITTPSPP---TTTPSPPPTST 1413

Query: 1544 AAAP-----------------APTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQP 1586
               P                   TPSP      T P + + +   +    PPP + P  P
Sbjct: 1414 TTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPP 1473

Query: 1587 GWEGAPQPSPPPPGPSTAAT 1606
                +P  + P P  +T  T
Sbjct: 1474 TTTPSPPTTTPSPPTTTTTT 1493



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 31/90 (34%), Positives = 37/90 (41%), Gaps = 7/90 (7%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++G
Sbjct: 4139 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTG 4196

Query: 1583 PGQPGWEGAP----QPSPPPPGPSTAATGR 1608
            P       AP      S PPP  ST  T R
Sbjct: 4197 P-PTHTSTAPIAELTTSNPPPESSTPQTSR 4225



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 1931 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 1988

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 1989 TTTPITTTTTVTPTPTPTGTQTPTT 2013



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 1954 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2011

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2012 TTTPITTTTTVTPTPTPTGTQTPTT 2036



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 1977 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2034

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2035 TTTPITTTTTVTPTPTPTGTQTPTT 2059



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2000 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2057

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2058 TTTPITTTTTVTPTPTPTGTQTPTT 2082



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2023 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2080

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2081 TTTPITTTTTVTPTPTPTGTQTPTT 2105



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2046 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2103

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2104 TTTPITTTTTVTPTPTPTGTQTPTT 2128



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2069 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2126

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2127 TTTPITTTTTVTPTPTPTGTQTPTT 2151



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2092 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2149

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2150 TTTPITTTTTVTPTPTPTGTQTPTT 2174



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2115 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2172

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2173 TTTPITTTTTVTPTPTPTGTQTPTT 2197



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2138 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2195

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2196 TTTPITTTTTVTPTPTPTGTQTPTT 2220



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2161 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2218

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2219 TTTPITTTTTVTPTPTPTGTQTPTT 2243



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2184 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2241

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTT 2266



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2207 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2264

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTT 2289



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2230 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2287

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2288 TTTPITTTTTVTPTPTPTGTQTPTT 2312



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2253 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2310

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2311 TTTPITTTTTVTPTPTPTGTQTPTT 2335



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2276 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2333

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2334 TTTPITTTTTVTPTPTPTGTQTPTT 2358



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2299 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2356

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2357 TTTPITTTTTVTPTPTPTGTQTPTT 2381



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2379

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2380 TTTPITTTTTVTPTPTPTGTQTPTT 2404



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2345 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2402

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTT 2427



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2368 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2425

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTPTT 2450



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2391 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2448

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2449 TTTPITTTTTVTPTPTPTGTQTPTT 2473



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2414 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2471

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2472 TTTPITTTTTVTPTPTPTGTQTPTT 2496



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2437 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2494

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2495 TTTPITTTTTVTPTPTPTGTQTPTT 2519



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2460 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2517

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2518 TTTPITTTTTVTPTPTPTGTQTPTT 2542



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2540

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2541 TTTPITTTTTVTPTPTPTGTQTPTT 2565



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2506 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2563

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2564 TTTPITTTTTVTPTPTPTGTQTPTT 2588



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2529 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2586

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTT 2611



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2609

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2610 TTTPITTTTTVTPTPTPTGTQTPTT 2634



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2575 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2632

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQTPTT 2657



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2598 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2655

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTT 2680



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2621 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2678

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTPTT 2703



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2644 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2701

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2702 TTTPITTTTTVTPTPTPTGTQTPTT 2726



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2724

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2725 TTTPITTTTTVTPTPTPTGTQTPTT 2749



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTT 2772



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2713 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2770

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2771 TTTPITTTTTVTPTPTPTGTQTPTT 2795



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2793

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2794 TTTPITTTTTVTPTPTPTGTQTPTT 2818



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2759 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2816

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTT 2841



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2782 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2839

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2840 TTTPITTTTTVTPTPTPTGTQTPTT 2864



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2862

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2863 TTTPITTTTTVTPTPTPTGTQTPTT 2887



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2828 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2885

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTT 2910



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2851 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2908

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTPTT 2933



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2931

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2932 TTTPITTTTTVTPTPTPTGTQTPTT 2956



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 2954

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTT 2979



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 2920 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 2978 TTTPITTTTTVTPTPTPTGTQTPTT 3002



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2943 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3000

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTPTT 3025



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3023

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTT 3048



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 2989 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3046

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3047 TTTPITTTTTVTPTPTPTGTQTPTT 3071



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3012 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3069

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTT 3094



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3035 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3092

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3093 TTTPITTTTTVTPTPTPTGTQTPTT 3117



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3058 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3115

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3116 TTTPITTTTTVTPTPTPTGTQTPTT 3140



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3081 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3138

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTT 3163



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3161

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3162 TTTPITTTTTVTPTPTPTGTQTPTT 3186



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3184

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTPTT 3209



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3150 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3207

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3208 TTTPITTTTTVTPTPTPTGTQTPTT 3232



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3230

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTT 3255



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3253

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3254 TTTPITTTTTVTPTPTPTGTQTPTT 3278



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3219 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3276

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQTPTT 3301



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTT 3324



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3265 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3322

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3323 TTTPITTTTTVTPTPTPTGTQTPTT 3347



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3345

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3346 TTTPITTTTTVTPTPTPTGTQTPTT 3370



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3368

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTT 3393



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3334 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3391

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTT 3416



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3414

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3415 TTTPITTTTTVTPTPTPTGTQTPTT 3439



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3380 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3437

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3438 TTTPITTTTTVTPTPTPTGTQTPTT 3462



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3403 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3460

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3461 TTTPITTTTTVTPTPTPTGTQTPTT 3485



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3426 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3483

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3484 TTTPITTTTTVTPTPTPTGTQTPTT 3508



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3506

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQTPTT 3531



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3472 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3529

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3530 TTTPITTTTTVTPTPTPTGTQTPTT 3554



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3495 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3552

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTT 3577



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3575

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTPTT 3600



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3541 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3598

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3599 TTTPITTTTTVTPTPTPTGTQTPTT 3623



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3564 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3621

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3622 TTTPITTTTTVTPTPTPTGTQTPTT 3646



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3644

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTPTT 3669



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3667

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3668 TTTPITTTTTVTPTPTPTGTQTPTT 3692



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3633 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3690

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3691 TTTPITTTTTVTPTPTPTGTQTPTT 3715



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3656 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3713

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTT 3738



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3679 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3736

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3737 TTTPITTTTTVTPTPTPTGTQTPTT 3761



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3702 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3759

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3760 TTTPITTTTTVTPTPTPTGTQTPTT 3784



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3725 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3782

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTT 3807



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3748 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3805

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTPTT 3830



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3828

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3829 TTTPITTTTTVTPTPTPTGTQTPTT 3853



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3794 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3851

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTT 3876



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3817 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3874

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTT 3899



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3840 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3897

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3898 TTTPITTTTTVTPTPTPTGTQTPTT 3922



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3863 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3920

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTT 3945



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3886 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3943

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTPTT 3968



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3909 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 3966

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTPTT 3991



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3932 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3989

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 3990 TTTPITTTTTVTPTPTPTGTQTPTT 4014



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 3955 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 4012

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 4013 TTTPITTTTTVTPTPTPTGTQTPTT 4037



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 3978 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4035

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 4036 TTTPITTTTTVTPTPTPTGTQTPTT 4060



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 4001 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 4058

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 4059 TTTPITTTTTVTPTPTPTGTQTPTT 4083



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 4024 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4081

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 4082 TTTPITTTTTVTPTPTPTGTQTPTT 4106



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 4047 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 4104

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTT 4129



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T     PTP+P G   PT+    + T     P P   ++ 
Sbjct: 4070 TPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4127

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 4128 TTTPITTTTTVTPTPTPTGTQTPTT 4152



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG 1582
            TPT  P G + P   P  T T   P PTP+  G   PT+    + T     P P   ++ 
Sbjct: 4093 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPTTTPITTTTTVTPTPTPTGTQTP 4150

Query: 1583 PGQP-GWEGAPQPSPPPPGPSTAAT 1606
               P        P+P P G  T  T
Sbjct: 4151 TTTPITTTTTVTPTPTPTGTQTPTT 4175



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 30/86 (34%), Positives = 35/86 (40%), Gaps = 14/86 (16%)

Query: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAA--PPLPPPPE 1580
            TPT  P G + P   P  T T   P  TP+P G    T P + + TA  A      PPPE
Sbjct: 4162 TPTPTPTGTQTPTTTPITTTTTVTP--TPTPTG--TQTGPPTHTSTAPIAELTTSNPPPE 4217

Query: 1581 SGPGQPGWEGAPQPSPPPPGPSTAAT 1606
            S          PQ S     P T +T
Sbjct: 4218 S--------STPQTSRSTSSPLTEST 4235



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 26/132 (19%), Positives = 44/132 (33%), Gaps = 11/132 (8%)

Query: 42   PFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSA------DPE 95
            P    +   P+  P+  Q P + P+ +  +  P  +       PP  T +A         
Sbjct: 4154 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSN 4213

Query: 96   RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSI 155
             PP ++ P++                  PP  E  ++ PP  P   + T   H     ++
Sbjct: 4214 PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGH-----TL 4268

Query: 156  MSPEIQLPLPPG 167
              P      PPG
Sbjct: 4269 SPPPSTTTSPPG 4280


>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
           sapiens]
          Length = 941

 Score =  110 bits (275), Expect = 1e-23
 Identities = 56/117 (47%), Positives = 71/117 (60%), Gaps = 7/117 (5%)

Query: 170 RTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRT 229
           + Q L A   E+D    +D  SP +R     RRPMNAF++F KRHR+LV Q HP  DNR 
Sbjct: 54  KVQLLGADGLEQDVGETEDDESPEQRA----RRPMNAFLLFCKRHRSLVRQEHPRLDNRG 109

Query: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWC---NKDRKKSSSEAKP 283
            +KIL +WW  L PKEKQKY D+A + K+A  KA+P +KWC   NK  K  +    P
Sbjct: 110 ATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNP 166


>gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo
           sapiens]
          Length = 911

 Score =  110 bits (275), Expect = 1e-23
 Identities = 56/117 (47%), Positives = 71/117 (60%), Gaps = 7/117 (5%)

Query: 170 RTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRT 229
           + Q L A   E+D    +D  SP +R     RRPMNAF++F KRHR+LV Q HP  DNR 
Sbjct: 54  KVQLLGADGLEQDVGETEDDESPEQRA----RRPMNAFLLFCKRHRSLVRQEHPRLDNRG 109

Query: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWC---NKDRKKSSSEAKP 283
            +KIL +WW  L PKEKQKY D+A + K+A  KA+P +KWC   NK  K  +    P
Sbjct: 110 ATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNP 166


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score =  109 bits (273), Expect = 2e-23
 Identities = 277/1178 (23%), Positives = 384/1178 (32%), Gaps = 216/1178 (18%)

Query: 507  RPPLDPEPPGPP-----DPPVAFGKGYGSA----PSSSASSPASSSASAATSFSLGSGTF 557
            +PP  P PPG        P    G+ YG      P  +A S    +AS + S+S G    
Sbjct: 481  QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA 540

Query: 558  KAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP--- 614
                SG G   GP      G GG A+PS   R L   PAT    RP  VG    PG    
Sbjct: 541  L---SGHGGGWGP---SSLGGGGEASPSHIIRPLQSPPAT---GRPPGVGSPGAPGKYLS 591

Query: 615  SVIA-----APPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAA 669
            SV+A     APP  G     +        + +G G+ + + P      G P A  +    
Sbjct: 592  SVLASAPFLAPPGAG-----SYAAGAGGYKGKGDGSELLAGP------GGPPAERTEDEE 640

Query: 670  TMVTNVVRPVSSTPVPIASKPFPTSGRAEASPN--DTAGARTEMGTGSRVPGGSPLGVSL 727
             ++ ++++  S      A       G A+AS     + GA    GT   +    P    L
Sbjct: 641  FLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHL 700

Query: 728  VYSDKKSAAATSPAPHLVAGPL--LGTVGKAPA----TVTNLLVGTPGYGAPAPPAVQFI 781
                + SA+    A   +   L  L    K P     T   L      YGA A     F+
Sbjct: 701  QSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFL 760

Query: 782  AQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPT-----LPQQL 836
             +  P    TA S          P P G+L      +AGG   +  +LP      LP  L
Sbjct: 761  QKSPPPPPPTAQS--------TQPTPHGLLL-----EAGG-PDLPLVLPPPPPQLLPSVL 806

Query: 837  QVAPAPAPA----------PGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGI 886
              AP+P+P+          P T+  AP  P P        PP        L A   + G+
Sbjct: 807  SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP-------PPPPPPMPLQLEAHLRSHGL 859

Query: 887  PILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVS 946
                  P+AP P+ +    +   PPG   +LL                  GA +PLP   
Sbjct: 860  E-----PAAPSPRLRPEESLD--PPGAMQELL------------------GALEPLPPAP 894

Query: 947  PPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQ-KVLLPSSTRIT 1005
                V   N           +P P  T +    PL+    P    Q + +   P+   + 
Sbjct: 895  GDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMF 954

Query: 1006 YVQSAGGHALPLGTS-PASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPL 1064
                 GG A   G + P   +       GP      G  +  P GP    P  ++G  P 
Sbjct: 955  ----GGGAADDYGKAGPPEDEGDPKAGAGPPP----GPPAYDPYGPYC--PGRASGAGPE 1004

Query: 1065 LAPGQVGVSPVPSPQLPPAC-AAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVA 1123
              PG +G+ P   P+LP    A P G + +  +  +P P        P   PP       
Sbjct: 1005 -TPG-LGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPP--------PPPPPP------- 1047

Query: 1124 TSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAA 1183
                PPA    PKG       +P   S  P     + ++ L+  + + P  + P+K+ A 
Sbjct: 1048 ----PPAPASEPKG----GLTSPIFCSTKPKKLLKTSSFHLL--RRRDPPFQTPKKLYAQ 1097

Query: 1184 IASIPVGSFEAGASGRPGPAPRQ------PLEPGPVREPTAPESELEGQPTPPAPPPLPE 1237
                     +A         PR+           P   P          P P  P     
Sbjct: 1098 EYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGR 1157

Query: 1238 TWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDW----RVPGQGLENRGEP---- 1289
              T   R  PP P         + P T      S+ +D     R  G+G   + E     
Sbjct: 1158 KPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGT 1217

Query: 1290 ---PTPPSPAPAPAVAPGGSSESSSGRAAGDTPE--------RKEAAGTGKKVKVRPPPL 1338
               P  P          G    +SSG A   T          R++     K+V+ + P +
Sbjct: 1218 RLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEM 1277

Query: 1339 KKTFDSVDNRVLSEVDFEERFAELPEFR----------PEEVLPSPTLQSLATSPRAILG 1388
            K  F      + S +DF +     P             P+ V PS   + L   P A   
Sbjct: 1278 KSGF------MASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPA 1331

Query: 1389 SYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAED 1448
                    +  L  A E   S    +   S C       K      ++ T     ++ ED
Sbjct: 1332 VPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKR-----NLETLPSFSSDEED 1386

Query: 1449 VLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQ 1508
             + +    +   SS    LD       +        P A A A          PS     
Sbjct: 1387 SVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSA---- 1442

Query: 1509 LKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPA-PTPSPAGGPDPTSPSSDSG 1567
                   +  +    P   PP A  P P PPP      PA P+P P   P P+SP     
Sbjct: 1443 -NSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPP--- 1498

Query: 1568 TAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAA 1605
                 PPLPPPP              PSPPPP P  AA
Sbjct: 1499 -----PPLPPPPPPA----------MPSPPPPPPPAAA 1521



 Score = 88.6 bits (218), Expect = 4e-17
 Identities = 284/1222 (23%), Positives = 383/1222 (31%), Gaps = 346/1222 (28%)

Query: 304  GTAAAPG--VSSELLSVAAQTLLSSDTKAPGSSSC-----GAERLHTVGGPGSARPRAFS 356
            G+  APG  +SS L S        + + A G+        G+E L   GGP + R     
Sbjct: 581  GSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERT---- 636

Query: 357  HSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRP 416
                      E +   +Q L Q  S P +        + GA    A+ G GG+  A G P
Sbjct: 637  ----------EDEEFLIQHLLQAPSPPRTSGADGLVGEDGAAD--ASKGLGGSGGAGG-P 683

Query: 417  PLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDL---KCKERVTD 473
            P  P         A ED      + VI           D+G  T  ++L   + KE+   
Sbjct: 684  PGTP------YELAKEDPQRYHLQSVIRTSAS-----LDEG-ATAALELGLGRLKEKKKG 731

Query: 474  SESGDSSGEDPEG------NKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKG 527
             E G   GE PEG      + G G K     ++ S              PP PP      
Sbjct: 732  PERG---GETPEGLATSVVHYGAGAKELGAFLQKS--------------PPPPP------ 768

Query: 528  YGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPG--------AG 579
                P++ ++ P                     E+G       L PPPP         A 
Sbjct: 769  ----PTAQSTQPTPHGLLL--------------EAGGPDLPLVLPPPPPQLLPSVLSHAP 810

Query: 580  GPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEE 639
             P+  +       ++PAT         G  +PP P     PP           +P   E 
Sbjct: 811  SPSPSASKVGVHLLEPAT-------RDGAPQPPPPPPPPPPP-----------MPLQLEA 852

Query: 640  QEGGGARVPSAPAPSLAYGAPAAPLSRPAATM-VTNVVRPVSSTPVPIASKPFPTSGRAE 698
                    P+AP+P L    P   L  P A   +   + P+   P      P  + G+  
Sbjct: 853  HLRSHGLEPAAPSPRLR---PEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGK-- 907

Query: 699  ASPNDTAGA-RTEMGTGSRVPGGSPLGV-----SLVYSDKKSAAATSPAPHLVAGPLLGT 752
                D AGA R+    G++ P   PL       SL+  +++S   T     +  G     
Sbjct: 908  ----DPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTME--EMFGGGAADD 961

Query: 753  VGKAPATVTNLLVGTPGYGA---PAPPAVQFIAQGAPGGGTTAGSGA-GAGSGPNGPV-- 806
             GKA         G P  GA   P PPA        PG  + AG    G G  PN P   
Sbjct: 962  YGKAGPPEDE---GDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPEL 1018

Query: 807  -------PLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPT 859
                   PLG++Q G                  P Q    P P P P      P  PA  
Sbjct: 1019 PSTVNAEPLGLIQSG------------------PHQAAPPPPPPPPP------PPAPASE 1054

Query: 860  TSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLP 919
                 T P   ST  K L  T+      + +  P    PK       +       A +  
Sbjct: 1055 PKGGLTSPIFCSTKPKKLLKTSSFH--LLRRRDPPFQTPKKLYAQEYEFEADEDKADVPA 1112

Query: 920  GKVLVPLAAPSM--SVRGGGAGQPLPLV-----SPPFSVPVQNGAQP----------PSK 962
               L P   P +  S R   A  PL  +     +P    P + G +P          P  
Sbjct: 1113 DIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRG 1172

Query: 963  IIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALP------ 1016
              ++ P+ V T +G      PA+   PT   +K       R    + AGG  L       
Sbjct: 1173 RPRIRPLEVPTTAG------PASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLK 1226

Query: 1017 -----------LGTSPASSQAGT--------------------VTSYGPT--SSVALGFT 1043
                       LGTS   + +GT                    V    P   S     F 
Sbjct: 1227 IKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFL 1286

Query: 1044 SLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPS----PQLPPACAAPGGPVITAFYSGS 1099
                SG     PL  AG  P L+P +     VP+    PQ P   A P  P   AF  G 
Sbjct: 1287 DFLKSGKRH-PPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGG 1345

Query: 1100 --------------PAPTSSAP--------------------LAQPSQAPPSLVYTVATS 1125
                          P+P                         +A+      S+   ++  
Sbjct: 1346 ALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISAL 1405

Query: 1126 TTPPAA----TILPKGPP-APATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKV 1180
              PP A    T  P GPP APA A P P  P P   + +   +   P  +   P  P   
Sbjct: 1406 DDPPLAGPKDTSTPDGPPLAPAAAVPGPP-PLPGLPSANSNGTPEPPLLEEKPPPTPP-- 1462

Query: 1181 KAAIASIPVGSFEAGASGRPGPAPR-QPLEPGPVREPTAPESELEGQPTP--PAPPPLPE 1237
                               P P P+ QP  P P  +P  P       PTP  P PPPLP 
Sbjct: 1463 -------------------PAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP 1503

Query: 1238 TWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAP 1297
               P A  SPP PPP      A  PE  A+  P                 E P  P   P
Sbjct: 1504 P-PPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP-----------------EDPELPDTRP 1545

Query: 1298 ------APAVAPGGSSESSSGRAAG---------------DTPERKEAAGTGKKVKVRPP 1336
                      A  G ++  +G + G               D P  K A  TG++    PP
Sbjct: 1546 LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGRE----PP 1601

Query: 1337 PLKKTFDSVDNRVLSEVDFEER 1358
            P+ +   ++  +   E+   +R
Sbjct: 1602 PIWRVQKALLQKFTPEIKDGQR 1623



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 276/1219 (22%), Positives = 395/1219 (32%), Gaps = 248/1219 (20%)

Query: 508  PPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSAS--------AATSFSLGSGTFKA 559
            PP  P PP PP PP      +    SSSA++ A+  +S        AA            
Sbjct: 225  PPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPR 284

Query: 560  QES-----GQGSTAGPLRPPPP----------------------------GAGGPA---- 582
            Q++      + ++A P  PPPP                            G G P+    
Sbjct: 285  QDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAG 344

Query: 583  TPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEG 642
             PSKA        A+ R   PE+ GG              GGG   + ++  P  +  +G
Sbjct: 345  EPSKAGPSGATAGASGRATGPEAAGG----------GGAGGGGGGYRPIIQSPGYKTGKG 394

Query: 643  GGARVPSAPAPSLAYGAPAAPLSRP------AATMVTNVVRPVSSTPVPIASKPFPTSGR 696
            G             YGA A   +RP      A     ++  P ++     AS      G+
Sbjct: 395  G-------------YGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQ 441

Query: 697  AEASPNDTAGARTEMGTGSRVPGGSPLGVSLV--YSDKKSAAATSPAPHLVAGPLLGTV- 753
            A  SP    G       G    GG    +S    YS       + P P     P L T  
Sbjct: 442  A-YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPP-----PGLATCQ 495

Query: 754  GKAPATVTNLLVGTPGYGAPAPPA-VQFIAQGAPG-----GGTTAGSGAGAGSGPNGPVP 807
              +P  +   L G  G   P P A  Q +   +P      G + A SG G G GP+    
Sbjct: 496  SYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPS---- 551

Query: 808  LGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSG---PAPTTSIRF 864
                   +LG  G  +    I P     LQ  PA    PG  +    G    +   S  F
Sbjct: 552  -------SLGGGGEASPSHIIRP-----LQSPPATGRPPGVGSPGAPGKYLSSVLASAPF 599

Query: 865  TLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK--------AQSVSPVQAPPPGGSAQ 916
              PPG  +                L + P  PP +         Q +    +PP    A 
Sbjct: 600  LAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGAD 659

Query: 917  LLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSG 976
             L G+     A+  +   GG  G P      P+ +  ++  +   + +  T   +   + 
Sbjct: 660  GLVGEDGAADASKGLGGSGGAGGPP----GTPYELAKEDPQRYHLQSVIRTSASLDEGAT 715

Query: 977  LVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGT--------SPASSQAGT 1028
                L    L      P++         T V   G  A  LG          P ++Q+  
Sbjct: 716  AALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQ 775

Query: 1029 VTSYG---PTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGV--------SPVPS 1077
             T +G         L    L P  P  +  +LS   +P  +  +VGV           P 
Sbjct: 776  PTPHGLLLEAGGPDLPLV-LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQ 834

Query: 1078 PQLPPACAAPGGPVITAFY--SGSPAPTSSAPLAQPSQA--PPSLVYTV--ATSTTPPAA 1131
            P  PP    P  P+    +  S    P + +P  +P ++  PP  +  +  A    PPA 
Sbjct: 835  PPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAP 894

Query: 1132 TILPKGPPAPATATPAPT--SPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPV 1189
                 GPP      PA    SP P  T       L +     P      + ++   ++  
Sbjct: 895  GDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTS--ICFPDSLLQDEERSFFPTME- 951

Query: 1190 GSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPL 1249
              F  GA+   G A       GP  +   P++   G   PP PP           +  P 
Sbjct: 952  EMFGGGAADDYGKA-------GPPEDEGDPKA---GAGPPPGPP-----------AYDPY 990

Query: 1250 PPPAEERTSAKGPETMA-----SKFPSSSSDWRVPGQGLENRG------EPPTPPSPAPA 1298
             P    R S  GPET       +K P   S       GL   G       PP PP P PA
Sbjct: 991  GPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPA 1050

Query: 1299 PAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFE-- 1356
            PA  P G    +S       P++     +   ++ R PP    F +       E +FE  
Sbjct: 1051 PASEPKGG--LTSPIFCSTKPKKLLKTSSFHLLRRRDPP----FQTPKKLYAQEYEFEAD 1104

Query: 1357 ERFAELP---EFRPEEV--LPSPTLQSLATSPRAIL-------GSYRKKRKNSTDLDSAP 1404
            E  A++P      P  +  L S      A SP   +       G    +R+      +  
Sbjct: 1105 EDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKR 1164

Query: 1405 EDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDR-----TGTEAEDVLG-ELEYDKV 1458
            + P  P+ + R R         P SA    D     R      G +AE+  G  LE    
Sbjct: 1165 DGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLE---- 1220

Query: 1459 PYSSLRRTLDQRRALVMQLFQDHGF-FPSAQATAAFQARYADIFPSKVCLQLKIREVRQK 1517
            P   L+  L   +A         G    S  A +       D   ++  ++ KI+EV +K
Sbjct: 1221 PLKPLKIKLSVPKA-------GEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEK 1273

Query: 1518 IMQ------------AATPTEQPPGAEAPL--PVPPPTGTAAAPAPTPSPAGGPDPTSPS 1563
              +              +    PP  +A L  P+ PP        P   PA G  P  P 
Sbjct: 1274 QPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKS-----VPPSVPARGLQPQPP- 1327

Query: 1564 SDSGTAQAAPPLPPPPESG 1582
                   A P +P PP SG
Sbjct: 1328 -------ATPAVPHPPPSG 1339



 Score = 84.7 bits (208), Expect = 6e-16
 Identities = 238/980 (24%), Positives = 315/980 (32%), Gaps = 210/980 (21%)

Query: 505  HCRPPLDPEPPGPPDPPVAF------GKGY---------------GSAPSSSASSPASSS 543
            H + P   +PP PP P  A       G  Y               G  PS  A  P+ + 
Sbjct: 291  HYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAG 350

Query: 544  ASAATSFSLG--SGTFKAQESGQGSTAGPLRP--PPPG-----AGGPATPSKATRFLPMD 594
             S AT+ + G  +G   A   G G   G  RP    PG      G  A    ATR  P  
Sbjct: 351  PSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATR--PPP 408

Query: 595  PATFRRKRPESVGGLEPPGPSVIAAPPSGGGNI---------LQTLVLPPNKEEQEGGGA 645
            P +    + +S+GG   P  +      SG G            Q L+ P    +  GGG 
Sbjct: 409  PRSTATPKCQSLGG---PAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQ 465

Query: 646  RVPSAPAPSLAYGAPAAPLSRPA---ATMVTNVVRPVSSTPVPIASKPFP-----TSGRA 697
                + APS + G P  P   P    AT  +     +      +  +P+P     + G  
Sbjct: 466  AQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLP 525

Query: 698  EASPN---DTAGARTEMGTG-----SRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPL 749
             ASP+    T  +    G G     S + GG     S +    +S  AT   P  V  P 
Sbjct: 526  TASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPG-VGSP- 583

Query: 750  LGTVGK------------APATVTNLLVGTPGY-----------GAPAPPA--------- 777
             G  GK            AP    +   G  GY           G   PPA         
Sbjct: 584  -GAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFL 642

Query: 778  VQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTL-PQ-- 834
            +Q + Q AP    T+G+    G         G+   G  G AGG     Y L    PQ  
Sbjct: 643  IQHLLQ-APSPPRTSGADGLVGEDGAADASKGL---GGSGGAGGPPGTPYELAKEDPQRY 698

Query: 835  --QLQVAPAPAPAPGTKAAAPSGPAPTTSIRF------TLPPGTSTNGKVLAATAPTPGI 886
              Q  +  + +   G  AA   G       +         P G +T+     A A   G 
Sbjct: 699  HLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGA 758

Query: 887  PILQSVPSAPPPKAQSVSP----------------VQAPPPGGSAQLLPGKVL-VPLAAP 929
              LQ  P  PPP AQS  P                V  PPP    QLLP  +   P  +P
Sbjct: 759  -FLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPP---PQLLPSVLSHAPSPSP 814

Query: 930  SMS----------VRGGGAGQPLPLVSPPFSVPVQ-------NGAQPPSKIIQLTPVPVS 972
            S S           R G    P P   PP  +P+Q       +G +P +   +L P    
Sbjct: 815  SASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESL 874

Query: 973  TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGT-VTS 1031
             P G +  L  A  P P +       P  T +    S G    P G   + S  GT    
Sbjct: 875  DPPGAMQELLGALEPLPPA-------PGDTGVGPPNSEGKD--PAGAYRSPSPQGTKAPR 925

Query: 1032 YGPTSSVALGFTSLGPSGPAF---VQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAA-- 1086
            + P +S+    + L     +F   ++ +   G A        G +  P  +  P   A  
Sbjct: 926  FVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAAD-----DYGKAGPPEDEGDPKAGAGP 980

Query: 1087 -PGGPVITAFYSGSPAPTSSAPLAQPS-----QAPPSLVYTVATSTTPPAATILPKGPPA 1140
             PG P    +    P   S A    P        PP L  TV      P   I  +  P 
Sbjct: 981  PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTV---NAEPLGLI--QSGPH 1035

Query: 1141 PATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRP 1200
             A   P P  P P A A      L +P      PK   K           SF      R 
Sbjct: 1036 QAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTS---------SFHL--LRRR 1084

Query: 1201 GPAPRQPLEPGPVREPTAPESELEGQPTP---PA-----PPPLPETWTPTARSSPPLPPP 1252
             P  + P      ++  A E E E        PA     P  LP+    + RS P L P 
Sbjct: 1085 DPPFQTP------KKLYAQEYEFEADEDKADVPADIRLNPRRLPDL-VSSCRSRPALSPL 1137

Query: 1253 AE-----ERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSS 1307
             +           GP     K   +  D     +G         P +  PA A  P   +
Sbjct: 1138 GDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGA 1197

Query: 1308 ESSSGRAAGDTPERKEAAGT 1327
            +   GR  G   + +EA GT
Sbjct: 1198 KKPRGRGRGRGRKAEEAGGT 1217



 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 180/810 (22%), Positives = 255/810 (31%), Gaps = 147/810 (18%)

Query: 877  LAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVP----LAAPSMS 932
            L +  P PG      +     P  Q+      P     +  LPG    P    L+A    
Sbjct: 95   LESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHP 154

Query: 933  VRGGGAGQPLP----LVSPPFSVPVQNGAQPPSKIIQLTPVPVST--------------- 973
               G    P+P    L  PPFS P  NG   P  ++ L P    T               
Sbjct: 155  ASFGSRPFPVPSSLSLQDPPFSPPA-NGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGV 213

Query: 974  --PSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTS 1031
              P+GL P  +P   PGP   P     P      +   A   A       +S Q    + 
Sbjct: 214  LGPAGLGPAQTPPYRPGPPDPPPP---PRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSG 270

Query: 1032 YGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACA-----A 1086
              P           GP  P    P     Q  ++   Q   S  P P  PPA A     +
Sbjct: 271  AAP-----------GPPPPERALP----RQDTVIKHYQRPASAQPPPPPPPAHALQHYLS 315

Query: 1087 PGGP----------VITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVAT--STTPPAATIL 1134
             GG             +    G P+P +     +PS+A PS     A+  +T P AA   
Sbjct: 316  CGGSYPSMGHRANLACSPLGGGEPSPGA----GEPSKAGPSGATAGASGRATGPEAA--- 368

Query: 1135 PKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQR-PSPKAPQKVKAAIASIPVGSFE 1193
              G          P    P    G   Y   A  A R P P++    K      P  ++ 
Sbjct: 369  GGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYA 428

Query: 1194 AGASGRPGPAPRQPLEPGPVREPTAPESELE----GQPTPPAPPPLPETWTPTARSSPPL 1249
             G +   G A  Q   PG  +    P++  +    GQ    +  P      P   S P  
Sbjct: 429  TGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGP-- 486

Query: 1250 PPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPS------PAPAPAVAP 1303
            PPP      +  P+ +  +      +   PG    ++G P   PS       +PA +   
Sbjct: 487  PPPGLATCQSYSPDQLQGQLYGVQGE-PYPGPAAHSQGLPTASPSLSYSTGHSPALSGHG 545

Query: 1304 GGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELP 1363
            GG   SS G     +P              RPP +         + LS V      A  P
Sbjct: 546  GGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGS--PGAPGKYLSSV-----LASAP 598

Query: 1364 EFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRR--RSSCS 1421
               P            A S  A  G Y+ K   S +L + P  P + + +          
Sbjct: 599  FLAPPG----------AGSYAAGAGGYKGKGDGS-ELLAGPGGPPAERTEDEEFLIQHLL 647

Query: 1422 SEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDH 1481
              P+ P+++  +G +   D     ++ + G       P +      +  +   +Q     
Sbjct: 648  QAPSPPRTSGADG-LVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRT 706

Query: 1482 GFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAE--------- 1532
                   ATAA              L+L +  +++K        E P G           
Sbjct: 707  SASLDEGATAA--------------LELGLGRLKEKKKGPERGGETPEGLATSVVHYGAG 752

Query: 1533 -----APLPVPPPTGTAAAPAPTPSP------AGGPD-----PTSPSSDSGTAQAAPPLP 1576
                 A L   PP     A +  P+P      AGGPD     P  P     +  +  P P
Sbjct: 753  AKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSP 812

Query: 1577 PPPESGPG----QPGW-EGAPQPSPPPPGP 1601
             P  S  G    +P   +GAPQP PPPP P
Sbjct: 813  SPSASKVGVHLLEPATRDGAPQPPPPPPPP 842



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 323/1462 (22%), Positives = 444/1462 (30%), Gaps = 344/1462 (23%)

Query: 328  TKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYS 387
            T+ P   S    +  ++GGP +A       +G  S  GG              +G  +YS
Sbjct: 404  TRPPPPRSTATPKCQSLGGPAAAYA-----TGKASGAGG--------------AGGQAYS 444

Query: 388  GPKPSTQYGAPGPFA-APGEGGALAA--------TGRPPLLPTRASRSQRAASEDMTSDE 438
              +P    G  GP A   G GG  A         +G PP  P+       A  +  + D+
Sbjct: 445  PGQPQ---GLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQ 501

Query: 439  ERMVICEEEGDD---DVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVF 495
             +  +   +G+          G  T    L      + + SG   G  P    G G    
Sbjct: 502  LQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASP 561

Query: 496  SPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSG 555
            S +IR   +   PP    PPG   P        G   SS  +S    +   A S++ G+G
Sbjct: 562  SHIIRPLQS---PPATGRPPGVGSPGAP-----GKYLSSVLASAPFLAPPGAGSYAAGAG 613

Query: 556  TFKAQESGQGSTAGPLRPPPP-------------GAGGPATPSKATRFLPMDPATFRRKR 602
             +K +  G    AGP  PP                A  P   S A   +  D A    K 
Sbjct: 614  GYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKG 673

Query: 603  PESVGGL-EPPG---------------PSVI--AAPPSGGGNILQTLVLPPNKEEQEG-- 642
                GG   PPG                SVI  +A    G      L L   KE+++G  
Sbjct: 674  LGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPE 733

Query: 643  GGARVPSAPAPSLA-YGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP 701
             G   P   A S+  YGA A  L              +  +P P    P PT+   + +P
Sbjct: 734  RGGETPEGLATSVVHYGAGAKELG-----------AFLQKSPPP----PPPTAQSTQPTP 778

Query: 702  NDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVT 761
            +   G   E G         P    L+ S    A + SP+   V   LL      PAT  
Sbjct: 779  H---GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL-----EPATRD 830

Query: 762  NLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGG 821
                  P    P PP    +       G        A   P       +  PGA+ +  G
Sbjct: 831  GAPQPPPPPPPPPPPMPLQLEAHLRSHGLEP-----AAPSPRLRPEESLDPPGAMQELLG 885

Query: 822  ITQVQYILPTLPQQLQVAPAPA----PAPGTKAAAPSGP-----APTTSIRFTLPPGTST 872
              +    LP  P    V P  +    PA   ++ +P G       P TSI F        
Sbjct: 886  ALEP---LPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDE 942

Query: 873  NGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMS 932
                        G         A PP+ +      A PP       PG        P   
Sbjct: 943  ERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPP-------PGPPAYDPYGPYCP 995

Query: 933  VRGGGAGQPLPLV----SPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPG 988
             R  GAG   P +    + P  +P    A+P   +IQ  P   + P    PP  P   P 
Sbjct: 996  GRASGAGPETPGLGLDPNKPPELPSTVNAEPLG-LIQSGPHQAAPP----PPPPPPPPPA 1050

Query: 989  PTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPS 1048
            P S+P+                GG   P+  S    +    +S          F  L   
Sbjct: 1051 PASEPK----------------GGLTSPIFCSTKPKKLLKTSS----------FHLLRRR 1084

Query: 1049 GPAFVQPL--------LSAGQAPLLAPGQVGVSPVPSPQLPPACAA-------------- 1086
             P F  P           A +     P  + ++P   P L  +C +              
Sbjct: 1085 DPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCP 1144

Query: 1087 ----PGGP------VITAFYSGSPAPTSS---APLAQPSQAPPSLVYTVATSTTPPAATI 1133
                P GP         A   G P P       PL  P+ A P+   T       P    
Sbjct: 1145 PNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRG 1204

Query: 1134 LPKGPPAPATATP--APTSPF------PSATAG-------------------SMTYSLVA 1166
              +G  A         P  P       P A  G                   S+T   + 
Sbjct: 1205 RGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIE 1264

Query: 1167 PKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQ-----PLEPGPVREPTAPES 1221
             K +    K P+     +AS      +   SG+  P   Q     PL P     P+ P  
Sbjct: 1265 AKIKEVEEKQPEMKSGFMASF----LDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPAR 1320

Query: 1222 ELEGQP--TP--PAPPP---------LPETWTPTARSSPPLPPPAEERTSAKGPETMASK 1268
             L+ QP  TP  P PPP         L    +       P P    +    +  ET+ S 
Sbjct: 1321 GLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPS- 1379

Query: 1269 FPSSSSDWRVPGQGLENR--------GEPP--------TPPSPAPAPAVA-------PGG 1305
            F S   D     + L+           +PP        TP  P  APA A       PG 
Sbjct: 1380 FSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGL 1439

Query: 1306 SSESSSGRAAGDTPERK------EAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERF 1359
             S +S+G       E K       A     +    PPP +    S    V          
Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLV---------- 1489

Query: 1360 AELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPK-------- 1411
            A  P   P   LP P   ++ + P             +  L + PE+P +P         
Sbjct: 1490 APTPSSPPPPPLPPPPPPAMPSPP-------PPPPPAAAPLAAPPEEPAAPSPEDPELPD 1542

Query: 1412 -------RKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLG---ELEYDKVPYS 1461
                   +K    + C         +  EG     D     AED+      L+  + P  
Sbjct: 1543 TRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPP 1602

Query: 1462 SLRRTLDQRRALVMQLFQDHGFFPSAQ-------ATAAFQARYADIFPSKVCLQLKIREV 1514
              R     ++AL+ +      F P  +       AT+ +   + D       L +K  E 
Sbjct: 1603 IWR----VQKALLQK------FTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLEN 1652

Query: 1515 RQK----IMQAATPTEQPP-----GAEAPLPV-------PPPTGTAAAPAPTPSPAGGPD 1558
              K     + A  P  +PP       +A  PV       PPP     APAP P P     
Sbjct: 1653 VNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPP----KAPAPPPKPETPEK 1708

Query: 1559 PTSPSSDSGTAQAAPPLPPPPE 1580
             TS      T + A P PP PE
Sbjct: 1709 TTSEKPPEQTPETAMPEPPAPE 1730



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 254/1122 (22%), Positives = 341/1122 (30%), Gaps = 242/1122 (21%)

Query: 642  GGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASP 701
            G G     +   SL YG+     SR +      + R   + P P+ S          A+ 
Sbjct: 17   GAGWSYERSAKASLVYGS-----SRTSHPETDILHRQAYAAPHPLQSY---------ATN 62

Query: 702  NDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVT 761
            +  AG      TG    G +    S V +   +  +  P P   A  LL    ++P+  T
Sbjct: 63   HHPAGLSGLFDTGLHHAGSAGPDAS-VMNLISALESRGPQPGPSASSLLSQF-RSPSWQT 120

Query: 762  NLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGA--------GAGSGPNGPVP--LGIL 811
             +   TPG      P   FI+   PG  T   S A          GS P  PVP  L + 
Sbjct: 121  AM--HTPG------PTELFISGALPGSSTFPSSSALSAYQHPASFGSRPF-PVPSSLSLQ 171

Query: 812  QPGALGKAGGITQVQYILPTLPQQLQVAPA-------------------PAPAPGTKAAA 852
             P     A G+     +L   P Q    P+                   PA  P  +   
Sbjct: 172  DPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGP 231

Query: 853  PSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSV--------- 903
            P  P P   +        S++    AA   +P +         PPP  +++         
Sbjct: 232  PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH 291

Query: 904  ----SPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGG------GAGQPLPLVSPPFSVPV 953
                +  Q PPP   A  L   +    + PSM  R        G G+P P    P     
Sbjct: 292  YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGP 351

Query: 954  QNGAQPPS----------------------KIIQLTPVPVSTPSGLVPPLSPATLPGPTS 991
                   S                       IIQ +P   +   G       AT P P  
Sbjct: 352  SGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQ-SPGYKTGKGGYGAAAGGATRPPP-- 408

Query: 992  QPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGT-VTSYGPTSSVALGFTSLGPSGP 1050
                   P ST     QS GG A    T  AS   G    +Y P     L    LGP   
Sbjct: 409  -------PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGL----LGPQ-- 455

Query: 1051 AFVQPLLSAGQAPLL--APGQVGVSPVPSPQLPPACAAPGGPVITAFYS----------- 1097
            A+ Q     GQA  L  AP   G      P  PP+   P G      YS           
Sbjct: 456  AYGQG-FGGGQAQDLSKAPSYSG-----GPPQPPSGPPPPGLATCQSYSPDQLQGQLYGV 509

Query: 1098 -GSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSAT 1156
             G P P  +A       A PSL Y+   S   PA +    G        P+       A+
Sbjct: 510  QGEPYPGPAAHSQGLPTASPSLSYSTGHS---PALSGHGGG------WGPSSLGGGGEAS 560

Query: 1157 AGSMTYSLVAPKAQ-RP----SPKAPQK-VKAAIASIP------VGSFEAGASGRPGPAP 1204
               +   L +P A  RP    SP AP K + + +AS P       GS+ AGA G  G   
Sbjct: 561  PSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD 620

Query: 1205 RQPLEPGPVREPT--APESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGP 1262
               L  GP   P     + E   Q    AP             SPP    A+      G 
Sbjct: 621  GSELLAGPGGPPAERTEDEEFLIQHLLQAP-------------SPPRTSGADGLVGEDGA 667

Query: 1263 ETMASKFPSSSSDWRVPGQGLENRGEPP--------------TPPSPAPAPAVAPGGSSE 1308
               +     S      PG   E   E P                     A  +  G   E
Sbjct: 668  ADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKE 727

Query: 1309 SSSG-RAAGDTPE------------RKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDF 1355
               G    G+TPE             KE     +K    PPP  ++     + +L E   
Sbjct: 728  KKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGG 787

Query: 1356 EERFAELPEFRPEEVLPSPTLQSLATSPRA------ILGSYRKKRKNSTDLDSAPEDPTS 1409
             +    LP   P ++LPS    + + SP A      +L    +           P  P  
Sbjct: 788  PDLPLVLPP-PPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPM 846

Query: 1410 PKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELE-YDKVPYSSLRRTLD 1468
            P +      S   EP  P       +  + D  G   +++LG LE     P  +     +
Sbjct: 847  PLQLEAHLRSHGLEPAAPSPRLRPEE--SLDPPGA-MQELLGALEPLPPAPGDTGVGPPN 903

Query: 1469 QRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQP 1528
                     ++     PS Q T A   R+  +  + +C    + +  ++           
Sbjct: 904  SEGKDPAGAYRS----PSPQGTKA--PRFVPL--TSICFPDSLLQDEERSFFPTMEEMFG 955

Query: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPAGGP---DPTSPSSDSGTAQAAPPLP-------PP 1578
             GA        P      P     P  GP   DP  P      + A P  P        P
Sbjct: 956  GGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKP 1015

Query: 1579 PE--------------SGPGQPGWEGAPQPSPPPPGPSTAAT 1606
            PE              SGP Q     AP P PPPP P   A+
Sbjct: 1016 PELPSTVNAEPLGLIQSGPHQ----AAPPPPPPPPPPPAPAS 1053



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/83 (36%), Positives = 33/83 (39%), Gaps = 14/83 (16%)

Query: 1521 AATPTEQPPGAEAP----LPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLP 1576
            A TP  QPP    P    LP PPP       +P P P   P P         A  +PP P
Sbjct: 1464 APTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPP--------PAMPSPPPP 1515

Query: 1577 PPPESGP--GQPGWEGAPQPSPP 1597
            PPP + P    P    AP P  P
Sbjct: 1516 PPPAAAPLAAPPEEPAAPSPEDP 1538



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 96/413 (23%), Positives = 123/413 (29%), Gaps = 67/413 (16%)

Query: 968  PVPVSTPSGLVPPLSPAT-LPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSP-ASSQ 1025
            P   STP G  PPL+PA  +PGP   P    LPS+      +       P  T P A + 
Sbjct: 1413 PKDTSTPDG--PPLAPAAAVPGPPPLPG---LPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467

Query: 1026 AGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLP---- 1081
                    P    AL      PS P  V P  S+   P L P      P P P  P    
Sbjct: 1468 QPQPPPPPPPPQPAL------PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAA 1521

Query: 1082 PACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAP-------------------------- 1115
            P  A P  P   +        T    LA+  +                            
Sbjct: 1522 PLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFV 1581

Query: 1116 ------PSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAP-K 1168
                  PSL   + T   PP    + K      T           AT+  + Y   A  +
Sbjct: 1582 IRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNR 1641

Query: 1169 AQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLE-PGPVREPTAPESELEGQP 1227
             QR   K  + V           +    + +P   P  P+   G  + P +        P
Sbjct: 1642 YQRLYVKFLENVNKK-------DYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPP 1694

Query: 1228 TPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRG 1287
              PAPPP PET   T    PP   P         PE  +   P      +        RG
Sbjct: 1695 KAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEK----VTRG 1750

Query: 1288 EPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKK 1340
            E P     A +     G  +      A G     +       KVK  PPP K+
Sbjct: 1751 ERPLRGERATS-----GRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKR 1798



 Score = 39.3 bits (90), Expect = 0.031
 Identities = 51/194 (26%), Positives = 66/194 (34%), Gaps = 42/194 (21%)

Query: 1098 GSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATA 1157
            GS AP   AP   P    P       TS  PP  T        P TA P P +P      
Sbjct: 1688 GSSAPPPKAPAPPPKPETPEKT----TSEKPPEQT--------PETAMPEPPAP------ 1729

Query: 1158 GSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPL---EPGPVR 1214
                     P   RP  K  +K K      P+   E   SGR    P + L   +P   R
Sbjct: 1730 -------EKPSLLRPVEKEKEKEKVTRGERPLRG-ERATSGRQ-TRPERSLATGQPATSR 1780

Query: 1215 EPTAPESELEGQPTPPAPPPLPETWTPTARSSPPL--PPPAEERTSAKGPETMASKFPSS 1272
             P A  ++++ +P    PP   + W   A  +      PP     S   P         S
Sbjct: 1781 LPKARPTKVKAEP----PPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGA------PS 1830

Query: 1273 SSDWRVPGQGLENR 1286
              +  VPG+ L+ R
Sbjct: 1831 EDERAVPGRLLKTR 1844



 Score = 37.7 bits (86), Expect = 0.090
 Identities = 43/180 (23%), Positives = 58/180 (32%), Gaps = 29/180 (16%)

Query: 36   PWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAH--ERPPGGTGSAD 93
            PWH          P P  +  +A+ P S   A   S  P ++ A     E P   T    
Sbjct: 1666 PWHR--------PPVPVRRSGQAKNPVS---AGGSSAPPPKAPAPPPKPETPEKTTSEKP 1714

Query: 94   PERPPGATCPESPGPGPPHPLGVVESGKGPPPTT--------EEEASGPPGEPRLDSETE 145
            PE+ P    PE P P  P  L  VE  K     T        E   SG    P     T 
Sbjct: 1715 PEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATG 1774

Query: 146  SDHDDAFLSIMSPEIQLPLPPGKRR--------TQSLSALPKERDSSSEKDGRSPNKREK 197
                         +++   PP KR+          +    P    S SE    +P++ E+
Sbjct: 1775 QPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDER 1834



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 42/161 (26%), Positives = 55/161 (34%), Gaps = 36/161 (22%)

Query: 42   PFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPP-GA 100
            P L   +P P+  P+   QP   P                   PP     A P  PP  A
Sbjct: 1450 PPLLEEKPPPTPPPAPTPQPQPPP-------------------PPPPPQPALPSPPPLVA 1490

Query: 101  TCPESPGPG---PPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMS 157
              P SP P    PP P   + S   PPP      + PP EP   S  +            
Sbjct: 1491 PTPSSP-PPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED------------ 1537

Query: 158  PEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKD 198
            PE+    P    + Q  +A+  E D  + + G     RE+D
Sbjct: 1538 PELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERD 1578



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 27/79 (34%), Positives = 28/79 (35%), Gaps = 12/79 (15%)

Query: 1520 QAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPP 1579
            Q A P+  P  A  P   PPP      P   PSP   P P           AA PL  PP
Sbjct: 1479 QPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP-----------AAAPLAAPP 1527

Query: 1580 ESGPGQPGWEGAPQPSPPP 1598
            E  P  P  E    P   P
Sbjct: 1528 EE-PAAPSPEDPELPDTRP 1545



 Score = 35.8 bits (81), Expect = 0.34
 Identities = 42/157 (26%), Positives = 58/157 (36%), Gaps = 27/157 (17%)

Query: 66   VASNQSKEPAESAAV-AHERPP--GGTGSADPERPPGATCPESPGPGPPHPLGVVESGKG 122
            VA N+  + + S+A+ A + PP  G   ++ P+ PP A     PGP P   L    S   
Sbjct: 1388 VAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGT 1447

Query: 123  PPPTTEEEASGP-----------------------PGEPRLDSETESDHDDAFL-SIMSP 158
            P P   EE   P                       P  P L + T S      L     P
Sbjct: 1448 PEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP 1507

Query: 159  EIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKR 195
             +  P PP       L+A P+E  + S +D   P+ R
Sbjct: 1508 AMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTR 1544



 Score = 34.7 bits (78), Expect = 0.76
 Identities = 63/281 (22%), Positives = 96/281 (34%), Gaps = 42/281 (14%)

Query: 1169 AQRPSPKAPQKVK-AAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQP 1227
            A++P  + P  V+ +  A  PV      A G   P P+ P  P     P    SE   + 
Sbjct: 1663 ARKPWHRPPVPVRRSGQAKNPVS-----AGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQ 1717

Query: 1228 TP------PAPPPLPETWTPTARSSP-------PLPPPAEERTSAKGPETMASKFPSSSS 1274
            TP      P  P  P    P  +            P   E  TS +      S      +
Sbjct: 1718 TPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPA 1777

Query: 1275 DWRVP-GQGLENRGEPPTPP---------SPAPAPAVAPGGSSESSSGRAAGDTPERKEA 1324
              R+P  +  + + EPP              A A    PG SS+S S   A   P   E 
Sbjct: 1778 TSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGA---PSEDER 1834

Query: 1325 AGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPR 1384
            A  G+ +K R   +++ + S    ++S     +    L +   E  LP            
Sbjct: 1835 AVPGRLLKTR--AMREMYRSYVEMLVSTALDPDMIQALEDTHDELYLPP------MRKID 1886

Query: 1385 AILGSYRKKRKNSTDLDSAPEDP--TSPKRKMRRRSSCSSE 1423
             +L  ++KK      L  A +D   T P+ ++ +    S E
Sbjct: 1887 GLLNEHKKKVLKRLSLSPALQDALHTFPQLQVEQSGEGSPE 1927



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 47/173 (27%), Positives = 60/173 (34%), Gaps = 31/173 (17%)

Query: 601  KRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKE--------------------EQ 640
            K P S GG   P P   A PP        T   PP +                     E+
Sbjct: 1681 KNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEK 1740

Query: 641  EGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEAS 700
            E    +V     P     A +   +RP  ++ T   +P +S       K  PT  +AE  
Sbjct: 1741 EKEKEKVTRGERPLRGERATSGRQTRPERSLATG--QPATSR----LPKARPTKVKAEPP 1794

Query: 701  PNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSA-AATSPAPHLVAGPLLGT 752
            P        E G G+   GG P G S   SD +S+  A S     V G LL T
Sbjct: 1795 PKKRKKWLKEAG-GNATAGGGPPGSS---SDSESSPGAPSEDERAVPGRLLKT 1843



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 22/77 (28%)

Query: 85   PPGGTGSADPERP--PGATC---PESPGPG-----PPH--------PLGVVESG----KG 122
            PP G  + DP  P  PG      PE+PG G     PP         PLG+++SG      
Sbjct: 980  PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAP 1039

Query: 123  PPPTTEEEASGPPGEPR 139
            PPP        P  EP+
Sbjct: 1040 PPPPPPPPPPAPASEPK 1056



 Score = 31.6 bits (70), Expect = 6.5
 Identities = 37/143 (25%), Positives = 54/143 (37%), Gaps = 11/143 (7%)

Query: 887  PILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVS 946
            P+     SAPPPKA       APPP             P   P  ++    A +   L+ 
Sbjct: 1683 PVSAGGSSAPPPKA------PAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLR 1736

Query: 947  PPFSVPVQ---NGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLL--PSS 1001
            P      +      + P +  + T    + P   +    PAT   P ++P KV    P  
Sbjct: 1737 PVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPK 1796

Query: 1002 TRITYVQSAGGHALPLGTSPASS 1024
             R  +++ AGG+A   G  P SS
Sbjct: 1797 KRKKWLKEAGGNATAGGGPPGSS 1819


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  106 bits (264), Expect = 2e-22
 Identities = 227/892 (25%), Positives = 273/892 (30%), Gaps = 138/892 (15%)

Query: 512  PEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFK------AQESGQG 565
            P PPGPP PP   G G   AP  S      S+   +    +G    +           QG
Sbjct: 141  PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG 200

Query: 566  STAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGG 625
                P  P  PGA GP  P         +       +P   G   PPGP      P   G
Sbjct: 201  FQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260

Query: 626  NILQTLVLPPNKEEQEGG---GARVPSAPA-PSLAYGAP---AAPLSRPAATMVTNVVRP 678
                   LP  K  +      GA+  + PA P    G+P    AP       +     RP
Sbjct: 261  -------LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP 313

Query: 679  VSSTP---------VPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVY 729
             +  P            A  P PT            GA+ E G         P GV    
Sbjct: 314  GAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEP 373

Query: 730  SDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGY-GAPAPPAVQFIAQGAPGG 788
                 A A  PA +  A    G  G   A     + G PG+ GA  P   Q    G P G
Sbjct: 374  GPPGPAGAAGPAGNPGAD---GQPGAKGANGAPGIAGAPGFPGARGPSGPQ--GPGGPPG 428

Query: 789  --GTTAGSGAGAGSGPNG----PVPLGILQP----GALGKAGGITQVQYILPTLPQQLQV 838
              G +   GA    G  G    P P+G+  P    G  GK G   +        P  L  
Sbjct: 429  PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG------PTGLPG 482

Query: 839  APAPAPAPGTK-------AAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQS 891
             P     PG++        A P GPA          P  S         A  PG   L  
Sbjct: 483  PPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTG 542

Query: 892  VPSAPPPKAQSVSPVQA---------PPPGGSAQL----LPGKVLVPLAAPSMSVRGGGA 938
             P +P P  ++  P  A          PPG   Q      PG    P  A     + G  
Sbjct: 543  SPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG----PKGAAGEPGKAGER 598

Query: 939  GQP-LPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVL 997
            G P  P    P     + GAQ P       P P   P+G      PA  PG    P    
Sbjct: 599  GVPGPPGAVGPAGKDGEAGAQGP-------PGPAG-PAGERGEQGPAGSPGFQGLPGPAG 650

Query: 998  LPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLL 1057
             P        Q   G     G S A  + G     G            GP GPA   P  
Sbjct: 651  PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ----------GPPGPA--GPRG 698

Query: 1058 SAGQAPLLAPGQVGV-SPVPSPQLPPACAAPG--GPVITAFYSGSPAPTSSAPLAQPSQA 1114
            + G     APG  G      +P  P +  APG  G       +G P P      A P  A
Sbjct: 699  ANG-----APGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753

Query: 1115 PPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSP 1174
              S         T P       GPP PA A        PS  AG             P P
Sbjct: 754  DGSPGKDGVRGLTGPI------GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGP 807

Query: 1175 KAPQKVKAAIASIPVGSFEAGASGRPG----------PAPRQPL-EPGPVREPTAPESE- 1222
              P    A  A  P    + GA G PG          P P  P   PGP+    AP ++ 
Sbjct: 808  PGP----AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863

Query: 1223 LEGQPTPPAPPPLPETW------TPTARSSPPLPPPAEERTSAKGP--ETMASKFPSSSS 1274
              G   PP     P          P+  + PP PP    +   KGP  ET  +  P    
Sbjct: 864  ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923

Query: 1275 DWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAG 1326
                PG      GE  +P +  PA A    G    +  R     P ++   G
Sbjct: 924  PPGPPGPA----GEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERG 971



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 259/1066 (24%), Positives = 317/1066 (29%), Gaps = 236/1066 (22%)

Query: 345  GGPGSAR-PRAFSHSGVHSLDGGEVDSQALQELTQMVS----GPASYSGPK----PSTQY 395
            G PG+A  P    H G   LDG + D+       +  S    G     GP+       + 
Sbjct: 254  GLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP 313

Query: 396  GAPGPFAAPGEGGALAATGRP--------PLLPTRASRSQRAASEDMTSDEERMVICEEE 447
            GAPGP  A G  GA  A G P        P  P        A  +     E    +  E 
Sbjct: 314  GAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEP 373

Query: 448  GDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSS--FTH 505
            G        G                  +G+   +   G KG      +P I  +  F  
Sbjct: 374  GPPGPAGAAG-----------------PAGNPGADGQPGAKGANG---APGIAGAPGFPG 413

Query: 506  CRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQG 565
             R P  P+ PG P  P    KG    P +  S   + +        +      A E G+ 
Sbjct: 414  ARGPSGPQGPGGPPGP----KGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR 469

Query: 566  STAGPLRP-----PPPGAGGPAT---PSKATRFLPMDPATFRRKRPESVGGLEPPG---- 613
               G   P     PP   GGP +   P       P  PA   R  P   G    PG    
Sbjct: 470  GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG-ERGSPGPAGPKGSPGEAGR 528

Query: 614  ------PSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYG--------A 659
                  P       S G         PP    Q+G     P  P P  A G         
Sbjct: 529  PGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGR----PGPPGPPGARGQAGVMGFPG 584

Query: 660  PAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPG 719
            P      P       V  P  +  V  A K      +    P   AG R E G     P 
Sbjct: 585  PKGAAGEPGKAGERGVPGPPGA--VGPAGKDGEAGAQGPPGPAGPAGERGEQG-----PA 637

Query: 720  GSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQ 779
            GSP    L         A  P    V G L G  G + A       G  G   P  PA  
Sbjct: 638  GSPGFQGLPGPAGPPGEAGKPGEQGVPGDL-GAPGPSGARGERGFPGERGVQGPPGPAGP 696

Query: 780  FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGIL-QPGALGKAG------------------ 820
              A GAPG     G  AGA   P      G+   PG  G AG                  
Sbjct: 697  RGANGAPGNDGAKGD-AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADG 755

Query: 821  --GITQVQYILPTLPQQLQVAPAPAPAPGTKA-AAPSGPAPTTSIRFTLPPGTSTNGKVL 877
              G   V+ +   +       P PA APG K  + PSGPA  T  R              
Sbjct: 756  SPGKDGVRGLTGPIGP-----PGPAGAPGDKGESGPSGPAGPTGAR-------------- 796

Query: 878  AATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRG-- 935
                   G P  +  P  P P         A PPG   Q  PG    P  A +    G  
Sbjct: 797  -------GAPGDRGEPGPPGPAGF------AGPPGADGQ--PGAKGEPGDAGAKGDAGPP 841

Query: 936  ---GGAGQPLPL--VSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPT 990
               G AG P P+  V  P +   +  A PP      T  P +  +G V P  P+   GP 
Sbjct: 842  GPAGPAGPPGPIGNVGAPGAKGARGSAGPPGA----TGFPGA--AGRVGPPGPSGNAGPP 895

Query: 991  SQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFT--SLGPS 1048
              P                 GG   P G +  + + G V   GP        +  + GP+
Sbjct: 896  GPPGPA-----------GKEGGKG-PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPA 943

Query: 1049 G-PAFVQPLLSAGQAPLLA-PGQVGVSPVPSPQLPPACAAPG--GPVITAFYSGSPAPTS 1104
            G P    P   AGQ  ++  PGQ G    P   LP     PG  GP   +   G P P  
Sbjct: 944  GAPGTPGPQGIAGQRGVVGLPGQRGERGFPG--LPGPSGEPGKQGPSGASGERGPPGPMG 1001

Query: 1105 SAPLAQPS-----QAPPSLVYTVATSTTPPAATILPK-GPPAPATATPAPTSPFPSATAG 1158
               LA P      +  P    +     +P A     + GP  P  A  AP +P P   AG
Sbjct: 1002 PPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAG 1061

Query: 1159 SMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPA-PRQPLEPGPVREPT 1217
                                              ++G  G  GPA P  P+ P   R P 
Sbjct: 1062 ----------------------------------KSGDRGETGPAGPAGPVGPVGARGPA 1087

Query: 1218 APESE--------------------LEGQPTPPAPPPLPETWTPTARSSP--PLPPPAEE 1255
             P+                        G   PP PP  P    P+  S P  P  PP   
Sbjct: 1088 GPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA 1147

Query: 1256 RTSAK-GPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPA 1300
                K G   +           R    G      PP PP P   P+
Sbjct: 1148 GAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS 1193



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 200/779 (25%), Positives = 241/779 (30%), Gaps = 117/779 (15%)

Query: 575  PPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLP 634
            P G  GPA P              R   P   G   PPGP     PP  GGN    L   
Sbjct: 119  PRGPRGPAGPPG------------RDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSY- 165

Query: 635  PNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTS 694
               +E+  GG  VP    PS   G P  P     A        P      P AS P    
Sbjct: 166  -GYDEKSTGGISVPGPMGPSGPRGLPGPP----GAPGPQGFQGPPGEPGEPGASGPM--G 218

Query: 695  GRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVG 754
             R    P    G   E G   R     P G         +A       H     L G  G
Sbjct: 219  PRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKG 278

Query: 755  KAPATVTNLLVGTPGY-GAPAPPAVQFIA-----QGAPG-GGTTAGSGAGAGSGPNGPV- 806
             A         G+PG  GAP     + +       GAPG  G     GA   +GP GP  
Sbjct: 279  DAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTG 338

Query: 807  ---PLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIR 863
               P G   PGA+G  G            PQ ++  P P P P   A     P       
Sbjct: 339  PAGPPGF--PGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAGPAGNPGADGQ-- 393

Query: 864  FTLPPGTSTNGKVLAATAPT-PGI--PILQSVPSAPP-PKAQSVSPVQAPPPGGS-AQLL 918
               P     NG    A AP  PG   P     P  PP PK  S  P      G + A+  
Sbjct: 394  ---PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGE 450

Query: 919  PGKVLV--PLAAPSMSVRGGGAGQPLP--LVSPPFSVPVQNGAQPPSKIIQLTPVPVSTP 974
            PG V V  P        + G  G+P P  L  PP           P       P   +  
Sbjct: 451  PGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE 510

Query: 975  SGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGP 1034
             G   P  P   PG   +P +  LP +  +T    + G     G    + Q G     GP
Sbjct: 511  RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP 570

Query: 1035 TSSVA----LGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGP 1090
              +      +GF   GP G        +AG+     PG+ G   VP P   P    P G 
Sbjct: 571  PGARGQAGVMGFP--GPKG--------AAGE-----PGKAGERGVPGP---PGAVGPAGK 612

Query: 1091 VITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTS 1150
               A   G P P   A                      PA +   +G P PA        
Sbjct: 613  DGEAGAQGPPGPAGPAG---------------ERGEQGPAGSPGFQGLPGPAG------- 650

Query: 1151 PFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEP 1210
              P   AG      V      P P   +  +           E G  G PGPA  +    
Sbjct: 651  --PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG-------ERGVQGPPGPAGPRGANG 701

Query: 1211 GPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFP 1270
             P  +    ++   G P     P L     P  R +  LP P  +R  A GP+       
Sbjct: 702  APGNDGAKGDAGAPGAPGSQGAPGLQGM--PGERGAAGLPGPKGDRGDA-GPKG------ 752

Query: 1271 SSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGK 1329
            +  S  +   +GL       T P   P PA APG   ES     AG T  R      G+
Sbjct: 753  ADGSPGKDGVRGL-------TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGE 804



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 212/876 (24%), Positives = 260/876 (29%), Gaps = 169/876 (19%)

Query: 346  GPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPG 405
            GPG   P    +SG     G + D+ A  E      GP    GP        PGP    G
Sbjct: 422  GPGGP-PGPKGNSGEPGAPGSKGDTGAKGE-----PGPVGVQGP--------PGPAGEEG 467

Query: 406  EGGALAATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDG-FGTTDID 464
            + GA    G P  LP          S                G D V    G  G     
Sbjct: 468  KRGARGEPG-PTGLPGPPGERGGPGSRGFP------------GADGVAGPKGPAGERGSP 514

Query: 465  LKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAF 524
                 + +  E+G        G KG      SP          P      PGPP PP A 
Sbjct: 515  GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574

Query: 525  G----------KGYGSAPSSS----------ASSPASSSASAATSFSLGSGTFKAQESGQ 564
            G          KG    P  +          A  PA     A      G      +   Q
Sbjct: 575  GQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQ 634

Query: 565  GSTAGPLRPPPPGAGGPATPSKATR----FLPMD-----PATFRRKR--PESVGGLEPPG 613
            G    P     PG  GP  P +A +     +P D     P+  R +R  P   G   PPG
Sbjct: 635  GPAGSPGFQGLPGPAGP--PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPG 692

Query: 614  PSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVT 673
            P   A P    G        P N   +   GA  P AP    A G    P  R AA +  
Sbjct: 693  P---AGPRGANG-------APGNDGAKGDAGA--PGAPGSQGAPGLQGMPGERGAAGL-- 738

Query: 674  NVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKK 733
                            P P   R +A P    G+  + G         P G +    DK 
Sbjct: 739  ----------------PGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKG 782

Query: 734  SAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPG-YGAPAPPAVQFIAQGAPGG-GTT 791
             +  + PA         G  G   A       G PG  G   PP     A G PG  G  
Sbjct: 783  ESGPSGPA---------GPTGARGAPGDRGEPGPPGPAGFAGPPG----ADGQPGAKGEP 829

Query: 792  AGSGAGAGSGPNGPV-PLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKA 850
              +GA   +GP GP  P G   PG +G  G             +  + +  P  A G   
Sbjct: 830  GDAGAKGDAGPPGPAGPAG--PPGPIGNVGAPGA---------KGARGSAGPPGATGFPG 878

Query: 851  AA----PSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPV 906
            AA    P GP+          P     GK         G P     P  P P  +  SP 
Sbjct: 879  AAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPG 938

Query: 907  QAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQL 966
               P G      PG   +      + + G    +  P +  P   P + G          
Sbjct: 939  ADGPAGAPGT--PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQG---------- 986

Query: 967  TPVPVSTPSGLVPPLSPATLPGPTSQ------PQKVLLPSSTRITYVQSAGGHALPLGTS 1020
             P   S   G   P+ P  L GP  +      P     P        +   G   P G  
Sbjct: 987  -PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPP 1045

Query: 1021 PASSQAGTVTSYGPTS-SVALGFTSLGPSGPAF-VQPLLSAGQAPLLAP----------- 1067
             A    G     GP   S   G T  GP+GPA  V P+ + G A    P           
Sbjct: 1046 GAPGAPGAPGPVGPAGKSGDRGET--GPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103

Query: 1068 -----GQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQP---SQAPPSLV 1119
                 G  G S +  P  PP      GP   +  +G   P  SA        +  P  + 
Sbjct: 1104 DRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIG 1163

Query: 1120 YTVATSTTPPAATILPKGPPAPATATPAPTSPFPSA 1155
                   T  A  + P GPP P    P P  P PSA
Sbjct: 1164 PPGPRGRTGDAGPVGPPGPPGP----PGPPGP-PSA 1194



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 210/906 (23%), Positives = 267/906 (29%), Gaps = 198/906 (21%)

Query: 277  SSSEAKPTSLGLAG----GHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPG 332
            + ++ +P  +G+ G      +E +  +  E G    PG   E     ++    +D  A G
Sbjct: 445  TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA-G 503

Query: 333  SSSCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPK-P 391
                  ER    G PG A P+          + G   ++ L   +    GP   +GP  P
Sbjct: 504  PKGPAGER----GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTG-SPGSPGPDGKTGPPGP 558

Query: 392  STQYGAPGPFAAPGEGGAL---------AATGRPPLLPTRASRSQRAASEDMTSDEERMV 442
            + Q G PGP   PG  G            A G P     R       A      D E   
Sbjct: 559  AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA 618

Query: 443  --------ICEEEGDDDVIADDGF-------GTTDIDLKCKERVTDSESGDSSGEDPEGN 487
                       E G+       GF       G      K  E+    + G        G 
Sbjct: 619  QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678

Query: 488  KGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAA 547
            +GF      P  R             PPGP  P  A G          A +P +  +  A
Sbjct: 679  RGF------PGERGV---------QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGA 723

Query: 548  TSFSLGSGTFKAQ----------------------ESGQGSTAGPLRPPPPGAGGPATPS 585
                   G   A                       + G     GP+ PP P AG P    
Sbjct: 724  PGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP-AGAPGDKG 782

Query: 586  KATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGA 645
            ++    P  P T  R  P   G   PPGP+  A PP   G        P  K E    GA
Sbjct: 783  ESGPSGPAGP-TGARGAPGDRGEPGPPGPAGFAGPPGADGQ-------PGAKGEPGDAGA 834

Query: 646  RVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTA 705
            +  + P        PA P   P               P+     P     R  A P    
Sbjct: 835  KGDAGPP------GPAGPAGPPG--------------PIGNVGAPGAKGARGSAGP---P 871

Query: 706  GARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLV 765
            GA    G   RV    P           S  A  P P    GP     GK P   T    
Sbjct: 872  GATGFPGAAGRVGPPGP-----------SGNAGPPGP---PGPAGKEGGKGPRGETG-PA 916

Query: 766  GTPG-YGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGIL-QPGALGKAGGIT 823
            G PG  G P PP         P G   +    G    P  P P GI  Q G +G  G   
Sbjct: 917  GRPGEVGPPGPP--------GPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPG--Q 966

Query: 824  QVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPT 883
            + +   P LP          P+  +    P GP     +    PPG S            
Sbjct: 967  RGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGL--AGPPGES-------GREGA 1017

Query: 884  PGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLP 943
            PG         +P  K        A PPG               AP      G  G P P
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPG---------------AP------GAPGAPGP 1056

Query: 944  LVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTR 1003
             V P      +    P      + PV    P+G   P  P    G T +           
Sbjct: 1057 -VGPAGKSGDRGETGPAGPAGPVGPVGARGPAG---PQGPRGDKGETGEQGD-------- 1104

Query: 1004 ITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAP 1063
                +   GH    G        G+    GP+        + GP+GP    P  SAG   
Sbjct: 1105 ----RGIKGHRGFSGLQGPPGPPGSPGEQGPSG-------ASGPAGPR--GPPGSAG--- 1148

Query: 1064 LLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVA 1123
              APG+ G++ +P P  PP    P G    A   G P P    P   P   PPS  +  +
Sbjct: 1149 --APGKDGLNGLPGPIGPP---GPRGRTGDAGPVGPPGP--PGPPGPP--GPPSAGFDFS 1199

Query: 1124 TSTTPP 1129
                PP
Sbjct: 1200 FLPQPP 1205



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 186/801 (23%), Positives = 227/801 (28%), Gaps = 154/801 (19%)

Query: 74   PAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEA-- 131
            P E         PG  G A P+ P G    E   PGP  P G       P       A  
Sbjct: 484  PGERGGPGSRGFPGADGVAGPKGPAG----ERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539

Query: 132  -SGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGR 190
             +G PG P  D +T             P    P PPG R    +   P  + ++ E    
Sbjct: 540  LTGSPGSPGPDGKTGPPGPAGQDGRPGP----PGPPGARGQAGVMGFPGPKGAAGE---- 591

Query: 191  SPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYH 250
             P K  +  +  P  A     K   A   Q  P        +  GE   A  P       
Sbjct: 592  -PGKAGERGVPGPPGAVGPAGKDGEAGA-QGPPGPAGPAGER--GEQGPAGSPG------ 641

Query: 251  DLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSM-SETGTAAAP 309
                      F+  P       +  K   +  P  LG  G      ER    E G    P
Sbjct: 642  ----------FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP 691

Query: 310  GVSSELLSVAA--QTLLSSDTKAPGS-SSCGAERLHTVGG-------PGSARPRAFSHSG 359
            G +    +  A        D  APG+  S GA  L  + G       PG    R    +G
Sbjct: 692  GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG--DAG 749

Query: 360  VHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRP-PL 418
                DG       ++ LT  +  P     P    + G  GP    G  GA    G P P 
Sbjct: 750  PKGADGSP-GKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808

Query: 419  LPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGD 478
             P   +    A  +     E         GD     D G                  +G 
Sbjct: 809  GPAGFAGPPGADGQPGAKGEP--------GDAGAKGDAG--------------PPGPAGP 846

Query: 479  SSGEDPEGNKGF-----GRKVFSPVIRSSFTHCRPPLDPEPP----GPPDPPVAFGKGYG 529
            +    P GN G       R    P   + F      + P  P    GPP PP   GK  G
Sbjct: 847  AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906

Query: 530  SAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGP-----ATP 584
              P    + PA            G    K      G    P  P P G  G         
Sbjct: 907  KGPRGE-TGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPG 965

Query: 585  SKATRFLPMDPATFRRKRPESVGGLE----PPGPSVIAAPPSGGGNILQTLVLPPNKEEQ 640
             +  R  P  P        +   G      PPGP     PP   G        PP +  +
Sbjct: 966  QRGERGFPGLPGPSGEPGKQGPSGASGERGPPGP---MGPPGLAG--------PPGESGR 1014

Query: 641  EG--GGARVPSAPAPSLAYG-----APAAPLSRPAATMVTNVVRPVSST-------PVPI 686
            EG  G    P       A G      PA P   P A      V P   +       P   
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074

Query: 687  ASKPFPTSGRAEASPNDTAGARTEMG----------------TGSRVPGGSPLGVSLVYS 730
            A    P   R  A P    G + E G                 G   P GSP        
Sbjct: 1075 AGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP-------G 1127

Query: 731  DKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPG-YGAPAPPAVQFIAQGAPG-G 788
            ++  + A+ P     AGP  G  G A A   + L G PG  G P P       +G  G  
Sbjct: 1128 EQGPSGASGP-----AGP-RGPPGSAGAPGKDGLNGLPGPIGPPGP-------RGRTGDA 1174

Query: 789  GTTAGSGAGAGSGPNGPVPLG 809
            G     G     GP GP   G
Sbjct: 1175 GPVGPPGPPGPPGPPGPPSAG 1195



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 4/78 (5%)

Query: 1525 TEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG-P 1583
            T+  PGAE P     P     + +PT     G +   P  D+G      P  PP   G P
Sbjct: 78   TKNCPGAEVPEGECCPVCPDGSESPTDQETTGVE--GPKGDTGPRGPRGPAGPPGRDGIP 135

Query: 1584 GQPGWEGAPQPSPPPPGP 1601
            GQPG  G P P P PPGP
Sbjct: 136  GQPGLPGPPGP-PGPPGP 152



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 10/83 (12%)

Query: 1523 TPTEQ-PPGAEAPLPVPPPTGTAAAPAPT-----PSPAGGPDPTSPSSDSGTAQAAPPLP 1576
            +P EQ P GA  P     P G+A AP        P P G P P   + D+G     PP P
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAG--PVGPPGP 1182

Query: 1577 PPPESGPGQP--GWEGAPQPSPP 1597
            P P   PG P  G++ +  P PP
Sbjct: 1183 PGPPGPPGPPSAGFDFSFLPQPP 1205



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 16/85 (18%)

Query: 1528 PPGAEAPLPV---PPPTGTAAAPAPT-----PSPAGGPDPTSPSSDSGTAQAAPPLPPPP 1579
            PPGA     V   P P G A  P        P P G   P     ++G     PP P  P
Sbjct: 570  PPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA--QGPPGPAGP 627

Query: 1580 -----ESGP-GQPGWEGAPQPSPPP 1598
                 E GP G PG++G P P+ PP
Sbjct: 628  AGERGEQGPAGSPGFQGLPGPAGPP 652



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 16/93 (17%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAPTPS--PAGGPDPT------SPSSDSGTA----QAAPPL 1575
            PPGA      P   G    P P+ +  P G P P        P  ++G A    +  PP 
Sbjct: 870  PPGATG---FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG 926

Query: 1576 PPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608
            PP P    G PG +G P  +P  PGP   A  R
Sbjct: 927  PPGPAGEKGSPGADG-PAGAPGTPGPQGIAGQR 958



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 30/97 (30%), Positives = 34/97 (35%), Gaps = 27/97 (27%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAPT--------------PSPAGGPDPTSPSSDSGTAQAAP 1573
            PPG   P   P P G   AP                 P  AG   P  PS ++G     P
Sbjct: 840  PPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAG-----P 894

Query: 1574 PLPPPPESGPGQPGWEGAPQPS--------PPPPGPS 1602
            P PP P    G  G  G   P+        P PPGP+
Sbjct: 895  PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPA 931



 Score = 40.8 bits (94), Expect = 0.011
 Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 21/111 (18%)

Query: 45  APSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATC-- 102
           AP Q  P   P E  +P +   A  +  + A  AA     PPG TG A P   PGA    
Sbjct: 297 APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAA----GPPGPTGPAGPPGFPGAVGAK 352

Query: 103 ----PESPG-----------PGPPHPLGVVESGKGPPPTTEEEASGPPGEP 138
               P+ P            PGPP P G       P    +  A G  G P
Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 5/72 (6%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG-PGQ- 1585
            PPGA  P       G    P P   PAG      P+   G      P  PP E+G PG+ 
Sbjct: 603  PPGAVGPAGKDGEAGAQGPPGPA-GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661

Query: 1586 --PGWEGAPQPS 1595
              PG  GAP PS
Sbjct: 662  GVPGDLGAPGPS 673



 Score = 38.9 bits (89), Expect = 0.041
 Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 9/79 (11%)

Query: 1529 PGAEAPLPVPPPTGTAAAPAPT--------PSPAGGPDPTSPSSDSGTAQAAPPLPPPPE 1580
            PG   P  +    G    P           P P+G P    PS  SG      P+ PP  
Sbjct: 946  PGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGL 1005

Query: 1581 SG-PGQPGWEGAPQPSPPP 1598
            +G PG+ G EGAP     P
Sbjct: 1006 AGPPGESGREGAPGAEGSP 1024



 Score = 38.5 bits (88), Expect = 0.053
 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 26/94 (27%)

Query: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW 1588
            PG   P  +P   G   AP P    AG     +  +D  T  A PP P  P   PG PG 
Sbjct: 298  PGQMGPRGLPGERGRPGAPGP----AG-----ARGNDGATGAAGPPGPTGPAGPPGFPGA 348

Query: 1589 EGA-----PQ------------PSPPPPGPSTAA 1605
             GA     PQ              P PPGP+ AA
Sbjct: 349  VGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAA 382



 Score = 38.5 bits (88), Expect = 0.053
 Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 7/81 (8%)

Query: 1530 GAEAPLPVPPPTGTAAAPAPTPSPAGGPDPT----SPSSDSGTAQAAPPLPPPPESGPGQ 1585
            G + P P PP +     P+    PAG   P     +P  D       P  PP P    G 
Sbjct: 1115 GLQGP-PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173

Query: 1586 PGWEGAPQPSPP--PPGPSTA 1604
             G  G P P  P  PPGP +A
Sbjct: 1174 AGPVGPPGPPGPPGPPGPPSA 1194



 Score = 37.7 bits (86), Expect = 0.090
 Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 13/85 (15%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAPTPSPAGGP--DPTSPSSDSGTAQAAPPLPPPP-----E 1580
            P G   P  +P P G     AP P    GP  +P  P +        PP PP       E
Sbjct: 180  PMGPSGPRGLPGPPG-----APGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGE 234

Query: 1581 SG-PGQPGWEGAPQPSPPPPGPSTA 1604
            +G PG+PG  G P P      P TA
Sbjct: 235  AGKPGRPGERGPPGPQGARGLPGTA 259



 Score = 37.7 bits (86), Expect = 0.090
 Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 16/89 (17%)

Query: 74   PAESAAVAHERPPGGTGSADPERPPGATCPES-------PGP-GPPHPLG-VVESGKGPP 124
            P    +   + P G +G A P  PPG+            PGP GPP P G   ++G   P
Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGP 1179

Query: 125  PTTEEEASGPPGEPRLDSETESDHDDAFL 153
            P       GPPG P       +  D +FL
Sbjct: 1180 P-------GPPGPPGPPGPPSAGFDFSFL 1201



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 25/75 (33%), Positives = 28/75 (37%), Gaps = 4/75 (5%)

Query: 1530 GAEAPLPVPPPTGTAAAPAPTPSPAGGPDPT-SPSSDSGTAQAAPPLPPPPESGPGQPGW 1588
            G + P     P G    P P P PAG   P  +P +D           P     PG PG 
Sbjct: 356  GPQGPRGSEGPQGVRGEPGP-PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGA 414

Query: 1589 EGAPQPSPP--PPGP 1601
             G   P  P  PPGP
Sbjct: 415  RGPSGPQGPGGPPGP 429



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 22/102 (21%)

Query: 55  PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESP-------- 106
           P+ A  PA +P A  Q      + A      PG  G+  P  P G   P  P        
Sbjct: 378 PAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPG 437

Query: 107 ---------GPGPPHPLGVVESGKGPP-PTTEEEASGPPGEP 138
                      G P P+GV    +GPP P  EE   G  GEP
Sbjct: 438 APGSKGDTGAKGEPGPVGV----QGPPGPAGEEGKRGARGEP 475



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 31/104 (29%), Positives = 38/104 (36%), Gaps = 29/104 (27%)

Query: 1528 PPGAEAPL-----PVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQA----------- 1571
            P G+E P      P PP    AA PA  P   G P     +   G A A           
Sbjct: 360  PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419

Query: 1572 --APPLPPPPESGPGQPGWEGAP-------QPSP----PPPGPS 1602
               P  PP P+   G+PG  G+        +P P     PPGP+
Sbjct: 420  PQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 29/95 (30%), Positives = 34/95 (35%), Gaps = 20/95 (21%)

Query: 1528 PPGAEAPLPVPPPTGTAA-----------APAPTPSPAGGPDPTSPSSDSGT----AQAA 1572
            PPG       P P G A             PA  P   G P P  P+ + G+      A 
Sbjct: 885  PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG 944

Query: 1573 PPLPPPPESGPGQPGWEGAP-----QPSPPPPGPS 1602
             P  P P+   GQ G  G P     +  P  PGPS
Sbjct: 945  APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS 979



 Score = 36.6 bits (83), Expect = 0.20
 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 6/71 (8%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAPT--PSPAGGPDPTSPSSDSGTA----QAAPPLPPPPES 1581
            PPGA  P     P G    P  +    P G P P   + D G A    +     PP P+ 
Sbjct: 192  PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQG 251

Query: 1582 GPGQPGWEGAP 1592
              G PG  G P
Sbjct: 252  ARGLPGTAGLP 262



 Score = 36.6 bits (83), Expect = 0.20
 Identities = 33/102 (32%), Positives = 35/102 (34%), Gaps = 37/102 (36%)

Query: 73  EPAESAAVAHERPPGGTGSADP------------------ERPPGAT---------CPES 105
           EP ++ A     PPG  G A P                    PPGAT          P  
Sbjct: 828 EPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887

Query: 106 PG-----PGPPHPLGVVESGKGP----PPTTEEEASGPPGEP 138
           P      PGPP P G  E GKGP     P       GPPG P
Sbjct: 888 PSGNAGPPGPPGPAG-KEGGKGPRGETGPAGRPGEVGPPGPP 928



 Score = 35.8 bits (81), Expect = 0.34
 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 6/85 (7%)

Query: 1529 PGAEAPLPVPPPTGTAAAPAP--TPSPAGGPDPTSPSSDSG-TAQAAPPLPPPPESGPGQ 1585
            PG       P P G A  P     P   G P       D+G    A P  PP P    G 
Sbjct: 799  PGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGA 858

Query: 1586 PGWEGAPQPSPPPPGPS--TAATGR 1608
            PG +GA + S  PPG +    A GR
Sbjct: 859  PGAKGA-RGSAGPPGATGFPGAAGR 882



 Score = 35.0 bits (79), Expect = 0.59
 Identities = 23/82 (28%), Positives = 27/82 (32%), Gaps = 8/82 (9%)

Query: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPA--------GGPDPTSPSSDSGTAQAAPPLPPPPE 1580
            PG +     P P G    P P   P         G P P   + + G A       PP  
Sbjct: 547  PGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA 606

Query: 1581 SGPGQPGWEGAPQPSPPPPGPS 1602
             GP     E   Q  P P GP+
Sbjct: 607  VGPAGKDGEAGAQGPPGPAGPA 628



 Score = 34.7 bits (78), Expect = 0.76
 Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 14/84 (16%)

Query: 1530 GAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWE 1589
            GA+     P P G    PA  P P G           G+A      PP     PG  G  
Sbjct: 833  GAKGDAGPPGPAG----PAGPPGPIGNVGAPGAKGARGSAG-----PPGATGFPGAAGRV 883

Query: 1590 GAPQPS-----PPPPGPSTAATGR 1608
            G P PS     P PPGP+    G+
Sbjct: 884  GPPGPSGNAGPPGPPGPAGKEGGK 907



 Score = 34.7 bits (78), Expect = 0.76
 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 14/79 (17%)

Query: 65  PVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPES-PG----PGPPHPLGVVES 119
           P A+ +   P  S       PPG  G    + P G T P   PG    PGPP P G    
Sbjct: 877 PGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAG---- 932

Query: 120 GKGPPPTTEEEASGPPGEP 138
            KG P      A GP G P
Sbjct: 933 EKGSP-----GADGPAGAP 946



 Score = 34.7 bits (78), Expect = 0.76
 Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 15/113 (13%)

Query: 85   PPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKG----PPPTTEEEASGPPGEPRL 140
            P G TG A P  PPG        PGPP P G   +G      P P  E+   G       
Sbjct: 1167 PRGRTGDAGPVGPPGP-------PGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRAD 1219

Query: 141  DSETESDHD---DAFLSIMSPEIQ-LPLPPGKRRTQSLSALPKERDSSSEKDG 189
            D+    D D   D  L  +S +I+ +  P G R+  + +    +   S  K G
Sbjct: 1220 DANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSG 1272



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 30/91 (32%), Positives = 32/91 (35%), Gaps = 18/91 (19%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGT-AQAAPPLPPPPESGPGQP 1586
            P G+E+P      T     P     P G   P  P    G   Q   P PP P   PG P
Sbjct: 96   PDGSESP--TDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPP 153

Query: 1587 GWEG--APQPS-------------PPPPGPS 1602
            G  G  APQ S             P P GPS
Sbjct: 154  GLGGNFAPQLSYGYDEKSTGGISVPGPMGPS 184



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 31/110 (28%), Positives = 38/110 (34%), Gaps = 33/110 (30%)

Query: 1528 PPGAEAPLPVPPPTGTAAAP-AP----------TPSPAGGPDPTSPSSDSGT--AQAAP- 1573
            P G + P   P P G +  P AP           P P G   P  P+ + G   A+  P 
Sbjct: 417  PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG 476

Query: 1574 ----PLPPPPESGPGQPGWEGA---------------PQPSPPPPGPSTA 1604
                P PP    GPG  G+ GA               P P+ P   P  A
Sbjct: 477  PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEA 526



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 25/75 (33%), Positives = 30/75 (40%), Gaps = 11/75 (14%)

Query: 1538 PPPTGTAAAPAPTPSPA--------GGPDPTSPSSDSGTAQAAPPLPPPPESG-PGQPGW 1588
            P PTG    P     P         G   P  P+ + G+   A P   P E+G PG+ G 
Sbjct: 475  PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL 534

Query: 1589 EGAP--QPSPPPPGP 1601
             GA     SP  PGP
Sbjct: 535  PGAKGLTGSPGSPGP 549



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 29/100 (29%), Positives = 32/100 (32%), Gaps = 24/100 (24%)

Query: 1529 PGAEAPLPVPPPTGTAAAPAP-----TPSPAGGP-------------DPTSPSSDSGTAQ 1570
            PGA+       P G   +P P     +P  AG P              P SP  D  T  
Sbjct: 496  PGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGP 555

Query: 1571 AAP------PLPPPPESGPGQPGWEGAPQPSPPPPGPSTA 1604
              P      P PP P    GQ G  G P P      P  A
Sbjct: 556  PGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 37/128 (28%), Positives = 43/128 (33%), Gaps = 34/128 (26%)

Query: 45  APSQPDPSVQPSEAQQP--ASHPVASNQSKEPAESAAVAHERPPGGTGS---ADPERPPG 99
           +P    P   P EA +P  A  P A   +  P          PPG  G      P  PPG
Sbjct: 513 SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG 572

Query: 100 AT-------------CPESPG-------PGPPHPLGVV----ESG-KGPP----PTTEEE 130
           A                  PG       PGPP  +G      E+G +GPP    P  E  
Sbjct: 573 ARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG 632

Query: 131 ASGPPGEP 138
             GP G P
Sbjct: 633 EQGPAGSP 640



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 25/86 (29%), Positives = 30/86 (34%), Gaps = 7/86 (8%)

Query: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAP--TPSPAGGPDPTSPSSDSG----TAQAAPPLPP 1577
            P   P     P P  PP G A  P     P   G P P+    + G         PP P 
Sbjct: 636  PAGSPGFQGLPGPAGPP-GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA 694

Query: 1578 PPESGPGQPGWEGAPQPSPPPPGPST 1603
             P    G PG +GA   +  P  P +
Sbjct: 695  GPRGANGAPGNDGAKGDAGAPGAPGS 720



 Score = 34.3 bits (77), Expect = 1.00
 Identities = 23/77 (29%), Positives = 28/77 (36%), Gaps = 5/77 (6%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPP--PPESGPGQ 1585
            PPG   P   P  +G   AP    SP     P +      T  A PP  P  P   GP  
Sbjct: 1002 PPGLAGP---PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG 1058

Query: 1586 PGWEGAPQPSPPPPGPS 1602
            P  +   +    P GP+
Sbjct: 1059 PAGKSGDRGETGPAGPA 1075



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 27/100 (27%), Positives = 32/100 (32%), Gaps = 21/100 (21%)

Query: 1520 QAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPS--------------PAGGPDPTSPSSD 1565
            Q A   +  PG      +P P G      P  +              P G P P     D
Sbjct: 721  QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD 780

Query: 1566 SGTAQAAPPLPPPPESGPGQPGWEGAPQPSPP-----PPG 1600
             G  ++ P  P  P    G PG  G P P  P     PPG
Sbjct: 781  KG--ESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPG 818



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 30/82 (36%), Positives = 33/82 (40%), Gaps = 17/82 (20%)

Query: 1528 PPGAEAPLPVPPPTGTAAAPAPT----PSPAGG---PDPTSPSSDSGTAQAAPPLPPPPE 1580
            PPG   P P PP  G   AP  +        GG   P P  PS   G       LP PP 
Sbjct: 143  PPGPPGP-PGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRG-------LPGPP- 193

Query: 1581 SGPGQPGWEGAPQPSPPPPGPS 1602
              PG  G++G P   P  PG S
Sbjct: 194  GAPGPQGFQGPPG-EPGEPGAS 214



 Score = 33.1 bits (74), Expect = 2.2
 Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 31/91 (34%)

Query: 1536 PVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAP-----PLPPPPE--SGP----- 1583
            P+ PP      PA  P   G   P+ P+  +G A+ AP     P PP P   +GP     
Sbjct: 768  PIGPP-----GPAGAPGDKGESGPSGPAGPTG-ARGAPGDRGEPGPPGPAGFAGPPGADG 821

Query: 1584 -----GQPGWEGA------PQPSPP--PPGP 1601
                 G+PG  GA      P P+ P  PPGP
Sbjct: 822  QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGP 852



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 11/90 (12%)

Query: 55  PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPES----PGP-- 108
           PS    P     A     EP          PPG  G    +  PG    +     PGP  
Sbjct: 786 PSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG 845

Query: 109 --GPPHPLGVVESGKGPPPTTEEEASGPPG 136
             GPP P+G V +   P       ++GPPG
Sbjct: 846 PAGPPGPIGNVGA---PGAKGARGSAGPPG 872



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 28/101 (27%), Positives = 34/101 (33%), Gaps = 7/101 (6%)

Query: 44  LAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCP 103
           + P  P  +  P     PA          E   +       PPG  G A  +  PGA  P
Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGP 942

Query: 104 ESPGPGPPHPLGVV--ESGKGPPPTTEEEA----SGPPGEP 138
            +  PG P P G+       G P    E       GP GEP
Sbjct: 943 -AGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP 982



 Score = 31.6 bits (70), Expect = 6.5
 Identities = 24/80 (30%), Positives = 28/80 (35%), Gaps = 14/80 (17%)

Query: 1529 PGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW 1588
            PGA  P     P G    P P  +     +P +P S   T     P P   +  PG  G 
Sbjct: 412  PGARGP---SGPQGPGGPPGPKGNSG---EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE 465

Query: 1589 EG--------APQPSPPPPG 1600
            EG         P   P PPG
Sbjct: 466  EGKRGARGEPGPTGLPGPPG 485



 Score = 31.6 bits (70), Expect = 6.5
 Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 8/85 (9%)

Query: 1523 TPTEQPPGAEAPLP-VPPPTGTAAAPAPT-----PSPAGGPD-PTSPSSDSGTAQAAPPL 1575
            +P E     EA LP     TG+  +P P      P PAG    P  P       QA    
Sbjct: 522  SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMG 581

Query: 1576 PPPPESGPGQPGWEGAPQPSPPPPG 1600
             P P+   G+PG  G  +  P PPG
Sbjct: 582  FPGPKGAAGEPGKAG-ERGVPGPPG 605



 Score = 31.2 bits (69), Expect = 8.5
 Identities = 28/97 (28%), Positives = 36/97 (37%), Gaps = 13/97 (13%)

Query: 48  QPDPSVQPSEAQQPA--SHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPES 105
           +P P   P    Q      P     + EP ++       PPG  G A  +   GA  P  
Sbjct: 564 RPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGP-- 621

Query: 106 PGPGPPHPLGVVESGKGPPPTTE-----EEASGPPGE 137
             PGP  P G  E G+  P  +         +GPPGE
Sbjct: 622 --PGPAGPAG--ERGEQGPAGSPGFQGLPGPAGPPGE 654


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.128    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,666,298
Number of Sequences: 37866
Number of extensions: 7524202
Number of successful extensions: 142857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1014
Number of HSP's successfully gapped in prelim test: 2920
Number of HSP's that attempted gapping in prelim test: 39438
Number of HSP's gapped (non-prelim): 62468
length of query: 1608
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1492
effective length of database: 13,855,062
effective search space: 20671752504
effective search space used: 20671752504
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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